2OW1A

Mmp-9 active site mutant with trifluoromethyl hydroxamate inhibitor
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
159
structure length
159
Chain Sequence
FEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGQGYSLFLVAAHQFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of MMP-9 Complexes with Five Inhibitors: Contribution of the Flexible Arg424 Side-chain to Selectivity.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Matrix metalloproteinase-9 (MMP-9) (92 kDa type IV collagena
total genus 44
structure length 159
sequence length 159
chains with identical sequence B
ec nomenclature ec 3.4.24.35: Gelatinase B.
pdb deposition date 2007-02-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2ow1A00
4I35A 4XCTA 3HB2P 3V96B 4GF1A 1MMRA 4PKTA 2X3AA 3L0VA 1ZP5A 3LJGA 3WV3A 4AIGA 2MLSA 1BUVM 1QIAA 5CZMA 4AYKA 1R1IA 5I0LA 3DPEA 1PWWA 2XS3A 1Q3AA 3F15A 2MZIA 1QICA 5JMYA 3NX7A 2WOAA 1GE6A 4WZVA 2N8RA 2W0DA 1UTZA 4FU4A 1DTHA 2OW9A 1R1HA 1YOUA 4H49A 1XFWA 4JIJA 3LQBA 3N2VA 4GR8A 1B3DA 830CA 1Z3JA 3N2UA 1O0TA 1G12A 1HFSA 1KUKA 1R55A 3Q2GA 1ZS0A 5L79A 2W13A 3ZUKA 1JIZA 3P1VA 3LKAA 4J4MA 1QUAA 4JPAA 1EUBA 3B2ZA 4HX3A 1D5JA 3I7GA 1SATA 2Z2DA 2ERQA 3HYGA 5B5OA 1AKLA 1KUHA 3DPFA 4JQGA 1PWQA 2V4BA 3TS4A 1HFCA 1AF0A 4H2EA 966CA 4PKVA 1IADA 3AYKA 2CKIA 1BQOA 3LJZA 4ON1A 5L7FA 1R1JA 1XFYA 4GQLA 1ASTA 3HBUP 4CTHA 3RTTA 2MLRA 4H1QA 5I4OA 4WKIA 2JT5A 3VTGA 4DPEA 3VI1A 1OMJA 1XUDA 1JAQA 3LIKA 1OM8A 1A85A 3EHXA 5D2BA 4GWMA 1BKCI 3USNA 1XURA 1BZSA 3MA2A 4GR0A 1J7NA 1G9KA 3LUNA 5D1TA 4I03A 4WKEA 1H71P 1FM1A 1QIBA 2DW2A 4DD8A 1BQQM 1ZVXA 2JIHA 1I76A 3KECA 3RTSA 4FVLA 3TVCA 1CAQA 1XFVA 1DMTA 2W14A 1C8TA 2SRTA 3WV1A 2PJTA 1XFXA 1GKCA 3F1AA 2FV5A 3HDBA 1MMPA 1ZXVA 2X3CA 3U1RA 2OVZA 3ZXHA 4DV8A 1G49A 4R3VA 3B8ZA 2OXZA 3TT4A 1SRPA 5D7WA 1RMZA 1CK7A 3AYUA 2CLTA 1GE7A 4GR3A 3EHYA 2POJA 3B92A 3KEJA 2YB9A 4H3XA 1YCMA 2DW0A 1KUGA 1B8YA 3WV2A 2W15A 3G42A 1YP1A 4L63A 2AYKA 1OM6A 3OHOA 3K7LA 1CXVA 2X3BA 2OVXA 5B5PA 2TCLA 1MNCA 1ZXCA 1KAPP 1UMTA 1JKYA 1SLNA 3DL1A 2W12A 1IAAA 3DNGA 1S4BP 5CXAA 3UVCA 1YQYA 1C3IA 2ERPA 5I3MA 1SU3A 1IAGA 4JA1A 4FXYP 3O2XA 1BIWA 4H82A 3DWBA 2JSDA 3LILA 3LEAA 2RJQA 5I43A 2E3XA 2AIGP 3E8RA 1JIWP 3EDGA 1GXDA 2MZEA 2WO8A 5CUHA 1UEAA 2OY2A 3HDAP 1KUFA 1JH1A 4FXQA 2USNA 4Q1LA 3O64A 3LGPA 5LABA 3HBVP 2YIGA 1SLMA 1BKCE 4JP4A 2FV9A 4A3WA 2OZRA 4AUOA 2HU6A 4HMAA 3KHIA 4IJOA 4G9LA 1IAEA 1OS2A 2O36A 1EB6A 1FLSA 3EDHA 2J0TA 4PKWA 1K7GA 2K2GA 1UMSA 1PWPA 1I73A 3LE9A 3HY7A 3K7NA 1USNA 5BOTA 2E2DA 2L0RA 3G5CA 3F17A 1CGLA 1L6JA 2RJPA 5I12A 1OO9A 5D3CA 2OW1A 1CIZA 2K9CA 4PKUA 4XM7A 3F19A 1CQRA 1BKCA 2OI0A 3ZVSA 1D7XA 4L6TA 1JJ9A 1BUDA 1D8FA 1QJJA 2DW1A 4XBHA 2WO9A 1BSWA 3TSKA 4WF6A 1SMPA 2DDYA 1XFZA 4IUWA 1BM6A 3LIRA 2Y6DA 1PWUA 1A86A 2EROA 3F18A 3I7IA 5D1SA 4EFSA 1K7QA 1GO8P 1ND1A 1CGFA 1MMQA 1Y8JA 3EDZA 3LMCA 5H8XA 2A8HA 1GKDA 4AXQA 2OXUA 3KWVC 1CGEA 1JANA 3EWJA 4PKSA 2D1OA 2J83A 3KEKA 4PKRA 2DDFA 1O0QA 1XFUA 4XM8A 3SHIA 1JAOA 3Q2HA 1OM7A 2OW0A 1ROSA 1D8MA 1GE5A 1FBLA 1PWVA 3KMEA 3P24A 2OW2A 2OY4A 1QJIA 3KMCA 1WNIA 2JT6A 5I2ZA 5D1UA 3DSLA 4GWNA 2X7MA 4L19A 4QKZA 1HTDA 4DF9A 1R54A 3AIGA 4H30A 2JNPA 3LQ0A 3OHLA 4A7BA 1XUCA 2O3EA 1ATLA 2MZHA 1Y0VA 1Y93A 4G0DA 1ZTQA 1G4KA 1GO7P 2Y6CA 1IABA 4ILWD 5BPAA 1JK3A 4WK7A 4PKQA 4GUYA 1OS9A 1RM8A 1G05A 456CA 1KBCA 3LUMA 3L0TA 4XM6A 1EAKA 3KRYA 3HY9A 3LJTA 2D1NA 2QPJA 1IACA 1I1IP 1K7IA 2OXWA 1HV5A 4IN9A 1AYKA 3BA0A 2XS4A 4H84A 3ELMA 1HOVA 1KUIA 2I47A 1MMBA 3CKIA 1HY7A 3F16A 4ZR5A 1UTTA 3GBOA 1JAPA 3EDIA 3LK8A 1C7KA 2KRJA 4H76A 5BOYA
chains in the Genus database with same CATH superfamily
4I35A 4XCTA 3HB2P 3V96B 4GF1A 1MMRA 4PKTA 2X3AA 3L0VA 1ZP5A 3LJGA 3WV3A 4AIGA 2MLSA 1BUVM 1QIAA 5CZMA 4AYKA 1R1IA 5I0LA 3DPEA 1PWWA 2XS3A 1Q3AA 3F15A 2MZIA 1QICA 5JMYA 3NX7A 2WOAA 1GE6A 4WZVA 2N8RA 2W0DA 1UTZA 4FU4A 1DTHA 2OW9A 1R1HA 1YOUA 4H49A 1XFWA 4JIJA 3LQBA 3N2VA 4GR8A 1B3DA 830CA 1Z3JA 3N2UA 1O0TA 1G12A 1HFSA 1KUKA 1R55A 3Q2GA 1ZS0A 5L79A 2W13A 3ZUKA 1JIZA 3P1VA 3LKAA 4J4MA 1QUAA 4JPAA 1EUBA 3B2ZA 4HX3A 1D5JA 3I7GA 1SATA 2Z2DA 2ERQA 3HYGA 5B5OA 1AKLA 1KUHA 3DPFA 4JQGA 1PWQA 2V4BA 3TS4A 1HFCA 1AF0A 4H2EA 966CA 4PKVA 1IADA 3AYKA 2CKIA 1BQOA 3LJZA 4ON1A 5L7FA 1R1JA 1XFYA 4GQLA 1ASTA 3HBUP 4CTHA 3RTTA 2MLRA 4H1QA 5I4OA 4WKIA 2JT5A 3VTGA 4DPEA 3VI1A 1OMJA 1XUDA 1JAQA 3LIKA 1OM8A 1A85A 3EHXA 5D2BA 4GWMA 1BKCI 3USNA 1XURA 1BZSA 3MA2A 4GR0A 1J7NA 1G9KA 3LUNA 5D1TA 4I03A 4WKEA 1H71P 1FM1A 1QIBA 2DW2A 4DD8A 1BQQM 1ZVXA 2JIHA 1I76A 3KECA 3RTSA 4FVLA 3TVCA 1CAQA 1XFVA 1DMTA 2W14A 1C8TA 2SRTA 3WV1A 2PJTA 1XFXA 1GKCA 3F1AA 2FV5A 3HDBA 1MMPA 1ZXVA 2X3CA 3DTKA 3U1RA 2OVZA 3ZXHA 4DV8A 1G49A 4R3VA 3B8ZA 2OXZA 3TT4A 1SRPA 5D7WA 1RMZA 1CK7A 3AYUA 2CLTA 1GE7A 4GR3A 3EHYA 2POJA 3B92A 3KEJA 2YB9A 4H3XA 1YCMA 2DW0A 1KUGA 1B8YA 3WV2A 2W15A 3G42A 1YP1A 4L63A 2AYKA 1OM6A 3OHOA 3K7LA 1CXVA 2X3BA 2OVXA 5B5PA 2TCLA 1MNCA 1ZXCA 1KAPP 1UMTA 1JKYA 1SLNA 3DL1A 2W12A 1IAAA 3DNGA 1S4BP 5CXAA 3UVCA 1YQYA 1C3IA 2ERPA 5I3MA 1SU3A 1IAGA 4JA1A 4FXYP 3O2XA 1BIWA 4H82A 3DWBA 1OZ9A 2JSDA 3LILA 3LEAA 2RJQA 5I43A 2E3XA 2AIGP 3E8RA 1JIWP 3EDGA 1GXDA 2MZEA 2WO8A 5CUHA 3DTIA 1UEAA 2OY2A 3HDAP 1KUFA 1JH1A 4FXQA 2USNA 4Q1LA 2YUFA 3O64A 3LGPA 5LABA 3HBVP 2YIGA 1SLMA 1BKCE 4JP4A 2FV9A 4A3WA 2OZRA 4AUOA 2HU6A 4HMAA 3KHIA 4IJOA 4G9LA 1IAEA 1OS2A 2O36A 1EB6A 1FLSA 3EDHA 2J0TA 4PKWA 1K7GA 2K2GA 1UMSA 1PWPA 1I73A 3LE9A 3HY7A 3K7NA 1USNA 5BOTA 2E2DA 2L0RA 3G5CA 3F17A 1CGLA 1L6JA 2RJPA 5I12A 1OO9A 5D3CA 2OW1A 1CIZA 2K9CA 4PKUA 4XM7A 3F19A 1CQRA 1BKCA 2OI0A 3ZVSA 1D7XA 4L6TA 1JJ9A 1BUDA 1D8FA 1QJJA 2DW1A 4XBHA 2WO9A 1BSWA 3TSKA 4WF6A 1SMPA 2DDYA 1XFZA 4IUWA 1BM6A 3LIRA 2Y6DA 1PWUA 1A86A 2EROA 3F18A 3I7IA 5D1SA 4EFSA 1K7QA 1GO8P 1ND1A 1CGFA 1MMQA 1Y8JA 3EDZA 3LMCA 5H8XA 2A8HA 1GKDA 4AXQA 2OXUA 3KWVC 1CGEA 1JANA 3EWJA 4PKSA 2D1OA 2J83A 3KEKA 4PKRA 2DDFA 1O0QA 1XFUA 4XM8A 3SHIA 1JAOA 3Q2HA 1OM7A 2OW0A 1ROSA 1D8MA 1GE5A 1FBLA 1PWVA 3KMEA 3P24A 2OW2A 2OY4A 1QJIA 3KMCA 1WNIA 2JT6A 5I2ZA 5D1UA 3DSLA 4GWNA 2X7MA 4L19A 4QKZA 1HTDA 4DF9A 1R54A 3AIGA 4H30A 2JNPA 3LQ0A 3OHLA 4A7BA 1XUCA 2O3EA 1ATLA 2MZHA 1Y0VA 4L7AA 1XM5A 1Y93A 4G0DA 1ZTQA 1G4KA 1GO7P 2Y6CA 1IABA 4ILWD 5BPAA 1JK3A 4WK7A 4PKQA 4GUYA 1OS9A 1RM8A 1G05A 456CA 1KBCA 3LUMA 3L0TA 4XM6A 1EAKA 3KRYA 3HY9A 3LJTA 2D1NA 2QPJA 1IACA 1I1IP 1K7IA 2OXWA 1HV5A 4IN9A 1AYKA 3BA0A 2XS4A 4H84A 3ELMA 1HOVA 1KUIA 2I47A 1MMBA 3CKIA 1XAXA 1HY7A 3F16A 4ZR5A 1UTTA 3GBOA 3DTEA 1JAPA 1TVIA 3EDIA 3LK8A 1C7KA 2KRJA 4H76A 5BOYA
chains in the Genus database with same CATH topology
4I35A 4XCTA 3HB2P 3V96B 4GF1A 1MMRA 4PKTA 2X3AA 3L0VA 1ZP5A 3LJGA 3WV3A 4AIGA 2MLSA 1BUVM 1QIAA 5CZMA 4AYKA 1R1IA 5I0LA 3DPEA 1PWWA 2XS3A 1Q3AA 3F15A 2MZIA 1QICA 5JMYA 3NX7A 2WOAA 1GE6A 4WZVA 2N8RA 2W0DA 1UTZA 4FU4A 1DTHA 2OW9A 1R1HA 1YOUA 4H49A 1XFWA 4JIJA 3LQBA 3N2VA 4GR8A 1B3DA 830CA 1Z3JA 3N2UA 1O0TA 1G12A 1HFSA 1KUKA 1R55A 3Q2GA 1ZS0A 5L79A 2W13A 3ZUKA 1JIZA 3P1VA 3LKAA 4J4MA 1QUAA 4JPAA 1EUBA 3B2ZA 4HX3A 1D5JA 3I7GA 1SATA 2Z2DA 2ERQA 3HYGA 5B5OA 1AKLA 1KUHA 3DPFA 4JQGA 1PWQA 2V4BA 3TS4A 1HFCA 1AF0A 4H2EA 966CA 4PKVA 1IADA 3AYKA 2CKIA 1BQOA 3LJZA 4ON1A 5L7FA 1R1JA 1XFYA 4GQLA 1ASTA 3HBUP 4CTHA 3RTTA 2MLRA 4H1QA 5I4OA 4WKIA 2JT5A 3VTGA 4DPEA 3VI1A 1OMJA 1XUDA 1JAQA 3LIKA 1OM8A 1A85A 3EHXA 5D2BA 4GWMA 1BKCI 3USNA 1XURA 1BZSA 3MA2A 4GR0A 1J7NA 1G9KA 3LUNA 5D1TA 4I03A 4WKEA 1H71P 1FM1A 1QIBA 2DW2A 4DD8A 1BQQM 1ZVXA 2JIHA 1I76A 3KECA 3RTSA 4FVLA 3TVCA 1CAQA 1XFVA 1DMTA 2W14A 1C8TA 2SRTA 3WV1A 2PJTA 1XFXA 1GKCA 3F1AA 2FV5A 3HDBA 1MMPA 1ZXVA 2X3CA 3DTKA 3U1RA 2OVZA 3ZXHA 4DV8A 1G49A 4R3VA 3B8ZA 2OXZA 3TT4A 1SRPA 5D7WA 1RMZA 1CK7A 3AYUA 2CLTA 1GE7A 4GR3A 3EHYA 2POJA 3B92A 3KEJA 2YB9A 4H3XA 1YCMA 2DW0A 1KUGA 1B8YA 3WV2A 2W15A 3G42A 1YP1A 4L63A 2AYKA 1OM6A 3OHOA 3K7LA 1CXVA 2X3BA 2OVXA 5B5PA 2TCLA 1MNCA 1ZXCA 1KAPP 1UMTA 1JKYA 1SLNA 3DL1A 2W12A 1IAAA 3DNGA 1S4BP 5CXAA 3UVCA 1YQYA 1C3IA 2ERPA 5I3MA 1SU3A 1IAGA 4JA1A 4FXYP 3O2XA 1BIWA 4H82A 3DWBA 2JSDA 3LILA 3LEAA 2RJQA 5I43A 2E3XA 2AIGP 3E8RA 1JIWP 3EDGA 1GXDA 2MZEA 2WO8A 5CUHA 3DTIA 1UEAA 2OY2A 3HDAP 1KUFA 1JH1A 4FXQA 2USNA 4Q1LA 2YUFA 3O64A 3LGPA 5LABA 3HBVP 2YIGA 1SLMA 1BKCE 4JP4A 2FV9A 4A3WA 2OZRA 4AUOA 2HU6A 4HMAA 3KHIA 4IJOA 4G9LA 1IAEA 1OS2A 2O36A 1EB6A 1FLSA 3EDHA 2J0TA 4PKWA 1K7GA 2K2GA 1UMSA 1PWPA 1I73A 3LE9A 3HY7A 3K7NA 1USNA 5BOTA 2E2DA 2L0RA 3G5CA 3F17A 1CGLA 1L6JA 2RJPA 5I12A 1OO9A 5D3CA 2OW1A 1CIZA 2K9CA 4PKUA 4XM7A 3F19A 1CQRA 1BKCA 2OI0A 3ZVSA 1D7XA 4L6TA 1JJ9A 1BUDA 1D8FA 1QJJA 2DW1A 4XBHA 2WO9A 1BSWA 3TSKA 4WF6A 1SMPA 2DDYA 1XFZA 4IUWA 1BM6A 3LIRA 2Y6DA 1PWUA 1A86A 2EROA 3F18A 3I7IA 5D1SA 4EFSA 1K7QA 1GO8P 1ND1A 1CGFA 1MMQA 1Y8JA 3EDZA 3LMCA 5H8XA 2A8HA 1GKDA 4AXQA 2OXUA 3KWVC 1CGEA 1JANA 3EWJA 4PKSA 2D1OA 2J83A 3KEKA 4PKRA 2DDFA 1O0QA 1XFUA 4XM8A 3SHIA 1JAOA 3Q2HA 1OM7A 2OW0A 1ROSA 1D8MA 1GE5A 1FBLA 1PWVA 3KMEA 3P24A 2OW2A 2OY4A 1QJIA 3KMCA 1WNIA 2JT6A 5I2ZA 5D1UA 3DSLA 4GWNA 2X7MA 4L19A 4QKZA 1HTDA 4DF9A 1R54A 3AIGA 4H30A 2JNPA 3LQ0A 3OHLA 4A7BA 1XUCA 2O3EA 1ATLA 2MZHA 1Y0VA 4L7AA 1Y93A 4G0DA 1ZTQA 1G4KA 1GO7P 2Y6CA 1IABA 4ILWD 5BPAA 1JK3A 4WK7A 4PKQA 4GUYA 1OS9A 1RM8A 1G05A 456CA 1KBCA 3LUMA 3L0TA 4XM6A 1EAKA 3KRYA 3HY9A 3LJTA 2D1NA 2QPJA 1IACA 1I1IP 1K7IA 2OXWA 1HV5A 4IN9A 1AYKA 3BA0A 2XS4A 4H84A 3ELMA 1HOVA 1KUIA 2I47A 1MMBA 3CKIA 1HY7A 3F16A 4ZR5A 1UTTA 3GBOA 3DTEA 1JAPA 3EDIA 3LK8A 1C7KA 2KRJA 4H76A 5BOYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4I35 A;  4XCT A;  3HB2 P;  3V96 B;  4GF1 A;  1MMR A;  4PKT A;  2X3A A;  3L0V A;  1ZP5 A;  3LJG A;  3WV3 A;  4AIG A;  2MLS A;  1BUV M;  1QIA A;  5CZM A;  4AYK A;  1R1I A;  5I0L A;  3DPE A;  1PWW A;  2XS3 A;  1Q3A A;  3F15 A;  2MZI A;  1QIC A;  5JMY A;  3NX7 A;  2WOA A;  1GE6 A;  4WZV A;  2N8R A;  2W0D A;  1UTZ A;  4FU4 A;  1DTH A;  2OW9 A;  1R1H A;  1YOU A;  4H49 A;  1XFW A;  4JIJ A;  3LQB A;  3N2V A;  4GR8 A;  1B3D A;  830C A;  1Z3J A;  3N2U A;  1O0T A;  1G12 A;  1HFS A;  1KUK A;  1R55 A;  3Q2G A;  1ZS0 A;  5L79 A;  2W13 A;  3ZUK A;  1JIZ A;  3P1V A;  3LKA A;  4J4M A;  1QUA A;  4JPA A;  1EUB A;  3B2Z A;  4HX3 A;  1D5J A;  3I7G A;  1SAT A;  2Z2D A;  2ERQ A;  3HYG A;  5B5O A;  1AKL A;  1KUH A;  3DPF A;  4JQG A;  1PWQ A;  2V4B A;  3TS4 A;  1HFC A;  1AF0 A;  4H2E A;  966C A;  4PKV A;  1IAD A;  3AYK A;  2CKI A;  1BQO A;  3LJZ A;  4ON1 A;  5L7F A;  1R1J A;  1XFY A;  4GQL A;  1AST A;  3HBU P;  4CTH A;  3RTT A;  2MLR A;  4H1Q A;  5I4O A;  4WKI A;  2JT5 A;  3VTG A;  4DPE A;  3VI1 A;  1OMJ A;  1XUD A;  1JAQ A;  3LIK A;  1OM8 A;  1A85 A;  3EHX A;  5D2B A;  4GWM A;  1BKC I;  3USN A;  1XUR A;  1BZS A;  3MA2 A;  4GR0 A;  1J7N A;  1G9K A;  3LUN A;  5D1T A;  4I03 A;  4WKE A;  1H71 P;  1FM1 A;  1QIB A;  2DW2 A;  4DD8 A;  1BQQ M;  1ZVX A;  2JIH A;  1I76 A;  3KEC A;  3RTS A;  4FVL A;  3TVC A;  1CAQ A;  1XFV A;  1DMT A;  2W14 A;  1C8T A;  2SRT A;  3WV1 A;  2PJT A;  1XFX A;  1GKC A;  3F1A A;  2FV5 A;  3HDB A;  1MMP A;  1ZXV A;  2X3C A;  3U1R A;  2OVZ A;  3ZXH A;  4DV8 A;  1G49 A;  4R3V A;  3B8Z A;  2OXZ A;  3TT4 A;  1SRP A;  5D7W A;  1RMZ A;  1CK7 A;  3AYU A;  2CLT A;  1GE7 A;  4GR3 A;  3EHY A;  2POJ A;  3B92 A;  3KEJ A;  2YB9 A;  4H3X A;  1YCM A;  2DW0 A;  1KUG A;  1B8Y A;  3WV2 A;  2W15 A;  3G42 A;  1YP1 A;  4L63 A;  2AYK A;  1OM6 A;  3OHO A;  3K7L A;  1CXV A;  2X3B A;  2OVX A;  5B5P A;  2TCL A;  1MNC A;  1ZXC A;  1KAP P;  1UMT A;  1JKY A;  1SLN A;  3DL1 A;  2W12 A;  1IAA A;  3DNG A;  1S4B P;  5CXA A;  3UVC A;  1YQY A;  1C3I A;  2ERP A;  5I3M A;  1SU3 A;  1IAG A;  4JA1 A;  4FXY P;  3O2X A;  1BIW A;  4H82 A;  3DWB A;  2JSD A;  3LIL A;  3LEA A;  2RJQ A;  5I43 A;  2E3X A;  2AIG P;  3E8R A;  1JIW P;  3EDG A;  1GXD A;  2MZE A;  2WO8 A;  5CUH A;  1UEA A;  2OY2 A;  3HDA P;  1KUF A;  1JH1 A;  4FXQ A;  2USN A;  4Q1L A;  3O64 A;  3LGP A;  5LAB A;  3HBV P;  2YIG A;  1SLM A;  1BKC E;  4JP4 A;  2FV9 A;  4A3W A;  2OZR A;  4AUO A;  2HU6 A;  4HMA A;  3KHI A;  4IJO A;  4G9L A;  1IAE A;  1OS2 A;  2O36 A;  1EB6 A;  1FLS A;  3EDH A;  2J0T A;  4PKW A;  1K7G A;  2K2G A;  1UMS A;  1PWP A;  1I73 A;  3LE9 A;  3HY7 A;  3K7N A;  1USN A;  5BOT A;  2E2D A;  2L0R A;  3G5C A;  3F17 A;  1CGL A;  1L6J A;  2RJP A;  5I12 A;  1OO9 A;  5D3C A;  2OW1 A;  1CIZ A;  2K9C A;  4PKU A;  4XM7 A;  3F19 A;  1CQR A;  1BKC A;  2OI0 A;  3ZVS A;  1D7X A;  4L6T A;  1JJ9 A;  1BUD A;  1D8F A;  1QJJ A;  2DW1 A;  4XBH A;  2WO9 A;  1BSW A;  3TSK A;  4WF6 A;  1SMP A;  2DDY A;  1XFZ A;  4IUW A;  1BM6 A;  3LIR A;  2Y6D A;  1PWU A;  1A86 A;  2ERO A;  3F18 A;  3I7I A;  5D1S A;  4EFS A;  1K7Q A;  1GO8 P;  1ND1 A;  1CGF A;  1MMQ A;  1Y8J A;  3EDZ A;  3LMC A;  5H8X A;  2A8H A;  1GKD A;  4AXQ A;  2OXU A;  3KWV C;  1CGE A;  1JAN A;  3EWJ A;  4PKS A;  2D1O A;  2J83 A;  3KEK A;  4PKR A;  2DDF A;  1O0Q A;  1XFU A;  4XM8 A;  3SHI A;  1JAO A;  3Q2H A;  1OM7 A;  2OW0 A;  1ROS A;  1D8M A;  1GE5 A;  1FBL A;  1PWV A;  3KME A;  3P24 A;  2OW2 A;  2OY4 A;  1QJI A;  3KMC A;  1WNI A;  2JT6 A;  5I2Z A;  5D1U A;  3DSL A;  4GWN A;  2X7M A;  4L19 A;  4QKZ A;  1HTD A;  4DF9 A;  1R54 A;  3AIG A;  4H30 A;  2JNP A;  3LQ0 A;  3OHL A;  4A7B A;  1XUC A;  2O3E A;  1ATL A;  2MZH A;  1Y0V A;  1Y93 A;  4G0D A;  1ZTQ A;  1G4K A;  1GO7 P;  2Y6C A;  1IAB A;  4ILW D;  5BPA A;  1JK3 A;  4WK7 A;  4PKQ A;  4GUY A;  1OS9 A;  1RM8 A;  1G05 A;  456C A;  1KBC A;  3LUM A;  3L0T A;  4XM6 A;  1EAK A;  3KRY A;  3HY9 A;  3LJT A;  2D1N A;  2QPJ A;  1IAC A;  1I1I P;  1K7I A;  2OXW A;  1HV5 A;  4IN9 A;  1AYK A;  3BA0 A;  2XS4 A;  4H84 A;  3ELM A;  1HOV A;  1KUI A;  2I47 A;  1MMB A;  3CKI A;  1HY7 A;  3F16 A;  4ZR5 A;  1UTT A;  3GBO A;  1JAP A;  3EDI A;  3LK8 A;  1C7K A;  2KRJ A;  4H76 A;  5BOY A; 
#chains in the Genus database with same CATH topology
 4I35 A;  4XCT A;  3HB2 P;  3V96 B;  4GF1 A;  1MMR A;  4PKT A;  2X3A A;  3L0V A;  1ZP5 A;  3LJG A;  3WV3 A;  4AIG A;  2MLS A;  1BUV M;  1QIA A;  5CZM A;  4AYK A;  1R1I A;  5I0L A;  3DPE A;  1PWW A;  2XS3 A;  1Q3A A;  3F15 A;  2MZI A;  1QIC A;  5JMY A;  3NX7 A;  2WOA A;  1GE6 A;  4WZV A;  2N8R A;  2W0D A;  1UTZ A;  4FU4 A;  1DTH A;  2OW9 A;  1R1H A;  1YOU A;  4H49 A;  1XFW A;  4JIJ A;  3LQB A;  3N2V A;  4GR8 A;  1B3D A;  830C A;  1Z3J A;  3N2U A;  1O0T A;  1G12 A;  1HFS A;  1KUK A;  1R55 A;  3Q2G A;  1ZS0 A;  5L79 A;  2W13 A;  3ZUK A;  1JIZ A;  3P1V A;  3LKA A;  4J4M A;  1QUA A;  4JPA A;  1EUB A;  3B2Z A;  4HX3 A;  1D5J A;  3I7G A;  1SAT A;  2Z2D A;  2ERQ A;  3HYG A;  5B5O A;  1AKL A;  1KUH A;  3DPF A;  4JQG A;  1PWQ A;  2V4B A;  3TS4 A;  1HFC A;  1AF0 A;  4H2E A;  966C A;  4PKV A;  1IAD A;  3AYK A;  2CKI A;  1BQO A;  3LJZ A;  4ON1 A;  5L7F A;  1R1J A;  1XFY A;  4GQL A;  1AST A;  3HBU P;  4CTH A;  3RTT A;  2MLR A;  4H1Q A;  5I4O A;  4WKI A;  2JT5 A;  3VTG A;  4DPE A;  3VI1 A;  1OMJ A;  1XUD A;  1JAQ A;  3LIK A;  1OM8 A;  1A85 A;  3EHX A;  5D2B A;  4GWM A;  1BKC I;  3USN A;  1XUR A;  1BZS A;  3MA2 A;  4GR0 A;  1J7N A;  1G9K A;  3LUN A;  5D1T A;  4I03 A;  4WKE A;  1H71 P;  1FM1 A;  1QIB A;  2DW2 A;  4DD8 A;  1BQQ M;  1ZVX A;  2JIH A;  1I76 A;  3KEC A;  3RTS A;  4FVL A;  3TVC A;  1CAQ A;  1XFV A;  1DMT A;  2W14 A;  1C8T A;  2SRT A;  3WV1 A;  2PJT A;  1XFX A;  1GKC A;  3F1A A;  2FV5 A;  3HDB A;  1MMP A;  1ZXV A;  2X3C A;  3DTK A;  3U1R A;  2OVZ A;  3ZXH A;  4DV8 A;  1G49 A;  4R3V A;  3B8Z A;  2OXZ A;  3TT4 A;  1SRP A;  5D7W A;  1RMZ A;  1CK7 A;  3AYU A;  2CLT A;  1GE7 A;  4GR3 A;  3EHY A;  2POJ A;  3B92 A;  3KEJ A;  2YB9 A;  4H3X A;  1YCM A;  2DW0 A;  1KUG A;  1B8Y A;  3WV2 A;  2W15 A;  3G42 A;  1YP1 A;  4L63 A;  2AYK A;  1OM6 A;  3OHO A;  3K7L A;  1CXV A;  2X3B A;  2OVX A;  5B5P A;  2TCL A;  1MNC A;  1ZXC A;  1KAP P;  1UMT A;  1JKY A;  1SLN A;  3DL1 A;  2W12 A;  1IAA A;  3DNG A;  1S4B P;  5CXA A;  3UVC A;  1YQY A;  1C3I A;  2ERP A;  5I3M A;  1SU3 A;  1IAG A;  4JA1 A;  4FXY P;  3O2X A;  1BIW A;  4H82 A;  3DWB A;  1OZ9 A;  2JSD A;  3LIL A;  3LEA A;  2RJQ A;  5I43 A;  2E3X A;  2AIG P;  3E8R A;  1JIW P;  3EDG A;  1GXD A;  2MZE A;  2WO8 A;  5CUH A;  3DTI A;  1UEA A;  2OY2 A;  3HDA P;  1KUF A;  1JH1 A;  4FXQ A;  2USN A;  4Q1L A;  2YUF A;  3O64 A;  3LGP A;  5LAB A;  3HBV P;  2YIG A;  1SLM A;  1BKC E;  4JP4 A;  2FV9 A;  4A3W A;  2OZR A;  4AUO A;  2HU6 A;  4HMA A;  3KHI A;  4IJO A;  4G9L A;  1IAE A;  1OS2 A;  2O36 A;  1EB6 A;  1FLS A;  3EDH A;  2J0T A;  4PKW A;  1K7G A;  2K2G A;  1UMS A;  1PWP A;  1I73 A;  3LE9 A;  3HY7 A;  3K7N A;  1USN A;  5BOT A;  2E2D A;  2L0R A;  3G5C A;  3F17 A;  1CGL A;  1L6J A;  2RJP A;  5I12 A;  1OO9 A;  5D3C A;  2OW1 A;  1CIZ A;  2K9C A;  4PKU A;  4XM7 A;  3F19 A;  1CQR A;  1BKC A;  2OI0 A;  3ZVS A;  1D7X A;  4L6T A;  1JJ9 A;  1BUD A;  1D8F A;  1QJJ A;  2DW1 A;  4XBH A;  2WO9 A;  1BSW A;  3TSK A;  4WF6 A;  1SMP A;  2DDY A;  1XFZ A;  4IUW A;  1BM6 A;  3LIR A;  2Y6D A;  1PWU A;  1A86 A;  2ERO A;  3F18 A;  3I7I A;  5D1S A;  4EFS A;  1K7Q A;  1GO8 P;  1ND1 A;  1CGF A;  1MMQ A;  1Y8J A;  3EDZ A;  3LMC A;  5H8X A;  2A8H A;  1GKD A;  4AXQ A;  2OXU A;  3KWV C;  1CGE A;  1JAN A;  3EWJ A;  4PKS A;  2D1O A;  2J83 A;  3KEK A;  4PKR A;  2DDF A;  1O0Q A;  1XFU A;  4XM8 A;  3SHI A;  1JAO A;  3Q2H A;  1OM7 A;  2OW0 A;  1ROS A;  1D8M A;  1GE5 A;  1FBL A;  1PWV A;  3KME A;  3P24 A;  2OW2 A;  2OY4 A;  1QJI A;  3KMC A;  1WNI A;  2JT6 A;  5I2Z A;  5D1U A;  3DSL A;  4GWN A;  2X7M A;  4L19 A;  4QKZ A;  1HTD A;  4DF9 A;  1R54 A;  3AIG A;  4H30 A;  2JNP A;  3LQ0 A;  3OHL A;  4A7B A;  1XUC A;  2O3E A;  1ATL A;  2MZH A;  1Y0V A;  4L7A A;  1XM5 A;  1Y93 A;  4G0D A;  1ZTQ A;  1G4K A;  1GO7 P;  2Y6C A;  1IAB A;  4ILW D;  5BPA A;  1JK3 A;  4WK7 A;  4PKQ A;  4GUY A;  1OS9 A;  1RM8 A;  1G05 A;  456C A;  1KBC A;  3LUM A;  3L0T A;  4XM6 A;  1EAK A;  3KRY A;  3HY9 A;  3LJT A;  2D1N A;  2QPJ A;  1IAC A;  1I1I P;  1K7I A;  2OXW A;  1HV5 A;  4IN9 A;  1AYK A;  3BA0 A;  2XS4 A;  4H84 A;  3ELM A;  1HOV A;  1KUI A;  2I47 A;  1MMB A;  3CKI A;  1XAX A;  1HY7 A;  3F16 A;  4ZR5 A;  1UTT A;  3GBO A;  3DTE A;  1JAP A;  1TVI A;  3EDI A;  3LK8 A;  1C7K A;  2KRJ A;  4H76 A;  5BOY A; 
#chains in the Genus database with same CATH homology
 4I35 A;  4XCT A;  3HB2 P;  3V96 B;  4GF1 A;  1MMR A;  4PKT A;  2X3A A;  3L0V A;  1ZP5 A;  3LJG A;  3WV3 A;  4AIG A;  2MLS A;  1BUV M;  1QIA A;  5CZM A;  4AYK A;  1R1I A;  5I0L A;  3DPE A;  1PWW A;  2XS3 A;  1Q3A A;  3F15 A;  2MZI A;  1QIC A;  5JMY A;  3NX7 A;  2WOA A;  1GE6 A;  4WZV A;  2N8R A;  2W0D A;  1UTZ A;  4FU4 A;  1DTH A;  2OW9 A;  1R1H A;  1YOU A;  4H49 A;  1XFW A;  4JIJ A;  3LQB A;  3N2V A;  4GR8 A;  1B3D A;  830C A;  1Z3J A;  3N2U A;  1O0T A;  1G12 A;  1HFS A;  1KUK A;  1R55 A;  3Q2G A;  1ZS0 A;  5L79 A;  2W13 A;  3ZUK A;  1JIZ A;  3P1V A;  3LKA A;  4J4M A;  1QUA A;  4JPA A;  1EUB A;  3B2Z A;  4HX3 A;  1D5J A;  3I7G A;  1SAT A;  2Z2D A;  2ERQ A;  3HYG A;  5B5O A;  1AKL A;  1KUH A;  3DPF A;  4JQG A;  1PWQ A;  2V4B A;  3TS4 A;  1HFC A;  1AF0 A;  4H2E A;  966C A;  4PKV A;  1IAD A;  3AYK A;  2CKI A;  1BQO A;  3LJZ A;  4ON1 A;  5L7F A;  1R1J A;  1XFY A;  4GQL A;  1AST A;  3HBU P;  4CTH A;  3RTT A;  2MLR A;  4H1Q A;  5I4O A;  4WKI A;  2JT5 A;  3VTG A;  4DPE A;  3VI1 A;  1OMJ A;  1XUD A;  1JAQ A;  3LIK A;  1OM8 A;  1A85 A;  3EHX A;  5D2B A;  4GWM A;  1BKC I;  3USN A;  1XUR A;  1BZS A;  3MA2 A;  4GR0 A;  1J7N A;  1G9K A;  3LUN A;  5D1T A;  4I03 A;  4WKE A;  1H71 P;  1FM1 A;  1QIB A;  2DW2 A;  4DD8 A;  1BQQ M;  1ZVX A;  2JIH A;  1I76 A;  3KEC A;  3RTS A;  4FVL A;  3TVC A;  1CAQ A;  1XFV A;  1DMT A;  2W14 A;  1C8T A;  2SRT A;  3WV1 A;  2PJT A;  1XFX A;  1GKC A;  3F1A A;  2FV5 A;  3HDB A;  1MMP A;  1ZXV A;  2X3C A;  3DTK A;  3U1R A;  2OVZ A;  3ZXH A;  4DV8 A;  1G49 A;  4R3V A;  3B8Z A;  2OXZ A;  3TT4 A;  1SRP A;  5D7W A;  1RMZ A;  1CK7 A;  3AYU A;  2CLT A;  1GE7 A;  4GR3 A;  3EHY A;  2POJ A;  3B92 A;  3KEJ A;  2YB9 A;  4H3X A;  1YCM A;  2DW0 A;  1KUG A;  1B8Y A;  3WV2 A;  2W15 A;  3G42 A;  1YP1 A;  4L63 A;  2AYK A;  1OM6 A;  3OHO A;  3K7L A;  1CXV A;  2X3B A;  2OVX A;  5B5P A;  2TCL A;  1MNC A;  1ZXC A;  1KAP P;  1UMT A;  1JKY A;  1SLN A;  3DL1 A;  2W12 A;  1IAA A;  3DNG A;  1S4B P;  5CXA A;  3UVC A;  1YQY A;  1C3I A;  2ERP A;  5I3M A;  1SU3 A;  1IAG A;  4JA1 A;  4FXY P;  3O2X A;  1BIW A;  4H82 A;  3DWB A;  2JSD A;  3LIL A;  3LEA A;  2RJQ A;  5I43 A;  2E3X A;  2AIG P;  3E8R A;  1JIW P;  3EDG A;  1GXD A;  2MZE A;  2WO8 A;  5CUH A;  3DTI A;  1UEA A;  2OY2 A;  3HDA P;  1KUF A;  1JH1 A;  4FXQ A;  2USN A;  4Q1L A;  2YUF A;  3O64 A;  3LGP A;  5LAB A;  3HBV P;  2YIG A;  1SLM A;  1BKC E;  4JP4 A;  2FV9 A;  4A3W A;  2OZR A;  4AUO A;  2HU6 A;  4HMA A;  3KHI A;  4IJO A;  4G9L A;  1IAE A;  1OS2 A;  2O36 A;  1EB6 A;  1FLS A;  3EDH A;  2J0T A;  4PKW A;  1K7G A;  2K2G A;  1UMS A;  1PWP A;  1I73 A;  3LE9 A;  3HY7 A;  3K7N A;  1USN A;  5BOT A;  2E2D A;  2L0R A;  3G5C A;  3F17 A;  1CGL A;  1L6J A;  2RJP A;  5I12 A;  1OO9 A;  5D3C A;  2OW1 A;  1CIZ A;  2K9C A;  4PKU A;  4XM7 A;  3F19 A;  1CQR A;  1BKC A;  2OI0 A;  3ZVS A;  1D7X A;  4L6T A;  1JJ9 A;  1BUD A;  1D8F A;  1QJJ A;  2DW1 A;  4XBH A;  2WO9 A;  1BSW A;  3TSK A;  4WF6 A;  1SMP A;  2DDY A;  1XFZ A;  4IUW A;  1BM6 A;  3LIR A;  2Y6D A;  1PWU A;  1A86 A;  2ERO A;  3F18 A;  3I7I A;  5D1S A;  4EFS A;  1K7Q A;  1GO8 P;  1ND1 A;  1CGF A;  1MMQ A;  1Y8J A;  3EDZ A;  3LMC A;  5H8X A;  2A8H A;  1GKD A;  4AXQ A;  2OXU A;  3KWV C;  1CGE A;  1JAN A;  3EWJ A;  4PKS A;  2D1O A;  2J83 A;  3KEK A;  4PKR A;  2DDF A;  1O0Q A;  1XFU A;  4XM8 A;  3SHI A;  1JAO A;  3Q2H A;  1OM7 A;  2OW0 A;  1ROS A;  1D8M A;  1GE5 A;  1FBL A;  1PWV A;  3KME A;  3P24 A;  2OW2 A;  2OY4 A;  1QJI A;  3KMC A;  1WNI A;  2JT6 A;  5I2Z A;  5D1U A;  3DSL A;  4GWN A;  2X7M A;  4L19 A;  4QKZ A;  1HTD A;  4DF9 A;  1R54 A;  3AIG A;  4H30 A;  2JNP A;  3LQ0 A;  3OHL A;  4A7B A;  1XUC A;  2O3E A;  1ATL A;  2MZH A;  1Y0V A;  4L7A A;  1Y93 A;  4G0D A;  1ZTQ A;  1G4K A;  1GO7 P;  2Y6C A;  1IAB A;  4ILW D;  5BPA A;  1JK3 A;  4WK7 A;  4PKQ A;  4GUY A;  1OS9 A;  1RM8 A;  1G05 A;  456C A;  1KBC A;  3LUM A;  3L0T A;  4XM6 A;  1EAK A;  3KRY A;  3HY9 A;  3LJT A;  2D1N A;  2QPJ A;  1IAC A;  1I1I P;  1K7I A;  2OXW A;  1HV5 A;  4IN9 A;  1AYK A;  3BA0 A;  2XS4 A;  4H84 A;  3ELM A;  1HOV A;  1KUI A;  2I47 A;  1MMB A;  3CKI A;  1HY7 A;  3F16 A;  4ZR5 A;  1UTT A;  3GBO A;  3DTE A;  1JAP A;  3EDI A;  3LK8 A;  1C7K A;  2KRJ A;  4H76 A;  5BOY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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