2P1HA

Rapid folding and unfolding of apaf-1 card
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
94
structure length
94
Chain Sequence
GSMDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDGIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Rapid Folding and Unfolding of Apaf-1 CARD.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Apoptosis
molecule keywords Apoptotic protease-activating factor 1
total genus 34
structure length 94
sequence length 94
ec nomenclature
pdb deposition date 2007-03-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00619 CARD Caspase recruitment domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2p1hA00
1Z6TA 4RHWE 2MS8A 2LWDA 4DWNA 2NAQA 4I16A 2YU0A 1WH4A 2NSNA 2G7RA 3T6PA 4UZ0A 1NGRA 3EZQB 1C15A 4E9MA 4N1KA 4N1JA 2P1HA 2DBGA 2YGSA 2A9IA 4O6XA 2MS7A 2N1FA 2N80A 4M9ZA 4O9LA 2NZ7A 3CRDA 2BBRA 1D2ZB 4ZBWA 1UCPA 2A5YB 4IZ7B 3LQQA 2N97A 2DBFA 4FH0A 4F42A 2DO9A 2YVIA 4A2WA 4JUPA 2M5VA 3YGSC 4P4HA 4IZ5E 4F44A 4M9SA 2DBDA 2MPCA 1CWWA 1D2ZA 4EWIA 4QOBA 4LWDA 3LQRA 1N3KA 3YGSP 4NQKA 1DDFA 2D96A 3MOPA 2KN6A 1YGOA 2VGQA 4O7QA 1E3YA 1PN5A 2OF5H 1E41A 3KATA 3J6JA 2BBZA 4RHWA 4O9FA 3EZQA 2KM6A 1WMGA 2LWEA 2MN4A 4IZAB 1WXPA 4N1LA 2N7ZA 2MB9A 4A2QA 1A1WA 2L9MA 2GF5A 2DBHA 1CY5A 4M9XA 2HM2Q 2IB1A 1DGNA 3MOPG 2O71A 3CL3A 3J63A 2N83A 2YQFA 4P4HI 2F1SA 2L6AA 4JQWA 2B1WA 1ICHA 4D8OA 1FADA 1A1ZA 3QF2A 2LS7A 2N00A 3MOPK 2OF5A
chains in the Genus database with same CATH superfamily
1Z6TA 4RHWE 2MS8A 2XV9A 2LWDA 4DWNA 2NAQA 4I16A 2YU0A 1WH4A 2NSNA 2G7RA 3T6PA 4UZ0A 1NGRA 3EZQB 1C15A 4E9MA 4N1KA 4N1JA 2P1HA 2DBGA 2YGSA 2A9IA 4O6XA 2MS7A 2N1FA 2N80A 4M9ZA 4O9LA 2NZ7A 3CRDA 2BBRA 1D2ZB 4ZBWA 1UCPA 2A5YB 4IZ7B 3LQQA 2N97A 2DBFA 4FH0A 4F42A 2DO9A 2YVIA 4A2WA 4JUPA 2M5VA 3YGSC 4P4HA 4IZ5E 4F44A 4M9SA 2DBDA 2MPCA 1CWWA 1D2ZA 4EWIA 4QOBA 4LWDA 3LQRA 1N3KA 3YGSP 4NQKA 1DDFA 2D96A 3MOPA 2KN6A 1YGOA 2VGQA 4O7QA 1E3YA 1PN5A 2OF5H 1E41A 3KATA 3J6JA 2BBZA 4RHWA 4O9FA 3EZQA 2KM6A 1WMGA 2LWEA 2MN4A 4IZAB 1WXPA 4N1LA 2N7ZA 2MB9A 4A2QA 1A1WA 2L9MA 2GF5A 2DBHA 1CY5A 4M9XA 2HM2Q 2IB1A 1DGNA 2MJMA 3MOPG 2O71A 3CL3A 3J63A 2N83A 2YQFA 4P4HI 2F1SA 2L6AA 4JQWA 2B1WA 1ICHA 4D8OA 1FADA 1A1ZA 3QF2A 2LS7A 2N00A 3MOPK 2OF5A
chains in the Genus database with same CATH topology
1Z6TA 4RHWE 2MS8A 2XV9A 2LWDA 4DWNA 2NAQA 4I16A 2YU0A 1WH4A 2NSNA 2G7RA 3T6PA 4UZ0A 1NGRA 3EZQB 1C15A 4E9MA 4N1KA 4N1JA 2P1HA 2DBGA 2YGSA 2A9IA 4O6XA 2MS7A 2N1FA 2N80A 4M9ZA 4O9LA 2NZ7A 3CRDA 2BBRA 1D2ZB 4ZBWA 1UCPA 2A5YB 4IZ7B 3LQQA 2N97A 2DBFA 4FH0A 4F42A 2DO9A 2YVIA 4A2WA 4JUPA 2M5VA 3YGSC 4P4HA 4IZ5E 4F44A 4M9SA 2DBDA 2MPCA 1CWWA 1D2ZA 4EWIA 4QOBA 4LWDA 3LQRA 1N3KA 3YGSP 4NQKA 1DDFA 2D96A 3MOPA 2KN6A 1YGOA 2VGQA 4O7QA 1E3YA 1PN5A 2OF5H 1E41A 3KATA 3J6JA 2BBZA 4RHWA 4O9FA 3EZQA 2KM6A 1WMGA 2LWEA 2MN4A 4IZAB 1WXPA 4N1LA 2N7ZA 2MB9A 4A2QA 1A1WA 2L9MA 2GF5A 2DBHA 1CY5A 4M9XA 2HM2Q 2IB1A 1DGNA 2MJMA 3MOPG 2O71A 3CL3A 3J63A 2N83A 2YQFA 4P4HI 2F1SA 2L6AA 4JQWA 2B1WA 1ICHA 4D8OA 1FADA 1A1ZA 3QF2A 2LS7A 2N00A 3MOPK 2OF5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Z6T A;  4RHW E;  2MS8 A;  2LWD A;  4DWN A;  2NAQ A;  4I16 A;  2YU0 A;  1WH4 A;  2NSN A;  2G7R A;  3T6P A;  4UZ0 A;  1NGR A;  3EZQ B;  1C15 A;  4E9M A;  4N1K A;  4N1J A;  2P1H A;  2DBG A;  2YGS A;  2A9I A;  4O6X A;  2MS7 A;  2N1F A;  2N80 A;  4M9Z A;  4O9L A;  2NZ7 A;  3CRD A;  2BBR A;  1D2Z B;  4ZBW A;  1UCP A;  2A5Y B;  4IZ7 B;  3LQQ A;  2N97 A;  2DBF A;  4FH0 A;  4F42 A;  2DO9 A;  2YVI A;  4A2W A;  4JUP A;  2M5V A;  3YGS C;  4P4H A;  4IZ5 E;  4F44 A;  4M9S A;  2DBD A;  2MPC A;  1CWW A;  1D2Z A;  4EWI A;  4QOB A;  4LWD A;  3LQR A;  1N3K A;  3YGS P;  4NQK A;  1DDF A;  2D96 A;  3MOP A;  2KN6 A;  1YGO A;  2VGQ A;  4O7Q A;  1E3Y A;  1PN5 A;  2OF5 H;  1E41 A;  3KAT A;  3J6J A;  2BBZ A;  4RHW A;  4O9F A;  3EZQ A;  2KM6 A;  1WMG A;  2LWE A;  2MN4 A;  4IZA B;  1WXP A;  4N1L A;  2N7Z A;  2MB9 A;  4A2Q A;  1A1W A;  2L9M A;  2GF5 A;  2DBH A;  1CY5 A;  4M9X A;  2HM2 Q;  2IB1 A;  1DGN A;  3MOP G;  2O71 A;  3CL3 A;  3J63 A;  2N83 A;  2YQF A;  4P4H I;  2F1S A;  2L6A A;  4JQW A;  2B1W A;  1ICH A;  4D8O A;  1FAD A;  1A1Z A;  3QF2 A;  2LS7 A;  2N00 A;  3MOP K;  2OF5 A; 
#chains in the Genus database with same CATH topology
 1Z6T A;  4RHW E;  2MS8 A;  2XV9 A;  2LWD A;  4DWN A;  2NAQ A;  4I16 A;  2YU0 A;  1WH4 A;  2NSN A;  2G7R A;  3T6P A;  4UZ0 A;  1NGR A;  3EZQ B;  1C15 A;  4E9M A;  4N1K A;  4N1J A;  2P1H A;  2DBG A;  2YGS A;  2A9I A;  4O6X A;  2MS7 A;  2N1F A;  2N80 A;  4M9Z A;  4O9L A;  2NZ7 A;  3CRD A;  2BBR A;  1D2Z B;  4ZBW A;  1UCP A;  2A5Y B;  4IZ7 B;  3LQQ A;  2N97 A;  2DBF A;  4FH0 A;  4F42 A;  2DO9 A;  2YVI A;  4A2W A;  4JUP A;  2M5V A;  3YGS C;  4P4H A;  4IZ5 E;  4F44 A;  4M9S A;  2DBD A;  2MPC A;  1CWW A;  1D2Z A;  4EWI A;  4QOB A;  4LWD A;  3LQR A;  1N3K A;  3YGS P;  4NQK A;  1DDF A;  2D96 A;  3MOP A;  2KN6 A;  1YGO A;  2VGQ A;  4O7Q A;  1E3Y A;  1PN5 A;  2OF5 H;  1E41 A;  3KAT A;  3J6J A;  2BBZ A;  4RHW A;  4O9F A;  3EZQ A;  2KM6 A;  1WMG A;  2LWE A;  2MN4 A;  4IZA B;  1WXP A;  4N1L A;  2N7Z A;  2MB9 A;  4A2Q A;  1A1W A;  2L9M A;  2GF5 A;  2DBH A;  1CY5 A;  4M9X A;  2HM2 Q;  2IB1 A;  1DGN A;  2MJM A;  3MOP G;  2O71 A;  3CL3 A;  3J63 A;  2N83 A;  2YQF A;  4P4H I;  2F1S A;  2L6A A;  4JQW A;  2B1W A;  1ICH A;  4D8O A;  1FAD A;  1A1Z A;  3QF2 A;  2LS7 A;  2N00 A;  3MOP K;  2OF5 A; 
#chains in the Genus database with same CATH homology
 1Z6T A;  4RHW E;  2MS8 A;  2XV9 A;  2LWD A;  4DWN A;  2NAQ A;  4I16 A;  2YU0 A;  1WH4 A;  2NSN A;  2G7R A;  3T6P A;  4UZ0 A;  1NGR A;  3EZQ B;  1C15 A;  4E9M A;  4N1K A;  4N1J A;  2P1H A;  2DBG A;  2YGS A;  2A9I A;  4O6X A;  2MS7 A;  2N1F A;  2N80 A;  4M9Z A;  4O9L A;  2NZ7 A;  3CRD A;  2BBR A;  1D2Z B;  4ZBW A;  1UCP A;  2A5Y B;  4IZ7 B;  3LQQ A;  2N97 A;  2DBF A;  4FH0 A;  4F42 A;  2DO9 A;  2YVI A;  4A2W A;  4JUP A;  2M5V A;  3YGS C;  4P4H A;  4IZ5 E;  4F44 A;  4M9S A;  2DBD A;  2MPC A;  1CWW A;  1D2Z A;  4EWI A;  4QOB A;  4LWD A;  3LQR A;  1N3K A;  3YGS P;  4NQK A;  1DDF A;  2D96 A;  3MOP A;  2KN6 A;  1YGO A;  2VGQ A;  4O7Q A;  1E3Y A;  1PN5 A;  2OF5 H;  1E41 A;  3KAT A;  3J6J A;  2BBZ A;  4RHW A;  4O9F A;  3EZQ A;  2KM6 A;  1WMG A;  2LWE A;  2MN4 A;  4IZA B;  1WXP A;  4N1L A;  2N7Z A;  2MB9 A;  4A2Q A;  1A1W A;  2L9M A;  2GF5 A;  2DBH A;  1CY5 A;  4M9X A;  2HM2 Q;  2IB1 A;  1DGN A;  2MJM A;  3MOP G;  2O71 A;  3CL3 A;  3J63 A;  2N83 A;  2YQF A;  4P4H I;  2F1S A;  2L6A A;  4JQW A;  2B1W A;  1ICH A;  4D8O A;  1FAD A;  1A1Z A;  3QF2 A;  2LS7 A;  2N00 A;  3MOP K;  2OF5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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