2P1HA

Rapid folding and unfolding of apaf-1 card
Total Genus 34
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
94
structure length
94
Chain Sequence
GSMDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDGIP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Rapid Folding and Unfolding of Apaf-1 CARD.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords Apoptotic protease-activating factor 1
total genus 34
structure length 94
sequence length 94
ec nomenclature
pdb deposition date 2007-03-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00619 CARD Caspase recruitment domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2p1hA00
4I16A 2GF5A 4M9ZA 4EWIA 2M5VA 3MOPA 2A5YB 3J63A 2N97A 1D2ZA 4N1LA 1CWWA 3KATA 4F44A 2N00A 2YU0A 2F1SA 2HM2Q 3YGSP 2N83A 4RHWE 1ICHA 2L9MA 2YVIA 2LS7A 1E3YA 4M9XA 1A1WA 4D8OA 2MS8A 4A2QA 2MB9A 4O7QA 2LWDA 4JQWA 4N1KA 2OF5A 2G7RA 4IZ7B 4F42A 4M9SA 1YGOA 4P4HI 2DBFA 3LQQA 3QF2A 1E41A 2P1HA 3T6PA 2MN4A 4N1JA 4P4HA 2DBHA 3J6JA 2DO9A 1D2ZB 2NSNA 4A2WA 1C15A 4FH0A 2VGQA 3LQRA 1DDFA 4IZAB 4IZ5E 2O71A 1CY5A 2N80A 3MOPK 4QOBA 1A1ZA 1NGRA 2KN6A 3EZQA 2LWEA 2YQFA 2KM6A 2NZ7A 2NAQA 4NQKA 4UZ0A 1PN5A 4O9FA 1FADA 3YGSC 2A9IA 2L6AA 1UCPA 2N1FA 3EZQB 4RHWA 2OF5H 4LWDA 2MS7A 2BBRA 3MOPG 4O6XA 2D96A 3CL3A 1WMGA 1Z6TA 4DWNA 1WH4A 2IB1A 1DGNA 2DBGA 2YGSA 1N3KA 2DBDA 4O9LA 4JUPA 4ZBWA 1WXPA 4E9MA 2B1WA 3CRDA 2BBZA 2MPCA 2N7ZA
chains in the Genus database with same CATH superfamily
4I16A 2GF5A 4M9ZA 4EWIA 2M5VA 3MOPA 2A5YB 3J63A 2N97A 1D2ZA 4N1LA 1CWWA 3KATA 4F44A 2N00A 2YU0A 2F1SA 2HM2Q 3YGSP 2N83A 4RHWE 1ICHA 2L9MA 2YVIA 2LS7A 1E3YA 4M9XA 1A1WA 4D8OA 2MS8A 4A2QA 2MB9A 4O7QA 2LWDA 4JQWA 4N1KA 2OF5A 2G7RA 2MJMA 4IZ7B 4M9SA 4F42A 1YGOA 2XV9A 4P4HI 2DBFA 3LQQA 3QF2A 1E41A 2P1HA 3T6PA 2MN4A 4N1JA 4P4HA 2DBHA 3J6JA 2DO9A 1D2ZB 2NSNA 4A2WA 1C15A 4FH0A 2VGQA 3LQRA 1DDFA 4IZAB 4IZ5E 2O71A 1CY5A 2N80A 3MOPK 4QOBA 1A1ZA 1NGRA 2KN6A 3EZQA 2LWEA 2YQFA 2KM6A 2NZ7A 2NAQA 4NQKA 4UZ0A 1PN5A 4O9FA 1FADA 3YGSC 2A9IA 2L6AA 1UCPA 2N1FA 3EZQB 4RHWA 2OF5H 4LWDA 2MS7A 2BBRA 3MOPG 4O6XA 2D96A 3CL3A 1WMGA 1Z6TA 4DWNA 1WH4A 2IB1A 1DGNA 2DBGA 2YGSA 1N3KA 2DBDA 4O9LA 4JUPA 4ZBWA 1WXPA 4E9MA 2B1WA 3CRDA 2BBZA 2MPCA 2N7ZA
chains in the Genus database with same CATH topology
4I16A 2GF5A 4M9ZA 4EWIA 2M5VA 3MOPA 2A5YB 3J63A 2N97A 1D2ZA 4N1LA 1CWWA 3KATA 4F44A 2N00A 2YU0A 2F1SA 2HM2Q 3YGSP 2N83A 4RHWE 1ICHA 2L9MA 2YVIA 2LS7A 1E3YA 4M9XA 1A1WA 4D8OA 2MS8A 4A2QA 2MB9A 4O7QA 2LWDA 4JQWA 4N1KA 2OF5A 2G7RA 2MJMA 4IZ7B 4M9SA 4F42A 1YGOA 2XV9A 4P4HI 2DBFA 3LQQA 3QF2A 1E41A 2P1HA 3T6PA 2MN4A 4N1JA 4P4HA 2DBHA 3J6JA 2DO9A 1D2ZB 2NSNA 4A2WA 1C15A 4FH0A 2VGQA 3LQRA 1DDFA 4IZAB 4IZ5E 2O71A 1CY5A 2N80A 3MOPK 4QOBA 1A1ZA 1NGRA 2KN6A 3EZQA 2LWEA 2YQFA 2KM6A 2NZ7A 2NAQA 4NQKA 4UZ0A 1PN5A 4O9FA 1FADA 3YGSC 2A9IA 2L6AA 1UCPA 2N1FA 3EZQB 4RHWA 2OF5H 4LWDA 2MS7A 2BBRA 3MOPG 4O6XA 2D96A 3CL3A 1WMGA 1Z6TA 4DWNA 1WH4A 2IB1A 1DGNA 2DBGA 2YGSA 1N3KA 2DBDA 4O9LA 4JUPA 4ZBWA 1WXPA 4E9MA 2B1WA 3CRDA 2BBZA 2MPCA 2N7ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4I16 A;  2GF5 A;  4M9Z A;  4EWI A;  2M5V A;  3MOP A;  2A5Y B;  3J63 A;  2N97 A;  1D2Z A;  4N1L A;  1CWW A;  3KAT A;  4F44 A;  2N00 A;  2YU0 A;  2F1S A;  2HM2 Q;  3YGS P;  2N83 A;  4RHW E;  1ICH A;  2L9M A;  2YVI A;  2LS7 A;  1E3Y A;  4M9X A;  1A1W A;  4D8O A;  2MS8 A;  4A2Q A;  2MB9 A;  4O7Q A;  2LWD A;  4JQW A;  4N1K A;  2OF5 A;  2G7R A;  4IZ7 B;  4F42 A;  4M9S A;  1YGO A;  4P4H I;  2DBF A;  3LQQ A;  3QF2 A;  1E41 A;  2P1H A;  3T6P A;  2MN4 A;  4N1J A;  4P4H A;  2DBH A;  3J6J A;  2DO9 A;  1D2Z B;  2NSN A;  4A2W A;  1C15 A;  4FH0 A;  2VGQ A;  3LQR A;  1DDF A;  4IZA B;  4IZ5 E;  2O71 A;  1CY5 A;  2N80 A;  3MOP K;  4QOB A;  1A1Z A;  1NGR A;  2KN6 A;  3EZQ A;  2LWE A;  2YQF A;  2KM6 A;  2NZ7 A;  2NAQ A;  4NQK A;  4UZ0 A;  1PN5 A;  4O9F A;  1FAD A;  3YGS C;  2A9I A;  2L6A A;  1UCP A;  2N1F A;  3EZQ B;  4RHW A;  2OF5 H;  4LWD A;  2MS7 A;  2BBR A;  3MOP G;  4O6X A;  2D96 A;  3CL3 A;  1WMG A;  1Z6T A;  4DWN A;  1WH4 A;  2IB1 A;  1DGN A;  2DBG A;  2YGS A;  1N3K A;  2DBD A;  4O9L A;  4JUP A;  4ZBW A;  1WXP A;  4E9M A;  2B1W A;  3CRD A;  2BBZ A;  2MPC A;  2N7Z A; 
#chains in the Genus database with same CATH topology
 4I16 A;  2GF5 A;  4M9Z A;  4EWI A;  2M5V A;  3MOP A;  2A5Y B;  3J63 A;  2N97 A;  1D2Z A;  4N1L A;  1CWW A;  3KAT A;  4F44 A;  2N00 A;  2YU0 A;  2F1S A;  2HM2 Q;  3YGS P;  2N83 A;  4RHW E;  1ICH A;  2L9M A;  2YVI A;  2LS7 A;  1E3Y A;  4M9X A;  1A1W A;  4D8O A;  2MS8 A;  4A2Q A;  2MB9 A;  4O7Q A;  2LWD A;  4JQW A;  4N1K A;  2OF5 A;  2G7R A;  2MJM A;  4IZ7 B;  4M9S A;  4F42 A;  1YGO A;  2XV9 A;  4P4H I;  2DBF A;  3LQQ A;  3QF2 A;  1E41 A;  2P1H A;  3T6P A;  2MN4 A;  4N1J A;  4P4H A;  2DBH A;  3J6J A;  2DO9 A;  1D2Z B;  2NSN A;  4A2W A;  1C15 A;  4FH0 A;  2VGQ A;  3LQR A;  1DDF A;  4IZA B;  4IZ5 E;  2O71 A;  1CY5 A;  2N80 A;  3MOP K;  4QOB A;  1A1Z A;  1NGR A;  2KN6 A;  3EZQ A;  2LWE A;  2YQF A;  2KM6 A;  2NZ7 A;  2NAQ A;  4NQK A;  4UZ0 A;  1PN5 A;  4O9F A;  1FAD A;  3YGS C;  2A9I A;  2L6A A;  1UCP A;  2N1F A;  3EZQ B;  4RHW A;  2OF5 H;  4LWD A;  2MS7 A;  2BBR A;  3MOP G;  4O6X A;  2D96 A;  3CL3 A;  1WMG A;  1Z6T A;  4DWN A;  1WH4 A;  2IB1 A;  1DGN A;  2DBG A;  2YGS A;  1N3K A;  2DBD A;  4O9L A;  4JUP A;  4ZBW A;  1WXP A;  4E9M A;  2B1W A;  3CRD A;  2BBZ A;  2MPC A;  2N7Z A; 
#chains in the Genus database with same CATH homology
 4I16 A;  2GF5 A;  4M9Z A;  4EWI A;  2M5V A;  3MOP A;  2A5Y B;  3J63 A;  2N97 A;  1D2Z A;  4N1L A;  1CWW A;  3KAT A;  4F44 A;  2N00 A;  2YU0 A;  2F1S A;  2HM2 Q;  3YGS P;  2N83 A;  4RHW E;  1ICH A;  2L9M A;  2YVI A;  2LS7 A;  1E3Y A;  4M9X A;  1A1W A;  4D8O A;  2MS8 A;  4A2Q A;  2MB9 A;  4O7Q A;  2LWD A;  4JQW A;  4N1K A;  2OF5 A;  2G7R A;  2MJM A;  4IZ7 B;  4M9S A;  4F42 A;  1YGO A;  2XV9 A;  4P4H I;  2DBF A;  3LQQ A;  3QF2 A;  1E41 A;  2P1H A;  3T6P A;  2MN4 A;  4N1J A;  4P4H A;  2DBH A;  3J6J A;  2DO9 A;  1D2Z B;  2NSN A;  4A2W A;  1C15 A;  4FH0 A;  2VGQ A;  3LQR A;  1DDF A;  4IZA B;  4IZ5 E;  2O71 A;  1CY5 A;  2N80 A;  3MOP K;  4QOB A;  1A1Z A;  1NGR A;  2KN6 A;  3EZQ A;  2LWE A;  2YQF A;  2KM6 A;  2NZ7 A;  2NAQ A;  4NQK A;  4UZ0 A;  1PN5 A;  4O9F A;  1FAD A;  3YGS C;  2A9I A;  2L6A A;  1UCP A;  2N1F A;  3EZQ B;  4RHW A;  2OF5 H;  4LWD A;  2MS7 A;  2BBR A;  3MOP G;  4O6X A;  2D96 A;  3CL3 A;  1WMG A;  1Z6T A;  4DWN A;  1WH4 A;  2IB1 A;  1DGN A;  2DBG A;  2YGS A;  1N3K A;  2DBD A;  4O9L A;  4JUP A;  4ZBW A;  1WXP A;  4E9M A;  2B1W A;  3CRD A;  2BBZ A;  2MPC A;  2N7Z A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...