2P1HA

Rapid folding and unfolding of apaf-1 card
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
94
structure length
94
Chain Sequence
GSMDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDGIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Rapid Folding and Unfolding of Apaf-1 CARD.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Apoptosis
molecule keywords Apoptotic protease-activating factor 1
total genus 34
structure length 94
sequence length 94
ec nomenclature
pdb deposition date 2007-03-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00619 CARD Caspase recruitment domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2p1hA00
2N1FA 4I16A 3LQRA 3T6PA 2N83A 1E41A 2NAQA 2YVIA 4F42A 1WH4A 2NSNA 3KATA 2N00A 2OF5A 2DBDA 1PN5A 2DBGA 1WMGA 2A5YB 1YGOA 2NZ7A 1Z6TA 2F1SA 4NQKA 2LS7A 2MPCA 4A2WA 4IZ7B 4N1KA 4IZ5E 4RHWE 1E3YA 2KM6A 2MN4A 1N3KA 3J63A 1WXPA 4DWNA 2G7RA 3CL3A 2DBFA 4FH0A 4JUPA 2A9IA 4EWIA 1C15A 1NGRA 2MB9A 3LQQA 4UZ0A 4P4HA 2D96A 3EZQB 4RHWA 1DGNA 4O7QA 3MOPK 1UCPA 3J6JA 1ICHA 2HM2Q 1D2ZA 2B1WA 1A1WA 4E9MA 1A1ZA 2N7ZA 2N97A 2IB1A 2YU0A 2BBZA 1DDFA 2BBRA 3EZQA 4IZAB 4D8OA 1D2ZB 2YQFA 1FADA 2DBHA 4P4HI 1CY5A 2N80A 1CWWA 4O9LA 3YGSC 2L9MA 4N1JA 4QOBA 3MOPG 4N1LA 4A2QA 4O6XA 2LWDA 2L6AA 4JQWA 4M9XA 2GF5A 2MS7A 2LWEA 2YGSA 2M5VA 3QF2A 4F44A 2P1HA 3CRDA 4M9SA 4O9FA 2VGQA 4LWDA 4M9ZA 2MS8A 2O71A 3YGSP 2KN6A 2OF5H 3MOPA 2DO9A 4ZBWA
chains in the Genus database with same CATH superfamily
2N1FA 4I16A 3LQRA 3T6PA 2N83A 1E41A 2NAQA 2YVIA 4F42A 1WH4A 2NSNA 3KATA 2N00A 2OF5A 2DBDA 1PN5A 2DBGA 1WMGA 2A5YB 1YGOA 2NZ7A 1Z6TA 2F1SA 4NQKA 2LS7A 2MPCA 4A2WA 4IZ7B 4N1KA 4IZ5E 4RHWE 1E3YA 2KM6A 2MN4A 1N3KA 3J63A 1WXPA 4DWNA 2G7RA 3CL3A 2DBFA 4FH0A 2XV9A 4JUPA 2A9IA 4EWIA 1C15A 1NGRA 2MB9A 3LQQA 4UZ0A 4P4HA 2D96A 3EZQB 4RHWA 1DGNA 4O7QA 3MOPK 1UCPA 3J6JA 1ICHA 2HM2Q 2MJMA 1D2ZA 2B1WA 1A1WA 4E9MA 1A1ZA 2N7ZA 2N97A 2IB1A 2YU0A 2BBZA 1DDFA 2BBRA 3EZQA 4IZAB 4D8OA 1D2ZB 2YQFA 1FADA 2DBHA 4P4HI 1CY5A 2N80A 1CWWA 4O9LA 3YGSC 2L9MA 4N1JA 4QOBA 3MOPG 4N1LA 4A2QA 4O6XA 2LWDA 2L6AA 4JQWA 4M9XA 2GF5A 2MS7A 2LWEA 2YGSA 2M5VA 3QF2A 4F44A 2P1HA 3CRDA 4M9SA 4O9FA 2VGQA 4LWDA 4M9ZA 2MS8A 2O71A 3YGSP 2KN6A 2OF5H 3MOPA 2DO9A 4ZBWA
chains in the Genus database with same CATH topology
2N1FA 4I16A 3LQRA 3T6PA 2N83A 1E41A 2NAQA 2YVIA 4F42A 1WH4A 2NSNA 3KATA 2N00A 2OF5A 2DBDA 1PN5A 2DBGA 1WMGA 2A5YB 1YGOA 2NZ7A 1Z6TA 2F1SA 4NQKA 2LS7A 2MPCA 4A2WA 4IZ7B 4N1KA 4IZ5E 4RHWE 1E3YA 2KM6A 2MN4A 1N3KA 3J63A 1WXPA 4DWNA 2G7RA 3CL3A 2DBFA 4FH0A 2XV9A 4JUPA 2A9IA 4EWIA 1C15A 1NGRA 2MB9A 3LQQA 4UZ0A 4P4HA 2D96A 3EZQB 4RHWA 1DGNA 4O7QA 3MOPK 1UCPA 3J6JA 1ICHA 2HM2Q 2MJMA 1D2ZA 2B1WA 1A1WA 4E9MA 1A1ZA 2N7ZA 2N97A 2IB1A 2YU0A 2BBZA 1DDFA 2BBRA 3EZQA 4IZAB 4D8OA 1D2ZB 2YQFA 1FADA 2DBHA 4P4HI 1CY5A 2N80A 1CWWA 4O9LA 3YGSC 2L9MA 4N1JA 4QOBA 3MOPG 4N1LA 4A2QA 4O6XA 2LWDA 2L6AA 4JQWA 4M9XA 2GF5A 2MS7A 2LWEA 2YGSA 2M5VA 3QF2A 4F44A 2P1HA 3CRDA 4M9SA 4O9FA 2VGQA 4LWDA 4M9ZA 2MS8A 2O71A 3YGSP 2KN6A 2OF5H 3MOPA 2DO9A 4ZBWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2N1F A;  4I16 A;  3LQR A;  3T6P A;  2N83 A;  1E41 A;  2NAQ A;  2YVI A;  4F42 A;  1WH4 A;  2NSN A;  3KAT A;  2N00 A;  2OF5 A;  2DBD A;  1PN5 A;  2DBG A;  1WMG A;  2A5Y B;  1YGO A;  2NZ7 A;  1Z6T A;  2F1S A;  4NQK A;  2LS7 A;  2MPC A;  4A2W A;  4IZ7 B;  4N1K A;  4IZ5 E;  4RHW E;  1E3Y A;  2KM6 A;  2MN4 A;  1N3K A;  3J63 A;  1WXP A;  4DWN A;  2G7R A;  3CL3 A;  2DBF A;  4FH0 A;  4JUP A;  2A9I A;  4EWI A;  1C15 A;  1NGR A;  2MB9 A;  3LQQ A;  4UZ0 A;  4P4H A;  2D96 A;  3EZQ B;  4RHW A;  1DGN A;  4O7Q A;  3MOP K;  1UCP A;  3J6J A;  1ICH A;  2HM2 Q;  1D2Z A;  2B1W A;  1A1W A;  4E9M A;  1A1Z A;  2N7Z A;  2N97 A;  2IB1 A;  2YU0 A;  2BBZ A;  1DDF A;  2BBR A;  3EZQ A;  4IZA B;  4D8O A;  1D2Z B;  2YQF A;  1FAD A;  2DBH A;  4P4H I;  1CY5 A;  2N80 A;  1CWW A;  4O9L A;  3YGS C;  2L9M A;  4N1J A;  4QOB A;  3MOP G;  4N1L A;  4A2Q A;  4O6X A;  2LWD A;  2L6A A;  4JQW A;  4M9X A;  2GF5 A;  2MS7 A;  2LWE A;  2YGS A;  2M5V A;  3QF2 A;  4F44 A;  2P1H A;  3CRD A;  4M9S A;  4O9F A;  2VGQ A;  4LWD A;  4M9Z A;  2MS8 A;  2O71 A;  3YGS P;  2KN6 A;  2OF5 H;  3MOP A;  2DO9 A;  4ZBW A; 
#chains in the Genus database with same CATH topology
 2N1F A;  4I16 A;  3LQR A;  3T6P A;  2N83 A;  1E41 A;  2NAQ A;  2YVI A;  4F42 A;  1WH4 A;  2NSN A;  3KAT A;  2N00 A;  2OF5 A;  2DBD A;  1PN5 A;  2DBG A;  1WMG A;  2A5Y B;  1YGO A;  2NZ7 A;  1Z6T A;  2F1S A;  4NQK A;  2LS7 A;  2MPC A;  4A2W A;  4IZ7 B;  4N1K A;  4IZ5 E;  4RHW E;  1E3Y A;  2KM6 A;  2MN4 A;  1N3K A;  3J63 A;  1WXP A;  4DWN A;  2G7R A;  3CL3 A;  2DBF A;  4FH0 A;  2XV9 A;  4JUP A;  2A9I A;  4EWI A;  1C15 A;  1NGR A;  2MB9 A;  3LQQ A;  4UZ0 A;  4P4H A;  2D96 A;  3EZQ B;  4RHW A;  1DGN A;  4O7Q A;  3MOP K;  1UCP A;  3J6J A;  1ICH A;  2HM2 Q;  2MJM A;  1D2Z A;  2B1W A;  1A1W A;  4E9M A;  1A1Z A;  2N7Z A;  2N97 A;  2IB1 A;  2YU0 A;  2BBZ A;  1DDF A;  2BBR A;  3EZQ A;  4IZA B;  4D8O A;  1D2Z B;  2YQF A;  1FAD A;  2DBH A;  4P4H I;  1CY5 A;  2N80 A;  1CWW A;  4O9L A;  3YGS C;  2L9M A;  4N1J A;  4QOB A;  3MOP G;  4N1L A;  4A2Q A;  4O6X A;  2LWD A;  2L6A A;  4JQW A;  4M9X A;  2GF5 A;  2MS7 A;  2LWE A;  2YGS A;  2M5V A;  3QF2 A;  4F44 A;  2P1H A;  3CRD A;  4M9S A;  4O9F A;  2VGQ A;  4LWD A;  4M9Z A;  2MS8 A;  2O71 A;  3YGS P;  2KN6 A;  2OF5 H;  3MOP A;  2DO9 A;  4ZBW A; 
#chains in the Genus database with same CATH homology
 2N1F A;  4I16 A;  3LQR A;  3T6P A;  2N83 A;  1E41 A;  2NAQ A;  2YVI A;  4F42 A;  1WH4 A;  2NSN A;  3KAT A;  2N00 A;  2OF5 A;  2DBD A;  1PN5 A;  2DBG A;  1WMG A;  2A5Y B;  1YGO A;  2NZ7 A;  1Z6T A;  2F1S A;  4NQK A;  2LS7 A;  2MPC A;  4A2W A;  4IZ7 B;  4N1K A;  4IZ5 E;  4RHW E;  1E3Y A;  2KM6 A;  2MN4 A;  1N3K A;  3J63 A;  1WXP A;  4DWN A;  2G7R A;  3CL3 A;  2DBF A;  4FH0 A;  2XV9 A;  4JUP A;  2A9I A;  4EWI A;  1C15 A;  1NGR A;  2MB9 A;  3LQQ A;  4UZ0 A;  4P4H A;  2D96 A;  3EZQ B;  4RHW A;  1DGN A;  4O7Q A;  3MOP K;  1UCP A;  3J6J A;  1ICH A;  2HM2 Q;  2MJM A;  1D2Z A;  2B1W A;  1A1W A;  4E9M A;  1A1Z A;  2N7Z A;  2N97 A;  2IB1 A;  2YU0 A;  2BBZ A;  1DDF A;  2BBR A;  3EZQ A;  4IZA B;  4D8O A;  1D2Z B;  2YQF A;  1FAD A;  2DBH A;  4P4H I;  1CY5 A;  2N80 A;  1CWW A;  4O9L A;  3YGS C;  2L9M A;  4N1J A;  4QOB A;  3MOP G;  4N1L A;  4A2Q A;  4O6X A;  2LWD A;  2L6A A;  4JQW A;  4M9X A;  2GF5 A;  2MS7 A;  2LWE A;  2YGS A;  2M5V A;  3QF2 A;  4F44 A;  2P1H A;  3CRD A;  4M9S A;  4O9F A;  2VGQ A;  4LWD A;  4M9Z A;  2MS8 A;  2O71 A;  3YGS P;  2KN6 A;  2OF5 H;  3MOP A;  2DO9 A;  4ZBW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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