2P3TA

Crystal structure of human factor xa complexed with 3-chloro-4-(2-methylamino-imidazol-1-ylmethyl)-thiophene-2-carboxylic acid [4-chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-6-methoxy-phenyl]-amide
Total Genus 12
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
52
structure length
52
Chain Sequence
KLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Thiophene-anthranilamides as highly potent and orally available factor xa inhibitors.
pubmed doi rcsb
molecule tags Blood clotting
molecule keywords Coagulation factor X
total genus 12
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2007-03-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2p3tA00
1YUFA 4RRXA 2UWPB 2EI7B 2Y7ZB 2BZ6L 4O02B 3LAQA 3CENL 2NPRA 5KIRA 2RNLA 1O5DL 3P5BL 5L30L 4Z0LA 2VJ3A 2OYUP 1IQKL 3HO4A 4MMYB 1DVAL 4TGFA 2P28B 4JZEL 4BXSA 1UZQA 4JZFL 1EPIA 1XKBA 4JYUL 2F9BL 1CEJA 2Y5HL 4LORA 1Z6EL 1HRFA 3NJPC 3FCSB 1CCVA 5FDQA 2Y5GL 2WFTA 3N8YB 3FFGL 2AYLA 3Q3KB 1F7MA 1YUGA 1IQIL 5F19A 1K37A 4CUEA 1L3YA 4M11A 4ZXXL 3SOVA 2FLGA 3NTBA 3K9XA 3NT1A 2Y82B 3EGFA 3SW2A 2W2NE 3TGFA 4Y79B 5JB9E 3HPTA 3LTGD 1I0UA 2XC4L 1URKA 1AUTL 3QH0A 1IQNL 2Q1JB 3ASIA 4NGAL 1V3XB 2KB9A 3H5CB 4RRZA 1IQGL 2W3KB 2UWOB 2XC5L 1WHFA 2FD6A 3ZYJB 4D0FA 3KQDL 4CSYA 2FZZL 1TLEA 4COXA 5CISA 2XBXL 4JYVL 4XBMA 1JBUL 4LMFA 4CUDA 2XBWL 1X7AL 1DX5I 1PXXA 2VWNL 2BMGA 3KQEL 4BXWA 4XLWA 1EQGA 2J4IB 2VH0B 1G1SA 4ZAEB 2OYEP 4A7IA 2P26A 2WPIE 4M10A 2ADXA 4ZH8B 1MQ6L 3TK5B 2P16L 3TK6B 1XKAL 4OTYA 1HJ7A 1FJSL 1K36A 3F1SB 2TGFA 2J38B 2PHBB 1Z6CA 1EPGA 2BQ7A 2J2UB 2PUQL 3N8WB 4C16A 1CQEA 3IITB 4G1MB 2WG4B 1EMNA 1HREA 4RRYA 1APOA 5CKMA 5CKNA 3V64C 3R05A 3TBDA 1HZ8A 3U7UG 2J94B 2FLRL 4X8SL 1DIYA 2P3TA 4NG9L 2EI8B 1LQDA 4ISIL 3LIWB 1KSNB 5JW1A 3KCGL 5L2ZL 5JBBE 4Z0KB 1B9WA 3KQCL 1G2MB 1U67A 4YZUB 1BF9A 2J95B 1GK5A 3KQBL 1HT5A 3MDLA 1FAKL 2WYGB 2BQ6A 2PR3B 1IGXA 3BPSE 3KK6A 5JVYA 2BOXA 3LC5B 1WU1B 1IQML 3CFWA 2D1JB 4ZHAB 2P93L 3HS7A 1DDXA 1IJQA 1RFNB 2KL7A 1APQA 1Q4GA 1UZPA 2VWMK 2DDUA 3QCWA 1N1IA 3Q7DA 1COUA 3MQEA 1CCFA 1ATDA 4E1GA 2VH6B 1KIGL 1UZKA 5EGMB 2M74A 5COXA 2VVVL 2WPLE 1EPJA 2MHPA 3LN1A 2BOKL 5CKQA 3N8YA 1LMJA 1IOXA 1EPHA 1HX2A 3LC3B 2P3FN 2WPME 1F0SB 4YT7L 4Z6AL 3M37L 5E8DA 2W26B 3GISX 2P95L 3OLUA 3ENSA 4Y6DB 6COXA 5IKQA 1HCGB 1HT8A 1XDTR 2P3UA 3N8VA 5IKRA 4ISHL 2K2SB 3N8ZA 2VVCK 1FFMA 3N8XA 2XC0L 4PH9A 4XL1A 1NFXB 2MGRA 3BT1A 5I46L 1LPKA 4Y7BB 1ADXA 1IP0A 3HS5A 1KLIL 1IGZA 3LN0A 3DEMA 2P94L 2JKHL 1KLOA 1NPEB 1YO8A 1LPZA 2B7DL 1IQLL 1F7EA 1NZIA 3HS6A 1KLJL 3HO5A 1P9JA 2I9AA 2BOHA 1G1QA 4D90A 1F0RB 4BTUA 1FE2A 3PGHA 1EAIC 1LPGA 2WYJB 1TOZA 1IQJL 3TH3L 3HO3A 2W86A 2XBYL 2GD4A 1G2LB 2I9BA 1CVUA 1OB1C 3NTGA 5JBAE 3SOBB 4Y71B 2WG3C 2Y80B 2VVUL 2H9EL 2YGOA 1U8CB 4X8VL 4MMXB 2G00L 1EQHA 2W3IB 1JL9A 1PGEA 2EI6B 3M36L 3KRKA 2CJIB 2BOUA 2WFXB 2RA0L 3QMOA 1WHEA 3CA7A 1G1TA 1IQFL 1ATBA 4Y76B 3ZYIB 1XFEA 4RS0A 1PTHA 4RUTA 1NFUB 1W7XL 5F1AA 2FLBL 1FSBA 2YGPA 3TZIA 1P0SL 1M1XB 4RRWA 1PFXL 1YUKB 2VWOL 1SZBA 4CUFA 4AQTA 4X8UL 5JVZA 1JV2B 5JB8E 2UWLB 4JZDL 2WPKE 2RHPA 1IOEL 1NFWB 3CS7L 1CVWL 2W2PE 2WPHE 4MMZB 4NA9L 5JBCE 3U73A 2WPJE 3ZYGA 4BDWA 1NQLB 3C9AC 1ZAQA 4X8TL 1IQEL 4OTJA 3GCXE 4BDXA 5KN5C 1MOXC 1W8BL 4FM5A 3POYA 1PRHA 1DQBA 4BTIA 2Y81B 5IKVA 1C5MF 1G1RA 2W2OE 2MGPA 2BO2A 4BTTA 1EBVA 1MQ5L 3KL6B 2W2ME 3N8WA 1CX2A 3ELAL 2J34B 1A3PA 3LTFB 2VWLL 1ATEA 2Y5FL 1EMOA 1FF7A 2W2QE 3V65B 1L5GB 1QFKL 3IJEB 4ZXYL 3GCWE 1IVOC 4D0EA 1EZQB 4Y7AB 1TPGA 5L2YL 1FAXL 3OLTA 1HAFA 1ATAA 2BQWA 2P3FL 3SOQA 2XBVL 2Y38A 2KV4A 1YGCL 3RR3A 1NFYB 2K2TA 4O1ZA 5IKTA 4YT6L 1EGFA 1UZJA 1NT0A 1IQHL 1J9CL 3FBYA 1HAEA 3BT2A 5K0HB 2Y7XB 1N7DA 3F6UL
chains in the Genus database with same CATH superfamily
1QIUA 1YUFA 4RRXA 2UWPB 2EI7B 2Y7ZB 2BZ6L 4O02B 3LAQA 3CENL 2NPRA 5KIRA 2RNLA 1O5DL 3P5BL 5L30L 4Z0LA 2JJLA 2VJ3A 2OYUP 1IQKL 3HO4A 4MMYB 1DVAL 4TGFA 2P28B 4JZEL 4BXSA 1UZQA 4JZFL 1EPIA 1XKBA 4JYUL 2F9BL 1CEJA 2Y5HL 4LORA 1Z6EL 1HRFA 3NJPC 3FCSB 1CCVA 5FDQA 2Y5GL 2WFTA 3N8YB 1KKEA 3FFGL 2AYLA 3Q3KB 1F7MA 1YUGA 1IQIL 5F19A 1K37A 4CUEA 1L3YA 4M11A 4ZXXL 3SOVA 2FLGA 3NTBA 3K9XA 3NT1A 2Y82B 3EGFA 3SW2A 2W2NE 3TGFA 4Y79B 5JB9E 3HPTA 3LTGD 1I0UA 2XC4L 1URKA 1AUTL 3QH0A 1IQNL 2Q1JB 3ASIA 4NGAL 1V3XB 2KB9A 3H5CB 4RRZA 1IQGL 2W3KB 2UWOB 2XC5L 1WHFA 2FD6A 3ZYJB 4D0FA 3KQDL 4CSYA 2FZZL 1TLEA 4COXA 5CISA 2XBXL 4JYVL 4XBMA 1JBUL 4LMFA 4CUDA 2BSFA 2XBWL 1X7AL 1DX5I 1PXXA 2VWNL 2BMGA 2YGQA 3KQEL 2HORA 4BXWA 4XLWA 1EQGA 2J4IB 2VH0B 1G1SA 4ZAEB 2OYEP 4A7IA 2P26A 2WPIE 4M10A 2ADXA 4ZH8B 1MQ6L 3TK5B 2P16L 3TK6B 1XKAL 4OTYA 1HJ7A 1FJSL 1K36A 3F1SB 2BT8A 2TGFA 2J38B 2PHBB 1Z6CA 1EPGA 2BQ7A 2J2UB 2PUQL 3N8WB 4C16A 2BT7A 1V1IA 1CQEA 3IITB 4G1MB 2WG4B 1EMNA 1HREA 4RRYA 1APOA 5CKMA 5CKNA 3V64C 3R05A 3TBDA 1HZ8A 3U7UG 2J94B 2FLRL 4GU4A 4X8SL 1DIYA 2P3TA 4NG9L 2EI8B 1LQDA 4ISIL 3LIWB 1KSNB 5JW1A 3KCGL 5L2ZL 5JBBE 4Z0KB 1B9WA 3KQCL 1G2MB 1U67A 4YZUB 1BF9A 2J95B 1GK5A 3KQBL 1HT5A 3MDLA 1FAKL 2WYGB 2BQ6A 2PR3B 1IGXA 3BPSE 3KK6A 2WZPP 5JVYA 2BOXA 3LC5B 1WU1B 1IQML 3CFWA 2D1JB 4ZHAB 2P93L 3HS7A 1DDXA 1IJQA 1RFNB 2KL7A 1APQA 1Q4GA 1UZPA 2VWMK 2DDUA 3QCWA 1N1IA 3Q7DA 1COUA 3MQEA 1CCFA 1ATDA 4E1GA 2VH6B 1KIGL 1UZKA 5EGMB 2M74A 5COXA 2VVVL 2WPLE 1EPJA 2MHPA 3LN1A 2BOKL 5CKQA 3N8YA 1LMJA 1IOXA 1EPHA 1HX2A 3LC3B 2P3FN 2WPME 1F0SB 4YT7L 4Z6AL 3M37L 5E8DA 2W26B 3GISX 1LMMA 2P95L 3OLUA 3ENSA 4Y6DB 6COXA 5IKQA 1HCGB 1HT8A 1XDTR 2P3UA 3N8VA 5IKRA 4ISHL 2K2SB 3N8ZA 2VVCK 1FFMA 3N8XA 2XC0L 4PH9A 4XL1A 1NFXB 3S6XA 2MGRA 3BT1A 5I46L 1LPKA 4Y7BB 1ADXA 1IP0A 3HS5A 4GU3A 1KLIL 1IGZA 3LN0A 3DEMA 2P94L 2JKHL 1KLOA 4A94C 1NPEB 1YO8A 1LPZA 2B7DL 1IQLL 1F7EA 1NZIA 3HS6A 1KLJL 3HO5A 1P9JA 2I9AA 2BOHA 1G1QA 4D90A 1F0RB 4BTUA 1FE2A 3PGHA 1EAIC 1LPGA 2WYJB 1TOZA 1IQJL 3TH3L 3HO3A 2W86A 2XBYL 2GD4A 1G2LB 2I9BA 1CVUA 1OB1C 3NTGA 5JBAE 2HOXA 3SOBB 4Y71B 2WG3C 2Y80B 2VVUL 2H9EL 2YGOA 1U8CB 4X8VL 4MMXB 2G00L 1EQHA 2W3IB 1JL9A 1PGEA 2EI6B 3M36L 3KRKA 2CJIB 2BOUA 2WFXB 2RA0L 3QMOA 1WHEA 3CA7A 1G1TA 1IQFL 1ATBA 4Y76B 3ZYIB 1XFEA 4RS0A 1PTHA 4RUTA 1NFUB 1W7XL 5F1AA 2FLBL 1FSBA 2YGPA 3TZIA 1P0SL 1M1XB 4RRWA 1PFXL 1YUKB 2VWOL 1SZBA 4CUFA 4AQTA 4X8UL 5JVZA 1JV2B 5JB8E 2UWLB 4JZDL 2WPKE 2RHPA 1IOEL 1NFWB 3CS7L 1CVWL 2W2PE 2WPHE 4MMZB 4NA9L 5JBCE 3U73A 2WPJE 3ZYGA 4BDWA 1NQLB 3C9AC 1ZAQA 4X8TL 1IQEL 4OTJA 3GCXE 4BDXA 5KN5C 1MOXC 1W8BL 4FM5A 1V1HA 3POYA 1PRHA 1DQBA 4BTIA 2H9EC 2Y81B 5IKVA 1C5MF 1G1RA 2W2OE 2MGPA 2BO2A 4BTTA 1EBVA 1MQ5L 3KL6B 2W2ME 3N8WA 1CX2A 3ELAL 2J34B 1A3PA 3LTFB 2VWLL 1ATEA 2Y5FL 1EMOA 1FF7A 2W2QE 3V65B 1L5GB 1QFKL 2VRSA 3IJEB 4ZXYL 3GCWE 1IVOC 4D0EA 1EZQB 4Y7AB 1TPGA 5L2YL 1FAXL 3OLTA 1HAFA 1ATAA 2BQWA 2P3FL 3SOQA 2XBVL 2Y38A 2KV4A 1YGCL 3RR3A 1NFYB 2KNIA 2K2TA 4O1ZA 5IKTA 4YT6L 1EGFA 1UZJA 1NT0A 1IQHL 1LK9A 1J9CL 3FBYA 1HAEA 3BT2A 5K0HB 2Y7XB 1N7DA 3F6UL
chains in the Genus database with same CATH topology
1YUFA 4RRXA 2UWPB 2EI7B 2Y7ZB 2BZ6L 4O02B 3LAQA 3CENL 2NPRA 5KIRA 2RNLA 1O5DL 3P5BL 5L30L 4Z0LA 2VJ3A 2OYUP 1IQKL 3HO4A 4MMYB 1DVAL 4TGFA 2P28B 4JZEL 4BXSA 1UZQA 4JZFL 1EPIA 1XKBA 4JYUL 2F9BL 1CEJA 2Y5HL 4LORA 1Z6EL 1HRFA 3NJPC 3FCSB 1CCVA 5FDQA 2Y5GL 2WFTA 3N8YB 3FFGL 2AYLA 3Q3KB 1F7MA 1YUGA 1IQIL 5F19A 1K37A 4CUEA 1L3YA 4M11A 4ZXXL 3SOVA 2FLGA 3NTBA 3K9XA 3NT1A 2Y82B 3EGFA 3SW2A 2W2NE 3TGFA 4Y79B 5JB9E 3HPTA 3LTGD 1I0UA 2XC4L 1URKA 1AUTL 3QH0A 1IQNL 2Q1JB 3ASIA 4NGAL 1V3XB 2KB9A 3H5CB 4RRZA 1IQGL 2W3KB 2UWOB 2XC5L 1WHFA 2FD6A 3ZYJB 4D0FA 3KQDL 4CSYA 2FZZL 1TLEA 4COXA 5CISA 2XBXL 4JYVL 4XBMA 1JBUL 4LMFA 4CUDA 2XBWL 1X7AL 1DX5I 1PXXA 2VWNL 2BMGA 2YGQA 3KQEL 4BXWA 4XLWA 1EQGA 2J4IB 2VH0B 1G1SA 4ZAEB 2OYEP 4A7IA 2P26A 2WPIE 4M10A 2ADXA 4ZH8B 1MQ6L 3TK5B 2P16L 3TK6B 1XKAL 4OTYA 1HJ7A 1FJSL 1K36A 3F1SB 2TGFA 2J38B 2PHBB 1Z6CA 1EPGA 2BQ7A 2J2UB 2PUQL 3N8WB 4C16A 1CQEA 3IITB 4G1MB 2WG4B 1EMNA 1HREA 4RRYA 1APOA 5CKMA 5CKNA 3V64C 3R05A 3TBDA 1HZ8A 3U7UG 2J94B 2FLRL 4X8SL 1DIYA 2P3TA 4NG9L 2EI8B 1LQDA 4ISIL 3LIWB 1KSNB 5JW1A 3KCGL 5L2ZL 5JBBE 4Z0KB 1B9WA 3KQCL 1G2MB 1U67A 4YZUB 1BF9A 2J95B 1GK5A 3KQBL 1HT5A 3MDLA 1FAKL 2WYGB 2BQ6A 2PR3B 1IGXA 3BPSE 3KK6A 2WZPP 5JVYA 2BOXA 3LC5B 1WU1B 1IQML 3CFWA 2D1JB 4ZHAB 2P93L 3HS7A 1DDXA 1IJQA 1RFNB 2KL7A 1APQA 1Q4GA 1UZPA 2VWMK 2DDUA 3QCWA 1N1IA 3Q7DA 1COUA 3MQEA 1CCFA 1ATDA 4E1GA 2VH6B 1KIGL 1UZKA 5EGMB 2M74A 5COXA 2VVVL 2WPLE 1EPJA 2MHPA 3LN1A 2BOKL 5CKQA 3N8YA 1LMJA 1IOXA 1EPHA 1HX2A 3LC3B 2P3FN 2WPME 1F0SB 4YT7L 4Z6AL 3M37L 5E8DA 2W26B 3GISX 1LMMA 2P95L 3OLUA 3ENSA 4Y6DB 6COXA 5IKQA 1HCGB 1HT8A 1XDTR 2P3UA 3N8VA 5IKRA 4ISHL 2K2SB 3N8ZA 2VVCK 1FFMA 3N8XA 2XC0L 4PH9A 4XL1A 1NFXB 3S6XA 2MGRA 3BT1A 5I46L 1LPKA 4Y7BB 1ADXA 1IP0A 3HS5A 1KLIL 1IGZA 3LN0A 3DEMA 2P94L 2JKHL 1KLOA 4A94C 1NPEB 1YO8A 1LPZA 2B7DL 1IQLL 1F7EA 1NZIA 3HS6A 1KLJL 3HO5A 1P9JA 2I9AA 2BOHA 1G1QA 4D90A 1F0RB 4BTUA 1FE2A 3PGHA 1EAIC 1LPGA 2WYJB 1TOZA 1IQJL 3TH3L 3HO3A 2W86A 2XBYL 2GD4A 1G2LB 2I9BA 1CVUA 1OB1C 3NTGA 5JBAE 3SOBB 4Y71B 2WG3C 2Y80B 2VVUL 2H9EL 2YGOA 1U8CB 4X8VL 4MMXB 2G00L 1EQHA 2W3IB 1JL9A 1PGEA 2EI6B 3M36L 3KRKA 2CJIB 2BOUA 2WFXB 2RA0L 3QMOA 1WHEA 3CA7A 1G1TA 1IQFL 1ATBA 4Y76B 3ZYIB 1XFEA 4RS0A 1PTHA 4RUTA 1NFUB 1W7XL 5F1AA 2FLBL 1FSBA 2YGPA 3TZIA 1P0SL 1M1XB 4RRWA 1PFXL 1YUKB 2VWOL 1SZBA 4CUFA 4AQTA 4X8UL 5JVZA 1JV2B 5JB8E 2UWLB 4JZDL 2WPKE 2RHPA 1IOEL 1NFWB 3CS7L 1CVWL 2W2PE 2WPHE 4MMZB 4NA9L 5JBCE 3U73A 2WPJE 3ZYGA 4BDWA 1NQLB 3C9AC 1ZAQA 4X8TL 1IQEL 4OTJA 3GCXE 4BDXA 5KN5C 1MOXC 1W8BL 4FM5A 3POYA 1PRHA 1DQBA 4BTIA 2H9EC 2Y81B 5IKVA 1C5MF 1G1RA 2W2OE 2MGPA 2BO2A 4BTTA 1EBVA 1MQ5L 3KL6B 2W2ME 3N8WA 1CX2A 3ELAL 2J34B 1A3PA 3LTFB 2VWLL 1ATEA 2Y5FL 1EMOA 1FF7A 2W2QE 3V65B 1L5GB 1QFKL 3IJEB 4ZXYL 3GCWE 1IVOC 4D0EA 1EZQB 4Y7AB 1TPGA 5L2YL 1FAXL 3OLTA 1HAFA 1ATAA 2BQWA 2P3FL 3SOQA 2XBVL 2Y38A 2KV4A 1YGCL 3RR3A 1NFYB 2KNIA 2K2TA 4O1ZA 5IKTA 4YT6L 1EGFA 1UZJA 1NT0A 1IQHL 1J9CL 3FBYA 1HAEA 3BT2A 5K0HB 2Y7XB 1N7DA 3F6UL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YUF A;  4RRX A;  2UWP B;  2EI7 B;  2Y7Z B;  2BZ6 L;  4O02 B;  3LAQ A;  3CEN L;  2NPR A;  5KIR A;  2RNL A;  1O5D L;  3P5B L;  5L30 L;  4Z0L A;  2VJ3 A;  2OYU P;  1IQK L;  3HO4 A;  4MMY B;  1DVA L;  4TGF A;  2P28 B;  4JZE L;  4BXS A;  1UZQ A;  4JZF L;  1EPI A;  1XKB A;  4JYU L;  2F9B L;  1CEJ A;  2Y5H L;  4LOR A;  1Z6E L;  1HRF A;  3NJP C;  3FCS B;  1CCV A;  5FDQ A;  2Y5G L;  2WFT A;  3N8Y B;  3FFG L;  2AYL A;  3Q3K B;  1F7M A;  1YUG A;  1IQI L;  5F19 A;  1K37 A;  4CUE A;  1L3Y A;  4M11 A;  4ZXX L;  3SOV A;  2FLG A;  3NTB A;  3K9X A;  3NT1 A;  2Y82 B;  3EGF A;  3SW2 A;  2W2N E;  3TGF A;  4Y79 B;  5JB9 E;  3HPT A;  3LTG D;  1I0U A;  2XC4 L;  1URK A;  1AUT L;  3QH0 A;  1IQN L;  2Q1J B;  3ASI A;  4NGA L;  1V3X B;  2KB9 A;  3H5C B;  4RRZ A;  1IQG L;  2W3K B;  2UWO B;  2XC5 L;  1WHF A;  2FD6 A;  3ZYJ B;  4D0F A;  3KQD L;  4CSY A;  2FZZ L;  1TLE A;  4COX A;  5CIS A;  2XBX L;  4JYV L;  4XBM A;  1JBU L;  4LMF A;  4CUD A;  2XBW L;  1X7A L;  1DX5 I;  1PXX A;  2VWN L;  2BMG A;  3KQE L;  4BXW A;  4XLW A;  1EQG A;  2J4I B;  2VH0 B;  1G1S A;  4ZAE B;  2OYE P;  4A7I A;  2P26 A;  2WPI E;  4M10 A;  2ADX A;  4ZH8 B;  1MQ6 L;  3TK5 B;  2P16 L;  3TK6 B;  1XKA L;  4OTY A;  1HJ7 A;  1FJS L;  1K36 A;  3F1S B;  2TGF A;  2J38 B;  2PHB B;  1Z6C A;  1EPG A;  2BQ7 A;  2J2U B;  2PUQ L;  3N8W B;  4C16 A;  1CQE A;  3IIT B;  4G1M B;  2WG4 B;  1EMN A;  1HRE A;  4RRY A;  1APO A;  5CKM A;  5CKN A;  3V64 C;  3R05 A;  3TBD A;  1HZ8 A;  3U7U G;  2J94 B;  2FLR L;  4X8S L;  1DIY A;  2P3T A;  4NG9 L;  2EI8 B;  1LQD A;  4ISI L;  3LIW B;  1KSN B;  5JW1 A;  3KCG L;  5L2Z L;  5JBB E;  4Z0K B;  1B9W A;  3KQC L;  1G2M B;  1U67 A;  4YZU B;  1BF9 A;  2J95 B;  1GK5 A;  3KQB L;  1HT5 A;  3MDL A;  1FAK L;  2WYG B;  2BQ6 A;  2PR3 B;  1IGX A;  3BPS E;  3KK6 A;  5JVY A;  2BOX A;  3LC5 B;  1WU1 B;  1IQM L;  3CFW A;  2D1J B;  4ZHA B;  2P93 L;  3HS7 A;  1DDX A;  1IJQ A;  1RFN B;  2KL7 A;  1APQ A;  1Q4G A;  1UZP A;  2VWM K;  2DDU A;  3QCW A;  1N1I A;  3Q7D A;  1COU A;  3MQE A;  1CCF A;  1ATD A;  4E1G A;  2VH6 B;  1KIG L;  1UZK A;  5EGM B;  2M74 A;  5COX A;  2VVV L;  2WPL E;  1EPJ A;  2MHP A;  3LN1 A;  2BOK L;  5CKQ A;  3N8Y A;  1LMJ A;  1IOX A;  1EPH A;  1HX2 A;  3LC3 B;  2P3F N;  2WPM E;  1F0S B;  4YT7 L;  4Z6A L;  3M37 L;  5E8D A;  2W26 B;  3GIS X;  2P95 L;  3OLU A;  3ENS A;  4Y6D B;  6COX A;  5IKQ A;  1HCG B;  1HT8 A;  1XDT R;  2P3U A;  3N8V A;  5IKR A;  4ISH L;  2K2S B;  3N8Z A;  2VVC K;  1FFM A;  3N8X A;  2XC0 L;  4PH9 A;  4XL1 A;  1NFX B;  2MGR A;  3BT1 A;  5I46 L;  1LPK A;  4Y7B B;  1ADX A;  1IP0 A;  3HS5 A;  1KLI L;  1IGZ A;  3LN0 A;  3DEM A;  2P94 L;  2JKH L;  1KLO A;  1NPE B;  1YO8 A;  1LPZ A;  2B7D L;  1IQL L;  1F7E A;  1NZI A;  3HS6 A;  1KLJ L;  3HO5 A;  1P9J A;  2I9A A;  2BOH A;  1G1Q A;  4D90 A;  1F0R B;  4BTU A;  1FE2 A;  3PGH A;  1EAI C;  1LPG A;  2WYJ B;  1TOZ A;  1IQJ L;  3TH3 L;  3HO3 A;  2W86 A;  2XBY L;  2GD4 A;  1G2L B;  2I9B A;  1CVU A;  1OB1 C;  3NTG A;  5JBA E;  3SOB B;  4Y71 B;  2WG3 C;  2Y80 B;  2VVU L;  2H9E L;  2YGO A;  1U8C B;  4X8V L;  4MMX B;  2G00 L;  1EQH A;  2W3I B;  1JL9 A;  1PGE A;  2EI6 B;  3M36 L;  3KRK A;  2CJI B;  2BOU A;  2WFX B;  2RA0 L;  3QMO A;  1WHE A;  3CA7 A;  1G1T A;  1IQF L;  1ATB A;  4Y76 B;  3ZYI B;  1XFE A;  4RS0 A;  1PTH A;  4RUT A;  1NFU B;  1W7X L;  5F1A A;  2FLB L;  1FSB A;  2YGP A;  3TZI A;  1P0S L;  1M1X B;  4RRW A;  1PFX L;  1YUK B;  2VWO L;  1SZB A;  4CUF A;  4AQT A;  4X8U L;  5JVZ A;  1JV2 B;  5JB8 E;  2UWL B;  4JZD L;  2WPK E;  2RHP A;  1IOE L;  1NFW B;  3CS7 L;  1CVW L;  2W2P E;  2WPH E;  4MMZ B;  4NA9 L;  5JBC E;  3U73 A;  2WPJ E;  3ZYG A;  4BDW A;  1NQL B;  3C9A C;  1ZAQ A;  4X8T L;  1IQE L;  4OTJ A;  3GCX E;  4BDX A;  5KN5 C;  1MOX C;  1W8B L;  4FM5 A;  3POY A;  1PRH A;  1DQB A;  4BTI A;  2Y81 B;  5IKV A;  1C5M F;  1G1R A;  2W2O E;  2MGP A;  2BO2 A;  4BTT A;  1EBV A;  1MQ5 L;  3KL6 B;  2W2M E;  3N8W A;  1CX2 A;  3ELA L;  2J34 B;  1A3P A;  3LTF B;  2VWL L;  1ATE A;  2Y5F L;  1EMO A;  1FF7 A;  2W2Q E;  3V65 B;  1L5G B;  1QFK L;  3IJE B;  4ZXY L;  3GCW E;  1IVO C;  4D0E A;  1EZQ B;  4Y7A B;  1TPG A;  5L2Y L;  1FAX L;  3OLT A;  1HAF A;  1ATA A;  2BQW A;  2P3F L;  3SOQ A;  2XBV L;  2Y38 A;  2KV4 A;  1YGC L;  3RR3 A;  1NFY B;  2K2T A;  4O1Z A;  5IKT A;  4YT6 L;  1EGF A;  1UZJ A;  1NT0 A;  1IQH L;  1J9C L;  3FBY A;  1HAE A;  3BT2 A;  5K0H B;  2Y7X B;  1N7D A;  3F6U L; 
#chains in the Genus database with same CATH topology
 1QIU A;  1YUF A;  4RRX A;  2UWP B;  2EI7 B;  2Y7Z B;  2BZ6 L;  4O02 B;  3LAQ A;  3CEN L;  2NPR A;  5KIR A;  2RNL A;  1O5D L;  3P5B L;  5L30 L;  4Z0L A;  2JJL A;  2VJ3 A;  2OYU P;  1IQK L;  3HO4 A;  4MMY B;  1DVA L;  4TGF A;  2P28 B;  4JZE L;  4BXS A;  1UZQ A;  4JZF L;  1EPI A;  1XKB A;  4JYU L;  2F9B L;  1CEJ A;  2Y5H L;  4LOR A;  1Z6E L;  1HRF A;  3NJP C;  3FCS B;  1CCV A;  5FDQ A;  2Y5G L;  2WFT A;  3N8Y B;  1KKE A;  3FFG L;  2AYL A;  3Q3K B;  1F7M A;  1YUG A;  1IQI L;  5F19 A;  1K37 A;  4CUE A;  1L3Y A;  4M11 A;  4ZXX L;  3SOV A;  2FLG A;  3NTB A;  3K9X A;  3NT1 A;  2Y82 B;  3EGF A;  3SW2 A;  2W2N E;  3TGF A;  4Y79 B;  5JB9 E;  3HPT A;  3LTG D;  1I0U A;  2XC4 L;  1URK A;  1AUT L;  3QH0 A;  1IQN L;  2Q1J B;  3ASI A;  4NGA L;  1V3X B;  2KB9 A;  3H5C B;  4RRZ A;  1IQG L;  2W3K B;  2UWO B;  2XC5 L;  1WHF A;  2FD6 A;  3ZYJ B;  4D0F A;  3KQD L;  4CSY A;  2FZZ L;  1TLE A;  4COX A;  5CIS A;  2XBX L;  4JYV L;  4XBM A;  1JBU L;  4LMF A;  4CUD A;  2BSF A;  2XBW L;  1X7A L;  1DX5 I;  1PXX A;  2VWN L;  2BMG A;  2YGQ A;  3KQE L;  2HOR A;  4BXW A;  4XLW A;  1EQG A;  2J4I B;  2VH0 B;  1G1S A;  4ZAE B;  2OYE P;  4A7I A;  2P26 A;  2WPI E;  4M10 A;  2ADX A;  4ZH8 B;  1MQ6 L;  3TK5 B;  2P16 L;  3TK6 B;  1XKA L;  4OTY A;  1HJ7 A;  1FJS L;  1K36 A;  3F1S B;  2BT8 A;  2TGF A;  2J38 B;  2PHB B;  1Z6C A;  1EPG A;  2BQ7 A;  2J2U B;  2PUQ L;  3N8W B;  4C16 A;  2BT7 A;  1V1I A;  1CQE A;  3IIT B;  4G1M B;  2WG4 B;  1EMN A;  1HRE A;  4RRY A;  1APO A;  5CKM A;  5CKN A;  3V64 C;  3R05 A;  3TBD A;  1HZ8 A;  3U7U G;  2J94 B;  2FLR L;  4GU4 A;  4X8S L;  1DIY A;  2P3T A;  4NG9 L;  2EI8 B;  1LQD A;  4ISI L;  3LIW B;  1KSN B;  5JW1 A;  3KCG L;  5L2Z L;  5JBB E;  4Z0K B;  1B9W A;  3KQC L;  1G2M B;  1U67 A;  4YZU B;  1BF9 A;  2J95 B;  1GK5 A;  3KQB L;  1HT5 A;  3MDL A;  1FAK L;  2WYG B;  2BQ6 A;  2PR3 B;  1IGX A;  3BPS E;  3KK6 A;  2WZP P;  5JVY A;  2BOX A;  3LC5 B;  1WU1 B;  1IQM L;  3CFW A;  2D1J B;  4ZHA B;  2P93 L;  3HS7 A;  1DDX A;  1IJQ A;  1RFN B;  2KL7 A;  1APQ A;  1Q4G A;  1UZP A;  2VWM K;  2DDU A;  3QCW A;  1N1I A;  3Q7D A;  1COU A;  3MQE A;  1CCF A;  1ATD A;  4E1G A;  2VH6 B;  1KIG L;  1UZK A;  5EGM B;  2M74 A;  5COX A;  2VVV L;  2WPL E;  1EPJ A;  2MHP A;  3LN1 A;  2BOK L;  5CKQ A;  3N8Y A;  1LMJ A;  1IOX A;  1EPH A;  1HX2 A;  3LC3 B;  2P3F N;  2WPM E;  1F0S B;  4YT7 L;  4Z6A L;  3M37 L;  5E8D A;  2W26 B;  3GIS X;  1LMM A;  2P95 L;  3OLU A;  3ENS A;  4Y6D B;  6COX A;  5IKQ A;  1HCG B;  1HT8 A;  1XDT R;  2P3U A;  3N8V A;  5IKR A;  4ISH L;  2K2S B;  3N8Z A;  2VVC K;  1FFM A;  3N8X A;  2XC0 L;  4PH9 A;  4XL1 A;  1NFX B;  3S6X A;  2MGR A;  3BT1 A;  5I46 L;  1LPK A;  4Y7B B;  1ADX A;  1IP0 A;  3HS5 A;  4GU3 A;  1KLI L;  1IGZ A;  3LN0 A;  3DEM A;  2P94 L;  2JKH L;  1KLO A;  4A94 C;  1NPE B;  1YO8 A;  1LPZ A;  2B7D L;  1IQL L;  1F7E A;  1NZI A;  3HS6 A;  1KLJ L;  3HO5 A;  1P9J A;  2I9A A;  2BOH A;  1G1Q A;  4D90 A;  1F0R B;  4BTU A;  1FE2 A;  3PGH A;  1EAI C;  1LPG A;  2WYJ B;  1TOZ A;  1IQJ L;  3TH3 L;  3HO3 A;  2W86 A;  2XBY L;  2GD4 A;  1G2L B;  2I9B A;  1CVU A;  1OB1 C;  3NTG A;  5JBA E;  2HOX A;  3SOB B;  4Y71 B;  2WG3 C;  2Y80 B;  2VVU L;  2H9E L;  2YGO A;  1U8C B;  4X8V L;  4MMX B;  2G00 L;  1EQH A;  2W3I B;  1JL9 A;  1PGE A;  2EI6 B;  3M36 L;  3KRK A;  2CJI B;  2BOU A;  2WFX B;  2RA0 L;  3QMO A;  1WHE A;  3CA7 A;  1G1T A;  1IQF L;  1ATB A;  4Y76 B;  3ZYI B;  1XFE A;  4RS0 A;  1PTH A;  4RUT A;  1NFU B;  1W7X L;  5F1A A;  2FLB L;  1FSB A;  2YGP A;  3TZI A;  1P0S L;  1M1X B;  4RRW A;  1PFX L;  1YUK B;  2VWO L;  1SZB A;  4CUF A;  4AQT A;  4X8U L;  5JVZ A;  1JV2 B;  5JB8 E;  2UWL B;  4JZD L;  2WPK E;  2RHP A;  1IOE L;  1NFW B;  3CS7 L;  1CVW L;  2W2P E;  2WPH E;  4MMZ B;  4NA9 L;  5JBC E;  3U73 A;  2WPJ E;  3ZYG A;  4BDW A;  1NQL B;  3C9A C;  1ZAQ A;  4X8T L;  1IQE L;  4OTJ A;  3GCX E;  4BDX A;  5KN5 C;  1MOX C;  1W8B L;  4FM5 A;  1V1H A;  3POY A;  1PRH A;  1DQB A;  4BTI A;  2H9E C;  2Y81 B;  5IKV A;  1C5M F;  1G1R A;  2W2O E;  2MGP A;  2BO2 A;  4BTT A;  1EBV A;  1MQ5 L;  3KL6 B;  2W2M E;  3N8W A;  1CX2 A;  3ELA L;  2J34 B;  1A3P A;  3LTF B;  2VWL L;  1ATE A;  2Y5F L;  1EMO A;  1FF7 A;  2W2Q E;  3V65 B;  1L5G B;  1QFK L;  2VRS A;  3IJE B;  4ZXY L;  3GCW E;  1IVO C;  4D0E A;  1EZQ B;  4Y7A B;  1TPG A;  5L2Y L;  1FAX L;  3OLT A;  1HAF A;  1ATA A;  2BQW A;  2P3F L;  3SOQ A;  2XBV L;  2Y38 A;  2KV4 A;  1YGC L;  3RR3 A;  1NFY B;  2KNI A;  2K2T A;  4O1Z A;  5IKT A;  4YT6 L;  1EGF A;  1UZJ A;  1NT0 A;  1IQH L;  1LK9 A;  1J9C L;  3FBY A;  1HAE A;  3BT2 A;  5K0H B;  2Y7X B;  1N7D A;  3F6U L; 
#chains in the Genus database with same CATH homology
 1YUF A;  4RRX A;  2UWP B;  2EI7 B;  2Y7Z B;  2BZ6 L;  4O02 B;  3LAQ A;  3CEN L;  2NPR A;  5KIR A;  2RNL A;  1O5D L;  3P5B L;  5L30 L;  4Z0L A;  2VJ3 A;  2OYU P;  1IQK L;  3HO4 A;  4MMY B;  1DVA L;  4TGF A;  2P28 B;  4JZE L;  4BXS A;  1UZQ A;  4JZF L;  1EPI A;  1XKB A;  4JYU L;  2F9B L;  1CEJ A;  2Y5H L;  4LOR A;  1Z6E L;  1HRF A;  3NJP C;  3FCS B;  1CCV A;  5FDQ A;  2Y5G L;  2WFT A;  3N8Y B;  3FFG L;  2AYL A;  3Q3K B;  1F7M A;  1YUG A;  1IQI L;  5F19 A;  1K37 A;  4CUE A;  1L3Y A;  4M11 A;  4ZXX L;  3SOV A;  2FLG A;  3NTB A;  3K9X A;  3NT1 A;  2Y82 B;  3EGF A;  3SW2 A;  2W2N E;  3TGF A;  4Y79 B;  5JB9 E;  3HPT A;  3LTG D;  1I0U A;  2XC4 L;  1URK A;  1AUT L;  3QH0 A;  1IQN L;  2Q1J B;  3ASI A;  4NGA L;  1V3X B;  2KB9 A;  3H5C B;  4RRZ A;  1IQG L;  2W3K B;  2UWO B;  2XC5 L;  1WHF A;  2FD6 A;  3ZYJ B;  4D0F A;  3KQD L;  4CSY A;  2FZZ L;  1TLE A;  4COX A;  5CIS A;  2XBX L;  4JYV L;  4XBM A;  1JBU L;  4LMF A;  4CUD A;  2XBW L;  1X7A L;  1DX5 I;  1PXX A;  2VWN L;  2BMG A;  2YGQ A;  3KQE L;  4BXW A;  4XLW A;  1EQG A;  2J4I B;  2VH0 B;  1G1S A;  4ZAE B;  2OYE P;  4A7I A;  2P26 A;  2WPI E;  4M10 A;  2ADX A;  4ZH8 B;  1MQ6 L;  3TK5 B;  2P16 L;  3TK6 B;  1XKA L;  4OTY A;  1HJ7 A;  1FJS L;  1K36 A;  3F1S B;  2TGF A;  2J38 B;  2PHB B;  1Z6C A;  1EPG A;  2BQ7 A;  2J2U B;  2PUQ L;  3N8W B;  4C16 A;  1CQE A;  3IIT B;  4G1M B;  2WG4 B;  1EMN A;  1HRE A;  4RRY A;  1APO A;  5CKM A;  5CKN A;  3V64 C;  3R05 A;  3TBD A;  1HZ8 A;  3U7U G;  2J94 B;  2FLR L;  4X8S L;  1DIY A;  2P3T A;  4NG9 L;  2EI8 B;  1LQD A;  4ISI L;  3LIW B;  1KSN B;  5JW1 A;  3KCG L;  5L2Z L;  5JBB E;  4Z0K B;  1B9W A;  3KQC L;  1G2M B;  1U67 A;  4YZU B;  1BF9 A;  2J95 B;  1GK5 A;  3KQB L;  1HT5 A;  3MDL A;  1FAK L;  2WYG B;  2BQ6 A;  2PR3 B;  1IGX A;  3BPS E;  3KK6 A;  2WZP P;  5JVY A;  2BOX A;  3LC5 B;  1WU1 B;  1IQM L;  3CFW A;  2D1J B;  4ZHA B;  2P93 L;  3HS7 A;  1DDX A;  1IJQ A;  1RFN B;  2KL7 A;  1APQ A;  1Q4G A;  1UZP A;  2VWM K;  2DDU A;  3QCW A;  1N1I A;  3Q7D A;  1COU A;  3MQE A;  1CCF A;  1ATD A;  4E1G A;  2VH6 B;  1KIG L;  1UZK A;  5EGM B;  2M74 A;  5COX A;  2VVV L;  2WPL E;  1EPJ A;  2MHP A;  3LN1 A;  2BOK L;  5CKQ A;  3N8Y A;  1LMJ A;  1IOX A;  1EPH A;  1HX2 A;  3LC3 B;  2P3F N;  2WPM E;  1F0S B;  4YT7 L;  4Z6A L;  3M37 L;  5E8D A;  2W26 B;  3GIS X;  1LMM A;  2P95 L;  3OLU A;  3ENS A;  4Y6D B;  6COX A;  5IKQ A;  1HCG B;  1HT8 A;  1XDT R;  2P3U A;  3N8V A;  5IKR A;  4ISH L;  2K2S B;  3N8Z A;  2VVC K;  1FFM A;  3N8X A;  2XC0 L;  4PH9 A;  4XL1 A;  1NFX B;  3S6X A;  2MGR A;  3BT1 A;  5I46 L;  1LPK A;  4Y7B B;  1ADX A;  1IP0 A;  3HS5 A;  1KLI L;  1IGZ A;  3LN0 A;  3DEM A;  2P94 L;  2JKH L;  1KLO A;  4A94 C;  1NPE B;  1YO8 A;  1LPZ A;  2B7D L;  1IQL L;  1F7E A;  1NZI A;  3HS6 A;  1KLJ L;  3HO5 A;  1P9J A;  2I9A A;  2BOH A;  1G1Q A;  4D90 A;  1F0R B;  4BTU A;  1FE2 A;  3PGH A;  1EAI C;  1LPG A;  2WYJ B;  1TOZ A;  1IQJ L;  3TH3 L;  3HO3 A;  2W86 A;  2XBY L;  2GD4 A;  1G2L B;  2I9B A;  1CVU A;  1OB1 C;  3NTG A;  5JBA E;  3SOB B;  4Y71 B;  2WG3 C;  2Y80 B;  2VVU L;  2H9E L;  2YGO A;  1U8C B;  4X8V L;  4MMX B;  2G00 L;  1EQH A;  2W3I B;  1JL9 A;  1PGE A;  2EI6 B;  3M36 L;  3KRK A;  2CJI B;  2BOU A;  2WFX B;  2RA0 L;  3QMO A;  1WHE A;  3CA7 A;  1G1T A;  1IQF L;  1ATB A;  4Y76 B;  3ZYI B;  1XFE A;  4RS0 A;  1PTH A;  4RUT A;  1NFU B;  1W7X L;  5F1A A;  2FLB L;  1FSB A;  2YGP A;  3TZI A;  1P0S L;  1M1X B;  4RRW A;  1PFX L;  1YUK B;  2VWO L;  1SZB A;  4CUF A;  4AQT A;  4X8U L;  5JVZ A;  1JV2 B;  5JB8 E;  2UWL B;  4JZD L;  2WPK E;  2RHP A;  1IOE L;  1NFW B;  3CS7 L;  1CVW L;  2W2P E;  2WPH E;  4MMZ B;  4NA9 L;  5JBC E;  3U73 A;  2WPJ E;  3ZYG A;  4BDW A;  1NQL B;  3C9A C;  1ZAQ A;  4X8T L;  1IQE L;  4OTJ A;  3GCX E;  4BDX A;  5KN5 C;  1MOX C;  1W8B L;  4FM5 A;  3POY A;  1PRH A;  1DQB A;  4BTI A;  2H9E C;  2Y81 B;  5IKV A;  1C5M F;  1G1R A;  2W2O E;  2MGP A;  2BO2 A;  4BTT A;  1EBV A;  1MQ5 L;  3KL6 B;  2W2M E;  3N8W A;  1CX2 A;  3ELA L;  2J34 B;  1A3P A;  3LTF B;  2VWL L;  1ATE A;  2Y5F L;  1EMO A;  1FF7 A;  2W2Q E;  3V65 B;  1L5G B;  1QFK L;  3IJE B;  4ZXY L;  3GCW E;  1IVO C;  4D0E A;  1EZQ B;  4Y7A B;  1TPG A;  5L2Y L;  1FAX L;  3OLT A;  1HAF A;  1ATA A;  2BQW A;  2P3F L;  3SOQ A;  2XBV L;  2Y38 A;  2KV4 A;  1YGC L;  3RR3 A;  1NFY B;  2KNI A;  2K2T A;  4O1Z A;  5IKT A;  4YT6 L;  1EGF A;  1UZJ A;  1NT0 A;  1IQH L;  1J9C L;  3FBY A;  1HAE A;  3BT2 A;  5K0H B;  2Y7X B;  1N7D A;  3F6U L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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