2P4DA

Structure-assisted discovery of variola major h1 phosphatase inhibitors
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
163
structure length
163
Chain Sequence
SLYKYLLLRSTGDMRRAKSPTIMTRVTNNVYLGNYKNAMNAPSSEVKFKYVLNLTMDKYTLPNSNINIIHIPLVDDTTTDISKYFDDVTAFLSKCDQRNEPVLVHCVAGVNRSGAMILAYLMSKNKESSPMLYFLYVYHSMRDLRGAFVENPSFKRQIIEKYV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-assisted discovery of variola major H1 phosphatase inhibitors
pubmed doi rcsb
molecule tags Hydrolase
source organism Variola virus
molecule keywords Dual specificity protein phosphatase
total genus 57
structure length 163
sequence length 163
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2007-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00782 DSPc Dual specificity phosphatase, catalytic domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2p4dA00
1YTSA 1G4WR 1Q6MA 1ECVA 3EAXA 3H2XA 3QKQA 4WTYA 3OMHA 1LYVA 1X24A 1ONZA 1RPMA 2BGDA 4JBCA 3RGOA 2IMGA 4S0GA 2B4PA 2F70A 1JF7A 2GWOA 2H04A 1U26A 1YGRA 3D44A 3AWFA 4OHIA 1Q6NA 5AWXA 2I4HA 3I7ZA 4I8NA 3ZM1A 1C86A 2VEWA 3O3LA 4WU3A 1L8GA 2CNGA 1L8KA 5KA4A 1A5YA 3PS5A 3S3EA 5KACA 4RHGA 1NL9A 2CM7A 2QBRA 4YAAA 2QCJA 2J17A 1GFYA 2QEPA 2H4KA 2H4VA 2C7SA 2PBNA 3QCHA 4ICZA 4RDDA 2Y2FA 1OESA 1G7GA 4H34A 4QBWA 4R0SA 3O4TA 3EU0A 2OC3A 1U24A 2F46A 2QDCA 3B7OA 1VHRA 3V0HA 5KA0A 2QBPA 1YTNA 2B4OA 2HC1A 1AAXA 3O5XA 1M3GA 4KYRA 3F9BA 4QBEA 2F6ZA 2I6MA 5BUGA 1T48A 5MMZB 3MMJA 2ZN7A 3ZMPA 2VEYA 5KADA 3QCJA 4WU2A 2HCMA 2P4DA 1C83A 1PTVA 1NWLA 3BRHA 4GS0A 5I6VA 2SHPA 1MKPA 2H03A 5K22A 3N0AA 1OEUA 5KA9A 4GRZA 2A3KA 1C88A 1NZ7A 2B07A 3O4SA 2QBQA 2FJMA 3D1OA 3QCEA 2I6JA 5IBSA 3SR9A 1G1FA 5KA8A 3RZ2A 4GRYA 2M3VA 1YFOA 2I6PA 3D9CA 4OHHA 5GTJA 2F6FA 3F9AA 4NWFA 2CJZA 2FJNA 4JMJA 3GXHA 5K25A 4TVVA 1XRIA 1G4US 2CMCA 3S3FA 1Q6JA 3F41A 3QCBA 4J51A 2ESBA 1LQFA 4DGXA 2Q05A 3RO1A 2BGEA 5K24A 2HY3A 2OOQA 5EHPA 4QUMA 2G6ZA 1R6HA 3OLRA 1WRMA 3RGQA 4DGPA 2J16A 5LXQB 2P6XA 1PXHA 1I9SA 2I75A 3QCKA 4QAPA 1QZ0A 4QAHA 1J4XA 2HXPA 3EB1A 2GP0A 3MOWA 1FPZA 1PA1A 3V0EA 4Z6BA 2CNIA 3AWEA 1OETA 1ZCLA 4RI5A 1YGUA 1NNYA 1ZZWA 5KA7A 3A5KA 3QCNA 3F99A 2F6YA 2J16B 3EMUA 4JMKA 2H02A 1BZHA 4IKCA 1D5RA 2G59A 4H1OA 1PH0A 2B49A 2HB1A 2F6WA 3BM8A 1LARA 4ZI4A 4B04A 1C87A 3I36A 1XXVA 2H4GA 3QKPA 2PQ5A 2I6IA 1ZCKA 1NO6A 3ZM0A 2CM3A 5KA2A 5K9VA 3CM3A 2QDMA 1SUGA 3A5JA 4RH9A 1Q1MA 2DXPA 1G1HA 4GE2A 4KYQA 2OUDA 5K9WA 4QUNA 5KA3A 2CNHA 1WCHA 3QCIA 2WGPA 3S3KA 4GE6A 2ZMMA 3GXGA 5KAAA 1P15A 1OEOX 2VEUA 2NT2A 1JLNA 3S3HA 4NNDA 5BZXA 3CWEA 4GFUA 4Y2EA 1KAVA 1PTYA 5IBMA 3MOZA 4OHEA 2CNFA 1OEVA 4WOHA 2JJDA 4OHDA 2QBSA 5BX1A 3ZM2A 2Y96A 1WAXA 4ZRTA 2RF6A 2PSZA 2CMBA 1FQ1A 2B3OA 2NV5A 1C85A 1XXPA 3ZM3A 2E0TA 4AZ1A 1PTTA 4NX8A 1XM2A 4KI9A 2HNQA 3S4EA 1EEOA 1Q6PA 3AWGA 4RKKA 3BLUA 3QCGA 4BPCA 1YZ4A 2QDPA 5K23A 4OHLA 2BIJA 5BZZA 2Q47A 3BLTA 4PYHA 1T4JA 1ZC0A 3QCDA 2NT7A 2I1YA 2I42A 2FH7A 4JNBA 1YN9A 2A8BA 4ZN5A 2OZ5A 1RXDA 2HVLA 2B4SA 2MBCA 2BV5A 1V3AA 1EENA 3I80A 4HJQA 1G7FA 2AZRA 1YPTA 1I57A 2AHSA 1YWFA 4GFVA 3QCCA 2F6TA 2NLKA 1BZCA 1PTUA 2CM2A 2CFVA 5HDEA 3D1HA 2PA5A 2R0BA 4D3PA 2I4GA 1XBOA 3V0DA 2VEXA 4BJOA 2C46A 1PA9A 2F71A 3ZV2A 3V0JA 3SMEA 4GE5A 2PI7A 5EHRA 2HC2A 3QCMA 4ERCA 4YR8B 2B4UA 1NWEA 1OEMX 2CNEA 4NYHA 2I6OA 4D3QA 1OHEA 2I3RA 3D1QA 1I9TA 2NZ6A 2GJTA 5KABA 2HNPA 3V0IA 1G1GA 1GWZA 1T49A 1ONYA 3ZMQA 1FPRA 2F6VA 2YDUA 2I4EA 3V0FA 4D3RA 2PT0A 5J8RA 3EZZA 3O4UA 1KAKA 4RH5A 3V0GA 3M4UA 4NWGA 1OHDA 3F81A 4R0TA 4HJPA 1Q6SA 4GWFA 1QXKA 2I5XA 2BZLA 5KA1A 2NTAA 1Q6TA 4MBBA 1YTWA 4Y14A 2I3UA 3S4OA 2QCTA 1C84A 1PYNA 4HRFA 4R30A 3QCLA 3LJ8A 1U25A 3D42A 3NMEA 2CMAA 2VEVA 5M43A 4PVGA 1BZJA 3U96A 4RI4A 2CM8A 3QCFA 1OHCA
chains in the Genus database with same CATH superfamily
1YTSA 1G4WR 1Q6MA 1ECVA 3EAXA 3H2XA 3QKQA 4WTYA 3OMHA 1LYVA 1X24A 1ONZA 1RPMA 2BGDA 1O5ZA 4JBCA 1E8CA 3RGOA 2IMGA 4S0GA 2B4PA 2F70A 1JF7A 2GWOA 2H04A 1W78A 1U26A 1YGRA 3D44A 3AWFA 4OHIA 1Q6NA 5AWXA 2I4HA 3I7ZA 4UAGA 4CVMA 4I8NA 3ZM1A 1C86A 2VEWA 3O3LA 4WU3A 1L8GA 1J6UA 2CNGA 1L8KA 5KA4A 1A5YA 3PS5A 3S3EA 2JFGA 5KACA 4RHGA 1NL9A 2CM7A 2QBRA 4YAAA 2QCJA 2J17A 1GFYA 2QEPA 2H4KA 3NRSA 2H4VA 2C7SA 2PBNA 3QCHA 4ICZA 4RDDA 2Y2FA 1OESA 1G7GA 4H34A 4QBWA 4R0SA 3O4TA 3EU0A 2OC3A 1U24A 2F46A 2QDCA 2VTEA 3B7OA 1VHRA 3V0HA 1GQQA 5KA0A 2XJAA 2QBPA 1YTNA 1UAGA 2B4OA 2HC1A 1AAXA 3O5XA 1M3GA 4KYRA 3F9BA 4QBEA 2F6ZA 2I6MA 5BUGA 1T48A 5MMZB 3MMJA 2ZN7A 3ZMPA 2VEYA 5KADA 3QCJA 4WU2A 2HCMA 2F00A 2P4DA 1C83A 1PTVA 1NWLA 3BRHA 4GS0A 3ZM5A 5I6VA 2SHPA 1MKPA 2H03A 5K22A 2Y66A 3N0AA 5A5EA 1OEUA 5KA9A 4GRZA 2A3KA 1C88A 1NZ7A 2B07A 3O4SA 2QBQA 2FJMA 3D1OA 3QCEA 2I6JA 2GC6A 5IBSA 3SR9A 1W7KA 1G1FA 5KA8A 3RZ2A 4GRYA 2M3VA 1YFOA 2I6PA 3D9CA 4OHHA 5GTJA 4C13A 2F6FA 3F9AA 4BUBA 4NWFA 2CJZA 2FJNA 4JMJA 3GXHA 5K25A 4TVVA 1XRIA 1G4US 2CMCA 3S3FA 1Q6JA 3F41A 3QCBA 4J51A 2ESBA 4CVLA 1LQFA 4DGXA 3ZM6A 2Q05A 3RO1A 2BGEA 5K24A 2HY3A 2OOQA 5EHPA 4QUMA 2G6ZA 1R6HA 3OLRA 1WRMA 1FGSA 3RGQA 4DGPA 2J16A 3UAGA 2P6XA 1PXHA 5LXQB 1I9SA 2I75A 3QCKA 4QAPA 1QZ0A 4QAHA 1J4XA 2HXPA 3EB1A 2GP0A 3MOWA 1FPZA 1PA1A 3V0EA 4Z6BA 2CNIA 2JFHA 3AWEA 1OETA 1ZCLA 4RI5A 1YGUA 1NNYA 1ZZWA 5KA7A 3A5KA 3QCNA 3F99A 2F6YA 2J16B 3EMUA 4JMKA 2H02A 1BZHA 4C12A 4IKCA 1D5RA 2G59A 4H1OA 4HV4A 1PH0A 2B49A 3BM8A 2WTZA 2HB1A 2F6WA 2VORA 2WJPA 1LARA 4ZI4A 2GC5A 4B04A 1C87A 3I36A 1XXVA 2H4GA 3QKPA 2PQ5A 2I6IA 1ZCKA 1NO6A 3ZM0A 2CM3A 5KA2A 5K9VA 3MVNA 1EEHA 3CM3A 2QDMA 1SUGA 3A5JA 3LK7A 4RH9A 1Q1MA 2DXPA 1G1HA 4GE2A 4KYQA 2OUDA 5K9WA 4QUNA 5KA3A 2Y68A 2CNHA 1WCHA 3QCIA 2WGPA 3S3KA 4GE6A 4ZIYA 2ZMMA 3GXGA 5KAAA 1P15A 1OEOX 2VEUA 2NT2A 1JLNA 3S3HA 4NNDA 5BZXA 3CWEA 4GFUA 4Y2EA 1KAVA 1PTYA 2JFFA 5IBMA 3MOZA 4OHEA 2CNFA 1OEVA 4WOHA 2JJDA 4QDIA 4OHDA 2QBSA 5BX1A 3ZM2A 2Y96A 3N2AA 1WAXA 2AM1A 2GCAA 4ZRTA 2RF6A 2PSZA 2VOSA 2CMBA 1FQ1A 2B3OA 2NV5A 1C85A 1XXPA 3ZM3A 2E0TA 4AZ1A 1PTTA 4NX8A 4QF5A 1XM2A 4KI9A 2HNQA 3S4EA 1EEOA 1Q6PA 2VTDA 3AWGA 4RKKA 3BLUA 3QCGA 4BPCA 1YZ4A 2QDPA 5K23A 4OHLA 2Y1OA 2BIJA 5BZZA 2Q47A 2UUOA 1JBVA 3BLTA 4PYHA 1T4JA 1ZC0A 3QCDA 2Y67A 2NT7A 2I1YA 2I42A 2FH7A 4JNBA 1YN9A 2A8BA 4ZN5A 2OZ5A 2UUPA 1RXDA 2HVLA 2B4SA 2MBCA 3ZL8A 1P3DA 2BV5A 1V3AA 1P31A 1EENA 3I80A 4HJQA 1G7FA 2AZRA 1E0DA 1YPTA 1I57A 2AHSA 1YWFA 4GFVA 3QCCA 2F6TA 2NLKA 1BZCA 1PTUA 2CM2A 3HN7A 2CFVA 5HDEA 3D1HA 2PA5A 2R0BA 4D3PA 2I4GA 1XBOA 3V0DA 2VEXA 4BJOA 2C46A 1PA9A 2F71A 3ZV2A 3V0JA 4CVKA 2XPCA 1JBWA 2AM2A 3SMEA 4GE5A 2PI7A 5EHRA 2HC2A 3QCMA 4ERCA 4YR8B 3QCZA 2B4UA 1NWEA 1OEMX 2CNEA 4NYHA 2I6OA 4D3QA 1OHEA 2I3RA 3D1QA 1I9TA 2NZ6A 2GJTA 5KABA 2HNPA 3V0IA 1G1GA 1GWZA 1T49A 1ONYA 3ZMQA 1FPRA 2F6VA 2YDUA 2I4EA 3V0FA 4D3RA 2PT0A 5J8RA 3EZZA 3O4UA 1KAKA 4RH5A 3V0GA 3M4UA 4NWGA 2UAGA 1OHDA 3F81A 4R0TA 4HJPA 1Q6SA 4GWFA 1QXKA 2I5XA 2BZLA 5KA1A 2NTAA 1Q6TA 1GQYA 4MBBA 1YTWA 4Y14A 2I3UA 3S4OA 2GCBA 2QCTA 1C84A 1PYNA 4HRFA 4R30A 4BUCA 3QCLA 3LJ8A 1U25A 3D42A 3NMEA 2CMAA 2VEVA 5M43A 4PVGA 1BZJA 3U96A 4RI4A 3PYZA 2CM8A 3QCFA 5A5FA 1OHCA 1GG4A 2X5OA
chains in the Genus database with same CATH topology
1YTSA 1G4WR 1Q6MA 1ECVA 3EAXA 3H2XA 3QKQA 4WTYA 3OMHA 1LYVA 1X24A 1ONZA 1RPMA 2BGDA 4JBCA 3RGOA 2IMGA 4S0GA 2B4PA 2F70A 1JF7A 2GWOA 2H04A 1U26A 1YGRA 3D44A 3AWFA 4OHIA 1Q6NA 5AWXA 2I4HA 3I7ZA 4I8NA 3ZM1A 1C86A 2VEWA 3O3LA 4WU3A 1L8GA 2CNGA 1L8KA 5KA4A 1A5YA 3PS5A 3S3EA 5KACA 4RHGA 1NL9A 2CM7A 2QBRA 4YAAA 2QCJA 2J17A 1GFYA 2QEPA 2H4KA 2H4VA 2C7SA 2PBNA 3QCHA 4ICZA 4RDDA 2Y2FA 1OESA 1G7GA 4H34A 4QBWA 4R0SA 3O4TA 3EU0A 2OC3A 1U24A 2F46A 2QDCA 3B7OA 1VHRA 3V0HA 5KA0A 2QBPA 1YTNA 2B4OA 2HC1A 1AAXA 3O5XA 1M3GA 4KYRA 3F9BA 4QBEA 2F6ZA 2I6MA 5BUGA 1T48A 5MMZB 3MMJA 2ZN7A 3ZMPA 2VEYA 5KADA 3QCJA 4WU2A 2HCMA 2P4DA 1C83A 1PTVA 1NWLA 3BRHA 4GS0A 5I6VA 2SHPA 1MKPA 2H03A 5K22A 3N0AA 1OEUA 5KA9A 4GRZA 2A3KA 1C88A 1NZ7A 2B07A 3O4SA 2QBQA 2FJMA 3D1OA 3QCEA 2I6JA 5IBSA 3SR9A 1G1FA 5KA8A 3RZ2A 4GRYA 2M3VA 1YFOA 2I6PA 3D9CA 4OHHA 5GTJA 2F6FA 3F9AA 4NWFA 2CJZA 2FJNA 4JMJA 3GXHA 5K25A 4TVVA 1XRIA 1G4US 2CMCA 3S3FA 1Q6JA 3F41A 3QCBA 4J51A 2ESBA 1LQFA 4DGXA 2Q05A 3RO1A 2BGEA 5K24A 2HY3A 2OOQA 5EHPA 4QUMA 2G6ZA 1R6HA 3OLRA 1WRMA 3RGQA 4DGPA 2J16A 5LXQB 2P6XA 1PXHA 1I9SA 2I75A 3QCKA 4QAPA 1QZ0A 4QAHA 1J4XA 2HXPA 3EB1A 2GP0A 3MOWA 1FPZA 1PA1A 3V0EA 4Z6BA 2CNIA 3AWEA 1OETA 1ZCLA 4RI5A 1YGUA 1NNYA 1ZZWA 5KA7A 3A5KA 3QCNA 3F99A 2F6YA 2J16B 3EMUA 4JMKA 2H02A 1BZHA 4IKCA 1D5RA 2G59A 4H1OA 1PH0A 2B49A 2HB1A 2F6WA 3BM8A 1LARA 4ZI4A 4B04A 1C87A 3I36A 1XXVA 2H4GA 3QKPA 2PQ5A 2I6IA 1ZCKA 1NO6A 3ZM0A 2CM3A 5KA2A 5K9VA 3CM3A 2QDMA 1SUGA 3A5JA 4RH9A 1Q1MA 2DXPA 1G1HA 4GE2A 4KYQA 2OUDA 5K9WA 4QUNA 5KA3A 2CNHA 1WCHA 3QCIA 2WGPA 3S3KA 4GE6A 2ZMMA 3GXGA 5KAAA 1P15A 1OEOX 2VEUA 2NT2A 1JLNA 3S3HA 4NNDA 5BZXA 3CWEA 4GFUA 4Y2EA 1KAVA 1PTYA 5IBMA 3MOZA 4OHEA 2CNFA 1OEVA 4WOHA 2JJDA 4OHDA 2QBSA 5BX1A 3ZM2A 2Y96A 1WAXA 4ZRTA 2RF6A 2PSZA 2CMBA 1FQ1A 2B3OA 2NV5A 1C85A 1XXPA 3ZM3A 2E0TA 4AZ1A 1PTTA 4NX8A 1XM2A 4KI9A 2HNQA 3S4EA 1EEOA 1Q6PA 3AWGA 4RKKA 3BLUA 3QCGA 4BPCA 1YZ4A 2QDPA 5K23A 4OHLA 2BIJA 5BZZA 2Q47A 3BLTA 4PYHA 1T4JA 1ZC0A 3QCDA 2NT7A 2I1YA 2I42A 2FH7A 4JNBA 1YN9A 2A8BA 4ZN5A 2OZ5A 1RXDA 2HVLA 2B4SA 2MBCA 2BV5A 1V3AA 1EENA 3I80A 4HJQA 1G7FA 2AZRA 1YPTA 1I57A 2AHSA 1YWFA 4GFVA 3QCCA 2F6TA 2NLKA 1BZCA 1PTUA 2CM2A 2CFVA 5HDEA 3D1HA 2PA5A 2R0BA 4D3PA 2I4GA 1XBOA 3V0DA 2VEXA 4BJOA 2C46A 1PA9A 2F71A 3ZV2A 3V0JA 3SMEA 4GE5A 2PI7A 5EHRA 2HC2A 3QCMA 4ERCA 4YR8B 2B4UA 1NWEA 1OEMX 2CNEA 4NYHA 2I6OA 4D3QA 1OHEA 2I3RA 3D1QA 1I9TA 2NZ6A 2GJTA 5KABA 2HNPA 3V0IA 1G1GA 1GWZA 1T49A 1ONYA 3ZMQA 1FPRA 2F6VA 2YDUA 2I4EA 3V0FA 4D3RA 2PT0A 5J8RA 3EZZA 3O4UA 1KAKA 4RH5A 3V0GA 3M4UA 4NWGA 1OHDA 3F81A 4R0TA 4HJPA 1Q6SA 4GWFA 1QXKA 2I5XA 2BZLA 5KA1A 2NTAA 1Q6TA 4MBBA 1YTWA 4Y14A 2I3UA 3S4OA 2QCTA 1C84A 1PYNA 4HRFA 4R30A 3QCLA 3LJ8A 1U25A 3D42A 3NMEA 2CMAA 2VEVA 5M43A 4PVGA 1BZJA 3U96A 4RI4A 2CM8A 3QCFA 1OHCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YTS A;  1G4W R;  1Q6M A;  1ECV A;  3EAX A;  3H2X A;  3QKQ A;  4WTY A;  3OMH A;  1LYV A;  1X24 A;  1ONZ A;  1RPM A;  2BGD A;  4JBC A;  3RGO A;  2IMG A;  4S0G A;  2B4P A;  2F70 A;  1JF7 A;  2GWO A;  2H04 A;  1U26 A;  1YGR A;  3D44 A;  3AWF A;  4OHI A;  1Q6N A;  5AWX A;  2I4H A;  3I7Z A;  4I8N A;  3ZM1 A;  1C86 A;  2VEW A;  3O3L A;  4WU3 A;  1L8G A;  2CNG A;  1L8K A;  5KA4 A;  1A5Y A;  3PS5 A;  3S3E A;  5KAC A;  4RHG A;  1NL9 A;  2CM7 A;  2QBR A;  4YAA A;  2QCJ A;  2J17 A;  1GFY A;  2QEP A;  2H4K A;  2H4V A;  2C7S A;  2PBN A;  3QCH A;  4ICZ A;  4RDD A;  2Y2F A;  1OES A;  1G7G A;  4H34 A;  4QBW A;  4R0S A;  3O4T A;  3EU0 A;  2OC3 A;  1U24 A;  2F46 A;  2QDC A;  3B7O A;  1VHR A;  3V0H A;  5KA0 A;  2QBP A;  1YTN A;  2B4O A;  2HC1 A;  1AAX A;  3O5X A;  1M3G A;  4KYR A;  3F9B A;  4QBE A;  2F6Z A;  2I6M A;  5BUG A;  1T48 A;  5MMZ B;  3MMJ A;  2ZN7 A;  3ZMP A;  2VEY A;  5KAD A;  3QCJ A;  4WU2 A;  2HCM A;  2P4D A;  1C83 A;  1PTV A;  1NWL A;  3BRH A;  4GS0 A;  5I6V A;  2SHP A;  1MKP A;  2H03 A;  5K22 A;  3N0A A;  1OEU A;  5KA9 A;  4GRZ A;  2A3K A;  1C88 A;  1NZ7 A;  2B07 A;  3O4S A;  2QBQ A;  2FJM A;  3D1O A;  3QCE A;  2I6J A;  5IBS A;  3SR9 A;  1G1F A;  5KA8 A;  3RZ2 A;  4GRY A;  2M3V A;  1YFO A;  2I6P A;  3D9C A;  4OHH A;  5GTJ A;  2F6F A;  3F9A A;  4NWF A;  2CJZ A;  2FJN A;  4JMJ A;  3GXH A;  5K25 A;  4TVV A;  1XRI A;  1G4U S;  2CMC A;  3S3F A;  1Q6J A;  3F41 A;  3QCB A;  4J51 A;  2ESB A;  1LQF A;  4DGX A;  2Q05 A;  3RO1 A;  2BGE A;  5K24 A;  2HY3 A;  2OOQ A;  5EHP A;  4QUM A;  2G6Z A;  1R6H A;  3OLR A;  1WRM A;  3RGQ A;  4DGP A;  2J16 A;  5LXQ B;  2P6X A;  1PXH A;  1I9S A;  2I75 A;  3QCK A;  4QAP A;  1QZ0 A;  4QAH A;  1J4X A;  2HXP A;  3EB1 A;  2GP0 A;  3MOW A;  1FPZ A;  1PA1 A;  3V0E A;  4Z6B A;  2CNI A;  3AWE A;  1OET A;  1ZCL A;  4RI5 A;  1YGU A;  1NNY A;  1ZZW A;  5KA7 A;  3A5K A;  3QCN A;  3F99 A;  2F6Y A;  2J16 B;  3EMU A;  4JMK A;  2H02 A;  1BZH A;  4IKC A;  1D5R A;  2G59 A;  4H1O A;  1PH0 A;  2B49 A;  2HB1 A;  2F6W A;  3BM8 A;  1LAR A;  4ZI4 A;  4B04 A;  1C87 A;  3I36 A;  1XXV A;  2H4G A;  3QKP A;  2PQ5 A;  2I6I A;  1ZCK A;  1NO6 A;  3ZM0 A;  2CM3 A;  5KA2 A;  5K9V A;  3CM3 A;  2QDM A;  1SUG A;  3A5J A;  4RH9 A;  1Q1M A;  2DXP A;  1G1H A;  4GE2 A;  4KYQ A;  2OUD A;  5K9W A;  4QUN A;  5KA3 A;  2CNH A;  1WCH A;  3QCI A;  2WGP A;  3S3K A;  4GE6 A;  2ZMM A;  3GXG A;  5KAA A;  1P15 A;  1OEO X;  2VEU A;  2NT2 A;  1JLN A;  3S3H A;  4NND A;  5BZX A;  3CWE A;  4GFU A;  4Y2E A;  1KAV A;  1PTY A;  5IBM A;  3MOZ A;  4OHE A;  2CNF A;  1OEV A;  4WOH A;  2JJD A;  4OHD A;  2QBS A;  5BX1 A;  3ZM2 A;  2Y96 A;  1WAX A;  4ZRT A;  2RF6 A;  2PSZ A;  2CMB A;  1FQ1 A;  2B3O A;  2NV5 A;  1C85 A;  1XXP A;  3ZM3 A;  2E0T A;  4AZ1 A;  1PTT A;  4NX8 A;  1XM2 A;  4KI9 A;  2HNQ A;  3S4E A;  1EEO A;  1Q6P A;  3AWG A;  4RKK A;  3BLU A;  3QCG A;  4BPC A;  1YZ4 A;  2QDP A;  5K23 A;  4OHL A;  2BIJ A;  5BZZ A;  2Q47 A;  3BLT A;  4PYH A;  1T4J A;  1ZC0 A;  3QCD A;  2NT7 A;  2I1Y A;  2I42 A;  2FH7 A;  4JNB A;  1YN9 A;  2A8B A;  4ZN5 A;  2OZ5 A;  1RXD A;  2HVL A;  2B4S A;  2MBC A;  2BV5 A;  1V3A A;  1EEN A;  3I80 A;  4HJQ A;  1G7F A;  2AZR A;  1YPT A;  1I57 A;  2AHS A;  1YWF A;  4GFV A;  3QCC A;  2F6T A;  2NLK A;  1BZC A;  1PTU A;  2CM2 A;  2CFV A;  5HDE A;  3D1H A;  2PA5 A;  2R0B A;  4D3P A;  2I4G A;  1XBO A;  3V0D A;  2VEX A;  4BJO A;  2C46 A;  1PA9 A;  2F71 A;  3ZV2 A;  3V0J A;  3SME A;  4GE5 A;  2PI7 A;  5EHR A;  2HC2 A;  3QCM A;  4ERC A;  4YR8 B;  2B4U A;  1NWE A;  1OEM X;  2CNE A;  4NYH A;  2I6O A;  4D3Q A;  1OHE A;  2I3R A;  3D1Q A;  1I9T A;  2NZ6 A;  2GJT A;  5KAB A;  2HNP A;  3V0I A;  1G1G A;  1GWZ A;  1T49 A;  1ONY A;  3ZMQ A;  1FPR A;  2F6V A;  2YDU A;  2I4E A;  3V0F A;  4D3R A;  2PT0 A;  5J8R A;  3EZZ A;  3O4U A;  1KAK A;  4RH5 A;  3V0G A;  3M4U A;  4NWG A;  1OHD A;  3F81 A;  4R0T A;  4HJP A;  1Q6S A;  4GWF A;  1QXK A;  2I5X A;  2BZL A;  5KA1 A;  2NTA A;  1Q6T A;  4MBB A;  1YTW A;  4Y14 A;  2I3U A;  3S4O A;  2QCT A;  1C84 A;  1PYN A;  4HRF A;  4R30 A;  3QCL A;  3LJ8 A;  1U25 A;  3D42 A;  3NME A;  2CMA A;  2VEV A;  5M43 A;  4PVG A;  1BZJ A;  3U96 A;  4RI4 A;  2CM8 A;  3QCF A;  1OHC A; 
#chains in the Genus database with same CATH topology
 1YTS A;  1G4W R;  1Q6M A;  1ECV A;  3EAX A;  3H2X A;  3QKQ A;  4WTY A;  3OMH A;  1LYV A;  1X24 A;  1ONZ A;  1RPM A;  2BGD A;  1O5Z A;  4JBC A;  1E8C A;  3RGO A;  2IMG A;  4S0G A;  2B4P A;  2F70 A;  1JF7 A;  2GWO A;  2H04 A;  1W78 A;  1U26 A;  1YGR A;  3D44 A;  3AWF A;  4OHI A;  1Q6N A;  5AWX A;  2I4H A;  3I7Z A;  4UAG A;  4CVM A;  4I8N A;  3ZM1 A;  1C86 A;  2VEW A;  3O3L A;  4WU3 A;  1L8G A;  1J6U A;  2CNG A;  1L8K A;  5KA4 A;  1A5Y A;  3PS5 A;  3S3E A;  2JFG A;  5KAC A;  4RHG A;  1NL9 A;  2CM7 A;  2QBR A;  4YAA A;  2QCJ A;  2J17 A;  1GFY A;  2QEP A;  2H4K A;  3NRS A;  2H4V A;  2C7S A;  2PBN A;  3QCH A;  4ICZ A;  4RDD A;  2Y2F A;  1OES A;  1G7G A;  4H34 A;  4QBW A;  4R0S A;  3O4T A;  3EU0 A;  2OC3 A;  1U24 A;  2F46 A;  2QDC A;  2VTE A;  3B7O A;  1VHR A;  3V0H A;  1GQQ A;  5KA0 A;  2XJA A;  2QBP A;  1YTN A;  1UAG A;  2B4O A;  2HC1 A;  1AAX A;  3O5X A;  1M3G A;  4KYR A;  3F9B A;  4QBE A;  2F6Z A;  2I6M A;  5BUG A;  1T48 A;  5MMZ B;  3MMJ A;  2ZN7 A;  3ZMP A;  2VEY A;  5KAD A;  3QCJ A;  4WU2 A;  2HCM A;  2F00 A;  2P4D A;  1C83 A;  1PTV A;  1NWL A;  3BRH A;  4GS0 A;  3ZM5 A;  5I6V A;  2SHP A;  1MKP A;  2H03 A;  5K22 A;  2Y66 A;  3N0A A;  5A5E A;  1OEU A;  5KA9 A;  4GRZ A;  2A3K A;  1C88 A;  1NZ7 A;  2B07 A;  3O4S A;  2QBQ A;  2FJM A;  3D1O A;  3QCE A;  2I6J A;  2GC6 A;  5IBS A;  3SR9 A;  1W7K A;  1G1F A;  5KA8 A;  3RZ2 A;  4GRY A;  2M3V A;  1YFO A;  2I6P A;  3D9C A;  4OHH A;  5GTJ A;  4C13 A;  2F6F A;  3F9A A;  4BUB A;  4NWF A;  2CJZ A;  2FJN A;  4JMJ A;  3GXH A;  5K25 A;  4TVV A;  1XRI A;  1G4U S;  2CMC A;  3S3F A;  1Q6J A;  3F41 A;  3QCB A;  4J51 A;  2ESB A;  4CVL A;  1LQF A;  4DGX A;  3ZM6 A;  2Q05 A;  3RO1 A;  2BGE A;  5K24 A;  2HY3 A;  2OOQ A;  5EHP A;  4QUM A;  2G6Z A;  1R6H A;  3OLR A;  1WRM A;  1FGS A;  3RGQ A;  4DGP A;  2J16 A;  3UAG A;  2P6X A;  1PXH A;  5LXQ B;  1I9S A;  2I75 A;  3QCK A;  4QAP A;  1QZ0 A;  4QAH A;  1J4X A;  2HXP A;  3EB1 A;  2GP0 A;  3MOW A;  1FPZ A;  1PA1 A;  3V0E A;  4Z6B A;  2CNI A;  2JFH A;  3AWE A;  1OET A;  1ZCL A;  4RI5 A;  1YGU A;  1NNY A;  1ZZW A;  5KA7 A;  3A5K A;  3QCN A;  3F99 A;  2F6Y A;  2J16 B;  3EMU A;  4JMK A;  2H02 A;  1BZH A;  4C12 A;  4IKC A;  1D5R A;  2G59 A;  4H1O A;  4HV4 A;  1PH0 A;  2B49 A;  3BM8 A;  2WTZ A;  2HB1 A;  2F6W A;  2VOR A;  2WJP A;  1LAR A;  4ZI4 A;  2GC5 A;  4B04 A;  1C87 A;  3I36 A;  1XXV A;  2H4G A;  3QKP A;  2PQ5 A;  2I6I A;  1ZCK A;  1NO6 A;  3ZM0 A;  2CM3 A;  5KA2 A;  5K9V A;  3MVN A;  1EEH A;  3CM3 A;  2QDM A;  1SUG A;  3A5J A;  3LK7 A;  4RH9 A;  1Q1M A;  2DXP A;  1G1H A;  4GE2 A;  4KYQ A;  2OUD A;  5K9W A;  4QUN A;  5KA3 A;  2Y68 A;  2CNH A;  1WCH A;  3QCI A;  2WGP A;  3S3K A;  4GE6 A;  4ZIY A;  2ZMM A;  3GXG A;  5KAA A;  1P15 A;  1OEO X;  2VEU A;  2NT2 A;  1JLN A;  3S3H A;  4NND A;  5BZX A;  3CWE A;  4GFU A;  4Y2E A;  1KAV A;  1PTY A;  2JFF A;  5IBM A;  3MOZ A;  4OHE A;  2CNF A;  1OEV A;  4WOH A;  2JJD A;  4QDI A;  4OHD A;  2QBS A;  5BX1 A;  3ZM2 A;  2Y96 A;  3N2A A;  1WAX A;  2AM1 A;  2GCA A;  4ZRT A;  2RF6 A;  2PSZ A;  2VOS A;  2CMB A;  1FQ1 A;  2B3O A;  2NV5 A;  1C85 A;  1XXP A;  3ZM3 A;  2E0T A;  4AZ1 A;  1PTT A;  4NX8 A;  4QF5 A;  1XM2 A;  4KI9 A;  2HNQ A;  3S4E A;  1EEO A;  1Q6P A;  2VTD A;  3AWG A;  4RKK A;  3BLU A;  3QCG A;  4BPC A;  1YZ4 A;  2QDP A;  5K23 A;  4OHL A;  2Y1O A;  2BIJ A;  5BZZ A;  2Q47 A;  2UUO A;  1JBV A;  3BLT A;  4PYH A;  1T4J A;  1ZC0 A;  3QCD A;  2Y67 A;  2NT7 A;  2I1Y A;  2I42 A;  2FH7 A;  4JNB A;  1YN9 A;  2A8B A;  4ZN5 A;  2OZ5 A;  2UUP A;  1RXD A;  2HVL A;  2B4S A;  2MBC A;  3ZL8 A;  1P3D A;  2BV5 A;  1V3A A;  1P31 A;  1EEN A;  3I80 A;  4HJQ A;  1G7F A;  2AZR A;  1E0D A;  1YPT A;  1I57 A;  2AHS A;  1YWF A;  4GFV A;  3QCC A;  2F6T A;  2NLK A;  1BZC A;  1PTU A;  2CM2 A;  3HN7 A;  2CFV A;  5HDE A;  3D1H A;  2PA5 A;  2R0B A;  4D3P A;  2I4G A;  1XBO A;  3V0D A;  2VEX A;  4BJO A;  2C46 A;  1PA9 A;  2F71 A;  3ZV2 A;  3V0J A;  4CVK A;  2XPC A;  1JBW A;  2AM2 A;  3SME A;  4GE5 A;  2PI7 A;  5EHR A;  2HC2 A;  3QCM A;  4ERC A;  4YR8 B;  3QCZ A;  2B4U A;  1NWE A;  1OEM X;  2CNE A;  4NYH A;  2I6O A;  4D3Q A;  1OHE A;  2I3R A;  3D1Q A;  1I9T A;  2NZ6 A;  2GJT A;  5KAB A;  2HNP A;  3V0I A;  1G1G A;  1GWZ A;  1T49 A;  1ONY A;  3ZMQ A;  1FPR A;  2F6V A;  2YDU A;  2I4E A;  3V0F A;  4D3R A;  2PT0 A;  5J8R A;  3EZZ A;  3O4U A;  1KAK A;  4RH5 A;  3V0G A;  3M4U A;  4NWG A;  2UAG A;  1OHD A;  3F81 A;  4R0T A;  4HJP A;  1Q6S A;  4GWF A;  1QXK A;  2I5X A;  2BZL A;  5KA1 A;  2NTA A;  1Q6T A;  1GQY A;  4MBB A;  1YTW A;  4Y14 A;  2I3U A;  3S4O A;  2GCB A;  2QCT A;  1C84 A;  1PYN A;  4HRF A;  4R30 A;  4BUC A;  3QCL A;  3LJ8 A;  1U25 A;  3D42 A;  3NME A;  2CMA A;  2VEV A;  5M43 A;  4PVG A;  1BZJ A;  3U96 A;  4RI4 A;  3PYZ A;  2CM8 A;  3QCF A;  5A5F A;  1OHC A;  1GG4 A;  2X5O A; 
#chains in the Genus database with same CATH homology
 1YTS A;  1G4W R;  1Q6M A;  1ECV A;  3EAX A;  3H2X A;  3QKQ A;  4WTY A;  3OMH A;  1LYV A;  1X24 A;  1ONZ A;  1RPM A;  2BGD A;  4JBC A;  3RGO A;  2IMG A;  4S0G A;  2B4P A;  2F70 A;  1JF7 A;  2GWO A;  2H04 A;  1U26 A;  1YGR A;  3D44 A;  3AWF A;  4OHI A;  1Q6N A;  5AWX A;  2I4H A;  3I7Z A;  4I8N A;  3ZM1 A;  1C86 A;  2VEW A;  3O3L A;  4WU3 A;  1L8G A;  2CNG A;  1L8K A;  5KA4 A;  1A5Y A;  3PS5 A;  3S3E A;  5KAC A;  4RHG A;  1NL9 A;  2CM7 A;  2QBR A;  4YAA A;  2QCJ A;  2J17 A;  1GFY A;  2QEP A;  2H4K A;  2H4V A;  2C7S A;  2PBN A;  3QCH A;  4ICZ A;  4RDD A;  2Y2F A;  1OES A;  1G7G A;  4H34 A;  4QBW A;  4R0S A;  3O4T A;  3EU0 A;  2OC3 A;  1U24 A;  2F46 A;  2QDC A;  3B7O A;  1VHR A;  3V0H A;  5KA0 A;  2QBP A;  1YTN A;  2B4O A;  2HC1 A;  1AAX A;  3O5X A;  1M3G A;  4KYR A;  3F9B A;  4QBE A;  2F6Z A;  2I6M A;  5BUG A;  1T48 A;  5MMZ B;  3MMJ A;  2ZN7 A;  3ZMP A;  2VEY A;  5KAD A;  3QCJ A;  4WU2 A;  2HCM A;  2P4D A;  1C83 A;  1PTV A;  1NWL A;  3BRH A;  4GS0 A;  5I6V A;  2SHP A;  1MKP A;  2H03 A;  5K22 A;  3N0A A;  1OEU A;  5KA9 A;  4GRZ A;  2A3K A;  1C88 A;  1NZ7 A;  2B07 A;  3O4S A;  2QBQ A;  2FJM A;  3D1O A;  3QCE A;  2I6J A;  5IBS A;  3SR9 A;  1G1F A;  5KA8 A;  3RZ2 A;  4GRY A;  2M3V A;  1YFO A;  2I6P A;  3D9C A;  4OHH A;  5GTJ A;  2F6F A;  3F9A A;  4NWF A;  2CJZ A;  2FJN A;  4JMJ A;  3GXH A;  5K25 A;  4TVV A;  1XRI A;  1G4U S;  2CMC A;  3S3F A;  1Q6J A;  3F41 A;  3QCB A;  4J51 A;  2ESB A;  1LQF A;  4DGX A;  2Q05 A;  3RO1 A;  2BGE A;  5K24 A;  2HY3 A;  2OOQ A;  5EHP A;  4QUM A;  2G6Z A;  1R6H A;  3OLR A;  1WRM A;  3RGQ A;  4DGP A;  2J16 A;  5LXQ B;  2P6X A;  1PXH A;  1I9S A;  2I75 A;  3QCK A;  4QAP A;  1QZ0 A;  4QAH A;  1J4X A;  2HXP A;  3EB1 A;  2GP0 A;  3MOW A;  1FPZ A;  1PA1 A;  3V0E A;  4Z6B A;  2CNI A;  3AWE A;  1OET A;  1ZCL A;  4RI5 A;  1YGU A;  1NNY A;  1ZZW A;  5KA7 A;  3A5K A;  3QCN A;  3F99 A;  2F6Y A;  2J16 B;  3EMU A;  4JMK A;  2H02 A;  1BZH A;  4IKC A;  1D5R A;  2G59 A;  4H1O A;  1PH0 A;  2B49 A;  2HB1 A;  2F6W A;  3BM8 A;  1LAR A;  4ZI4 A;  4B04 A;  1C87 A;  3I36 A;  1XXV A;  2H4G A;  3QKP A;  2PQ5 A;  2I6I A;  1ZCK A;  1NO6 A;  3ZM0 A;  2CM3 A;  5KA2 A;  5K9V A;  3CM3 A;  2QDM A;  1SUG A;  3A5J A;  4RH9 A;  1Q1M A;  2DXP A;  1G1H A;  4GE2 A;  4KYQ A;  2OUD A;  5K9W A;  4QUN A;  5KA3 A;  2CNH A;  1WCH A;  3QCI A;  2WGP A;  3S3K A;  4GE6 A;  2ZMM A;  3GXG A;  5KAA A;  1P15 A;  1OEO X;  2VEU A;  2NT2 A;  1JLN A;  3S3H A;  4NND A;  5BZX A;  3CWE A;  4GFU A;  4Y2E A;  1KAV A;  1PTY A;  5IBM A;  3MOZ A;  4OHE A;  2CNF A;  1OEV A;  4WOH A;  2JJD A;  4OHD A;  2QBS A;  5BX1 A;  3ZM2 A;  2Y96 A;  1WAX A;  4ZRT A;  2RF6 A;  2PSZ A;  2CMB A;  1FQ1 A;  2B3O A;  2NV5 A;  1C85 A;  1XXP A;  3ZM3 A;  2E0T A;  4AZ1 A;  1PTT A;  4NX8 A;  1XM2 A;  4KI9 A;  2HNQ A;  3S4E A;  1EEO A;  1Q6P A;  3AWG A;  4RKK A;  3BLU A;  3QCG A;  4BPC A;  1YZ4 A;  2QDP A;  5K23 A;  4OHL A;  2BIJ A;  5BZZ A;  2Q47 A;  3BLT A;  4PYH A;  1T4J A;  1ZC0 A;  3QCD A;  2NT7 A;  2I1Y A;  2I42 A;  2FH7 A;  4JNB A;  1YN9 A;  2A8B A;  4ZN5 A;  2OZ5 A;  1RXD A;  2HVL A;  2B4S A;  2MBC A;  2BV5 A;  1V3A A;  1EEN A;  3I80 A;  4HJQ A;  1G7F A;  2AZR A;  1YPT A;  1I57 A;  2AHS A;  1YWF A;  4GFV A;  3QCC A;  2F6T A;  2NLK A;  1BZC A;  1PTU A;  2CM2 A;  2CFV A;  5HDE A;  3D1H A;  2PA5 A;  2R0B A;  4D3P A;  2I4G A;  1XBO A;  3V0D A;  2VEX A;  4BJO A;  2C46 A;  1PA9 A;  2F71 A;  3ZV2 A;  3V0J A;  3SME A;  4GE5 A;  2PI7 A;  5EHR A;  2HC2 A;  3QCM A;  4ERC A;  4YR8 B;  2B4U A;  1NWE A;  1OEM X;  2CNE A;  4NYH A;  2I6O A;  4D3Q A;  1OHE A;  2I3R A;  3D1Q A;  1I9T A;  2NZ6 A;  2GJT A;  5KAB A;  2HNP A;  3V0I A;  1G1G A;  1GWZ A;  1T49 A;  1ONY A;  3ZMQ A;  1FPR A;  2F6V A;  2YDU A;  2I4E A;  3V0F A;  4D3R A;  2PT0 A;  5J8R A;  3EZZ A;  3O4U A;  1KAK A;  4RH5 A;  3V0G A;  3M4U A;  4NWG A;  1OHD A;  3F81 A;  4R0T A;  4HJP A;  1Q6S A;  4GWF A;  1QXK A;  2I5X A;  2BZL A;  5KA1 A;  2NTA A;  1Q6T A;  4MBB A;  1YTW A;  4Y14 A;  2I3U A;  3S4O A;  2QCT A;  1C84 A;  1PYN A;  4HRF A;  4R30 A;  3QCL A;  3LJ8 A;  1U25 A;  3D42 A;  3NME A;  2CMA A;  2VEV A;  5M43 A;  4PVG A;  1BZJ A;  3U96 A;  4RI4 A;  2CM8 A;  3QCF A;  1OHC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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