2P6XA

Crystal structure of human tyrosine phosphatase ptpn22
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
303
structure length
302
Chain Sequence
MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRYKDILPYDYSRVELSLITDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNSETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDKHSA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Large-scale structural analysis of the classical human protein tyrosine phosphatome.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 22
total genus 108
structure length 302
sequence length 303
chains with identical sequence B
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2007-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2p6xA00
3AWFA 2OOQA 1OEVA 3F9AA 5KACA 4Y14A 2NT2A 3ZM2A 1XXPA 1YWFA 3AWEA 3M4UA 3SMEA 1BZCA 2B4SA 3QCKA 2P6XA 4WU3A 2VEYA 4YAAA 4H34A 1KAVA 3V0JA 5AWXA 2I6JA 2HNQA 3A5KA 1LYVA 4QAPA 3ZM0A 2E0TA 4AZ1A 1PA1A 2F6YA 3ZV2A 1OEOX 4IKCA 2C7SA 4NX8A 1FQ1A 2VEXA 4PYHA 3S3EA 3F9BA 1R6HA 3D9CA 2F6ZA 2PBNA 3O4UA 1PH0A 3EMUA 1LARA 3F41A 5KA7A 2QBPA 2F71A 5BX1A 2QBRA 4KI9A 1PXHA 3QCBA 2Y2FA 3EB1A 1PTVA 2H03A 1VHRA 2B3OA 2I4HA 2F6WA 2MBCA 2PQ5A 3AWGA 4JMJA 4WTYA 3S3FA 4ERCA 5MMZB 2BV5A 3QKPA 3BM8A 1ECVA 1G1FA 5M43A 3S4EA 4GFUA 2IMGA 2ZN7A 3S3KA 2I6PA 2PSZA 4OHHA 4S0GA 1Q6JA 1PTTA 1EENA 2G6ZA 4GE5A 3QCFA 2B49A 2CM3A 1ONZA 4JBCA 3D1OA 4DGXA 3ZM3A 5K9VA 3CWEA 4HRFA 2VEWA 2OZ5A 1XBOA 1XXVA 2CNHA 3CM3A 4HJPA 5K25A 2YDUA 1MKPA 2Q47A 4J51A 2QEPA 3I80A 3I36A 4HJQA 1OEMX 2Y96A 1G1GA 2M3VA 4RH5A 2F6FA 2I42A 2I75A 1T48A 2I6IA 3OLRA 4RH9A 1NL9A 3OMHA 2CNGA 1I9TA 4GFVA 1FPRA 1LQFA 1L8GA 1U26A 3V0HA 5KABA 3O3LA 1OETA 2C46A 2CNFA 5K23A 2FJMA 2HXPA 1BZHA 2I6OA 2F6VA 1JF7A 1A5YA 1YGRA 4ZN5A 1JLNA 2CMAA 1C85A 5KA4A 4QUNA 5BZZA 1C88A 1Q6MA 4DGPA 3QCLA 4GE2A 4KYRA 1WRMA 1M3GA 3LJ8A 2NTAA 3PS5A 3RO1A 1X24A 4OHDA 2ZMMA 3F81A 2I6MA 3NMEA 2RF6A 1QZ0A 5KA0A 1RXDA 2HC1A 2PI7A 1OHCA 4OHLA 2H4KA 2VEVA 4B04A 4PVGA 2QBQA 4BJOA 2GP0A 5KA2A 5IBSA 1Q6NA 4GRZA 3RGOA 3MOZA 2QCJA 2I4EA 4NWFA 2H04A 1C86A 3ZMQA 1C83A 1C87A 2NZ6A 2CJZA 2FH7A 3GXHA 3RGQA 2G59A 2F6TA 3V0IA 4QAHA 2QDMA 5LXQB 1WCHA 2I3RA 4QUMA 5KA9A 2B4OA 3O4TA 1ONYA 1PA9A 3S4OA 3ZMPA 2F70A 2ESBA 1Q6SA 2HB1A 3QCMA 2OC3A 1G4WR 4TVVA 1BZJA 1YTWA 1J4XA 4QBWA 1P15A 1OHDA 3QKQA 1L8KA 4RDDA 4GRYA 2SHPA 5KA8A 1C84A 4QBEA 2A8BA 4I8NA 5K24A 1Q1MA 3QCHA 4RHGA 2DXPA 5KA3A 3D1QA 4JNBA 4R0TA 2WGPA 3B7OA 2CM8A 2PT0A 4RI5A 1U25A 2PA5A 1U24A 3O5XA 2CMBA 4H1OA 4NYHA 2AZRA 4OHIA 2J17A 1GWZA 1I9SA 1D5RA 4GWFA 4JMKA 4MBBA 4R30A 1T4JA 1RPMA 3QCEA 2JJDA 2BZLA 4RKKA 2J16A 1QXKA 1NWEA 3V0DA 4Y2EA 5I6VA 3D42A 1YTNA 1G4US 2GJTA 5BZXA 2B4PA 2GWOA 1YTSA 2I3UA 1NWLA 3QCNA 3V0EA 4WU2A 2CNIA 4ICZA 1NNYA 3QCJA 2BGEA 3V0FA 2HNPA 3RZ2A 2H4VA 2P4DA 3QCIA 2QDCA 4ZI4A 4D3QA 1ZCLA 3EZZA 4BPCA 4R0SA 2B4UA 1YN9A 5EHPA 5IBMA 5KAAA 5K9WA 3U96A 2BIJA 2H4GA 3N0AA 1G1HA 2F46A 3BRHA 1Q6TA 1NO6A 1T49A 5J8RA 1GFYA 2OUDA 4YR8B 5KADA 3A5JA 1ZCKA 1G7GA 3ZM1A 2BGDA 2A3KA 2CM2A 1V3AA 2CNEA 2CMCA 1ZZWA 3I7ZA 1YGUA 4ZRTA 3BLTA 2VEUA 1NZ7A 2CFVA 2NLKA 2I1YA 2Q05A 3S3HA 2AHSA 5GTJA 5BUGA 2I4GA 2J16B 1Q6PA 1XM2A 2HVLA 1EEOA 1KAKA 3MMJA 2QCTA 3EAXA 4NWGA 3H2XA 1PTYA 2HC2A 3D44A 4RI4A 3GXGA 2HY3A 4D3PA 4NNDA 2NV5A 3QCGA 1OESA 3BLUA 3SR9A 1AAXA 3QCDA 1YPTA 3MOWA 1I57A 3O4SA 3D1HA 1ZC0A 1OEUA 4GE6A 4KYQA 5KA1A 4D3RA 5EHRA 2QBSA 4Z6BA 3F99A 4WOHA 1XRIA 2FJNA 2I5XA 2QDPA 4GS0A 2CM7A 1WAXA 2R0BA 1G7FA 3QCCA 1PYNA 2NT7A 5K22A 1OHEA 3V0GA 1FPZA 1SUGA 3EU0A 5HDEA 2H02A 1PTUA 1YZ4A 2HCMA 1YFOA 2B07A 4OHEA
chains in the Genus database with same CATH superfamily
3AWFA 2OOQA 1OEVA 3F9AA 5KACA 2VTDA 2XJAA 4Y14A 2UAGA 1FGSA 2NT2A 3ZM2A 1XXPA 1YWFA 3AWEA 3M4UA 3SMEA 1BZCA 2B4SA 3QCKA 2P6XA 1EEHA 4WU3A 1P31A 2VEYA 4YAAA 4H34A 1KAVA 3V0JA 5AWXA 2I6JA 2HNQA 3A5KA 1LYVA 4QAPA 3ZM0A 2E0TA 2GCBA 4AZ1A 1PA1A 2F6YA 3ZV2A 1OEOX 4IKCA 2C7SA 4NX8A 4C13A 1FQ1A 2VEXA 4PYHA 3S3EA 3F9BA 1R6HA 3D9CA 2F6ZA 2PBNA 2JFGA 3O4UA 1PH0A 3EMUA 1LARA 3F41A 5KA7A 2GCAA 2QBPA 2F71A 5BX1A 2QBRA 4KI9A 1PXHA 3QCBA 2Y2FA 3EB1A 1PTVA 1JBVA 2H03A 1VHRA 2B3OA 2I4HA 2Y66A 2F6WA 2MBCA 2PQ5A 3AWGA 4JMJA 4WTYA 3S3FA 4ERCA 5MMZB 2BV5A 3QKPA 3BM8A 3PYZA 1ECVA 1G1FA 5M43A 3S4EA 4GFUA 2IMGA 2ZN7A 3S3KA 2I6PA 2PSZA 2WJPA 4OHHA 4S0GA 1Q6JA 1PTTA 1EENA 2G6ZA 4GE5A 1W7KA 3QCFA 2Y1OA 2B49A 2CM3A 1ONZA 4JBCA 3D1OA 4DGXA 1GQYA 3ZM3A 5K9VA 3CWEA 4HRFA 2VEWA 2OZ5A 1XBOA 1XXVA 2CNHA 3CM3A 4HJPA 5K25A 2YDUA 1MKPA 2Q47A 4J51A 2QEPA 3I80A 3I36A 4HJQA 1OEMX 3ZL8A 2Y96A 1G1GA 2XPCA 2M3VA 4RH5A 2F6FA 2I42A 2I75A 1T48A 2I6IA 3OLRA 3N2AA 4RH9A 1NL9A 3OMHA 2CNGA 1I9TA 4GFVA 1FPRA 1LQFA 1L8GA 1U26A 3V0HA 5KABA 3O3LA 1OETA 2C46A 2CNFA 5K23A 2FJMA 2HXPA 1BZHA 2I6OA 2F6VA 5A5EA 1JF7A 1A5YA 1YGRA 4ZN5A 1JLNA 2CMAA 1C85A 4UAGA 5KA4A 4QUNA 5BZZA 1C88A 2AM2A 1Q6MA 4QF5A 4DGPA 1J6UA 3QCLA 4GE2A 4KYRA 1WRMA 1M3GA 3LJ8A 2NTAA 3PS5A 2X5OA 3RO1A 1X24A 4OHDA 2ZMMA 3F81A 2I6MA 1E8CA 3NMEA 2GC6A 2RF6A 1QZ0A 5A5FA 5KA0A 1RXDA 2HC1A 2PI7A 1OHCA 4OHLA 2H4KA 2VEVA 4B04A 4PVGA 2QBQA 4BJOA 2GP0A 5KA2A 5IBSA 1Q6NA 4GRZA 3RGOA 3MOZA 2QCJA 2I4EA 4NWFA 2H04A 1C86A 3ZMQA 1C83A 1C87A 4BUBA 2NZ6A 2CJZA 2UUPA 2FH7A 3GXHA 3RGQA 1O5ZA 2G59A 2F6TA 3V0IA 4QAHA 2QDMA 5LXQB 1WCHA 2I3RA 4QUMA 5KA9A 3ZM6A 2B4OA 2VORA 3O4TA 1ONYA 1PA9A 3S4OA 2JFFA 3ZMPA 2Y67A 2F70A 2ESBA 1Q6SA 2HB1A 3QCMA 2OC3A 1G4WR 4CVMA 4TVVA 1BZJA 1YTWA 1J4XA 2VOSA 4QBWA 1P15A 1OHDA 3QKQA 1L8KA 4RDDA 4GRYA 2SHPA 5KA8A 1C84A 4QBEA 2A8BA 4I8NA 5K24A 1Q1MA 3QCHA 4RHGA 2DXPA 5KA3A 3D1QA 4JNBA 4R0TA 2WGPA 4CVKA 3B7OA 2CM8A 2PT0A 4RI5A 1U25A 2PA5A 1U24A 3O5XA 4C12A 2CMBA 4H1OA 4NYHA 2AZRA 4OHIA 2J17A 1GWZA 1I9SA 1D5RA 2VTEA 4GWFA 4JMKA 4MBBA 4R30A 1T4JA 1RPMA 3QCEA 2JJDA 2BZLA 4RKKA 2AM1A 2J16A 1QXKA 1NWEA 3V0DA 4Y2EA 5I6VA 3D42A 1YTNA 1G4US 2GJTA 5BZXA 3ZM5A 2B4PA 4ZIYA 1GQQA 2GWOA 1YTSA 2I3UA 1NWLA 3QCNA 3V0EA 4WU2A 2CNIA 4ICZA 1NNYA 3QCJA 2BGEA 3V0FA 2HNPA 3RZ2A 2JFHA 2H4VA 2P4DA 3QCIA 2F00A 2QDCA 4CVLA 4ZI4A 2UUOA 4D3QA 1ZCLA 1UAGA 3EZZA 4BPCA 4R0SA 2B4UA 1YN9A 5EHPA 5IBMA 5KAAA 5K9WA 3HN7A 3U96A 2BIJA 2H4GA 3N0AA 3LK7A 1G1HA 2F46A 3BRHA 1Q6TA 1NO6A 1T49A 5J8RA 3UAGA 1GFYA 2OUDA 4YR8B 5KADA 3A5JA 1E0DA 1ZCKA 1G7GA 3QCZA 3ZM1A 2BGDA 2A3KA 2CM2A 1V3AA 2CNEA 2CMCA 1ZZWA 3I7ZA 1YGUA 4ZRTA 3BLTA 2VEUA 1NZ7A 2CFVA 2NLKA 2I1YA 2Q05A 3S3HA 4QDIA 1GG4A 2AHSA 5GTJA 5BUGA 2I4GA 2J16B 1Q6PA 1XM2A 1W78A 2HVLA 2Y68A 1EEOA 1KAKA 3MMJA 2QCTA 3EAXA 4NWGA 3H2XA 1PTYA 2HC2A 3D44A 4RI4A 3GXGA 2HY3A 4D3PA 4NNDA 2NV5A 3QCGA 1OESA 3BLUA 3SR9A 1AAXA 3QCDA 1YPTA 3MOWA 1I57A 3O4SA 3D1HA 1ZC0A 1OEUA 4GE6A 2WTZA 4KYQA 5KA1A 4D3RA 5EHRA 2QBSA 4Z6BA 3F99A 3NRSA 4WOHA 1XRIA 4BUCA 4HV4A 2FJNA 2GC5A 2I5XA 2QDPA 4GS0A 2CM7A 1WAXA 2R0BA 1G7FA 3QCCA 1PYNA 2NT7A 3MVNA 1JBWA 1OHEA 5K22A 3V0GA 1FPZA 1SUGA 1P3DA 3EU0A 5HDEA 2H02A 1PTUA 1YZ4A 2HCMA 1YFOA 2B07A 4OHEA
chains in the Genus database with same CATH topology
3AWFA 2OOQA 1OEVA 3F9AA 5KACA 4Y14A 2NT2A 3ZM2A 1XXPA 1YWFA 3AWEA 3M4UA 3SMEA 1BZCA 2B4SA 3QCKA 2P6XA 4WU3A 2VEYA 4YAAA 4H34A 1KAVA 3V0JA 5AWXA 2I6JA 2HNQA 3A5KA 1LYVA 4QAPA 3ZM0A 2E0TA 4AZ1A 1PA1A 2F6YA 3ZV2A 1OEOX 4IKCA 2C7SA 4NX8A 1FQ1A 2VEXA 4PYHA 3S3EA 3F9BA 1R6HA 3D9CA 2F6ZA 2PBNA 3O4UA 1PH0A 3EMUA 1LARA 3F41A 5KA7A 2QBPA 2F71A 5BX1A 2QBRA 4KI9A 1PXHA 3QCBA 2Y2FA 3EB1A 1PTVA 2H03A 1VHRA 2B3OA 2I4HA 2F6WA 2MBCA 2PQ5A 3AWGA 4JMJA 4WTYA 3S3FA 4ERCA 5MMZB 2BV5A 3QKPA 3BM8A 1ECVA 1G1FA 5M43A 3S4EA 4GFUA 2IMGA 2ZN7A 3S3KA 2I6PA 2PSZA 4OHHA 4S0GA 1Q6JA 1PTTA 1EENA 2G6ZA 4GE5A 3QCFA 2B49A 2CM3A 1ONZA 4JBCA 3D1OA 4DGXA 3ZM3A 5K9VA 3CWEA 4HRFA 2VEWA 2OZ5A 1XBOA 1XXVA 2CNHA 3CM3A 4HJPA 5K25A 2YDUA 1MKPA 2Q47A 4J51A 2QEPA 3I80A 3I36A 4HJQA 1OEMX 2Y96A 1G1GA 2M3VA 4RH5A 2F6FA 2I42A 2I75A 1T48A 2I6IA 3OLRA 4RH9A 1NL9A 3OMHA 2CNGA 1I9TA 4GFVA 1FPRA 1LQFA 1L8GA 1U26A 3V0HA 5KABA 3O3LA 1OETA 2C46A 2CNFA 5K23A 2FJMA 2HXPA 1BZHA 2I6OA 2F6VA 1JF7A 1A5YA 1YGRA 4ZN5A 1JLNA 2CMAA 1C85A 5KA4A 4QUNA 5BZZA 1C88A 1Q6MA 4DGPA 3QCLA 4GE2A 4KYRA 1WRMA 1M3GA 3LJ8A 2NTAA 3PS5A 3RO1A 1X24A 4OHDA 2ZMMA 3F81A 2I6MA 3NMEA 2RF6A 1QZ0A 5KA0A 1RXDA 2HC1A 2PI7A 1OHCA 4OHLA 2H4KA 2VEVA 4B04A 4PVGA 2QBQA 4BJOA 2GP0A 5KA2A 5IBSA 1Q6NA 4GRZA 3RGOA 3MOZA 2QCJA 2I4EA 4NWFA 2H04A 1C86A 3ZMQA 1C83A 1C87A 2NZ6A 2CJZA 2FH7A 3GXHA 3RGQA 2G59A 2F6TA 3V0IA 4QAHA 2QDMA 5LXQB 1WCHA 2I3RA 4QUMA 5KA9A 2B4OA 3O4TA 1ONYA 1PA9A 3S4OA 3ZMPA 2F70A 2ESBA 1Q6SA 2HB1A 3QCMA 2OC3A 1G4WR 4TVVA 1BZJA 1YTWA 1J4XA 4QBWA 1P15A 1OHDA 3QKQA 1L8KA 4RDDA 4GRYA 2SHPA 5KA8A 1C84A 4QBEA 2A8BA 4I8NA 5K24A 1Q1MA 3QCHA 4RHGA 2DXPA 5KA3A 3D1QA 4JNBA 4R0TA 2WGPA 3B7OA 2CM8A 2PT0A 4RI5A 1U25A 2PA5A 1U24A 3O5XA 2CMBA 4H1OA 4NYHA 2AZRA 4OHIA 2J17A 1GWZA 1I9SA 1D5RA 4GWFA 4JMKA 4MBBA 4R30A 1T4JA 1RPMA 3QCEA 2JJDA 2BZLA 4RKKA 2J16A 1QXKA 1NWEA 3V0DA 4Y2EA 5I6VA 3D42A 1YTNA 1G4US 2GJTA 5BZXA 2B4PA 2GWOA 1YTSA 2I3UA 1NWLA 3QCNA 3V0EA 4WU2A 2CNIA 4ICZA 1NNYA 3QCJA 2BGEA 3V0FA 2HNPA 3RZ2A 2H4VA 2P4DA 3QCIA 2QDCA 4ZI4A 4D3QA 1ZCLA 3EZZA 4BPCA 4R0SA 2B4UA 1YN9A 5EHPA 5IBMA 5KAAA 5K9WA 3U96A 2BIJA 2H4GA 3N0AA 1G1HA 2F46A 3BRHA 1Q6TA 1NO6A 1T49A 5J8RA 1GFYA 2OUDA 4YR8B 5KADA 3A5JA 1ZCKA 1G7GA 3ZM1A 2BGDA 2A3KA 2CM2A 1V3AA 2CNEA 2CMCA 1ZZWA 3I7ZA 1YGUA 4ZRTA 3BLTA 2VEUA 1NZ7A 2CFVA 2NLKA 2I1YA 2Q05A 3S3HA 2AHSA 5GTJA 5BUGA 2I4GA 2J16B 1Q6PA 1XM2A 2HVLA 1EEOA 1KAKA 3MMJA 2QCTA 3EAXA 4NWGA 3H2XA 1PTYA 2HC2A 3D44A 4RI4A 3GXGA 2HY3A 4D3PA 4NNDA 2NV5A 3QCGA 1OESA 3BLUA 3SR9A 1AAXA 3QCDA 1YPTA 3MOWA 1I57A 3O4SA 3D1HA 1ZC0A 1OEUA 4GE6A 4KYQA 5KA1A 4D3RA 5EHRA 2QBSA 4Z6BA 3F99A 4WOHA 1XRIA 2FJNA 2I5XA 2QDPA 4GS0A 2CM7A 1WAXA 2R0BA 1G7FA 3QCCA 1PYNA 2NT7A 5K22A 1OHEA 3V0GA 1FPZA 1SUGA 3EU0A 5HDEA 2H02A 1PTUA 1YZ4A 2HCMA 1YFOA 2B07A 4OHEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AWF A;  2OOQ A;  1OEV A;  3F9A A;  5KAC A;  4Y14 A;  2NT2 A;  3ZM2 A;  1XXP A;  1YWF A;  3AWE A;  3M4U A;  3SME A;  1BZC A;  2B4S A;  3QCK A;  2P6X A;  4WU3 A;  2VEY A;  4YAA A;  4H34 A;  1KAV A;  3V0J A;  5AWX A;  2I6J A;  2HNQ A;  3A5K A;  1LYV A;  4QAP A;  3ZM0 A;  2E0T A;  4AZ1 A;  1PA1 A;  2F6Y A;  3ZV2 A;  1OEO X;  4IKC A;  2C7S A;  4NX8 A;  1FQ1 A;  2VEX A;  4PYH A;  3S3E A;  3F9B A;  1R6H A;  3D9C A;  2F6Z A;  2PBN A;  3O4U A;  1PH0 A;  3EMU A;  1LAR A;  3F41 A;  5KA7 A;  2QBP A;  2F71 A;  5BX1 A;  2QBR A;  4KI9 A;  1PXH A;  3QCB A;  2Y2F A;  3EB1 A;  1PTV A;  2H03 A;  1VHR A;  2B3O A;  2I4H A;  2F6W A;  2MBC A;  2PQ5 A;  3AWG A;  4JMJ A;  4WTY A;  3S3F A;  4ERC A;  5MMZ B;  2BV5 A;  3QKP A;  3BM8 A;  1ECV A;  1G1F A;  5M43 A;  3S4E A;  4GFU A;  2IMG A;  2ZN7 A;  3S3K A;  2I6P A;  2PSZ A;  4OHH A;  4S0G A;  1Q6J A;  1PTT A;  1EEN A;  2G6Z A;  4GE5 A;  3QCF A;  2B49 A;  2CM3 A;  1ONZ A;  4JBC A;  3D1O A;  4DGX A;  3ZM3 A;  5K9V A;  3CWE A;  4HRF A;  2VEW A;  2OZ5 A;  1XBO A;  1XXV A;  2CNH A;  3CM3 A;  4HJP A;  5K25 A;  2YDU A;  1MKP A;  2Q47 A;  4J51 A;  2QEP A;  3I80 A;  3I36 A;  4HJQ A;  1OEM X;  2Y96 A;  1G1G A;  2M3V A;  4RH5 A;  2F6F A;  2I42 A;  2I75 A;  1T48 A;  2I6I A;  3OLR A;  4RH9 A;  1NL9 A;  3OMH A;  2CNG A;  1I9T A;  4GFV A;  1FPR A;  1LQF A;  1L8G A;  1U26 A;  3V0H A;  5KAB A;  3O3L A;  1OET A;  2C46 A;  2CNF A;  5K23 A;  2FJM A;  2HXP A;  1BZH A;  2I6O A;  2F6V A;  1JF7 A;  1A5Y A;  1YGR A;  4ZN5 A;  1JLN A;  2CMA A;  1C85 A;  5KA4 A;  4QUN A;  5BZZ A;  1C88 A;  1Q6M A;  4DGP A;  3QCL A;  4GE2 A;  4KYR A;  1WRM A;  1M3G A;  3LJ8 A;  2NTA A;  3PS5 A;  3RO1 A;  1X24 A;  4OHD A;  2ZMM A;  3F81 A;  2I6M A;  3NME A;  2RF6 A;  1QZ0 A;  5KA0 A;  1RXD A;  2HC1 A;  2PI7 A;  1OHC A;  4OHL A;  2H4K A;  2VEV A;  4B04 A;  4PVG A;  2QBQ A;  4BJO A;  2GP0 A;  5KA2 A;  5IBS A;  1Q6N A;  4GRZ A;  3RGO A;  3MOZ A;  2QCJ A;  2I4E A;  4NWF A;  2H04 A;  1C86 A;  3ZMQ A;  1C83 A;  1C87 A;  2NZ6 A;  2CJZ A;  2FH7 A;  3GXH A;  3RGQ A;  2G59 A;  2F6T A;  3V0I A;  4QAH A;  2QDM A;  5LXQ B;  1WCH A;  2I3R A;  4QUM A;  5KA9 A;  2B4O A;  3O4T A;  1ONY A;  1PA9 A;  3S4O A;  3ZMP A;  2F70 A;  2ESB A;  1Q6S A;  2HB1 A;  3QCM A;  2OC3 A;  1G4W R;  4TVV A;  1BZJ A;  1YTW A;  1J4X A;  4QBW A;  1P15 A;  1OHD A;  3QKQ A;  1L8K A;  4RDD A;  4GRY A;  2SHP A;  5KA8 A;  1C84 A;  4QBE A;  2A8B A;  4I8N A;  5K24 A;  1Q1M A;  3QCH A;  4RHG A;  2DXP A;  5KA3 A;  3D1Q A;  4JNB A;  4R0T A;  2WGP A;  3B7O A;  2CM8 A;  2PT0 A;  4RI5 A;  1U25 A;  2PA5 A;  1U24 A;  3O5X A;  2CMB A;  4H1O A;  4NYH A;  2AZR A;  4OHI A;  2J17 A;  1GWZ A;  1I9S A;  1D5R A;  4GWF A;  4JMK A;  4MBB A;  4R30 A;  1T4J A;  1RPM A;  3QCE A;  2JJD A;  2BZL A;  4RKK A;  2J16 A;  1QXK A;  1NWE A;  3V0D A;  4Y2E A;  5I6V A;  3D42 A;  1YTN A;  1G4U S;  2GJT A;  5BZX A;  2B4P A;  2GWO A;  1YTS A;  2I3U A;  1NWL A;  3QCN A;  3V0E A;  4WU2 A;  2CNI A;  4ICZ A;  1NNY A;  3QCJ A;  2BGE A;  3V0F A;  2HNP A;  3RZ2 A;  2H4V A;  2P4D A;  3QCI A;  2QDC A;  4ZI4 A;  4D3Q A;  1ZCL A;  3EZZ A;  4BPC A;  4R0S A;  2B4U A;  1YN9 A;  5EHP A;  5IBM A;  5KAA A;  5K9W A;  3U96 A;  2BIJ A;  2H4G A;  3N0A A;  1G1H A;  2F46 A;  3BRH A;  1Q6T A;  1NO6 A;  1T49 A;  5J8R A;  1GFY A;  2OUD A;  4YR8 B;  5KAD A;  3A5J A;  1ZCK A;  1G7G A;  3ZM1 A;  2BGD A;  2A3K A;  2CM2 A;  1V3A A;  2CNE A;  2CMC A;  1ZZW A;  3I7Z A;  1YGU A;  4ZRT A;  3BLT A;  2VEU A;  1NZ7 A;  2CFV A;  2NLK A;  2I1Y A;  2Q05 A;  3S3H A;  2AHS A;  5GTJ A;  5BUG A;  2I4G A;  2J16 B;  1Q6P A;  1XM2 A;  2HVL A;  1EEO A;  1KAK A;  3MMJ A;  2QCT A;  3EAX A;  4NWG A;  3H2X A;  1PTY A;  2HC2 A;  3D44 A;  4RI4 A;  3GXG A;  2HY3 A;  4D3P A;  4NND A;  2NV5 A;  3QCG A;  1OES A;  3BLU A;  3SR9 A;  1AAX A;  3QCD A;  1YPT A;  3MOW A;  1I57 A;  3O4S A;  3D1H A;  1ZC0 A;  1OEU A;  4GE6 A;  4KYQ A;  5KA1 A;  4D3R A;  5EHR A;  2QBS A;  4Z6B A;  3F99 A;  4WOH A;  1XRI A;  2FJN A;  2I5X A;  2QDP A;  4GS0 A;  2CM7 A;  1WAX A;  2R0B A;  1G7F A;  3QCC A;  1PYN A;  2NT7 A;  5K22 A;  1OHE A;  3V0G A;  1FPZ A;  1SUG A;  3EU0 A;  5HDE A;  2H02 A;  1PTU A;  1YZ4 A;  2HCM A;  1YFO A;  2B07 A;  4OHE A; 
#chains in the Genus database with same CATH topology
 3AWF A;  2OOQ A;  1OEV A;  3F9A A;  5KAC A;  2VTD A;  2XJA A;  4Y14 A;  2UAG A;  1FGS A;  2NT2 A;  3ZM2 A;  1XXP A;  1YWF A;  3AWE A;  3M4U A;  3SME A;  1BZC A;  2B4S A;  3QCK A;  2P6X A;  1EEH A;  4WU3 A;  1P31 A;  2VEY A;  4YAA A;  4H34 A;  1KAV A;  3V0J A;  5AWX A;  2I6J A;  2HNQ A;  3A5K A;  1LYV A;  4QAP A;  3ZM0 A;  2E0T A;  2GCB A;  4AZ1 A;  1PA1 A;  2F6Y A;  3ZV2 A;  1OEO X;  4IKC A;  2C7S A;  4NX8 A;  4C13 A;  1FQ1 A;  2VEX A;  4PYH A;  3S3E A;  3F9B A;  1R6H A;  3D9C A;  2F6Z A;  2PBN A;  2JFG A;  3O4U A;  1PH0 A;  3EMU A;  1LAR A;  3F41 A;  5KA7 A;  2GCA A;  2QBP A;  2F71 A;  5BX1 A;  2QBR A;  4KI9 A;  1PXH A;  3QCB A;  2Y2F A;  3EB1 A;  1PTV A;  1JBV A;  2H03 A;  1VHR A;  2B3O A;  2I4H A;  2Y66 A;  2F6W A;  2MBC A;  2PQ5 A;  3AWG A;  4JMJ A;  4WTY A;  3S3F A;  4ERC A;  5MMZ B;  2BV5 A;  3QKP A;  3BM8 A;  3PYZ A;  1ECV A;  1G1F A;  5M43 A;  3S4E A;  4GFU A;  2IMG A;  2ZN7 A;  3S3K A;  2I6P A;  2PSZ A;  2WJP A;  4OHH A;  4S0G A;  1Q6J A;  1PTT A;  1EEN A;  2G6Z A;  4GE5 A;  1W7K A;  3QCF A;  2Y1O A;  2B49 A;  2CM3 A;  1ONZ A;  4JBC A;  3D1O A;  4DGX A;  1GQY A;  3ZM3 A;  5K9V A;  3CWE A;  4HRF A;  2VEW A;  2OZ5 A;  1XBO A;  1XXV A;  2CNH A;  3CM3 A;  4HJP A;  5K25 A;  2YDU A;  1MKP A;  2Q47 A;  4J51 A;  2QEP A;  3I80 A;  3I36 A;  4HJQ A;  1OEM X;  3ZL8 A;  2Y96 A;  1G1G A;  2XPC A;  2M3V A;  4RH5 A;  2F6F A;  2I42 A;  2I75 A;  1T48 A;  2I6I A;  3OLR A;  3N2A A;  4RH9 A;  1NL9 A;  3OMH A;  2CNG A;  1I9T A;  4GFV A;  1FPR A;  1LQF A;  1L8G A;  1U26 A;  3V0H A;  5KAB A;  3O3L A;  1OET A;  2C46 A;  2CNF A;  5K23 A;  2FJM A;  2HXP A;  1BZH A;  2I6O A;  2F6V A;  5A5E A;  1JF7 A;  1A5Y A;  1YGR A;  4ZN5 A;  1JLN A;  2CMA A;  1C85 A;  4UAG A;  5KA4 A;  4QUN A;  5BZZ A;  1C88 A;  2AM2 A;  1Q6M A;  4QF5 A;  4DGP A;  1J6U A;  3QCL A;  4GE2 A;  4KYR A;  1WRM A;  1M3G A;  3LJ8 A;  2NTA A;  3PS5 A;  2X5O A;  3RO1 A;  1X24 A;  4OHD A;  2ZMM A;  3F81 A;  2I6M A;  1E8C A;  3NME A;  2GC6 A;  2RF6 A;  1QZ0 A;  5A5F A;  5KA0 A;  1RXD A;  2HC1 A;  2PI7 A;  1OHC A;  4OHL A;  2H4K A;  2VEV A;  4B04 A;  4PVG A;  2QBQ A;  4BJO A;  2GP0 A;  5KA2 A;  5IBS A;  1Q6N A;  4GRZ A;  3RGO A;  3MOZ A;  2QCJ A;  2I4E A;  4NWF A;  2H04 A;  1C86 A;  3ZMQ A;  1C83 A;  1C87 A;  4BUB A;  2NZ6 A;  2CJZ A;  2UUP A;  2FH7 A;  3GXH A;  3RGQ A;  1O5Z A;  2G59 A;  2F6T A;  3V0I A;  4QAH A;  2QDM A;  5LXQ B;  1WCH A;  2I3R A;  4QUM A;  5KA9 A;  3ZM6 A;  2B4O A;  2VOR A;  3O4T A;  1ONY A;  1PA9 A;  3S4O A;  2JFF A;  3ZMP A;  2Y67 A;  2F70 A;  2ESB A;  1Q6S A;  2HB1 A;  3QCM A;  2OC3 A;  1G4W R;  4CVM A;  4TVV A;  1BZJ A;  1YTW A;  1J4X A;  2VOS A;  4QBW A;  1P15 A;  1OHD A;  3QKQ A;  1L8K A;  4RDD A;  4GRY A;  2SHP A;  5KA8 A;  1C84 A;  4QBE A;  2A8B A;  4I8N A;  5K24 A;  1Q1M A;  3QCH A;  4RHG A;  2DXP A;  5KA3 A;  3D1Q A;  4JNB A;  4R0T A;  2WGP A;  4CVK A;  3B7O A;  2CM8 A;  2PT0 A;  4RI5 A;  1U25 A;  2PA5 A;  1U24 A;  3O5X A;  4C12 A;  2CMB A;  4H1O A;  4NYH A;  2AZR A;  4OHI A;  2J17 A;  1GWZ A;  1I9S A;  1D5R A;  2VTE A;  4GWF A;  4JMK A;  4MBB A;  4R30 A;  1T4J A;  1RPM A;  3QCE A;  2JJD A;  2BZL A;  4RKK A;  2AM1 A;  2J16 A;  1QXK A;  1NWE A;  3V0D A;  4Y2E A;  5I6V A;  3D42 A;  1YTN A;  1G4U S;  2GJT A;  5BZX A;  3ZM5 A;  2B4P A;  4ZIY A;  1GQQ A;  2GWO A;  1YTS A;  2I3U A;  1NWL A;  3QCN A;  3V0E A;  4WU2 A;  2CNI A;  4ICZ A;  1NNY A;  3QCJ A;  2BGE A;  3V0F A;  2HNP A;  3RZ2 A;  2JFH A;  2H4V A;  2P4D A;  3QCI A;  2F00 A;  2QDC A;  4CVL A;  4ZI4 A;  2UUO A;  4D3Q A;  1ZCL A;  1UAG A;  3EZZ A;  4BPC A;  4R0S A;  2B4U A;  1YN9 A;  5EHP A;  5IBM A;  5KAA A;  5K9W A;  3HN7 A;  3U96 A;  2BIJ A;  2H4G A;  3N0A A;  3LK7 A;  1G1H A;  2F46 A;  3BRH A;  1Q6T A;  1NO6 A;  1T49 A;  5J8R A;  3UAG A;  1GFY A;  2OUD A;  4YR8 B;  5KAD A;  3A5J A;  1E0D A;  1ZCK A;  1G7G A;  3QCZ A;  3ZM1 A;  2BGD A;  2A3K A;  2CM2 A;  1V3A A;  2CNE A;  2CMC A;  1ZZW A;  3I7Z A;  1YGU A;  4ZRT A;  3BLT A;  2VEU A;  1NZ7 A;  2CFV A;  2NLK A;  2I1Y A;  2Q05 A;  3S3H A;  4QDI A;  1GG4 A;  2AHS A;  5GTJ A;  5BUG A;  2I4G A;  2J16 B;  1Q6P A;  1XM2 A;  1W78 A;  2HVL A;  2Y68 A;  1EEO A;  1KAK A;  3MMJ A;  2QCT A;  3EAX A;  4NWG A;  3H2X A;  1PTY A;  2HC2 A;  3D44 A;  4RI4 A;  3GXG A;  2HY3 A;  4D3P A;  4NND A;  2NV5 A;  3QCG A;  1OES A;  3BLU A;  3SR9 A;  1AAX A;  3QCD A;  1YPT A;  3MOW A;  1I57 A;  3O4S A;  3D1H A;  1ZC0 A;  1OEU A;  4GE6 A;  2WTZ A;  4KYQ A;  5KA1 A;  4D3R A;  5EHR A;  2QBS A;  4Z6B A;  3F99 A;  3NRS A;  4WOH A;  1XRI A;  4BUC A;  4HV4 A;  2FJN A;  2GC5 A;  2I5X A;  2QDP A;  4GS0 A;  2CM7 A;  1WAX A;  2R0B A;  1G7F A;  3QCC A;  1PYN A;  2NT7 A;  3MVN A;  1JBW A;  1OHE A;  5K22 A;  3V0G A;  1FPZ A;  1SUG A;  1P3D A;  3EU0 A;  5HDE A;  2H02 A;  1PTU A;  1YZ4 A;  2HCM A;  1YFO A;  2B07 A;  4OHE A; 
#chains in the Genus database with same CATH homology
 3AWF A;  2OOQ A;  1OEV A;  3F9A A;  5KAC A;  4Y14 A;  2NT2 A;  3ZM2 A;  1XXP A;  1YWF A;  3AWE A;  3M4U A;  3SME A;  1BZC A;  2B4S A;  3QCK A;  2P6X A;  4WU3 A;  2VEY A;  4YAA A;  4H34 A;  1KAV A;  3V0J A;  5AWX A;  2I6J A;  2HNQ A;  3A5K A;  1LYV A;  4QAP A;  3ZM0 A;  2E0T A;  4AZ1 A;  1PA1 A;  2F6Y A;  3ZV2 A;  1OEO X;  4IKC A;  2C7S A;  4NX8 A;  1FQ1 A;  2VEX A;  4PYH A;  3S3E A;  3F9B A;  1R6H A;  3D9C A;  2F6Z A;  2PBN A;  3O4U A;  1PH0 A;  3EMU A;  1LAR A;  3F41 A;  5KA7 A;  2QBP A;  2F71 A;  5BX1 A;  2QBR A;  4KI9 A;  1PXH A;  3QCB A;  2Y2F A;  3EB1 A;  1PTV A;  2H03 A;  1VHR A;  2B3O A;  2I4H A;  2F6W A;  2MBC A;  2PQ5 A;  3AWG A;  4JMJ A;  4WTY A;  3S3F A;  4ERC A;  5MMZ B;  2BV5 A;  3QKP A;  3BM8 A;  1ECV A;  1G1F A;  5M43 A;  3S4E A;  4GFU A;  2IMG A;  2ZN7 A;  3S3K A;  2I6P A;  2PSZ A;  4OHH A;  4S0G A;  1Q6J A;  1PTT A;  1EEN A;  2G6Z A;  4GE5 A;  3QCF A;  2B49 A;  2CM3 A;  1ONZ A;  4JBC A;  3D1O A;  4DGX A;  3ZM3 A;  5K9V A;  3CWE A;  4HRF A;  2VEW A;  2OZ5 A;  1XBO A;  1XXV A;  2CNH A;  3CM3 A;  4HJP A;  5K25 A;  2YDU A;  1MKP A;  2Q47 A;  4J51 A;  2QEP A;  3I80 A;  3I36 A;  4HJQ A;  1OEM X;  2Y96 A;  1G1G A;  2M3V A;  4RH5 A;  2F6F A;  2I42 A;  2I75 A;  1T48 A;  2I6I A;  3OLR A;  4RH9 A;  1NL9 A;  3OMH A;  2CNG A;  1I9T A;  4GFV A;  1FPR A;  1LQF A;  1L8G A;  1U26 A;  3V0H A;  5KAB A;  3O3L A;  1OET A;  2C46 A;  2CNF A;  5K23 A;  2FJM A;  2HXP A;  1BZH A;  2I6O A;  2F6V A;  1JF7 A;  1A5Y A;  1YGR A;  4ZN5 A;  1JLN A;  2CMA A;  1C85 A;  5KA4 A;  4QUN A;  5BZZ A;  1C88 A;  1Q6M A;  4DGP A;  3QCL A;  4GE2 A;  4KYR A;  1WRM A;  1M3G A;  3LJ8 A;  2NTA A;  3PS5 A;  3RO1 A;  1X24 A;  4OHD A;  2ZMM A;  3F81 A;  2I6M A;  3NME A;  2RF6 A;  1QZ0 A;  5KA0 A;  1RXD A;  2HC1 A;  2PI7 A;  1OHC A;  4OHL A;  2H4K A;  2VEV A;  4B04 A;  4PVG A;  2QBQ A;  4BJO A;  2GP0 A;  5KA2 A;  5IBS A;  1Q6N A;  4GRZ A;  3RGO A;  3MOZ A;  2QCJ A;  2I4E A;  4NWF A;  2H04 A;  1C86 A;  3ZMQ A;  1C83 A;  1C87 A;  2NZ6 A;  2CJZ A;  2FH7 A;  3GXH A;  3RGQ A;  2G59 A;  2F6T A;  3V0I A;  4QAH A;  2QDM A;  5LXQ B;  1WCH A;  2I3R A;  4QUM A;  5KA9 A;  2B4O A;  3O4T A;  1ONY A;  1PA9 A;  3S4O A;  3ZMP A;  2F70 A;  2ESB A;  1Q6S A;  2HB1 A;  3QCM A;  2OC3 A;  1G4W R;  4TVV A;  1BZJ A;  1YTW A;  1J4X A;  4QBW A;  1P15 A;  1OHD A;  3QKQ A;  1L8K A;  4RDD A;  4GRY A;  2SHP A;  5KA8 A;  1C84 A;  4QBE A;  2A8B A;  4I8N A;  5K24 A;  1Q1M A;  3QCH A;  4RHG A;  2DXP A;  5KA3 A;  3D1Q A;  4JNB A;  4R0T A;  2WGP A;  3B7O A;  2CM8 A;  2PT0 A;  4RI5 A;  1U25 A;  2PA5 A;  1U24 A;  3O5X A;  2CMB A;  4H1O A;  4NYH A;  2AZR A;  4OHI A;  2J17 A;  1GWZ A;  1I9S A;  1D5R A;  4GWF A;  4JMK A;  4MBB A;  4R30 A;  1T4J A;  1RPM A;  3QCE A;  2JJD A;  2BZL A;  4RKK A;  2J16 A;  1QXK A;  1NWE A;  3V0D A;  4Y2E A;  5I6V A;  3D42 A;  1YTN A;  1G4U S;  2GJT A;  5BZX A;  2B4P A;  2GWO A;  1YTS A;  2I3U A;  1NWL A;  3QCN A;  3V0E A;  4WU2 A;  2CNI A;  4ICZ A;  1NNY A;  3QCJ A;  2BGE A;  3V0F A;  2HNP A;  3RZ2 A;  2H4V A;  2P4D A;  3QCI A;  2QDC A;  4ZI4 A;  4D3Q A;  1ZCL A;  3EZZ A;  4BPC A;  4R0S A;  2B4U A;  1YN9 A;  5EHP A;  5IBM A;  5KAA A;  5K9W A;  3U96 A;  2BIJ A;  2H4G A;  3N0A A;  1G1H A;  2F46 A;  3BRH A;  1Q6T A;  1NO6 A;  1T49 A;  5J8R A;  1GFY A;  2OUD A;  4YR8 B;  5KAD A;  3A5J A;  1ZCK A;  1G7G A;  3ZM1 A;  2BGD A;  2A3K A;  2CM2 A;  1V3A A;  2CNE A;  2CMC A;  1ZZW A;  3I7Z A;  1YGU A;  4ZRT A;  3BLT A;  2VEU A;  1NZ7 A;  2CFV A;  2NLK A;  2I1Y A;  2Q05 A;  3S3H A;  2AHS A;  5GTJ A;  5BUG A;  2I4G A;  2J16 B;  1Q6P A;  1XM2 A;  2HVL A;  1EEO A;  1KAK A;  3MMJ A;  2QCT A;  3EAX A;  4NWG A;  3H2X A;  1PTY A;  2HC2 A;  3D44 A;  4RI4 A;  3GXG A;  2HY3 A;  4D3P A;  4NND A;  2NV5 A;  3QCG A;  1OES A;  3BLU A;  3SR9 A;  1AAX A;  3QCD A;  1YPT A;  3MOW A;  1I57 A;  3O4S A;  3D1H A;  1ZC0 A;  1OEU A;  4GE6 A;  4KYQ A;  5KA1 A;  4D3R A;  5EHR A;  2QBS A;  4Z6B A;  3F99 A;  4WOH A;  1XRI A;  2FJN A;  2I5X A;  2QDP A;  4GS0 A;  2CM7 A;  1WAX A;  2R0B A;  1G7F A;  3QCC A;  1PYN A;  2NT7 A;  5K22 A;  1OHE A;  3V0G A;  1FPZ A;  1SUG A;  3EU0 A;  5HDE A;  2H02 A;  1PTU A;  1YZ4 A;  2HCM A;  1YFO A;  2B07 A;  4OHE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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