2PHBB

An orally efficacious factor xa inhibitor
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
51
structure length
51
Chain Sequence
LCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The discovery of (2R,4R)-N-(4-chlorophenyl)-N- (2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl)-4-methoxypyrrolidine-1,2-dicarboxamide (PD 0348292), an orally efficacious factor Xa inhibitor
pubmed doi rcsb
source organism Homo sapiens
molecule tags Blood clotting
molecule keywords Coagulation factor X, heavy chain
total genus 10
structure length 51
sequence length 51
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2007-04-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2phbB00
3TBDA 2KV4A 2VWOL 2VVCK 5JBAE 2CJIB 2YGPA 5K0HB 1JL9A 3LTGD 5CKNA 3KK6A 3N8WA 1IOEL 4X8TL 4JYUL 3BT2A 2WPKE 2JKHL 4G1MB 3HS6A 4Y7BB 1ATBA 1X7AL 3GCXE 3LTFB 3KCGL 2K2TA 3HO3A 1FSBA 1AUTL 2BO2A 2XC0L 1W7XL 2DDUA 1IGXA 1ZAQA 5CISA 1CQEA 1ATEA 2EI7B 4XBMA 1Z6EL 1SZBA 1MQ5L 1KLOA 3N8WB 1WHFA 3GISX 1LMJA 2Y82B 1IQGL 2WPIE 1APQA 4NA9L 1EPGA 1NFWB 3KRKA 5F19A 3N8ZA 1PTHA 2W3KB 1IQEL 2BMGA 2BOXA 2Y7XB 5I46L 3TH3L 2XBXL 1PFXL 1YUGA 2W86A 4X8SL 4D0EA 3NT1A 2EI8B 5COXA 4M11A 4O1ZA 4NG9L 1UZJA 3P5BL 1OB1C 2RNLA 3SOBB 1G2MB 2OYUP 1YO8A 1DVAL 2P26A 4Y71B 4CUEA 2PUQL 4CUDA 5EGMB 2P3FN 4XL1A 3CENL 4A7IA 1B9WA 5JVZA 2I9BA 2UWLB 4Y76B 2H9EL 1HREA 1WHEA 1IQLL 4XLWA 1HAFA 1COUA 1KSNB 2W2QE 1XKBA 4CSYA 2RHPA 1FE2A 2J95B 1N7DA 5E8DA 2W26B 3N8YA 1ADXA 3HS7A 1IQNL 2P95L 3M37L 2BOUA 1P9JA 4OTYA 5F1AA 1IVOC 3ENSA 3NTGA 1CVUA 3SOQA 3IITB 1UZKA 4ZXXL 1KIGL 6COXA 1BF9A 2B7DL 5IKRA 5KIRA 3Q3KB 5JBCE 2VJ3A 3V65B 2J2UB 1K37A 4AQTA 4NGAL 1DX5I 1Z6CA 3TK6B 2FD6A 1M1XB 4O02B 1HRFA 1IQJL 1IQKL 2ADXA 3ZYJB 2PHBB 1EPJA 1TOZA 1EBVA 3HO5A 2XC4L 4BTUA 3CS7L 3ZYGA 3ELAL 1F0SB 2KL7A 1KLJL 2MGPA 2WPJE 1HJ7A 1IOXA 3KQCL 1F0RB 1G1QA 2BQWA 1YGCL 3MQEA 2J94B 1W8BL 3N8XA 1I0UA 1CCFA 1APOA 1PRHA 4Z6AL 2KB9A 4Z0KB 2Y81B 4D90A 2BQ6A 1LPGA 4X8VL 2WG3C 3TZIA 4ZH8B 4ZAEB 1EAIC 3H5CB 1U67A 2P3TA 1LPZA 4ISIL 4MMXB 4FM5A 4TGFA 2BOHA 2WFXB 1EQHA 1UZPA 2UWPB 2G00L 3CA7A 4E1GA 2WYJB 1F7MA 1EQGA 1TPGA 1L3YA 5IKQA 1HZ8A 1DDXA 3FBYA 1F7EA 1V3XB 3U7UG 4RRYA 1G2LB 3M36L 1P0SL 5JB8E 2EI6B 2VWNL 5JVYA 2NPRA 3SW2A 1LPKA 1K36A 1GK5A 3N8YB 2OYEP 3OLUA 3KQDL 3QH0A 2XBWL 4PH9A 3C9AC 4ISHL 1MQ6L 1IQHL 1NT0A 3K9XA 2M74A 4C16A 1A3PA 1HCGB 3LC3B 5JBBE 1KLIL 1IGZA 1XKAL 1NFUB 2TGFA 3HO4A 2Y38A 1FF7A 1NQLB 1J9CL 1HT8A 4RRXA 2F9BL 1NFYB 1CEJA 4BXWA 2P3FL 4ZXYL 1HX2A 1IJQA 2K2SB 5FDQA 3CFWA 3LIWB 3TK5B 3F6UL 2Y5HL 1ATAA 2XBVL 1FAKL 1WU1B 3QCWA 2J4IB 1NFXB 4BDWA 4BDXA 3QMOA 2W2PE 1FJSL 3DEMA 3HPTA 2P28B 2UWOB 1QFKL 4RRWA 2PR3B 4LORA 3ZYIB 2I9AA 2P94L 1CX2A 1TLEA 2Y80B 2W2NE 3NTBA 3V64C 3ASIA 4JZEL 1DQBA 5L2YL 3N8VA 2FZZL 4X8UL 1YUFA 4BTIA 4JZFL 4RRZA 3LN0A 2GD4A 2WFTA 3KQEL 2VVVL 1XDTR 1Q4GA 1C5MF 2FLBL 3HS5A 1IP0A 2BQ7A 2Y7ZB 2VH0B 3OLTA 3F1SB 3R05A 1EPHA 3SOVA 1IQML 5CKQA 1FAXL 2WPLE 4CUFA 2XC5L 4ZHAB 3POYA 4BXSA 4LMFA 1EZQB 1UZQA 1N1IA 1CVWL 1U8CB 2P3UA 3LN1A 5CKMA 2RA0L 3IJEB 4JYVL 1L5GB 2XBYL 5JW1A 3EGFA 3PGHA 3RR3A 2W3IB 2VWMK 2W2ME 5L30L 2WYGB 3TGFA 4Y7AB 2BOKL 1LQDA 4YT6L 2FLRL 1PGEA 2WPME 1HAEA 3LC5B 4MMZB 4D0FA 5JB9E 3KL6B 1FFMA 4YZUB 3FCSB 2VWLL 2Y5GL 1G1TA 1G1RA 5L2ZL 4YT7L 2J38B 5IKVA 1URKA 1HT5A 3KQBL 2BZ6L 3MDLA 3U73A 4COXA 4M10A 2Y5FL 2WPHE 1EGFA 4RUTA 4OTJA 4RS0A 4Y6DB 3FFGL 2P16L 1CCVA 1EMNA 2D1JB 3NJPC 2MHPA 1MOXC 1NZIA 4Y79B 2J34B 2W2OE 2P93L 1DIYA 1JV2B 3GCWE 1ATDA 1YUKB 2Q1JB 4BTTA 3BT1A 5KN5C 1IQIL 2FLGA 1G1SA 1O5DL 1IQFL 4MMYB 1NPEB 1JBUL 2AYLA 1XFEA 3BPSE 3LAQA 4JZDL 2WG4B 5IKTA 2VH6B 1PXXA 2MGRA 2VVUL 1EPIA 1RFNB 3Q7DA 1EMOA 2YGOA 4Z0LA
chains in the Genus database with same CATH superfamily
3TBDA 2KV4A 2VWOL 2VVCK 5JBAE 2CJIB 2YGPA 5K0HB 1JL9A 4A94C 3LTGD 5CKNA 3KK6A 3N8WA 1IOEL 4GU3A 4X8TL 4JYUL 3BT2A 2WPKE 2JKHL 4G1MB 3HS6A 4Y7BB 1ATBA 1X7AL 3GCXE 3LTFB 3KCGL 2K2TA 3HO3A 1FSBA 1AUTL 2BO2A 2XC0L 1W7XL 2DDUA 1IGXA 1ZAQA 5CISA 1CQEA 1ATEA 2EI7B 4XBMA 1Z6EL 1SZBA 1MQ5L 1KLOA 3N8WB 1WHFA 3GISX 1LMJA 2Y82B 1IQGL 2WPIE 1APQA 4NA9L 1EPGA 1NFWB 3KRKA 5F19A 3N8ZA 1PTHA 2W3KB 1IQEL 2BMGA 2BOXA 2Y7XB 5I46L 3TH3L 2XBXL 1PFXL 1YUGA 2W86A 4X8SL 4D0EA 3NT1A 2EI8B 5COXA 4M11A 4O1ZA 4NG9L 1UZJA 3P5BL 1OB1C 2RNLA 3SOBB 1G2MB 2OYUP 1YO8A 1DVAL 2P26A 4Y71B 4CUEA 2PUQL 4CUDA 5EGMB 2P3FN 4XL1A 3CENL 4A7IA 1B9WA 5JVZA 2I9BA 2UWLB 4Y76B 2H9EL 1HREA 1WHEA 1IQLL 4XLWA 2HORA 1HAFA 1COUA 1KSNB 2W2QE 4GU4A 1XKBA 4CSYA 2RHPA 1FE2A 2J95B 1N7DA 5E8DA 2W26B 3N8YA 1ADXA 3HS7A 1IQNL 2P95L 3M37L 2BOUA 1P9JA 4OTYA 5F1AA 1IVOC 3ENSA 3NTGA 1CVUA 3SOQA 3IITB 1LK9A 1UZKA 4ZXXL 1KIGL 6COXA 1BF9A 2B7DL 5IKRA 5KIRA 3Q3KB 5JBCE 2VJ3A 2JJLA 3V65B 2J2UB 1K37A 4AQTA 4NGAL 1DX5I 1Z6CA 3TK6B 2FD6A 1M1XB 4O02B 1HRFA 1IQJL 1IQKL 2ADXA 3ZYJB 2PHBB 1EPJA 1TOZA 1EBVA 3HO5A 2XC4L 4BTUA 3CS7L 3ZYGA 3ELAL 1F0SB 2KL7A 1KLJL 2MGPA 2WZPP 2WPJE 1HJ7A 1IOXA 3KQCL 1F0RB 1G1QA 2BQWA 1YGCL 3MQEA 2J94B 1W8BL 3N8XA 1I0UA 1CCFA 1APOA 1PRHA 4Z6AL 2KB9A 1V1HA 4Z0KB 2Y81B 4D90A 2BQ6A 1LPGA 4X8VL 2WG3C 3TZIA 4ZH8B 4ZAEB 1EAIC 3H5CB 1U67A 2P3TA 1LPZA 4ISIL 4FM5A 4MMXB 4TGFA 2BOHA 2WFXB 1EQHA 1UZPA 1LMMA 2KNIA 2UWPB 2G00L 3CA7A 4E1GA 2WYJB 1F7MA 1EQGA 1TPGA 2BT8A 1L3YA 1QIUA 5IKQA 1HZ8A 2YGQA 1DDXA 3FBYA 1F7EA 1V3XB 3U7UG 1KKEA 4RRYA 1G2LB 3M36L 1P0SL 5JB8E 2EI6B 2VWNL 5JVYA 2NPRA 3SW2A 1LPKA 1K36A 1GK5A 3N8YB 2OYEP 3OLUA 3KQDL 3QH0A 2XBWL 4PH9A 3C9AC 4ISHL 1MQ6L 1IQHL 1NT0A 3K9XA 2M74A 4C16A 1A3PA 1HCGB 3LC3B 5JBBE 1KLIL 1IGZA 1XKAL 1NFUB 2TGFA 3HO4A 2Y38A 1FF7A 1NQLB 1J9CL 1HT8A 4RRXA 2F9BL 1NFYB 1CEJA 4BXWA 2P3FL 4ZXYL 1HX2A 1IJQA 2K2SB 5FDQA 3CFWA 3LIWB 3TK5B 3F6UL 2Y5HL 1ATAA 2XBVL 1FAKL 1WU1B 3QCWA 2J4IB 1NFXB 4BDWA 4BDXA 3QMOA 2W2PE 1FJSL 3DEMA 3HPTA 2P28B 2UWOB 1QFKL 4RRWA 2PR3B 4LORA 3ZYIB 2I9AA 2P94L 1CX2A 1TLEA 2Y80B 2W2NE 3NTBA 3V64C 3ASIA 4JZEL 1DQBA 2BT7A 3N8VA 5L2YL 2FZZL 4X8UL 1YUFA 4BTIA 4JZFL 4RRZA 3LN0A 2GD4A 2WFTA 3KQEL 2VVVL 1XDTR 1Q4GA 1C5MF 2FLBL 3HS5A 1IP0A 2BQ7A 2Y7ZB 2BSFA 2VH0B 3OLTA 3F1SB 3R05A 1EPHA 3SOVA 1IQML 5CKQA 1FAXL 2WPLE 4CUFA 2XC5L 4ZHAB 3POYA 4BXSA 4LMFA 1EZQB 1UZQA 1N1IA 1CVWL 1U8CB 2P3UA 3LN1A 5CKMA 2RA0L 3IJEB 4JYVL 1L5GB 2XBYL 5JW1A 3EGFA 3PGHA 3RR3A 2W3IB 2VWMK 2W2ME 5L30L 2WYGB 3TGFA 4Y7AB 2BOKL 1LQDA 4YT6L 2FLRL 1PGEA 2WPME 1HAEA 3LC5B 3S6XA 4MMZB 4D0FA 5JB9E 3KL6B 1FFMA 4YZUB 3FCSB 1V1IA 2HOXA 2VWLL 2Y5GL 1G1TA 1G1RA 5L2ZL 4YT7L 2J38B 5IKVA 1URKA 1HT5A 3KQBL 2BZ6L 3MDLA 3U73A 4COXA 2H9EC 4M10A 2Y5FL 2WPHE 1EGFA 4RUTA 4OTJA 4RS0A 4Y6DB 3FFGL 2P16L 1CCVA 1EMNA 2D1JB 3NJPC 2MHPA 1MOXC 1NZIA 4Y79B 2VRSA 2J34B 2W2OE 2P93L 1DIYA 1JV2B 3GCWE 1ATDA 1YUKB 2Q1JB 4BTTA 3BT1A 5KN5C 1IQIL 2FLGA 1G1SA 1O5DL 1IQFL 4MMYB 1NPEB 1JBUL 2AYLA 1XFEA 3BPSE 3LAQA 4JZDL 2WG4B 5IKTA 2VH6B 1PXXA 2MGRA 2VVUL 1EPIA 1RFNB 3Q7DA 1EMOA 2YGOA 4Z0LA
chains in the Genus database with same CATH topology
3TBDA 2KV4A 2VWOL 2VVCK 5JBAE 2CJIB 2YGPA 5K0HB 1JL9A 4A94C 3LTGD 5CKNA 3KK6A 3N8WA 1IOEL 4X8TL 4JYUL 3BT2A 2WPKE 2JKHL 4G1MB 3HS6A 4Y7BB 1ATBA 1X7AL 3GCXE 3LTFB 3KCGL 2K2TA 3HO3A 1FSBA 1AUTL 2BO2A 2XC0L 1W7XL 2DDUA 1IGXA 1ZAQA 5CISA 1CQEA 1ATEA 2EI7B 4XBMA 1Z6EL 1SZBA 1MQ5L 1KLOA 3N8WB 1WHFA 3GISX 1LMJA 2Y82B 1IQGL 2WPIE 1APQA 4NA9L 1EPGA 1NFWB 3KRKA 5F19A 3N8ZA 1PTHA 2W3KB 1IQEL 2BMGA 2BOXA 2Y7XB 5I46L 3TH3L 2XBXL 1PFXL 1YUGA 2W86A 4X8SL 4D0EA 3NT1A 2EI8B 5COXA 4M11A 4O1ZA 4NG9L 1UZJA 3P5BL 1OB1C 2RNLA 3SOBB 1G2MB 2OYUP 1YO8A 1DVAL 2P26A 4Y71B 4CUEA 2PUQL 4CUDA 5EGMB 2P3FN 4XL1A 3CENL 4A7IA 1B9WA 5JVZA 2I9BA 2UWLB 4Y76B 2H9EL 1HREA 1WHEA 1IQLL 4XLWA 1HAFA 1COUA 1KSNB 2W2QE 1XKBA 4CSYA 2RHPA 1FE2A 2J95B 1N7DA 5E8DA 2W26B 3N8YA 1ADXA 3HS7A 1IQNL 2P95L 3M37L 2BOUA 1P9JA 4OTYA 5F1AA 1IVOC 3ENSA 3NTGA 1CVUA 3SOQA 3IITB 1UZKA 4ZXXL 1KIGL 6COXA 1BF9A 2B7DL 5IKRA 5KIRA 3Q3KB 5JBCE 2VJ3A 3V65B 2J2UB 1K37A 4AQTA 4NGAL 1DX5I 1Z6CA 3TK6B 2FD6A 1M1XB 4O02B 1HRFA 1IQJL 1IQKL 2ADXA 3ZYJB 2PHBB 1EPJA 1TOZA 1EBVA 3HO5A 2XC4L 4BTUA 3CS7L 3ZYGA 3ELAL 1F0SB 2KL7A 1KLJL 2MGPA 2WZPP 2WPJE 1HJ7A 1IOXA 3KQCL 1F0RB 1G1QA 2BQWA 1YGCL 3MQEA 2J94B 1W8BL 3N8XA 1I0UA 1CCFA 1APOA 1PRHA 4Z6AL 2KB9A 4Z0KB 2Y81B 4D90A 2BQ6A 1LPGA 4X8VL 2WG3C 3TZIA 4ZH8B 4ZAEB 1EAIC 3H5CB 1U67A 2P3TA 1LPZA 4ISIL 4MMXB 4FM5A 4TGFA 2BOHA 2WFXB 1EQHA 1UZPA 1LMMA 2KNIA 2UWPB 2G00L 3CA7A 4E1GA 2WYJB 1F7MA 1EQGA 1TPGA 1L3YA 5IKQA 1HZ8A 2YGQA 1DDXA 3FBYA 1F7EA 1V3XB 3U7UG 4RRYA 1G2LB 3M36L 1P0SL 5JB8E 2EI6B 2VWNL 5JVYA 2NPRA 3SW2A 1LPKA 1K36A 1GK5A 3N8YB 2OYEP 3OLUA 3KQDL 3QH0A 2XBWL 4PH9A 3C9AC 4ISHL 1MQ6L 1IQHL 1NT0A 3K9XA 2M74A 4C16A 1A3PA 1HCGB 3LC3B 5JBBE 1KLIL 1IGZA 1XKAL 1NFUB 2TGFA 3HO4A 2Y38A 1FF7A 1NQLB 1J9CL 1HT8A 4RRXA 2F9BL 1NFYB 1CEJA 4BXWA 2P3FL 4ZXYL 1HX2A 1IJQA 2K2SB 5FDQA 3CFWA 3LIWB 3TK5B 3F6UL 2Y5HL 1ATAA 2XBVL 1FAKL 1WU1B 3QCWA 2J4IB 1NFXB 4BDWA 4BDXA 3QMOA 2W2PE 1FJSL 3DEMA 3HPTA 2P28B 2UWOB 1QFKL 4RRWA 2PR3B 4LORA 3ZYIB 2I9AA 2P94L 1CX2A 1TLEA 2Y80B 2W2NE 3NTBA 3V64C 3ASIA 4JZEL 1DQBA 5L2YL 3N8VA 2FZZL 4X8UL 1YUFA 4BTIA 4JZFL 4RRZA 3LN0A 2GD4A 2WFTA 3KQEL 2VVVL 1XDTR 1Q4GA 1C5MF 2FLBL 3HS5A 1IP0A 2BQ7A 2Y7ZB 2VH0B 3OLTA 3F1SB 3R05A 1EPHA 3SOVA 1IQML 5CKQA 1FAXL 2WPLE 4CUFA 2XC5L 4ZHAB 3POYA 4BXSA 4LMFA 1EZQB 1UZQA 1N1IA 1CVWL 1U8CB 2P3UA 3LN1A 5CKMA 2RA0L 3IJEB 4JYVL 1L5GB 2XBYL 5JW1A 3EGFA 3PGHA 3RR3A 2W3IB 2VWMK 2W2ME 5L30L 2WYGB 3TGFA 4Y7AB 2BOKL 1LQDA 4YT6L 2FLRL 1PGEA 2WPME 1HAEA 3LC5B 3S6XA 4MMZB 4D0FA 5JB9E 3KL6B 1FFMA 4YZUB 3FCSB 2VWLL 2Y5GL 1G1TA 1G1RA 5L2ZL 4YT7L 2J38B 5IKVA 1URKA 1HT5A 3KQBL 2BZ6L 3MDLA 3U73A 4COXA 2H9EC 4M10A 2Y5FL 2WPHE 1EGFA 4RUTA 4OTJA 4RS0A 4Y6DB 3FFGL 2P16L 1CCVA 1EMNA 2D1JB 3NJPC 2MHPA 1MOXC 1NZIA 4Y79B 2J34B 2W2OE 2P93L 1DIYA 1JV2B 3GCWE 1ATDA 1YUKB 2Q1JB 4BTTA 3BT1A 5KN5C 1IQIL 2FLGA 1G1SA 1O5DL 1IQFL 4MMYB 1NPEB 1JBUL 2AYLA 1XFEA 3BPSE 3LAQA 4JZDL 2WG4B 5IKTA 2VH6B 1PXXA 2MGRA 2VVUL 1EPIA 1RFNB 3Q7DA 1EMOA 2YGOA 4Z0LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TBD A;  2KV4 A;  2VWO L;  2VVC K;  5JBA E;  2CJI B;  2YGP A;  5K0H B;  1JL9 A;  3LTG D;  5CKN A;  3KK6 A;  3N8W A;  1IOE L;  4X8T L;  4JYU L;  3BT2 A;  2WPK E;  2JKH L;  4G1M B;  3HS6 A;  4Y7B B;  1ATB A;  1X7A L;  3GCX E;  3LTF B;  3KCG L;  2K2T A;  3HO3 A;  1FSB A;  1AUT L;  2BO2 A;  2XC0 L;  1W7X L;  2DDU A;  1IGX A;  1ZAQ A;  5CIS A;  1CQE A;  1ATE A;  2EI7 B;  4XBM A;  1Z6E L;  1SZB A;  1MQ5 L;  1KLO A;  3N8W B;  1WHF A;  3GIS X;  1LMJ A;  2Y82 B;  1IQG L;  2WPI E;  1APQ A;  4NA9 L;  1EPG A;  1NFW B;  3KRK A;  5F19 A;  3N8Z A;  1PTH A;  2W3K B;  1IQE L;  2BMG A;  2BOX A;  2Y7X B;  5I46 L;  3TH3 L;  2XBX L;  1PFX L;  1YUG A;  2W86 A;  4X8S L;  4D0E A;  3NT1 A;  2EI8 B;  5COX A;  4M11 A;  4O1Z A;  4NG9 L;  1UZJ A;  3P5B L;  1OB1 C;  2RNL A;  3SOB B;  1G2M B;  2OYU P;  1YO8 A;  1DVA L;  2P26 A;  4Y71 B;  4CUE A;  2PUQ L;  4CUD A;  5EGM B;  2P3F N;  4XL1 A;  3CEN L;  4A7I A;  1B9W A;  5JVZ A;  2I9B A;  2UWL B;  4Y76 B;  2H9E L;  1HRE A;  1WHE A;  1IQL L;  4XLW A;  1HAF A;  1COU A;  1KSN B;  2W2Q E;  1XKB A;  4CSY A;  2RHP A;  1FE2 A;  2J95 B;  1N7D A;  5E8D A;  2W26 B;  3N8Y A;  1ADX A;  3HS7 A;  1IQN L;  2P95 L;  3M37 L;  2BOU A;  1P9J A;  4OTY A;  5F1A A;  1IVO C;  3ENS A;  3NTG A;  1CVU A;  3SOQ A;  3IIT B;  1UZK A;  4ZXX L;  1KIG L;  6COX A;  1BF9 A;  2B7D L;  5IKR A;  5KIR A;  3Q3K B;  5JBC E;  2VJ3 A;  3V65 B;  2J2U B;  1K37 A;  4AQT A;  4NGA L;  1DX5 I;  1Z6C A;  3TK6 B;  2FD6 A;  1M1X B;  4O02 B;  1HRF A;  1IQJ L;  1IQK L;  2ADX A;  3ZYJ B;  2PHB B;  1EPJ A;  1TOZ A;  1EBV A;  3HO5 A;  2XC4 L;  4BTU A;  3CS7 L;  3ZYG A;  3ELA L;  1F0S B;  2KL7 A;  1KLJ L;  2MGP A;  2WPJ E;  1HJ7 A;  1IOX A;  3KQC L;  1F0R B;  1G1Q A;  2BQW A;  1YGC L;  3MQE A;  2J94 B;  1W8B L;  3N8X A;  1I0U A;  1CCF A;  1APO A;  1PRH A;  4Z6A L;  2KB9 A;  4Z0K B;  2Y81 B;  4D90 A;  2BQ6 A;  1LPG A;  4X8V L;  2WG3 C;  3TZI A;  4ZH8 B;  4ZAE B;  1EAI C;  3H5C B;  1U67 A;  2P3T A;  1LPZ A;  4ISI L;  4MMX B;  4FM5 A;  4TGF A;  2BOH A;  2WFX B;  1EQH A;  1UZP A;  2UWP B;  2G00 L;  3CA7 A;  4E1G A;  2WYJ B;  1F7M A;  1EQG A;  1TPG A;  1L3Y A;  5IKQ A;  1HZ8 A;  1DDX A;  3FBY A;  1F7E A;  1V3X B;  3U7U G;  4RRY A;  1G2L B;  3M36 L;  1P0S L;  5JB8 E;  2EI6 B;  2VWN L;  5JVY A;  2NPR A;  3SW2 A;  1LPK A;  1K36 A;  1GK5 A;  3N8Y B;  2OYE P;  3OLU A;  3KQD L;  3QH0 A;  2XBW L;  4PH9 A;  3C9A C;  4ISH L;  1MQ6 L;  1IQH L;  1NT0 A;  3K9X A;  2M74 A;  4C16 A;  1A3P A;  1HCG B;  3LC3 B;  5JBB E;  1KLI L;  1IGZ A;  1XKA L;  1NFU B;  2TGF A;  3HO4 A;  2Y38 A;  1FF7 A;  1NQL B;  1J9C L;  1HT8 A;  4RRX A;  2F9B L;  1NFY B;  1CEJ A;  4BXW A;  2P3F L;  4ZXY L;  1HX2 A;  1IJQ A;  2K2S B;  5FDQ A;  3CFW A;  3LIW B;  3TK5 B;  3F6U L;  2Y5H L;  1ATA A;  2XBV L;  1FAK L;  1WU1 B;  3QCW A;  2J4I B;  1NFX B;  4BDW A;  4BDX A;  3QMO A;  2W2P E;  1FJS L;  3DEM A;  3HPT A;  2P28 B;  2UWO B;  1QFK L;  4RRW A;  2PR3 B;  4LOR A;  3ZYI B;  2I9A A;  2P94 L;  1CX2 A;  1TLE A;  2Y80 B;  2W2N E;  3NTB A;  3V64 C;  3ASI A;  4JZE L;  1DQB A;  5L2Y L;  3N8V A;  2FZZ L;  4X8U L;  1YUF A;  4BTI A;  4JZF L;  4RRZ A;  3LN0 A;  2GD4 A;  2WFT A;  3KQE L;  2VVV L;  1XDT R;  1Q4G A;  1C5M F;  2FLB L;  3HS5 A;  1IP0 A;  2BQ7 A;  2Y7Z B;  2VH0 B;  3OLT A;  3F1S B;  3R05 A;  1EPH A;  3SOV A;  1IQM L;  5CKQ A;  1FAX L;  2WPL E;  4CUF A;  2XC5 L;  4ZHA B;  3POY A;  4BXS A;  4LMF A;  1EZQ B;  1UZQ A;  1N1I A;  1CVW L;  1U8C B;  2P3U A;  3LN1 A;  5CKM A;  2RA0 L;  3IJE B;  4JYV L;  1L5G B;  2XBY L;  5JW1 A;  3EGF A;  3PGH A;  3RR3 A;  2W3I B;  2VWM K;  2W2M E;  5L30 L;  2WYG B;  3TGF A;  4Y7A B;  2BOK L;  1LQD A;  4YT6 L;  2FLR L;  1PGE A;  2WPM E;  1HAE A;  3LC5 B;  4MMZ B;  4D0F A;  5JB9 E;  3KL6 B;  1FFM A;  4YZU B;  3FCS B;  2VWL L;  2Y5G L;  1G1T A;  1G1R A;  5L2Z L;  4YT7 L;  2J38 B;  5IKV A;  1URK A;  1HT5 A;  3KQB L;  2BZ6 L;  3MDL A;  3U73 A;  4COX A;  4M10 A;  2Y5F L;  2WPH E;  1EGF A;  4RUT A;  4OTJ A;  4RS0 A;  4Y6D B;  3FFG L;  2P16 L;  1CCV A;  1EMN A;  2D1J B;  3NJP C;  2MHP A;  1MOX C;  1NZI A;  4Y79 B;  2J34 B;  2W2O E;  2P93 L;  1DIY A;  1JV2 B;  3GCW E;  1ATD A;  1YUK B;  2Q1J B;  4BTT A;  3BT1 A;  5KN5 C;  1IQI L;  2FLG A;  1G1S A;  1O5D L;  1IQF L;  4MMY B;  1NPE B;  1JBU L;  2AYL A;  1XFE A;  3BPS E;  3LAQ A;  4JZD L;  2WG4 B;  5IKT A;  2VH6 B;  1PXX A;  2MGR A;  2VVU L;  1EPI A;  1RFN B;  3Q7D A;  1EMO A;  2YGO A;  4Z0L A; 
#chains in the Genus database with same CATH topology
 3TBD A;  2KV4 A;  2VWO L;  2VVC K;  5JBA E;  2CJI B;  2YGP A;  5K0H B;  1JL9 A;  4A94 C;  3LTG D;  5CKN A;  3KK6 A;  3N8W A;  1IOE L;  4GU3 A;  4X8T L;  4JYU L;  3BT2 A;  2WPK E;  2JKH L;  4G1M B;  3HS6 A;  4Y7B B;  1ATB A;  1X7A L;  3GCX E;  3LTF B;  3KCG L;  2K2T A;  3HO3 A;  1FSB A;  1AUT L;  2BO2 A;  2XC0 L;  1W7X L;  2DDU A;  1IGX A;  1ZAQ A;  5CIS A;  1CQE A;  1ATE A;  2EI7 B;  4XBM A;  1Z6E L;  1SZB A;  1MQ5 L;  1KLO A;  3N8W B;  1WHF A;  3GIS X;  1LMJ A;  2Y82 B;  1IQG L;  2WPI E;  1APQ A;  4NA9 L;  1EPG A;  1NFW B;  3KRK A;  5F19 A;  3N8Z A;  1PTH A;  2W3K B;  1IQE L;  2BMG A;  2BOX A;  2Y7X B;  5I46 L;  3TH3 L;  2XBX L;  1PFX L;  1YUG A;  2W86 A;  4X8S L;  4D0E A;  3NT1 A;  2EI8 B;  5COX A;  4M11 A;  4O1Z A;  4NG9 L;  1UZJ A;  3P5B L;  1OB1 C;  2RNL A;  3SOB B;  1G2M B;  2OYU P;  1YO8 A;  1DVA L;  2P26 A;  4Y71 B;  4CUE A;  2PUQ L;  4CUD A;  5EGM B;  2P3F N;  4XL1 A;  3CEN L;  4A7I A;  1B9W A;  5JVZ A;  2I9B A;  2UWL B;  4Y76 B;  2H9E L;  1HRE A;  1WHE A;  1IQL L;  4XLW A;  2HOR A;  1HAF A;  1COU A;  1KSN B;  2W2Q E;  4GU4 A;  1XKB A;  4CSY A;  2RHP A;  1FE2 A;  2J95 B;  1N7D A;  5E8D A;  2W26 B;  3N8Y A;  1ADX A;  3HS7 A;  1IQN L;  2P95 L;  3M37 L;  2BOU A;  1P9J A;  4OTY A;  5F1A A;  1IVO C;  3ENS A;  3NTG A;  1CVU A;  3SOQ A;  3IIT B;  1LK9 A;  1UZK A;  4ZXX L;  1KIG L;  6COX A;  1BF9 A;  2B7D L;  5IKR A;  5KIR A;  3Q3K B;  5JBC E;  2VJ3 A;  2JJL A;  3V65 B;  2J2U B;  1K37 A;  4AQT A;  4NGA L;  1DX5 I;  1Z6C A;  3TK6 B;  2FD6 A;  1M1X B;  4O02 B;  1HRF A;  1IQJ L;  1IQK L;  2ADX A;  3ZYJ B;  2PHB B;  1EPJ A;  1TOZ A;  1EBV A;  3HO5 A;  2XC4 L;  4BTU A;  3CS7 L;  3ZYG A;  3ELA L;  1F0S B;  2KL7 A;  1KLJ L;  2MGP A;  2WZP P;  2WPJ E;  1HJ7 A;  1IOX A;  3KQC L;  1F0R B;  1G1Q A;  2BQW A;  1YGC L;  3MQE A;  2J94 B;  1W8B L;  3N8X A;  1I0U A;  1CCF A;  1APO A;  1PRH A;  4Z6A L;  2KB9 A;  1V1H A;  4Z0K B;  2Y81 B;  4D90 A;  2BQ6 A;  1LPG A;  4X8V L;  2WG3 C;  3TZI A;  4ZH8 B;  4ZAE B;  1EAI C;  3H5C B;  1U67 A;  2P3T A;  1LPZ A;  4ISI L;  4FM5 A;  4MMX B;  4TGF A;  2BOH A;  2WFX B;  1EQH A;  1UZP A;  1LMM A;  2KNI A;  2UWP B;  2G00 L;  3CA7 A;  4E1G A;  2WYJ B;  1F7M A;  1EQG A;  1TPG A;  2BT8 A;  1L3Y A;  1QIU A;  5IKQ A;  1HZ8 A;  2YGQ A;  1DDX A;  3FBY A;  1F7E A;  1V3X B;  3U7U G;  1KKE A;  4RRY A;  1G2L B;  3M36 L;  1P0S L;  5JB8 E;  2EI6 B;  2VWN L;  5JVY A;  2NPR A;  3SW2 A;  1LPK A;  1K36 A;  1GK5 A;  3N8Y B;  2OYE P;  3OLU A;  3KQD L;  3QH0 A;  2XBW L;  4PH9 A;  3C9A C;  4ISH L;  1MQ6 L;  1IQH L;  1NT0 A;  3K9X A;  2M74 A;  4C16 A;  1A3P A;  1HCG B;  3LC3 B;  5JBB E;  1KLI L;  1IGZ A;  1XKA L;  1NFU B;  2TGF A;  3HO4 A;  2Y38 A;  1FF7 A;  1NQL B;  1J9C L;  1HT8 A;  4RRX A;  2F9B L;  1NFY B;  1CEJ A;  4BXW A;  2P3F L;  4ZXY L;  1HX2 A;  1IJQ A;  2K2S B;  5FDQ A;  3CFW A;  3LIW B;  3TK5 B;  3F6U L;  2Y5H L;  1ATA A;  2XBV L;  1FAK L;  1WU1 B;  3QCW A;  2J4I B;  1NFX B;  4BDW A;  4BDX A;  3QMO A;  2W2P E;  1FJS L;  3DEM A;  3HPT A;  2P28 B;  2UWO B;  1QFK L;  4RRW A;  2PR3 B;  4LOR A;  3ZYI B;  2I9A A;  2P94 L;  1CX2 A;  1TLE A;  2Y80 B;  2W2N E;  3NTB A;  3V64 C;  3ASI A;  4JZE L;  1DQB A;  2BT7 A;  3N8V A;  5L2Y L;  2FZZ L;  4X8U L;  1YUF A;  4BTI A;  4JZF L;  4RRZ A;  3LN0 A;  2GD4 A;  2WFT A;  3KQE L;  2VVV L;  1XDT R;  1Q4G A;  1C5M F;  2FLB L;  3HS5 A;  1IP0 A;  2BQ7 A;  2Y7Z B;  2BSF A;  2VH0 B;  3OLT A;  3F1S B;  3R05 A;  1EPH A;  3SOV A;  1IQM L;  5CKQ A;  1FAX L;  2WPL E;  4CUF A;  2XC5 L;  4ZHA B;  3POY A;  4BXS A;  4LMF A;  1EZQ B;  1UZQ A;  1N1I A;  1CVW L;  1U8C B;  2P3U A;  3LN1 A;  5CKM A;  2RA0 L;  3IJE B;  4JYV L;  1L5G B;  2XBY L;  5JW1 A;  3EGF A;  3PGH A;  3RR3 A;  2W3I B;  2VWM K;  2W2M E;  5L30 L;  2WYG B;  3TGF A;  4Y7A B;  2BOK L;  1LQD A;  4YT6 L;  2FLR L;  1PGE A;  2WPM E;  1HAE A;  3LC5 B;  3S6X A;  4MMZ B;  4D0F A;  5JB9 E;  3KL6 B;  1FFM A;  4YZU B;  3FCS B;  1V1I A;  2HOX A;  2VWL L;  2Y5G L;  1G1T A;  1G1R A;  5L2Z L;  4YT7 L;  2J38 B;  5IKV A;  1URK A;  1HT5 A;  3KQB L;  2BZ6 L;  3MDL A;  3U73 A;  4COX A;  2H9E C;  4M10 A;  2Y5F L;  2WPH E;  1EGF A;  4RUT A;  4OTJ A;  4RS0 A;  4Y6D B;  3FFG L;  2P16 L;  1CCV A;  1EMN A;  2D1J B;  3NJP C;  2MHP A;  1MOX C;  1NZI A;  4Y79 B;  2VRS A;  2J34 B;  2W2O E;  2P93 L;  1DIY A;  1JV2 B;  3GCW E;  1ATD A;  1YUK B;  2Q1J B;  4BTT A;  3BT1 A;  5KN5 C;  1IQI L;  2FLG A;  1G1S A;  1O5D L;  1IQF L;  4MMY B;  1NPE B;  1JBU L;  2AYL A;  1XFE A;  3BPS E;  3LAQ A;  4JZD L;  2WG4 B;  5IKT A;  2VH6 B;  1PXX A;  2MGR A;  2VVU L;  1EPI A;  1RFN B;  3Q7D A;  1EMO A;  2YGO A;  4Z0L A; 
#chains in the Genus database with same CATH homology
 3TBD A;  2KV4 A;  2VWO L;  2VVC K;  5JBA E;  2CJI B;  2YGP A;  5K0H B;  1JL9 A;  4A94 C;  3LTG D;  5CKN A;  3KK6 A;  3N8W A;  1IOE L;  4X8T L;  4JYU L;  3BT2 A;  2WPK E;  2JKH L;  4G1M B;  3HS6 A;  4Y7B B;  1ATB A;  1X7A L;  3GCX E;  3LTF B;  3KCG L;  2K2T A;  3HO3 A;  1FSB A;  1AUT L;  2BO2 A;  2XC0 L;  1W7X L;  2DDU A;  1IGX A;  1ZAQ A;  5CIS A;  1CQE A;  1ATE A;  2EI7 B;  4XBM A;  1Z6E L;  1SZB A;  1MQ5 L;  1KLO A;  3N8W B;  1WHF A;  3GIS X;  1LMJ A;  2Y82 B;  1IQG L;  2WPI E;  1APQ A;  4NA9 L;  1EPG A;  1NFW B;  3KRK A;  5F19 A;  3N8Z A;  1PTH A;  2W3K B;  1IQE L;  2BMG A;  2BOX A;  2Y7X B;  5I46 L;  3TH3 L;  2XBX L;  1PFX L;  1YUG A;  2W86 A;  4X8S L;  4D0E A;  3NT1 A;  2EI8 B;  5COX A;  4M11 A;  4O1Z A;  4NG9 L;  1UZJ A;  3P5B L;  1OB1 C;  2RNL A;  3SOB B;  1G2M B;  2OYU P;  1YO8 A;  1DVA L;  2P26 A;  4Y71 B;  4CUE A;  2PUQ L;  4CUD A;  5EGM B;  2P3F N;  4XL1 A;  3CEN L;  4A7I A;  1B9W A;  5JVZ A;  2I9B A;  2UWL B;  4Y76 B;  2H9E L;  1HRE A;  1WHE A;  1IQL L;  4XLW A;  1HAF A;  1COU A;  1KSN B;  2W2Q E;  1XKB A;  4CSY A;  2RHP A;  1FE2 A;  2J95 B;  1N7D A;  5E8D A;  2W26 B;  3N8Y A;  1ADX A;  3HS7 A;  1IQN L;  2P95 L;  3M37 L;  2BOU A;  1P9J A;  4OTY A;  5F1A A;  1IVO C;  3ENS A;  3NTG A;  1CVU A;  3SOQ A;  3IIT B;  1UZK A;  4ZXX L;  1KIG L;  6COX A;  1BF9 A;  2B7D L;  5IKR A;  5KIR A;  3Q3K B;  5JBC E;  2VJ3 A;  3V65 B;  2J2U B;  1K37 A;  4AQT A;  4NGA L;  1DX5 I;  1Z6C A;  3TK6 B;  2FD6 A;  1M1X B;  4O02 B;  1HRF A;  1IQJ L;  1IQK L;  2ADX A;  3ZYJ B;  2PHB B;  1EPJ A;  1TOZ A;  1EBV A;  3HO5 A;  2XC4 L;  4BTU A;  3CS7 L;  3ZYG A;  3ELA L;  1F0S B;  2KL7 A;  1KLJ L;  2MGP A;  2WZP P;  2WPJ E;  1HJ7 A;  1IOX A;  3KQC L;  1F0R B;  1G1Q A;  2BQW A;  1YGC L;  3MQE A;  2J94 B;  1W8B L;  3N8X A;  1I0U A;  1CCF A;  1APO A;  1PRH A;  4Z6A L;  2KB9 A;  4Z0K B;  2Y81 B;  4D90 A;  2BQ6 A;  1LPG A;  4X8V L;  2WG3 C;  3TZI A;  4ZH8 B;  4ZAE B;  1EAI C;  3H5C B;  1U67 A;  2P3T A;  1LPZ A;  4ISI L;  4MMX B;  4FM5 A;  4TGF A;  2BOH A;  2WFX B;  1EQH A;  1UZP A;  1LMM A;  2KNI A;  2UWP B;  2G00 L;  3CA7 A;  4E1G A;  2WYJ B;  1F7M A;  1EQG A;  1TPG A;  1L3Y A;  5IKQ A;  1HZ8 A;  2YGQ A;  1DDX A;  3FBY A;  1F7E A;  1V3X B;  3U7U G;  4RRY A;  1G2L B;  3M36 L;  1P0S L;  5JB8 E;  2EI6 B;  2VWN L;  5JVY A;  2NPR A;  3SW2 A;  1LPK A;  1K36 A;  1GK5 A;  3N8Y B;  2OYE P;  3OLU A;  3KQD L;  3QH0 A;  2XBW L;  4PH9 A;  3C9A C;  4ISH L;  1MQ6 L;  1IQH L;  1NT0 A;  3K9X A;  2M74 A;  4C16 A;  1A3P A;  1HCG B;  3LC3 B;  5JBB E;  1KLI L;  1IGZ A;  1XKA L;  1NFU B;  2TGF A;  3HO4 A;  2Y38 A;  1FF7 A;  1NQL B;  1J9C L;  1HT8 A;  4RRX A;  2F9B L;  1NFY B;  1CEJ A;  4BXW A;  2P3F L;  4ZXY L;  1HX2 A;  1IJQ A;  2K2S B;  5FDQ A;  3CFW A;  3LIW B;  3TK5 B;  3F6U L;  2Y5H L;  1ATA A;  2XBV L;  1FAK L;  1WU1 B;  3QCW A;  2J4I B;  1NFX B;  4BDW A;  4BDX A;  3QMO A;  2W2P E;  1FJS L;  3DEM A;  3HPT A;  2P28 B;  2UWO B;  1QFK L;  4RRW A;  2PR3 B;  4LOR A;  3ZYI B;  2I9A A;  2P94 L;  1CX2 A;  1TLE A;  2Y80 B;  2W2N E;  3NTB A;  3V64 C;  3ASI A;  4JZE L;  1DQB A;  5L2Y L;  3N8V A;  2FZZ L;  4X8U L;  1YUF A;  4BTI A;  4JZF L;  4RRZ A;  3LN0 A;  2GD4 A;  2WFT A;  3KQE L;  2VVV L;  1XDT R;  1Q4G A;  1C5M F;  2FLB L;  3HS5 A;  1IP0 A;  2BQ7 A;  2Y7Z B;  2VH0 B;  3OLT A;  3F1S B;  3R05 A;  1EPH A;  3SOV A;  1IQM L;  5CKQ A;  1FAX L;  2WPL E;  4CUF A;  2XC5 L;  4ZHA B;  3POY A;  4BXS A;  4LMF A;  1EZQ B;  1UZQ A;  1N1I A;  1CVW L;  1U8C B;  2P3U A;  3LN1 A;  5CKM A;  2RA0 L;  3IJE B;  4JYV L;  1L5G B;  2XBY L;  5JW1 A;  3EGF A;  3PGH A;  3RR3 A;  2W3I B;  2VWM K;  2W2M E;  5L30 L;  2WYG B;  3TGF A;  4Y7A B;  2BOK L;  1LQD A;  4YT6 L;  2FLR L;  1PGE A;  2WPM E;  1HAE A;  3LC5 B;  3S6X A;  4MMZ B;  4D0F A;  5JB9 E;  3KL6 B;  1FFM A;  4YZU B;  3FCS B;  2VWL L;  2Y5G L;  1G1T A;  1G1R A;  5L2Z L;  4YT7 L;  2J38 B;  5IKV A;  1URK A;  1HT5 A;  3KQB L;  2BZ6 L;  3MDL A;  3U73 A;  4COX A;  2H9E C;  4M10 A;  2Y5F L;  2WPH E;  1EGF A;  4RUT A;  4OTJ A;  4RS0 A;  4Y6D B;  3FFG L;  2P16 L;  1CCV A;  1EMN A;  2D1J B;  3NJP C;  2MHP A;  1MOX C;  1NZI A;  4Y79 B;  2J34 B;  2W2O E;  2P93 L;  1DIY A;  1JV2 B;  3GCW E;  1ATD A;  1YUK B;  2Q1J B;  4BTT A;  3BT1 A;  5KN5 C;  1IQI L;  2FLG A;  1G1S A;  1O5D L;  1IQF L;  4MMY B;  1NPE B;  1JBU L;  2AYL A;  1XFE A;  3BPS E;  3LAQ A;  4JZD L;  2WG4 B;  5IKT A;  2VH6 B;  1PXX A;  2MGR A;  2VVU L;  1EPI A;  1RFN B;  3Q7D A;  1EMO A;  2YGO A;  4Z0L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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