2PHEA

Model for vp16 binding to pc4
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
66
structure length
66
Chain Sequence
AMFQIGKMRYVSVRDFKGKVLIDIREYWMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription
molecule keywords TRANSCRIPTIONAL COACTIVATOR PC4
publication title Structural Properties of the Promiscuous VP16 Activation Domain
pubmed doi rcsb
source organism Homo sapiens
total genus 14
structure length 66
sequence length 66
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-04-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02229 PC4 Transcriptional Coactivator p15 (PC4)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.31.10 Mainly Beta Roll Transcriptional Co-activator pc4; Chain A Transcriptional Coactivator Pc4; Chain A 2pheA00
4KOQA 1PCFA 3N1KA 3N1LA 4KOOA 2IT9A 4USGA 3R9YA 4KOPA 2NVNA 3RA0A 4BHMA 3N1IA 4AGHA 3R9ZA 3N1JA 2PHEA 4BG7A 1L3AA 3N1HA 2C62A
chains in the Genus database with same CATH superfamily
3OBHA 4KOQA 1PCFA 3N1KA 4BODA 2M4FA 4KOOA 3N1LA 4BOBA 4BXMA 2GJEA 2IT9A 5FGPA 2GIAA 4USGA 3R9YA 4BF3A 3CM1A 4KOPA 2GIDB 2NVNA 3RA0A 4BHMA 3N1IA 3MTVA 4AGHA 3K44A 2GIDA 3R9ZA 3N1JA 2PHEA 2GJED 4BG7A 1L3AA 3N1HA 2C62A 4J38A 2GIAB
chains in the Genus database with same CATH topology
4KOQA 1PCFA 3N1KA 3N1LA 4KOOA 2IT9A 4USGA 3R9YA 4KOPA 2NVNA 3RA0A 4BHMA 3N1IA 4AGHA 3R9ZA 3N1JA 2PHEA 4BG7A 1L3AA 3N1HA 2C62A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KOQ A;  1PCF A;  3N1K A;  3N1L A;  4KOO A;  2IT9 A;  4USG A;  3R9Y A;  4KOP A;  2NVN A;  3RA0 A;  4BHM A;  3N1I A;  4AGH A;  3R9Z A;  3N1J A;  2PHE A;  4BG7 A;  1L3A A;  3N1H A;  2C62 A; 
#chains in the Genus database with same CATH topology
 3OBH A;  4KOQ A;  1PCF A;  3N1K A;  4BOD A;  2M4F A;  4KOO A;  3N1L A;  4BOB A;  4BXM A;  2GJE A;  2IT9 A;  5FGP A;  2GIA A;  4USG A;  3R9Y A;  4BF3 A;  3CM1 A;  4KOP A;  2GID B;  2NVN A;  3RA0 A;  4BHM A;  3N1I A;  3MTV A;  4AGH A;  3K44 A;  2GID A;  3R9Z A;  3N1J A;  2PHE A;  2GJE D;  4BG7 A;  1L3A A;  3N1H A;  2C62 A;  4J38 A;  2GIA B; 
#chains in the Genus database with same CATH homology
 4KOQ A;  1PCF A;  3N1K A;  3N1L A;  4KOO A;  2IT9 A;  4USG A;  3R9Y A;  4KOP A;  2NVN A;  3RA0 A;  4BHM A;  3N1I A;  4AGH A;  3R9Z A;  3N1J A;  2PHE A;  4BG7 A;  1L3A A;  3N1H A;  2C62 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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