2PQ9A

E. coli epsps liganded with (r)-difluoromethyl tetrahedral reaction intermediate analog
Total Genus 153
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
153
sequence length
427
structure length
427
Chain Sequence
MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTALGVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Differential inhibition of class I and class II 5-enolpyruvylshikimate-3-phosphate synthases by tetrahedral reaction intermediate analogues.
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords 3-phosphoshikimate 1-carboxyvinyltransferase
total genus 153
structure length 427
sequence length 427
ec nomenclature ec 2.5.1.19: 3-phosphoshikimate 1-carboxyvinyltransferase.
pdb deposition date 2007-05-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00275 EPSP_synthase EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.65.10.10 Alpha Beta Alpha-beta prism UDP-n-acetylglucosamine1-carboxyvinyl-transferase; Chain Enolpyruvate transferase domain 2pq9A02
3.65.10.10 Alpha Beta Alpha-beta prism UDP-n-acetylglucosamine1-carboxyvinyl-transferase; Chain Enolpyruvate transferase domain 2pq9A01
2O0BA 3UPKA 3SG1A 3ROIA 1Q36A 3V4TA 2QFSA 2GGDA 1EJDA 2O0ZA 3FJXA 3KQJA 2BJBA 1RF6A 1P89A 4ZNDA 2GG4A 4R7UA 4E7DA 5BQ2A 3VCYA 3SWIA 1RF4A 4E7GA 3SPBA 1P88A 3KR6A 1EJCA 1EYNA 5BUFA 2YVWA 2Z2CA 1X8TA 1RF5A 2QFQA 3TI2A 2RL1A 2PQDA 2O0XA 2O0DA 4EIIA 2PQCA 1G6SA 3SWQA 3LTHA 2PQ9A 3SWGA 1RYWA 1NAWA 1MI4A 3ZH4A 3SLHA 1Q3GA 1UAEA 1YBGA 3ISSA 3SWDA 2O15A 4FQDA 3FK1A 2PQBA 3RMTA 3FK0A 1G6TA 3SWEA 2O0EA 3NVSA 4E7CA 1X8RA 5BS5A 2QFTA 3KQAA 4EGRA 2AA9A 2GG6A 4E7FA 3R38A 2RL2A 2GGAA 5U4HA 3ZH3A 3SWAA 4E7BA 4N3PA 4GFPA 3TR1A 2AAYA 1A2NA 4E7EA 2QFUA 3FJZA 1DLGA 3V5VA 3SU9A
chains in the Genus database with same CATH superfamily
2O0BA 3UPKA 3SG1A 3ROIA 1Q36A 3V4TA 2QFSA 2GGDA 1EJDA 2O0ZA 3FJXA 3KQJA 2BJBA 1RF6A 1P89A 4ZNDA 2GG4A 4R7UA 4E7DA 5BQ2A 3VCYA 3SWIA 1RF4A 4E7GA 3SPBA 1P88A 3KR6A 1EJCA 1EYNA 5BUFA 2YVWA 2Z2CA 3TUTA 1X8TA 1RF5A 2QFQA 3TI2A 2RL1A 2PQDA 2O0XA 2O0DA 4EIIA 2PQCA 1G6SA 3SWQA 3LTHA 2PQ9A 3SWGA 1RYWA 1NAWA 1MI4A 4O89A 3ZH4A 3SLHA 1Q3GA 1UAEA 1YBGA 3ISSA 3SWDA 2O15A 3TW3A 3TV1A 4FQDA 3TUXA 3FK1A 2PQBA 3RMTA 3FK0A 1G6TA 3SWEA 2O0EA 3NVSA 4E7CA 1X8RA 4CLQA 3KGDA 5BS5A 2QFTA 3KQAA 4EGRA 2AA9A 1QMIA 2GG6A 4E7FA 1QMHA 3R38A 2RL2A 2GGAA 5U4HA 3ZH3A 3SWAA 4E7BA 4N3PA 3PQVA 4GFPA 3TR1A 2AAYA 1A2NA 4E7EA 2QFUA 3FJZA 4O8JA 1DLGA 3V5VA 3SU9A
chains in the Genus database with same CATH topology
2O0BA 3UPKA 3SG1A 3ROIA 1Q36A 3V4TA 2QFSA 2GGDA 1EJDA 2O0ZA 3FJXA 3KQJA 2BJBA 1RF6A 1P89A 4ZNDA 2GG4A 4R7UA 4E7DA 5BQ2A 3VCYA 3SWIA 1RF4A 4E7GA 3SPBA 1P88A 3KR6A 1EJCA 1EYNA 5BUFA 2YVWA 2Z2CA 1X8TA 1RF5A 2QFQA 3TI2A 2RL1A 2PQDA 2O0XA 2O0DA 4EIIA 2PQCA 1G6SA 3SWQA 3LTHA 2PQ9A 3SWGA 1RYWA 1NAWA 1MI4A 3ZH4A 3SLHA 1Q3GA 1UAEA 1YBGA 3ISSA 3SWDA 2O15A 4FQDA 3FK1A 2PQBA 3RMTA 3FK0A 1G6TA 3SWEA 2O0EA 3NVSA 4E7CA 1X8RA 5BS5A 2QFTA 3KQAA 4EGRA 2AA9A 2GG6A 4E7FA 3R38A 2RL2A 2GGAA 5U4HA 3ZH3A 3SWAA 4E7BA 4N3PA 4GFPA 3TR1A 2AAYA 1A2NA 4E7EA 2QFUA 3FJZA 1DLGA 3V5VA 3SU9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2O0B A;  3UPK A;  3SG1 A;  3ROI A;  1Q36 A;  3V4T A;  2QFS A;  2GGD A;  1EJD A;  2O0Z A;  3FJX A;  3KQJ A;  2BJB A;  1RF6 A;  1P89 A;  4ZND A;  2GG4 A;  4R7U A;  4E7D A;  5BQ2 A;  3VCY A;  3SWI A;  1RF4 A;  4E7G A;  3SPB A;  1P88 A;  3KR6 A;  1EJC A;  1EYN A;  5BUF A;  2YVW A;  2Z2C A;  1X8T A;  1RF5 A;  2QFQ A;  3TI2 A;  2RL1 A;  2PQD A;  2O0X A;  2O0D A;  4EII A;  2PQC A;  1G6S A;  3SWQ A;  3LTH A;  2PQ9 A;  3SWG A;  1RYW A;  1NAW A;  1MI4 A;  3ZH4 A;  3SLH A;  1Q3G A;  1UAE A;  1YBG A;  3ISS A;  3SWD A;  2O15 A;  4FQD A;  3FK1 A;  2PQB A;  3RMT A;  3FK0 A;  1G6T A;  3SWE A;  2O0E A;  3NVS A;  4E7C A;  1X8R A;  5BS5 A;  2QFT A;  3KQA A;  4EGR A;  2AA9 A;  2GG6 A;  4E7F A;  3R38 A;  2RL2 A;  2GGA A;  5U4H A;  3ZH3 A;  3SWA A;  4E7B A;  4N3P A;  4GFP A;  3TR1 A;  2AAY A;  1A2N A;  4E7E A;  2QFU A;  3FJZ A;  1DLG A;  3V5V A;  3SU9 A; 
#chains in the Genus database with same CATH topology
 2O0B A;  3UPK A;  3SG1 A;  3ROI A;  1Q36 A;  3V4T A;  2QFS A;  2GGD A;  1EJD A;  2O0Z A;  3FJX A;  3KQJ A;  2BJB A;  1RF6 A;  1P89 A;  4ZND A;  2GG4 A;  4R7U A;  4E7D A;  5BQ2 A;  3VCY A;  3SWI A;  1RF4 A;  4E7G A;  3SPB A;  1P88 A;  3KR6 A;  1EJC A;  1EYN A;  5BUF A;  2YVW A;  2Z2C A;  3TUT A;  1X8T A;  1RF5 A;  2QFQ A;  3TI2 A;  2RL1 A;  2PQD A;  2O0X A;  2O0D A;  4EII A;  2PQC A;  1G6S A;  3SWQ A;  3LTH A;  2PQ9 A;  3SWG A;  1RYW A;  1NAW A;  1MI4 A;  4O89 A;  3ZH4 A;  3SLH A;  1Q3G A;  1UAE A;  1YBG A;  3ISS A;  3SWD A;  2O15 A;  3TW3 A;  3TV1 A;  4FQD A;  3TUX A;  3FK1 A;  2PQB A;  3RMT A;  3FK0 A;  1G6T A;  3SWE A;  2O0E A;  3NVS A;  4E7C A;  1X8R A;  4CLQ A;  3KGD A;  5BS5 A;  2QFT A;  3KQA A;  4EGR A;  2AA9 A;  1QMI A;  2GG6 A;  4E7F A;  1QMH A;  3R38 A;  2RL2 A;  2GGA A;  5U4H A;  3ZH3 A;  3SWA A;  4E7B A;  4N3P A;  3PQV A;  4GFP A;  3TR1 A;  2AAY A;  1A2N A;  4E7E A;  2QFU A;  3FJZ A;  4O8J A;  1DLG A;  3V5V A;  3SU9 A; 
#chains in the Genus database with same CATH homology
 2O0B A;  3UPK A;  3SG1 A;  3ROI A;  1Q36 A;  3V4T A;  2QFS A;  2GGD A;  1EJD A;  2O0Z A;  3FJX A;  3KQJ A;  2BJB A;  1RF6 A;  1P89 A;  4ZND A;  2GG4 A;  4R7U A;  4E7D A;  5BQ2 A;  3VCY A;  3SWI A;  1RF4 A;  4E7G A;  3SPB A;  1P88 A;  3KR6 A;  1EJC A;  1EYN A;  5BUF A;  2YVW A;  2Z2C A;  1X8T A;  1RF5 A;  2QFQ A;  3TI2 A;  2RL1 A;  2PQD A;  2O0X A;  2O0D A;  4EII A;  2PQC A;  1G6S A;  3SWQ A;  3LTH A;  2PQ9 A;  3SWG A;  1RYW A;  1NAW A;  1MI4 A;  3ZH4 A;  3SLH A;  1Q3G A;  1UAE A;  1YBG A;  3ISS A;  3SWD A;  2O15 A;  4FQD A;  3FK1 A;  2PQB A;  3RMT A;  3FK0 A;  1G6T A;  3SWE A;  2O0E A;  3NVS A;  4E7C A;  1X8R A;  5BS5 A;  2QFT A;  3KQA A;  4EGR A;  2AA9 A;  2GG6 A;  4E7F A;  3R38 A;  2RL2 A;  2GGA A;  5U4H A;  3ZH3 A;  3SWA A;  4E7B A;  4N3P A;  4GFP A;  3TR1 A;  2AAY A;  1A2N A;  4E7E A;  2QFU A;  3FJZ A;  1DLG A;  3V5V A;  3SU9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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