2Q19X

2-keto-3-deoxy-d-arabinonate dehydratase apo form
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
291
structure length
282
Chain Sequence
MKLFRVVKRGYYISYAILDNSTIIRLDEDPIKALMRYSENKEVLGDRVTGIDYQSLLKSFQINDIRITKPIDPPEVWGSGISYEMVAKILGKTIYEKVYDAVRPEIFFKATPNRCVGHGEAIAVRSDSEWTLPEPELAVVLDSNGKILGYTIMDDVSARDLEAENPLYLPQSKIYAGCCAFGPVIVTSDEIKNPYSLDITLKIVREGRVFFEGSVNTNKMRRKIEEQIQYLIRDNPIPDGTILTTGTAIVPGRDKGLKDEDIVEITISNIGTLITPVKKRRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
pubmed doi rcsb
source organism Sulfolobus solfataricus
molecule tags Lyase
molecule keywords 2-keto-3-deoxy-D-arabinonate dehydratase
total genus 76
structure length 282
sequence length 291
ec nomenclature ec 4.2.1.141: 2-dehydro-3-deoxy-D-arabinonate dehydratase.
pdb deposition date 2007-05-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01557 FAA_hydrolase Fumarylacetoacetate (FAA) hydrolase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.330.40 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 2q19X01
3.90.850.10 Alpha Beta Alpha-Beta Complex Fumarylacetoacetate hydrolase; domain 2 Fumarylacetoacetase-like, C-terminal domain 2q19X02
1NKQA 3LZKA 1HYOA 2DFUA 4DBHA 3S52A 4MAQA 2Q1CX 1SV6A 3R6OA 5D2IA 2Q1AX 1QQJA 5D2JA 4QKUA 1NR9A 5D2GA 3V77A 4PFZA 5D2FA 2EB5A 2HZYA 1I7OA 3RR6A 5D2KA 1WZOA 1SAWA 4DBFA 2EB6A 1QCOA 2Q1DX 3BQBA 2EB4A 1QCNA 5D2HA 2WQTA 2Q18X 1GTTA 2Q19X 3QDFA
chains in the Genus database with same CATH superfamily
2MM0A 1S3SA 5CCBA 4AS1A 3LZKA 3QWZA 1HYOA 1I9GA 3TIWA 4KDIA 4MAQA 1E32A 4CQNA 1QQJA 1CR5A 2XDPA 5D2GA 5D2FA 2EB5A 2QQRA 5FTMA 4DBFA 2EB6A 1QCOA 3QC8A 3ZJTA 1QCSA 3FPUA 3HU1A 3CF2A 1GTTA 3QDFA 5B6CA 3ZJUA 4ARCA 1R7RA 3FPTA 5EQJB 5C18A 5ERGB 2LW6A 5DYGA 3MB5A 5GLFA 5FTKA 5D6YA 2Q1CX 5D2JA 4QKUA 1WLFA 3LGAA 5FTJA 4KO8A 3LHDA 2YVLA 2Q1DX 3BQBA 1ZC1A 2PJHB 4KDLA 2QQSA 1NKQA 2PWYA 3QQ7A 2GF7A 3S52A 4KLNA 5EPPA 3HU2A 2GFAA 2Q1AX 3ZGZA 1CZ4A 4PFZA 3RR6A 2HZYA 5CCXA 1I7OA 1QCNA 5D2HA 2WQTA 2B25A 4AQ7A 5FTNA 5CD1A 4RV0A 5D6WA 3FPRA 1CZ5A 4UC4A 2KY9A 2JV2A 2DFUA 4DBHA 2MM2A 5FTLA 4KODA 5C1BA 1SV6A 5DYIA 3ZJVA 3R6OA 1O54A 2YUJA 4ARIA 5D2IA 1NR9A 3V77A 5D2KA 3HU3A 1SAWA 4FIBA 1WZOA 2EB4A 3QQ8A 1QDNA 2Q18X 5D6XA 2Q19X
chains in the Genus database with same CATH topology
2MM0A 1S3SA 5CCBA 4AS1A 3LZKA 3QWZA 1HYOA 1I9GA 3TIWA 4KDIA 4MAQA 1E32A 4CQNA 1QQJA 1CR5A 2XDPA 5D2GA 5D2FA 2EB5A 2QQRA 5FTMA 4DBFA 2EB6A 1QCOA 3QC8A 3ZJTA 1QCSA 3FPUA 3HU1A 3CF2A 1GTTA 3QDFA 5B6CA 3ZJUA 4ARCA 1R7RA 3FPTA 5EQJB 5C18A 5ERGB 2LW6A 5DYGA 3MB5A 5GLFA 5FTKA 5D6YA 2Q1CX 5D2JA 4QKUA 1WLFA 3LGAA 5FTJA 4KO8A 3LHDA 2YVLA 2Q1DX 3BQBA 1ZC1A 2PJHB 4KDLA 2QQSA 1NKQA 2PWYA 3QQ7A 2GF7A 3S52A 4KLNA 5EPPA 3HU2A 2GFAA 2Q1AX 3ZGZA 1CZ4A 4PFZA 3RR6A 2HZYA 5CCXA 1I7OA 1QCNA 5D2HA 2WQTA 2B25A 4AQ7A 5FTNA 5CD1A 4RV0A 5D6WA 3FPRA 1CZ5A 4UC4A 2KY9A 2JV2A 2DFUA 4DBHA 2MM2A 5FTLA 4KODA 5C1BA 1SV6A 5DYIA 3ZJVA 3R6OA 1O54A 2YUJA 4ARIA 5D2IA 1NR9A 3V77A 5D2KA 3HU3A 1SAWA 4FIBA 1WZOA 2EB4A 3QQ8A 1QDNA 2Q18X 5D6XA 2Q19X
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NKQ A;  3LZK A;  1HYO A;  2DFU A;  4DBH A;  3S52 A;  4MAQ A;  2Q1C X;  1SV6 A;  3R6O A;  5D2I A;  2Q1A X;  1QQJ A;  5D2J A;  4QKU A;  1NR9 A;  5D2G A;  3V77 A;  4PFZ A;  5D2F A;  2EB5 A;  2HZY A;  1I7O A;  3RR6 A;  5D2K A;  1WZO A;  1SAW A;  4DBF A;  2EB6 A;  1QCO A;  2Q1D X;  3BQB A;  2EB4 A;  1QCN A;  5D2H A;  2WQT A;  2Q18 X;  1GTT A;  2Q19 X;  3QDF A; 
#chains in the Genus database with same CATH topology
 2MM0 A;  1S3S A;  5CCB A;  4AS1 A;  3LZK A;  3QWZ A;  1HYO A;  1I9G A;  3TIW A;  4KDI A;  4MAQ A;  1E32 A;  4CQN A;  1QQJ A;  1CR5 A;  2XDP A;  5D2G A;  5D2F A;  2EB5 A;  2QQR A;  5FTM A;  4DBF A;  2EB6 A;  1QCO A;  3QC8 A;  3ZJT A;  1QCS A;  3FPU A;  3HU1 A;  3CF2 A;  1GTT A;  3QDF A;  5B6C A;  3ZJU A;  4ARC A;  1R7R A;  3FPT A;  5EQJ B;  5C18 A;  5ERG B;  2LW6 A;  5DYG A;  3MB5 A;  5GLF A;  5FTK A;  5D6Y A;  2Q1C X;  5D2J A;  4QKU A;  1WLF A;  3LGA A;  5FTJ A;  4KO8 A;  3LHD A;  2YVL A;  2Q1D X;  3BQB A;  1ZC1 A;  2PJH B;  4KDL A;  2QQS A;  1NKQ A;  2PWY A;  3QQ7 A;  2GF7 A;  3S52 A;  4KLN A;  5EPP A;  3HU2 A;  2GFA A;  2Q1A X;  3ZGZ A;  1CZ4 A;  4PFZ A;  3RR6 A;  2HZY A;  5CCX A;  1I7O A;  1QCN A;  5D2H A;  2WQT A;  2B25 A;  4AQ7 A;  5FTN A;  5CD1 A;  4RV0 A;  5D6W A;  3FPR A;  1CZ5 A;  4UC4 A;  2KY9 A;  2JV2 A;  2DFU A;  4DBH A;  2MM2 A;  5FTL A;  4KOD A;  5C1B A;  1SV6 A;  5DYI A;  3ZJV A;  3R6O A;  1O54 A;  2YUJ A;  4ARI A;  5D2I A;  1NR9 A;  3V77 A;  5D2K A;  3HU3 A;  1SAW A;  4FIB A;  1WZO A;  2EB4 A;  3QQ8 A;  1QDN A;  2Q18 X;  5D6X A;  2Q19 X; 
#chains in the Genus database with same CATH homology
 2MM0 A;  1S3S A;  5CCB A;  4AS1 A;  3LZK A;  3QWZ A;  1HYO A;  1I9G A;  3TIW A;  4KDI A;  4MAQ A;  1E32 A;  4CQN A;  1QQJ A;  1CR5 A;  2XDP A;  5D2G A;  5D2F A;  2EB5 A;  2QQR A;  5FTM A;  4DBF A;  2EB6 A;  1QCO A;  3QC8 A;  3ZJT A;  1QCS A;  3FPU A;  3HU1 A;  3CF2 A;  1GTT A;  3QDF A;  5B6C A;  3ZJU A;  4ARC A;  1R7R A;  3FPT A;  5EQJ B;  5C18 A;  5ERG B;  2LW6 A;  5DYG A;  3MB5 A;  5GLF A;  5FTK A;  5D6Y A;  2Q1C X;  5D2J A;  4QKU A;  1WLF A;  3LGA A;  5FTJ A;  4KO8 A;  3LHD A;  2YVL A;  2Q1D X;  3BQB A;  1ZC1 A;  2PJH B;  4KDL A;  2QQS A;  1NKQ A;  2PWY A;  3QQ7 A;  2GF7 A;  3S52 A;  4KLN A;  5EPP A;  3HU2 A;  2GFA A;  2Q1A X;  3ZGZ A;  1CZ4 A;  4PFZ A;  3RR6 A;  2HZY A;  5CCX A;  1I7O A;  1QCN A;  5D2H A;  2WQT A;  2B25 A;  4AQ7 A;  5FTN A;  5CD1 A;  4RV0 A;  5D6W A;  3FPR A;  1CZ5 A;  4UC4 A;  2KY9 A;  2JV2 A;  2DFU A;  4DBH A;  2MM2 A;  5FTL A;  4KOD A;  5C1B A;  1SV6 A;  5DYI A;  3ZJV A;  3R6O A;  1O54 A;  2YUJ A;  4ARI A;  5D2I A;  1NR9 A;  3V77 A;  5D2K A;  3HU3 A;  1SAW A;  4FIB A;  1WZO A;  2EB4 A;  3QQ8 A;  1QDN A;  2Q18 X;  5D6X A;  2Q19 X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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