2Q1AX

2-keto-3-deoxy-d-arabinonate dehydratase complexed with magnesium and 2-oxobutyrate
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
291
structure length
291
Chain Sequence
MKLFRVVKRGYYISYAILDNSTIIRLDEDPIKALMRYSENKEVLGDRVTGIDYQSLLKSFQINDIRITKPIDPPEVWGSGISYEMARERYSEENVAKILGKTIYEKVYDAVRPEIFFKATPNRCVGHGEAIAVRSDSEWTLPEPELAVVLDSNGKILGYTIMDDVSARDLEAENPLYLPQSKIYAGCCAFGPVIVTSDEIKNPYSLDITLKIVREGRVFFEGSVNTNKMRRKIEEQIQYLIRDNPIPDGTILTTGTAIVPGRDKGLKDEDIVEITISNIGTLITPVKKRRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords 2-keto-3-deoxy-D-arabinonate dehydratase
publication title Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
pubmed doi rcsb
source organism Sulfolobus solfataricus
molecule tags Lyase
total genus 79
structure length 291
sequence length 291
ec nomenclature ec 4.2.1.141: 2-dehydro-3-deoxy-D-arabinonate dehydratase.
pdb deposition date 2007-05-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01557 FAA_hydrolase Fumarylacetoacetate (FAA) hydrolase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.330.40 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 2q1aX01
3.90.850.10 Alpha Beta Alpha-Beta Complex Fumarylacetoacetate hydrolase; domain 2 Fumarylacetoacetase-like, C-terminal domain 2q1aX02
5D2KA 1NKQA 1SAWA 2Q1CX 1WZOA 4DBFA 5D2GA 4PFZA 2Q1AX 1QQJA 2Q19X 2EB6A 3V77A 3BQBA 4DBHA 5D2IA 1QCOA 2EB5A 2HZYA 2DFUA 4MAQA 4QKUA 3S52A 5D2JA 1SV6A 1HYOA 3LZKA 2Q1DX 1I7OA 2Q18X 2EB4A 2WQTA 1GTTA 3R6OA 5D2HA 5D2FA 3QDFA 3RR6A 1QCNA 1NR9A
chains in the Genus database with same CATH superfamily
1ZC1A 3FPUA 2Q1CX 1WZOA 2B25A 5D2GA 5DYIA 3QC8A 4UC4A 5FTKA 5EPPA 5FTMA 1S3SA 3LGAA 2EB5A 2YUJA 2HZYA 2DFUA 5EQJB 2QQSA 3ZGZA 2Q18X 3QDFA 3LZKA 3ZJVA 4ARIA 1E32A 4RV0A 4PFZA 5D6XA 3FPTA 3QQ8A 1QQJA 4AQ7A 4DBHA 2PJHB 2MM2A 3HU3A 2XDPA 2MM0A 4FIBA 2KY9A 5GLFA 3ZJUA 5FTJA 1SV6A 4CQNA 5C1BA 2Q1DX 5ERGB 1I7OA 2QQRA 5CCXA 2WQTA 5D6YA 5FTNA 5D6WA 5C18A 3HU2A 3CF2A 5D2HA 3TIWA 1I9GA 1QCNA 3RR6A 2GF7A 5FTLA 1SAWA 2YVLA 4DBFA 2GFAA 2PWYA 2Q1AX 4KDIA 3V77A 1CZ4A 5CCBA 1QCOA 4MAQA 4KLNA 1QCSA 3QWZA 1WLFA 4QKUA 3S52A 5B6CA 5D2JA 1HYOA 1CR5A 4AS1A 5D2FA 1GTTA 3ZJTA 1NR9A 2JV2A 4KODA 3QQ7A 1NKQA 5D2KA 1QDNA 3LHDA 5CD1A 1R7RA 5DYGA 2Q19X 2EB6A 3BQBA 4KDLA 5D2IA 1O54A 3HU1A 4ARCA 4KO8A 3FPRA 3MB5A 2LW6A 2EB4A 1CZ5A 3R6OA
chains in the Genus database with same CATH topology
1ZC1A 3FPUA 2Q1CX 1WZOA 2B25A 5D2GA 5DYIA 3QC8A 4UC4A 5FTKA 5EPPA 5FTMA 1S3SA 3LGAA 2EB5A 2YUJA 2HZYA 2DFUA 5EQJB 2QQSA 3ZGZA 2Q18X 3QDFA 3LZKA 3ZJVA 4ARIA 1E32A 4RV0A 4PFZA 5D6XA 3FPTA 3QQ8A 1QQJA 4AQ7A 4DBHA 2PJHB 2MM2A 3HU3A 2XDPA 2MM0A 4FIBA 2KY9A 5GLFA 3ZJUA 5FTJA 1SV6A 4CQNA 5C1BA 2Q1DX 5ERGB 1I7OA 2QQRA 5CCXA 2WQTA 5D6YA 5FTNA 5D6WA 5C18A 3HU2A 3CF2A 5D2HA 3TIWA 1I9GA 1QCNA 3RR6A 2GF7A 5FTLA 1SAWA 2YVLA 4DBFA 2GFAA 2PWYA 2Q1AX 4KDIA 3V77A 1CZ4A 5CCBA 1QCOA 4MAQA 4KLNA 1QCSA 3QWZA 1WLFA 4QKUA 3S52A 5B6CA 5D2JA 1HYOA 1CR5A 4AS1A 5D2FA 1GTTA 3ZJTA 1NR9A 2JV2A 4KODA 3QQ7A 1NKQA 5D2KA 1QDNA 3LHDA 5CD1A 1R7RA 5DYGA 2Q19X 2EB6A 3BQBA 4KDLA 5D2IA 1O54A 3HU1A 4ARCA 4KO8A 3FPRA 3MB5A 2LW6A 2EB4A 1CZ5A 3R6OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5D2K A;  1NKQ A;  1SAW A;  2Q1C X;  1WZO A;  4DBF A;  5D2G A;  4PFZ A;  2Q1A X;  1QQJ A;  2Q19 X;  2EB6 A;  3V77 A;  3BQB A;  4DBH A;  5D2I A;  1QCO A;  2EB5 A;  2HZY A;  2DFU A;  4MAQ A;  4QKU A;  3S52 A;  5D2J A;  1SV6 A;  1HYO A;  3LZK A;  2Q1D X;  1I7O A;  2Q18 X;  2EB4 A;  2WQT A;  1GTT A;  3R6O A;  5D2H A;  5D2F A;  3QDF A;  3RR6 A;  1QCN A;  1NR9 A; 
#chains in the Genus database with same CATH topology
 1ZC1 A;  3FPU A;  2Q1C X;  1WZO A;  2B25 A;  5D2G A;  5DYI A;  3QC8 A;  4UC4 A;  5FTK A;  5EPP A;  5FTM A;  1S3S A;  3LGA A;  2EB5 A;  2YUJ A;  2HZY A;  2DFU A;  5EQJ B;  2QQS A;  3ZGZ A;  2Q18 X;  3QDF A;  3LZK A;  3ZJV A;  4ARI A;  1E32 A;  4RV0 A;  4PFZ A;  5D6X A;  3FPT A;  3QQ8 A;  1QQJ A;  4AQ7 A;  4DBH A;  2PJH B;  2MM2 A;  3HU3 A;  2XDP A;  2MM0 A;  4FIB A;  2KY9 A;  5GLF A;  3ZJU A;  5FTJ A;  1SV6 A;  4CQN A;  5C1B A;  2Q1D X;  5ERG B;  1I7O A;  2QQR A;  5CCX A;  2WQT A;  5D6Y A;  5FTN A;  5D6W A;  5C18 A;  3HU2 A;  3CF2 A;  5D2H A;  3TIW A;  1I9G A;  1QCN A;  3RR6 A;  2GF7 A;  5FTL A;  1SAW A;  2YVL A;  4DBF A;  2GFA A;  2PWY A;  2Q1A X;  4KDI A;  3V77 A;  1CZ4 A;  5CCB A;  1QCO A;  4MAQ A;  4KLN A;  1QCS A;  3QWZ A;  1WLF A;  4QKU A;  3S52 A;  5B6C A;  5D2J A;  1HYO A;  1CR5 A;  4AS1 A;  5D2F A;  1GTT A;  3ZJT A;  1NR9 A;  2JV2 A;  4KOD A;  3QQ7 A;  1NKQ A;  5D2K A;  1QDN A;  3LHD A;  5CD1 A;  1R7R A;  5DYG A;  2Q19 X;  2EB6 A;  3BQB A;  4KDL A;  5D2I A;  1O54 A;  3HU1 A;  4ARC A;  4KO8 A;  3FPR A;  3MB5 A;  2LW6 A;  2EB4 A;  1CZ5 A;  3R6O A; 
#chains in the Genus database with same CATH homology
 1ZC1 A;  3FPU A;  2Q1C X;  1WZO A;  2B25 A;  5D2G A;  5DYI A;  3QC8 A;  4UC4 A;  5FTK A;  5EPP A;  5FTM A;  1S3S A;  3LGA A;  2EB5 A;  2YUJ A;  2HZY A;  2DFU A;  5EQJ B;  2QQS A;  3ZGZ A;  2Q18 X;  3QDF A;  3LZK A;  3ZJV A;  4ARI A;  1E32 A;  4RV0 A;  4PFZ A;  5D6X A;  3FPT A;  3QQ8 A;  1QQJ A;  4AQ7 A;  4DBH A;  2PJH B;  2MM2 A;  3HU3 A;  2XDP A;  2MM0 A;  4FIB A;  2KY9 A;  5GLF A;  3ZJU A;  5FTJ A;  1SV6 A;  4CQN A;  5C1B A;  2Q1D X;  5ERG B;  1I7O A;  2QQR A;  5CCX A;  2WQT A;  5D6Y A;  5FTN A;  5D6W A;  5C18 A;  3HU2 A;  3CF2 A;  5D2H A;  3TIW A;  1I9G A;  1QCN A;  3RR6 A;  2GF7 A;  5FTL A;  1SAW A;  2YVL A;  4DBF A;  2GFA A;  2PWY A;  2Q1A X;  4KDI A;  3V77 A;  1CZ4 A;  5CCB A;  1QCO A;  4MAQ A;  4KLN A;  1QCS A;  3QWZ A;  1WLF A;  4QKU A;  3S52 A;  5B6C A;  5D2J A;  1HYO A;  1CR5 A;  4AS1 A;  5D2F A;  1GTT A;  3ZJT A;  1NR9 A;  2JV2 A;  4KOD A;  3QQ7 A;  1NKQ A;  5D2K A;  1QDN A;  3LHD A;  5CD1 A;  1R7R A;  5DYG A;  2Q19 X;  2EB6 A;  3BQB A;  4KDL A;  5D2I A;  1O54 A;  3HU1 A;  4ARC A;  4KO8 A;  3FPR A;  3MB5 A;  2LW6 A;  2EB4 A;  1CZ5 A;  3R6O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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