2Q1AX

2-keto-3-deoxy-d-arabinonate dehydratase complexed with magnesium and 2-oxobutyrate
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
291
structure length
291
Chain Sequence
MKLFRVVKRGYYISYAILDNSTIIRLDEDPIKALMRYSENKEVLGDRVTGIDYQSLLKSFQINDIRITKPIDPPEVWGSGISYEMARERYSEENVAKILGKTIYEKVYDAVRPEIFFKATPNRCVGHGEAIAVRSDSEWTLPEPELAVVLDSNGKILGYTIMDDVSARDLEAENPLYLPQSKIYAGCCAFGPVIVTSDEIKNPYSLDITLKIVREGRVFFEGSVNTNKMRRKIEEQIQYLIRDNPIPDGTILTTGTAIVPGRDKGLKDEDIVEITISNIGTLITPVKKRRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
pubmed doi rcsb
source organism Sulfolobus solfataricus
molecule tags Lyase
molecule keywords 2-keto-3-deoxy-D-arabinonate dehydratase
total genus 79
structure length 291
sequence length 291
ec nomenclature ec 4.2.1.141: 2-dehydro-3-deoxy-D-arabinonate dehydratase.
pdb deposition date 2007-05-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01557 FAA_hydrolase Fumarylacetoacetate (FAA) hydrolase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.330.40 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 2q1aX01
3.90.850.10 Alpha Beta Alpha-Beta Complex Fumarylacetoacetate hydrolase; domain 2 Fumarylacetoacetase-like, C-terminal domain 2q1aX02
4QKUA 1WZOA 1QCNA 1NKQA 3RR6A 3S52A 2Q1DX 4MAQA 4DBHA 2Q1AX 5D2HA 2WQTA 5D2GA 5D2KA 2DFUA 1QCOA 1GTTA 2EB5A 5D2JA 2Q1CX 2Q18X 1HYOA 1QQJA 5D2FA 3V77A 3R6OA 1SAWA 3BQBA 2EB6A 4DBFA 3LZKA 5D2IA 2Q19X 2HZYA 3QDFA 2EB4A 1I7OA 4PFZA 1NR9A 1SV6A
chains in the Genus database with same CATH superfamily
4KO8A 2MM0A 4MAQA 1WLFA 2Q1CX 5ERGB 3LHDA 1R7RA 5FTJA 3ZJUA 1CZ5A 4AQ7A 2Q19X 5DYIA 3QDFA 2YUJA 2YVLA 4PFZA 3CF2A 2LW6A 5B6CA 4QKUA 1WZOA 3HU2A 5CD1A 3RR6A 2WQTA 5C1BA 1ZC1A 2B25A 5D6WA 5EPPA 5EQJB 5D2JA 4AS1A 2Q18X 3QQ8A 3V77A 3ZJTA 4KLNA 2PWYA 1SAWA 2EB6A 1S3SA 4DBFA 3LZKA 3HU3A 4KODA 4CQNA 3QC8A 5CCBA 4RV0A 3FPRA 5C18A 3S52A 4DBHA 2Q1AX 5D2GA 5D2KA 3LGAA 5FTNA 3ZJVA 2GF7A 5D6YA 3TIWA 1QCOA 2QQRA 2EB5A 3ZGZA 5FTLA 5D2FA 2XDPA 5FTKA 3R6OA 3BQBA 2KY9A 2JV2A 1I7OA 4UC4A 1NR9A 2QQSA 5D6XA 1QCNA 4KDLA 1CZ4A 5GLFA 1NKQA 2Q1DX 1QCSA 5D2HA 4KDIA 2MM2A 2GFAA 3QQ7A 2DFUA 1GTTA 3FPTA 1CR5A 1HYOA 3FPUA 1QQJA 2PJHB 4ARCA 4ARIA 3QWZA 5FTMA 5CCXA 1O54A 5DYGA 5D2IA 2HZYA 2EB4A 1E32A 1QDNA 3HU1A 1I9GA 3MB5A 4FIBA 1SV6A
chains in the Genus database with same CATH topology
4KO8A 2MM0A 4MAQA 1WLFA 2Q1CX 5ERGB 3LHDA 1R7RA 5FTJA 3ZJUA 1CZ5A 4AQ7A 2Q19X 5DYIA 3QDFA 2YUJA 2YVLA 4PFZA 3CF2A 2LW6A 5B6CA 4QKUA 1WZOA 3HU2A 5CD1A 3RR6A 2WQTA 5C1BA 1ZC1A 2B25A 5D6WA 5EPPA 5EQJB 5D2JA 4AS1A 2Q18X 3QQ8A 3V77A 3ZJTA 4KLNA 2PWYA 1SAWA 2EB6A 1S3SA 4DBFA 3LZKA 3HU3A 4KODA 4CQNA 3QC8A 5CCBA 4RV0A 3FPRA 5C18A 3S52A 4DBHA 2Q1AX 5D2GA 5D2KA 3LGAA 5FTNA 3ZJVA 2GF7A 5D6YA 3TIWA 1QCOA 2QQRA 2EB5A 3ZGZA 5FTLA 5D2FA 2XDPA 5FTKA 3R6OA 3BQBA 2KY9A 2JV2A 1I7OA 4UC4A 1NR9A 2QQSA 5D6XA 1QCNA 4KDLA 1CZ4A 5GLFA 1NKQA 2Q1DX 1QCSA 5D2HA 4KDIA 2MM2A 2GFAA 3QQ7A 2DFUA 1GTTA 3FPTA 1CR5A 1HYOA 3FPUA 1QQJA 2PJHB 4ARCA 4ARIA 3QWZA 5FTMA 5CCXA 1O54A 5DYGA 5D2IA 2HZYA 2EB4A 1E32A 1QDNA 3HU1A 1I9GA 3MB5A 4FIBA 1SV6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QKU A;  1WZO A;  1QCN A;  1NKQ A;  3RR6 A;  3S52 A;  2Q1D X;  4MAQ A;  4DBH A;  2Q1A X;  5D2H A;  2WQT A;  5D2G A;  5D2K A;  2DFU A;  1QCO A;  1GTT A;  2EB5 A;  5D2J A;  2Q1C X;  2Q18 X;  1HYO A;  1QQJ A;  5D2F A;  3V77 A;  3R6O A;  1SAW A;  3BQB A;  2EB6 A;  4DBF A;  3LZK A;  5D2I A;  2Q19 X;  2HZY A;  3QDF A;  2EB4 A;  1I7O A;  4PFZ A;  1NR9 A;  1SV6 A; 
#chains in the Genus database with same CATH topology
 4KO8 A;  2MM0 A;  4MAQ A;  1WLF A;  2Q1C X;  5ERG B;  3LHD A;  1R7R A;  5FTJ A;  3ZJU A;  1CZ5 A;  4AQ7 A;  2Q19 X;  5DYI A;  3QDF A;  2YUJ A;  2YVL A;  4PFZ A;  3CF2 A;  2LW6 A;  5B6C A;  4QKU A;  1WZO A;  3HU2 A;  5CD1 A;  3RR6 A;  2WQT A;  5C1B A;  1ZC1 A;  2B25 A;  5D6W A;  5EPP A;  5EQJ B;  5D2J A;  4AS1 A;  2Q18 X;  3QQ8 A;  3V77 A;  3ZJT A;  4KLN A;  2PWY A;  1SAW A;  2EB6 A;  1S3S A;  4DBF A;  3LZK A;  3HU3 A;  4KOD A;  4CQN A;  3QC8 A;  5CCB A;  4RV0 A;  3FPR A;  5C18 A;  3S52 A;  4DBH A;  2Q1A X;  5D2G A;  5D2K A;  3LGA A;  5FTN A;  3ZJV A;  2GF7 A;  5D6Y A;  3TIW A;  1QCO A;  2QQR A;  2EB5 A;  3ZGZ A;  5FTL A;  5D2F A;  2XDP A;  5FTK A;  3R6O A;  3BQB A;  2KY9 A;  2JV2 A;  1I7O A;  4UC4 A;  1NR9 A;  2QQS A;  5D6X A;  1QCN A;  4KDL A;  1CZ4 A;  5GLF A;  1NKQ A;  2Q1D X;  1QCS A;  5D2H A;  4KDI A;  2MM2 A;  2GFA A;  3QQ7 A;  2DFU A;  1GTT A;  3FPT A;  1CR5 A;  1HYO A;  3FPU A;  1QQJ A;  2PJH B;  4ARC A;  4ARI A;  3QWZ A;  5FTM A;  5CCX A;  1O54 A;  5DYG A;  5D2I A;  2HZY A;  2EB4 A;  1E32 A;  1QDN A;  3HU1 A;  1I9G A;  3MB5 A;  4FIB A;  1SV6 A; 
#chains in the Genus database with same CATH homology
 4KO8 A;  2MM0 A;  4MAQ A;  1WLF A;  2Q1C X;  5ERG B;  3LHD A;  1R7R A;  5FTJ A;  3ZJU A;  1CZ5 A;  4AQ7 A;  2Q19 X;  5DYI A;  3QDF A;  2YUJ A;  2YVL A;  4PFZ A;  3CF2 A;  2LW6 A;  5B6C A;  4QKU A;  1WZO A;  3HU2 A;  5CD1 A;  3RR6 A;  2WQT A;  5C1B A;  1ZC1 A;  2B25 A;  5D6W A;  5EPP A;  5EQJ B;  5D2J A;  4AS1 A;  2Q18 X;  3QQ8 A;  3V77 A;  3ZJT A;  4KLN A;  2PWY A;  1SAW A;  2EB6 A;  1S3S A;  4DBF A;  3LZK A;  3HU3 A;  4KOD A;  4CQN A;  3QC8 A;  5CCB A;  4RV0 A;  3FPR A;  5C18 A;  3S52 A;  4DBH A;  2Q1A X;  5D2G A;  5D2K A;  3LGA A;  5FTN A;  3ZJV A;  2GF7 A;  5D6Y A;  3TIW A;  1QCO A;  2QQR A;  2EB5 A;  3ZGZ A;  5FTL A;  5D2F A;  2XDP A;  5FTK A;  3R6O A;  3BQB A;  2KY9 A;  2JV2 A;  1I7O A;  4UC4 A;  1NR9 A;  2QQS A;  5D6X A;  1QCN A;  4KDL A;  1CZ4 A;  5GLF A;  1NKQ A;  2Q1D X;  1QCS A;  5D2H A;  4KDI A;  2MM2 A;  2GFA A;  3QQ7 A;  2DFU A;  1GTT A;  3FPT A;  1CR5 A;  1HYO A;  3FPU A;  1QQJ A;  2PJH B;  4ARC A;  4ARI A;  3QWZ A;  5FTM A;  5CCX A;  1O54 A;  5DYG A;  5D2I A;  2HZY A;  2EB4 A;  1E32 A;  1QDN A;  3HU1 A;  1I9G A;  3MB5 A;  4FIB A;  1SV6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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