2Q1DX

2-keto-3-deoxy-d-arabinonate dehydratase complexed with magnesium and 2,5-dioxopentanoate
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
291
structure length
281
Chain Sequence
MKLFRVVKRGYYISYAILDNSTIIRLDEDPIKALMRYSENKEVLGDRVTGIDYQSLLKSFQINDIRITKPIDPPEVWGSGISYNVAKILGKTIYEKVYDAVRPEIFFKATPNRCVGHGEAIAVRSDSEWTLPEPELAVVLDSNGKILGYTIMDDVSARDLEAENPLYLPQSKIYAGCCAFGPVIVTSDEIKNPYSLDITLKIVREGRVFFEGSVNTNKMRRKIEEQIQYLIRDNPIPDGTILTTGTAIVPGRDKGLKDEDIVEITISNIGTLITPVKKRRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
pubmed doi rcsb
source organism Sulfolobus solfataricus
molecule tags Lyase
molecule keywords 2-keto-3-deoxy-D-arabinonate dehydratase
total genus 80
structure length 281
sequence length 291
ec nomenclature ec 4.2.1.141: 2-dehydro-3-deoxy-D-arabinonate dehydratase.
pdb deposition date 2007-05-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01557 FAA_hydrolase Fumarylacetoacetate (FAA) hydrolase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.330.40 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 2q1dX01
3.90.850.10 Alpha Beta Alpha-Beta Complex Fumarylacetoacetate hydrolase; domain 2 Fumarylacetoacetase-like, C-terminal domain 2q1dX02
1QQJA 3LZKA 1SAWA 5D2HA 3S52A 4PFZA 5D2KA 2Q18X 5D2FA 1QCOA 2Q19X 3R6OA 5D2JA 2Q1AX 3V77A 2EB4A 5D2GA 2EB6A 5D2IA 1HYOA 2Q1DX 2HZYA 1NKQA 2EB5A 3QDFA 4DBFA 4MAQA 4DBHA 1I7OA 2WQTA 2DFUA 1WZOA 1NR9A 3RR6A 1QCNA 1SV6A 2Q1CX 3BQBA 4QKUA 1GTTA
chains in the Genus database with same CATH superfamily
3LZKA 1QCSA 5D2HA 2YUJA 1WLFA 3MB5A 4AS1A 5D2IA 4KLNA 1R7RA 2HZYA 5C18A 2EB5A 3CF2A 2QQSA 4DBFA 3QC8A 2DFUA 4ARIA 2GF7A 4AQ7A 3TIWA 4FIBA 2MM0A 1GTTA 5EQJB 2YVLA 4KODA 5FTLA 5CD1A 5D2KA 2Q18X 5B6CA 3FPTA 5D2FA 1I9GA 2Q19X 3R6OA 5D2JA 3V77A 2PWYA 2EB4A 2EB6A 3QQ7A 3FPUA 1HYOA 2Q1DX 1CZ4A 4KDIA 4KO8A 5DYIA 3ZJVA 1S3SA 4MAQA 1WZOA 5C1BA 5FTKA 3HU1A 2B25A 5FTMA 3HU2A 2Q1CX 3LHDA 1O54A 2MM2A 3FPRA 3HU3A 4PFZA 2XDPA 5EPPA 1QCOA 5FTNA 2Q1AX 4ARCA 5D2GA 1ZC1A 5GLFA 2QQRA 5D6XA 5ERGB 3ZJTA 1NKQA 1CZ5A 3QDFA 3QWZA 2GFAA 5CCXA 4DBHA 1I7OA 2WQTA 3RR6A 4CQNA 5CCBA 1QCNA 3ZGZA 5D6WA 3BQBA 4UC4A 3QQ8A 3LGAA 1QQJA 1SAWA 1CR5A 1E32A 3S52A 5DYGA 1QDNA 2KY9A 2PJHB 5D6YA 4KDLA 3ZJUA 2LW6A 1NR9A 2JV2A 5FTJA 1SV6A 4RV0A 4QKUA
chains in the Genus database with same CATH topology
3LZKA 1QCSA 5D2HA 2YUJA 1WLFA 3MB5A 4AS1A 5D2IA 4KLNA 1R7RA 2HZYA 5C18A 2EB5A 3CF2A 2QQSA 4DBFA 3QC8A 2DFUA 4ARIA 2GF7A 4AQ7A 3TIWA 4FIBA 2MM0A 1GTTA 5EQJB 2YVLA 4KODA 5FTLA 5CD1A 5D2KA 2Q18X 5B6CA 3FPTA 5D2FA 1I9GA 2Q19X 3R6OA 5D2JA 3V77A 2PWYA 2EB4A 2EB6A 3QQ7A 3FPUA 1HYOA 2Q1DX 1CZ4A 4KDIA 4KO8A 5DYIA 3ZJVA 1S3SA 4MAQA 1WZOA 5C1BA 5FTKA 3HU1A 2B25A 5FTMA 3HU2A 2Q1CX 3LHDA 1O54A 2MM2A 3FPRA 3HU3A 4PFZA 2XDPA 5EPPA 1QCOA 5FTNA 2Q1AX 4ARCA 5D2GA 1ZC1A 5GLFA 2QQRA 5D6XA 5ERGB 3ZJTA 1NKQA 1CZ5A 3QDFA 3QWZA 2GFAA 5CCXA 4DBHA 1I7OA 2WQTA 3RR6A 4CQNA 5CCBA 1QCNA 3ZGZA 5D6WA 3BQBA 4UC4A 3QQ8A 3LGAA 1QQJA 1SAWA 1CR5A 1E32A 3S52A 5DYGA 1QDNA 2KY9A 2PJHB 5D6YA 4KDLA 3ZJUA 2LW6A 1NR9A 2JV2A 5FTJA 1SV6A 4RV0A 4QKUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QQJ A;  3LZK A;  1SAW A;  5D2H A;  3S52 A;  4PFZ A;  5D2K A;  2Q18 X;  5D2F A;  1QCO A;  2Q19 X;  3R6O A;  5D2J A;  2Q1A X;  3V77 A;  2EB4 A;  5D2G A;  2EB6 A;  5D2I A;  1HYO A;  2Q1D X;  2HZY A;  1NKQ A;  2EB5 A;  3QDF A;  4DBF A;  4MAQ A;  4DBH A;  1I7O A;  2WQT A;  2DFU A;  1WZO A;  1NR9 A;  3RR6 A;  1QCN A;  1SV6 A;  2Q1C X;  3BQB A;  4QKU A;  1GTT A; 
#chains in the Genus database with same CATH topology
 3LZK A;  1QCS A;  5D2H A;  2YUJ A;  1WLF A;  3MB5 A;  4AS1 A;  5D2I A;  4KLN A;  1R7R A;  2HZY A;  5C18 A;  2EB5 A;  3CF2 A;  2QQS A;  4DBF A;  3QC8 A;  2DFU A;  4ARI A;  2GF7 A;  4AQ7 A;  3TIW A;  4FIB A;  2MM0 A;  1GTT A;  5EQJ B;  2YVL A;  4KOD A;  5FTL A;  5CD1 A;  5D2K A;  2Q18 X;  5B6C A;  3FPT A;  5D2F A;  1I9G A;  2Q19 X;  3R6O A;  5D2J A;  3V77 A;  2PWY A;  2EB4 A;  2EB6 A;  3QQ7 A;  3FPU A;  1HYO A;  2Q1D X;  1CZ4 A;  4KDI A;  4KO8 A;  5DYI A;  3ZJV A;  1S3S A;  4MAQ A;  1WZO A;  5C1B A;  5FTK A;  3HU1 A;  2B25 A;  5FTM A;  3HU2 A;  2Q1C X;  3LHD A;  1O54 A;  2MM2 A;  3FPR A;  3HU3 A;  4PFZ A;  2XDP A;  5EPP A;  1QCO A;  5FTN A;  2Q1A X;  4ARC A;  5D2G A;  1ZC1 A;  5GLF A;  2QQR A;  5D6X A;  5ERG B;  3ZJT A;  1NKQ A;  1CZ5 A;  3QDF A;  3QWZ A;  2GFA A;  5CCX A;  4DBH A;  1I7O A;  2WQT A;  3RR6 A;  4CQN A;  5CCB A;  1QCN A;  3ZGZ A;  5D6W A;  3BQB A;  4UC4 A;  3QQ8 A;  3LGA A;  1QQJ A;  1SAW A;  1CR5 A;  1E32 A;  3S52 A;  5DYG A;  1QDN A;  2KY9 A;  2PJH B;  5D6Y A;  4KDL A;  3ZJU A;  2LW6 A;  1NR9 A;  2JV2 A;  5FTJ A;  1SV6 A;  4RV0 A;  4QKU A; 
#chains in the Genus database with same CATH homology
 3LZK A;  1QCS A;  5D2H A;  2YUJ A;  1WLF A;  3MB5 A;  4AS1 A;  5D2I A;  4KLN A;  1R7R A;  2HZY A;  5C18 A;  2EB5 A;  3CF2 A;  2QQS A;  4DBF A;  3QC8 A;  2DFU A;  4ARI A;  2GF7 A;  4AQ7 A;  3TIW A;  4FIB A;  2MM0 A;  1GTT A;  5EQJ B;  2YVL A;  4KOD A;  5FTL A;  5CD1 A;  5D2K A;  2Q18 X;  5B6C A;  3FPT A;  5D2F A;  1I9G A;  2Q19 X;  3R6O A;  5D2J A;  3V77 A;  2PWY A;  2EB4 A;  2EB6 A;  3QQ7 A;  3FPU A;  1HYO A;  2Q1D X;  1CZ4 A;  4KDI A;  4KO8 A;  5DYI A;  3ZJV A;  1S3S A;  4MAQ A;  1WZO A;  5C1B A;  5FTK A;  3HU1 A;  2B25 A;  5FTM A;  3HU2 A;  2Q1C X;  3LHD A;  1O54 A;  2MM2 A;  3FPR A;  3HU3 A;  4PFZ A;  2XDP A;  5EPP A;  1QCO A;  5FTN A;  2Q1A X;  4ARC A;  5D2G A;  1ZC1 A;  5GLF A;  2QQR A;  5D6X A;  5ERG B;  3ZJT A;  1NKQ A;  1CZ5 A;  3QDF A;  3QWZ A;  2GFA A;  5CCX A;  4DBH A;  1I7O A;  2WQT A;  3RR6 A;  4CQN A;  5CCB A;  1QCN A;  3ZGZ A;  5D6W A;  3BQB A;  4UC4 A;  3QQ8 A;  3LGA A;  1QQJ A;  1SAW A;  1CR5 A;  1E32 A;  3S52 A;  5DYG A;  1QDN A;  2KY9 A;  2PJH B;  5D6Y A;  4KDL A;  3ZJU A;  2LW6 A;  1NR9 A;  2JV2 A;  5FTJ A;  1SV6 A;  4RV0 A;  4QKU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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