2QBQA

Crystal structure of ptp1b-inhibitor complex
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-based optimization of protein tyrosine phosphatase 1B inhibitors: from the active site to the second phosphotyrosine binding site.
pubmed doi rcsb
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
molecule tags Hydrolase
source organism Homo sapiens
total genus 102
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2007-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2qbqA00
1XM2A 4D3RA 2I4HA 2H04A 2I6PA 1VHRA 5IBSA 2A8BA 2PSZA 2NTAA 1C83A 1YN9A 1G1HA 1I9TA 1PXHA 3V0JA 2MBCA 1QXKA 3RGOA 5I6VA 1T4JA 4JNBA 3ZM3A 4OHDA 1YGRA 2PA5A 2F71A 1PA9A 4QAHA 4D3QA 1I9SA 1MKPA 2Y96A 2I1YA 5KA4A 5K9VA 1G7FA 4ZI4A 5KABA 4AZ1A 1XXVA 3O3LA 3MMJA 1AAXA 3RZ2A 3QCHA 4RDDA 4S0GA 2B4PA 1GFYA 4NWFA 2VEXA 3S3KA 4MBBA 4DGXA 5BZZA 2HCMA 2F6VA 2QDCA 3ZMPA 4NWGA 2YDUA 5K22A 4BPCA 2NZ6A 2F70A 2QBPA 2QEPA 2QBRA 1YTSA 5K24A 5M43A 1U26A 3EMUA 2VEUA 4HRFA 3EU0A 2J17A 1OEUA 4TVVA 1XRIA 4WOHA 4RHGA 4QBWA 2CM2A 1A5YA 3QCKA 1Q6SA 2HB1A 4RKKA 5KA3A 2I4GA 2CMAA 1YTNA 1YPTA 2I6JA 1YWFA 1XBOA 1OHDA 5KACA 1Q1MA 2HVLA 4GE5A 2B4OA 1ZCLA 2WGPA 2SHPA 2NT2A 1M3GA 5MMZB 2H03A 5EHPA 5BZXA 4NX8A 1G1FA 1NZ7A 2R0BA 5KA9A 2CNGA 3QCDA 4HJPA 1SUGA 1G4WR 4GE6A 1YGUA 4IKCA 1PH0A 2CMBA 3BRHA 2H4KA 2P4DA 2E0TA 3EB1A 4GRZA 3ZV2A 4H1OA 1Q6MA 4I8NA 2Q47A 1LQFA 2CFVA 2IMGA 1OEVA 1OHEA 2BV5A 3EAXA 3O4SA 2GP0A 3A5JA 3QCBA 5IBMA 2ESBA 2P6XA 3U96A 1Q6TA 2I3RA 3S4OA 5KA8A 1J4XA 3QKPA 4RH5A 4NYHA 4JBCA 4B04A 1RXDA 1PTYA 2FH7A 2HNPA 3BLUA 3SR9A 2J16B 3QCGA 1BZHA 3I36A 4R30A 4RI5A 4WU2A 1PTUA 4GE2A 2H02A 2B4SA 4R0SA 1U25A 3AWFA 2QBQA 4OHEA 3MOZA 2F6WA 3RO1A 2FJMA 1C88A 3EZZA 4Z6BA 2F6TA 1ONZA 1YZ4A 2CM3A 1WCHA 1EEOA 2CM8A 5BX1A 5HDEA 2HXPA 4WU3A 3I7ZA 2I42A 3B7OA 4QBEA 1QZ0A 2HC2A 3V0HA 2VEVA 3F41A 1OEOX 2B07A 1NWEA 1NWLA 2OOQA 4JMKA 5K23A 2GWOA 2NV5A 3V0GA 2BIJA 1G7GA 2I4EA 3QKQA 3V0FA 3S3EA 1C86A 4PYHA 3M4UA 4OHHA 1YFOA 1C84A 1U24A 1XXPA 2I6OA 2PBNA 5EHRA 4QUMA 5J8RA 1T49A 4KYRA 4RH9A 1PTVA 2RF6A 3GXGA 5KA0A 3NMEA 1OETA 2M3VA 2CM7A 1JLNA 2QCTA 3QCIA 2Y2FA 2FJNA 2OUDA 1EENA 4ERCA 2ZN7A 3ZMQA 2F6ZA 2VEWA 3PS5A 5GTJA 2QCJA 3ZM1A 2B49A 4NNDA 4RI4A 4WTYA 3F81A 5KA7A 2JJDA 4YR8B 1GWZA 3AWGA 2C7SA 1Q6JA 2QBSA 3BLTA 1JF7A 4R0TA 4ZRTA 5BUGA 3ZM2A 2PT0A 3AWEA 1C85A 1BZCA 3QCCA 3F9AA 3V0IA 2AHSA 3D42A 2VEYA 4PVGA 2B3OA 1WAXA 3D9CA 2PI7A 2BGDA 2OZ5A 2CNEA 2CNHA 4Y2EA 5LXQB 4GFVA 1OEMX 2ZMMA 1P15A 3OMHA 3GXHA 3OLRA 4GS0A 4HJQA 2PQ5A 3V0DA 1ZZWA 2H4VA 1NNYA 3SMEA 2NLKA 3A5KA 3O5XA 2CNFA 2I6MA 3O4UA 4GWFA 3D1QA 4BJOA 1OESA 2HY3A 4OHLA 4QAPA 3I80A 5KAAA 4J51A 3QCLA 1BZJA 1V3AA 2NT7A 1ZCKA 1C87A 1Q6NA 3S4EA 2Q05A 3ZM0A 2AZRA 4KYQA 3F9BA 4GRYA 4GFUA 2C46A 1PA1A 1ZC0A 3QCEA 1WRMA 4KI9A 4YAAA 4QUNA 1G4US 2I3UA 2CMCA 4ZN5A 3V0EA 2DXPA 1OHCA 1ECVA 5KA2A 1YTWA 1FQ1A 2F6FA 3O4TA 2HNQA 1Q6PA 2H4GA 3QCFA 2I6IA 4D3PA 5K25A 2QDMA 1PYNA 1L8GA 2I75A 2CNIA 1X24A 3F99A 2A3KA 2F6YA 1FPRA 2F46A 4Y14A 4DGPA 3MOWA 2J16A 3D1OA 2BGEA 3D1HA 3LJ8A 3H2XA 1D5RA 2I5XA 3D44A 1NL9A 3QCNA 1FPZA 2G59A 1RPMA 2CJZA 3CM3A 4OHIA 2HC1A 1R6HA 3QCMA 1T48A 2G6ZA 1LARA 3N0AA 2BZLA 5K9WA 2OC3A 1ONYA 1I57A 1LYVA 1G1GA 4ICZA 4H34A 1KAVA 5KADA 1L8KA 3RGQA 3S3HA 1KAKA 4JMJA 2B4UA 5KA1A 1NO6A 2GJTA 3CWEA 1PTTA 3QCJA 5AWXA 3S3FA 2QDPA 3BM8A
chains in the Genus database with same CATH superfamily
2JFFA 1XM2A 4D3RA 2I4HA 2H04A 2I6PA 1VHRA 5IBSA 2A8BA 2PSZA 2NTAA 1C83A 1YN9A 1G1HA 1I9TA 1PXHA 2X5OA 3V0JA 2MBCA 1QXKA 3RGOA 5I6VA 1EEHA 1T4JA 1FGSA 4BUCA 2Y67A 4JNBA 3ZM3A 4OHDA 1YGRA 2PA5A 2F71A 1PA9A 4QAHA 3NRSA 4D3QA 1I9SA 1MKPA 2Y96A 2I1YA 5KA4A 5K9VA 1G7FA 4ZI4A 5KABA 4AZ1A 1XXVA 3O3LA 3MMJA 1AAXA 3RZ2A 3QCHA 4RDDA 4ZIYA 4S0GA 2B4PA 1GFYA 4NWFA 2VEXA 3S3KA 4MBBA 4DGXA 5BZZA 2HCMA 2F6VA 2QDCA 3ZMPA 4NWGA 2YDUA 5K22A 4BPCA 2NZ6A 2F70A 2QBPA 2QEPA 4QDIA 2QBRA 1YTSA 5K24A 3UAGA 5M43A 1U26A 3EMUA 2VEUA 4HRFA 3EU0A 2J17A 1OEUA 4TVVA 1XRIA 4WOHA 2XJAA 4RHGA 4CVKA 4QBWA 2CM2A 1A5YA 3QCKA 2Y68A 1Q6SA 2HB1A 4RKKA 5KA3A 2I4GA 2CMAA 1YTNA 1YPTA 2I6JA 4C12A 1YWFA 1XBOA 1OHDA 5KACA 1Q1MA 2HVLA 4GE5A 2B4OA 1ZCLA 2WGPA 2SHPA 2NT2A 1M3GA 2VOSA 2H03A 5MMZB 2Y1OA 5EHPA 5BZXA 4NX8A 1G1FA 1NZ7A 2R0BA 5KA9A 2CNGA 3HN7A 3QCDA 4HJPA 1SUGA 1G4WR 4GE6A 4BUBA 1YGUA 4IKCA 1PH0A 2CMBA 3BRHA 2H4KA 2P4DA 2E0TA 3EB1A 4GRZA 5A5FA 3ZV2A 4H1OA 1Q6MA 4I8NA 2Q47A 1LQFA 4QF5A 2CFVA 2UUOA 2IMGA 1OEVA 1OHEA 2GC5A 1J6UA 2BV5A 3EAXA 3O4SA 2GP0A 3A5JA 3QCBA 5IBMA 2ESBA 2P6XA 3U96A 1Q6TA 2I3RA 3S4OA 5KA8A 4CVLA 1J4XA 3QKPA 4RH5A 4NYHA 4JBCA 4B04A 1RXDA 1PTYA 2FH7A 2HNPA 3BLUA 3SR9A 2GCAA 2J16B 3QCGA 1BZHA 3I36A 4R30A 4RI5A 4WU2A 1UAGA 3ZM6A 1PTUA 4GE2A 2H02A 2B4SA 4R0SA 1U25A 3AWFA 2QBQA 4OHEA 1GQQA 3MOZA 1JBWA 2F6WA 3RO1A 2FJMA 1C88A 3EZZA 4Z6BA 1W7KA 2F6TA 2WJPA 1ONZA 1YZ4A 2XPCA 2CM3A 1WCHA 1EEOA 2CM8A 4UAGA 5BX1A 5HDEA 2HXPA 2VORA 4WU3A 2AM2A 3I7ZA 2I42A 3B7OA 4QBEA 1QZ0A 2HC2A 3V0HA 2VEVA 3F41A 1OEOX 2B07A 1NWEA 1NWLA 2JFGA 2OOQA 4JMKA 5K23A 2GWOA 2NV5A 3V0GA 2BIJA 1G7GA 2JFHA 2I4EA 3QKQA 3V0FA 3S3EA 1C86A 2F00A 4PYHA 3M4UA 4OHHA 1YFOA 1C84A 1U24A 1XXPA 2I6OA 3MVNA 1E0DA 2PBNA 2VTDA 4QUMA 5EHRA 5J8RA 1T49A 4KYRA 2UUPA 4RH9A 1PTVA 2RF6A 3GXGA 5KA0A 3NMEA 1OETA 2M3VA 2CM7A 1JLNA 2QCTA 3QCIA 2Y2FA 2FJNA 2OUDA 1EENA 4ERCA 2ZN7A 3ZMQA 1W78A 2F6ZA 2VEWA 2GC6A 3PS5A 5GTJA 2QCJA 3ZM1A 2B49A 4NNDA 4RI4A 4WTYA 3F81A 5KA7A 2JJDA 4YR8B 1GWZA 3AWGA 2C7SA 1Q6JA 2QBSA 3BLTA 1JF7A 4R0TA 4ZRTA 5BUGA 3ZM2A 2PT0A 3AWEA 5A5EA 1C85A 1BZCA 3QCCA 3F9AA 3V0IA 2AHSA 3D42A 2VEYA 4PVGA 2B3OA 1WAXA 3D9CA 2PI7A 2BGDA 2OZ5A 2CNEA 2CNHA 4Y2EA 5LXQB 4GFVA 1OEMX 2ZMMA 1P15A 3OMHA 3GXHA 3ZL8A 3OLRA 4GS0A 4HJQA 2GCBA 2PQ5A 3V0DA 1ZZWA 2H4VA 1NNYA 3SMEA 2NLKA 4CVMA 3A5KA 3O5XA 3ZM5A 2CNFA 2I6MA 3O4UA 1P3DA 4GWFA 2VTEA 3D1QA 4BJOA 1OESA 2HY3A 4OHLA 4QAPA 3I80A 5KAAA 4J51A 3QCLA 1BZJA 1V3AA 4HV4A 2NT7A 1ZCKA 1C87A 1Q6NA 3S4EA 2Q05A 3ZM0A 2AZRA 4KYQA 1O5ZA 3F9BA 4GRYA 4GFUA 2C46A 1PA1A 1GQYA 1ZC0A 3QCEA 1WRMA 1P31A 4KI9A 4YAAA 4QUNA 1G4US 2I3UA 2CMCA 4ZN5A 3V0EA 2DXPA 1OHCA 1ECVA 5KA2A 1YTWA 1FQ1A 2F6FA 3LK7A 3O4TA 2HNQA 3N2AA 1Q6PA 2H4GA 3QCZA 3QCFA 2I6IA 4D3PA 5K25A 2QDMA 1PYNA 1L8GA 2I75A 2CNIA 1X24A 3F99A 2A3KA 2F6YA 1FPRA 2F46A 4Y14A 2UAGA 4DGPA 2WTZA 3MOWA 2J16A 3D1OA 2BGEA 3D1HA 1E8CA 3LJ8A 3H2XA 1D5RA 2I5XA 2Y66A 3D44A 1NL9A 1GG4A 3QCNA 1FPZA 2G59A 1RPMA 2CJZA 3CM3A 4OHIA 2HC1A 1R6HA 3QCMA 1T48A 2G6ZA 1LARA 3N0AA 2AM1A 2BZLA 5K9WA 2OC3A 1ONYA 1I57A 1LYVA 4C13A 1G1GA 4ICZA 4H34A 1KAVA 5KADA 1JBVA 1L8KA 3RGQA 3PYZA 3S3HA 1KAKA 4JMJA 2B4UA 5KA1A 1NO6A 2GJTA 3CWEA 1PTTA 3QCJA 5AWXA 3S3FA 2QDPA 3BM8A
chains in the Genus database with same CATH topology
1XM2A 4D3RA 2I4HA 2H04A 2I6PA 1VHRA 5IBSA 2A8BA 2PSZA 2NTAA 1C83A 1YN9A 1G1HA 1I9TA 1PXHA 3V0JA 2MBCA 1QXKA 3RGOA 5I6VA 1T4JA 4JNBA 3ZM3A 4OHDA 1YGRA 2PA5A 2F71A 1PA9A 4QAHA 4D3QA 1I9SA 1MKPA 2Y96A 2I1YA 5KA4A 5K9VA 1G7FA 4ZI4A 5KABA 4AZ1A 1XXVA 3O3LA 3MMJA 1AAXA 3RZ2A 3QCHA 4RDDA 4S0GA 2B4PA 1GFYA 4NWFA 2VEXA 3S3KA 4MBBA 4DGXA 5BZZA 2HCMA 2F6VA 2QDCA 3ZMPA 4NWGA 2YDUA 5K22A 4BPCA 2NZ6A 2F70A 2QBPA 2QEPA 2QBRA 1YTSA 5K24A 5M43A 1U26A 3EMUA 2VEUA 4HRFA 3EU0A 2J17A 1OEUA 4TVVA 1XRIA 4WOHA 4RHGA 4QBWA 2CM2A 1A5YA 3QCKA 1Q6SA 2HB1A 4RKKA 5KA3A 2I4GA 2CMAA 1YTNA 1YPTA 2I6JA 1YWFA 1XBOA 1OHDA 5KACA 1Q1MA 2HVLA 4GE5A 2B4OA 1ZCLA 2WGPA 2SHPA 2NT2A 1M3GA 5MMZB 2H03A 5EHPA 5BZXA 4NX8A 1G1FA 1NZ7A 2R0BA 5KA9A 2CNGA 3QCDA 4HJPA 1SUGA 1G4WR 4GE6A 1YGUA 4IKCA 1PH0A 2CMBA 3BRHA 2H4KA 2P4DA 2E0TA 3EB1A 4GRZA 3ZV2A 4H1OA 1Q6MA 4I8NA 2Q47A 1LQFA 2CFVA 2IMGA 1OEVA 1OHEA 2BV5A 3EAXA 3O4SA 2GP0A 3A5JA 3QCBA 5IBMA 2ESBA 2P6XA 3U96A 1Q6TA 2I3RA 3S4OA 5KA8A 1J4XA 3QKPA 4RH5A 4NYHA 4JBCA 4B04A 1RXDA 1PTYA 2FH7A 2HNPA 3BLUA 3SR9A 2J16B 3QCGA 1BZHA 3I36A 4R30A 4RI5A 4WU2A 1PTUA 4GE2A 2H02A 2B4SA 4R0SA 1U25A 3AWFA 2QBQA 4OHEA 3MOZA 2F6WA 3RO1A 2FJMA 1C88A 3EZZA 4Z6BA 2F6TA 1ONZA 1YZ4A 2CM3A 1WCHA 1EEOA 2CM8A 5BX1A 5HDEA 2HXPA 4WU3A 3I7ZA 2I42A 3B7OA 4QBEA 1QZ0A 2HC2A 3V0HA 2VEVA 3F41A 1OEOX 2B07A 1NWEA 1NWLA 2OOQA 4JMKA 5K23A 2GWOA 2NV5A 3V0GA 2BIJA 1G7GA 2I4EA 3QKQA 3V0FA 3S3EA 1C86A 4PYHA 3M4UA 4OHHA 1YFOA 1C84A 1U24A 1XXPA 2I6OA 2PBNA 5EHRA 4QUMA 5J8RA 1T49A 4KYRA 4RH9A 1PTVA 2RF6A 3GXGA 5KA0A 3NMEA 1OETA 2M3VA 2CM7A 1JLNA 2QCTA 3QCIA 2Y2FA 2FJNA 2OUDA 1EENA 4ERCA 2ZN7A 3ZMQA 2F6ZA 2VEWA 3PS5A 5GTJA 2QCJA 3ZM1A 2B49A 4NNDA 4RI4A 4WTYA 3F81A 5KA7A 2JJDA 4YR8B 1GWZA 3AWGA 2C7SA 1Q6JA 2QBSA 3BLTA 1JF7A 4R0TA 4ZRTA 5BUGA 3ZM2A 2PT0A 3AWEA 1C85A 1BZCA 3QCCA 3F9AA 3V0IA 2AHSA 3D42A 2VEYA 4PVGA 2B3OA 1WAXA 3D9CA 2PI7A 2BGDA 2OZ5A 2CNEA 2CNHA 4Y2EA 5LXQB 4GFVA 1OEMX 2ZMMA 1P15A 3OMHA 3GXHA 3OLRA 4GS0A 4HJQA 2PQ5A 3V0DA 1ZZWA 2H4VA 1NNYA 3SMEA 2NLKA 3A5KA 3O5XA 2CNFA 2I6MA 3O4UA 4GWFA 3D1QA 4BJOA 1OESA 2HY3A 4OHLA 4QAPA 3I80A 5KAAA 4J51A 3QCLA 1BZJA 1V3AA 2NT7A 1ZCKA 1C87A 1Q6NA 3S4EA 2Q05A 3ZM0A 2AZRA 4KYQA 3F9BA 4GRYA 4GFUA 2C46A 1PA1A 1ZC0A 3QCEA 1WRMA 4KI9A 4YAAA 4QUNA 1G4US 2I3UA 2CMCA 4ZN5A 3V0EA 2DXPA 1OHCA 1ECVA 5KA2A 1YTWA 1FQ1A 2F6FA 3O4TA 2HNQA 1Q6PA 2H4GA 3QCFA 2I6IA 4D3PA 5K25A 2QDMA 1PYNA 1L8GA 2I75A 2CNIA 1X24A 3F99A 2A3KA 2F6YA 1FPRA 2F46A 4Y14A 4DGPA 3MOWA 2J16A 3D1OA 2BGEA 3D1HA 3LJ8A 3H2XA 1D5RA 2I5XA 3D44A 1NL9A 3QCNA 1FPZA 2G59A 1RPMA 2CJZA 3CM3A 4OHIA 2HC1A 1R6HA 3QCMA 1T48A 2G6ZA 1LARA 3N0AA 2BZLA 5K9WA 2OC3A 1ONYA 1I57A 1LYVA 1G1GA 4ICZA 4H34A 1KAVA 5KADA 1L8KA 3RGQA 3S3HA 1KAKA 4JMJA 2B4UA 5KA1A 1NO6A 2GJTA 3CWEA 1PTTA 3QCJA 5AWXA 3S3FA 2QDPA 3BM8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XM2 A;  4D3R A;  2I4H A;  2H04 A;  2I6P A;  1VHR A;  5IBS A;  2A8B A;  2PSZ A;  2NTA A;  1C83 A;  1YN9 A;  1G1H A;  1I9T A;  1PXH A;  3V0J A;  2MBC A;  1QXK A;  3RGO A;  5I6V A;  1T4J A;  4JNB A;  3ZM3 A;  4OHD A;  1YGR A;  2PA5 A;  2F71 A;  1PA9 A;  4QAH A;  4D3Q A;  1I9S A;  1MKP A;  2Y96 A;  2I1Y A;  5KA4 A;  5K9V A;  1G7F A;  4ZI4 A;  5KAB A;  4AZ1 A;  1XXV A;  3O3L A;  3MMJ A;  1AAX A;  3RZ2 A;  3QCH A;  4RDD A;  4S0G A;  2B4P A;  1GFY A;  4NWF A;  2VEX A;  3S3K A;  4MBB A;  4DGX A;  5BZZ A;  2HCM A;  2F6V A;  2QDC A;  3ZMP A;  4NWG A;  2YDU A;  5K22 A;  4BPC A;  2NZ6 A;  2F70 A;  2QBP A;  2QEP A;  2QBR A;  1YTS A;  5K24 A;  5M43 A;  1U26 A;  3EMU A;  2VEU A;  4HRF A;  3EU0 A;  2J17 A;  1OEU A;  4TVV A;  1XRI A;  4WOH A;  4RHG A;  4QBW A;  2CM2 A;  1A5Y A;  3QCK A;  1Q6S A;  2HB1 A;  4RKK A;  5KA3 A;  2I4G A;  2CMA A;  1YTN A;  1YPT A;  2I6J A;  1YWF A;  1XBO A;  1OHD A;  5KAC A;  1Q1M A;  2HVL A;  4GE5 A;  2B4O A;  1ZCL A;  2WGP A;  2SHP A;  2NT2 A;  1M3G A;  5MMZ B;  2H03 A;  5EHP A;  5BZX A;  4NX8 A;  1G1F A;  1NZ7 A;  2R0B A;  5KA9 A;  2CNG A;  3QCD A;  4HJP A;  1SUG A;  1G4W R;  4GE6 A;  1YGU A;  4IKC A;  1PH0 A;  2CMB A;  3BRH A;  2H4K A;  2P4D A;  2E0T A;  3EB1 A;  4GRZ A;  3ZV2 A;  4H1O A;  1Q6M A;  4I8N A;  2Q47 A;  1LQF A;  2CFV A;  2IMG A;  1OEV A;  1OHE A;  2BV5 A;  3EAX A;  3O4S A;  2GP0 A;  3A5J A;  3QCB A;  5IBM A;  2ESB A;  2P6X A;  3U96 A;  1Q6T A;  2I3R A;  3S4O A;  5KA8 A;  1J4X A;  3QKP A;  4RH5 A;  4NYH A;  4JBC A;  4B04 A;  1RXD A;  1PTY A;  2FH7 A;  2HNP A;  3BLU A;  3SR9 A;  2J16 B;  3QCG A;  1BZH A;  3I36 A;  4R30 A;  4RI5 A;  4WU2 A;  1PTU A;  4GE2 A;  2H02 A;  2B4S A;  4R0S A;  1U25 A;  3AWF A;  2QBQ A;  4OHE A;  3MOZ A;  2F6W A;  3RO1 A;  2FJM A;  1C88 A;  3EZZ A;  4Z6B A;  2F6T A;  1ONZ A;  1YZ4 A;  2CM3 A;  1WCH A;  1EEO A;  2CM8 A;  5BX1 A;  5HDE A;  2HXP A;  4WU3 A;  3I7Z A;  2I42 A;  3B7O A;  4QBE A;  1QZ0 A;  2HC2 A;  3V0H A;  2VEV A;  3F41 A;  1OEO X;  2B07 A;  1NWE A;  1NWL A;  2OOQ A;  4JMK A;  5K23 A;  2GWO A;  2NV5 A;  3V0G A;  2BIJ A;  1G7G A;  2I4E A;  3QKQ A;  3V0F A;  3S3E A;  1C86 A;  4PYH A;  3M4U A;  4OHH A;  1YFO A;  1C84 A;  1U24 A;  1XXP A;  2I6O A;  2PBN A;  5EHR A;  4QUM A;  5J8R A;  1T49 A;  4KYR A;  4RH9 A;  1PTV A;  2RF6 A;  3GXG A;  5KA0 A;  3NME A;  1OET A;  2M3V A;  2CM7 A;  1JLN A;  2QCT A;  3QCI A;  2Y2F A;  2FJN A;  2OUD A;  1EEN A;  4ERC A;  2ZN7 A;  3ZMQ A;  2F6Z A;  2VEW A;  3PS5 A;  5GTJ A;  2QCJ A;  3ZM1 A;  2B49 A;  4NND A;  4RI4 A;  4WTY A;  3F81 A;  5KA7 A;  2JJD A;  4YR8 B;  1GWZ A;  3AWG A;  2C7S A;  1Q6J A;  2QBS A;  3BLT A;  1JF7 A;  4R0T A;  4ZRT A;  5BUG A;  3ZM2 A;  2PT0 A;  3AWE A;  1C85 A;  1BZC A;  3QCC A;  3F9A A;  3V0I A;  2AHS A;  3D42 A;  2VEY A;  4PVG A;  2B3O A;  1WAX A;  3D9C A;  2PI7 A;  2BGD A;  2OZ5 A;  2CNE A;  2CNH A;  4Y2E A;  5LXQ B;  4GFV A;  1OEM X;  2ZMM A;  1P15 A;  3OMH A;  3GXH A;  3OLR A;  4GS0 A;  4HJQ A;  2PQ5 A;  3V0D A;  1ZZW A;  2H4V A;  1NNY A;  3SME A;  2NLK A;  3A5K A;  3O5X A;  2CNF A;  2I6M A;  3O4U A;  4GWF A;  3D1Q A;  4BJO A;  1OES A;  2HY3 A;  4OHL A;  4QAP A;  3I80 A;  5KAA A;  4J51 A;  3QCL A;  1BZJ A;  1V3A A;  2NT7 A;  1ZCK A;  1C87 A;  1Q6N A;  3S4E A;  2Q05 A;  3ZM0 A;  2AZR A;  4KYQ A;  3F9B A;  4GRY A;  4GFU A;  2C46 A;  1PA1 A;  1ZC0 A;  3QCE A;  1WRM A;  4KI9 A;  4YAA A;  4QUN A;  1G4U S;  2I3U A;  2CMC A;  4ZN5 A;  3V0E A;  2DXP A;  1OHC A;  1ECV A;  5KA2 A;  1YTW A;  1FQ1 A;  2F6F A;  3O4T A;  2HNQ A;  1Q6P A;  2H4G A;  3QCF A;  2I6I A;  4D3P A;  5K25 A;  2QDM A;  1PYN A;  1L8G A;  2I75 A;  2CNI A;  1X24 A;  3F99 A;  2A3K A;  2F6Y A;  1FPR A;  2F46 A;  4Y14 A;  4DGP A;  3MOW A;  2J16 A;  3D1O A;  2BGE A;  3D1H A;  3LJ8 A;  3H2X A;  1D5R A;  2I5X A;  3D44 A;  1NL9 A;  3QCN A;  1FPZ A;  2G59 A;  1RPM A;  2CJZ A;  3CM3 A;  4OHI A;  2HC1 A;  1R6H A;  3QCM A;  1T48 A;  2G6Z A;  1LAR A;  3N0A A;  2BZL A;  5K9W A;  2OC3 A;  1ONY A;  1I57 A;  1LYV A;  1G1G A;  4ICZ A;  4H34 A;  1KAV A;  5KAD A;  1L8K A;  3RGQ A;  3S3H A;  1KAK A;  4JMJ A;  2B4U A;  5KA1 A;  1NO6 A;  2GJT A;  3CWE A;  1PTT A;  3QCJ A;  5AWX A;  3S3F A;  2QDP A;  3BM8 A; 
#chains in the Genus database with same CATH topology
 2JFF A;  1XM2 A;  4D3R A;  2I4H A;  2H04 A;  2I6P A;  1VHR A;  5IBS A;  2A8B A;  2PSZ A;  2NTA A;  1C83 A;  1YN9 A;  1G1H A;  1I9T A;  1PXH A;  2X5O A;  3V0J A;  2MBC A;  1QXK A;  3RGO A;  5I6V A;  1EEH A;  1T4J A;  1FGS A;  4BUC A;  2Y67 A;  4JNB A;  3ZM3 A;  4OHD A;  1YGR A;  2PA5 A;  2F71 A;  1PA9 A;  4QAH A;  3NRS A;  4D3Q A;  1I9S A;  1MKP A;  2Y96 A;  2I1Y A;  5KA4 A;  5K9V A;  1G7F A;  4ZI4 A;  5KAB A;  4AZ1 A;  1XXV A;  3O3L A;  3MMJ A;  1AAX A;  3RZ2 A;  3QCH A;  4RDD A;  4ZIY A;  4S0G A;  2B4P A;  1GFY A;  4NWF A;  2VEX A;  3S3K A;  4MBB A;  4DGX A;  5BZZ A;  2HCM A;  2F6V A;  2QDC A;  3ZMP A;  4NWG A;  2YDU A;  5K22 A;  4BPC A;  2NZ6 A;  2F70 A;  2QBP A;  2QEP A;  4QDI A;  2QBR A;  1YTS A;  5K24 A;  3UAG A;  5M43 A;  1U26 A;  3EMU A;  2VEU A;  4HRF A;  3EU0 A;  2J17 A;  1OEU A;  4TVV A;  1XRI A;  4WOH A;  2XJA A;  4RHG A;  4CVK A;  4QBW A;  2CM2 A;  1A5Y A;  3QCK A;  2Y68 A;  1Q6S A;  2HB1 A;  4RKK A;  5KA3 A;  2I4G A;  2CMA A;  1YTN A;  1YPT A;  2I6J A;  4C12 A;  1YWF A;  1XBO A;  1OHD A;  5KAC A;  1Q1M A;  2HVL A;  4GE5 A;  2B4O A;  1ZCL A;  2WGP A;  2SHP A;  2NT2 A;  1M3G A;  2VOS A;  2H03 A;  5MMZ B;  2Y1O A;  5EHP A;  5BZX A;  4NX8 A;  1G1F A;  1NZ7 A;  2R0B A;  5KA9 A;  2CNG A;  3HN7 A;  3QCD A;  4HJP A;  1SUG A;  1G4W R;  4GE6 A;  4BUB A;  1YGU A;  4IKC A;  1PH0 A;  2CMB A;  3BRH A;  2H4K A;  2P4D A;  2E0T A;  3EB1 A;  4GRZ A;  5A5F A;  3ZV2 A;  4H1O A;  1Q6M A;  4I8N A;  2Q47 A;  1LQF A;  4QF5 A;  2CFV A;  2UUO A;  2IMG A;  1OEV A;  1OHE A;  2GC5 A;  1J6U A;  2BV5 A;  3EAX A;  3O4S A;  2GP0 A;  3A5J A;  3QCB A;  5IBM A;  2ESB A;  2P6X A;  3U96 A;  1Q6T A;  2I3R A;  3S4O A;  5KA8 A;  4CVL A;  1J4X A;  3QKP A;  4RH5 A;  4NYH A;  4JBC A;  4B04 A;  1RXD A;  1PTY A;  2FH7 A;  2HNP A;  3BLU A;  3SR9 A;  2GCA A;  2J16 B;  3QCG A;  1BZH A;  3I36 A;  4R30 A;  4RI5 A;  4WU2 A;  1UAG A;  3ZM6 A;  1PTU A;  4GE2 A;  2H02 A;  2B4S A;  4R0S A;  1U25 A;  3AWF A;  2QBQ A;  4OHE A;  1GQQ A;  3MOZ A;  1JBW A;  2F6W A;  3RO1 A;  2FJM A;  1C88 A;  3EZZ A;  4Z6B A;  1W7K A;  2F6T A;  2WJP A;  1ONZ A;  1YZ4 A;  2XPC A;  2CM3 A;  1WCH A;  1EEO A;  2CM8 A;  4UAG A;  5BX1 A;  5HDE A;  2HXP A;  2VOR A;  4WU3 A;  2AM2 A;  3I7Z A;  2I42 A;  3B7O A;  4QBE A;  1QZ0 A;  2HC2 A;  3V0H A;  2VEV A;  3F41 A;  1OEO X;  2B07 A;  1NWE A;  1NWL A;  2JFG A;  2OOQ A;  4JMK A;  5K23 A;  2GWO A;  2NV5 A;  3V0G A;  2BIJ A;  1G7G A;  2JFH A;  2I4E A;  3QKQ A;  3V0F A;  3S3E A;  1C86 A;  2F00 A;  4PYH A;  3M4U A;  4OHH A;  1YFO A;  1C84 A;  1U24 A;  1XXP A;  2I6O A;  3MVN A;  1E0D A;  2PBN A;  2VTD A;  4QUM A;  5EHR A;  5J8R A;  1T49 A;  4KYR A;  2UUP A;  4RH9 A;  1PTV A;  2RF6 A;  3GXG A;  5KA0 A;  3NME A;  1OET A;  2M3V A;  2CM7 A;  1JLN A;  2QCT A;  3QCI A;  2Y2F A;  2FJN A;  2OUD A;  1EEN A;  4ERC A;  2ZN7 A;  3ZMQ A;  1W78 A;  2F6Z A;  2VEW A;  2GC6 A;  3PS5 A;  5GTJ A;  2QCJ A;  3ZM1 A;  2B49 A;  4NND A;  4RI4 A;  4WTY A;  3F81 A;  5KA7 A;  2JJD A;  4YR8 B;  1GWZ A;  3AWG A;  2C7S A;  1Q6J A;  2QBS A;  3BLT A;  1JF7 A;  4R0T A;  4ZRT A;  5BUG A;  3ZM2 A;  2PT0 A;  3AWE A;  5A5E A;  1C85 A;  1BZC A;  3QCC A;  3F9A A;  3V0I A;  2AHS A;  3D42 A;  2VEY A;  4PVG A;  2B3O A;  1WAX A;  3D9C A;  2PI7 A;  2BGD A;  2OZ5 A;  2CNE A;  2CNH A;  4Y2E A;  5LXQ B;  4GFV A;  1OEM X;  2ZMM A;  1P15 A;  3OMH A;  3GXH A;  3ZL8 A;  3OLR A;  4GS0 A;  4HJQ A;  2GCB A;  2PQ5 A;  3V0D A;  1ZZW A;  2H4V A;  1NNY A;  3SME A;  2NLK A;  4CVM A;  3A5K A;  3O5X A;  3ZM5 A;  2CNF A;  2I6M A;  3O4U A;  1P3D A;  4GWF A;  2VTE A;  3D1Q A;  4BJO A;  1OES A;  2HY3 A;  4OHL A;  4QAP A;  3I80 A;  5KAA A;  4J51 A;  3QCL A;  1BZJ A;  1V3A A;  4HV4 A;  2NT7 A;  1ZCK A;  1C87 A;  1Q6N A;  3S4E A;  2Q05 A;  3ZM0 A;  2AZR A;  4KYQ A;  1O5Z A;  3F9B A;  4GRY A;  4GFU A;  2C46 A;  1PA1 A;  1GQY A;  1ZC0 A;  3QCE A;  1WRM A;  1P31 A;  4KI9 A;  4YAA A;  4QUN A;  1G4U S;  2I3U A;  2CMC A;  4ZN5 A;  3V0E A;  2DXP A;  1OHC A;  1ECV A;  5KA2 A;  1YTW A;  1FQ1 A;  2F6F A;  3LK7 A;  3O4T A;  2HNQ A;  3N2A A;  1Q6P A;  2H4G A;  3QCZ A;  3QCF A;  2I6I A;  4D3P A;  5K25 A;  2QDM A;  1PYN A;  1L8G A;  2I75 A;  2CNI A;  1X24 A;  3F99 A;  2A3K A;  2F6Y A;  1FPR A;  2F46 A;  4Y14 A;  2UAG A;  4DGP A;  2WTZ A;  3MOW A;  2J16 A;  3D1O A;  2BGE A;  3D1H A;  1E8C A;  3LJ8 A;  3H2X A;  1D5R A;  2I5X A;  2Y66 A;  3D44 A;  1NL9 A;  1GG4 A;  3QCN A;  1FPZ A;  2G59 A;  1RPM A;  2CJZ A;  3CM3 A;  4OHI A;  2HC1 A;  1R6H A;  3QCM A;  1T48 A;  2G6Z A;  1LAR A;  3N0A A;  2AM1 A;  2BZL A;  5K9W A;  2OC3 A;  1ONY A;  1I57 A;  1LYV A;  4C13 A;  1G1G A;  4ICZ A;  4H34 A;  1KAV A;  5KAD A;  1JBV A;  1L8K A;  3RGQ A;  3PYZ A;  3S3H A;  1KAK A;  4JMJ A;  2B4U A;  5KA1 A;  1NO6 A;  2GJT A;  3CWE A;  1PTT A;  3QCJ A;  5AWX A;  3S3F A;  2QDP A;  3BM8 A; 
#chains in the Genus database with same CATH homology
 1XM2 A;  4D3R A;  2I4H A;  2H04 A;  2I6P A;  1VHR A;  5IBS A;  2A8B A;  2PSZ A;  2NTA A;  1C83 A;  1YN9 A;  1G1H A;  1I9T A;  1PXH A;  3V0J A;  2MBC A;  1QXK A;  3RGO A;  5I6V A;  1T4J A;  4JNB A;  3ZM3 A;  4OHD A;  1YGR A;  2PA5 A;  2F71 A;  1PA9 A;  4QAH A;  4D3Q A;  1I9S A;  1MKP A;  2Y96 A;  2I1Y A;  5KA4 A;  5K9V A;  1G7F A;  4ZI4 A;  5KAB A;  4AZ1 A;  1XXV A;  3O3L A;  3MMJ A;  1AAX A;  3RZ2 A;  3QCH A;  4RDD A;  4S0G A;  2B4P A;  1GFY A;  4NWF A;  2VEX A;  3S3K A;  4MBB A;  4DGX A;  5BZZ A;  2HCM A;  2F6V A;  2QDC A;  3ZMP A;  4NWG A;  2YDU A;  5K22 A;  4BPC A;  2NZ6 A;  2F70 A;  2QBP A;  2QEP A;  2QBR A;  1YTS A;  5K24 A;  5M43 A;  1U26 A;  3EMU A;  2VEU A;  4HRF A;  3EU0 A;  2J17 A;  1OEU A;  4TVV A;  1XRI A;  4WOH A;  4RHG A;  4QBW A;  2CM2 A;  1A5Y A;  3QCK A;  1Q6S A;  2HB1 A;  4RKK A;  5KA3 A;  2I4G A;  2CMA A;  1YTN A;  1YPT A;  2I6J A;  1YWF A;  1XBO A;  1OHD A;  5KAC A;  1Q1M A;  2HVL A;  4GE5 A;  2B4O A;  1ZCL A;  2WGP A;  2SHP A;  2NT2 A;  1M3G A;  5MMZ B;  2H03 A;  5EHP A;  5BZX A;  4NX8 A;  1G1F A;  1NZ7 A;  2R0B A;  5KA9 A;  2CNG A;  3QCD A;  4HJP A;  1SUG A;  1G4W R;  4GE6 A;  1YGU A;  4IKC A;  1PH0 A;  2CMB A;  3BRH A;  2H4K A;  2P4D A;  2E0T A;  3EB1 A;  4GRZ A;  3ZV2 A;  4H1O A;  1Q6M A;  4I8N A;  2Q47 A;  1LQF A;  2CFV A;  2IMG A;  1OEV A;  1OHE A;  2BV5 A;  3EAX A;  3O4S A;  2GP0 A;  3A5J A;  3QCB A;  5IBM A;  2ESB A;  2P6X A;  3U96 A;  1Q6T A;  2I3R A;  3S4O A;  5KA8 A;  1J4X A;  3QKP A;  4RH5 A;  4NYH A;  4JBC A;  4B04 A;  1RXD A;  1PTY A;  2FH7 A;  2HNP A;  3BLU A;  3SR9 A;  2J16 B;  3QCG A;  1BZH A;  3I36 A;  4R30 A;  4RI5 A;  4WU2 A;  1PTU A;  4GE2 A;  2H02 A;  2B4S A;  4R0S A;  1U25 A;  3AWF A;  2QBQ A;  4OHE A;  3MOZ A;  2F6W A;  3RO1 A;  2FJM A;  1C88 A;  3EZZ A;  4Z6B A;  2F6T A;  1ONZ A;  1YZ4 A;  2CM3 A;  1WCH A;  1EEO A;  2CM8 A;  5BX1 A;  5HDE A;  2HXP A;  4WU3 A;  3I7Z A;  2I42 A;  3B7O A;  4QBE A;  1QZ0 A;  2HC2 A;  3V0H A;  2VEV A;  3F41 A;  1OEO X;  2B07 A;  1NWE A;  1NWL A;  2OOQ A;  4JMK A;  5K23 A;  2GWO A;  2NV5 A;  3V0G A;  2BIJ A;  1G7G A;  2I4E A;  3QKQ A;  3V0F A;  3S3E A;  1C86 A;  4PYH A;  3M4U A;  4OHH A;  1YFO A;  1C84 A;  1U24 A;  1XXP A;  2I6O A;  2PBN A;  5EHR A;  4QUM A;  5J8R A;  1T49 A;  4KYR A;  4RH9 A;  1PTV A;  2RF6 A;  3GXG A;  5KA0 A;  3NME A;  1OET A;  2M3V A;  2CM7 A;  1JLN A;  2QCT A;  3QCI A;  2Y2F A;  2FJN A;  2OUD A;  1EEN A;  4ERC A;  2ZN7 A;  3ZMQ A;  2F6Z A;  2VEW A;  3PS5 A;  5GTJ A;  2QCJ A;  3ZM1 A;  2B49 A;  4NND A;  4RI4 A;  4WTY A;  3F81 A;  5KA7 A;  2JJD A;  4YR8 B;  1GWZ A;  3AWG A;  2C7S A;  1Q6J A;  2QBS A;  3BLT A;  1JF7 A;  4R0T A;  4ZRT A;  5BUG A;  3ZM2 A;  2PT0 A;  3AWE A;  1C85 A;  1BZC A;  3QCC A;  3F9A A;  3V0I A;  2AHS A;  3D42 A;  2VEY A;  4PVG A;  2B3O A;  1WAX A;  3D9C A;  2PI7 A;  2BGD A;  2OZ5 A;  2CNE A;  2CNH A;  4Y2E A;  5LXQ B;  4GFV A;  1OEM X;  2ZMM A;  1P15 A;  3OMH A;  3GXH A;  3OLR A;  4GS0 A;  4HJQ A;  2PQ5 A;  3V0D A;  1ZZW A;  2H4V A;  1NNY A;  3SME A;  2NLK A;  3A5K A;  3O5X A;  2CNF A;  2I6M A;  3O4U A;  4GWF A;  3D1Q A;  4BJO A;  1OES A;  2HY3 A;  4OHL A;  4QAP A;  3I80 A;  5KAA A;  4J51 A;  3QCL A;  1BZJ A;  1V3A A;  2NT7 A;  1ZCK A;  1C87 A;  1Q6N A;  3S4E A;  2Q05 A;  3ZM0 A;  2AZR A;  4KYQ A;  3F9B A;  4GRY A;  4GFU A;  2C46 A;  1PA1 A;  1ZC0 A;  3QCE A;  1WRM A;  4KI9 A;  4YAA A;  4QUN A;  1G4U S;  2I3U A;  2CMC A;  4ZN5 A;  3V0E A;  2DXP A;  1OHC A;  1ECV A;  5KA2 A;  1YTW A;  1FQ1 A;  2F6F A;  3O4T A;  2HNQ A;  1Q6P A;  2H4G A;  3QCF A;  2I6I A;  4D3P A;  5K25 A;  2QDM A;  1PYN A;  1L8G A;  2I75 A;  2CNI A;  1X24 A;  3F99 A;  2A3K A;  2F6Y A;  1FPR A;  2F46 A;  4Y14 A;  4DGP A;  3MOW A;  2J16 A;  3D1O A;  2BGE A;  3D1H A;  3LJ8 A;  3H2X A;  1D5R A;  2I5X A;  3D44 A;  1NL9 A;  3QCN A;  1FPZ A;  2G59 A;  1RPM A;  2CJZ A;  3CM3 A;  4OHI A;  2HC1 A;  1R6H A;  3QCM A;  1T48 A;  2G6Z A;  1LAR A;  3N0A A;  2BZL A;  5K9W A;  2OC3 A;  1ONY A;  1I57 A;  1LYV A;  1G1G A;  4ICZ A;  4H34 A;  1KAV A;  5KAD A;  1L8K A;  3RGQ A;  3S3H A;  1KAK A;  4JMJ A;  2B4U A;  5KA1 A;  1NO6 A;  2GJT A;  3CWE A;  1PTT A;  3QCJ A;  5AWX A;  3S3F A;  2QDP A;  3BM8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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