2QBUA

Crystal structure of methanothermobacter thermautotrophicus cbil
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
228
structure length
228
Chain Sequence
MHGKLIGVGVGPGDSELLTLRAVNVLRSVPVICAPRSSSERESIALSIVEDILTERRDGCRILDPVFPMTDDRDELESHWDSAARMVAAELEDGRDVAFITLGDPSIYSTFSYLQQRIEDMGFKTEMVPGVTSFTACAATAGRTLVEGDEILLVVPRVDDRFERVLRDVDACVIMKTSRHGRRAMEVVESDPRGKDVVSVANCSMDDEVVERGFASGGGYLATTLVRF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Elucidation of substrate specificity in the cobalamin (vitamin B12) biosynthetic methyltransferases. Structure and function of the C20 methyltransferase (CbiL) from Methanothermobacter thermautotrophicus.
pubmed doi rcsb
source organism Methanothermobacter thermautotrophicus
molecule tags Transferase
molecule keywords Precorrin-2 methyltransferase
total genus 64
structure length 228
sequence length 228
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2qbuA02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2qbuA01
2DXWA 2DSIA 2EHCA 2EEQA 1WYZA 2P6LA 3NEIA 2EKAA 2P6IA 2E17A 2EH2A 2EK3A 3NDCA 2EGLA 2QBUA 2CBFA 2DV5A 2EL3A 2EMRA 3HH1A 2ED3A 2E8SA 1VCEA 2PCKA 1PJTA 2EJZA 1VHVA 2P9DA 2EK7A 2ELDA 3ND1A 2ELEA 1WNGA 2DV3A 2E8QA 2PB6A 2OWGA 2OWKA 2PB4A 2DV4A 2EH5A 2EJJA 2E0KA 2BB3A 2ED5A 2DEKA 2E16A 2EGSA 3I4TA 2Z6RA 2DV7A 3NUTA 2EHLA 2HUXA 2PCIA 2HUQA 2PCHA 1PJQA 2ZVBA 4E16A 5HW4A 2P2XA 2E4RA 2EK2A 2PCAA 1V9AA 2E0NA 1PJSA 2E8RA 2DSGA 2EH4A 2PCGA 2EL2A 2E08A 1S4DA 2EK4A 2P5CA 1CBFA 2OWFA 2HUVA 3FQ6A 2EJKA 2OWUA 2E7RA 2NPNA 1WDEA 2HUTA 1VA0A 2OWVA 2DXXA 3KWPA 2EGBA 2EMUA 2E8HA 2EL0A 2YBOA 2P5FA 2E07A 2E15A 2EN5A 2E4NA 2P6DA 2ZVCA 1VE2A 2HR8A 2DXVA 2YBQA 2PCMA 2ENIA 2PB5A 2DSHA 3FFYA 2P6KA 2EL1A
chains in the Genus database with same CATH superfamily
3ZGLA 2DXWA 2DSIA 2EHCA 2EEQA 3TIXB 1WYZA 2P6LA 3NEIA 3KEMA 3F7TA 2EKAA 2P6IA 3UV6A 2E17A 2EH2A 2EK3A 3NDCA 3T0FA 2EGLA 2QBUA 2CBFA 3ZGNA 3KEFA 2DV5A 2EL3A 2EMRA 3HH1A 2ED3A 2E8SA 1VCEA 2PCKA 1PJTA 2EJZA 1VHVA 2P9DA 2EK7A 2ELDA 3ND1A 2ELEA 1WNGA 3KE9A 2DV3A 2E8QA 2PB6A 4H4CA 2OWGA 2OWKA 4MV5A 2PB4A 2DV4A 4H4DA 2EH5A 4MUYA 2EJJA 2E0KA 2BB3A 2ED5A 2DEKA 3UV7A 2E16A 3SZUA 2EGSA 3I4TA 2Z6RA 2DV7A 3NUTA 2EHLA 2HUXA 3UTCA 2PCIA 2HUQA 2PCHA 1PJQA 2ZVBA 4E16A 5HW4A 2P2XA 3SZOA 2E4RA 2EK2A 2PCAA 1V9AA 2E0NA 3SZLA 4EB3A 1PJSA 2E8RA 2DSGA 2EH4A 3LMMA 2PCGA 2EL2A 2E08A 3UTDA 1S4DA 2EK4A 2P5CA 1CBFA 2KYYA 2OWFA 3URKA 2HUVA 3FQ6A 2EJKA 2OWUA 2E7RA 2NPNA 1WDEA 2HUTA 1VA0A 2OWVA 3KE8A 2DXXA 3KWPA 2EGBA 3DNFA 3T0GA 2EMUA 2E8HA 2EL0A 2YBOA 2P5FA 4MUXA 2E07A 2E15A 3UWMA 2EN5A 4MV0A 2E4NA 2P6DA 3KELA 2ZVCA 1VE2A 4N7BA 2HR8A 2DXVA 2YBQA 2PCMA 4H4EA 2ENIA 2PB5A 2DSHA 3FFYA 2P6KA 3UV3A 2EL1A
chains in the Genus database with same CATH topology
3ZGLA 2DXWA 2DSIA 2EHCA 2EEQA 3TIXB 1WYZA 2P6LA 3NEIA 3KEMA 3F7TA 2EKAA 2P6IA 3UV6A 2E17A 2EH2A 2EK3A 3NDCA 3T0FA 2EGLA 2QBUA 2CBFA 3ZGNA 3KEFA 2DV5A 2EL3A 2EMRA 3HH1A 2ED3A 2E8SA 1VCEA 2PCKA 1PJTA 2EJZA 1VHVA 2P9DA 2EK7A 2ELDA 3ND1A 2ELEA 1WNGA 3KE9A 2DV3A 2E8QA 2PB6A 4H4CA 2OWGA 2OWKA 4MV5A 2PB4A 2DV4A 4H4DA 2EH5A 4MUYA 2EJJA 2E0KA 2BB3A 2ED5A 2DEKA 3UV7A 2E16A 3SZUA 2EGSA 3I4TA 2Z6RA 2DV7A 3NUTA 2EHLA 2HUXA 3UTCA 2PCIA 2HUQA 2PCHA 1PJQA 2ZVBA 4E16A 5HW4A 2P2XA 3SZOA 2E4RA 2EK2A 2PCAA 1V9AA 2E0NA 3SZLA 4EB3A 1PJSA 2E8RA 2DSGA 2EH4A 3LMMA 2PCGA 2EL2A 2E08A 3UTDA 1S4DA 2EK4A 2P5CA 1CBFA 2KYYA 2OWFA 3URKA 2HUVA 3FQ6A 2EJKA 2OWUA 2E7RA 2NPNA 1WDEA 2HUTA 1VA0A 2OWVA 3KE8A 2DXXA 3KWPA 2EGBA 3DNFA 3T0GA 2EMUA 2E8HA 2EL0A 2YBOA 2P5FA 4MUXA 2E07A 2E15A 3UWMA 2EN5A 4MV0A 2E4NA 2P6DA 3KELA 2ZVCA 1VE2A 4N7BA 2HR8A 2DXVA 2YBQA 2PCMA 4H4EA 2ENIA 2PB5A 2DSHA 3FFYA 2P6KA 3UV3A 2EL1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DXW A;  2DSI A;  2EHC A;  2EEQ A;  1WYZ A;  2P6L A;  3NEI A;  2EKA A;  2P6I A;  2E17 A;  2EH2 A;  2EK3 A;  3NDC A;  2EGL A;  2QBU A;  2CBF A;  2DV5 A;  2EL3 A;  2EMR A;  3HH1 A;  2ED3 A;  2E8S A;  1VCE A;  2PCK A;  1PJT A;  2EJZ A;  1VHV A;  2P9D A;  2EK7 A;  2ELD A;  3ND1 A;  2ELE A;  1WNG A;  2DV3 A;  2E8Q A;  2PB6 A;  2OWG A;  2OWK A;  2PB4 A;  2DV4 A;  2EH5 A;  2EJJ A;  2E0K A;  2BB3 A;  2ED5 A;  2DEK A;  2E16 A;  2EGS A;  3I4T A;  2Z6R A;  2DV7 A;  3NUT A;  2EHL A;  2HUX A;  2PCI A;  2HUQ A;  2PCH A;  1PJQ A;  2ZVB A;  4E16 A;  5HW4 A;  2P2X A;  2E4R A;  2EK2 A;  2PCA A;  1V9A A;  2E0N A;  1PJS A;  2E8R A;  2DSG A;  2EH4 A;  2PCG A;  2EL2 A;  2E08 A;  1S4D A;  2EK4 A;  2P5C A;  1CBF A;  2OWF A;  2HUV A;  3FQ6 A;  2EJK A;  2OWU A;  2E7R A;  2NPN A;  1WDE A;  2HUT A;  1VA0 A;  2OWV A;  2DXX A;  3KWP A;  2EGB A;  2EMU A;  2E8H A;  2EL0 A;  2YBO A;  2P5F A;  2E07 A;  2E15 A;  2EN5 A;  2E4N A;  2P6D A;  2ZVC A;  1VE2 A;  2HR8 A;  2DXV A;  2YBQ A;  2PCM A;  2ENI A;  2PB5 A;  2DSH A;  3FFY A;  2P6K A;  2EL1 A; 
#chains in the Genus database with same CATH topology
 3ZGL A;  2DXW A;  2DSI A;  2EHC A;  2EEQ A;  3TIX B;  1WYZ A;  2P6L A;  3NEI A;  3KEM A;  3F7T A;  2EKA A;  2P6I A;  3UV6 A;  2E17 A;  2EH2 A;  2EK3 A;  3NDC A;  3T0F A;  2EGL A;  2QBU A;  2CBF A;  3ZGN A;  3KEF A;  2DV5 A;  2EL3 A;  2EMR A;  3HH1 A;  2ED3 A;  2E8S A;  1VCE A;  2PCK A;  1PJT A;  2EJZ A;  1VHV A;  2P9D A;  2EK7 A;  2ELD A;  3ND1 A;  2ELE A;  1WNG A;  3KE9 A;  2DV3 A;  2E8Q A;  2PB6 A;  4H4C A;  2OWG A;  2OWK A;  4MV5 A;  2PB4 A;  2DV4 A;  4H4D A;  2EH5 A;  4MUY A;  2EJJ A;  2E0K A;  2BB3 A;  2ED5 A;  2DEK A;  3UV7 A;  2E16 A;  3SZU A;  2EGS A;  3I4T A;  2Z6R A;  2DV7 A;  3NUT A;  2EHL A;  2HUX A;  3UTC A;  2PCI A;  2HUQ A;  2PCH A;  1PJQ A;  2ZVB A;  4E16 A;  5HW4 A;  2P2X A;  3SZO A;  2E4R A;  2EK2 A;  2PCA A;  1V9A A;  2E0N A;  3SZL A;  4EB3 A;  1PJS A;  2E8R A;  2DSG A;  2EH4 A;  3LMM A;  2PCG A;  2EL2 A;  2E08 A;  3UTD A;  1S4D A;  2EK4 A;  2P5C A;  1CBF A;  2KYY A;  2OWF A;  3URK A;  2HUV A;  3FQ6 A;  2EJK A;  2OWU A;  2E7R A;  2NPN A;  1WDE A;  2HUT A;  1VA0 A;  2OWV A;  3KE8 A;  2DXX A;  3KWP A;  2EGB A;  3DNF A;  3T0G A;  2EMU A;  2E8H A;  2EL0 A;  2YBO A;  2P5F A;  4MUX A;  2E07 A;  2E15 A;  3UWM A;  2EN5 A;  4MV0 A;  2E4N A;  2P6D A;  3KEL A;  2ZVC A;  1VE2 A;  4N7B A;  2HR8 A;  2DXV A;  2YBQ A;  2PCM A;  4H4E A;  2ENI A;  2PB5 A;  2DSH A;  3FFY A;  2P6K A;  3UV3 A;  2EL1 A; 
#chains in the Genus database with same CATH homology
 3ZGL A;  2DXW A;  2DSI A;  2EHC A;  2EEQ A;  3TIX B;  1WYZ A;  2P6L A;  3NEI A;  3KEM A;  3F7T A;  2EKA A;  2P6I A;  3UV6 A;  2E17 A;  2EH2 A;  2EK3 A;  3NDC A;  3T0F A;  2EGL A;  2QBU A;  2CBF A;  3ZGN A;  3KEF A;  2DV5 A;  2EL3 A;  2EMR A;  3HH1 A;  2ED3 A;  2E8S A;  1VCE A;  2PCK A;  1PJT A;  2EJZ A;  1VHV A;  2P9D A;  2EK7 A;  2ELD A;  3ND1 A;  2ELE A;  1WNG A;  3KE9 A;  2DV3 A;  2E8Q A;  2PB6 A;  4H4C A;  2OWG A;  2OWK A;  4MV5 A;  2PB4 A;  2DV4 A;  4H4D A;  2EH5 A;  4MUY A;  2EJJ A;  2E0K A;  2BB3 A;  2ED5 A;  2DEK A;  3UV7 A;  2E16 A;  3SZU A;  2EGS A;  3I4T A;  2Z6R A;  2DV7 A;  3NUT A;  2EHL A;  2HUX A;  3UTC A;  2PCI A;  2HUQ A;  2PCH A;  1PJQ A;  2ZVB A;  4E16 A;  5HW4 A;  2P2X A;  3SZO A;  2E4R A;  2EK2 A;  2PCA A;  1V9A A;  2E0N A;  3SZL A;  4EB3 A;  1PJS A;  2E8R A;  2DSG A;  2EH4 A;  3LMM A;  2PCG A;  2EL2 A;  2E08 A;  3UTD A;  1S4D A;  2EK4 A;  2P5C A;  1CBF A;  2KYY A;  2OWF A;  3URK A;  2HUV A;  3FQ6 A;  2EJK A;  2OWU A;  2E7R A;  2NPN A;  1WDE A;  2HUT A;  1VA0 A;  2OWV A;  3KE8 A;  2DXX A;  3KWP A;  2EGB A;  3DNF A;  3T0G A;  2EMU A;  2E8H A;  2EL0 A;  2YBO A;  2P5F A;  4MUX A;  2E07 A;  2E15 A;  3UWM A;  2EN5 A;  4MV0 A;  2E4N A;  2P6D A;  3KEL A;  2ZVC A;  1VE2 A;  4N7B A;  2HR8 A;  2DXV A;  2YBQ A;  2PCM A;  4H4E A;  2ENI A;  2PB5 A;  2DSH A;  3FFY A;  2P6K A;  3UV3 A;  2EL1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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