2QEXE

Negamycin binds to the wall of the nascent chain exit tunnel of the 50s ribosomal subunit
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Negamycin binds to the wall of the nascent chain exit tunnel of the 50S ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 41
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2007-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 2qexE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 2qexE01
4UY8G 5HL7E 1M90G 1M1KG 1YJ9E 1VQ8E 3J7ZG 3CCEE 1VQNE 3I56E 1RL6A 2QEXE 3CC2E 3CCJE 3CCLE 1VQ7E 3CCME 1N8RG 1YHQE 3CCRE 3I55E 4WCEE 1JJ2E 4IO9E 3PIOE 5JVHE 1YI2E 1VQOE 3DLLE 2ZJQE 1VQ9E 1VQLE 1VQ6E 3PIPE 1Q7YG 1VQPE 1QVFE 1VQKE 3OW2E 5AN9B 5GAGG 4U67E 3CPWE 1Q86G 1QVGE 1YJWE 1KQSE 2QA4E 3CMAE 5JVGE 1YITE 3G6EE 4IOAE 4WF9E 3CF5E 3CXCE 2ZJRE 4WFNE 3CD6E 1VQ5E 1VQME 1S72E 5DM7E 1VQ4E 3CCVE 4IOCE 3CCSE 5GAEG 2ZJPE 5GADG 3CMEE 1YIJE 1K9MG 5MLCH 1Q82G 3CCQE 5DM6E 2OTLE 1KC8G 1YJNE 3CC4E 3G71E 2OTJE 1W2BE 2CQLA 1K73G 1NJIG 3CC7E 1K8AG 4WFAE 5H1SI 1Q81G 5GAHG 4WFBE 3CCUE 1KD1G 3G4SE
chains in the Genus database with same CATH superfamily
4UY8G 5HL7E 1M90G 1M1KG 5B10O 1YJ9E 1VQ8E 2AF5A 3J7ZG 2OYBO 3CCEE 1VQNE 3I56E 1RL6A 2QEXE 3CC2E 2OY5O 2I5VO 5B11O 3CCJE 3CCLE 1VQ7E 3CCME 1N8RG 3EC5A 1YHQE 3CKFA 3CCRE 3I55E 1RJLC 4WCEE 1JJ2E 4IO9E 2FKGA 3PIOE 5B3MO 5JVHE 1YI2E 2HKDA 1VQOE 3DLLE 2OL6O 2ZJQE 1VQ9E 1VQLE 1VQ6E 3PIPE 3CKGA 1Q7YG 1VQPE 1QVFE 1VQKE 3OW2E 5AN9B 5GAGG 4U67E 3CPWE 1Q86G 1QVGE 1YJWE 1KQSE 2I5ZO 2QA4E 3CMAE 5B2AO 5JVGE 1YITE 3G6EE 2OY1O 4IOAE 2FKJA 2OL7A 1P4PA 4WF9E 3CF5E 3CXCE 2ZJRE 4WFNE 3CD6E 2PI3O 1VQ5E 1VQME 1S72E 5DM7E 1VQ4E 1OSPO 3CCVE 4IOCE 3CCSE 3IGEA 5GAEG 2ZJPE 5GADG 3CMEE 1YIJE 1K9MG 2OY7A 5MLCH 1Q82G 3CCQE 5DM6E 2OTLE 1FJ1E 3AUMO 1KC8G 1YJNE 3CC4E 3IG9A 3G71E 2OTJE 1W2BE 2CQLA 2OL8O 1K73G 1NJIG 2OY8A 3CC7E 1K8AG 4WFAE 5H1SI 1Q81G 5GAHG 4WFBE 3CCUE 2G8CO 1KD1G 3G4SE
chains in the Genus database with same CATH topology
4UY8G 5HL7E 1M90G 1M1KG 1YJ9E 1VQ8E 3J7ZG 3CCEE 1VQNE 3I56E 1RL6A 2QEXE 3CC2E 3CCJE 3CCLE 1VQ7E 3CCME 1N8RG 1YHQE 3CCRE 3I55E 4WCEE 1JJ2E 4IO9E 3PIOE 5JVHE 1YI2E 1VQOE 3DLLE 2ZJQE 1VQ9E 1VQLE 1VQ6E 3PIPE 1Q7YG 1VQPE 1QVFE 1VQKE 3OW2E 5AN9B 5GAGG 4U67E 3CPWE 1Q86G 1QVGE 1YJWE 1KQSE 2QA4E 3CMAE 5JVGE 1YITE 3G6EE 4IOAE 4WF9E 3CF5E 3CXCE 2ZJRE 4WFNE 3CD6E 1VQ5E 1VQME 1S72E 5DM7E 1VQ4E 3CCVE 4IOCE 3CCSE 5GAEG 2ZJPE 5GADG 3CMEE 1YIJE 1K9MG 5MLCH 1Q82G 3CCQE 5DM6E 2OTLE 1KC8G 1YJNE 3CC4E 3G71E 2OTJE 1W2BE 2CQLA 1K73G 1NJIG 3CC7E 1K8AG 4WFAE 5H1SI 1Q81G 5GAHG 4WFBE 3CCUE 1KD1G 3G4SE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UY8 G;  5HL7 E;  1M90 G;  1M1K G;  1YJ9 E;  1VQ8 E;  3J7Z G;  3CCE E;  1VQN E;  3I56 E;  1RL6 A;  2QEX E;  3CC2 E;  3CCJ E;  3CCL E;  1VQ7 E;  3CCM E;  1N8R G;  1YHQ E;  3CCR E;  3I55 E;  4WCE E;  1JJ2 E;  4IO9 E;  3PIO E;  5JVH E;  1YI2 E;  1VQO E;  3DLL E;  2ZJQ E;  1VQ9 E;  1VQL E;  1VQ6 E;  3PIP E;  1Q7Y G;  1VQP E;  1QVF E;  1VQK E;  3OW2 E;  5AN9 B;  5GAG G;  4U67 E;  3CPW E;  1Q86 G;  1QVG E;  1YJW E;  1KQS E;  2QA4 E;  3CMA E;  5JVG E;  1YIT E;  3G6E E;  4IOA E;  4WF9 E;  3CF5 E;  3CXC E;  2ZJR E;  4WFN E;  3CD6 E;  1VQ5 E;  1VQM E;  1S72 E;  5DM7 E;  1VQ4 E;  3CCV E;  4IOC E;  3CCS E;  5GAE G;  2ZJP E;  5GAD G;  3CME E;  1YIJ E;  1K9M G;  5MLC H;  1Q82 G;  3CCQ E;  5DM6 E;  2OTL E;  1KC8 G;  1YJN E;  3CC4 E;  3G71 E;  2OTJ E;  1W2B E;  2CQL A;  1K73 G;  1NJI G;  3CC7 E;  1K8A G;  4WFA E;  5H1S I;  1Q81 G;  5GAH G;  4WFB E;  3CCU E;  1KD1 G;  3G4S E; 
#chains in the Genus database with same CATH topology
 4UY8 G;  5HL7 E;  1M90 G;  1M1K G;  5B10 O;  1YJ9 E;  1VQ8 E;  2AF5 A;  3J7Z G;  2OYB O;  3CCE E;  1VQN E;  3I56 E;  1RL6 A;  2QEX E;  3CC2 E;  2OY5 O;  2I5V O;  5B11 O;  3CCJ E;  3CCL E;  1VQ7 E;  3CCM E;  1N8R G;  3EC5 A;  1YHQ E;  3CKF A;  3CCR E;  3I55 E;  1RJL C;  4WCE E;  1JJ2 E;  4IO9 E;  2FKG A;  3PIO E;  5B3M O;  5JVH E;  1YI2 E;  2HKD A;  1VQO E;  3DLL E;  2OL6 O;  2ZJQ E;  1VQ9 E;  1VQL E;  1VQ6 E;  3PIP E;  3CKG A;  1Q7Y G;  1VQP E;  1QVF E;  1VQK E;  3OW2 E;  5AN9 B;  5GAG G;  4U67 E;  3CPW E;  1Q86 G;  1QVG E;  1YJW E;  1KQS E;  2I5Z O;  2QA4 E;  3CMA E;  5B2A O;  5JVG E;  1YIT E;  3G6E E;  2OY1 O;  4IOA E;  2FKJ A;  2OL7 A;  1P4P A;  4WF9 E;  3CF5 E;  3CXC E;  2ZJR E;  4WFN E;  3CD6 E;  2PI3 O;  1VQ5 E;  1VQM E;  1S72 E;  5DM7 E;  1VQ4 E;  1OSP O;  3CCV E;  4IOC E;  3CCS E;  3IGE A;  5GAE G;  2ZJP E;  5GAD G;  3CME E;  1YIJ E;  1K9M G;  2OY7 A;  5MLC H;  1Q82 G;  3CCQ E;  5DM6 E;  2OTL E;  1FJ1 E;  3AUM O;  1KC8 G;  1YJN E;  3CC4 E;  3IG9 A;  3G71 E;  2OTJ E;  1W2B E;  2CQL A;  2OL8 O;  1K73 G;  1NJI G;  2OY8 A;  3CC7 E;  1K8A G;  4WFA E;  5H1S I;  1Q81 G;  5GAH G;  4WFB E;  3CCU E;  2G8C O;  1KD1 G;  3G4S E; 
#chains in the Genus database with same CATH homology
 4UY8 G;  5HL7 E;  1M90 G;  1M1K G;  1YJ9 E;  1VQ8 E;  3J7Z G;  3CCE E;  1VQN E;  3I56 E;  1RL6 A;  2QEX E;  3CC2 E;  3CCJ E;  3CCL E;  1VQ7 E;  3CCM E;  1N8R G;  1YHQ E;  3CCR E;  3I55 E;  4WCE E;  1JJ2 E;  4IO9 E;  3PIO E;  5JVH E;  1YI2 E;  1VQO E;  3DLL E;  2ZJQ E;  1VQ9 E;  1VQL E;  1VQ6 E;  3PIP E;  1Q7Y G;  1VQP E;  1QVF E;  1VQK E;  3OW2 E;  5AN9 B;  5GAG G;  4U67 E;  3CPW E;  1Q86 G;  1QVG E;  1YJW E;  1KQS E;  2QA4 E;  3CMA E;  5JVG E;  1YIT E;  3G6E E;  4IOA E;  4WF9 E;  3CF5 E;  3CXC E;  2ZJR E;  4WFN E;  3CD6 E;  1VQ5 E;  1VQM E;  1S72 E;  5DM7 E;  1VQ4 E;  3CCV E;  4IOC E;  3CCS E;  5GAE G;  2ZJP E;  5GAD G;  3CME E;  1YIJ E;  1K9M G;  5MLC H;  1Q82 G;  3CCQ E;  5DM6 E;  2OTL E;  1KC8 G;  1YJN E;  3CC4 E;  3G71 E;  2OTJ E;  1W2B E;  2CQL A;  1K73 G;  1NJI G;  3CC7 E;  1K8A G;  4WFA E;  5H1S I;  1Q81 G;  5GAH G;  4WFB E;  3CCU E;  1KD1 G;  3G4S E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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