2QFUA

E.coli epsp synthase pro101leu liganded with s3p and glyphosate
Total Genus 161
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
161
sequence length
427
structure length
427
Chain Sequence
MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTALGVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRLLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of glyphosate tolerance resulting from mutations of Pro101 in Escherichia coli 5-enolpyruvylshikimate-3-phosphate synthase.
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords 3-phosphoshikimate 1-carboxyvinyltransferase
total genus 161
structure length 427
sequence length 427
ec nomenclature ec 2.5.1.19: 3-phosphoshikimate 1-carboxyvinyltransferase.
pdb deposition date 2007-06-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00275 EPSP_synthase EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.65.10.10 Alpha Beta Alpha-beta prism UDP-n-acetylglucosamine1-carboxyvinyl-transferase; Chain Enolpyruvate transferase domain 2qfuA02
3.65.10.10 Alpha Beta Alpha-beta prism UDP-n-acetylglucosamine1-carboxyvinyl-transferase; Chain Enolpyruvate transferase domain 2qfuA01
4E7GA 5BUFA 3SG1A 4GFPA 2O0ZA 1MI4A 3SWGA 2PQCA 1Q3GA 3SWAA 3V5VA 3KQAA 2GG6A 5BQ2A 3ZH4A 2QFSA 2RL2A 4R7UA 1X8TA 2Z2CA 1G6SA 1RYWA 3ROIA 3FJXA 1EJDA 5U4HA 1RF4A 3RMTA 2PQDA 2O0EA 1X8RA 3SU9A 3NVSA 2GGDA 4E7CA 3SWQA 3SWEA 5BS5A 2O15A 1YBGA 1P89A 3FK1A 1EYNA 2PQBA 3V4TA 4EGRA 3KR6A 3SWIA 3ISSA 3ZH3A 2GG4A 3SLHA 3UPKA 1RF6A 2O0BA 1DLGA 3FK0A 1RF5A 2PQ9A 3R38A 2QFTA 3TR1A 1EJCA 2GGAA 2YVWA 1NAWA 4E7FA 2QFQA 2O0XA 4N3PA 1Q36A 2RL1A 3LTHA 2O0DA 4ZNDA 1P88A 2QFUA 4EIIA 3SWDA 3VCYA 4E7EA 4FQDA 3SPBA 2AAYA 1G6TA 3TI2A 1UAEA 4E7BA 4E7DA 3KQJA 2BJBA 2AA9A 3FJZA 1A2NA
chains in the Genus database with same CATH superfamily
4E7GA 5BUFA 3SG1A 4GFPA 4O89A 2O0ZA 1MI4A 3SWGA 2PQCA 1Q3GA 3SWAA 3V5VA 3KQAA 2GG6A 5BQ2A 3ZH4A 2QFSA 2RL2A 4R7UA 1X8TA 2Z2CA 1G6SA 1RYWA 3ROIA 3FJXA 1EJDA 5U4HA 1RF4A 3RMTA 2PQDA 2O0EA 3TV1A 3PQVA 1X8RA 3SU9A 3NVSA 2GGDA 4E7CA 3SWQA 3SWEA 5BS5A 2O15A 1YBGA 1P89A 3FK1A 1EYNA 2PQBA 3V4TA 4EGRA 3KR6A 3TW3A 3SWIA 3ISSA 3ZH3A 2GG4A 3SLHA 3UPKA 3TUTA 1RF6A 2O0BA 1DLGA 3FK0A 1RF5A 2PQ9A 3R38A 2QFTA 3TR1A 1QMHA 1EJCA 2GGAA 2YVWA 4CLQA 1NAWA 4E7FA 3TUXA 2QFQA 2O0XA 4N3PA 1Q36A 2RL1A 3LTHA 2O0DA 4ZNDA 1P88A 2QFUA 4EIIA 3SWDA 3VCYA 4E7EA 4FQDA 3SPBA 2AAYA 1G6TA 3TI2A 3KGDA 4O8JA 1UAEA 4E7BA 4E7DA 3KQJA 2BJBA 2AA9A 3FJZA 1QMIA 1A2NA
chains in the Genus database with same CATH topology
4E7GA 5BUFA 3SG1A 4GFPA 2O0ZA 1MI4A 3SWGA 2PQCA 1Q3GA 3SWAA 3V5VA 3KQAA 2GG6A 5BQ2A 3ZH4A 2QFSA 2RL2A 4R7UA 1X8TA 2Z2CA 1G6SA 1RYWA 3ROIA 3FJXA 1EJDA 5U4HA 1RF4A 3RMTA 2PQDA 2O0EA 1X8RA 3SU9A 3NVSA 2GGDA 4E7CA 3SWQA 3SWEA 5BS5A 2O15A 1YBGA 1P89A 3FK1A 1EYNA 2PQBA 3V4TA 4EGRA 3KR6A 3SWIA 3ISSA 3ZH3A 2GG4A 3SLHA 3UPKA 1RF6A 2O0BA 1DLGA 3FK0A 1RF5A 2PQ9A 3R38A 2QFTA 3TR1A 1EJCA 2GGAA 2YVWA 1NAWA 4E7FA 2QFQA 2O0XA 4N3PA 1Q36A 2RL1A 3LTHA 2O0DA 4ZNDA 1P88A 2QFUA 4EIIA 3SWDA 3VCYA 4E7EA 4FQDA 3SPBA 2AAYA 1G6TA 3TI2A 1UAEA 4E7BA 4E7DA 3KQJA 2BJBA 2AA9A 3FJZA 1A2NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E7G A;  5BUF A;  3SG1 A;  4GFP A;  2O0Z A;  1MI4 A;  3SWG A;  2PQC A;  1Q3G A;  3SWA A;  3V5V A;  3KQA A;  2GG6 A;  5BQ2 A;  3ZH4 A;  2QFS A;  2RL2 A;  4R7U A;  1X8T A;  2Z2C A;  1G6S A;  1RYW A;  3ROI A;  3FJX A;  1EJD A;  5U4H A;  1RF4 A;  3RMT A;  2PQD A;  2O0E A;  1X8R A;  3SU9 A;  3NVS A;  2GGD A;  4E7C A;  3SWQ A;  3SWE A;  5BS5 A;  2O15 A;  1YBG A;  1P89 A;  3FK1 A;  1EYN A;  2PQB A;  3V4T A;  4EGR A;  3KR6 A;  3SWI A;  3ISS A;  3ZH3 A;  2GG4 A;  3SLH A;  3UPK A;  1RF6 A;  2O0B A;  1DLG A;  3FK0 A;  1RF5 A;  2PQ9 A;  3R38 A;  2QFT A;  3TR1 A;  1EJC A;  2GGA A;  2YVW A;  1NAW A;  4E7F A;  2QFQ A;  2O0X A;  4N3P A;  1Q36 A;  2RL1 A;  3LTH A;  2O0D A;  4ZND A;  1P88 A;  2QFU A;  4EII A;  3SWD A;  3VCY A;  4E7E A;  4FQD A;  3SPB A;  2AAY A;  1G6T A;  3TI2 A;  1UAE A;  4E7B A;  4E7D A;  3KQJ A;  2BJB A;  2AA9 A;  3FJZ A;  1A2N A; 
#chains in the Genus database with same CATH topology
 4E7G A;  5BUF A;  3SG1 A;  4GFP A;  4O89 A;  2O0Z A;  1MI4 A;  3SWG A;  2PQC A;  1Q3G A;  3SWA A;  3V5V A;  3KQA A;  2GG6 A;  5BQ2 A;  3ZH4 A;  2QFS A;  2RL2 A;  4R7U A;  1X8T A;  2Z2C A;  1G6S A;  1RYW A;  3ROI A;  3FJX A;  1EJD A;  5U4H A;  1RF4 A;  3RMT A;  2PQD A;  2O0E A;  3TV1 A;  3PQV A;  1X8R A;  3SU9 A;  3NVS A;  2GGD A;  4E7C A;  3SWQ A;  3SWE A;  5BS5 A;  2O15 A;  1YBG A;  1P89 A;  3FK1 A;  1EYN A;  2PQB A;  3V4T A;  4EGR A;  3KR6 A;  3TW3 A;  3SWI A;  3ISS A;  3ZH3 A;  2GG4 A;  3SLH A;  3UPK A;  3TUT A;  1RF6 A;  2O0B A;  1DLG A;  3FK0 A;  1RF5 A;  2PQ9 A;  3R38 A;  2QFT A;  3TR1 A;  1QMH A;  1EJC A;  2GGA A;  2YVW A;  4CLQ A;  1NAW A;  4E7F A;  3TUX A;  2QFQ A;  2O0X A;  4N3P A;  1Q36 A;  2RL1 A;  3LTH A;  2O0D A;  4ZND A;  1P88 A;  2QFU A;  4EII A;  3SWD A;  3VCY A;  4E7E A;  4FQD A;  3SPB A;  2AAY A;  1G6T A;  3TI2 A;  3KGD A;  4O8J A;  1UAE A;  4E7B A;  4E7D A;  3KQJ A;  2BJB A;  2AA9 A;  3FJZ A;  1QMI A;  1A2N A; 
#chains in the Genus database with same CATH homology
 4E7G A;  5BUF A;  3SG1 A;  4GFP A;  2O0Z A;  1MI4 A;  3SWG A;  2PQC A;  1Q3G A;  3SWA A;  3V5V A;  3KQA A;  2GG6 A;  5BQ2 A;  3ZH4 A;  2QFS A;  2RL2 A;  4R7U A;  1X8T A;  2Z2C A;  1G6S A;  1RYW A;  3ROI A;  3FJX A;  1EJD A;  5U4H A;  1RF4 A;  3RMT A;  2PQD A;  2O0E A;  1X8R A;  3SU9 A;  3NVS A;  2GGD A;  4E7C A;  3SWQ A;  3SWE A;  5BS5 A;  2O15 A;  1YBG A;  1P89 A;  3FK1 A;  1EYN A;  2PQB A;  3V4T A;  4EGR A;  3KR6 A;  3SWI A;  3ISS A;  3ZH3 A;  2GG4 A;  3SLH A;  3UPK A;  1RF6 A;  2O0B A;  1DLG A;  3FK0 A;  1RF5 A;  2PQ9 A;  3R38 A;  2QFT A;  3TR1 A;  1EJC A;  2GGA A;  2YVW A;  1NAW A;  4E7F A;  2QFQ A;  2O0X A;  4N3P A;  1Q36 A;  2RL1 A;  3LTH A;  2O0D A;  4ZND A;  1P88 A;  2QFU A;  4EII A;  3SWD A;  3VCY A;  4E7E A;  4FQD A;  3SPB A;  2AAY A;  1G6T A;  3TI2 A;  1UAE A;  4E7B A;  4E7D A;  3KQJ A;  2BJB A;  2AA9 A;  3FJZ A;  1A2N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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