2QJCA

Crystal structure of a putative diadenosine tetraphosphatase
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
242
structure length
222
Chain Sequence
YANVVTLPNVTGRVIIVGDIHGCRAQLEDLLRAVSFKQGSDTLVAVGDLVNKGPDSFGVVRLLKRLGAYSVLGNHDAKLLKLVKKLSLAPLAQSIPTDVETYLSQLPHIIRIPAHNVMVAHAGLHPQRPVDRQYEDEVTTMRNLIEKVTLTATEETNDGGKPWASMWRGPETVVFGHDARRGLQEQYKPLAIGLDSRCVYGGRLSAAVFPGGCIISVPGWNG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Diadenosine tetraphosphatase, putative
publication title Structural genomics of protein phosphatases.
pubmed doi rcsb
source organism Trypanosoma brucei
total genus 63
structure length 222
sequence length 242
ec nomenclature ec 3.6.1.41: Bis(5'-nucleosyl)-tetraphosphatase (symmetrical).
pdb deposition date 2007-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 2qjcA00
1S3MA 1XZWA 4KBPA 4XPNA 2Q8UA 3C9FA 1UTEA 2USHA 4FBQA 5J28A 1TCOA 2O8AA 1T70A 4MOYA 4H2BA 5INBA 4NZVA 2R17A 1IT6A 1HP1A 3LL8A 2CV9A 1WAO1 2BCDA 4ORAA 1QHWA 3IVEA 2HYOA 3QG5C 2O8GA 3QFKA 4FCXA 4Q7FA 4UT2A 3THNA 1M63A 4FBKA 3QFNA 2NXFA 3H66A 4LACC 1KBPA 4J6OA 3DSCA 2IE4C 3JYFA 4O4KA 2AHDA 1U32A 3RL4A 3H64A 3K7VC 3HVQA 4O43A 1USHA 4H2IA 2GJUA 2A22A 2ZBMA 4MP0A 1NNWA 3ICFA 2HYPA 3V4YA 2QFPA 4HD0A 3RL5A 2IAEC 4DSYA 4B2OA 5JPEA 1HO5A 2HY1A 2NYMC 1JK7A 1S95A 3AV0A 4JA7A 3IB8A 3CK2A 3IB7A 4ZVZA 5IOHA 3K7WC 4JA9A 1QFCA 1II7A 3N5UA 3QFMA 2DFJA 4H2FA 4H1YP 2P6BA 3H61A 1UF3A 3E7AA 3H69A 2BDXA 3P71C 2Z06A 1OI8A 4V0VA 5JPFA 3H60A 4OR9A 4I5NC 4FBWA 2WDDA 1AUIA 4M0VA 4ZX2A 3AUZA 5EQVA 3H67A 2IE3C 1XM7A 3E7BA 2NPPC 5B8IA 1S70A 1T71A 1Z2WA 4V0XA 3T1IA 2QFRA 4ORBA 3RQZA 4TUIA 1SU1A 4TUGA 2Z1AA 3GVEA 3QFOA 4IL1A 4IYPC 3PSOA 2KKNA 1S3NA 1MF8A 3PSNA 3H63A 2YVTA 3EGHA 4O24A 3H62B 3THOB 1S8EA 3C5WC 4UT3B 4UWQA 3ZU0A 5HPEA 5DNYA 2BQ8X 4WWLA 3RL3A 1OIEA 2QJCA 1HPUA 1FJMA 3DSDA 4H1SA 4LTYA 5GTUA 5C1VA 3KBPA 5F3WA 3IVDA 1G5BA 2WDEA 4V0WA 4ORCA 4LU9A 2Z72A 2XMOA 4DHLA 4MOVA 1W24A 3ZTVA 2JOGA 4H2GA 1OIDA 3FGAC 4G9JA 3EGGA 2WDCA 4KKZA 4DT2A 4O5GA 2NYLC 1WARA 4I5LC 3H68A 1S3LA 4F0ZA 2WDFA 3TGHA 5JJTA 1V73A 4UT3A 4YKEA 3DW8C 1Z2XA
chains in the Genus database with same CATH superfamily
1S3MA 1XZWA 4KBPA 4XPNA 2Q8UA 3C9FA 2DXNA 1UTEA 2USHA 4FBQA 5J28A 1TCOA 2O8AA 1T70A 4MOYA 4H2BA 5INBA 4NZVA 2R17A 1IT6A 1HP1A 3LL8A 2CV9A 1WAO1 2BCDA 4ORAA 2YEQA 2DXLA 1QHWA 3IVEA 2HYOA 3QG5C 2O8GA 3QFKA 4FCXA 4Q7FA 4UT2A 3THNA 1M63A 4FBKA 3QFNA 2NXFA 3H66A 4LACC 1KBPA 4J6OA 3DSCA 2IE4C 3JYFA 4O4KA 2AHDA 1U32A 3RL4A 3H64A 3K7VC 3HVQA 4O43A 1USHA 4H2IA 2GJUA 2A22A 2ZBMA 4MP0A 1NNWA 3ICFA 2HYPA 3E0JA 3V4YA 2QFPA 4HD0A 3RL5A 2IAEC 4DSYA 4B2OA 5JPEA 1HO5A 2HY1A 2NYMC 1JK7A 1S95A 3AV0A 4JA7A 3IB8A 3CK2A 3IB7A 4ZVZA 5IOHA 3K7WC 4JA9A 1QFCA 1II7A 3N5UA 3QFMA 2DFJA 4H2FA 4H1YP 2P6BA 3H61A 1UF3A 3E7AA 3H69A 2BDXA 3P71C 2Z06A 1OI8A 4V0VA 5JPFA 3H60A 4OR9A 4I5NC 4FBWA 2WDDA 1AUIA 4M0VA 4ZX2A 3AUZA 5EQVA 3H67A 2IE3C 1XM7A 3E7BA 2NPPC 5B8IA 1S70A 1T71A 1Z2WA 4V0XA 3T1IA 2QFRA 4ORBA 3RQZA 4TUIA 1SU1A 4TUGA 2Z1AA 3GVEA 3QFOA 4IL1A 4IYPC 3PSOA 2KKNA 1S3NA 1MF8A 3PSNA 3H63A 2YVTA 3EGHA 4O24A 3H62B 3THOB 1S8EA 3C5WC 4UT3B 4UWQA 3ZU0A 5HPEA 5DNYA 2BQ8X 4WWLA 3RL3A 1OIEA 2QJCA 1HPUA 1FJMA 3DSDA 2ZOAA 4H1SA 3D03A 4LTYA 5GTUA 5C1VA 3KBPA 5F3WA 3IVDA 1G5BA 2WDEA 4V0WA 4ORCA 4LU9A 2Z72A 2XMOA 4DHLA 4MOVA 1W24A 3ZTVA 2JOGA 4H2GA 1OIDA 3FGAC 4G9JA 3EGGA 2WDCA 4KKZA 2ZO9B 4DT2A 4O5GA 2NYLC 1WARA 4I5LC 3H68A 1S3LA 4F0ZA 2WDFA 3TGHA 5JJTA 1V73A 4UT3A 4YKEA 3FLOA 3DW8C 1Z2XA
chains in the Genus database with same CATH topology
1S3MA 1XZWA 4KBPA 4XPNA 2Q8UA 3C9FA 2DXNA 1UTEA 2USHA 4FBQA 5J28A 1TCOA 2O8AA 1T70A 4MOYA 4H2BA 5INBA 4NZVA 2R17A 1IT6A 1HP1A 3LL8A 2CV9A 1WAO1 2BCDA 4ORAA 2YEQA 2DXLA 1QHWA 3IVEA 2HYOA 3QG5C 2O8GA 3QFKA 4FCXA 4Q7FA 4UT2A 3THNA 1M63A 4FBKA 3QFNA 2NXFA 3H66A 4LACC 1KBPA 4J6OA 3DSCA 2IE4C 3JYFA 4O4KA 2AHDA 1U32A 3RL4A 3H64A 3K7VC 3HVQA 4O43A 1USHA 4H2IA 2GJUA 2A22A 2ZBMA 4MP0A 1NNWA 3ICFA 2HYPA 3E0JA 3V4YA 2QFPA 4HD0A 3RL5A 2IAEC 4DSYA 4B2OA 5JPEA 1HO5A 2HY1A 2NYMC 1JK7A 1S95A 3AV0A 4JA7A 3IB8A 3CK2A 3IB7A 4ZVZA 5IOHA 3K7WC 4JA9A 1QFCA 1II7A 3N5UA 3QFMA 2DFJA 4H2FA 4H1YP 2P6BA 3H61A 1UF3A 3E7AA 3H69A 2BDXA 3P71C 2Z06A 1OI8A 4V0VA 5JPFA 3H60A 4OR9A 4I5NC 4FBWA 2WDDA 1AUIA 4M0VA 4ZX2A 3AUZA 5EQVA 3H67A 2IE3C 1XM7A 3E7BA 2NPPC 5B8IA 1S70A 1T71A 1Z2WA 4V0XA 3T1IA 2QFRA 4ORBA 3RQZA 4TUIA 1SU1A 4TUGA 2Z1AA 3GVEA 3QFOA 4IL1A 4IYPC 3PSOA 2KKNA 1S3NA 1MF8A 3PSNA 3H63A 2YVTA 3EGHA 4O24A 3H62B 3THOB 1S8EA 3C5WC 4UT3B 4UWQA 3ZU0A 5HPEA 5DNYA 2BQ8X 4WWLA 3RL3A 1OIEA 2QJCA 1HPUA 1FJMA 3DSDA 2ZOAA 4H1SA 3D03A 4LTYA 5GTUA 5C1VA 3KBPA 5F3WA 3IVDA 1G5BA 2WDEA 4V0WA 4ORCA 4LU9A 2Z72A 2XMOA 4DHLA 4MOVA 1W24A 3ZTVA 2JOGA 4H2GA 1OIDA 3FGAC 4G9JA 3EGGA 2WDCA 4KKZA 2ZO9B 4DT2A 4O5GA 2NYLC 1WARA 4I5LC 3H68A 1S3LA 4F0ZA 2WDFA 3TGHA 5JJTA 1V73A 4UT3A 4YKEA 3FLOA 3DW8C 1Z2XA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1S3M A;  1XZW A;  4KBP A;  4XPN A;  2Q8U A;  3C9F A;  1UTE A;  2USH A;  4FBQ A;  5J28 A;  1TCO A;  2O8A A;  1T70 A;  4MOY A;  4H2B A;  5INB A;  4NZV A;  2R17 A;  1IT6 A;  1HP1 A;  3LL8 A;  2CV9 A;  1WAO 1;  2BCD A;  4ORA A;  1QHW A;  3IVE A;  2HYO A;  3QG5 C;  2O8G A;  3QFK A;  4FCX A;  4Q7F A;  4UT2 A;  3THN A;  1M63 A;  4FBK A;  3QFN A;  2NXF A;  3H66 A;  4LAC C;  1KBP A;  4J6O A;  3DSC A;  2IE4 C;  3JYF A;  4O4K A;  2AHD A;  1U32 A;  3RL4 A;  3H64 A;  3K7V C;  3HVQ A;  4O43 A;  1USH A;  4H2I A;  2GJU A;  2A22 A;  2ZBM A;  4MP0 A;  1NNW A;  3ICF A;  2HYP A;  3V4Y A;  2QFP A;  4HD0 A;  3RL5 A;  2IAE C;  4DSY A;  4B2O A;  5JPE A;  1HO5 A;  2HY1 A;  2NYM C;  1JK7 A;  1S95 A;  3AV0 A;  4JA7 A;  3IB8 A;  3CK2 A;  3IB7 A;  4ZVZ A;  5IOH A;  3K7W C;  4JA9 A;  1QFC A;  1II7 A;  3N5U A;  3QFM A;  2DFJ A;  4H2F A;  4H1Y P;  2P6B A;  3H61 A;  1UF3 A;  3E7A A;  3H69 A;  2BDX A;  3P71 C;  2Z06 A;  1OI8 A;  4V0V A;  5JPF A;  3H60 A;  4OR9 A;  4I5N C;  4FBW A;  2WDD A;  1AUI A;  4M0V A;  4ZX2 A;  3AUZ A;  5EQV A;  3H67 A;  2IE3 C;  1XM7 A;  3E7B A;  2NPP C;  5B8I A;  1S70 A;  1T71 A;  1Z2W A;  4V0X A;  3T1I A;  2QFR A;  4ORB A;  3RQZ A;  4TUI A;  1SU1 A;  4TUG A;  2Z1A A;  3GVE A;  3QFO A;  4IL1 A;  4IYP C;  3PSO A;  2KKN A;  1S3N A;  1MF8 A;  3PSN A;  3H63 A;  2YVT A;  3EGH A;  4O24 A;  3H62 B;  3THO B;  1S8E A;  3C5W C;  4UT3 B;  4UWQ A;  3ZU0 A;  5HPE A;  5DNY A;  2BQ8 X;  4WWL A;  3RL3 A;  1OIE A;  2QJC A;  1HPU A;  1FJM A;  3DSD A;  4H1S A;  4LTY A;  5GTU A;  5C1V A;  3KBP A;  5F3W A;  3IVD A;  1G5B A;  2WDE A;  4V0W A;  4ORC A;  4LU9 A;  2Z72 A;  2XMO A;  4DHL A;  4MOV A;  1W24 A;  3ZTV A;  2JOG A;  4H2G A;  1OID A;  3FGA C;  4G9J A;  3EGG A;  2WDC A;  4KKZ A;  4DT2 A;  4O5G A;  2NYL C;  1WAR A;  4I5L C;  3H68 A;  1S3L A;  4F0Z A;  2WDF A;  3TGH A;  5JJT A;  1V73 A;  4UT3 A;  4YKE A;  3DW8 C;  1Z2X A; 
#chains in the Genus database with same CATH topology
 1S3M A;  1XZW A;  4KBP A;  4XPN A;  2Q8U A;  3C9F A;  2DXN A;  1UTE A;  2USH A;  4FBQ A;  5J28 A;  1TCO A;  2O8A A;  1T70 A;  4MOY A;  4H2B A;  5INB A;  4NZV A;  2R17 A;  1IT6 A;  1HP1 A;  3LL8 A;  2CV9 A;  1WAO 1;  2BCD A;  4ORA A;  2YEQ A;  2DXL A;  1QHW A;  3IVE A;  2HYO A;  3QG5 C;  2O8G A;  3QFK A;  4FCX A;  4Q7F A;  4UT2 A;  3THN A;  1M63 A;  4FBK A;  3QFN A;  2NXF A;  3H66 A;  4LAC C;  1KBP A;  4J6O A;  3DSC A;  2IE4 C;  3JYF A;  4O4K A;  2AHD A;  1U32 A;  3RL4 A;  3H64 A;  3K7V C;  3HVQ A;  4O43 A;  1USH A;  4H2I A;  2GJU A;  2A22 A;  2ZBM A;  4MP0 A;  1NNW A;  3ICF A;  2HYP A;  3E0J A;  3V4Y A;  2QFP A;  4HD0 A;  3RL5 A;  2IAE C;  4DSY A;  4B2O A;  5JPE A;  1HO5 A;  2HY1 A;  2NYM C;  1JK7 A;  1S95 A;  3AV0 A;  4JA7 A;  3IB8 A;  3CK2 A;  3IB7 A;  4ZVZ A;  5IOH A;  3K7W C;  4JA9 A;  1QFC A;  1II7 A;  3N5U A;  3QFM A;  2DFJ A;  4H2F A;  4H1Y P;  2P6B A;  3H61 A;  1UF3 A;  3E7A A;  3H69 A;  2BDX A;  3P71 C;  2Z06 A;  1OI8 A;  4V0V A;  5JPF A;  3H60 A;  4OR9 A;  4I5N C;  4FBW A;  2WDD A;  1AUI A;  4M0V A;  4ZX2 A;  3AUZ A;  5EQV A;  3H67 A;  2IE3 C;  1XM7 A;  3E7B A;  2NPP C;  5B8I A;  1S70 A;  1T71 A;  1Z2W A;  4V0X A;  3T1I A;  2QFR A;  4ORB A;  3RQZ A;  4TUI A;  1SU1 A;  4TUG A;  2Z1A A;  3GVE A;  3QFO A;  4IL1 A;  4IYP C;  3PSO A;  2KKN A;  1S3N A;  1MF8 A;  3PSN A;  3H63 A;  2YVT A;  3EGH A;  4O24 A;  3H62 B;  3THO B;  1S8E A;  3C5W C;  4UT3 B;  4UWQ A;  3ZU0 A;  5HPE A;  5DNY A;  2BQ8 X;  4WWL A;  3RL3 A;  1OIE A;  2QJC A;  1HPU A;  1FJM A;  3DSD A;  2ZOA A;  4H1S A;  3D03 A;  4LTY A;  5GTU A;  5C1V A;  3KBP A;  5F3W A;  3IVD A;  1G5B A;  2WDE A;  4V0W A;  4ORC A;  4LU9 A;  2Z72 A;  2XMO A;  4DHL A;  4MOV A;  1W24 A;  3ZTV A;  2JOG A;  4H2G A;  1OID A;  3FGA C;  4G9J A;  3EGG A;  2WDC A;  4KKZ A;  2ZO9 B;  4DT2 A;  4O5G A;  2NYL C;  1WAR A;  4I5L C;  3H68 A;  1S3L A;  4F0Z A;  2WDF A;  3TGH A;  5JJT A;  1V73 A;  4UT3 A;  4YKE A;  3FLO A;  3DW8 C;  1Z2X A; 
#chains in the Genus database with same CATH homology
 1S3M A;  1XZW A;  4KBP A;  4XPN A;  2Q8U A;  3C9F A;  2DXN A;  1UTE A;  2USH A;  4FBQ A;  5J28 A;  1TCO A;  2O8A A;  1T70 A;  4MOY A;  4H2B A;  5INB A;  4NZV A;  2R17 A;  1IT6 A;  1HP1 A;  3LL8 A;  2CV9 A;  1WAO 1;  2BCD A;  4ORA A;  2YEQ A;  2DXL A;  1QHW A;  3IVE A;  2HYO A;  3QG5 C;  2O8G A;  3QFK A;  4FCX A;  4Q7F A;  4UT2 A;  3THN A;  1M63 A;  4FBK A;  3QFN A;  2NXF A;  3H66 A;  4LAC C;  1KBP A;  4J6O A;  3DSC A;  2IE4 C;  3JYF A;  4O4K A;  2AHD A;  1U32 A;  3RL4 A;  3H64 A;  3K7V C;  3HVQ A;  4O43 A;  1USH A;  4H2I A;  2GJU A;  2A22 A;  2ZBM A;  4MP0 A;  1NNW A;  3ICF A;  2HYP A;  3E0J A;  3V4Y A;  2QFP A;  4HD0 A;  3RL5 A;  2IAE C;  4DSY A;  4B2O A;  5JPE A;  1HO5 A;  2HY1 A;  2NYM C;  1JK7 A;  1S95 A;  3AV0 A;  4JA7 A;  3IB8 A;  3CK2 A;  3IB7 A;  4ZVZ A;  5IOH A;  3K7W C;  4JA9 A;  1QFC A;  1II7 A;  3N5U A;  3QFM A;  2DFJ A;  4H2F A;  4H1Y P;  2P6B A;  3H61 A;  1UF3 A;  3E7A A;  3H69 A;  2BDX A;  3P71 C;  2Z06 A;  1OI8 A;  4V0V A;  5JPF A;  3H60 A;  4OR9 A;  4I5N C;  4FBW A;  2WDD A;  1AUI A;  4M0V A;  4ZX2 A;  3AUZ A;  5EQV A;  3H67 A;  2IE3 C;  1XM7 A;  3E7B A;  2NPP C;  5B8I A;  1S70 A;  1T71 A;  1Z2W A;  4V0X A;  3T1I A;  2QFR A;  4ORB A;  3RQZ A;  4TUI A;  1SU1 A;  4TUG A;  2Z1A A;  3GVE A;  3QFO A;  4IL1 A;  4IYP C;  3PSO A;  2KKN A;  1S3N A;  1MF8 A;  3PSN A;  3H63 A;  2YVT A;  3EGH A;  4O24 A;  3H62 B;  3THO B;  1S8E A;  3C5W C;  4UT3 B;  4UWQ A;  3ZU0 A;  5HPE A;  5DNY A;  2BQ8 X;  4WWL A;  3RL3 A;  1OIE A;  2QJC A;  1HPU A;  1FJM A;  3DSD A;  2ZOA A;  4H1S A;  3D03 A;  4LTY A;  5GTU A;  5C1V A;  3KBP A;  5F3W A;  3IVD A;  1G5B A;  2WDE A;  4V0W A;  4ORC A;  4LU9 A;  2Z72 A;  2XMO A;  4DHL A;  4MOV A;  1W24 A;  3ZTV A;  2JOG A;  4H2G A;  1OID A;  3FGA C;  4G9J A;  3EGG A;  2WDC A;  4KKZ A;  2ZO9 B;  4DT2 A;  4O5G A;  2NYL C;  1WAR A;  4I5L C;  3H68 A;  1S3L A;  4F0Z A;  2WDF A;  3TGH A;  5JJT A;  1V73 A;  4UT3 A;  4YKE A;  3FLO A;  3DW8 C;  1Z2X A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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