2QJZA

Structural basis of microtubule plus end tracking by xmap215, clip-170 and eb1
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
121
structure length
121
Chain Sequence
DNLSRHDMLAWINESLQLNLTKIEQLCSGAAYCQFMDMLFPGSIALKKVKFQAKLEHEYIQNFKILQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDGKDYDPVAARQGQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of Microtubule Plus End Tracking by XMAP215, CLIP-170, and EB1.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Microtubule-associated protein RP/EB family member 1
total genus 37
structure length 121
sequence length 121
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 2qjzA00
3JARM 1WIXA 2EE7A 3JALM 2R0OA 4EDMA 4Q57B 1RT8A 2WFNA 2VZIB 2VZCA 4Q58A 1UEGA 1AA2A 1BKRA 1WYOA 2JV9A 3F7PA 1WYQA 1P2XA 1PA7A 5J8EA 2EYIA 2VZGB 1UJOA 2EYNA 2K3SA 5A4BA 1VKAA 2E9KA 2D86A 5A36A 3KMWB 2D87A 1WYMA 3KMUB 1MB8A 2WA7A 2D89A 3HORA 4TXIA 3I6XA 3JAKM 2RR8A 5A38A 2L3GA 1TJTA 2VZDA 5BVRA 2WA5A 1WYRA 1WKUA 1WYPA 1WYLA 2D85A 1DXXA 4B7LA 3HOPA 2D88A 3FERA 2K2RA 2QJZA 2YRNA 3REPB 1H67A 4TXKA 2WA6A 1WJOA 1AOAA 4EDLA 1P5SA 3KY9A 1SH6A 3HOCA 2R8UA 5A37A 1PXYA 4Q59A 2DK9A 2QJXA 1SH5A 1V5KA 1QAGA 3CO1A 4EDNA 1BHDA 1WYNA 5L0OA
chains in the Genus database with same CATH superfamily
3JARM 1WIXA 2EE7A 3JALM 2R0OA 4LVRA 4EDMA 4Q57B 1RT8A 2WFNA 2VZIB 2VZCA 4Q58A 1UEGA 1AA2A 1BKRA 5FMTA 1WYOA 2JV9A 5FMUA 3F7PA 1WYQA 1P2XA 1PA7A 5J8EA 2EYIA 2VZGB 1UJOA 2EYNA 2K3SA 4DDPA 5A4BA 1VKAA 2E9KA 2D86A 5A36A 3KMWB 1EUVA 2D87A 1WYMA 3KMUB 1MB8A 2WA7A 2D89A 3HORA 4TXIA 3I6XA 3JAKM 2RR8A 5A38A 2L3GA 1TJTA 2VZDA 5BVRA 2WA5A 1WYRA 1WKUA 1WYPA 1WYLA 2D85A 3VP7A 1DXXA 4LVPA 4B7LA 3HOPA 2D88A 2HL9A 3FERA 2K2RA 2QJZA 2YRNA 3REPB 1H67A 4TXKA 2WA6A 1WJOA 1AOAA 4EDLA 2HKPA 2IGPA 1P5SA 3KY9A 1SH6A 3HOCA 2R8UA 5A37A 2EQOA 1PXYA 4Q59A 2WDTA 2DK9A 2HL8A 2QJXA 1SH5A 1V5KA 3EAYA 1QAGA 3CO1A 2VE7C 4EDNA 1BHDA 1WYNA 2VE7A 2WE6A 5L0OA
chains in the Genus database with same CATH topology
3JARM 1WIXA 2EE7A 3JALM 2R0OA 4EDMA 4Q57B 1RT8A 2WFNA 2VZIB 2VZCA 4Q58A 1UEGA 1AA2A 1BKRA 1WYOA 2JV9A 3F7PA 1WYQA 1P2XA 1PA7A 5J8EA 2EYIA 2VZGB 1UJOA 2EYNA 2K3SA 5A4BA 1VKAA 2E9KA 2D86A 5A36A 3KMWB 2D87A 1WYMA 3KMUB 1MB8A 2WA7A 2D89A 3HORA 4TXIA 3I6XA 3JAKM 2RR8A 5A38A 2L3GA 1TJTA 2VZDA 5BVRA 2WA5A 1WYRA 1WKUA 1WYPA 1WYLA 2D85A 1DXXA 4B7LA 3HOPA 2D88A 3FERA 2K2RA 2QJZA 2YRNA 3REPB 1H67A 4TXKA 2WA6A 1WJOA 1AOAA 4EDLA 1P5SA 3KY9A 1SH6A 3HOCA 2R8UA 5A37A 1PXYA 4Q59A 2DK9A 2QJXA 1SH5A 1V5KA 1QAGA 3CO1A 4EDNA 1BHDA 1WYNA 5L0OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3JAR M;  1WIX A;  2EE7 A;  3JAL M;  2R0O A;  4EDM A;  4Q57 B;  1RT8 A;  2WFN A;  2VZI B;  2VZC A;  4Q58 A;  1UEG A;  1AA2 A;  1BKR A;  1WYO A;  2JV9 A;  3F7P A;  1WYQ A;  1P2X A;  1PA7 A;  5J8E A;  2EYI A;  2VZG B;  1UJO A;  2EYN A;  2K3S A;  5A4B A;  1VKA A;  2E9K A;  2D86 A;  5A36 A;  3KMW B;  2D87 A;  1WYM A;  3KMU B;  1MB8 A;  2WA7 A;  2D89 A;  3HOR A;  4TXI A;  3I6X A;  3JAK M;  2RR8 A;  5A38 A;  2L3G A;  1TJT A;  2VZD A;  5BVR A;  2WA5 A;  1WYR A;  1WKU A;  1WYP A;  1WYL A;  2D85 A;  1DXX A;  4B7L A;  3HOP A;  2D88 A;  3FER A;  2K2R A;  2QJZ A;  2YRN A;  3REP B;  1H67 A;  4TXK A;  2WA6 A;  1WJO A;  1AOA A;  4EDL A;  1P5S A;  3KY9 A;  1SH6 A;  3HOC A;  2R8U A;  5A37 A;  1PXY A;  4Q59 A;  2DK9 A;  2QJX A;  1SH5 A;  1V5K A;  1QAG A;  3CO1 A;  4EDN A;  1BHD A;  1WYN A;  5L0O A; 
#chains in the Genus database with same CATH topology
 3JAR M;  1WIX A;  2EE7 A;  3JAL M;  2R0O A;  4LVR A;  4EDM A;  4Q57 B;  1RT8 A;  2WFN A;  2VZI B;  2VZC A;  4Q58 A;  1UEG A;  1AA2 A;  1BKR A;  5FMT A;  1WYO A;  2JV9 A;  5FMU A;  3F7P A;  1WYQ A;  1P2X A;  1PA7 A;  5J8E A;  2EYI A;  2VZG B;  1UJO A;  2EYN A;  2K3S A;  4DDP A;  5A4B A;  1VKA A;  2E9K A;  2D86 A;  5A36 A;  3KMW B;  1EUV A;  2D87 A;  1WYM A;  3KMU B;  1MB8 A;  2WA7 A;  2D89 A;  3HOR A;  4TXI A;  3I6X A;  3JAK M;  2RR8 A;  5A38 A;  2L3G A;  1TJT A;  2VZD A;  5BVR A;  2WA5 A;  1WYR A;  1WKU A;  1WYP A;  1WYL A;  2D85 A;  3VP7 A;  1DXX A;  4LVP A;  4B7L A;  3HOP A;  2D88 A;  2HL9 A;  3FER A;  2K2R A;  2QJZ A;  2YRN A;  3REP B;  1H67 A;  4TXK A;  2WA6 A;  1WJO A;  1AOA A;  4EDL A;  2HKP A;  2IGP A;  1P5S A;  3KY9 A;  1SH6 A;  3HOC A;  2R8U A;  5A37 A;  2EQO A;  1PXY A;  4Q59 A;  2WDT A;  2DK9 A;  2HL8 A;  2QJX A;  1SH5 A;  1V5K A;  3EAY A;  1QAG A;  3CO1 A;  2VE7 C;  4EDN A;  1BHD A;  1WYN A;  2VE7 A;  2WE6 A;  5L0O A; 
#chains in the Genus database with same CATH homology
 3JAR M;  1WIX A;  2EE7 A;  3JAL M;  2R0O A;  4EDM A;  4Q57 B;  1RT8 A;  2WFN A;  2VZI B;  2VZC A;  4Q58 A;  1UEG A;  1AA2 A;  1BKR A;  1WYO A;  2JV9 A;  3F7P A;  1WYQ A;  1P2X A;  1PA7 A;  5J8E A;  2EYI A;  2VZG B;  1UJO A;  2EYN A;  2K3S A;  5A4B A;  1VKA A;  2E9K A;  2D86 A;  5A36 A;  3KMW B;  2D87 A;  1WYM A;  3KMU B;  1MB8 A;  2WA7 A;  2D89 A;  3HOR A;  4TXI A;  3I6X A;  3JAK M;  2RR8 A;  5A38 A;  2L3G A;  1TJT A;  2VZD A;  5BVR A;  2WA5 A;  1WYR A;  1WKU A;  1WYP A;  1WYL A;  2D85 A;  1DXX A;  4B7L A;  3HOP A;  2D88 A;  3FER A;  2K2R A;  2QJZ A;  2YRN A;  3REP B;  1H67 A;  4TXK A;  2WA6 A;  1WJO A;  1AOA A;  4EDL A;  1P5S A;  3KY9 A;  1SH6 A;  3HOC A;  2R8U A;  5A37 A;  1PXY A;  4Q59 A;  2DK9 A;  2QJX A;  1SH5 A;  1V5K A;  1QAG A;  3CO1 A;  4EDN A;  1BHD A;  1WYN A;  5L0O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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