2QM6A

Crystal structure of helicobacter pylori gamma-glutamyltranspeptidase in complex with glutamate
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
342
structure length
342
Chain Sequence
IKNTKVGLALSSHPLASEIGQKVLEEGGNAIDAAVAIGFALAVVHPAAGNIGGGGFAVIHLANGENVALDFREKAPLKATKNMFLDKQGNVVPKLSEDGYLAAGVPGTVAGMEAMLKKYGTKKLSQLIDPAIKLAENGYAISQRQAETLKEARERFLKYSSSKKYFFKKGHLDYQEGDLFVQKDLAKTLNQIKTLGAKGFYQGQVAELIEKDMKKNGGIITKEDLASYNVKWRKPVVGSYRGYKIISMSPPSSGGTHLIQILNVMENADLSALGYGASKNIHIAAEAMRQAYADRSVYMGDADFVSVPVDKLINKAYAKKIFDTIQPDTVTPSSQIKPGMGQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Gamma-glutamyltranspeptidase
publication title Characterization of Helicobacter pylori gamma-glutamyltranspeptidase reveals the molecular basis for substrate specificity and a critical role for the tyrosine 433-containing loop in catalysis.
pubmed doi rcsb
source organism Helicobacter pylori
molecule tags Transferase
total genus 108
structure length 342
sequence length 342
chains with identical sequence C
ec nomenclature ec 2.3.2.2: Gamma-glutamyltransferase.
pdb deposition date 2007-07-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.130 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2qm6A02
2QM6A 2DBWA 2DG5A 4OTUA 4GDXA 2DBUA 2Z8IA 2E0YA 4ZC6A 4OTTA 5B5TA 5BPKA 2NQOA 2E0XA 2V36A 4ZCGA 4ZBKA 4GG2A 3FNMA 2DBXA 3A75A 4Z9OA 2Z8KA 3WHRA 3WHQA 2Z8JA 2QMCA 3WHSA
chains in the Genus database with same CATH superfamily
2EFHA 4N0UD 2DG5A 4EMXA 3M99C 2XSIA 3JQZA 2BXLA 3GQUA 4N3ZA 5DBYA 5IIXA 4K2CA 2LXSA 2Z8IA 2VUEA 3FWCC 3LU6A 4JK4A 3A73A 3JRYA 4OTTA 4OT2A 5GHKA 5B5TA 1UORA 2ROHA 3B9LA 3KIKA 4HGMB 2BXGA 1E7HA 4WA6B 3BPJA 1LOTA 4E99A 1FOUA 4LUHA 3VQIA 1N5UA 2XMOA 4LA0A 3G9KD 4Z9OA 3TDLA 5GINA 3SIVB 1E7IA 1LNSA 4BKEA 1E7AA 4G03A 4IW2A 3H37A 2GUTA 1HK3A 3WHQA 2BX8A 2JUHA 2VDBA 1E78A 4L9QA 4ZBQA 4TQ0A 3B9MA 1VZSA 2BXMA 2BXQA 1O9XA 4J2VA 1NT2B 1KDXA 4G04A 3WHSA 4S1YA 1GNIA 1J7EA 2I2ZA 4G01A 1KXPD 5IFOA 1JNBA 5ID7A 2BXNA 1HA2A 3LU8A 1BM0A 3H3AA 2EFCA 4FJCB 4ZUXV 2XW1A 2LOQA 1H5WA 2V36A 4L9KA 5HOZA 2YDFA 4F5TA 2BXAA 5GIPA 1KW2A 3KJLA 4IW1A 2DBXA 3FNMA 3SQJA 3V08A 4D7XA 2BXDA 3NVKA 4GDLB 3MHSB 2AJEA 5DQFA 1TF0A 1J78A 3SIUB 2KWFA 3WHRA 4W4UB 4Z69A 2LXTA 2XW0A 2VUFA 2BXHA 1HK2A 5ID9A 2XVQA 2XVWA 3GA9L 2QM6A 5IJ5A 2DBWA 2BXIA 2BXPA 2BXKA 2DBUA 4BY9C 1MA9A 3NMUA 3MHHB 2XVVA 4ZC6A 5FUOA 4GDKB 3V03A 2QHBA 2CKXA 4HGKA 1MIWA 4ZCGA 4ZBKA 1AO6A 1MUHA 1E7EA 4TQ1A 1IJGA 2BXFA 1MIVA 1SB0A 3GQXA 4PO0A 2BXCA 2LQHA 2NNWA 5IJEA 5IJFA 4LB9A 2BXOA 2Z8JA 1TXUA 4DM0A 1E7GA 2DYOA 3NVMA 5GIOA 4I9OA 3PLAA 2LQIA 3ECPA 1E7CA 1HK1A 4N0FD 2BXBA 5BPKA 2AGHB 2EFEA 2KBZA 4L8UA 4K71A 4OTUA 2DYMA 4GDXA 3UIVA 1HK5A 3W1SA 4C31B 4LUFA 2E0YA 4MBEC 3NVIA 4FK5B 1BKEA 4LB2A 4NAWB 4F5SA 2NQOA 4DHXB 2E0XA 2XVUA 2OZBB 4GG2A 5IIHA 1E7BA 2OT3A 1HK4A 3A75A 3CX9A 1MIYA 3V09A 4M70B 2BXEA 1BJ5A 2I30A 2Z8KA 3LU7A 1MUSA 1H9ZA 3FWBC 3ICXA 4FIPB 1GNJA 4OR0A 1VFIA 4F5UA 1MM8A 2K0NA 4F5VA 1E7FA 4ZBRA 2QMCA 2EFDA 5D7GA 5IIUA
chains in the Genus database with same CATH topology
2EFHA 4N0UD 2DG5A 4EMXA 3M99C 2XSIA 3JQZA 2BXLA 3GQUA 4N3ZA 5DBYA 5IIXA 4K2CA 2Z8IA 2VUEA 3FWCC 3LU6A 4JK4A 3A73A 3JRYA 4OTTA 4OT2A 5GHKA 5B5TA 1UORA 2ROHA 3B9LA 3KIKA 4HGMB 2BXGA 1E7HA 4WA6B 1LOTA 4E99A 1FOUA 4LUHA 3VQIA 1N5UA 2XMOA 4LA0A 3G9KD 4Z9OA 3TDLA 5GINA 3SIVB 1E7IA 1LNSA 4BKEA 1E7AA 4G03A 4IW2A 3H37A 3WHQA 1HK3A 2BX8A 2JUHA 2VDBA 1E78A 4L9QA 4ZBQA 4TQ0A 3B9MA 1VZSA 2BXMA 2BXQA 1O9XA 4J2VA 1NT2B 4G04A 3WHSA 4S1YA 1GNIA 1J7EA 2I2ZA 4G01A 1KXPD 5IFOA 1JNBA 5ID7A 2BXNA 1HA2A 3LU8A 1BM0A 3H3AA 2EFCA 4FJCB 4ZUXV 2XW1A 2LOQA 1H5WA 2V36A 4L9KA 5HOZA 2YDFA 4F5TA 2BXAA 5GIPA 1KW2A 3KJLA 4IW1A 2DBXA 3FNMA 3SQJA 3V08A 3NVKA 2BXDA 4GDLB 3MHSB 2AJEA 5DQFA 1TF0A 1J78A 3SIUB 3WHRA 4W4UB 4Z69A 2XW0A 2VUFA 2BXHA 1HK2A 5ID9A 2XVQA 2XVWA 3GA9L 2QM6A 5IJ5A 2DBWA 2BXIA 2BXPA 2BXKA 2DBUA 4BY9C 1MA9A 3NMUA 3MHHB 2XVVA 4ZC6A 5FUOA 4GDKB 3V03A 2QHBA 2CKXA 4HGKA 1MIWA 4ZCGA 4ZBKA 1AO6A 1E7EA 4TQ1A 1IJGA 2BXFA 1MIVA 3GQXA 4PO0A 2BXCA 2NNWA 5IJEA 5IJFA 4LB9A 2BXOA 2Z8JA 1TXUA 1E7GA 2DYOA 3NVMA 5GIOA 3PLAA 1E7CA 1HK1A 4N0FD 2BXBA 5BPKA 2EFEA 4L8UA 2KBZA 4K71A 4OTUA 2DYMA 4GDXA 3UIVA 1HK5A 3W1SA 4C31B 4LUFA 2E0YA 4MBEC 3NVIA 4FK5B 1BKEA 4LB2A 4NAWB 4F5SA 2NQOA 4DHXB 2E0XA 2XVUA 2OZBB 4GG2A 5IIHA 1E7BA 2OT3A 1HK4A 3A75A 3CX9A 1MIYA 3V09A 4M70B 2BXEA 1BJ5A 2I30A 2Z8KA 3LU7A 1H9ZA 3FWBC 3ICXA 4FIPB 1GNJA 4OR0A 1VFIA 4F5UA 4F5VA 1E7FA 4ZBRA 2QMCA 2EFDA 5D7GA 5IIUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QM6 A;  2DBW A;  2DG5 A;  4OTU A;  4GDX A;  2DBU A;  2Z8I A;  2E0Y A;  4ZC6 A;  4OTT A;  5B5T A;  5BPK A;  2NQO A;  2E0X A;  2V36 A;  4ZCG A;  4ZBK A;  4GG2 A;  3FNM A;  2DBX A;  3A75 A;  4Z9O A;  2Z8K A;  3WHR A;  3WHQ A;  2Z8J A;  2QMC A;  3WHS A; 
#chains in the Genus database with same CATH topology
 2EFH A;  4N0U D;  2DG5 A;  4EMX A;  3M99 C;  2XSI A;  3JQZ A;  2BXL A;  3GQU A;  4N3Z A;  5DBY A;  5IIX A;  4K2C A;  2LXS A;  2Z8I A;  2VUE A;  3FWC C;  3LU6 A;  4JK4 A;  3A73 A;  3JRY A;  4OTT A;  4OT2 A;  5GHK A;  5B5T A;  1UOR A;  2ROH A;  3B9L A;  3KIK A;  4HGM B;  2BXG A;  1E7H A;  4WA6 B;  3BPJ A;  1LOT A;  4E99 A;  1FOU A;  4LUH A;  3VQI A;  1N5U A;  2XMO A;  4LA0 A;  3G9K D;  4Z9O A;  3TDL A;  5GIN A;  3SIV B;  1E7I A;  1LNS A;  4BKE A;  1E7A A;  4G03 A;  4IW2 A;  3H37 A;  2GUT A;  1HK3 A;  3WHQ A;  2BX8 A;  2JUH A;  2VDB A;  1E78 A;  4L9Q A;  4ZBQ A;  4TQ0 A;  3B9M A;  1VZS A;  2BXM A;  2BXQ A;  1O9X A;  4J2V A;  1NT2 B;  1KDX A;  4G04 A;  3WHS A;  4S1Y A;  1GNI A;  1J7E A;  2I2Z A;  4G01 A;  1KXP D;  5IFO A;  1JNB A;  5ID7 A;  2BXN A;  1HA2 A;  3LU8 A;  1BM0 A;  3H3A A;  2EFC A;  4FJC B;  4ZUX V;  2XW1 A;  2LOQ A;  1H5W A;  2V36 A;  4L9K A;  5HOZ A;  2YDF A;  4F5T A;  2BXA A;  5GIP A;  1KW2 A;  3KJL A;  4IW1 A;  2DBX A;  3FNM A;  3SQJ A;  3V08 A;  4D7X A;  2BXD A;  3NVK A;  4GDL B;  3MHS B;  2AJE A;  5DQF A;  1TF0 A;  1J78 A;  3SIU B;  2KWF A;  3WHR A;  4W4U B;  4Z69 A;  2LXT A;  2XW0 A;  2VUF A;  2BXH A;  1HK2 A;  5ID9 A;  2XVQ A;  2XVW A;  3GA9 L;  2QM6 A;  5IJ5 A;  2DBW A;  2BXI A;  2BXP A;  2BXK A;  2DBU A;  4BY9 C;  1MA9 A;  3NMU A;  3MHH B;  2XVV A;  4ZC6 A;  5FUO A;  4GDK B;  3V03 A;  2QHB A;  2CKX A;  4HGK A;  1MIW A;  4ZCG A;  4ZBK A;  1AO6 A;  1MUH A;  1E7E A;  4TQ1 A;  1IJG A;  2BXF A;  1MIV A;  1SB0 A;  3GQX A;  4PO0 A;  2BXC A;  2LQH A;  2NNW A;  5IJE A;  5IJF A;  4LB9 A;  2BXO A;  2Z8J A;  1TXU A;  4DM0 A;  1E7G A;  2DYO A;  3NVM A;  5GIO A;  4I9O A;  3PLA A;  2LQI A;  3ECP A;  1E7C A;  1HK1 A;  4N0F D;  2BXB A;  5BPK A;  2AGH B;  2EFE A;  2KBZ A;  4L8U A;  4K71 A;  4OTU A;  2DYM A;  4GDX A;  3UIV A;  1HK5 A;  3W1S A;  4C31 B;  4LUF A;  2E0Y A;  4MBE C;  3NVI A;  4FK5 B;  1BKE A;  4LB2 A;  4NAW B;  4F5S A;  2NQO A;  4DHX B;  2E0X A;  2XVU A;  2OZB B;  4GG2 A;  5IIH A;  1E7B A;  2OT3 A;  1HK4 A;  3A75 A;  3CX9 A;  1MIY A;  3V09 A;  4M70 B;  2BXE A;  1BJ5 A;  2I30 A;  2Z8K A;  3LU7 A;  1MUS A;  1H9Z A;  3FWB C;  3ICX A;  4FIP B;  1GNJ A;  4OR0 A;  1VFI A;  4F5U A;  1MM8 A;  2K0N A;  4F5V A;  1E7F A;  4ZBR A;  2QMC A;  2EFD A;  5D7G A;  5IIU A; 
#chains in the Genus database with same CATH homology
 2EFH A;  4N0U D;  2DG5 A;  4EMX A;  3M99 C;  2XSI A;  3JQZ A;  2BXL A;  3GQU A;  4N3Z A;  5DBY A;  5IIX A;  4K2C A;  2Z8I A;  2VUE A;  3FWC C;  3LU6 A;  4JK4 A;  3A73 A;  3JRY A;  4OTT A;  4OT2 A;  5GHK A;  5B5T A;  1UOR A;  2ROH A;  3B9L A;  3KIK A;  4HGM B;  2BXG A;  1E7H A;  4WA6 B;  1LOT A;  4E99 A;  1FOU A;  4LUH A;  3VQI A;  1N5U A;  2XMO A;  4LA0 A;  3G9K D;  4Z9O A;  3TDL A;  5GIN A;  3SIV B;  1E7I A;  1LNS A;  4BKE A;  1E7A A;  4G03 A;  4IW2 A;  3H37 A;  3WHQ A;  1HK3 A;  2BX8 A;  2JUH A;  2VDB A;  1E78 A;  4L9Q A;  4ZBQ A;  4TQ0 A;  3B9M A;  1VZS A;  2BXM A;  2BXQ A;  1O9X A;  4J2V A;  1NT2 B;  4G04 A;  3WHS A;  4S1Y A;  1GNI A;  1J7E A;  2I2Z A;  4G01 A;  1KXP D;  5IFO A;  1JNB A;  5ID7 A;  2BXN A;  1HA2 A;  3LU8 A;  1BM0 A;  3H3A A;  2EFC A;  4FJC B;  4ZUX V;  2XW1 A;  2LOQ A;  1H5W A;  2V36 A;  4L9K A;  5HOZ A;  2YDF A;  4F5T A;  2BXA A;  5GIP A;  1KW2 A;  3KJL A;  4IW1 A;  2DBX A;  3FNM A;  3SQJ A;  3V08 A;  3NVK A;  2BXD A;  4GDL B;  3MHS B;  2AJE A;  5DQF A;  1TF0 A;  1J78 A;  3SIU B;  3WHR A;  4W4U B;  4Z69 A;  2XW0 A;  2VUF A;  2BXH A;  1HK2 A;  5ID9 A;  2XVQ A;  2XVW A;  3GA9 L;  2QM6 A;  5IJ5 A;  2DBW A;  2BXI A;  2BXP A;  2BXK A;  2DBU A;  4BY9 C;  1MA9 A;  3NMU A;  3MHH B;  2XVV A;  4ZC6 A;  5FUO A;  4GDK B;  3V03 A;  2QHB A;  2CKX A;  4HGK A;  1MIW A;  4ZCG A;  4ZBK A;  1AO6 A;  1E7E A;  4TQ1 A;  1IJG A;  2BXF A;  1MIV A;  3GQX A;  4PO0 A;  2BXC A;  2NNW A;  5IJE A;  5IJF A;  4LB9 A;  2BXO A;  2Z8J A;  1TXU A;  1E7G A;  2DYO A;  3NVM A;  5GIO A;  3PLA A;  1E7C A;  1HK1 A;  4N0F D;  2BXB A;  5BPK A;  2EFE A;  4L8U A;  2KBZ A;  4K71 A;  4OTU A;  2DYM A;  4GDX A;  3UIV A;  1HK5 A;  3W1S A;  4C31 B;  4LUF A;  2E0Y A;  4MBE C;  3NVI A;  4FK5 B;  1BKE A;  4LB2 A;  4NAW B;  4F5S A;  2NQO A;  4DHX B;  2E0X A;  2XVU A;  2OZB B;  4GG2 A;  5IIH A;  1E7B A;  2OT3 A;  1HK4 A;  3A75 A;  3CX9 A;  1MIY A;  3V09 A;  4M70 B;  2BXE A;  1BJ5 A;  2I30 A;  2Z8K A;  3LU7 A;  1H9Z A;  3FWB C;  3ICX A;  4FIP B;  1GNJ A;  4OR0 A;  1VFI A;  4F5U A;  4F5V A;  1E7F A;  4ZBR A;  2QMC A;  2EFD A;  5D7G A;  5IIU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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