2QPWA

Methyltransferase domain of human pr domain-containing protein 2
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
147
structure length
147
Chain Sequence
NQNTTEPVAATETLAEVPEHVLRGLPEEVRLFPSAVDKTRIGVWATKPILKGKKFGPFVGDKKKRSQVKNNVYMWEVYYPNLGWMCIDATDPEKGNWLRYVNWACSGEEQNLFPLEINRAIYYKTLKPIAPGEELLVWYNGEDNPEI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural biology of human H3K9 methyltransferases
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords PR domain zinc finger protein 2
total genus 31
structure length 147
sequence length 147
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2007-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 2qpwA01
3CBPA 4QEPA 4I51A 5ARGA 5EX3A 4IJDA 2W5ZA 4YNDA 5EX0A 5JINA 4H12A 3VV0A 2JV0A 4QEOA 3F9YA 2G46A 3KMAA 5CPRB 4YNPA 4E47A 1ZKKA 3KMTA 5JJ0A 3RQ4A 3CBMA 5KJKA 1N3JA 3S7DA 4RZ0A 5F6KC 3DALA 1MVHA 3OS5A 3M54A 5F5EA 4O6FA 3SW9A 1MUFA 1ML9A 4J7FA 3OXGA 1O9SA 4YNMA 3S8PA 5KJNA 3S7JA 1H3IA 3QWPA 4YPUA 5ARFA 4NVQA 1MVXA 3OXFA 5F6LA 5CCLA 2O8JA 3DB5A 1MT6A 3M53A 3QWWA 4JDSA 2W5YA 5JHNA 3SWCA 3N71A 4J8OA 3BO5A 4LDGA 5CCMA 3TG5A 4NJ5A 4JLGA 3K5KA 3HNAA 3IHXA 2BQZA 2IGQA 3MO0A 5LSXA 5KJLA 4IJ8A 3M57A 3MO5A 2RFIA 3M58A 5F59A 4O30A 5T0KA 3CBOA 5JIYA 3RIBA 5T0MA 3F9ZA 5TH7A 3RJWA 4J7IA 3QWVA 5AYFA 3OXLA 4AU7A 4Z4PA 3OPEA 5HI7A 4FMUA 4C1QA 4MI5A 5KJMA 3F9XA 5EG2A 3RU0A 3OOIA 3M59A 5TEGA 3F9WA 4QENA 4YPEA 3M55A 3EP0A 3TG4A 5HQ8A 3S7BA 3M5AA 3FPDA 2F69A 3VUZA 1N6CA 4BUPA 4WUYA 5T5GA 4J83A 3S7FA 2R3AA 4MI0A 3MO2A 5LSZA 1XQHA 1PEGA 2QPWA 3PDNA 5TTFA 4YPAA 3RAYA 3KMJA 3MEKA 3M56A 1N6AA
chains in the Genus database with same CATH superfamily
3CBPA 4QEPA 4I51A 5ARGA 5EX3A 4IJDA 2W5ZA 4YNDA 5EX0A 5JINA 4H12A 3VV0A 2JV0A 4QEOA 3F9YA 2G46A 3KMAA 5CPRB 4YNPA 4E47A 1ZKKA 3KMTA 5JJ0A 3RQ4A 3CBMA 5KJKA 1N3JA 3S7DA 4RZ0A 5F6KC 3DALA 1MVHA 3OS5A 3M54A 5F5EA 4O6FA 3SW9A 1MUFA 1ML9A 4J7FA 3OXGA 1O9SA 4YNMA 3S8PA 5KJNA 3S7JA 1H3IA 3QWPA 4YPUA 5ARFA 4NVQA 1MVXA 3OXFA 5F6LA 5CCLA 2O8JA 3DB5A 1MT6A 3M53A 3QWWA 4JDSA 2W5YA 5JHNA 3SWCA 3N71A 4J8OA 3BO5A 4LDGA 5CCMA 3TG5A 4NJ5A 4JLGA 3K5KA 3HNAA 3IHXA 2BQZA 2IGQA 3MO0A 5LSXA 5KJLA 4IJ8A 3M57A 3MO5A 2RFIA 3M58A 5F59A 4O30A 5T0KA 3CBOA 5JIYA 3RIBA 5T0MA 3F9ZA 5TH7A 3RJWA 4J7IA 3QWVA 5AYFA 3OXLA 4AU7A 4Z4PA 3OPEA 5HI7A 4FMUA 4C1QA 4MI5A 5KJMA 3F9XA 5EG2A 3RU0A 3OOIA 3M59A 5TEGA 3F9WA 4QENA 4YPEA 3M55A 3EP0A 3TG4A 5HQ8A 3S7BA 3M5AA 3FPDA 2F69A 3VUZA 1N6CA 4BUPA 4WUYA 5T5GA 4J83A 3S7FA 2R3AA 4MI0A 3MO2A 5LSZA 1XQHA 1PEGA 2QPWA 3PDNA 5TTFA 4YPAA 3RAYA 3KMJA 3MEKA 3M56A 1N6AA
chains in the Genus database with same CATH topology
3CBPA 4QEPA 4I51A 5ARGA 5EX3A 4IJDA 2W5ZA 4YNDA 5EX0A 5JINA 4H12A 3VV0A 2JV0A 4QEOA 3F9YA 2G46A 3KMAA 5CPRB 4YNPA 4E47A 1ZKKA 3KMTA 5JJ0A 3RQ4A 3CBMA 5KJKA 1N3JA 3S7DA 4RZ0A 5F6KC 3DALA 1MVHA 3OS5A 3M54A 5F5EA 4O6FA 3SW9A 1MUFA 1ML9A 4J7FA 3OXGA 1O9SA 4YNMA 3S8PA 5KJNA 3S7JA 1H3IA 3QWPA 4YPUA 5ARFA 4NVQA 1MVXA 3OXFA 5F6LA 5CCLA 2O8JA 3DB5A 1MT6A 3M53A 3QWWA 4JDSA 2W5YA 5JHNA 3SWCA 3N71A 4J8OA 3BO5A 4LDGA 5CCMA 3TG5A 4NJ5A 4JLGA 3K5KA 3HNAA 3IHXA 2BQZA 2IGQA 3MO0A 5LSXA 5KJLA 4IJ8A 3M57A 3MO5A 2RFIA 3M58A 5F59A 4O30A 5T0KA 3CBOA 5JIYA 3RIBA 5T0MA 3F9ZA 5TH7A 3RJWA 4J7IA 3QWVA 5AYFA 3OXLA 4AU7A 4Z4PA 3OPEA 5HI7A 4FMUA 4C1QA 4MI5A 5KJMA 3F9XA 5EG2A 3RU0A 3OOIA 3M59A 5TEGA 3F9WA 4QENA 4YPEA 3M55A 3EP0A 3TG4A 5HQ8A 3S7BA 3M5AA 3FPDA 2F69A 3VUZA 1N6CA 4BUPA 4WUYA 5T5GA 4J83A 3S7FA 2R3AA 4MI0A 3MO2A 5LSZA 1XQHA 1PEGA 2QPWA 3PDNA 5TTFA 4YPAA 3RAYA 3KMJA 3MEKA 3M56A 1N6AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CBP A;  4QEP A;  4I51 A;  5ARG A;  5EX3 A;  4IJD A;  2W5Z A;  4YND A;  5EX0 A;  5JIN A;  4H12 A;  3VV0 A;  2JV0 A;  4QEO A;  3F9Y A;  2G46 A;  3KMA A;  5CPR B;  4YNP A;  4E47 A;  1ZKK A;  3KMT A;  5JJ0 A;  3RQ4 A;  3CBM A;  5KJK A;  1N3J A;  3S7D A;  4RZ0 A;  5F6K C;  3DAL A;  1MVH A;  3OS5 A;  3M54 A;  5F5E A;  4O6F A;  3SW9 A;  1MUF A;  1ML9 A;  4J7F A;  3OXG A;  1O9S A;  4YNM A;  3S8P A;  5KJN A;  3S7J A;  1H3I A;  3QWP A;  4YPU A;  5ARF A;  4NVQ A;  1MVX A;  3OXF A;  5F6L A;  5CCL A;  2O8J A;  3DB5 A;  1MT6 A;  3M53 A;  3QWW A;  4JDS A;  2W5Y A;  5JHN A;  3SWC A;  3N71 A;  4J8O A;  3BO5 A;  4LDG A;  5CCM A;  3TG5 A;  4NJ5 A;  4JLG A;  3K5K A;  3HNA A;  3IHX A;  2BQZ A;  2IGQ A;  3MO0 A;  5LSX A;  5KJL A;  4IJ8 A;  3M57 A;  3MO5 A;  2RFI A;  3M58 A;  5F59 A;  4O30 A;  5T0K A;  3CBO A;  5JIY A;  3RIB A;  5T0M A;  3F9Z A;  5TH7 A;  3RJW A;  4J7I A;  3QWV A;  5AYF A;  3OXL A;  4AU7 A;  4Z4P A;  3OPE A;  5HI7 A;  4FMU A;  4C1Q A;  4MI5 A;  5KJM A;  3F9X A;  5EG2 A;  3RU0 A;  3OOI A;  3M59 A;  5TEG A;  3F9W A;  4QEN A;  4YPE A;  3M55 A;  3EP0 A;  3TG4 A;  5HQ8 A;  3S7B A;  3M5A A;  3FPD A;  2F69 A;  3VUZ A;  1N6C A;  4BUP A;  4WUY A;  5T5G A;  4J83 A;  3S7F A;  2R3A A;  4MI0 A;  3MO2 A;  5LSZ A;  1XQH A;  1PEG A;  2QPW A;  3PDN A;  5TTF A;  4YPA A;  3RAY A;  3KMJ A;  3MEK A;  3M56 A;  1N6A A; 
#chains in the Genus database with same CATH topology
 3CBP A;  4QEP A;  4I51 A;  5ARG A;  5EX3 A;  4IJD A;  2W5Z A;  4YND A;  5EX0 A;  5JIN A;  4H12 A;  3VV0 A;  2JV0 A;  4QEO A;  3F9Y A;  2G46 A;  3KMA A;  5CPR B;  4YNP A;  4E47 A;  1ZKK A;  3KMT A;  5JJ0 A;  3RQ4 A;  3CBM A;  5KJK A;  1N3J A;  3S7D A;  4RZ0 A;  5F6K C;  3DAL A;  1MVH A;  3OS5 A;  3M54 A;  5F5E A;  4O6F A;  3SW9 A;  1MUF A;  1ML9 A;  4J7F A;  3OXG A;  1O9S A;  4YNM A;  3S8P A;  5KJN A;  3S7J A;  1H3I A;  3QWP A;  4YPU A;  5ARF A;  4NVQ A;  1MVX A;  3OXF A;  5F6L A;  5CCL A;  2O8J A;  3DB5 A;  1MT6 A;  3M53 A;  3QWW A;  4JDS A;  2W5Y A;  5JHN A;  3SWC A;  3N71 A;  4J8O A;  3BO5 A;  4LDG A;  5CCM A;  3TG5 A;  4NJ5 A;  4JLG A;  3K5K A;  3HNA A;  3IHX A;  2BQZ A;  2IGQ A;  3MO0 A;  5LSX A;  5KJL A;  4IJ8 A;  3M57 A;  3MO5 A;  2RFI A;  3M58 A;  5F59 A;  4O30 A;  5T0K A;  3CBO A;  5JIY A;  3RIB A;  5T0M A;  3F9Z A;  5TH7 A;  3RJW A;  4J7I A;  3QWV A;  5AYF A;  3OXL A;  4AU7 A;  4Z4P A;  3OPE A;  5HI7 A;  4FMU A;  4C1Q A;  4MI5 A;  5KJM A;  3F9X A;  5EG2 A;  3RU0 A;  3OOI A;  3M59 A;  5TEG A;  3F9W A;  4QEN A;  4YPE A;  3M55 A;  3EP0 A;  3TG4 A;  5HQ8 A;  3S7B A;  3M5A A;  3FPD A;  2F69 A;  3VUZ A;  1N6C A;  4BUP A;  4WUY A;  5T5G A;  4J83 A;  3S7F A;  2R3A A;  4MI0 A;  3MO2 A;  5LSZ A;  1XQH A;  1PEG A;  2QPW A;  3PDN A;  5TTF A;  4YPA A;  3RAY A;  3KMJ A;  3MEK A;  3M56 A;  1N6A A; 
#chains in the Genus database with same CATH homology
 3CBP A;  4QEP A;  4I51 A;  5ARG A;  5EX3 A;  4IJD A;  2W5Z A;  4YND A;  5EX0 A;  5JIN A;  4H12 A;  3VV0 A;  2JV0 A;  4QEO A;  3F9Y A;  2G46 A;  3KMA A;  5CPR B;  4YNP A;  4E47 A;  1ZKK A;  3KMT A;  5JJ0 A;  3RQ4 A;  3CBM A;  5KJK A;  1N3J A;  3S7D A;  4RZ0 A;  5F6K C;  3DAL A;  1MVH A;  3OS5 A;  3M54 A;  5F5E A;  4O6F A;  3SW9 A;  1MUF A;  1ML9 A;  4J7F A;  3OXG A;  1O9S A;  4YNM A;  3S8P A;  5KJN A;  3S7J A;  1H3I A;  3QWP A;  4YPU A;  5ARF A;  4NVQ A;  1MVX A;  3OXF A;  5F6L A;  5CCL A;  2O8J A;  3DB5 A;  1MT6 A;  3M53 A;  3QWW A;  4JDS A;  2W5Y A;  5JHN A;  3SWC A;  3N71 A;  4J8O A;  3BO5 A;  4LDG A;  5CCM A;  3TG5 A;  4NJ5 A;  4JLG A;  3K5K A;  3HNA A;  3IHX A;  2BQZ A;  2IGQ A;  3MO0 A;  5LSX A;  5KJL A;  4IJ8 A;  3M57 A;  3MO5 A;  2RFI A;  3M58 A;  5F59 A;  4O30 A;  5T0K A;  3CBO A;  5JIY A;  3RIB A;  5T0M A;  3F9Z A;  5TH7 A;  3RJW A;  4J7I A;  3QWV A;  5AYF A;  3OXL A;  4AU7 A;  4Z4P A;  3OPE A;  5HI7 A;  4FMU A;  4C1Q A;  4MI5 A;  5KJM A;  3F9X A;  5EG2 A;  3RU0 A;  3OOI A;  3M59 A;  5TEG A;  3F9W A;  4QEN A;  4YPE A;  3M55 A;  3EP0 A;  3TG4 A;  5HQ8 A;  3S7B A;  3M5A A;  3FPD A;  2F69 A;  3VUZ A;  1N6C A;  4BUP A;  4WUY A;  5T5G A;  4J83 A;  3S7F A;  2R3A A;  4MI0 A;  3MO2 A;  5LSZ A;  1XQH A;  1PEG A;  2QPW A;  3PDN A;  5TTF A;  4YPA A;  3RAY A;  3KMJ A;  3MEK A;  3M56 A;  1N6A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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