2QWBA

The x-ray structure of a complex of sialic acid and a drug resistant variant r292k of tern n9 influenza virus neuraminidase
Total Genus 112
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
388
structure length
388
Chain Sequence
RDFNNLTKGLCTINSWHIYGKDNAVRIGEDSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRALISWPLSSPPTVYNSRVECIGWSSTSCHDGKTRMSICISGPNNNASAVIWYNRRPVTEINTWARNILRTQESECVCHNGVCPVVFTDGSATGPAETRIYYFKEGKILKWEPLAGTAKHIEECSCYGERAEITCTCKDNWQGSNRPVIRIDPVAMTHTSQYICSPVLTDNPRPNDPTVGKCNDPYPGNNNNGVKGFSYLDGVNTWLGRTISIASRSGYEMLKVPNALTDDKSKPTQGQTIVLNTDWSGYSGSFMDYWAEGECYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWDWPDGAKIEYFL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords NEURAMINIDASE
total genus 112
structure length 388
sequence length 388
ec nomenclature ec 3.2.1.18: Exo-alpha-sialidase.
pdb deposition date 1998-04-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00064 Neur Neuraminidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.10 Mainly Beta 6 Propeller Neuraminidase Neuraminidase 2qwbA00
2HTRA 1EUUA 2ZB5A 2ZB6A 3NSSA 4M3MA 1Z4ZA 4I00A 4XMIA 1E8UA 4FOWA 4WA3A 1NCDN 4MJVA 1KITA 1NNBA 3GVLA 4KS3A 4FPKA 2QWKA 2YA6A 2YA8A 1F8DA 1MS4A 1WCQA 1MS0A 1EUTA 1NCAN 4CPMA 5HX0A 3H72A 2A75A 1V2IA 4B7JA 2QWGA 2HU4A 4WEFA 1W21A 4MWXA 4CPYA 2YA5A 4FVKA 2QWFA 4FZHA 4CPLA 2F25A 4MWQA 2AEQA 1W0PA 3SLIA 1IVCA 1MR5A 4GZPA 4GDIA 3ALXA 4JF7A 3OPZA 4D8SA 4X6KA 4GZTA 5F9TA 4HZYA 5M1ZA 1L7FA 1MZ6A 1B9SA 1N1TA 1SO7A 3SALA 3CYEA 4YW1A 4XJAA 3ALWA 3NN9A 4KS2A 2BF6A 4FJ6A 2F13A 1MS1A 6NN9A 4XILA 1B9VA 2FHRA 4NCSA 3TI4A 3CL2A 4GZSA 4XJQA 2VK5A 4MWJA 3K39A 1S0JA 1A14N 4MWWA 1XOEA 1V3EA 1INHA 1L7GA 1BJIA 3TIBA 4QN6A 2VSKA 4XHBA 1W8OA 4HZXA 1DIMA 2BERA 2F12A 2SIMA 1S0IA 2HT8A 4MC7A 2VW2A 4K1JA 4XJ9A 4GJTA 1A4QA 4QN4A 1L7HA 1B9TA 2RKCA 2AEPA 2HTUA 3TI8A 1INGA 2HU0A 1INXA 4YZ2A 1A4GA 2BATA 5HUKA 3H71A 1NMCA 1W20A 4XJUA 4XJWA 4H52A 4WA4A 4X49A 2W5OA 4XHXA 1VCUA 4MZEA 2VSMA 1MS9A 1XOGA 4FP3A 4CPZA 4FOYA 1EURA 4K1KA 2VW0A 1F8EA 2XZIA 4YW4A 3GVKA 4XIKA 1MZ5A 1IVGA 1USXA 4MWVA 4M4UA 4FPJA 3K37A 4QN5A 4WA5A 4M4VA 4YZ3A 2F26A 1NNCA 1NSCA 2C4AA 1V0EA 1DILA 1Z4YA 4XMAA 4GZWA 3INBA 1N1VA 4HZWA 2YA4A 4KS4A 3W09A 4KS5A 4GZOA 2XZJA 2VWDA 4K1HA 4M4NA 2AGSA 1IVEA 2XCYA 2SILA 1SLLA 4FPLA 2YDTA 4B7RA 4YZ1A 1IVBA 4HZZA 2VW1A 4MX0A 1Z50A 4FOVA 4X4AA 2YA7A 3K36A 1V0FA 4K3YA 1MS5A 2HTWA 1IVDA 2QWJA 5NN9A 2W5NA 4XYXA 1E8VA 3B69A 1F8BA 3O9KA 1NCCN 3T1EA 1NMAN 1NSBA 2F11A 2QWDA 3B7EA 2F27A 4J9TA 2HTQA 4QN3A 4CPNA 2HTVA 2W20A 1NMBN 4DGRA 3SILA 4XJRA 4B7NA 4XJZA 2HT7A 3TICA 4FQ4A 1MS3A 4GZXA 2XZKA 1Z4XA 1MWEA 4FPEA 2F24A 3H73A 5HUGA 3H6JA 4GDJA 4SLIA 1EUSA 1V3CA 3TIAA 1NSDA 1V0ZA 1N1SA 3PJQA 7NN9A 3TI5A 3A71A 4QN7A 3SANA 5JYYA 2F28A 3O9JA 1W0OA 2QWBA 4CPOA 4YZ5A 2F0ZA 2HTYA 3TI3A 1Z4VA 4UF7A 4FPFA 1NNAA 4GEZA 4MJUA 4XOGA 2AH2A 4FPYA 3JU4A 2QWAA 4X47A 2X9MA 1VCJA 4MWLA 3D11A 4MZAA 4XIOA 2BZDA 2QWEA 1SNTA 2W38A 4XE9A 2F29A 1INVA 1V3DA 2HT5A 4GZQA 1W8NA 4FP2A 2QWCA 1NCBN 4NC5A 4KS1A 1Z4WA 3CL0A 4YW5A 2F10A 2VK6A 2SLIA 2CMLA 4BBWA 4YZ4A 4MWYA 4H53A 4FOQA 4HZVA 3K38A 1W1XA 2VVZA 1INWA 3D12A 1F8CA 3A72A 4YW3A 2QWHA 5HUNA 3GVJA 3K3AA 4MWRA 1SLIA 4FPCA 1USRA 3TI6A 1INFA 1IVFA 2B8HA 5HUMA 4XJ8A 2JKBA 4YW2A 4FPHA 4WEGA 4FPGA 3BEQA 5B2DA 2C4LA 1E8TA 4NN9A 4GB1A 1N1YA 4QNPA 2YDPA 4B7MA 2QWIA 1V3BA 1INYA 4FPOB 4Q6KA 3CKZA 2VK7A 4HIZA 1WCSA 1NN2A 4K1IA 5B2CA 4MWUA 4B7QA 1MS8A
chains in the Genus database with same CATH superfamily
2FP8A 2HTRA 4PWZA 1EUUA 2ZB5A 2ZB6A 3NSSA 4M3MA 1Z4ZA 4I00A 4XMIA 2FP9A 3SOVA 1E8UA 4IQKA 4FOWA 4WA3A 1NCDN 3HRPA 4MJVA 4N1BA 1KITA 1NNBA 3GVLA 4KS3A 4FPKA 2QWKA 2YA6A 2YA8A 1OFZA 3AMSA 1F8DA 1MS4A 4CHBA 3WW9A 1X2RA 2QE8A 3V1SA 1WCQA 5H47A 1MS0A 5GX1A 1EUTA 1NCAN 4HHOA 4CPMA 3LI5A 5HX0A 3H72A 2A75A 3VNGA 1V2IA 2GVVA 1SUUA 1V04A 4B7JA 2QWGA 2HU4A 4WEFA 4D52B 1QLGA 1W21A 2GVXA 4MWXA 5FNRA 5GX2A 4CPYA 1S18A 3FW0A 2IAWA 3Q6PA 2YA5A 4FVKA 2QWFA 4FZHA 3LI3A 2GVUA 4CPLA 4A0PA 2F25A 4MWQA 2AEQA 1W0PA 3SLIA 1IVCA 2ZZKA 1MR5A 4GZPA 4GDIA 3ALXA 4JF7A 3OPZA 4D8SA 4X6KA 4D52A 1Q7FA 1X2JA 4GZTA 5F9TA 4HZYA 5M1ZA 1L7FA 1MZ6A 4O5SA 1B9SA 1N1TA 1SO7A 3SALA 3CYEA 3S8ZA 4YW1A 4XJAA 5FWWA 4GN8A 3ALWA 3NN9A 4KS2A 2BF6A 4FJ6A 2IAPA 2F13A 1MS1A 4ZLRA 4IMBA 6NN9A 4XILA 1B9VA 2FHRA 4NCSA 3TI4A 3CL2A 1K32A 2FPCA 4GZSA 3DASA 2IVZA 4XJQA 2VK5A 4MWJA 3K39A 1S0JA 1A14N 4MWWA 1XOEA 2DG0A 1V3EA 1ZI0A 3G4EA 1INHA 1L7GA 3LI4A 1BJIA 3TIBA 4GNAA 4R40A 4QN6A 2VSKA 4XHBA 1W8OA 4HZXA 1C9UA 1DIMA 2BERA 2F12A 2SIMA 4HW6A 1S0IA 2GHSA 2HT8A 4MC7A 2VW2A 4K1JA 2DG1A 3DR2A 4XJ9A 3I1CA 4GJTA 1A4QA 4QN4A 1L7HA 1B9TA 2RKCA 2AEPA 2HTUA 3TI8A 1INGA 1N7DA 1H6LA 2HU0A 1INXA 4YZ2A 1A4GA 1CVMA 3SOBB 2BATA 5HUKA 3H71A 1NMCA 1N6DA 1W20A 4XJUA 4XJWA 4H52A 4WA4A 2IAQA 5GX4A 3FVZA 4X49A 2W5OA 4XHXA 1VCUA 4MZEA 2VSMA 3SREA 1RWLA 1MS9A 5D9DA 1XOGA 4FP3A 4CPZA 4FOYA 3TC9A 3A9HA 1EURA 2DSOA 5FNQA 2GVWA 4K1KA 2VW0A 1CQ1A 4CH9A 4ASCA 1F8EA 2XZIA 4YW4A 5CGJA 2H2UA 3GVKA 4XIKA 1MZ5A 3Q6KA 4UOUA 1IVGA 4G3NA 1USXA 4IFJA 4MWVA 4M4UA 4FPJA 3K37A 4QN5A 4WA5A 4M4VA 4YZ3A 5FZNA 2ZWAA 2F26A 1NNCA 1NSCA 2C4AA 1V0EA 1DILA 2POOA 1CRZA 1Z4YA 4XMAA 4GZWA 2IAVA 2ZW9A 1IJQA 3INBA 1N1VA 4HZWA 2YA4A 4KS4A 3W09A 4KS5A 2IATA 4GZOA 4C1YA 2IAXA 2IARA 3WN7A 2XZJA 2VWDA 4K1HA 4M4NA 2AGSA 1IVEA 2XCYA 2SILA 4DG6A 1SLLA 3V64C 3S94A 4IFNX 1NPEA 4FPLA 2YDTA 4B7RA 1RWIA 4YZ1A 3ZGDA 1IVBA 4HZZA 3SOQA 3E5ZA 1U6DX 2VW1A 4MX0A 5D9CA 1Z50A 2HQSA 4FOVA 4X4AA 2YA7A 3K36A 4AGIA 1V0FA 4K3YA 1MS5A 2HTWA 1IVDA 3S2KA 2QWJA 5NN9A 5GX3A 2W5NA 3ADEA 4XYXA 4GNBA 1E8VA 3B69A 1F8BA 3O9KA 1NCCN 3II7A 3ZGCA 3T1EA 4IN4A 4ZY3A 1NMAN 1NSBA 2F11A 2QWDA 3B7EA 4CSDA 3U0SA 2F27A 4J9TA 2HTQA 4QN3A 4CPNA 2HTVA 2W20A 1NMBN 2W8BA 3WWAA 4DGRA 3SILA 4XJRA 5FNTA 2V91A 4B7NA 4XJZA 2HT7A 4IYGA 3TICA 4L7BA 2H2NA 4FQ4A 1MS3A 4GZXA 2IAUA 5FNUA 2XZKA 1Z4XA 1MWEA 4FPEA 5GTQA 2F24A 3H73A 5HUGA 3H6JA 4GDJA 4ZGCA 3UC1A 4SLIA 5FNSA 3WDZA 1EUSA 1V3CA 3TIAA 3O4PA 4XMBA 1NSDA 4D52C 3KGGA 1IUCA 1V0ZA 1N1SA 3NO0A 3PJQA 3V65B 7NN9A 4YY8A 3TI5A 3A71A 1PJXA 4QN7A 3SANA 5JYYA 2F28A 4AHAA 3O9JA 1W0OA 2QWBA 4CPOA 1WP5A 2IAOA 4YZ5A 2FLUX 2F0ZA 2HTYA 5EO8A 1N6EA 3TI3A 1Z4VA 4UF7A 4FPFA 4AGTA 1NNAA 3L6VA 4GEZA 4MJUA 4IFLX 4XOGA 2AH2A 4FPYA 3S8VA 4L7CA 5EO7A 3JU4A 3P5BL 2QWAA 5GX5A 4X47A 2X9MA 1VCJA 4MWLA 3D11A 4C1YB 4MZAA 2OJHA 4GNCA 2WOZA 3G4HA 4XIOA 2BZDA 2QWEA 2Z32A 1SNTA 2W38A 1POOA 4XE9A 5FZJA 2F29A 1INVA 1E1AA 1V3DA 2HT5A 4GZQA 2IASA 2FPBA 2VPJA 1ZGKA 1W8NA 4GN9A 4FP2A 4L7DA 2QWCA 1NCBN 3SRGA 4NC5A 4KS1A 4O5TA 3AMRA 3VNHA 1Z4WA 3CL0A 4YW5A 2F10A 1CRUA 2P4OA 2VK6A 5EX7A 3A9GA 3HLIA 2SLIA 3IAXA 2CMLA 4BBWA 4YZ4A 5D9BA 4MWYA 2XN4A 2G8SA 4H53A 4FOQA 4HZVA 3K38A 4JMLA 1W1XA 2ISMA 2VVZA 4D4UA 1S1DA 1INWA 3D12A 1F8CA 3A72A 4YW3A 2QWHA 5HUNA 3GVJA 3K3AA 4AH4A 4MWRA 1SLIA 4FPCA 1USRA 2VAQA 3TI6A 1INFA 1IVFA 2B8HA 3HLHA 5HUMA 4XJ8A 2DYHA 4Q1UA 2JKBA 2W8BB 4YW2A 4FPHA 4WEGA 1QBIA 4FPGA 3BEQA 3Q6TA 5B2DA 2C4LA 3BYCA 1E8TA 4NN9A 1C5KA 1N6FA 4GB1A 1N1YA 4QNPA 2YDPA 4B7MA 2QWIA 4HHQA 1V3BA 1INYA 4FPOB 4Q6KA 3KYAA 3CKZA 5F72C 2VK7A 4HIZA 1WCSA 1NN2A 4GN7A 4K1IA 5B2CA 1IUBA 4MWUA 4B7QA 1MS8A
chains in the Genus database with same CATH topology
2HTRA 1EUUA 2ZB5A 2ZB6A 3NSSA 4M3MA 1Z4ZA 4I00A 4XMIA 1E8UA 4FOWA 4WA3A 1NCDN 4MJVA 1KITA 1NNBA 3GVLA 4KS3A 4FPKA 2QWKA 2YA6A 2YA8A 1F8DA 1MS4A 1WCQA 1MS0A 1EUTA 1NCAN 4CPMA 5HX0A 3H72A 2A75A 1V2IA 4B7JA 2QWGA 2HU4A 4WEFA 1W21A 4MWXA 4CPYA 1S18A 2YA5A 4FVKA 2QWFA 4FZHA 4CPLA 2F25A 4MWQA 2AEQA 1W0PA 3SLIA 1IVCA 1MR5A 4GZPA 4GDIA 3ALXA 4JF7A 3OPZA 4D8SA 4X6KA 4GZTA 5F9TA 4HZYA 5M1ZA 1L7FA 1MZ6A 1B9SA 1N1TA 1SO7A 3SALA 3CYEA 4YW1A 4XJAA 3ALWA 3NN9A 4KS2A 2BF6A 4FJ6A 2F13A 1MS1A 6NN9A 4XILA 1B9VA 2FHRA 4NCSA 3TI4A 3CL2A 4GZSA 4XJQA 2VK5A 4MWJA 3K39A 1S0JA 1A14N 4MWWA 1XOEA 1V3EA 1INHA 1L7GA 1BJIA 3TIBA 4QN6A 2VSKA 4XHBA 1W8OA 4HZXA 1DIMA 2BERA 2F12A 2SIMA 1S0IA 2HT8A 4MC7A 2VW2A 4K1JA 4XJ9A 4GJTA 1A4QA 4QN4A 1L7HA 1B9TA 2RKCA 2AEPA 2HTUA 3TI8A 1INGA 2HU0A 1INXA 4YZ2A 1A4GA 2BATA 5HUKA 3H71A 1NMCA 1W20A 4XJUA 4XJWA 4H52A 4WA4A 4X49A 2W5OA 4XHXA 1VCUA 4MZEA 2VSMA 1MS9A 1XOGA 4FP3A 4CPZA 4FOYA 1EURA 4K1KA 2VW0A 1F8EA 2XZIA 4YW4A 2H2UA 3GVKA 4XIKA 1MZ5A 1IVGA 1USXA 4MWVA 4M4UA 4FPJA 3K37A 4QN5A 4WA5A 4M4VA 4YZ3A 2F26A 1NNCA 1NSCA 2C4AA 1V0EA 1DILA 1Z4YA 4XMAA 4GZWA 3INBA 1N1VA 4HZWA 2YA4A 4KS4A 3W09A 4KS5A 4GZOA 2XZJA 2VWDA 4K1HA 4M4NA 2AGSA 1IVEA 2XCYA 2SILA 1SLLA 4FPLA 2YDTA 4B7RA 4YZ1A 1IVBA 4HZZA 2VW1A 4MX0A 1Z50A 4FOVA 4X4AA 2YA7A 3K36A 1V0FA 4K3YA 1MS5A 2HTWA 1IVDA 2QWJA 5NN9A 2W5NA 4XYXA 1E8VA 3B69A 1F8BA 3O9KA 1NCCN 3T1EA 1NMAN 1NSBA 2F11A 2QWDA 3B7EA 2F27A 4J9TA 2HTQA 4QN3A 4CPNA 2HTVA 2W20A 1NMBN 4DGRA 3SILA 4XJRA 4B7NA 4XJZA 2HT7A 3TICA 2H2NA 4FQ4A 1MS3A 4GZXA 2XZKA 1Z4XA 1MWEA 4FPEA 2F24A 3H73A 5HUGA 3H6JA 4GDJA 4SLIA 1EUSA 1V3CA 3TIAA 1NSDA 1V0ZA 1N1SA 3PJQA 7NN9A 3TI5A 3A71A 4QN7A 3SANA 5JYYA 2F28A 3O9JA 1W0OA 2QWBA 4CPOA 4YZ5A 2F0ZA 2HTYA 3TI3A 1Z4VA 4UF7A 4FPFA 1NNAA 4GEZA 4MJUA 4XOGA 2AH2A 4FPYA 3JU4A 2QWAA 4X47A 2X9MA 1VCJA 4MWLA 3D11A 4MZAA 4XIOA 2BZDA 2QWEA 1SNTA 2W38A 4XE9A 2F29A 1INVA 1V3DA 2HT5A 4GZQA 1W8NA 4FP2A 2QWCA 1NCBN 4NC5A 4KS1A 1Z4WA 3CL0A 4YW5A 2F10A 2VK6A 2SLIA 2CMLA 4BBWA 4YZ4A 4MWYA 4H53A 4FOQA 4HZVA 3K38A 1W1XA 2VVZA 1S1DA 1INWA 3D12A 1F8CA 3A72A 4YW3A 2QWHA 5HUNA 3GVJA 3K3AA 4MWRA 1SLIA 4FPCA 1USRA 3TI6A 1INFA 1IVFA 2B8HA 5HUMA 4XJ8A 2JKBA 4YW2A 4FPHA 4WEGA 4FPGA 3BEQA 5B2DA 2C4LA 1E8TA 4NN9A 4GB1A 1N1YA 4QNPA 2YDPA 4B7MA 2QWIA 1V3BA 1INYA 4FPOB 4Q6KA 3CKZA 2VK7A 4HIZA 1WCSA 1NN2A 4K1IA 5B2CA 4MWUA 4B7QA 1MS8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HTR A;  1EUU A;  2ZB5 A;  2ZB6 A;  3NSS A;  4M3M A;  1Z4Z A;  4I00 A;  4XMI A;  1E8U A;  4FOW A;  4WA3 A;  1NCD N;  4MJV A;  1KIT A;  1NNB A;  3GVL A;  4KS3 A;  4FPK A;  2QWK A;  2YA6 A;  2YA8 A;  1F8D A;  1MS4 A;  1WCQ A;  1MS0 A;  1EUT A;  1NCA N;  4CPM A;  5HX0 A;  3H72 A;  2A75 A;  1V2I A;  4B7J A;  2QWG A;  2HU4 A;  4WEF A;  1W21 A;  4MWX A;  4CPY A;  2YA5 A;  4FVK A;  2QWF A;  4FZH A;  4CPL A;  2F25 A;  4MWQ A;  2AEQ A;  1W0P A;  3SLI A;  1IVC A;  1MR5 A;  4GZP A;  4GDI A;  3ALX A;  4JF7 A;  3OPZ A;  4D8S A;  4X6K A;  4GZT A;  5F9T A;  4HZY A;  5M1Z A;  1L7F A;  1MZ6 A;  1B9S A;  1N1T A;  1SO7 A;  3SAL A;  3CYE A;  4YW1 A;  4XJA A;  3ALW A;  3NN9 A;  4KS2 A;  2BF6 A;  4FJ6 A;  2F13 A;  1MS1 A;  6NN9 A;  4XIL A;  1B9V A;  2FHR A;  4NCS A;  3TI4 A;  3CL2 A;  4GZS A;  4XJQ A;  2VK5 A;  4MWJ A;  3K39 A;  1S0J A;  1A14 N;  4MWW A;  1XOE A;  1V3E A;  1INH A;  1L7G A;  1BJI A;  3TIB A;  4QN6 A;  2VSK A;  4XHB A;  1W8O A;  4HZX A;  1DIM A;  2BER A;  2F12 A;  2SIM A;  1S0I A;  2HT8 A;  4MC7 A;  2VW2 A;  4K1J A;  4XJ9 A;  4GJT A;  1A4Q A;  4QN4 A;  1L7H A;  1B9T A;  2RKC A;  2AEP A;  2HTU A;  3TI8 A;  1ING A;  2HU0 A;  1INX A;  4YZ2 A;  1A4G A;  2BAT A;  5HUK A;  3H71 A;  1NMC A;  1W20 A;  4XJU A;  4XJW A;  4H52 A;  4WA4 A;  4X49 A;  2W5O A;  4XHX A;  1VCU A;  4MZE A;  2VSM A;  1MS9 A;  1XOG A;  4FP3 A;  4CPZ A;  4FOY A;  1EUR A;  4K1K A;  2VW0 A;  1F8E A;  2XZI A;  4YW4 A;  3GVK A;  4XIK A;  1MZ5 A;  1IVG A;  1USX A;  4MWV A;  4M4U A;  4FPJ A;  3K37 A;  4QN5 A;  4WA5 A;  4M4V A;  4YZ3 A;  2F26 A;  1NNC A;  1NSC A;  2C4A A;  1V0E A;  1DIL A;  1Z4Y A;  4XMA A;  4GZW A;  3INB A;  1N1V A;  4HZW A;  2YA4 A;  4KS4 A;  3W09 A;  4KS5 A;  4GZO A;  2XZJ A;  2VWD A;  4K1H A;  4M4N A;  2AGS A;  1IVE A;  2XCY A;  2SIL A;  1SLL A;  4FPL A;  2YDT A;  4B7R A;  4YZ1 A;  1IVB A;  4HZZ A;  2VW1 A;  4MX0 A;  1Z50 A;  4FOV A;  4X4A A;  2YA7 A;  3K36 A;  1V0F A;  4K3Y A;  1MS5 A;  2HTW A;  1IVD A;  2QWJ A;  5NN9 A;  2W5N A;  4XYX A;  1E8V A;  3B69 A;  1F8B A;  3O9K A;  1NCC N;  3T1E A;  1NMA N;  1NSB A;  2F11 A;  2QWD A;  3B7E A;  2F27 A;  4J9T A;  2HTQ A;  4QN3 A;  4CPN A;  2HTV A;  2W20 A;  1NMB N;  4DGR A;  3SIL A;  4XJR A;  4B7N A;  4XJZ A;  2HT7 A;  3TIC A;  4FQ4 A;  1MS3 A;  4GZX A;  2XZK A;  1Z4X A;  1MWE A;  4FPE A;  2F24 A;  3H73 A;  5HUG A;  3H6J A;  4GDJ A;  4SLI A;  1EUS A;  1V3C A;  3TIA A;  1NSD A;  1V0Z A;  1N1S A;  3PJQ A;  7NN9 A;  3TI5 A;  3A71 A;  4QN7 A;  3SAN A;  5JYY A;  2F28 A;  3O9J A;  1W0O A;  2QWB A;  4CPO A;  4YZ5 A;  2F0Z A;  2HTY A;  3TI3 A;  1Z4V A;  4UF7 A;  4FPF A;  1NNA A;  4GEZ A;  4MJU A;  4XOG A;  2AH2 A;  4FPY A;  3JU4 A;  2QWA A;  4X47 A;  2X9M A;  1VCJ A;  4MWL A;  3D11 A;  4MZA A;  4XIO A;  2BZD A;  2QWE A;  1SNT A;  2W38 A;  4XE9 A;  2F29 A;  1INV A;  1V3D A;  2HT5 A;  4GZQ A;  1W8N A;  4FP2 A;  2QWC A;  1NCB N;  4NC5 A;  4KS1 A;  1Z4W A;  3CL0 A;  4YW5 A;  2F10 A;  2VK6 A;  2SLI A;  2CML A;  4BBW A;  4YZ4 A;  4MWY A;  4H53 A;  4FOQ A;  4HZV A;  3K38 A;  1W1X A;  2VVZ A;  1INW A;  3D12 A;  1F8C A;  3A72 A;  4YW3 A;  2QWH A;  5HUN A;  3GVJ A;  3K3A A;  4MWR A;  1SLI A;  4FPC A;  1USR A;  3TI6 A;  1INF A;  1IVF A;  2B8H A;  5HUM A;  4XJ8 A;  2JKB A;  4YW2 A;  4FPH A;  4WEG A;  4FPG A;  3BEQ A;  5B2D A;  2C4L A;  1E8T A;  4NN9 A;  4GB1 A;  1N1Y A;  4QNP A;  2YDP A;  4B7M A;  2QWI A;  1V3B A;  1INY A;  4FPO B;  4Q6K A;  3CKZ A;  2VK7 A;  4HIZ A;  1WCS A;  1NN2 A;  4K1I A;  5B2C A;  4MWU A;  4B7Q A;  1MS8 A; 
#chains in the Genus database with same CATH topology
 2FP8 A;  2HTR A;  4PWZ A;  1EUU A;  2ZB5 A;  2ZB6 A;  3NSS A;  4M3M A;  1Z4Z A;  4I00 A;  4XMI A;  2FP9 A;  3SOV A;  1E8U A;  4IQK A;  4FOW A;  4WA3 A;  1NCD N;  3HRP A;  4MJV A;  4N1B A;  1KIT A;  1NNB A;  3GVL A;  4KS3 A;  4FPK A;  2QWK A;  2YA6 A;  2YA8 A;  1OFZ A;  3AMS A;  1F8D A;  1MS4 A;  4CHB A;  3WW9 A;  1X2R A;  2QE8 A;  3V1S A;  1WCQ A;  5H47 A;  1MS0 A;  5GX1 A;  1EUT A;  1NCA N;  4HHO A;  4CPM A;  3LI5 A;  5HX0 A;  3H72 A;  2A75 A;  3VNG A;  1V2I A;  2GVV A;  1SUU A;  1V04 A;  4B7J A;  2QWG A;  2HU4 A;  4WEF A;  4D52 B;  1QLG A;  1W21 A;  2GVX A;  4MWX A;  5FNR A;  5GX2 A;  4CPY A;  1S18 A;  3FW0 A;  2IAW A;  3Q6P A;  2YA5 A;  4FVK A;  2QWF A;  4FZH A;  3LI3 A;  2GVU A;  4CPL A;  4A0P A;  2F25 A;  4MWQ A;  2AEQ A;  1W0P A;  3SLI A;  1IVC A;  2ZZK A;  1MR5 A;  4GZP A;  4GDI A;  3ALX A;  4JF7 A;  3OPZ A;  4D8S A;  4X6K A;  4D52 A;  1Q7F A;  1X2J A;  4GZT A;  5F9T A;  4HZY A;  5M1Z A;  1L7F A;  1MZ6 A;  4O5S A;  1B9S A;  1N1T A;  1SO7 A;  3SAL A;  3CYE A;  3S8Z A;  4YW1 A;  4XJA A;  5FWW A;  4GN8 A;  3ALW A;  3NN9 A;  4KS2 A;  2BF6 A;  4FJ6 A;  2IAP A;  2F13 A;  1MS1 A;  4ZLR A;  4IMB A;  6NN9 A;  4XIL A;  1B9V A;  2FHR A;  4NCS A;  3TI4 A;  3CL2 A;  1K32 A;  2FPC A;  4GZS A;  3DAS A;  2IVZ A;  4XJQ A;  2VK5 A;  4MWJ A;  3K39 A;  1S0J A;  1A14 N;  4MWW A;  1XOE A;  2DG0 A;  1V3E A;  1ZI0 A;  3G4E A;  1INH A;  1L7G A;  3LI4 A;  1BJI A;  3TIB A;  4GNA A;  4R40 A;  4QN6 A;  2VSK A;  4XHB A;  1W8O A;  4HZX A;  1C9U A;  1DIM A;  2BER A;  2F12 A;  2SIM A;  4HW6 A;  1S0I A;  2GHS A;  2HT8 A;  4MC7 A;  2VW2 A;  4K1J A;  2DG1 A;  3DR2 A;  4XJ9 A;  3I1C A;  4GJT A;  1A4Q A;  4QN4 A;  1L7H A;  1B9T A;  2RKC A;  2AEP A;  2HTU A;  3TI8 A;  1ING A;  1N7D A;  1H6L A;  2HU0 A;  1INX A;  4YZ2 A;  1A4G A;  1CVM A;  3SOB B;  2BAT A;  5HUK A;  3H71 A;  1NMC A;  1N6D A;  1W20 A;  4XJU A;  4XJW A;  4H52 A;  4WA4 A;  2IAQ A;  5GX4 A;  3FVZ A;  4X49 A;  2W5O A;  4XHX A;  1VCU A;  4MZE A;  2VSM A;  3SRE A;  1RWL A;  1MS9 A;  5D9D A;  1XOG A;  4FP3 A;  4CPZ A;  4FOY A;  3TC9 A;  3A9H A;  1EUR A;  2DSO A;  5FNQ A;  2GVW A;  4K1K A;  2VW0 A;  1CQ1 A;  4CH9 A;  4ASC A;  1F8E A;  2XZI A;  4YW4 A;  5CGJ A;  2H2U A;  3GVK A;  4XIK A;  1MZ5 A;  3Q6K A;  4UOU A;  1IVG A;  4G3N A;  1USX A;  4IFJ A;  4MWV A;  4M4U A;  4FPJ A;  3K37 A;  4QN5 A;  4WA5 A;  4M4V A;  4YZ3 A;  5FZN A;  2ZWA A;  2F26 A;  1NNC A;  1NSC A;  2C4A A;  1V0E A;  1DIL A;  2POO A;  1CRZ A;  1Z4Y A;  4XMA A;  4GZW A;  2IAV A;  2ZW9 A;  1IJQ A;  3INB A;  1N1V A;  4HZW A;  2YA4 A;  4KS4 A;  3W09 A;  4KS5 A;  2IAT A;  4GZO A;  4C1Y A;  2IAX A;  2IAR A;  3WN7 A;  2XZJ A;  2VWD A;  4K1H A;  4M4N A;  2AGS A;  1IVE A;  2XCY A;  2SIL A;  4DG6 A;  1SLL A;  3V64 C;  3S94 A;  4IFN X;  1NPE A;  4FPL A;  2YDT A;  4B7R A;  1RWI A;  4YZ1 A;  3ZGD A;  1IVB A;  4HZZ A;  3SOQ A;  3E5Z A;  1U6D X;  2VW1 A;  4MX0 A;  5D9C A;  1Z50 A;  2HQS A;  4FOV A;  4X4A A;  2YA7 A;  3K36 A;  4AGI A;  1V0F A;  4K3Y A;  1MS5 A;  2HTW A;  1IVD A;  3S2K A;  2QWJ A;  5NN9 A;  5GX3 A;  2W5N A;  3ADE A;  4XYX A;  4GNB A;  1E8V A;  3B69 A;  1F8B A;  3O9K A;  1NCC N;  3II7 A;  3ZGC A;  3T1E A;  4IN4 A;  4ZY3 A;  1NMA N;  1NSB A;  2F11 A;  2QWD A;  3B7E A;  4CSD A;  3U0S A;  2F27 A;  4J9T A;  2HTQ A;  4QN3 A;  4CPN A;  2HTV A;  2W20 A;  1NMB N;  2W8B A;  3WWA A;  4DGR A;  3SIL A;  4XJR A;  5FNT A;  2V91 A;  4B7N A;  4XJZ A;  2HT7 A;  4IYG A;  3TIC A;  4L7B A;  2H2N A;  4FQ4 A;  1MS3 A;  4GZX A;  2IAU A;  5FNU A;  2XZK A;  1Z4X A;  1MWE A;  4FPE A;  5GTQ A;  2F24 A;  3H73 A;  5HUG A;  3H6J A;  4GDJ A;  4ZGC A;  3UC1 A;  4SLI A;  5FNS A;  3WDZ A;  1EUS A;  1V3C A;  3TIA A;  3O4P A;  4XMB A;  1NSD A;  4D52 C;  3KGG A;  1IUC A;  1V0Z A;  1N1S A;  3NO0 A;  3PJQ A;  3V65 B;  7NN9 A;  4YY8 A;  3TI5 A;  3A71 A;  1PJX A;  4QN7 A;  3SAN A;  5JYY A;  2F28 A;  4AHA A;  3O9J A;  1W0O A;  2QWB A;  4CPO A;  1WP5 A;  2IAO A;  4YZ5 A;  2FLU X;  2F0Z A;  2HTY A;  5EO8 A;  1N6E A;  3TI3 A;  1Z4V A;  4UF7 A;  4FPF A;  4AGT A;  1NNA A;  3L6V A;  4GEZ A;  4MJU A;  4IFL X;  4XOG A;  2AH2 A;  4FPY A;  3S8V A;  4L7C A;  5EO7 A;  3JU4 A;  3P5B L;  2QWA A;  5GX5 A;  4X47 A;  2X9M A;  1VCJ A;  4MWL A;  3D11 A;  4C1Y B;  4MZA A;  2OJH A;  4GNC A;  2WOZ A;  3G4H A;  4XIO A;  2BZD A;  2QWE A;  2Z32 A;  1SNT A;  2W38 A;  1POO A;  4XE9 A;  5FZJ A;  2F29 A;  1INV A;  1E1A A;  1V3D A;  2HT5 A;  4GZQ A;  2IAS A;  2FPB A;  2VPJ A;  1ZGK A;  1W8N A;  4GN9 A;  4FP2 A;  4L7D A;  2QWC A;  1NCB N;  3SRG A;  4NC5 A;  4KS1 A;  4O5T A;  3AMR A;  3VNH A;  1Z4W A;  3CL0 A;  4YW5 A;  2F10 A;  1CRU A;  2P4O A;  2VK6 A;  5EX7 A;  3A9G A;  3HLI A;  2SLI A;  3IAX A;  2CML A;  4BBW A;  4YZ4 A;  5D9B A;  4MWY A;  2XN4 A;  2G8S A;  4H53 A;  4FOQ A;  4HZV A;  3K38 A;  4JML A;  1W1X A;  2ISM A;  2VVZ A;  4D4U A;  1S1D A;  1INW A;  3D12 A;  1F8C A;  3A72 A;  4YW3 A;  2QWH A;  5HUN A;  3GVJ A;  3K3A A;  4AH4 A;  4MWR A;  1SLI A;  4FPC A;  1USR A;  2VAQ A;  3TI6 A;  1INF A;  1IVF A;  2B8H A;  3HLH A;  5HUM A;  4XJ8 A;  2DYH A;  4Q1U A;  2JKB A;  2W8B B;  4YW2 A;  4FPH A;  4WEG A;  1QBI A;  4FPG A;  3BEQ A;  3Q6T A;  5B2D A;  2C4L A;  3BYC A;  1E8T A;  4NN9 A;  1C5K A;  1N6F A;  4GB1 A;  1N1Y A;  4QNP A;  2YDP A;  4B7M A;  2QWI A;  4HHQ A;  1V3B A;  1INY A;  4FPO B;  4Q6K A;  3KYA A;  3CKZ A;  5F72 C;  2VK7 A;  4HIZ A;  1WCS A;  1NN2 A;  4GN7 A;  4K1I A;  5B2C A;  1IUB A;  4MWU A;  4B7Q A;  1MS8 A; 
#chains in the Genus database with same CATH homology
 2HTR A;  1EUU A;  2ZB5 A;  2ZB6 A;  3NSS A;  4M3M A;  1Z4Z A;  4I00 A;  4XMI A;  1E8U A;  4FOW A;  4WA3 A;  1NCD N;  4MJV A;  1KIT A;  1NNB A;  3GVL A;  4KS3 A;  4FPK A;  2QWK A;  2YA6 A;  2YA8 A;  1F8D A;  1MS4 A;  1WCQ A;  1MS0 A;  1EUT A;  1NCA N;  4CPM A;  5HX0 A;  3H72 A;  2A75 A;  1V2I A;  4B7J A;  2QWG A;  2HU4 A;  4WEF A;  1W21 A;  4MWX A;  4CPY A;  1S18 A;  2YA5 A;  4FVK A;  2QWF A;  4FZH A;  4CPL A;  2F25 A;  4MWQ A;  2AEQ A;  1W0P A;  3SLI A;  1IVC A;  1MR5 A;  4GZP A;  4GDI A;  3ALX A;  4JF7 A;  3OPZ A;  4D8S A;  4X6K A;  4GZT A;  5F9T A;  4HZY A;  5M1Z A;  1L7F A;  1MZ6 A;  1B9S A;  1N1T A;  1SO7 A;  3SAL A;  3CYE A;  4YW1 A;  4XJA A;  3ALW A;  3NN9 A;  4KS2 A;  2BF6 A;  4FJ6 A;  2F13 A;  1MS1 A;  6NN9 A;  4XIL A;  1B9V A;  2FHR A;  4NCS A;  3TI4 A;  3CL2 A;  4GZS A;  4XJQ A;  2VK5 A;  4MWJ A;  3K39 A;  1S0J A;  1A14 N;  4MWW A;  1XOE A;  1V3E A;  1INH A;  1L7G A;  1BJI A;  3TIB A;  4QN6 A;  2VSK A;  4XHB A;  1W8O A;  4HZX A;  1DIM A;  2BER A;  2F12 A;  2SIM A;  1S0I A;  2HT8 A;  4MC7 A;  2VW2 A;  4K1J A;  4XJ9 A;  4GJT A;  1A4Q A;  4QN4 A;  1L7H A;  1B9T A;  2RKC A;  2AEP A;  2HTU A;  3TI8 A;  1ING A;  2HU0 A;  1INX A;  4YZ2 A;  1A4G A;  2BAT A;  5HUK A;  3H71 A;  1NMC A;  1W20 A;  4XJU A;  4XJW A;  4H52 A;  4WA4 A;  4X49 A;  2W5O A;  4XHX A;  1VCU A;  4MZE A;  2VSM A;  1MS9 A;  1XOG A;  4FP3 A;  4CPZ A;  4FOY A;  1EUR A;  4K1K A;  2VW0 A;  1F8E A;  2XZI A;  4YW4 A;  2H2U A;  3GVK A;  4XIK A;  1MZ5 A;  1IVG A;  1USX A;  4MWV A;  4M4U A;  4FPJ A;  3K37 A;  4QN5 A;  4WA5 A;  4M4V A;  4YZ3 A;  2F26 A;  1NNC A;  1NSC A;  2C4A A;  1V0E A;  1DIL A;  1Z4Y A;  4XMA A;  4GZW A;  3INB A;  1N1V A;  4HZW A;  2YA4 A;  4KS4 A;  3W09 A;  4KS5 A;  4GZO A;  2XZJ A;  2VWD A;  4K1H A;  4M4N A;  2AGS A;  1IVE A;  2XCY A;  2SIL A;  1SLL A;  4FPL A;  2YDT A;  4B7R A;  4YZ1 A;  1IVB A;  4HZZ A;  2VW1 A;  4MX0 A;  1Z50 A;  4FOV A;  4X4A A;  2YA7 A;  3K36 A;  1V0F A;  4K3Y A;  1MS5 A;  2HTW A;  1IVD A;  2QWJ A;  5NN9 A;  2W5N A;  4XYX A;  1E8V A;  3B69 A;  1F8B A;  3O9K A;  1NCC N;  3T1E A;  1NMA N;  1NSB A;  2F11 A;  2QWD A;  3B7E A;  2F27 A;  4J9T A;  2HTQ A;  4QN3 A;  4CPN A;  2HTV A;  2W20 A;  1NMB N;  4DGR A;  3SIL A;  4XJR A;  4B7N A;  4XJZ A;  2HT7 A;  3TIC A;  2H2N A;  4FQ4 A;  1MS3 A;  4GZX A;  2XZK A;  1Z4X A;  1MWE A;  4FPE A;  2F24 A;  3H73 A;  5HUG A;  3H6J A;  4GDJ A;  4SLI A;  1EUS A;  1V3C A;  3TIA A;  1NSD A;  1V0Z A;  1N1S A;  3PJQ A;  7NN9 A;  3TI5 A;  3A71 A;  4QN7 A;  3SAN A;  5JYY A;  2F28 A;  3O9J A;  1W0O A;  2QWB A;  4CPO A;  4YZ5 A;  2F0Z A;  2HTY A;  3TI3 A;  1Z4V A;  4UF7 A;  4FPF A;  1NNA A;  4GEZ A;  4MJU A;  4XOG A;  2AH2 A;  4FPY A;  3JU4 A;  2QWA A;  4X47 A;  2X9M A;  1VCJ A;  4MWL A;  3D11 A;  4MZA A;  4XIO A;  2BZD A;  2QWE A;  1SNT A;  2W38 A;  4XE9 A;  2F29 A;  1INV A;  1V3D A;  2HT5 A;  4GZQ A;  1W8N A;  4FP2 A;  2QWC A;  1NCB N;  4NC5 A;  4KS1 A;  1Z4W A;  3CL0 A;  4YW5 A;  2F10 A;  2VK6 A;  2SLI A;  2CML A;  4BBW A;  4YZ4 A;  4MWY A;  4H53 A;  4FOQ A;  4HZV A;  3K38 A;  1W1X A;  2VVZ A;  1S1D A;  1INW A;  3D12 A;  1F8C A;  3A72 A;  4YW3 A;  2QWH A;  5HUN A;  3GVJ A;  3K3A A;  4MWR A;  1SLI A;  4FPC A;  1USR A;  3TI6 A;  1INF A;  1IVF A;  2B8H A;  5HUM A;  4XJ8 A;  2JKB A;  4YW2 A;  4FPH A;  4WEG A;  4FPG A;  3BEQ A;  5B2D A;  2C4L A;  1E8T A;  4NN9 A;  4GB1 A;  1N1Y A;  4QNP A;  2YDP A;  4B7M A;  2QWI A;  1V3B A;  1INY A;  4FPO B;  4Q6K A;  3CKZ A;  2VK7 A;  4HIZ A;  1WCS A;  1NN2 A;  4K1I A;  5B2C A;  4MWU A;  4B7Q A;  1MS8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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