2RJRA

Substrate mimic bound to sgtam
Total Genus 209
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
209
sequence length
526
structure length
525
Chain Sequence
PVSVDGETLTVEAVRRVAEERATVDVPAESIAKAQKSREIFEGIAEQNIPIYGVTTGYGEMIYMQVDKSKEVELQTNLVRSHSAGVGPLFAEDEARAIVAARLNTLAKGHSAVRPIILERLAQYLNEGITPAIPEIGSLGDLAPLSHVASTLIGEGYVLRDGRPVETAQVLAERGIEPLELRFKEGLALINGTSGMTGLGSLVVGRALEQAQQAEIVTALLIEAVRGSTSPFLAEGHDIARPHEGQIDTAANMRALMRGSGLTVEHADLRRELQKDKEAGKDVQRSEIYLQKAYSLRAIPQVVGAVRDTLYHARHKLRIELNSANDNPLFFEGKEIFHGANFHGQPIAFAMDFVTIALTQLGVLAERQINRVLNRHLSYGLPEFLVSGDPGLHSGFAGAQYPATALVAENRTIGPASTQSVPSNGDNQDVVSMGLISARNARRVLSNNNKILAVEYLAAAQAVDISGRFDGLSPAAKATYEAVRRLVPTLGVDRYMADDIELVADALSRGEFLRAIARETDIQLR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design and characterization of mechanism-based inhibitors for the tyrosine aminomutase SgTAM.
pubmed doi rcsb
source organism Streptomyces globisporus
molecule tags Isomerase
molecule keywords Tyrosine aminomutase
total genus 209
structure length 525
sequence length 526
chains with identical sequence B
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2007-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2rjrA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2rjrA02
4BABA 4ADMA 3RD8A 3NZ4A 1C3UA 1U16A 4APBA 1FURA 2NYNA 1VDKA 4HGVA 3GZHA 5D6BA 5HW2A 4C5UA 2RJSA 1K62A 4NSLA 1GK3A 2O7BA 1TJWA 2RJRA 2O6YA 4NLEA 2QGAB 2J91A 4C5RA 4V2QA 1HY1A 4BAAA 1W27A 1YFMA 3RRPA 4FLCA 1FUQA 1AUWA 2O7EA 5EYVA 3C8TA 1K7WA 1TJ7A 1XWOA 3R6VA 1C3CA 1FUOA 2NYFA 3KDYA 1GKMA 4EFCA 1TJVA 3R6YA 2HVGA 1RE5A 4EEIA 3OCEA 2QVEA 3TV2A 3E04A 2PTQA 4C5SA 2X75A 2FUSA 1HY0A 3NO9A 2O7DA 1TJUA 2OHYA 1EB4A 1DCNA 1J3UA 3UNVA 3CZOA 4APAA 3BHGA 4FFXA 1B8FA 4CQ5A 3QBPA 1KQ7A 1GKJA 5EYTA 2YIIA 1U15A 3GTDA 1Q5NA 1YFEA 1T6PA 3KDZA 3OCFA 2VD6A 1DOFA 1JSWA 2O78A 5F91A 1T6JA 1Y2MA 5F92A 2PTSA 4MX2A 1GK2A 3R6QA 1I0AA 2O7FA 2PFMA 4C6GA 4ADLA 2PTRA 2E9FA 4V2RA 1YISA 1FUPA
chains in the Genus database with same CATH superfamily
4BABA 4ADMA 5H8WA 3RD8A 3NZ4A 2FELA 1C3UA 1U16A 4APBA 1FURA 2NYNA 1VDKA 1XMCA 4HGVA 3GZHA 5D6BA 5HW2A 4C5UA 2RJSA 1K62A 4NSLA 1GK3A 5M0JA 2O7BA 1TJWA 2RJRA 2O6YA 4NLEA 1XLYA 2QGAB 2J91A 4WNLA 2VSFA 4C5RA 2FENA 4V2QA 1HY1A 4BAAA 1W27A 1YFMA 3RRPA 4FLCA 1FUQA 1AUWA 2O7EA 5EYVA 3C8TA 1K7WA 1TJ7A 1XWOA 3R6VA 1C3CA 1FUOA 2NYFA 3KDYA 1GKMA 4EFCA 1TJVA 3R6YA 2HVGA 1RE5A 5M0IA 4EEIA 3OCEA 2QVEA 3TV2A 3E04A 2PTQA 4C5SA 2X75A 2FUSA 1HY0A 3NO9A 2O7DA 4A15A 3CRVA 1TJUA 2OHYA 1EB4A 1DCNA 1J3UA 3UNVA 3CZOA 4APAA 1XL7A 3BHGA 4FFXA 1B8FA 4CQ5A 3QBPA 1KQ7A 1GKJA 5EYTA 3GTDA 1U15A 2YIIA 1Q5NA 1YFEA 1T6PA 3KDZA 3OCFA 1XL8A 2VD6A 1DOFA 1JSWA 2O78A 2VL7A 5F91A 1T6JA 1Y2MA 5F92A 2PTSA 4MX2A 1GK2A 3R6QA 1I0AA 2O7FA 2PFMA 4C6GA 1XMDA 4ADLA 2PTRA 2E9FA 4V2RA 3CRW1 1YISA 1FUPA
chains in the Genus database with same CATH topology
4BABA 4ADMA 3RD8A 3NZ4A 1C3UA 1U16A 4APBA 1FURA 2NYNA 1VDKA 4HGVA 3GZHA 5D6BA 5HW2A 4C5UA 2RJSA 1K62A 4NSLA 1GK3A 2O7BA 1TJWA 2RJRA 2O6YA 4NLEA 2QGAB 2J91A 4C5RA 4V2QA 1HY1A 4BAAA 1W27A 1YFMA 3RRPA 4FLCA 1FUQA 1AUWA 2O7EA 5EYVA 3C8TA 1K7WA 1TJ7A 1XWOA 3R6VA 1C3CA 1FUOA 2NYFA 3KDYA 1GKMA 4EFCA 1TJVA 3R6YA 2HVGA 1RE5A 4EEIA 3OCEA 2QVEA 3TV2A 3E04A 2PTQA 4C5SA 2X75A 2FUSA 1HY0A 3NO9A 2O7DA 1TJUA 2OHYA 1EB4A 1DCNA 1J3UA 3UNVA 3CZOA 4APAA 3BHGA 4FFXA 1B8FA 4CQ5A 3QBPA 1KQ7A 1GKJA 5EYTA 2YIIA 1U15A 3GTDA 1Q5NA 1YFEA 1T6PA 3KDZA 3OCFA 2VD6A 1DOFA 1JSWA 2O78A 5F91A 1T6JA 1Y2MA 5F92A 2PTSA 4MX2A 1GK2A 3R6QA 1I0AA 2O7FA 2PFMA 4C6GA 4ADLA 2PTRA 2E9FA 4V2RA 1YISA 1FUPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BAB A;  4ADM A;  3RD8 A;  3NZ4 A;  1C3U A;  1U16 A;  4APB A;  1FUR A;  2NYN A;  1VDK A;  4HGV A;  3GZH A;  5D6B A;  5HW2 A;  4C5U A;  2RJS A;  1K62 A;  4NSL A;  1GK3 A;  2O7B A;  1TJW A;  2RJR A;  2O6Y A;  4NLE A;  2QGA B;  2J91 A;  4C5R A;  4V2Q A;  1HY1 A;  4BAA A;  1W27 A;  1YFM A;  3RRP A;  4FLC A;  1FUQ A;  1AUW A;  2O7E A;  5EYV A;  3C8T A;  1K7W A;  1TJ7 A;  1XWO A;  3R6V A;  1C3C A;  1FUO A;  2NYF A;  3KDY A;  1GKM A;  4EFC A;  1TJV A;  3R6Y A;  2HVG A;  1RE5 A;  4EEI A;  3OCE A;  2QVE A;  3TV2 A;  3E04 A;  2PTQ A;  4C5S A;  2X75 A;  2FUS A;  1HY0 A;  3NO9 A;  2O7D A;  1TJU A;  2OHY A;  1EB4 A;  1DCN A;  1J3U A;  3UNV A;  3CZO A;  4APA A;  3BHG A;  4FFX A;  1B8F A;  4CQ5 A;  3QBP A;  1KQ7 A;  1GKJ A;  5EYT A;  2YII A;  1U15 A;  3GTD A;  1Q5N A;  1YFE A;  1T6P A;  3KDZ A;  3OCF A;  2VD6 A;  1DOF A;  1JSW A;  2O78 A;  5F91 A;  1T6J A;  1Y2M A;  5F92 A;  2PTS A;  4MX2 A;  1GK2 A;  3R6Q A;  1I0A A;  2O7F A;  2PFM A;  4C6G A;  4ADL A;  2PTR A;  2E9F A;  4V2R A;  1YIS A;  1FUP A; 
#chains in the Genus database with same CATH topology
 4BAB A;  4ADM A;  5H8W A;  3RD8 A;  3NZ4 A;  2FEL A;  1C3U A;  1U16 A;  4APB A;  1FUR A;  2NYN A;  1VDK A;  1XMC A;  4HGV A;  3GZH A;  5D6B A;  5HW2 A;  4C5U A;  2RJS A;  1K62 A;  4NSL A;  1GK3 A;  5M0J A;  2O7B A;  1TJW A;  2RJR A;  2O6Y A;  4NLE A;  1XLY A;  2QGA B;  2J91 A;  4WNL A;  2VSF A;  4C5R A;  2FEN A;  4V2Q A;  1HY1 A;  4BAA A;  1W27 A;  1YFM A;  3RRP A;  4FLC A;  1FUQ A;  1AUW A;  2O7E A;  5EYV A;  3C8T A;  1K7W A;  1TJ7 A;  1XWO A;  3R6V A;  1C3C A;  1FUO A;  2NYF A;  3KDY A;  1GKM A;  4EFC A;  1TJV A;  3R6Y A;  2HVG A;  1RE5 A;  5M0I A;  4EEI A;  3OCE A;  2QVE A;  3TV2 A;  3E04 A;  2PTQ A;  4C5S A;  2X75 A;  2FUS A;  1HY0 A;  3NO9 A;  2O7D A;  4A15 A;  3CRV A;  1TJU A;  2OHY A;  1EB4 A;  1DCN A;  1J3U A;  3UNV A;  3CZO A;  4APA A;  1XL7 A;  3BHG A;  4FFX A;  1B8F A;  4CQ5 A;  3QBP A;  1KQ7 A;  1GKJ A;  5EYT A;  3GTD A;  1U15 A;  2YII A;  1Q5N A;  1YFE A;  1T6P A;  3KDZ A;  3OCF A;  1XL8 A;  2VD6 A;  1DOF A;  1JSW A;  2O78 A;  2VL7 A;  5F91 A;  1T6J A;  1Y2M A;  5F92 A;  2PTS A;  4MX2 A;  1GK2 A;  3R6Q A;  1I0A A;  2O7F A;  2PFM A;  4C6G A;  1XMD A;  4ADL A;  2PTR A;  2E9F A;  4V2R A;  3CRW 1;  1YIS A;  1FUP A; 
#chains in the Genus database with same CATH homology
 4BAB A;  4ADM A;  3RD8 A;  3NZ4 A;  1C3U A;  1U16 A;  4APB A;  1FUR A;  2NYN A;  1VDK A;  4HGV A;  3GZH A;  5D6B A;  5HW2 A;  4C5U A;  2RJS A;  1K62 A;  4NSL A;  1GK3 A;  2O7B A;  1TJW A;  2RJR A;  2O6Y A;  4NLE A;  2QGA B;  2J91 A;  4C5R A;  4V2Q A;  1HY1 A;  4BAA A;  1W27 A;  1YFM A;  3RRP A;  4FLC A;  1FUQ A;  1AUW A;  2O7E A;  5EYV A;  3C8T A;  1K7W A;  1TJ7 A;  1XWO A;  3R6V A;  1C3C A;  1FUO A;  2NYF A;  3KDY A;  1GKM A;  4EFC A;  1TJV A;  3R6Y A;  2HVG A;  1RE5 A;  4EEI A;  3OCE A;  2QVE A;  3TV2 A;  3E04 A;  2PTQ A;  4C5S A;  2X75 A;  2FUS A;  1HY0 A;  3NO9 A;  2O7D A;  1TJU A;  2OHY A;  1EB4 A;  1DCN A;  1J3U A;  3UNV A;  3CZO A;  4APA A;  3BHG A;  4FFX A;  1B8F A;  4CQ5 A;  3QBP A;  1KQ7 A;  1GKJ A;  5EYT A;  2YII A;  1U15 A;  3GTD A;  1Q5N A;  1YFE A;  1T6P A;  3KDZ A;  3OCF A;  2VD6 A;  1DOF A;  1JSW A;  2O78 A;  5F91 A;  1T6J A;  1Y2M A;  5F92 A;  2PTS A;  4MX2 A;  1GK2 A;  3R6Q A;  1I0A A;  2O7F A;  2PFM A;  4C6G A;  4ADL A;  2PTR A;  2E9F A;  4V2R A;  1YIS A;  1FUP A; 
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