2RJRA

Substrate mimic bound to sgtam
Total Genus 209
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
209
sequence length
526
structure length
525
Chain Sequence
PVSVDGETLTVEAVRRVAEERATVDVPAESIAKAQKSREIFEGIAEQNIPIYGVTTGYGEMIYMQVDKSKEVELQTNLVRSHSAGVGPLFAEDEARAIVAARLNTLAKGHSAVRPIILERLAQYLNEGITPAIPEIGSLGDLAPLSHVASTLIGEGYVLRDGRPVETAQVLAERGIEPLELRFKEGLALINGTSGMTGLGSLVVGRALEQAQQAEIVTALLIEAVRGSTSPFLAEGHDIARPHEGQIDTAANMRALMRGSGLTVEHADLRRELQKDKEAGKDVQRSEIYLQKAYSLRAIPQVVGAVRDTLYHARHKLRIELNSANDNPLFFEGKEIFHGANFHGQPIAFAMDFVTIALTQLGVLAERQINRVLNRHLSYGLPEFLVSGDPGLHSGFAGAQYPATALVAENRTIGPASTQSVPSNGDNQDVVSMGLISARNARRVLSNNNKILAVEYLAAAQAVDISGRFDGLSPAAKATYEAVRRLVPTLGVDRYMADDIELVADALSRGEFLRAIARETDIQLR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design and characterization of mechanism-based inhibitors for the tyrosine aminomutase SgTAM.
pubmed doi rcsb
source organism Streptomyces globisporus
molecule tags Isomerase
molecule keywords Tyrosine aminomutase
total genus 209
structure length 525
sequence length 526
chains with identical sequence B
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2007-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2rjrA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2rjrA02
1KQ7A 5EYTA 1FURA 3GTDA 1TJUA 1TJWA 2HVGA 1AUWA 4ADLA 1FUPA 4C5SA 1XWOA 1HY0A 2PTQA 1DOFA 1FUQA 3NO9A 5EYVA 1GK3A 2OHYA 1T6PA 1TJVA 3R6QA 3E04A 5HW2A 3OCFA 1VDKA 2E9FA 4NLEA 2RJSA 2O7FA 1DCNA 1K62A 1TJ7A 3QBPA 4ADMA 1RE5A 3KDYA 2PTRA 4NSLA 2O7BA 3OCEA 1U16A 4BAAA 1B8FA 1GKJA 1J3UA 2PFMA 1W27A 2J91A 4MX2A 2RJRA 5F91A 4HGVA 4C5UA 3TV2A 1K7WA 3C8TA 3UNVA 1Y2MA 4V2QA 2PTSA 3RD8A 3BHGA 2FUSA 3KDZA 1YFMA 2NYFA 4EEIA 2QVEA 1C3CA 1U15A 1GK2A 1GKMA 4C5RA 1C3UA 4C6GA 2QGAB 4APAA 1YFEA 3RRPA 4FFXA 3R6VA 2O78A 5F92A 3R6YA 2O7EA 1Q5NA 1FUOA 5D6BA 1YISA 2X75A 4V2RA 4CQ5A 3NZ4A 1I0AA 4FLCA 1EB4A 2VD6A 3CZOA 2NYNA 1T6JA 1JSWA 2O6YA 4BABA 2O7DA 4EFCA 2YIIA 1HY1A 3GZHA 4APBA
chains in the Genus database with same CATH superfamily
1KQ7A 5EYTA 1FURA 3GTDA 1TJUA 5M0JA 1TJWA 2HVGA 1AUWA 4ADLA 1XLYA 1FUPA 4C5SA 3CRW1 1XWOA 5H8WA 1HY0A 2PTQA 1DOFA 1FUQA 3NO9A 1XL8A 5EYVA 1GK3A 2FENA 2OHYA 1T6PA 1TJVA 3R6QA 2VSFA 3E04A 5HW2A 3OCFA 1VDKA 2E9FA 4NLEA 2RJSA 2O7FA 1DCNA 1K62A 1TJ7A 3QBPA 4ADMA 4WNLA 1RE5A 1XL7A 3KDYA 1XMCA 2PTRA 4NSLA 2O7BA 3OCEA 1U16A 4BAAA 1B8FA 1GKJA 1J3UA 2PFMA 1W27A 2J91A 4MX2A 2RJRA 5F91A 2VL7A 4HGVA 4C5UA 3TV2A 1K7WA 3C8TA 3UNVA 1Y2MA 4V2QA 2PTSA 3RD8A 3BHGA 2FUSA 3KDZA 1YFMA 2NYFA 4EEIA 2QVEA 1C3CA 1U15A 1GK2A 1GKMA 4C5RA 1C3UA 5M0IA 4C6GA 2QGAB 4APAA 1YFEA 3RRPA 4FFXA 3R6VA 2FELA 2O78A 5F92A 3CRVA 3R6YA 2O7EA 1Q5NA 4A15A 1FUOA 5D6BA 1YISA 2X75A 4V2RA 4CQ5A 3NZ4A 1I0AA 4FLCA 1EB4A 2VD6A 3CZOA 2NYNA 1T6JA 1JSWA 2O6YA 4BABA 2O7DA 4EFCA 2YIIA 1HY1A 3GZHA 4APBA 1XMDA
chains in the Genus database with same CATH topology
1KQ7A 5EYTA 1FURA 3GTDA 1TJUA 1TJWA 2HVGA 1AUWA 4ADLA 1FUPA 4C5SA 1XWOA 1HY0A 2PTQA 1DOFA 1FUQA 3NO9A 5EYVA 1GK3A 2OHYA 1T6PA 1TJVA 3R6QA 3E04A 5HW2A 3OCFA 1VDKA 2E9FA 4NLEA 2RJSA 2O7FA 1DCNA 1K62A 1TJ7A 3QBPA 4ADMA 1RE5A 3KDYA 2PTRA 4NSLA 2O7BA 3OCEA 1U16A 4BAAA 1B8FA 1GKJA 1J3UA 2PFMA 1W27A 2J91A 4MX2A 2RJRA 5F91A 4HGVA 4C5UA 3TV2A 1K7WA 3C8TA 3UNVA 1Y2MA 4V2QA 2PTSA 3RD8A 3BHGA 2FUSA 3KDZA 1YFMA 2NYFA 4EEIA 2QVEA 1C3CA 1U15A 1GK2A 1GKMA 4C5RA 1C3UA 4C6GA 2QGAB 4APAA 1YFEA 3RRPA 4FFXA 3R6VA 2O78A 5F92A 3R6YA 2O7EA 1Q5NA 1FUOA 5D6BA 1YISA 2X75A 4V2RA 4CQ5A 3NZ4A 1I0AA 4FLCA 1EB4A 2VD6A 3CZOA 2NYNA 1T6JA 1JSWA 2O6YA 4BABA 2O7DA 4EFCA 2YIIA 1HY1A 3GZHA 4APBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KQ7 A;  5EYT A;  1FUR A;  3GTD A;  1TJU A;  1TJW A;  2HVG A;  1AUW A;  4ADL A;  1FUP A;  4C5S A;  1XWO A;  1HY0 A;  2PTQ A;  1DOF A;  1FUQ A;  3NO9 A;  5EYV A;  1GK3 A;  2OHY A;  1T6P A;  1TJV A;  3R6Q A;  3E04 A;  5HW2 A;  3OCF A;  1VDK A;  2E9F A;  4NLE A;  2RJS A;  2O7F A;  1DCN A;  1K62 A;  1TJ7 A;  3QBP A;  4ADM A;  1RE5 A;  3KDY A;  2PTR A;  4NSL A;  2O7B A;  3OCE A;  1U16 A;  4BAA A;  1B8F A;  1GKJ A;  1J3U A;  2PFM A;  1W27 A;  2J91 A;  4MX2 A;  2RJR A;  5F91 A;  4HGV A;  4C5U A;  3TV2 A;  1K7W A;  3C8T A;  3UNV A;  1Y2M A;  4V2Q A;  2PTS A;  3RD8 A;  3BHG A;  2FUS A;  3KDZ A;  1YFM A;  2NYF A;  4EEI A;  2QVE A;  1C3C A;  1U15 A;  1GK2 A;  1GKM A;  4C5R A;  1C3U A;  4C6G A;  2QGA B;  4APA A;  1YFE A;  3RRP A;  4FFX A;  3R6V A;  2O78 A;  5F92 A;  3R6Y A;  2O7E A;  1Q5N A;  1FUO A;  5D6B A;  1YIS A;  2X75 A;  4V2R A;  4CQ5 A;  3NZ4 A;  1I0A A;  4FLC A;  1EB4 A;  2VD6 A;  3CZO A;  2NYN A;  1T6J A;  1JSW A;  2O6Y A;  4BAB A;  2O7D A;  4EFC A;  2YII A;  1HY1 A;  3GZH A;  4APB A; 
#chains in the Genus database with same CATH topology
 1KQ7 A;  5EYT A;  1FUR A;  3GTD A;  1TJU A;  5M0J A;  1TJW A;  2HVG A;  1AUW A;  4ADL A;  1XLY A;  1FUP A;  4C5S A;  3CRW 1;  1XWO A;  5H8W A;  1HY0 A;  2PTQ A;  1DOF A;  1FUQ A;  3NO9 A;  1XL8 A;  5EYV A;  1GK3 A;  2FEN A;  2OHY A;  1T6P A;  1TJV A;  3R6Q A;  2VSF A;  3E04 A;  5HW2 A;  3OCF A;  1VDK A;  2E9F A;  4NLE A;  2RJS A;  2O7F A;  1DCN A;  1K62 A;  1TJ7 A;  3QBP A;  4ADM A;  4WNL A;  1RE5 A;  1XL7 A;  3KDY A;  1XMC A;  2PTR A;  4NSL A;  2O7B A;  3OCE A;  1U16 A;  4BAA A;  1B8F A;  1GKJ A;  1J3U A;  2PFM A;  1W27 A;  2J91 A;  4MX2 A;  2RJR A;  5F91 A;  2VL7 A;  4HGV A;  4C5U A;  3TV2 A;  1K7W A;  3C8T A;  3UNV A;  1Y2M A;  4V2Q A;  2PTS A;  3RD8 A;  3BHG A;  2FUS A;  3KDZ A;  1YFM A;  2NYF A;  4EEI A;  2QVE A;  1C3C A;  1U15 A;  1GK2 A;  1GKM A;  4C5R A;  1C3U A;  5M0I A;  4C6G A;  2QGA B;  4APA A;  1YFE A;  3RRP A;  4FFX A;  3R6V A;  2FEL A;  2O78 A;  5F92 A;  3CRV A;  3R6Y A;  2O7E A;  1Q5N A;  4A15 A;  1FUO A;  5D6B A;  1YIS A;  2X75 A;  4V2R A;  4CQ5 A;  3NZ4 A;  1I0A A;  4FLC A;  1EB4 A;  2VD6 A;  3CZO A;  2NYN A;  1T6J A;  1JSW A;  2O6Y A;  4BAB A;  2O7D A;  4EFC A;  2YII A;  1HY1 A;  3GZH A;  4APB A;  1XMD A; 
#chains in the Genus database with same CATH homology
 1KQ7 A;  5EYT A;  1FUR A;  3GTD A;  1TJU A;  1TJW A;  2HVG A;  1AUW A;  4ADL A;  1FUP A;  4C5S A;  1XWO A;  1HY0 A;  2PTQ A;  1DOF A;  1FUQ A;  3NO9 A;  5EYV A;  1GK3 A;  2OHY A;  1T6P A;  1TJV A;  3R6Q A;  3E04 A;  5HW2 A;  3OCF A;  1VDK A;  2E9F A;  4NLE A;  2RJS A;  2O7F A;  1DCN A;  1K62 A;  1TJ7 A;  3QBP A;  4ADM A;  1RE5 A;  3KDY A;  2PTR A;  4NSL A;  2O7B A;  3OCE A;  1U16 A;  4BAA A;  1B8F A;  1GKJ A;  1J3U A;  2PFM A;  1W27 A;  2J91 A;  4MX2 A;  2RJR A;  5F91 A;  4HGV A;  4C5U A;  3TV2 A;  1K7W A;  3C8T A;  3UNV A;  1Y2M A;  4V2Q A;  2PTS A;  3RD8 A;  3BHG A;  2FUS A;  3KDZ A;  1YFM A;  2NYF A;  4EEI A;  2QVE A;  1C3C A;  1U15 A;  1GK2 A;  1GKM A;  4C5R A;  1C3U A;  4C6G A;  2QGA B;  4APA A;  1YFE A;  3RRP A;  4FFX A;  3R6V A;  2O78 A;  5F92 A;  3R6Y A;  2O7E A;  1Q5N A;  1FUO A;  5D6B A;  1YIS A;  2X75 A;  4V2R A;  4CQ5 A;  3NZ4 A;  1I0A A;  4FLC A;  1EB4 A;  2VD6 A;  3CZO A;  2NYN A;  1T6J A;  1JSW A;  2O6Y A;  4BAB A;  2O7D A;  4EFC A;  2YII A;  1HY1 A;  3GZH A;  4APB A; 
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