2RJRA

Substrate mimic bound to sgtam
Total Genus 209
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
209
sequence length
526
structure length
525
Chain Sequence
b'PVSVDGETLTVEAVRRVAEERATVDVPAESIAKAQKSREIFEGIAEQNIPIYGVTTGYGEMIYMQVDKSKEVELQTNLVRSHSAGVGPLFAEDEARAIVAARLNTLAKGHSAVRPIILERLAQYLNEGITPAIPEIGSLGDLAPLSHVASTLIGEGYVLRDGRPVETAQVLAERGIEPLELRFKEGLALINGTSGMTGLGSLVVGRALEQAQQAEIVTALLIEAVRGSTSPFLAEGHDIARPHEGQIDTAANMRALMRGSGLTVEHADLRRELQKDKEAGKDVQRSEIYLQKAYSLRAIPQVVGAVRDTLYHARHKLRIELNSANDNPLFFEGKEIFHGANFHGQPIAFAMDFVTIALTQLGVLAERQINRVLNRHLSYGLPEFLVSGDPGLHSGFAGAQYPATALVAENRTIGPASTQSVPSNGDNQDVVSMGLISARNARRVLSNNNKILAVEYLAAAQAVDISGRFDGLSPAAKATYEAVRRLVPTLGVDRYMADDIELVADALSRGEFLRAIARETDIQLR'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Tyrosine aminomutase
publication title Design and characterization of mechanism-based inhibitors for the tyrosine aminomutase SgTAM.
pubmed doi rcsb
source organism Streptomyces globisporus
molecule tags Isomerase
total genus 209
structure length 525
sequence length 526
chains with identical sequence B
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2007-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2rjrA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2rjrA02
3R6YA 2O7FA 1Y2MA 2RJRA 3UNVA 1U16A 4BABA 3RRPA 1KQ7A 5EYVA 2O7BA 3KDZA 4NSLA 1EB4A 1GK3A 1T6JA 3OCFA 2QVEA 1GK2A 2O7DA 3GTDA 4FFXA 1T6PA 1TJWA 3QBPA 2O78A 4ADMA 3NZ4A 2OHYA 2PTQA 4EEIA 1YFMA 4C6GA 2HVGA 3KDYA 4APBA 1W27A 2RJSA 5F92A 2YIIA 5F91A 1YISA 4C5UA 1B8FA 1K7WA 4C5SA 1Q5NA 2NYFA 4HGVA 3BHGA 1TJ7A 1I0AA 1J3UA 2O6YA 5HW2A 1RE5A 4V2RA 4C5RA 5D6BA 2E9FA 1GKJA 4BAAA 1XWOA 4V2QA 1VDKA 4CQ5A 3GZHA 4NLEA 2VD6A 1FUQA 3R6QA 3RD8A 4EFCA 3NO9A 1FURA 3OCEA 3CZOA 1YFEA 3E04A 2FUSA 1DCNA 2NYNA 1DOFA 2PTRA 1TJVA 4APAA 1AUWA 1GKMA 1C3UA 4ADLA 1K62A 1TJUA 1FUPA 1JSWA 2O7EA 3R6VA 4MX2A 2QGAB 1C3CA 1U15A 1HY1A 1HY0A 1FUOA 5EYTA 4FLCA 2PTSA 2X75A 3C8TA 2J91A 3TV2A 2PFMA
chains in the Genus database with same CATH superfamily
3R6YA 2O7FA 5M0IA 1Y2MA 2RJRA 3UNVA 1U16A 4BABA 3RRPA 1KQ7A 5EYVA 1XL7A 2O7BA 3KDZA 4NSLA 1EB4A 1GK3A 1XLYA 1T6JA 3OCFA 2QVEA 1GK2A 2O7DA 3GTDA 4FFXA 1T6PA 1TJWA 3QBPA 2O78A 4ADMA 3NZ4A 2OHYA 2PTQA 4EEIA 1YFMA 4C6GA 2HVGA 3KDYA 3CRW1 4APBA 1W27A 2RJSA 5F92A 4WNLA 4A15A 2YIIA 5F91A 1YISA 4C5UA 1B8FA 1K7WA 4C5SA 1Q5NA 2NYFA 4HGVA 3BHGA 1TJ7A 1I0AA 1J3UA 2O6YA 5HW2A 1RE5A 4V2RA 4C5RA 2FELA 5D6BA 2E9FA 1GKJA 4BAAA 1XWOA 4V2QA 1XL8A 1VDKA 4CQ5A 3GZHA 4NLEA 2VD6A 1FUQA 3R6QA 3RD8A 4EFCA 5M0JA 3NO9A 1FURA 3OCEA 3CZOA 1YFEA 3E04A 2FUSA 1XMDA 1DCNA 2NYNA 1DOFA 2PTRA 1XMCA 3CRVA 1TJVA 4APAA 1AUWA 1GKMA 1C3UA 4ADLA 1K62A 1TJUA 1FUPA 1JSWA 2O7EA 3R6VA 4MX2A 2QGAB 1C3CA 1U15A 2VSFA 5H8WA 1HY1A 1HY0A 1FUOA 5EYTA 2VL7A 4FLCA 2PTSA 2X75A 3C8TA 2J91A 3TV2A 2PFMA 2FENA
chains in the Genus database with same CATH topology
3R6YA 2O7FA 1Y2MA 2RJRA 3UNVA 1U16A 4BABA 3RRPA 1KQ7A 5EYVA 2O7BA 3KDZA 4NSLA 1EB4A 1GK3A 1T6JA 3OCFA 2QVEA 1GK2A 2O7DA 3GTDA 4FFXA 1T6PA 1TJWA 3QBPA 2O78A 4ADMA 3NZ4A 2OHYA 2PTQA 4EEIA 1YFMA 4C6GA 2HVGA 3KDYA 4APBA 1W27A 2RJSA 5F92A 2YIIA 5F91A 1YISA 4C5UA 1B8FA 1K7WA 4C5SA 1Q5NA 2NYFA 4HGVA 3BHGA 1TJ7A 1I0AA 1J3UA 2O6YA 5HW2A 1RE5A 4V2RA 4C5RA 5D6BA 2E9FA 1GKJA 4BAAA 1XWOA 4V2QA 1VDKA 4CQ5A 3GZHA 4NLEA 2VD6A 1FUQA 3R6QA 3RD8A 4EFCA 3NO9A 1FURA 3OCEA 3CZOA 1YFEA 3E04A 2FUSA 1DCNA 2NYNA 1DOFA 2PTRA 1TJVA 4APAA 1AUWA 1GKMA 1C3UA 4ADLA 1K62A 1TJUA 1FUPA 1JSWA 2O7EA 3R6VA 4MX2A 2QGAB 1C3CA 1U15A 1HY1A 1HY0A 1FUOA 5EYTA 4FLCA 2PTSA 2X75A 3C8TA 2J91A 3TV2A 2PFMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3R6Y A;  2O7F A;  1Y2M A;  2RJR A;  3UNV A;  1U16 A;  4BAB A;  3RRP A;  1KQ7 A;  5EYV A;  2O7B A;  3KDZ A;  4NSL A;  1EB4 A;  1GK3 A;  1T6J A;  3OCF A;  2QVE A;  1GK2 A;  2O7D A;  3GTD A;  4FFX A;  1T6P A;  1TJW A;  3QBP A;  2O78 A;  4ADM A;  3NZ4 A;  2OHY A;  2PTQ A;  4EEI A;  1YFM A;  4C6G A;  2HVG A;  3KDY A;  4APB A;  1W27 A;  2RJS A;  5F92 A;  2YII A;  5F91 A;  1YIS A;  4C5U A;  1B8F A;  1K7W A;  4C5S A;  1Q5N A;  2NYF A;  4HGV A;  3BHG A;  1TJ7 A;  1I0A A;  1J3U A;  2O6Y A;  5HW2 A;  1RE5 A;  4V2R A;  4C5R A;  5D6B A;  2E9F A;  1GKJ A;  4BAA A;  1XWO A;  4V2Q A;  1VDK A;  4CQ5 A;  3GZH A;  4NLE A;  2VD6 A;  1FUQ A;  3R6Q A;  3RD8 A;  4EFC A;  3NO9 A;  1FUR A;  3OCE A;  3CZO A;  1YFE A;  3E04 A;  2FUS A;  1DCN A;  2NYN A;  1DOF A;  2PTR A;  1TJV A;  4APA A;  1AUW A;  1GKM A;  1C3U A;  4ADL A;  1K62 A;  1TJU A;  1FUP A;  1JSW A;  2O7E A;  3R6V A;  4MX2 A;  2QGA B;  1C3C A;  1U15 A;  1HY1 A;  1HY0 A;  1FUO A;  5EYT A;  4FLC A;  2PTS A;  2X75 A;  3C8T A;  2J91 A;  3TV2 A;  2PFM A; 
#chains in the Genus database with same CATH topology
 3R6Y A;  2O7F A;  5M0I A;  1Y2M A;  2RJR A;  3UNV A;  1U16 A;  4BAB A;  3RRP A;  1KQ7 A;  5EYV A;  1XL7 A;  2O7B A;  3KDZ A;  4NSL A;  1EB4 A;  1GK3 A;  1XLY A;  1T6J A;  3OCF A;  2QVE A;  1GK2 A;  2O7D A;  3GTD A;  4FFX A;  1T6P A;  1TJW A;  3QBP A;  2O78 A;  4ADM A;  3NZ4 A;  2OHY A;  2PTQ A;  4EEI A;  1YFM A;  4C6G A;  2HVG A;  3KDY A;  3CRW 1;  4APB A;  1W27 A;  2RJS A;  5F92 A;  4WNL A;  4A15 A;  2YII A;  5F91 A;  1YIS A;  4C5U A;  1B8F A;  1K7W A;  4C5S A;  1Q5N A;  2NYF A;  4HGV A;  3BHG A;  1TJ7 A;  1I0A A;  1J3U A;  2O6Y A;  5HW2 A;  1RE5 A;  4V2R A;  4C5R A;  2FEL A;  5D6B A;  2E9F A;  1GKJ A;  4BAA A;  1XWO A;  4V2Q A;  1XL8 A;  1VDK A;  4CQ5 A;  3GZH A;  4NLE A;  2VD6 A;  1FUQ A;  3R6Q A;  3RD8 A;  4EFC A;  5M0J A;  3NO9 A;  1FUR A;  3OCE A;  3CZO A;  1YFE A;  3E04 A;  2FUS A;  1XMD A;  1DCN A;  2NYN A;  1DOF A;  2PTR A;  1XMC A;  3CRV A;  1TJV A;  4APA A;  1AUW A;  1GKM A;  1C3U A;  4ADL A;  1K62 A;  1TJU A;  1FUP A;  1JSW A;  2O7E A;  3R6V A;  4MX2 A;  2QGA B;  1C3C A;  1U15 A;  2VSF A;  5H8W A;  1HY1 A;  1HY0 A;  1FUO A;  5EYT A;  2VL7 A;  4FLC A;  2PTS A;  2X75 A;  3C8T A;  2J91 A;  3TV2 A;  2PFM A;  2FEN A; 
#chains in the Genus database with same CATH homology
 3R6Y A;  2O7F A;  1Y2M A;  2RJR A;  3UNV A;  1U16 A;  4BAB A;  3RRP A;  1KQ7 A;  5EYV A;  2O7B A;  3KDZ A;  4NSL A;  1EB4 A;  1GK3 A;  1T6J A;  3OCF A;  2QVE A;  1GK2 A;  2O7D A;  3GTD A;  4FFX A;  1T6P A;  1TJW A;  3QBP A;  2O78 A;  4ADM A;  3NZ4 A;  2OHY A;  2PTQ A;  4EEI A;  1YFM A;  4C6G A;  2HVG A;  3KDY A;  4APB A;  1W27 A;  2RJS A;  5F92 A;  2YII A;  5F91 A;  1YIS A;  4C5U A;  1B8F A;  1K7W A;  4C5S A;  1Q5N A;  2NYF A;  4HGV A;  3BHG A;  1TJ7 A;  1I0A A;  1J3U A;  2O6Y A;  5HW2 A;  1RE5 A;  4V2R A;  4C5R A;  5D6B A;  2E9F A;  1GKJ A;  4BAA A;  1XWO A;  4V2Q A;  1VDK A;  4CQ5 A;  3GZH A;  4NLE A;  2VD6 A;  1FUQ A;  3R6Q A;  3RD8 A;  4EFC A;  3NO9 A;  1FUR A;  3OCE A;  3CZO A;  1YFE A;  3E04 A;  2FUS A;  1DCN A;  2NYN A;  1DOF A;  2PTR A;  1TJV A;  4APA A;  1AUW A;  1GKM A;  1C3U A;  4ADL A;  1K62 A;  1TJU A;  1FUP A;  1JSW A;  2O7E A;  3R6V A;  4MX2 A;  2QGA B;  1C3C A;  1U15 A;  1HY1 A;  1HY0 A;  1FUO A;  5EYT A;  4FLC A;  2PTS A;  2X75 A;  3C8T A;  2J91 A;  3TV2 A;  2PFM A; 
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