2RJRA

Substrate mimic bound to sgtam
Total Genus 209
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
209
sequence length
526
structure length
525
Chain Sequence
PVSVDGETLTVEAVRRVAEERATVDVPAESIAKAQKSREIFEGIAEQNIPIYGVTTGYGEMIYMQVDKSKEVELQTNLVRSHSAGVGPLFAEDEARAIVAARLNTLAKGHSAVRPIILERLAQYLNEGITPAIPEIGSLGDLAPLSHVASTLIGEGYVLRDGRPVETAQVLAERGIEPLELRFKEGLALINGTSGMTGLGSLVVGRALEQAQQAEIVTALLIEAVRGSTSPFLAEGHDIARPHEGQIDTAANMRALMRGSGLTVEHADLRRELQKDKEAGKDVQRSEIYLQKAYSLRAIPQVVGAVRDTLYHARHKLRIELNSANDNPLFFEGKEIFHGANFHGQPIAFAMDFVTIALTQLGVLAERQINRVLNRHLSYGLPEFLVSGDPGLHSGFAGAQYPATALVAENRTIGPASTQSVPSNGDNQDVVSMGLISARNARRVLSNNNKILAVEYLAAAQAVDISGRFDGLSPAAKATYEAVRRLVPTLGVDRYMADDIELVADALSRGEFLRAIARETDIQLR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Tyrosine aminomutase
publication title Design and characterization of mechanism-based inhibitors for the tyrosine aminomutase SgTAM.
pubmed doi rcsb
source organism Streptomyces globisporus
molecule tags Isomerase
total genus 209
structure length 525
sequence length 526
chains with identical sequence B
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2007-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2rjrA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2rjrA02
5F92A 1B8FA 2J91A 1Y2MA 4C5UA 1W27A 1C3UA 3RD8A 1T6PA 2HVGA 3CZOA 1VDKA 1GK2A 3TV2A 2NYFA 3NZ4A 1C3CA 4NLEA 2O7FA 4APAA 1TJUA 3KDYA 3R6YA 4NSLA 3C8TA 4MX2A 3OCEA 4HGVA 2QGAB 1I0AA 1TJWA 3R6VA 4BABA 2O7BA 2NYNA 2VD6A 5EYVA 5F91A 4C6GA 4BAAA 1YFEA 4EEIA 3QBPA 3BHGA 1K62A 1DCNA 1Q5NA 2QVEA 1FUPA 1JSWA 2E9FA 1AUWA 2FUSA 2RJRA 3R6QA 1U16A 3OCFA 2OHYA 4FFXA 4V2QA 2X75A 5EYTA 2O78A 1FURA 1TJ7A 4C5SA 2PTQA 4EFCA 1FUQA 1T6JA 1GKMA 1XWOA 2PTSA 1RE5A 3NO9A 4ADLA 3GTDA 3E04A 1J3UA 1KQ7A 1K7WA 4V2RA 1HY0A 1DOFA 1YISA 2PTRA 2RJSA 3KDZA 3UNVA 2PFMA 3GZHA 1GK3A 1EB4A 4APBA 4CQ5A 1TJVA 1YFMA 1FUOA 1GKJA 2YIIA 5D6BA 2O7EA 1U15A 4C5RA 5HW2A 4ADMA 1HY1A 2O6YA 4FLCA 2O7DA 3RRPA
chains in the Genus database with same CATH superfamily
5F92A 1B8FA 2J91A 1Y2MA 4C5UA 1W27A 1C3UA 3RD8A 1T6PA 2HVGA 5M0JA 3CZOA 1VDKA 1GK2A 3TV2A 2NYFA 2FENA 3NZ4A 1C3CA 4NLEA 2O7FA 4APAA 1TJUA 3KDYA 2FELA 3R6YA 4NSLA 3C8TA 4MX2A 3OCEA 4HGVA 2QGAB 1I0AA 1TJWA 3R6VA 4BABA 2O7BA 5M0IA 2NYNA 2VD6A 1XMCA 5EYVA 5F91A 4C6GA 4BAAA 1YFEA 4EEIA 3QBPA 3BHGA 1K62A 1DCNA 1XL7A 1Q5NA 2QVEA 1FUPA 1JSWA 2E9FA 1AUWA 2FUSA 2VL7A 2RJRA 3R6QA 1U16A 3OCFA 2OHYA 2VSFA 4FFXA 2X75A 4V2QA 5EYTA 2O78A 1FURA 1XMDA 1TJ7A 4C5SA 2PTQA 4WNLA 4EFCA 1FUQA 3CRW1 1T6JA 1GKMA 1XWOA 2PTSA 1RE5A 1XL8A 3NO9A 4ADLA 3GTDA 3E04A 5H8WA 1J3UA 1KQ7A 1K7WA 4V2RA 1HY0A 1DOFA 1YISA 3CRVA 2PTRA 4A15A 2RJSA 3KDZA 1XLYA 3UNVA 2PFMA 3GZHA 1GK3A 1EB4A 4APBA 4CQ5A 1TJVA 1YFMA 1FUOA 1GKJA 2YIIA 5D6BA 2O7EA 1U15A 4C5RA 5HW2A 4ADMA 1HY1A 2O6YA 4FLCA 2O7DA 3RRPA
chains in the Genus database with same CATH topology
5F92A 1B8FA 2J91A 1Y2MA 4C5UA 1W27A 1C3UA 3RD8A 1T6PA 2HVGA 3CZOA 1VDKA 1GK2A 3TV2A 2NYFA 3NZ4A 1C3CA 4NLEA 2O7FA 4APAA 1TJUA 3KDYA 3R6YA 4NSLA 3C8TA 4MX2A 3OCEA 4HGVA 2QGAB 1I0AA 1TJWA 3R6VA 4BABA 2O7BA 2NYNA 2VD6A 5EYVA 5F91A 4C6GA 4BAAA 1YFEA 4EEIA 3QBPA 3BHGA 1K62A 1DCNA 1Q5NA 2QVEA 1FUPA 1JSWA 2E9FA 1AUWA 2FUSA 2RJRA 3R6QA 1U16A 3OCFA 2OHYA 4FFXA 4V2QA 2X75A 5EYTA 2O78A 1FURA 1TJ7A 4C5SA 2PTQA 4EFCA 1FUQA 1T6JA 1GKMA 1XWOA 2PTSA 1RE5A 3NO9A 4ADLA 3GTDA 3E04A 1J3UA 1KQ7A 1K7WA 4V2RA 1HY0A 1DOFA 1YISA 2PTRA 2RJSA 3KDZA 3UNVA 2PFMA 3GZHA 1GK3A 1EB4A 4APBA 4CQ5A 1TJVA 1YFMA 1FUOA 1GKJA 2YIIA 5D6BA 2O7EA 1U15A 4C5RA 5HW2A 4ADMA 1HY1A 2O6YA 4FLCA 2O7DA 3RRPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5F92 A;  1B8F A;  2J91 A;  1Y2M A;  4C5U A;  1W27 A;  1C3U A;  3RD8 A;  1T6P A;  2HVG A;  3CZO A;  1VDK A;  1GK2 A;  3TV2 A;  2NYF A;  3NZ4 A;  1C3C A;  4NLE A;  2O7F A;  4APA A;  1TJU A;  3KDY A;  3R6Y A;  4NSL A;  3C8T A;  4MX2 A;  3OCE A;  4HGV A;  2QGA B;  1I0A A;  1TJW A;  3R6V A;  4BAB A;  2O7B A;  2NYN A;  2VD6 A;  5EYV A;  5F91 A;  4C6G A;  4BAA A;  1YFE A;  4EEI A;  3QBP A;  3BHG A;  1K62 A;  1DCN A;  1Q5N A;  2QVE A;  1FUP A;  1JSW A;  2E9F A;  1AUW A;  2FUS A;  2RJR A;  3R6Q A;  1U16 A;  3OCF A;  2OHY A;  4FFX A;  4V2Q A;  2X75 A;  5EYT A;  2O78 A;  1FUR A;  1TJ7 A;  4C5S A;  2PTQ A;  4EFC A;  1FUQ A;  1T6J A;  1GKM A;  1XWO A;  2PTS A;  1RE5 A;  3NO9 A;  4ADL A;  3GTD A;  3E04 A;  1J3U A;  1KQ7 A;  1K7W A;  4V2R A;  1HY0 A;  1DOF A;  1YIS A;  2PTR A;  2RJS A;  3KDZ A;  3UNV A;  2PFM A;  3GZH A;  1GK3 A;  1EB4 A;  4APB A;  4CQ5 A;  1TJV A;  1YFM A;  1FUO A;  1GKJ A;  2YII A;  5D6B A;  2O7E A;  1U15 A;  4C5R A;  5HW2 A;  4ADM A;  1HY1 A;  2O6Y A;  4FLC A;  2O7D A;  3RRP A; 
#chains in the Genus database with same CATH topology
 5F92 A;  1B8F A;  2J91 A;  1Y2M A;  4C5U A;  1W27 A;  1C3U A;  3RD8 A;  1T6P A;  2HVG A;  5M0J A;  3CZO A;  1VDK A;  1GK2 A;  3TV2 A;  2NYF A;  2FEN A;  3NZ4 A;  1C3C A;  4NLE A;  2O7F A;  4APA A;  1TJU A;  3KDY A;  2FEL A;  3R6Y A;  4NSL A;  3C8T A;  4MX2 A;  3OCE A;  4HGV A;  2QGA B;  1I0A A;  1TJW A;  3R6V A;  4BAB A;  2O7B A;  5M0I A;  2NYN A;  2VD6 A;  1XMC A;  5EYV A;  5F91 A;  4C6G A;  4BAA A;  1YFE A;  4EEI A;  3QBP A;  3BHG A;  1K62 A;  1DCN A;  1XL7 A;  1Q5N A;  2QVE A;  1FUP A;  1JSW A;  2E9F A;  1AUW A;  2FUS A;  2VL7 A;  2RJR A;  3R6Q A;  1U16 A;  3OCF A;  2OHY A;  2VSF A;  4FFX A;  2X75 A;  4V2Q A;  5EYT A;  2O78 A;  1FUR A;  1XMD A;  1TJ7 A;  4C5S A;  2PTQ A;  4WNL A;  4EFC A;  1FUQ A;  3CRW 1;  1T6J A;  1GKM A;  1XWO A;  2PTS A;  1RE5 A;  1XL8 A;  3NO9 A;  4ADL A;  3GTD A;  3E04 A;  5H8W A;  1J3U A;  1KQ7 A;  1K7W A;  4V2R A;  1HY0 A;  1DOF A;  1YIS A;  3CRV A;  2PTR A;  4A15 A;  2RJS A;  3KDZ A;  1XLY A;  3UNV A;  2PFM A;  3GZH A;  1GK3 A;  1EB4 A;  4APB A;  4CQ5 A;  1TJV A;  1YFM A;  1FUO A;  1GKJ A;  2YII A;  5D6B A;  2O7E A;  1U15 A;  4C5R A;  5HW2 A;  4ADM A;  1HY1 A;  2O6Y A;  4FLC A;  2O7D A;  3RRP A; 
#chains in the Genus database with same CATH homology
 5F92 A;  1B8F A;  2J91 A;  1Y2M A;  4C5U A;  1W27 A;  1C3U A;  3RD8 A;  1T6P A;  2HVG A;  3CZO A;  1VDK A;  1GK2 A;  3TV2 A;  2NYF A;  3NZ4 A;  1C3C A;  4NLE A;  2O7F A;  4APA A;  1TJU A;  3KDY A;  3R6Y A;  4NSL A;  3C8T A;  4MX2 A;  3OCE A;  4HGV A;  2QGA B;  1I0A A;  1TJW A;  3R6V A;  4BAB A;  2O7B A;  2NYN A;  2VD6 A;  5EYV A;  5F91 A;  4C6G A;  4BAA A;  1YFE A;  4EEI A;  3QBP A;  3BHG A;  1K62 A;  1DCN A;  1Q5N A;  2QVE A;  1FUP A;  1JSW A;  2E9F A;  1AUW A;  2FUS A;  2RJR A;  3R6Q A;  1U16 A;  3OCF A;  2OHY A;  4FFX A;  4V2Q A;  2X75 A;  5EYT A;  2O78 A;  1FUR A;  1TJ7 A;  4C5S A;  2PTQ A;  4EFC A;  1FUQ A;  1T6J A;  1GKM A;  1XWO A;  2PTS A;  1RE5 A;  3NO9 A;  4ADL A;  3GTD A;  3E04 A;  1J3U A;  1KQ7 A;  1K7W A;  4V2R A;  1HY0 A;  1DOF A;  1YIS A;  2PTR A;  2RJS A;  3KDZ A;  3UNV A;  2PFM A;  3GZH A;  1GK3 A;  1EB4 A;  4APB A;  4CQ5 A;  1TJV A;  1YFM A;  1FUO A;  1GKJ A;  2YII A;  5D6B A;  2O7E A;  1U15 A;  4C5R A;  5HW2 A;  4ADM A;  1HY1 A;  2O6Y A;  4FLC A;  2O7D A;  3RRP A; 
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