2RQBA

Solution structure of mda5 ctd
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
135
structure length
135
Chain Sequence
GPLGSYKNNPSLITFLCKNCSVLACSGEDIHVIEKMHHVNMTPEFKELYIVRENKALQKKCADYQINGEIICKCGQAWGTMMVHKGLDLPCLKIRNFVVVFKNNSTKKQYKKWVELPITFPNLDYSECCLFSDED
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution Structures of Cytosolic RNA Sensor MDA5 and LGP2 C-terminal Domains: IDENTIFICATION OF THE RNA RECOGNITION LOOP IN RIG-I-LIKE RECEPTORS
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Interferon-induced helicase C domain-containing protein 1
total genus 12
structure length 135
sequence length 135
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2009-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11648 RIG-I_C-RD C-terminal domain of RIG-I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 2rqbA00
3GA3A 5F98A 4A2XA 2QFBA 5F9HA 5E3HA 2QFDA 4BPBA 3ZD7A 2W4RA 3EQTA 4AY2A 4A2VA 3LRRA 2RQBA 2YKGA 3ZD6A 2RQAA 3NCUA 2RMJA 5F9FA 3LRNA 3OG8A
chains in the Genus database with same CATH superfamily
3GA3A 4V31A 5F98A 4A2XA 2HR9A 4CI2B 4TZCA 2QFBA 4V30A 5F9HA 1YZ1A 2QFDA 5E3HA 3FACA 4CI1B 4BPBA 3EBMA 2KV1A 2K8DA 3CXKA 3HCJA 3MAOA 1L1DA 1H7YA 2LVLA 3ZD7A 3P3KA 1HXRA 4CI3B 1FWQA 2W4RA 3E0MA 2KZNA 4TZ4C 4V2ZA 1TXJA 3HCGA 3WX1A 4A2VA 3EQTA 4AY2A 3E0OA 3LRRA 2RQBA 2YKGA 2KWBA 2FU5A 3WX2A 3ZD6A 1H6QA 2RQAA 4V2YA 3DJMA 2LOYA 5AMHA 3NCUA 2RMJA 4TZUA 5F9FA 3HCHA 3LRNA 3HCIA 3OG8A 3CEZA
chains in the Genus database with same CATH topology
3GA3A 5F98A 4A2XA 2HR9A 2QFBA 5F9HA 1YZ1A 2QFDA 5E3HA 3FACA 4BPBA 3EBMA 1H7YA 2LVLA 3ZD7A 3P3KA 1HXRA 1FWQA 2W4RA 1TXJA 3EQTA 4AY2A 4A2VA 3LRRA 2RQBA 2YKGA 2KWBA 2FU5A 3ZD6A 1H6QA 2RQAA 3DJMA 2LOYA 3NCUA 2RMJA 5F9FA 3LRNA 3OG8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GA3 A;  5F98 A;  4A2X A;  2QFB A;  5F9H A;  5E3H A;  2QFD A;  4BPB A;  3ZD7 A;  2W4R A;  3EQT A;  4AY2 A;  4A2V A;  3LRR A;  2RQB A;  2YKG A;  3ZD6 A;  2RQA A;  3NCU A;  2RMJ A;  5F9F A;  3LRN A;  3OG8 A; 
#chains in the Genus database with same CATH topology
 3GA3 A;  4V31 A;  5F98 A;  4A2X A;  2HR9 A;  4CI2 B;  4TZC A;  2QFB A;  4V30 A;  5F9H A;  1YZ1 A;  2QFD A;  5E3H A;  3FAC A;  4CI1 B;  4BPB A;  3EBM A;  2KV1 A;  2K8D A;  3CXK A;  3HCJ A;  3MAO A;  1L1D A;  1H7Y A;  2LVL A;  3ZD7 A;  3P3K A;  1HXR A;  4CI3 B;  1FWQ A;  2W4R A;  3E0M A;  2KZN A;  4TZ4 C;  4V2Z A;  1TXJ A;  3HCG A;  3WX1 A;  4A2V A;  3EQT A;  4AY2 A;  3E0O A;  3LRR A;  2RQB A;  2YKG A;  2KWB A;  2FU5 A;  3WX2 A;  3ZD6 A;  1H6Q A;  2RQA A;  4V2Y A;  3DJM A;  2LOY A;  5AMH A;  3NCU A;  2RMJ A;  4TZU A;  5F9F A;  3HCH A;  3LRN A;  3HCI A;  3OG8 A;  3CEZ A; 
#chains in the Genus database with same CATH homology
 3GA3 A;  5F98 A;  4A2X A;  2HR9 A;  2QFB A;  5F9H A;  1YZ1 A;  2QFD A;  5E3H A;  3FAC A;  4BPB A;  3EBM A;  1H7Y A;  2LVL A;  3ZD7 A;  3P3K A;  1HXR A;  1FWQ A;  2W4R A;  1TXJ A;  3EQT A;  4AY2 A;  4A2V A;  3LRR A;  2RQB A;  2YKG A;  2KWB A;  2FU5 A;  3ZD6 A;  1H6Q A;  2RQA A;  3DJM A;  2LOY A;  3NCU A;  2RMJ A;  5F9F A;  3LRN A;  3OG8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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