2SGEI

Glu 18 variant of turkey ovomucoid inhibitor third domain complexed with streptomyces griseus proteinase b at ph 10.7
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
51
structure length
51
Chain Sequence
VDCSEYPKPACTEEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Water molecules participate in proteinase-inhibitor interactions: crystal structures of Leu18, Ala18, and Gly18 variants of turkey ovomucoid inhibitor third domain complexed with Streptomyces griseus proteinase B.
pubmed doi rcsb
molecule keywords Streptogrisin B
molecule tags Hydrolase/hydrolase inhibitor
source organism Meleagris gallopavo
total genus 14
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 1999-03-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2sgeI00
1IW4A 2SGQI 1CGJI 2NU3I 2B0UC 1PJUA 2KMQA 3TJQA 2NU1I 1SGQI 5DAEA 1PPFI 1AN1I 1LR9A 1CHOI 2LEOA 1R0RI 1TBQR 2SGDI 1OMUA 1PCEA 1LR7A 2OVOA 2JXDA 2GKTI 2SGPI 1TUSA 1BMOA 2QQCA 1UVGA 2F3CI 3QTLD 1OMTA 1TGSI 1KMAA 1SGYI 2NU2I 1CT2I 5JHWC 1OYVI 1H0ZA 3HH2C 2JYYA 1CE3A 1M8CA 1OVOA 1TURA 2XRCA 1SGNI 1NUBA 1SGEI 1SGRI 2SGEI 1M8BA 2QQDA 1SGPI 1HDLA 1CT4I 2V53A 3SGBI 2N17A 3B4VC 1LR8A 2GKRI 1YU6C 2WCYA 1UUCA 1CSOI 4HGUA 1Y1BA 2N71A 2SGFI 2N52A 1SGDI 1DS2I 1UVFA 1BUSA 2JZMA 3SGQI 2KCXA 1CT0I 1TBRR 3SEKC 2NU0I 2GKVA 2ARPF 2KMRA 1FYBA 2KMOA 2BUSA 2P6AC 1Y1CA 1N13A 2ERWA 1Z7KB 4OVOA 3OVOA 1IY5A 1HPTA 2M5XA 1DS3I 4SGBI 1HJAI 2KMPA 1MT1A 1YTPA 1TIHA 2NU4I 4GI3C 1CGII 1IY6A
chains in the Genus database with same CATH superfamily
1IW4A 1WGCA 1Q9BA 2SGQI 3QAHA 3RU0A 1CGJI 3UGLA 3VE5A 2NU3I 2YQPA 2B0UC 1PJUA 3VDUA 2E5RA 2KMQA 3R5DA 1XX6A 5E3PA 3TJQA 1K7TA 2K9HA 5FUVA 1FAQA 4DNCA 2NU1I 3FC3A 5EX3A 2YUUA 2OD1A 1SGQI 1P9ZA 2UVOA 5DAEA 1PPFI 1FARA 1AN1I 3UEJA 5J8FA 1KBFA 1FY7A 1LR9A 1CHOI 2LEOA 1R0RI 2PQ8A 1MJ9A 1TBQR 2GVIA 3OXFA 4FKDA 2SGDI 3KY9A 4MPIA 2X3TA 1OMUA 1V1HA 2ELIA 1UHAA 1PCEA 2JA1A 2QQ0A 1LR7A 2OVOA 5HI7A 3FSXA 2JXDA 2B8TA 2GKTI 3D00A 2SGPI 3E2IA 5HQ8A 1K7UA 1Y8FA 1TUSA 2CWFA 2RC4A 5J8CA 2V1CC 7WGAA 1BMOA 4UXJA 1W4RA 5E3QA 1Z2IA 1UVGA 2F3CI 2QQCA 1ULNA 3QTLD 3R5BA 3UEYA 1OMTA 1TGSI 1U5KA 3UGIA 1TBNA 5CCMA 1SGYI 1MJBA 2A20A 1KMAA 3OXGA 2NU2I 1MJAA 1V1IA 1CT2I 2DIPA 1NXUA 2L8EA 3BJIA 5JHWC 1OYVI 2OU2A 1H0ZA 2FNFX 3QWPA 3HH2C 2JYYA 2N1AB 3TO6A 5FUXA 3CXLA 3MEKA 1M8CA 1CE3A 1ULKA 1OVOA 1TURA 2XRCA 3UGDA 2GIVA 1SGNI 1PTQA 3FSYA 3UOEA 1NUBA 4JCVE 1SGEI 1SGRI 2SGEI 1M8BA 4AMLA 4UXIA 1WTJA 5E3RA 1K7VA 2RIJA 2QQDA 2VRWB 1SGPI 1HDLA 1CT4I 2V53A 3SGBI 2N17A 2UZ3A 1LR8A 2GKRI 3B4VC 2ENZA 1YU6C 4B6DA 3VDPA 1XBTA 2OZUA 3PDNA 1ULMA 2CJSC 2WCYA 1RFHA 1UUCA 1WGTA 2ODDA 2E73A 1CSOI 2ROWA 3E59A 4HGUA 1KBEA 1Y1BA 2CWGA 5CCLA 2N71A 2SGFI 2N52A 1SGDI 1DS2I 1PTRA 3TO9A 1XA6A 1UVFA 3TOBA 1BUSA 2JZMA 2V1CA 4L9MA 3SGQI 2KCXA 2WGCA 1TOTA 1CT0I 1TBRR 2ORWA 2NU0I 3SEKC 2GKVA 1S20A 1W3SA 1X4SA 2ARPF 2J87A 2QQEA 3UFFA 3GOXA 2KMRA 1FYBA 2KMOA 2WVJA 3OL0A 2BUSA 3TO7A 2P6AC 4WP4A 1Y1CA 2W0TA 2CWHA 2LUYA 1N13A 2ERWA 1Z7KB 3R5CA 4OVOA 3OVOA 1WKXA 1IY5A 2X52A 2Y0MA 2J9RA 4E1RA 5FUYA 2QPOA 2L7XA 3R5AA 5EX0A 1HPTA 3TOAA 2DKVA 1VDDA 1DS3I 2M5XA 2ENNA 4SGBI 1HJAI 4UXHA 5FUWA 4E1PA 2KMPA 1MT1A 1YTPA 1TIHA 2NU4I 1R79A 2ORVA 2DB6A 1X74A 9WGAA 3OXLA 1HEVA 4GI3C 2LB7A 1CGII 2JW6A 4A24A 1P9GA 1TBOA 1IY6A
chains in the Genus database with same CATH topology
1IW4A 2SGQI 3RU0A 3VE5A 1CGJI 3UGLA 2NU3I 2YQPA 2B0UC 1PJUA 3VDUA 2E5RA 2KMQA 1XX6A 3TJQA 2K9HA 5FUVA 2NU1I 3FC3A 5EX3A 2YUUA 2OD1A 1SGQI 5DAEA 1PPFI 1FARA 1AN1I 3UEJA 1KBFA 1LR9A 1CHOI 2LEOA 1R0RI 4FKDA 1TBQR 2GVIA 3OXFA 2SGDI 3KY9A 1OMUA 1V1HA 2ELIA 2JA1A 1PCEA 2QQ0A 5HI7A 1LR7A 2OVOA 2JXDA 2B8TA 2GKTI 3D00A 2SGPI 3E2IA 5HQ8A 1Y8FA 1TUSA 2V1CC 1BMOA 4UXJA 1W4RA 2QQCA 1UVGA 2F3CI 3UEYA 3QTLD 3UGIA 1FAQA 1OMTA 1TGSI 1U5KA 5CCMA 1TBNA 1KMAA 1SGYI 2A20A 3OXGA 2NU2I 1V1IA 1CT2I 2DIPA 2L8EA 3BJIA 5JHWC 1OYVI 1H0ZA 2FNFX 3QWPA 3HH2C 2JYYA 2N1AB 1CE3A 5FUXA 3CXLA 3MEKA 1M8CA 1OVOA 1TURA 2XRCA 3UGDA 1SGNI 1PTQA 1NUBA 4JCVE 1SGEI 1SGRI 2SGEI 1M8BA 4UXIA 2QQDA 2VRWB 1SGPI 1HDLA 1CT4I 2V53A 3SGBI 2N17A 2UZ3A 1LR8A 2GKRI 3B4VC 2ENZA 1YU6C 4B6DA 3VDPA 1XBTA 3PDNA 2CJSC 2WCYA 1RFHA 1UUCA 2ODDA 2E73A 1CSOI 2ROWA 3E59A 4HGUA 1KBEA 1Y1BA 5CCLA 2N71A 2SGFI 2N52A 1SGDI 1DS2I 1PTRA 1XA6A 1UVFA 1BUSA 2JZMA 2V1CA 4L9MA 3SGQI 2KCXA 1TOTA 1CT0I 1TBRR 2ORWA 2NU0I 3SEKC 2GKVA 1X4SA 2ARPF 1W3SA 2J87A 3UFFA 2QQEA 3GOXA 2KMRA 1FYBA 2KMOA 2WVJA 3OL0A 2BUSA 2P6AC 1Y1CA 2W0TA 2LUYA 1N13A 2ERWA 1Z7KB 4OVOA 3OVOA 1IY5A 2J9RA 4E1RA 5FUYA 2QPOA 2L7XA 5EX0A 1HPTA 2M5XA 1VDDA 1DS3I 4UXHA 2ENNA 4SGBI 1HJAI 5FUWA 4E1PA 2KMPA 1MT1A 1YTPA 1TIHA 2NU4I 1R79A 2ORVA 2DB6A 1X74A 3OXLA 4GI3C 4A24A 1CGII 2JW6A 1TBOA 1IY6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IW4 A;  2SGQ I;  1CGJ I;  2NU3 I;  2B0U C;  1PJU A;  2KMQ A;  3TJQ A;  2NU1 I;  1SGQ I;  5DAE A;  1PPF I;  1AN1 I;  1LR9 A;  1CHO I;  2LEO A;  1R0R I;  1TBQ R;  2SGD I;  1OMU A;  1PCE A;  1LR7 A;  2OVO A;  2JXD A;  2GKT I;  2SGP I;  1TUS A;  1BMO A;  2QQC A;  1UVG A;  2F3C I;  3QTL D;  1OMT A;  1TGS I;  1KMA A;  1SGY I;  2NU2 I;  1CT2 I;  5JHW C;  1OYV I;  1H0Z A;  3HH2 C;  2JYY A;  1CE3 A;  1M8C A;  1OVO A;  1TUR A;  2XRC A;  1SGN I;  1NUB A;  1SGE I;  1SGR I;  2SGE I;  1M8B A;  2QQD A;  1SGP I;  1HDL A;  1CT4 I;  2V53 A;  3SGB I;  2N17 A;  3B4V C;  1LR8 A;  2GKR I;  1YU6 C;  2WCY A;  1UUC A;  1CSO I;  4HGU A;  1Y1B A;  2N71 A;  2SGF I;  2N52 A;  1SGD I;  1DS2 I;  1UVF A;  1BUS A;  2JZM A;  3SGQ I;  2KCX A;  1CT0 I;  1TBR R;  3SEK C;  2NU0 I;  2GKV A;  2ARP F;  2KMR A;  1FYB A;  2KMO A;  2BUS A;  2P6A C;  1Y1C A;  1N13 A;  2ERW A;  1Z7K B;  4OVO A;  3OVO A;  1IY5 A;  1HPT A;  2M5X A;  1DS3 I;  4SGB I;  1HJA I;  2KMP A;  1MT1 A;  1YTP A;  1TIH A;  2NU4 I;  4GI3 C;  1CGI I;  1IY6 A; 
#chains in the Genus database with same CATH topology
 1IW4 A;  1WGC A;  1Q9B A;  2SGQ I;  3QAH A;  3RU0 A;  1CGJ I;  3UGL A;  3VE5 A;  2NU3 I;  2YQP A;  2B0U C;  1PJU A;  3VDU A;  2E5R A;  2KMQ A;  3R5D A;  1XX6 A;  5E3P A;  3TJQ A;  1K7T A;  2K9H A;  5FUV A;  1FAQ A;  4DNC A;  2NU1 I;  3FC3 A;  5EX3 A;  2YUU A;  2OD1 A;  1SGQ I;  1P9Z A;  2UVO A;  5DAE A;  1PPF I;  1FAR A;  1AN1 I;  3UEJ A;  5J8F A;  1KBF A;  1FY7 A;  1LR9 A;  1CHO I;  2LEO A;  1R0R I;  2PQ8 A;  1MJ9 A;  1TBQ R;  2GVI A;  3OXF A;  4FKD A;  2SGD I;  3KY9 A;  4MPI A;  2X3T A;  1OMU A;  1V1H A;  2ELI A;  1UHA A;  1PCE A;  2JA1 A;  2QQ0 A;  1LR7 A;  2OVO A;  5HI7 A;  3FSX A;  2JXD A;  2B8T A;  2GKT I;  3D00 A;  2SGP I;  3E2I A;  5HQ8 A;  1K7U A;  1Y8F A;  1TUS A;  2CWF A;  2RC4 A;  5J8C A;  2V1C C;  7WGA A;  1BMO A;  4UXJ A;  1W4R A;  5E3Q A;  1Z2I A;  1UVG A;  2F3C I;  2QQC A;  1ULN A;  3QTL D;  3R5B A;  3UEY A;  1OMT A;  1TGS I;  1U5K A;  3UGI A;  1TBN A;  5CCM A;  1SGY I;  1MJB A;  2A20 A;  1KMA A;  3OXG A;  2NU2 I;  1MJA A;  1V1I A;  1CT2 I;  2DIP A;  1NXU A;  2L8E A;  3BJI A;  5JHW C;  1OYV I;  2OU2 A;  1H0Z A;  2FNF X;  3QWP A;  3HH2 C;  2JYY A;  2N1A B;  3TO6 A;  5FUX A;  3CXL A;  3MEK A;  1M8C A;  1CE3 A;  1ULK A;  1OVO A;  1TUR A;  2XRC A;  3UGD A;  2GIV A;  1SGN I;  1PTQ A;  3FSY A;  3UOE A;  1NUB A;  4JCV E;  1SGE I;  1SGR I;  2SGE I;  1M8B A;  4AML A;  4UXI A;  1WTJ A;  5E3R A;  1K7V A;  2RIJ A;  2QQD A;  2VRW B;  1SGP I;  1HDL A;  1CT4 I;  2V53 A;  3SGB I;  2N17 A;  2UZ3 A;  1LR8 A;  2GKR I;  3B4V C;  2ENZ A;  1YU6 C;  4B6D A;  3VDP A;  1XBT A;  2OZU A;  3PDN A;  1ULM A;  2CJS C;  2WCY A;  1RFH A;  1UUC A;  1WGT A;  2ODD A;  2E73 A;  1CSO I;  2ROW A;  3E59 A;  4HGU A;  1KBE A;  1Y1B A;  2CWG A;  5CCL A;  2N71 A;  2SGF I;  2N52 A;  1SGD I;  1DS2 I;  1PTR A;  3TO9 A;  1XA6 A;  1UVF A;  3TOB A;  1BUS A;  2JZM A;  2V1C A;  4L9M A;  3SGQ I;  2KCX A;  2WGC A;  1TOT A;  1CT0 I;  1TBR R;  2ORW A;  2NU0 I;  3SEK C;  2GKV A;  1S20 A;  1W3S A;  1X4S A;  2ARP F;  2J87 A;  2QQE A;  3UFF A;  3GOX A;  2KMR A;  1FYB A;  2KMO A;  2WVJ A;  3OL0 A;  2BUS A;  3TO7 A;  2P6A C;  4WP4 A;  1Y1C A;  2W0T A;  2CWH A;  2LUY A;  1N13 A;  2ERW A;  1Z7K B;  3R5C A;  4OVO A;  3OVO A;  1WKX A;  1IY5 A;  2X52 A;  2Y0M A;  2J9R A;  4E1R A;  5FUY A;  2QPO A;  2L7X A;  3R5A A;  5EX0 A;  1HPT A;  3TOA A;  2DKV A;  1VDD A;  1DS3 I;  2M5X A;  2ENN A;  4SGB I;  1HJA I;  4UXH A;  5FUW A;  4E1P A;  2KMP A;  1MT1 A;  1YTP A;  1TIH A;  2NU4 I;  1R79 A;  2ORV A;  2DB6 A;  1X74 A;  9WGA A;  3OXL A;  1HEV A;  4GI3 C;  2LB7 A;  1CGI I;  2JW6 A;  4A24 A;  1P9G A;  1TBO A;  1IY6 A; 
#chains in the Genus database with same CATH homology
 1IW4 A;  2SGQ I;  3RU0 A;  3VE5 A;  1CGJ I;  3UGL A;  2NU3 I;  2YQP A;  2B0U C;  1PJU A;  3VDU A;  2E5R A;  2KMQ A;  1XX6 A;  3TJQ A;  2K9H A;  5FUV A;  2NU1 I;  3FC3 A;  5EX3 A;  2YUU A;  2OD1 A;  1SGQ I;  5DAE A;  1PPF I;  1FAR A;  1AN1 I;  3UEJ A;  1KBF A;  1LR9 A;  1CHO I;  2LEO A;  1R0R I;  4FKD A;  1TBQ R;  2GVI A;  3OXF A;  2SGD I;  3KY9 A;  1OMU A;  1V1H A;  2ELI A;  2JA1 A;  1PCE A;  2QQ0 A;  5HI7 A;  1LR7 A;  2OVO A;  2JXD A;  2B8T A;  2GKT I;  3D00 A;  2SGP I;  3E2I A;  5HQ8 A;  1Y8F A;  1TUS A;  2V1C C;  1BMO A;  4UXJ A;  1W4R A;  2QQC A;  1UVG A;  2F3C I;  3UEY A;  3QTL D;  3UGI A;  1FAQ A;  1OMT A;  1TGS I;  1U5K A;  5CCM A;  1TBN A;  1KMA A;  1SGY I;  2A20 A;  3OXG A;  2NU2 I;  1V1I A;  1CT2 I;  2DIP A;  2L8E A;  3BJI A;  5JHW C;  1OYV I;  1H0Z A;  2FNF X;  3QWP A;  3HH2 C;  2JYY A;  2N1A B;  1CE3 A;  5FUX A;  3CXL A;  3MEK A;  1M8C A;  1OVO A;  1TUR A;  2XRC A;  3UGD A;  1SGN I;  1PTQ A;  1NUB A;  4JCV E;  1SGE I;  1SGR I;  2SGE I;  1M8B A;  4UXI A;  2QQD A;  2VRW B;  1SGP I;  1HDL A;  1CT4 I;  2V53 A;  3SGB I;  2N17 A;  2UZ3 A;  1LR8 A;  2GKR I;  3B4V C;  2ENZ A;  1YU6 C;  4B6D A;  3VDP A;  1XBT A;  3PDN A;  2CJS C;  2WCY A;  1RFH A;  1UUC A;  2ODD A;  2E73 A;  1CSO I;  2ROW A;  3E59 A;  4HGU A;  1KBE A;  1Y1B A;  5CCL A;  2N71 A;  2SGF I;  2N52 A;  1SGD I;  1DS2 I;  1PTR A;  1XA6 A;  1UVF A;  1BUS A;  2JZM A;  2V1C A;  4L9M A;  3SGQ I;  2KCX A;  1TOT A;  1CT0 I;  1TBR R;  2ORW A;  2NU0 I;  3SEK C;  2GKV A;  1X4S A;  2ARP F;  1W3S A;  2J87 A;  3UFF A;  2QQE A;  3GOX A;  2KMR A;  1FYB A;  2KMO A;  2WVJ A;  3OL0 A;  2BUS A;  2P6A C;  1Y1C A;  2W0T A;  2LUY A;  1N13 A;  2ERW A;  1Z7K B;  4OVO A;  3OVO A;  1IY5 A;  2J9R A;  4E1R A;  5FUY A;  2QPO A;  2L7X A;  5EX0 A;  1HPT A;  2M5X A;  1VDD A;  1DS3 I;  4UXH A;  2ENN A;  4SGB I;  1HJA I;  5FUW A;  4E1P A;  2KMP A;  1MT1 A;  1YTP A;  1TIH A;  2NU4 I;  1R79 A;  2ORV A;  2DB6 A;  1X74 A;  3OXL A;  4GI3 C;  4A24 A;  1CGI I;  2JW6 A;  1TBO A;  1IY6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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