2UUUA

Alkyldihydroxyacetonephosphate synthase in p212121
Total Genus 181
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
181
sequence length
581
structure length
550
Chain Sequence
MGSPKEHIDLYQQIKWNGWGDTRKFLHQLKPSGTIAMTTPEVSSVPLPSLRGFIKKELTKPFVLDETPALQIENIHVDPPKQYPEFVRELKAFFLPDQLKDDKLARITHTFGKSLRDLIRVRIGQVKNAPDLIVLPHSHEEVERLVQLAHKYNVVIIPMGGGSNIVGAIEPVSNERFTVSIDMRRMNKVLWVDRREMTACIQVGIMGPELEKQLHKQGVSLGHDPDSFEFSTLGGWLATCSSGHQSDKYGDIEDMAVSFRTVTPTGTLELRGINYKHIILGSEGTLGIITEAVMKVHAVPQAVEYYGFLFPTFAHAVSALQQIRSSEVIPTMIRVYDPEETQLSFAWKPSKGAVSEFTSAMVKKYLHYIRSFDFKNVCLSIIGFEGPKKVVDFHRTSVFDILSKNAAFGLGSAPGKTWAEKRYDLPYIRDFLLDHNMWVDVAETTVSYANLQTLWKDAKQTFVKHFKDQGIPAWICAHISHTYTNGVCLYFIFASKQNENKDMAQYIEAKKLMTDIIFKYGGSLSRGWINVYRSLKETIDPKDICNPRKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Crucial Step in Ether Phospholipid Biosynthesis: Structural Basis of a Noncanonical Reaction Associated with a Peroxisomal Disorder.
pubmed doi rcsb
molecule tags Transferase
source organism Dictyostelium discoideum
molecule keywords ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE
total genus 181
structure length 550
sequence length 581
chains with identical sequence B, C, D
ec nomenclature ec 2.5.1.26: Alkylglycerone-phosphate synthase.
pdb deposition date 2007-03-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.465.40 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 2uuuA02
3.40.462.40 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 2uuuA01
2Y08A 5L6FA 2Y3RA 5L6GA 2UUUA 2Y3SA 3PQBA 5I1WA 3HSUA 5AWVA 2Y4GA 2IPIA 3RJ8A 2WDWA 5I1VA 5K8EA 3RJAA 3POPA 2UUVA
chains in the Genus database with same CATH superfamily
2PLIA 3C0PA 3W8XA 1DIQA 1JRPA 2R8DA 2EXRA 3D2JA 4PWCA 2P3HA 2O3GA 5G5HB 5L6GA 5AE2A 1W1SA 2UUUA 2AXRA 3GSYA 1AHZA 1W1LA 3D2HA 2Q85A 4HG0A 1N61C 2VFTA 3NVWB 3B9JB 3EUB3 1VDVA 2Y4GA 1N60C 1VAOA 4PYTA 2WDWA 3I99A 4PWBA 1E8GA 1ZR6A 4UD8A 2GQUA 3D2DA 2BVGA 2YVSA 4OALA 1FFVC 3BW7A 3AMZA 3NS1B 1JROA 1AHUA 2OAIA 1FFUC 2VAOA 1FO4A 5HMRA 1W1MA 3FW9A 4ML8A 3DQ0A 1WVEA 3W8ZA 1N5WC 1T3QC 2P13A 3SR6B 2Y3SA 3DEDA 4O95A 1HSKA 3AM9A 5D79A 1E0YA 2VFVA 1MBTA 3AN1A 4DNSA 1E8HA 3LLBA 5AWVA 2I0KA 3TX1A 1SB3B 1W1JA 4PVEA 1DIIA 3RJ8A 3TSJA 2MBRA 2GQTA 2W3RA 1E8FA 2BVHA 5FXFA 3PM9A 4BBYA 1N62C 2P4PA 2R2ZA 3POPA 3NVZB 4BC9A 2E3TA 3KJMA 2VFUA 2NQWA 2Y08A 3FW8A 3TSHA 5FXPA 3ETRB 5FXDA 4BC7A 3PQBA 1W1OA 5G5GB 4XLOA 1W1RA 5I1WA 3HSUA 3LAEA 2IPIA 3VTEA 2VFSA 1QLUA 2VFRA 1RM6B 2QKNA 4ZOHB 3S1DA 4PVJA 3S1FA 1WVFA 2PLSA 5HQXA 4MLAA 3JS8A 2BVFA 2W55A 5AE1A 4PVHA 1DZNA 4PVKA 2UUVA 3NVVB 1I19A 1MBBA 1UXYA 5L6FA 2Y3RA 1F0XA 3S1CA 5ADZA 2W54A 3S1EA 1FIQB 1N5XA 1V97A 1AHVA 4EC3A 1QLTA 3FWAA 3NVYB 5FXEA 3W8WA 5K8EA 5I1VA 1WYGA 1W1KA 5HHZA 4JAYA 3HRDC 3FW7A 1ZXIC 4BCAA 2RK5A 5AE3A 2W3SA 2Q4WA 2QPMA 3RJAA 4JB1A 3NRZB 1W1QA 4PZFA 1N63C
chains in the Genus database with same CATH topology
2PLIA 3C0PA 3W8XA 1DIQA 1JRPA 2R8DA 2EXRA 3D2JA 4PWCA 2P3HA 2O3GA 5G5HB 5L6GA 5AE2A 1W1SA 2UUUA 2AXRA 3GSYA 1AHZA 1W1LA 3D2HA 2Q85A 4HG0A 1N61C 2VFTA 3NVWB 3B9JB 3EUB3 1VDVA 2Y4GA 1N60C 1VAOA 4PYTA 2WDWA 3I99A 4PWBA 1E8GA 1ZR6A 4UD8A 2GQUA 3D2DA 2BVGA 2YVSA 4OALA 1FFVC 3BW7A 3AMZA 3NS1B 1JROA 1AHUA 2OAIA 1FFUC 2VAOA 1FO4A 5HMRA 1W1MA 3FW9A 4ML8A 3DQ0A 1WVEA 3W8ZA 1N5WC 1T3QC 2P13A 3SR6B 2Y3SA 3DEDA 4O95A 1HSKA 3AM9A 5D79A 1E0YA 2VFVA 1MBTA 3AN1A 4DNSA 1E8HA 3LLBA 5AWVA 2I0KA 3TX1A 1SB3B 1W1JA 4PVEA 1DIIA 3RJ8A 3TSJA 2MBRA 2GQTA 2W3RA 1E8FA 2BVHA 5FXFA 3PM9A 4BBYA 1N62C 2P4PA 2R2ZA 3POPA 3NVZB 4BC9A 2E3TA 3KJMA 2VFUA 2NQWA 2Y08A 3FW8A 3TSHA 5FXPA 3ETRB 5FXDA 4BC7A 3PQBA 1W1OA 5G5GB 4XLOA 1W1RA 5I1WA 3HSUA 3LAEA 2IPIA 3VTEA 2VFSA 1QLUA 2VFRA 1RM6B 2QKNA 4ZOHB 3S1DA 4PVJA 3S1FA 1WVFA 2PLSA 5HQXA 4MLAA 3JS8A 2BVFA 2W55A 5AE1A 4PVHA 1DZNA 4PVKA 2UUVA 3NVVB 1I19A 1MBBA 1UXYA 5L6FA 2Y3RA 1F0XA 3S1CA 5ADZA 2W54A 3S1EA 1FIQB 1N5XA 1V97A 1AHVA 4EC3A 1QLTA 3FWAA 3NVYB 5FXEA 3W8WA 5K8EA 5I1VA 1WYGA 1W1KA 5HHZA 4JAYA 3HRDC 3FW7A 1ZXIC 4BCAA 2RK5A 5AE3A 2W3SA 2Q4WA 2QPMA 3RJAA 4JB1A 3NRZB 1W1QA 4PZFA 1N63C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y08 A;  5L6F A;  2Y3R A;  5L6G A;  2UUU A;  2Y3S A;  3PQB A;  5I1W A;  3HSU A;  5AWV A;  2Y4G A;  2IPI A;  3RJ8 A;  2WDW A;  5I1V A;  5K8E A;  3RJA A;  3POP A;  2UUV A; 
#chains in the Genus database with same CATH topology
 2PLI A;  3C0P A;  3W8X A;  1DIQ A;  1JRP A;  2R8D A;  2EXR A;  3D2J A;  4PWC A;  2P3H A;  2O3G A;  5G5H B;  5L6G A;  5AE2 A;  1W1S A;  2UUU A;  2AXR A;  3GSY A;  1AHZ A;  1W1L A;  3D2H A;  2Q85 A;  4HG0 A;  1N61 C;  2VFT A;  3NVW B;  3B9J B;  3EUB 3;  1VDV A;  2Y4G A;  1N60 C;  1VAO A;  4PYT A;  2WDW A;  3I99 A;  4PWB A;  1E8G A;  1ZR6 A;  4UD8 A;  2GQU A;  3D2D A;  2BVG A;  2YVS A;  4OAL A;  1FFV C;  3BW7 A;  3AMZ A;  3NS1 B;  1JRO A;  1AHU A;  2OAI A;  1FFU C;  2VAO A;  1FO4 A;  5HMR A;  1W1M A;  3FW9 A;  4ML8 A;  3DQ0 A;  1WVE A;  3W8Z A;  1N5W C;  1T3Q C;  2P13 A;  3SR6 B;  2Y3S A;  3DED A;  4O95 A;  1HSK A;  3AM9 A;  5D79 A;  1E0Y A;  2VFV A;  1MBT A;  3AN1 A;  4DNS A;  1E8H A;  3LLB A;  5AWV A;  2I0K A;  3TX1 A;  1SB3 B;  1W1J A;  4PVE A;  1DII A;  3RJ8 A;  3TSJ A;  2MBR A;  2GQT A;  2W3R A;  1E8F A;  2BVH A;  5FXF A;  3PM9 A;  4BBY A;  1N62 C;  2P4P A;  2R2Z A;  3POP A;  3NVZ B;  4BC9 A;  2E3T A;  3KJM A;  2VFU A;  2NQW A;  2Y08 A;  3FW8 A;  3TSH A;  5FXP A;  3ETR B;  5FXD A;  4BC7 A;  3PQB A;  1W1O A;  5G5G B;  4XLO A;  1W1R A;  5I1W A;  3HSU A;  3LAE A;  2IPI A;  3VTE A;  2VFS A;  1QLU A;  2VFR A;  1RM6 B;  2QKN A;  4ZOH B;  3S1D A;  4PVJ A;  3S1F A;  1WVF A;  2PLS A;  5HQX A;  4MLA A;  3JS8 A;  2BVF A;  2W55 A;  5AE1 A;  4PVH A;  1DZN A;  4PVK A;  2UUV A;  3NVV B;  1I19 A;  1MBB A;  1UXY A;  5L6F A;  2Y3R A;  1F0X A;  3S1C A;  5ADZ A;  2W54 A;  3S1E A;  1FIQ B;  1N5X A;  1V97 A;  1AHV A;  4EC3 A;  1QLT A;  3FWA A;  3NVY B;  5FXE A;  3W8W A;  5K8E A;  5I1V A;  1WYG A;  1W1K A;  5HHZ A;  4JAY A;  3HRD C;  3FW7 A;  1ZXI C;  4BCA A;  2RK5 A;  5AE3 A;  2W3S A;  2Q4W A;  2QPM A;  3RJA A;  4JB1 A;  3NRZ B;  1W1Q A;  4PZF A;  1N63 C; 
#chains in the Genus database with same CATH homology
 2PLI A;  3C0P A;  3W8X A;  1DIQ A;  1JRP A;  2R8D A;  2EXR A;  3D2J A;  4PWC A;  2P3H A;  2O3G A;  5G5H B;  5L6G A;  5AE2 A;  1W1S A;  2UUU A;  2AXR A;  3GSY A;  1AHZ A;  1W1L A;  3D2H A;  2Q85 A;  4HG0 A;  1N61 C;  2VFT A;  3NVW B;  3B9J B;  3EUB 3;  1VDV A;  2Y4G A;  1N60 C;  1VAO A;  4PYT A;  2WDW A;  3I99 A;  4PWB A;  1E8G A;  1ZR6 A;  4UD8 A;  2GQU A;  3D2D A;  2BVG A;  2YVS A;  4OAL A;  1FFV C;  3BW7 A;  3AMZ A;  3NS1 B;  1JRO A;  1AHU A;  2OAI A;  1FFU C;  2VAO A;  1FO4 A;  5HMR A;  1W1M A;  3FW9 A;  4ML8 A;  3DQ0 A;  1WVE A;  3W8Z A;  1N5W C;  1T3Q C;  2P13 A;  3SR6 B;  2Y3S A;  3DED A;  4O95 A;  1HSK A;  3AM9 A;  5D79 A;  1E0Y A;  2VFV A;  1MBT A;  3AN1 A;  4DNS A;  1E8H A;  3LLB A;  5AWV A;  2I0K A;  3TX1 A;  1SB3 B;  1W1J A;  4PVE A;  1DII A;  3RJ8 A;  3TSJ A;  2MBR A;  2GQT A;  2W3R A;  1E8F A;  2BVH A;  5FXF A;  3PM9 A;  4BBY A;  1N62 C;  2P4P A;  2R2Z A;  3POP A;  3NVZ B;  4BC9 A;  2E3T A;  3KJM A;  2VFU A;  2NQW A;  2Y08 A;  3FW8 A;  3TSH A;  5FXP A;  3ETR B;  5FXD A;  4BC7 A;  3PQB A;  1W1O A;  5G5G B;  4XLO A;  1W1R A;  5I1W A;  3HSU A;  3LAE A;  2IPI A;  3VTE A;  2VFS A;  1QLU A;  2VFR A;  1RM6 B;  2QKN A;  4ZOH B;  3S1D A;  4PVJ A;  3S1F A;  1WVF A;  2PLS A;  5HQX A;  4MLA A;  3JS8 A;  2BVF A;  2W55 A;  5AE1 A;  4PVH A;  1DZN A;  4PVK A;  2UUV A;  3NVV B;  1I19 A;  1MBB A;  1UXY A;  5L6F A;  2Y3R A;  1F0X A;  3S1C A;  5ADZ A;  2W54 A;  3S1E A;  1FIQ B;  1N5X A;  1V97 A;  1AHV A;  4EC3 A;  1QLT A;  3FWA A;  3NVY B;  5FXE A;  3W8W A;  5K8E A;  5I1V A;  1WYG A;  1W1K A;  5HHZ A;  4JAY A;  3HRD C;  3FW7 A;  1ZXI C;  4BCA A;  2RK5 A;  5AE3 A;  2W3S A;  2Q4W A;  2QPM A;  3RJA A;  4JB1 A;  3NRZ B;  1W1Q A;  4PZF A;  1N63 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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