2UXWA

Crystal structure of human very long chain acyl-coa dehydrogenase (acadvl)
Total Genus 213
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
213
sequence length
587
structure length
567
Chain Sequence
b'QSMSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFGSGLSLSGLVHPELSRSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords VERY-LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE
publication title Crystal Structure of Human Very Long Chain Acyl- Coa Dehydrogenase (Acadvl)
rcsb
source organism Homo sapiens
molecule tags Oxidoreductase
total genus 213
structure length 567
sequence length 587
ec nomenclature ec 1.3.8.9: Very-long-chain acyl-CoA dehydrogenase.
pdb deposition date 2007-03-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 2uxwA02
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 2uxwA04
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 2uxwA01
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 2uxwA03
3R7KA 1FS7A 3MXLA 4Q5BA 3LGQA 3UBRA 3SWOA 2IX6A 2YYMA 3F29A 1EGEA 4G5EA 2YYIA 4Q1OA 1SIRA 4HR3A 3GQTA 1T9GA 4ZYJA 4KCFA 3HWCA 3SXQA 1IS2A 3TTBA 2R0MA 4NXLA 1OAHA 3D9FA 3B96A 5K3GA 4Q5CA 1JQIA 2DVLA 1EGDA 3GNCA 2DDHA 3MDDA 2D29A 3D9GA 4IRNA 4WJYA 1SIQA 1BUCA 2OR0A 2ZAFA 3BNGA 3OIBA 3OWMA 4OO2A 3D9EA 2IX5A 3MPJA 2C12A 1GU6A 2YYLA 3EOMA 3TORA 3SF6A 4N5FA 2JBRA 3MDEA 2RF7A 4DOYA 3FCJA 2CX9A 1QDBA 5K3JA 2J7AA 3BNHA 4X28C 2RDZA 4IV6A 4L1FA 3P4TA 4XVXA 5K3HA 2R0NA 1FS9A 2OT4A 2EBAA 3M9VA 4ZXVA 2YYJA 2ZO5A 2PG0A 3OWAA 4Q17A 3RKHA 2A1TA 1RX0A 3X0YA 2YYKA 3MKHA 1R2JA 4W9UA 1FS8A 3D6BA 4RM7A 3BNFA 3BNJA 2JIFA 3MPIA 3NF4A 4L3YA 4O5MA 3D1IA 3X0XA 4KTOA 3FO3A 3EONA 3D9DA 4P13A 1EGCA 3S7WA 3UU9A 2REHA 3GM6A 3AFEA 4M9AA 2E81A 4L3XA 2UXWA 4X28A 2VIGA 4Q0TA 2FONA 5K3IA 2RFQA 2Z1QA 1U8VA 2E80A 3SCEA 3LG1A 4L38A 2C0UA 1W07A 2JBTA 2WBIA 1WS9A 2JBSA 4JEKA 1IVHA 4L3ZA 3AFFA 2VR0A 4Q4UA 1UDYA 3II9A 4U83A 3PFDA 3L1TA 2YYGA 3MMOA 1UKWA
chains in the Genus database with same CATH superfamily
3R7KA 2ZKJA 2FP2A 1FS7A 4FF1A 3MXLA 4H85A 5M4NA 4MP7A 4Q5BA 3LGQA 2E0AA 2OEVA 3UBRA 3SWOA 2IX6A 2YYMA 3F29A 2OJQA 2XS1A 1EGEA 3TZ5A 3C2PA 4G5EA 1XFZA 2YYIA 4Q1OA 3TZ2A 1SIRA 5EZ3A 4HR3A 3GQTA 2YGWA 1T9GA 4ZYJA 4KCFA 3HWCA 4HKSA 3SXQA 3DJLA 1IS2A 3TTBA 1X90A 3TZ4A 1SK6A 2R0MA 4NXLA 5BRMA 1OAHA 1Y8OA 3D9FA 3CRKA 3B96A 2BU7A 2CJ5A 4DZYA 5K3GA 4LQSB 2ZDYA 2BU2A 2OEXA 4Q5CA 1JQIA 2DVLA 2EC5A 1EGDA 3GNCA 4MP2A 2FP1A 2DDHA 3VADA 3MDDA 2D29A 3D9GA 4IRNA 4WJYA 3X29A 2BU5A 1SIQA 3C3LA 1BUCA 2R02A 2OR0A 2ZAFA 2PO4A 3OIBA 3BNGA 3OWMA 4OO2A 3VKHA 3D9EA 3U33A 2ZDXA 2IX5A 3MPJA 2C12A 1GU6A 2YYLA 2Q8HA 3EOMA 2Q8FA 3TORA 5J6AA 3SF6A 3MMOA 4N5FA 2JBRA 3MDEA 1Y0VA 2RF7A 4DOYA 1K93A 1Y8NA 2PNRA 2CJ8A 3D2RA 3C46A 3FCJA 2CX9A 1GKZA 1QDBA 5K3JA 2J7AA 2AZEA 5J71A 2EBHX 2EBFX 3BNHA 4P79A 4X28C 2CJ7A 5GJWE 5B5VA 5B5WA 4F0XA 2RDZA 4IV6A 2VF1A 1JM6A 4L1FA 3P4TA 4XVXA 1S26A 4E01A 3N0RA 5K3HA 4KS9A 4FF4A 1PK0A 5M4KA 5BRKA 2HJNA 2R0NA 1X91A 1XFUA 4AKGA 1FS9A 2LFWA 2BU8A 2CJ4A 2OT4A 2EBAA 3M9VA 5M4MA 4ZXVA 2YYJA 1Y8PA 1XFWA 2XS8A 2PG0A 3OWAA 1RJ4A 2ZO5A 4JIOA 4Q17A 3Q24A 3VKGA 1X8ZA 3RKHA 2Q8GA 2A1TA 1RX0A 1PI1A 4KSAA 4FF3A 4KSFA 3X0YA 2YYKA 3TZ0A 4HKRA 3MKHA 1R2JA 2BU6A 2F6LA 4W9UA 1FS8A 3D6BA 4RM7A 1RJ1A 3BNFA 3BNJA 2JIFA 3MPIA 5GJVE 3NF4A 4QICA 1GJVA 4L3YA 1XFVA 4O5MA 3D1IA 2AO2A 3CRLA 3X0XA 4LQQB 4KTOA 1XG2B 2GBBA 4V25A 3FO3A 3EONA 4AKHA 3D9DA 4P13A 4AKIA 1EGCA 4FZ4A 3S7WA 3UU9A 2REHA 1LVCA 2BTZA 4MPCA 3Q22A 5B6BA 3GM6A 3Q23A 3AFEA 1R3BA 3KMLA 4V26A 4M9AA 2E81A 4H7QA 4L3XA 2UXWA 4X28A 2VIGA 4Q0TA 4FF2A 2FONA 5K3IA 1K90A 2RFQA 2Z1QA 1U8VA 2E80A 3SCEA 3LG1A 2R03A 4L38A 3Q0AA 1XFXA 4G97A 2C0UA 1W07A 2JBTA 2WBIA 1XFYA 1K8TA 1WS9A 2CJ6A 3CE2A 1GKXA 4E00A 4AI6A 2JBSA 4MPEA 4MPNA 4JEKA 5M4PA 1IVHA 2Q8IA 4JIZA 4L3ZA 1SC5A 4J1VA 3AFFA 2R05A 2VR0A 4Q4UA 1UDYA 2QR4A 3II9A 4U83A 3PFDA 1RP3A 3L1TA 4H81A 4E02A 2YYGA 2XQRB 1UKWA
chains in the Genus database with same CATH topology
3R7KA 1FS7A 3MXLA 4Q5BA 3LGQA 3UBRA 3SWOA 2IX6A 2YYMA 3F29A 1EGEA 4G5EA 2YYIA 4Q1OA 1SIRA 4HR3A 3GQTA 1T9GA 4ZYJA 4KCFA 3HWCA 3SXQA 1IS2A 3TTBA 2R0MA 4NXLA 1OAHA 3D9FA 3B96A 5K3GA 4Q5CA 1JQIA 2DVLA 1EGDA 3GNCA 2DDHA 3MDDA 2D29A 3D9GA 4IRNA 4WJYA 1SIQA 1BUCA 2OR0A 2ZAFA 3BNGA 3OIBA 3OWMA 4OO2A 3D9EA 2IX5A 3MPJA 2C12A 1GU6A 2YYLA 3EOMA 3TORA 3SF6A 4N5FA 2JBRA 3MDEA 2RF7A 4DOYA 3FCJA 2CX9A 1QDBA 5K3JA 2J7AA 3BNHA 4X28C 2RDZA 4IV6A 4L1FA 3P4TA 4XVXA 5K3HA 2R0NA 1FS9A 2OT4A 2EBAA 3M9VA 4ZXVA 2YYJA 2ZO5A 2PG0A 3OWAA 4Q17A 3RKHA 2A1TA 1RX0A 3X0YA 2YYKA 3MKHA 1R2JA 4W9UA 1FS8A 3D6BA 4RM7A 3BNFA 3BNJA 2JIFA 3MPIA 3NF4A 4L3YA 4O5MA 3D1IA 3X0XA 4KTOA 3FO3A 3EONA 3D9DA 4P13A 1EGCA 3S7WA 3UU9A 2REHA 3GM6A 3AFEA 4M9AA 2E81A 4L3XA 2UXWA 4X28A 2VIGA 4Q0TA 2FONA 5K3IA 2RFQA 2Z1QA 1U8VA 2E80A 3SCEA 3LG1A 4L38A 2C0UA 1W07A 2JBTA 2WBIA 1WS9A 2JBSA 4JEKA 1IVHA 4L3ZA 3AFFA 2VR0A 4Q4UA 1UDYA 3II9A 4U83A 3PFDA 3L1TA 2YYGA 3MMOA 1UKWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3R7K A;  1FS7 A;  3MXL A;  4Q5B A;  3LGQ A;  3UBR A;  3SWO A;  2IX6 A;  2YYM A;  3F29 A;  1EGE A;  4G5E A;  2YYI A;  4Q1O A;  1SIR A;  4HR3 A;  3GQT A;  1T9G A;  4ZYJ A;  4KCF A;  3HWC A;  3SXQ A;  1IS2 A;  3TTB A;  2R0M A;  4NXL A;  1OAH A;  3D9F A;  3B96 A;  5K3G A;  4Q5C A;  1JQI A;  2DVL A;  1EGD A;  3GNC A;  2DDH A;  3MDD A;  2D29 A;  3D9G A;  4IRN A;  4WJY A;  1SIQ A;  1BUC A;  2OR0 A;  2ZAF A;  3BNG A;  3OIB A;  3OWM A;  4OO2 A;  3D9E A;  2IX5 A;  3MPJ A;  2C12 A;  1GU6 A;  2YYL A;  3EOM A;  3TOR A;  3SF6 A;  4N5F A;  2JBR A;  3MDE A;  2RF7 A;  4DOY A;  3FCJ A;  2CX9 A;  1QDB A;  5K3J A;  2J7A A;  3BNH A;  4X28 C;  2RDZ A;  4IV6 A;  4L1F A;  3P4T A;  4XVX A;  5K3H A;  2R0N A;  1FS9 A;  2OT4 A;  2EBA A;  3M9V A;  4ZXV A;  2YYJ A;  2ZO5 A;  2PG0 A;  3OWA A;  4Q17 A;  3RKH A;  2A1T A;  1RX0 A;  3X0Y A;  2YYK A;  3MKH A;  1R2J A;  4W9U A;  1FS8 A;  3D6B A;  4RM7 A;  3BNF A;  3BNJ A;  2JIF A;  3MPI A;  3NF4 A;  4L3Y A;  4O5M A;  3D1I A;  3X0X A;  4KTO A;  3FO3 A;  3EON A;  3D9D A;  4P13 A;  1EGC A;  3S7W A;  3UU9 A;  2REH A;  3GM6 A;  3AFE A;  4M9A A;  2E81 A;  4L3X A;  2UXW A;  4X28 A;  2VIG A;  4Q0T A;  2FON A;  5K3I A;  2RFQ A;  2Z1Q A;  1U8V A;  2E80 A;  3SCE A;  3LG1 A;  4L38 A;  2C0U A;  1W07 A;  2JBT A;  2WBI A;  1WS9 A;  2JBS A;  4JEK A;  1IVH A;  4L3Z A;  3AFF A;  2VR0 A;  4Q4U A;  1UDY A;  3II9 A;  4U83 A;  3PFD A;  3L1T A;  2YYG A;  3MMO A;  1UKW A; 
#chains in the Genus database with same CATH topology
 3R7K A;  2ZKJ A;  2FP2 A;  1FS7 A;  4FF1 A;  3MXL A;  4H85 A;  5M4N A;  4MP7 A;  4Q5B A;  3LGQ A;  2E0A A;  2OEV A;  3UBR A;  3SWO A;  2IX6 A;  2YYM A;  3F29 A;  2OJQ A;  2XS1 A;  1EGE A;  3TZ5 A;  3C2P A;  4G5E A;  1XFZ A;  2YYI A;  4Q1O A;  3TZ2 A;  1SIR A;  5EZ3 A;  4HR3 A;  3GQT A;  2YGW A;  1T9G A;  4ZYJ A;  4KCF A;  3HWC A;  4HKS A;  3SXQ A;  3DJL A;  1IS2 A;  3TTB A;  1X90 A;  3TZ4 A;  1SK6 A;  2R0M A;  4NXL A;  5BRM A;  1OAH A;  1Y8O A;  3D9F A;  3CRK A;  3B96 A;  2BU7 A;  2CJ5 A;  4DZY A;  5K3G A;  4LQS B;  2ZDY A;  2BU2 A;  2OEX A;  4Q5C A;  1JQI A;  2DVL A;  2EC5 A;  1EGD A;  3GNC A;  4MP2 A;  2FP1 A;  2DDH A;  3VAD A;  3MDD A;  2D29 A;  3D9G A;  4IRN A;  4WJY A;  3X29 A;  2BU5 A;  1SIQ A;  3C3L A;  1BUC A;  2R02 A;  2OR0 A;  2ZAF A;  2PO4 A;  3OIB A;  3BNG A;  3OWM A;  4OO2 A;  3VKH A;  3D9E A;  3U33 A;  2ZDX A;  2IX5 A;  3MPJ A;  2C12 A;  1GU6 A;  2YYL A;  2Q8H A;  3EOM A;  2Q8F A;  3TOR A;  5J6A A;  3SF6 A;  3MMO A;  4N5F A;  2JBR A;  3MDE A;  1Y0V A;  2RF7 A;  4DOY A;  1K93 A;  1Y8N A;  2PNR A;  2CJ8 A;  3D2R A;  3C46 A;  3FCJ A;  2CX9 A;  1GKZ A;  1QDB A;  5K3J A;  2J7A A;  2AZE A;  5J71 A;  2EBH X;  2EBF X;  3BNH A;  4P79 A;  4X28 C;  2CJ7 A;  5GJW E;  5B5V A;  5B5W A;  4F0X A;  2RDZ A;  4IV6 A;  2VF1 A;  1JM6 A;  4L1F A;  3P4T A;  4XVX A;  1S26 A;  4E01 A;  3N0R A;  5K3H A;  4KS9 A;  4FF4 A;  1PK0 A;  5M4K A;  5BRK A;  2HJN A;  2R0N A;  1X91 A;  1XFU A;  4AKG A;  1FS9 A;  2LFW A;  2BU8 A;  2CJ4 A;  2OT4 A;  2EBA A;  3M9V A;  5M4M A;  4ZXV A;  2YYJ A;  1Y8P A;  1XFW A;  2XS8 A;  2PG0 A;  3OWA A;  1RJ4 A;  2ZO5 A;  4JIO A;  4Q17 A;  3Q24 A;  3VKG A;  1X8Z A;  3RKH A;  2Q8G A;  2A1T A;  1RX0 A;  1PI1 A;  4KSA A;  4FF3 A;  4KSF A;  3X0Y A;  2YYK A;  3TZ0 A;  4HKR A;  3MKH A;  1R2J A;  2BU6 A;  2F6L A;  4W9U A;  1FS8 A;  3D6B A;  4RM7 A;  1RJ1 A;  3BNF A;  3BNJ A;  2JIF A;  3MPI A;  5GJV E;  3NF4 A;  4QIC A;  1GJV A;  4L3Y A;  1XFV A;  4O5M A;  3D1I A;  2AO2 A;  3CRL A;  3X0X A;  4LQQ B;  4KTO A;  1XG2 B;  2GBB A;  4V25 A;  3FO3 A;  3EON A;  4AKH A;  3D9D A;  4P13 A;  4AKI A;  1EGC A;  4FZ4 A;  3S7W A;  3UU9 A;  2REH A;  1LVC A;  2BTZ A;  4MPC A;  3Q22 A;  5B6B A;  3GM6 A;  3Q23 A;  3AFE A;  1R3B A;  3KML A;  4V26 A;  4M9A A;  2E81 A;  4H7Q A;  4L3X A;  2UXW A;  4X28 A;  2VIG A;  4Q0T A;  4FF2 A;  2FON A;  5K3I A;  1K90 A;  2RFQ A;  2Z1Q A;  1U8V A;  2E80 A;  3SCE A;  3LG1 A;  2R03 A;  4L38 A;  3Q0A A;  1XFX A;  4G97 A;  2C0U A;  1W07 A;  2JBT A;  2WBI A;  1XFY A;  1K8T A;  1WS9 A;  2CJ6 A;  3CE2 A;  1GKX A;  4E00 A;  4AI6 A;  2JBS A;  4MPE A;  4MPN A;  4JEK A;  5M4P A;  1IVH A;  2Q8I A;  4JIZ A;  4L3Z A;  1SC5 A;  4J1V A;  3AFF A;  2R05 A;  2VR0 A;  4Q4U A;  1UDY A;  2QR4 A;  3II9 A;  4U83 A;  3PFD A;  1RP3 A;  3L1T A;  4H81 A;  4E02 A;  2YYG A;  2XQR B;  1UKW A; 
#chains in the Genus database with same CATH homology
 3R7K A;  1FS7 A;  3MXL A;  4Q5B A;  3LGQ A;  3UBR A;  3SWO A;  2IX6 A;  2YYM A;  3F29 A;  1EGE A;  4G5E A;  2YYI A;  4Q1O A;  1SIR A;  4HR3 A;  3GQT A;  1T9G A;  4ZYJ A;  4KCF A;  3HWC A;  3SXQ A;  1IS2 A;  3TTB A;  2R0M A;  4NXL A;  1OAH A;  3D9F A;  3B96 A;  5K3G A;  4Q5C A;  1JQI A;  2DVL A;  1EGD A;  3GNC A;  2DDH A;  3MDD A;  2D29 A;  3D9G A;  4IRN A;  4WJY A;  1SIQ A;  1BUC A;  2OR0 A;  2ZAF A;  3BNG A;  3OIB A;  3OWM A;  4OO2 A;  3D9E A;  2IX5 A;  3MPJ A;  2C12 A;  1GU6 A;  2YYL A;  3EOM A;  3TOR A;  3SF6 A;  4N5F A;  2JBR A;  3MDE A;  2RF7 A;  4DOY A;  3FCJ A;  2CX9 A;  1QDB A;  5K3J A;  2J7A A;  3BNH A;  4X28 C;  2RDZ A;  4IV6 A;  4L1F A;  3P4T A;  4XVX A;  5K3H A;  2R0N A;  1FS9 A;  2OT4 A;  2EBA A;  3M9V A;  4ZXV A;  2YYJ A;  2ZO5 A;  2PG0 A;  3OWA A;  4Q17 A;  3RKH A;  2A1T A;  1RX0 A;  3X0Y A;  2YYK A;  3MKH A;  1R2J A;  4W9U A;  1FS8 A;  3D6B A;  4RM7 A;  3BNF A;  3BNJ A;  2JIF A;  3MPI A;  3NF4 A;  4L3Y A;  4O5M A;  3D1I A;  3X0X A;  4KTO A;  3FO3 A;  3EON A;  3D9D A;  4P13 A;  1EGC A;  3S7W A;  3UU9 A;  2REH A;  3GM6 A;  3AFE A;  4M9A A;  2E81 A;  4L3X A;  2UXW A;  4X28 A;  2VIG A;  4Q0T A;  2FON A;  5K3I A;  2RFQ A;  2Z1Q A;  1U8V A;  2E80 A;  3SCE A;  3LG1 A;  4L38 A;  2C0U A;  1W07 A;  2JBT A;  2WBI A;  1WS9 A;  2JBS A;  4JEK A;  1IVH A;  4L3Z A;  3AFF A;  2VR0 A;  4Q4U A;  1UDY A;  3II9 A;  4U83 A;  3PFD A;  3L1T A;  2YYG A;  3MMO A;  1UKW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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