2UXWA

Crystal structure of human very long chain acyl-coa dehydrogenase (acadvl)
Total Genus 213
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
213
sequence length
587
structure length
567
Chain Sequence
QSMSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFGSGLSLSGLVHPELSRSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords VERY-LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE
publication title Crystal Structure of Human Very Long Chain Acyl- Coa Dehydrogenase (Acadvl)
rcsb
source organism Homo sapiens
molecule tags Oxidoreductase
total genus 213
structure length 567
sequence length 587
ec nomenclature ec 1.3.8.9: Very-long-chain acyl-CoA dehydrogenase.
pdb deposition date 2007-03-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 2uxwA02
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 2uxwA04
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 2uxwA01
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 2uxwA03
3L1TA 3B96A 2YYJA 1UKWA 4KCFA 2JBRA 3D6BA 2A1TA 1OAHA 2JIFA 4JEKA 4OO2A 3GNCA 2DVLA 1W07A 4Q0TA 3LGQA 4HR3A 3R7KA 4L3YA 3D9DA 3D1IA 1SIQA 3NF4A 3EONA 1RX0A 2REHA 3M9VA 3F29A 3MDDA 2VR0A 3EOMA 3OIBA 3BNJA 3AFEA 2E80A 4Q17A 1EGCA 1QDBA 5K3JA 2WBIA 3HWCA 1EGDA 2EBAA 2ZO5A 4L1FA 2UXWA 3BNHA 3AFFA 3MPJA 3OWMA 2ZAFA 1FS7A 3D9FA 1JQIA 3P4TA 2OT4A 4Q5BA 2YYMA 1UDYA 2VIGA 4RM7A 2FONA 3BNGA 4Q1OA 4IRNA 4N5FA 2IX6A 2OR0A 3TTBA 4G5EA 2JBSA 1U8VA 4KTOA 2Z1QA 2E81A 2C0UA 4WJYA 2YYLA 2RDZA 4W9UA 1T9GA 3FCJA 4O5MA 4ZYJA 1IVHA 4IV6A 2PG0A 1FS8A 3UBRA 1EGEA 3D9GA 2RFQA 3X0XA 3FO3A 3SXQA 3RKHA 2C12A 4X28A 2CX9A 3MMOA 2IX5A 3TORA 3SF6A 3MKHA 4Q5CA 2YYIA 5K3IA 1SIRA 4L38A 2R0MA 3PFDA 2D29A 3MDEA 2JBTA 3MXLA 2RF7A 4U83A 2DDHA 3LG1A 1WS9A 3SCEA 3D9EA 4X28C 1FS9A 2YYKA 1IS2A 2J7AA 4NXLA 3GQTA 4XVXA 4DOYA 1GU6A 4L3ZA 3MPIA 4P13A 3UU9A 3SWOA 3X0YA 4ZXVA 5K3GA 2R0NA 3GM6A 1R2JA 3S7WA 4M9AA 3BNFA 5K3HA 2YYGA 3II9A 3OWAA 4L3XA 4Q4UA 1BUCA
chains in the Genus database with same CATH superfamily
3L1TA 2YGWA 4AKHA 3B96A 3U33A 2YYJA 1UKWA 4KCFA 2JBRA 1GKZA 3D6BA 1X90A 4E02A 1K93A 2A1TA 1OAHA 2JIFA 4AKIA 4JEKA 4OO2A 3GNCA 2DVLA 1Y8NA 3VKGA 1W07A 4Q0TA 4AKGA 5GJWE 3LGQA 4KSFA 3C46A 3VKHA 3KMLA 4KSAA 4HR3A 3TZ4A 5BRKA 3R7KA 4HKRA 4L3YA 3CRKA 3D9DA 3D1IA 2AO2A 3Q22A 4QICA 1SIQA 3NF4A 3EONA 1XFZA 2CJ5A 3N0RA 1RX0A 2REHA 3M9VA 1XG2B 4G97A 3Q0AA 3F29A 3MDDA 2VR0A 2QR4A 4FF3A 3EOMA 4H85A 3OIBA 2CJ4A 3BNJA 3TZ0A 4E00A 3AFEA 2FP1A 2BU5A 2R03A 4J1VA 2BU7A 2E80A 3D2RA 2CJ7A 4Q17A 1EGCA 1QDBA 5K3JA 2WBIA 3HWCA 1EGDA 2EBAA 2ZO5A 4L1FA 2UXWA 3BNHA 3AFFA 3MPJA 3OWMA 2ZAFA 2Q8HA 1FS7A 3D9FA 1JQIA 3P4TA 1R3BA 2HJNA 2PO4A 2YYMA 4Q5BA 2OT4A 1K8TA 1RP3A 1UDYA 2VIGA 1XFYA 4RM7A 1Y8OA 2XQRB 3X29A 2FONA 2XS8A 3BNGA 2PNRA 4Q1OA 4IRNA 4N5FA 2IX6A 2OR0A 1X91A 2CJ6A 3TTBA 1JM6A 1XFUA 2OEXA 4G5EA 5M4NA 1SK6A 4LQSB 2JBSA 1GJVA 1U8VA 2F6LA 4KTOA 2GBBA 2Z1QA 4H81A 5M4PA 2ZKJA 2E81A 2C0UA 4V26A 1RJ1A 4WJYA 2YYLA 2RDZA 4W9UA 1T9GA 4FF1A 2OEVA 2OJQA 2BU6A 3VADA 1GKXA 1K90A 3TZ5A 4HKSA 3FCJA 1Y0VA 4E01A 4FF4A 4O5MA 4ZYJA 4JIOA 1IVHA 4IV6A 4MPNA 2PG0A 1FS8A 3UBRA 2VF1A 1EGEA 3D9GA 2RFQA 3X0XA 4MPCA 2AZEA 3FO3A 3SXQA 5EZ3A 3RKHA 2C12A 4X28A 4FF2A 2CX9A 2BU8A 3CRLA 2ZDYA 3MMOA 3C2PA 2EBHX 2IX5A 2LFWA 2EC5A 4DZYA 5J6AA 3TORA 4AI6A 3SF6A 4P79A 3MKHA 4Q5CA 2YYIA 5K3IA 1SIRA 4L38A 2R0MA 2E0AA 4FZ4A 3PFDA 5M4MA 2D29A 3MDEA 1RJ4A 2BTZA 2CJ8A 5M4KA 1XFXA 2ZDXA 3DJLA 2JBTA 3MXLA 4MP2A 3CE2A 4F0XA 3TZ2A 5B6BA 4JIZA 5BRMA 2RF7A 4U83A 1XFWA 2DDHA 2Q8GA 3LG1A 1WS9A 3SCEA 3D9EA 4X28C 1FS9A 2YYKA 1IS2A 2J7AA 2R02A 4NXLA 3Q23A 3GQTA 4XVXA 1PK0A 2Q8IA 4DOYA 3C3LA 1GU6A 4H7QA 5B5VA 2FP2A 4LQQB 1S26A 4MP7A 4L3ZA 2XS1A 3MPIA 4P13A 2R05A 3UU9A 4V25A 4KS9A 3SWOA 3X0YA 4ZXVA 5K3GA 1XFVA 2R0NA 3Q24A 3GM6A 2EBFX 5GJVE 5B5WA 1PI1A 1R2JA 3S7WA 4M9AA 1SC5A 5K3HA 3BNFA 2Q8FA 5J71A 2YYGA 1X8ZA 1Y8PA 3II9A 3OWAA 4L3XA 4Q4UA 1BUCA 1LVCA 4MPEA 2BU2A
chains in the Genus database with same CATH topology
3L1TA 3B96A 2YYJA 1UKWA 4KCFA 2JBRA 3D6BA 2A1TA 1OAHA 2JIFA 4JEKA 4OO2A 3GNCA 2DVLA 1W07A 4Q0TA 3LGQA 4HR3A 3R7KA 4L3YA 3D9DA 3D1IA 1SIQA 3NF4A 3EONA 1RX0A 2REHA 3M9VA 3F29A 3MDDA 2VR0A 3EOMA 3OIBA 3BNJA 3AFEA 2E80A 4Q17A 1EGCA 1QDBA 5K3JA 2WBIA 3HWCA 1EGDA 2EBAA 2ZO5A 4L1FA 2UXWA 3BNHA 3AFFA 3MPJA 3OWMA 2ZAFA 1FS7A 3D9FA 1JQIA 3P4TA 2OT4A 4Q5BA 2YYMA 1UDYA 2VIGA 4RM7A 2FONA 3BNGA 4Q1OA 4IRNA 4N5FA 2IX6A 2OR0A 3TTBA 4G5EA 2JBSA 1U8VA 4KTOA 2Z1QA 2E81A 2C0UA 4WJYA 2YYLA 2RDZA 4W9UA 1T9GA 3FCJA 4O5MA 4ZYJA 1IVHA 4IV6A 2PG0A 1FS8A 3UBRA 1EGEA 3D9GA 2RFQA 3X0XA 3FO3A 3SXQA 3RKHA 2C12A 4X28A 2CX9A 3MMOA 2IX5A 3TORA 3SF6A 3MKHA 4Q5CA 2YYIA 5K3IA 1SIRA 4L38A 2R0MA 3PFDA 2D29A 3MDEA 2JBTA 3MXLA 2RF7A 4U83A 2DDHA 3LG1A 1WS9A 3SCEA 3D9EA 4X28C 1FS9A 2YYKA 1IS2A 2J7AA 4NXLA 3GQTA 4XVXA 4DOYA 1GU6A 4L3ZA 3MPIA 4P13A 3UU9A 3SWOA 3X0YA 4ZXVA 5K3GA 2R0NA 3GM6A 1R2JA 3S7WA 4M9AA 3BNFA 5K3HA 2YYGA 3II9A 3OWAA 4L3XA 4Q4UA 1BUCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3L1T A;  3B96 A;  2YYJ A;  1UKW A;  4KCF A;  2JBR A;  3D6B A;  2A1T A;  1OAH A;  2JIF A;  4JEK A;  4OO2 A;  3GNC A;  2DVL A;  1W07 A;  4Q0T A;  3LGQ A;  4HR3 A;  3R7K A;  4L3Y A;  3D9D A;  3D1I A;  1SIQ A;  3NF4 A;  3EON A;  1RX0 A;  2REH A;  3M9V A;  3F29 A;  3MDD A;  2VR0 A;  3EOM A;  3OIB A;  3BNJ A;  3AFE A;  2E80 A;  4Q17 A;  1EGC A;  1QDB A;  5K3J A;  2WBI A;  3HWC A;  1EGD A;  2EBA A;  2ZO5 A;  4L1F A;  2UXW A;  3BNH A;  3AFF A;  3MPJ A;  3OWM A;  2ZAF A;  1FS7 A;  3D9F A;  1JQI A;  3P4T A;  2OT4 A;  4Q5B A;  2YYM A;  1UDY A;  2VIG A;  4RM7 A;  2FON A;  3BNG A;  4Q1O A;  4IRN A;  4N5F A;  2IX6 A;  2OR0 A;  3TTB A;  4G5E A;  2JBS A;  1U8V A;  4KTO A;  2Z1Q A;  2E81 A;  2C0U A;  4WJY A;  2YYL A;  2RDZ A;  4W9U A;  1T9G A;  3FCJ A;  4O5M A;  4ZYJ A;  1IVH A;  4IV6 A;  2PG0 A;  1FS8 A;  3UBR A;  1EGE A;  3D9G A;  2RFQ A;  3X0X A;  3FO3 A;  3SXQ A;  3RKH A;  2C12 A;  4X28 A;  2CX9 A;  3MMO A;  2IX5 A;  3TOR A;  3SF6 A;  3MKH A;  4Q5C A;  2YYI A;  5K3I A;  1SIR A;  4L38 A;  2R0M A;  3PFD A;  2D29 A;  3MDE A;  2JBT A;  3MXL A;  2RF7 A;  4U83 A;  2DDH A;  3LG1 A;  1WS9 A;  3SCE A;  3D9E A;  4X28 C;  1FS9 A;  2YYK A;  1IS2 A;  2J7A A;  4NXL A;  3GQT A;  4XVX A;  4DOY A;  1GU6 A;  4L3Z A;  3MPI A;  4P13 A;  3UU9 A;  3SWO A;  3X0Y A;  4ZXV A;  5K3G A;  2R0N A;  3GM6 A;  1R2J A;  3S7W A;  4M9A A;  3BNF A;  5K3H A;  2YYG A;  3II9 A;  3OWA A;  4L3X A;  4Q4U A;  1BUC A; 
#chains in the Genus database with same CATH topology
 3L1T A;  2YGW A;  4AKH A;  3B96 A;  3U33 A;  2YYJ A;  1UKW A;  4KCF A;  2JBR A;  1GKZ A;  3D6B A;  1X90 A;  4E02 A;  1K93 A;  2A1T A;  1OAH A;  2JIF A;  4AKI A;  4JEK A;  4OO2 A;  3GNC A;  2DVL A;  1Y8N A;  3VKG A;  1W07 A;  4Q0T A;  4AKG A;  5GJW E;  3LGQ A;  4KSF A;  3C46 A;  3VKH A;  3KML A;  4KSA A;  4HR3 A;  3TZ4 A;  5BRK A;  3R7K A;  4HKR A;  4L3Y A;  3CRK A;  3D9D A;  3D1I A;  2AO2 A;  3Q22 A;  4QIC A;  1SIQ A;  3NF4 A;  3EON A;  1XFZ A;  2CJ5 A;  3N0R A;  1RX0 A;  2REH A;  3M9V A;  1XG2 B;  4G97 A;  3Q0A A;  3F29 A;  3MDD A;  2VR0 A;  2QR4 A;  4FF3 A;  3EOM A;  4H85 A;  3OIB A;  2CJ4 A;  3BNJ A;  3TZ0 A;  4E00 A;  3AFE A;  2FP1 A;  2BU5 A;  2R03 A;  4J1V A;  2BU7 A;  2E80 A;  3D2R A;  2CJ7 A;  4Q17 A;  1EGC A;  1QDB A;  5K3J A;  2WBI A;  3HWC A;  1EGD A;  2EBA A;  2ZO5 A;  4L1F A;  2UXW A;  3BNH A;  3AFF A;  3MPJ A;  3OWM A;  2ZAF A;  2Q8H A;  1FS7 A;  3D9F A;  1JQI A;  3P4T A;  1R3B A;  2HJN A;  2PO4 A;  2YYM A;  4Q5B A;  2OT4 A;  1K8T A;  1RP3 A;  1UDY A;  2VIG A;  1XFY A;  4RM7 A;  1Y8O A;  2XQR B;  3X29 A;  2FON A;  2XS8 A;  3BNG A;  2PNR A;  4Q1O A;  4IRN A;  4N5F A;  2IX6 A;  2OR0 A;  1X91 A;  2CJ6 A;  3TTB A;  1JM6 A;  1XFU A;  2OEX A;  4G5E A;  5M4N A;  1SK6 A;  4LQS B;  2JBS A;  1GJV A;  1U8V A;  2F6L A;  4KTO A;  2GBB A;  2Z1Q A;  4H81 A;  5M4P A;  2ZKJ A;  2E81 A;  2C0U A;  4V26 A;  1RJ1 A;  4WJY A;  2YYL A;  2RDZ A;  4W9U A;  1T9G A;  4FF1 A;  2OEV A;  2OJQ A;  2BU6 A;  3VAD A;  1GKX A;  1K90 A;  3TZ5 A;  4HKS A;  3FCJ A;  1Y0V A;  4E01 A;  4FF4 A;  4O5M A;  4ZYJ A;  4JIO A;  1IVH A;  4IV6 A;  4MPN A;  2PG0 A;  1FS8 A;  3UBR A;  2VF1 A;  1EGE A;  3D9G A;  2RFQ A;  3X0X A;  4MPC A;  2AZE A;  3FO3 A;  3SXQ A;  5EZ3 A;  3RKH A;  2C12 A;  4X28 A;  4FF2 A;  2CX9 A;  2BU8 A;  3CRL A;  2ZDY A;  3MMO A;  3C2P A;  2EBH X;  2IX5 A;  2LFW A;  2EC5 A;  4DZY A;  5J6A A;  3TOR A;  4AI6 A;  3SF6 A;  4P79 A;  3MKH A;  4Q5C A;  2YYI A;  5K3I A;  1SIR A;  4L38 A;  2R0M A;  2E0A A;  4FZ4 A;  3PFD A;  5M4M A;  2D29 A;  3MDE A;  1RJ4 A;  2BTZ A;  2CJ8 A;  5M4K A;  1XFX A;  2ZDX A;  3DJL A;  2JBT A;  3MXL A;  4MP2 A;  3CE2 A;  4F0X A;  3TZ2 A;  5B6B A;  4JIZ A;  5BRM A;  2RF7 A;  4U83 A;  1XFW A;  2DDH A;  2Q8G A;  3LG1 A;  1WS9 A;  3SCE A;  3D9E A;  4X28 C;  1FS9 A;  2YYK A;  1IS2 A;  2J7A A;  2R02 A;  4NXL A;  3Q23 A;  3GQT A;  4XVX A;  1PK0 A;  2Q8I A;  4DOY A;  3C3L A;  1GU6 A;  4H7Q A;  5B5V A;  2FP2 A;  4LQQ B;  1S26 A;  4MP7 A;  4L3Z A;  2XS1 A;  3MPI A;  4P13 A;  2R05 A;  3UU9 A;  4V25 A;  4KS9 A;  3SWO A;  3X0Y A;  4ZXV A;  5K3G A;  1XFV A;  2R0N A;  3Q24 A;  3GM6 A;  2EBF X;  5GJV E;  5B5W A;  1PI1 A;  1R2J A;  3S7W A;  4M9A A;  1SC5 A;  5K3H A;  3BNF A;  2Q8F A;  5J71 A;  2YYG A;  1X8Z A;  1Y8P A;  3II9 A;  3OWA A;  4L3X A;  4Q4U A;  1BUC A;  1LVC A;  4MPE A;  2BU2 A; 
#chains in the Genus database with same CATH homology
 3L1T A;  3B96 A;  2YYJ A;  1UKW A;  4KCF A;  2JBR A;  3D6B A;  2A1T A;  1OAH A;  2JIF A;  4JEK A;  4OO2 A;  3GNC A;  2DVL A;  1W07 A;  4Q0T A;  3LGQ A;  4HR3 A;  3R7K A;  4L3Y A;  3D9D A;  3D1I A;  1SIQ A;  3NF4 A;  3EON A;  1RX0 A;  2REH A;  3M9V A;  3F29 A;  3MDD A;  2VR0 A;  3EOM A;  3OIB A;  3BNJ A;  3AFE A;  2E80 A;  4Q17 A;  1EGC A;  1QDB A;  5K3J A;  2WBI A;  3HWC A;  1EGD A;  2EBA A;  2ZO5 A;  4L1F A;  2UXW A;  3BNH A;  3AFF A;  3MPJ A;  3OWM A;  2ZAF A;  1FS7 A;  3D9F A;  1JQI A;  3P4T A;  2OT4 A;  4Q5B A;  2YYM A;  1UDY A;  2VIG A;  4RM7 A;  2FON A;  3BNG A;  4Q1O A;  4IRN A;  4N5F A;  2IX6 A;  2OR0 A;  3TTB A;  4G5E A;  2JBS A;  1U8V A;  4KTO A;  2Z1Q A;  2E81 A;  2C0U A;  4WJY A;  2YYL A;  2RDZ A;  4W9U A;  1T9G A;  3FCJ A;  4O5M A;  4ZYJ A;  1IVH A;  4IV6 A;  2PG0 A;  1FS8 A;  3UBR A;  1EGE A;  3D9G A;  2RFQ A;  3X0X A;  3FO3 A;  3SXQ A;  3RKH A;  2C12 A;  4X28 A;  2CX9 A;  3MMO A;  2IX5 A;  3TOR A;  3SF6 A;  3MKH A;  4Q5C A;  2YYI A;  5K3I A;  1SIR A;  4L38 A;  2R0M A;  3PFD A;  2D29 A;  3MDE A;  2JBT A;  3MXL A;  2RF7 A;  4U83 A;  2DDH A;  3LG1 A;  1WS9 A;  3SCE A;  3D9E A;  4X28 C;  1FS9 A;  2YYK A;  1IS2 A;  2J7A A;  4NXL A;  3GQT A;  4XVX A;  4DOY A;  1GU6 A;  4L3Z A;  3MPI A;  4P13 A;  3UU9 A;  3SWO A;  3X0Y A;  4ZXV A;  5K3G A;  2R0N A;  3GM6 A;  1R2J A;  3S7W A;  4M9A A;  3BNF A;  5K3H A;  2YYG A;  3II9 A;  3OWA A;  4L3X A;  4Q4U A;  1BUC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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