2UZSA

A transforming mutation in the pleckstrin homology domain of akt1 in cancer (akt1-ph_e17k)
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
117
structure length
117
Chain Sequence
SMSDVAIVKEGWLHKRGKYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords RAC-alpha serine/threonine-protein kinase
publication title A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 32
structure length 117
sequence length 117
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2007-05-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 2uzsA00
3SO6A 5C5BA 4HDQA 5KCVA 5D3WA 3GYOA 3DXDA 1MAIA 3V5WA 4DX8A 5JP4A 2Z0PA 3MDBC 1I7AA 4CHJA 1WG7A 1K5GB 2P0HA 4DBBA 4C0AA 3SNHA 2ELAA 1MPHA 1UPQA 5HE2A 4A6KA 1U5EA 2DTCA 2H7DA 3A8QA 3ZVRA 2DX5A 2DYNA 4HAXB 2AEHA 3G9WA 2I1JA 5D27A 1KI1B 3PVUA 5JHGA 4EJNA 2OTXA 5D3XA 1WJ1A 1KZGA 3P6AA 4GXBA 2COAA 2UZSA 1NU2A 1MIZB 2KUPA 1W1GA 1UNRA 4K2PA 3KSYA 3SV1A 2YS5A 2H7EA 4HHVA 1V5PA 1B55A 2AL6A 2ZPYA 1M7EA 1TQZA 3F5RA 1WGQA 2RGNB 1FGZA 3ODXA 2W2XD 1GG3A 4HAUB 2P0DA 1ZM0A 1ZVRA 2P8VA 4CHMA 2D11A 4KHOA 3TO1A 2ELBA 3PP2A 1TXDA 1PLSA 1UNQA 2L2IA 1X86A 2UVMA 4BBKA 1WI1A 1MK7B 1FOEA 1NI2A 2VRWB 4A6FB 2CODA 4HDOA 3RCPA 2K00A 3ULBA 3VOQA 4D0NB 2J0MA 3FM8C 3DXEA 1P6SA 3T06A 4KVGB 2GCLA 1UNPA 1V61A 3ML4A 2M14A 2LULA 4ZRIA 2W2XC 1H4RA 4HB0B 4Z2MB 1FHWA 1FHXA 2D9YA 5JLJB 5JHHA 2Y8FA 2K2UA 4Z2NA 5FI0A 4H8SA 2R0DA 2DHKA 4MK0A 2LOZA 1SGHA 1V5MA 2RSGA 1PFJA 1LW3A 2CRFA 2RVBB 2OQBA 1XCGA 5FI1A 3QWMA 4B6HA 2D9VA 1N3HA 2EJ8A 2DHIA 2RUKB 2CY4A 3HQCA 4HB2B 2YF0A 1WVHA 4HAYB 2P0FA 3AU4A 1X05A 3ODWA 2I1KA 5CLQB 2HE7A 1XR0B 5D3YA 1LB1A 4GZUA 3BJIA 4WVFB 5C6RA 3PVWA 2HTHB 2Q13A 1AWEA 4TYZA 3KY9A 2I5FA 5DHFB 4F7HA 3DXCA 5HE1A 2XQNM 3D8EA 2N0YA 3LJUX 3D8FA 4ZRKA 3CIKA 2EC1A 4EKUA 1W1DA 1U5GA 5EFXA 1QC6A 4YL8A 5GOWB 3U7DA 2L1CA 3U8ZA 3TFMA 2I5CA 2MFQA 4KHBB 2IYBA 2E2XA 5HE0A 2LKOA 4ZRJA 5C5BB 4XWXA 4IOYX 1E5WA 1U5DA 1TJ6A 3A98B 4KHAA 4F7UP 4HB3B 1MKEA 1FHOA 4K81A 2GCJA 2MDXA 2EMTA 2YT0A 4IAPA 2YS1A 2GS0A 2DLWA 3PEGA 2EMSA 2JP2A 1DDVA 3QIJA 4A6HA 1Z87A 5LONB 2J0JA 4GMVA 1WJMA 2CAYA 4F7GA 5LOPB 2ROVA 4K17A 2D9XA 2DN6A 2W2WA 4KAXB 2YVCA 4DXAB 4L6EA 4MY6A 1WGUA 3ULCA 3IVFA 3VIAA 1RJ2A 2D9ZA 2IFSA 1Q67A 3N7CA 3NSUA 2DFKA 1NTYA 2DYQA 2MWNB 5HE3A 2KGXB 2J0KA 4WJ7A 1P5TA 1M7RA 1FGYA 2YRYA 1QQGA 3FEHA 3SYXA 1RRPB 3O96A 1ZC3B 5DHAB 1W1HA 3TW1A 2VKIA 1ISNA 2Y7BA 4PQ0A 3F0WA 2D9WA 4HAVB 2M38A 1EF1A 1U29A 4HATB 5CLLB 1GC7A 1MIXA 4MT7A 1X1GA 5DH9B 3AU5A 2DX1A 4GMXB 3A8PA 2MKRA 1FB8A 3ODOA 2NMBA 2FJLA 2RNRB 1FAOA 1U5FA 2KCJA 2Z0OA 1BAKA 2COCA 1EAZA 5KQ1A 4HB4B 5C79A 2G35A 1DDMA 1AQCA 3QBVB 1SHCA 1V88A 3M1IB 4HAWB 3BINA 1IRSA 1DROA 3HW2B 1BWNA 2QKLA 1U27A 3ZDTA 3KZ1A 3PSCA 2CY5A 4A6FA 3KRWA 1EGXA 1ZC4B 1ZSQA 5KQ4A 2D4QA 1EVHA 1OMWA 4Y94A 2PZ1A 2DKQA 2QKMA 3HK0A 1KZ7A 1Y19B 4PNKA 2Y8GA 3SUZA 4DX90 2YT1A 5DIFB 1U2BA 4IFSA 1OQNA 1UEFA 1V5UA 4HAZB 4NY0A 2ROZB 3TCAA 1OY2A 1BTKA 1DYNA 2D2QA 1Y5OA 3FSSA 2K2JA 4WSFA 1J19A 3PZDA 5J3YA 2D10A 3CXBB 3MPXA 4P7IA 3UZTA 3TVVA 2N23A 4EMOA 2DKPA 2X18A 3KRXA 5J3TA 5C16A 3P7ZA 2VSZA 3AJ4A 2RLOA 2YS3A 1NTVA 5DI9B 1XODA 3PVLA 3PG7A 1P3RA 1DBHA 2LYDA 1XKEA 1X1FA 4A5KA 2R09A 1BTNA 3WA0A 2LOXA 3OANA 1PMSA 3WYFB 2UZRA 3X23A 1UPRA 4CYEA 1MK9B 1V89A 2J59M 1X11A 5L81A 1XD4A 4TKNA 2ADZA 2Z0QA 2BCJA 4K2OA 2COFA 2NZ8B 2LG1A 2DHJA 1XX0A 2DA0A 5J3QA 5D3VA 2GJYA 2V76A 3GYPA 1GC6A 1J0WA 1DDWA 3D8DA 4YONA 4GN1A 1I2HA 4NSWA 4GPTB 1K5DB 1H10A 2YSZA
chains in the Genus database with same CATH superfamily
3SO6A 5C5BA 4HDQA 5KCVA 5D3WA 3GYOA 3DXDA 1MAIA 3V5WA 4DX8A 5JP4A 2Z0PA 3MDBC 1I7AA 4CHJA 1WG7A 1K5GB 2P0HA 2R2YA 4DBBA 4C0AA 3SNHA 2ELAA 1MPHA 1UPQA 3A58A 5HE2A 4A6KA 1U5EA 2DTCA 2H7DA 3A8QA 3ZVRA 2DX5A 2DYNA 4HAXB 2AEHA 1MI1A 3G9WA 2I1JA 5D27A 1KI1B 3PVUA 5JHGA 4EJNA 3HIEA 4D6WA 2OTXA 5D3XA 1WJ1A 1KZGA 3P6AA 4GXBA 2Z14A 2COAA 2UZSA 1NU2A 1MIZB 2KUPA 1W1GA 1UNRA 4K2PA 3KSYA 3SV1A 2YS5A 2H7EA 4HHVA 1V5PA 1B55A 1ZYIA 2AL6A 2ZPYA 1M7EA 1TQZA 3F5RA 1WGQA 2RGNB 1FGZA 3ODXA 2W2XD 1GG3A 4HAUB 4GNKB 2P0DA 1ZM0A 1ZVRA 2P8VA 4CHMA 2D11A 4KHOA 3TO1A 2ELBA 3PP2A 1TXDA 1PLSA 1UNQA 4HSIA 2L2IA 4CSQA 1X86A 2UVMA 4BBKA 1WI1A 1MK7B 1FOEA 1NI2A 2VRWB 4A6FB 2CODA 4HDOA 3RCPA 2K00A 2KR0A 3ULBA 3B77A 3VOQA 4D0NB 2J0MA 3FM8C 3NW8A 3DXEA 1P6SA 2YT2A 3T06A 4KVGB 2GCLA 1UNPA 1V61A 3ML4A 2M14A 2LULA 4ZRIA 2W2XC 1H4RA 4HB0B 4Z2MB 1FHWA 1FHXA 4OT1A 2D9YA 5JLJB 5JHHA 2Y8FA 2K2UA 4Z2NA 5FI0A 4H8SA 4KHBA 2R0DA 2DHKA 4MK0A 2LOZA 1SGHA 1V5MA 2RSGA 1PFJA 1LW3A 2CRFA 2RVBB 2OQBA 1XCGA 5FI1A 3QWMA 4B6HA 5LG4B 2D9VA 1N3HA 2EJ8A 2DHIA 2RUKB 2CY4A 3HQCA 4HB2B 2YF0A 1WVHA 4HAYB 2P0FA 4QJ3B 3AU4A 1X05A 3DCXA 3ODWA 2I1KA 5CLQB 2HE7A 1XR0B 5D3YA 1LB1A 4GZUA 3BJIA 5M4YB 3HSAA 4WVFB 5C6RA 3PVWA 2HTHB 2Q13A 1AWEA 4TYZA 3KY9A 2I5FA 5DHFB 4F7HA 3DXCA 5HE1A 2XQNM 3D8EA 2N0YA 2GUMA 3LJUX 3D8FA 4ZRKA 3CIKA 5I2MA 2EC1A 4EKUA 1W1DA 1U5GA 5EFXA 1QC6A 4YL8A 5GOWB 3U7DA 2L1CA 3U8ZA 2Z4DA 3TFMA 2I5CA 2MFQA 4KHBB 2IYBA 2E2XA 5HE0A 2LKOA 4ZRJA 5C5BB 4XWXA 4QJ4B 2KIEA 4IOYX 1E5WA 1U5DA 1TJ6A 3A98B 4KHAA 4F7UP 4HB3B 1MKEA 1FHOA 3OHMB 4K81A 2GCJA 2MDXA 2EMTA 2YT0A 4IAPA 2YS1A 2GS0A 2DLWA 3PEGA 2EMSA 2JP2A 1DDVA 3QIJA 4A6HA 1Z87A 5LONB 2J0JA 4GMVA 1WJMA 2CAYA 4F7GA 5LOPB 2ROVA 4K17A 2D9XA 2DN6A 3NWDA 2W2WA 4KAXB 2RRFA 2K8EA 2YVCA 4DXAB 4L6EA 4MY6A 1WGUA 3ULCA 3IVFA 3VIAA 1RJ2A 2D9ZA 4GOUA 2IFSA 1Q67A 3N7CA 3NSUA 2DFKA 1NTYA 3FVCA 2DYQA 2MWNB 5HE3A 2KGXB 2J0KA 4WJ7A 1P5TA 1M7RA 1FGYA 2YRYA 1QQGA 3FEHA 2Z13A 3SYXA 1RRPB 3O96A 1ZC3B 5DHAB 1W1HA 3TW1A 2VKIA 1ISNA 2Y7BA 4PQ0A 3F0WA 2D9WA 4HAVB 2M38A 1EF1A 1U29A 4HATB 5CLLB 1GC7A 1MIXA 2NBVA 4MT7A 1X1GA 5DH9B 3AU5A 2DX1A 4GMXB 3A8PA 2MKRA 1FB8A 3ODOA 2NMBA 2FJLA 2RNRB 1FAOA 1U5FA 2KCJA 2Z0OA 1BAKA 4L1RA 2COCA 1EAZA 5KQ1A 2ZKMX 4HB4B 4OSNA 5C79A 2G35A 1DDMA 1AQCA 2KUQA 3QBVB 1SHCA 1V88A 3M1IB 4HAWB 2KIGA 3BINA 1IRSA 1DROA 3HW2B 1BWNA 3NWFA 2QKLA 1U27A 3ZDTA 3KZ1A 3PSCA 2CY5A 4A6FA 3KRWA 1EGXA 1ZC4B 1ZSQA 5KQ4A 2FJUB 2D4QA 1EVHA 1OMWA 4Y94A 2PZ1A 2DKQA 2QKMA 3HK0A 1KZ7A 4QXAB 1Y19B 4PNKA 2Y8GA 3SUZA 4DX90 2YT1A 5DIFB 1U2BA 4IFSA 3NWAA 1OQNA 1UEFA 1V5UA 4HAZB 4NY0A 2ROZB 3TCAA 1OY2A 1BTKA 1DYNA 2D2QA 1Y5OA 3FSSA 4QJ5B 2K2JA 4WSFA 1J19A 3PZDA 5J3YA 2D10A 3CXBB 3MPXA 4P7IA 3UZTA 3TVVA 2N23A 4EMOA 2DKPA 2X18A 3KRXA 5J3TA 2K49A 5C16A 3P7ZA 2VSZA 3AJ4A 2RLOA 2YS3A 1NTVA 5DI9B 1XODA 3PG7A 3PVLA 1P3RA 1DBHA 1T77A 2LYDA 1XKEA 1X1FA 4A5KA 5I2SA 2R09A 1BTNA 3WA0A 3U12A 2LOXA 3OANA 1PMSA 3WYFB 2UZRA 3X23A 1UPRA 4CYEA 1MK9B 1V89A 2J59M 5IRSA 1X11A 5L81A 1XD4A 4TKNA 2ADZA 2Z0QA 2BCJA 4K2OA 2COFA 2NZ8B 2LG1A 2DHJA 1XX0A 2DA0A 5J3QA 5D3VA 2GJYA 2V76A 3GYPA 1GC6A 1J0WA 1DDWA 3D8DA 4YONA 2Z59A 4GN1A 1I2HA 4NSWA 4GPTB 4DIXA 1K5DB 1H10A 2YSZA
chains in the Genus database with same CATH topology
3SO6A 5C5BA 4HDQA 5KCVA 5D3WA 3GYOA 3DXDA 1MAIA 3V5WA 4DX8A 5JP4A 2Z0PA 3MDBC 1I7AA 4CHJA 1WG7A 1K5GB 2P0HA 4DBBA 4C0AA 3SNHA 2ELAA 1MPHA 1UPQA 5HE2A 4A6KA 1U5EA 2DTCA 2H7DA 3A8QA 3ZVRA 2DX5A 2DYNA 4HAXB 2AEHA 3G9WA 2I1JA 5D27A 1KI1B 3PVUA 5JHGA 4EJNA 2OTXA 5D3XA 1WJ1A 1KZGA 3P6AA 4GXBA 2COAA 2UZSA 1NU2A 1MIZB 2KUPA 1W1GA 1UNRA 4K2PA 3KSYA 3SV1A 2YS5A 2H7EA 4HHVA 1V5PA 1B55A 2AL6A 2ZPYA 1M7EA 1TQZA 3F5RA 1WGQA 2RGNB 1FGZA 3ODXA 2W2XD 1GG3A 4HAUB 2P0DA 1ZM0A 1ZVRA 2P8VA 4CHMA 2D11A 4KHOA 3TO1A 2ELBA 3PP2A 1TXDA 1PLSA 1UNQA 2L2IA 1X86A 2UVMA 4BBKA 1WI1A 1MK7B 1FOEA 1NI2A 2VRWB 4A6FB 2CODA 4HDOA 3RCPA 2K00A 3ULBA 3VOQA 4D0NB 2J0MA 3FM8C 3DXEA 1P6SA 3T06A 4KVGB 2GCLA 1UNPA 1V61A 3ML4A 2M14A 2LULA 4ZRIA 2W2XC 1H4RA 4HB0B 4Z2MB 1FHWA 1FHXA 2D9YA 5JLJB 5JHHA 2Y8FA 2K2UA 4Z2NA 5FI0A 4H8SA 2R0DA 2DHKA 4MK0A 2LOZA 1SGHA 1V5MA 2RSGA 1PFJA 1LW3A 2CRFA 2RVBB 2OQBA 1XCGA 5FI1A 3QWMA 4B6HA 2D9VA 1N3HA 2EJ8A 2DHIA 2RUKB 2CY4A 3HQCA 4HB2B 2YF0A 1WVHA 4HAYB 2P0FA 3AU4A 1X05A 3ODWA 2I1KA 5CLQB 2HE7A 1XR0B 5D3YA 1LB1A 4GZUA 3BJIA 4WVFB 5C6RA 3PVWA 2HTHB 2Q13A 1AWEA 4TYZA 3KY9A 2I5FA 5DHFB 4F7HA 3DXCA 5HE1A 2XQNM 3D8EA 2N0YA 3LJUX 3D8FA 4ZRKA 3CIKA 2EC1A 4EKUA 1W1DA 1U5GA 5EFXA 1QC6A 4YL8A 5GOWB 3U7DA 2L1CA 3U8ZA 3TFMA 2I5CA 2MFQA 4KHBB 2IYBA 2E2XA 5HE0A 2LKOA 4ZRJA 5C5BB 4XWXA 4IOYX 1E5WA 1U5DA 1TJ6A 3A98B 4KHAA 4F7UP 4HB3B 1MKEA 1FHOA 4K81A 2GCJA 2MDXA 2EMTA 2YT0A 4IAPA 2YS1A 2GS0A 2DLWA 3PEGA 2EMSA 2JP2A 1DDVA 3QIJA 4A6HA 1Z87A 5LONB 2J0JA 4GMVA 1WJMA 2CAYA 4F7GA 5LOPB 2ROVA 4K17A 2D9XA 2DN6A 2W2WA 4KAXB 2YVCA 4DXAB 4L6EA 4MY6A 1WGUA 3ULCA 3IVFA 3VIAA 1RJ2A 2D9ZA 2IFSA 1Q67A 3N7CA 3NSUA 2DFKA 1NTYA 2DYQA 2MWNB 5HE3A 2KGXB 2J0KA 4WJ7A 1P5TA 1M7RA 1FGYA 2YRYA 1QQGA 3FEHA 3SYXA 1RRPB 3O96A 1ZC3B 5DHAB 1W1HA 3TW1A 2VKIA 1ISNA 2Y7BA 4PQ0A 3F0WA 2D9WA 4HAVB 2M38A 1EF1A 1U29A 4HATB 5CLLB 1GC7A 1MIXA 4MT7A 1X1GA 5DH9B 3AU5A 2DX1A 4GMXB 3A8PA 2MKRA 1FB8A 3ODOA 2NMBA 2FJLA 2RNRB 1FAOA 1U5FA 2KCJA 2Z0OA 1BAKA 2COCA 1EAZA 5KQ1A 4HB4B 5C79A 2G35A 1DDMA 1AQCA 3QBVB 1SHCA 1V88A 3M1IB 4HAWB 3BINA 1IRSA 1DROA 3HW2B 1BWNA 2QKLA 1U27A 3ZDTA 3KZ1A 3PSCA 2CY5A 4A6FA 3KRWA 1EGXA 1ZC4B 1ZSQA 5KQ4A 2D4QA 1EVHA 1OMWA 4Y94A 2PZ1A 2DKQA 2QKMA 3HK0A 1KZ7A 1Y19B 4PNKA 2Y8GA 3SUZA 4DX90 2YT1A 5DIFB 1U2BA 4IFSA 1OQNA 1UEFA 1V5UA 4HAZB 4NY0A 2ROZB 3TCAA 1OY2A 1BTKA 1DYNA 2D2QA 1Y5OA 3FSSA 2K2JA 4WSFA 1J19A 3PZDA 5J3YA 2D10A 3CXBB 3MPXA 4P7IA 3UZTA 3TVVA 2N23A 4EMOA 2DKPA 2X18A 3KRXA 5J3TA 5C16A 3P7ZA 2VSZA 3AJ4A 2RLOA 2YS3A 1NTVA 5DI9B 1XODA 3PVLA 3PG7A 1P3RA 1DBHA 2LYDA 1XKEA 1X1FA 4A5KA 2R09A 1BTNA 3WA0A 2LOXA 3OANA 1PMSA 3WYFB 2UZRA 3X23A 1UPRA 4CYEA 1MK9B 1V89A 2J59M 1X11A 5L81A 1XD4A 4TKNA 2ADZA 2Z0QA 2BCJA 4K2OA 2COFA 2NZ8B 2LG1A 2DHJA 1XX0A 2DA0A 5J3QA 5D3VA 2GJYA 2V76A 3GYPA 1GC6A 1J0WA 1DDWA 3D8DA 4YONA 4GN1A 1I2HA 4NSWA 4GPTB 1K5DB 1H10A 2YSZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SO6 A;  5C5B A;  4HDQ A;  5KCV A;  5D3W A;  3GYO A;  3DXD A;  1MAI A;  3V5W A;  4DX8 A;  5JP4 A;  2Z0P A;  3MDB C;  1I7A A;  4CHJ A;  1WG7 A;  1K5G B;  2P0H A;  4DBB A;  4C0A A;  3SNH A;  2ELA A;  1MPH A;  1UPQ A;  5HE2 A;  4A6K A;  1U5E A;  2DTC A;  2H7D A;  3A8Q A;  3ZVR A;  2DX5 A;  2DYN A;  4HAX B;  2AEH A;  3G9W A;  2I1J A;  5D27 A;  1KI1 B;  3PVU A;  5JHG A;  4EJN A;  2OTX A;  5D3X A;  1WJ1 A;  1KZG A;  3P6A A;  4GXB A;  2COA A;  2UZS A;  1NU2 A;  1MIZ B;  2KUP A;  1W1G A;  1UNR A;  4K2P A;  3KSY A;  3SV1 A;  2YS5 A;  2H7E A;  4HHV A;  1V5P A;  1B55 A;  2AL6 A;  2ZPY A;  1M7E A;  1TQZ A;  3F5R A;  1WGQ A;  2RGN B;  1FGZ A;  3ODX A;  2W2X D;  1GG3 A;  4HAU B;  2P0D A;  1ZM0 A;  1ZVR A;  2P8V A;  4CHM A;  2D11 A;  4KHO A;  3TO1 A;  2ELB A;  3PP2 A;  1TXD A;  1PLS A;  1UNQ A;  2L2I A;  1X86 A;  2UVM A;  4BBK A;  1WI1 A;  1MK7 B;  1FOE A;  1NI2 A;  2VRW B;  4A6F B;  2COD A;  4HDO A;  3RCP A;  2K00 A;  3ULB A;  3VOQ A;  4D0N B;  2J0M A;  3FM8 C;  3DXE A;  1P6S A;  3T06 A;  4KVG B;  2GCL A;  1UNP A;  1V61 A;  3ML4 A;  2M14 A;  2LUL A;  4ZRI A;  2W2X C;  1H4R A;  4HB0 B;  4Z2M B;  1FHW A;  1FHX A;  2D9Y A;  5JLJ B;  5JHH A;  2Y8F A;  2K2U A;  4Z2N A;  5FI0 A;  4H8S A;  2R0D A;  2DHK A;  4MK0 A;  2LOZ A;  1SGH A;  1V5M A;  2RSG A;  1PFJ A;  1LW3 A;  2CRF A;  2RVB B;  2OQB A;  1XCG A;  5FI1 A;  3QWM A;  4B6H A;  2D9V A;  1N3H A;  2EJ8 A;  2DHI A;  2RUK B;  2CY4 A;  3HQC A;  4HB2 B;  2YF0 A;  1WVH A;  4HAY B;  2P0F A;  3AU4 A;  1X05 A;  3ODW A;  2I1K A;  5CLQ B;  2HE7 A;  1XR0 B;  5D3Y A;  1LB1 A;  4GZU A;  3BJI A;  4WVF B;  5C6R A;  3PVW A;  2HTH B;  2Q13 A;  1AWE A;  4TYZ A;  3KY9 A;  2I5F A;  5DHF B;  4F7H A;  3DXC A;  5HE1 A;  2XQN M;  3D8E A;  2N0Y A;  3LJU X;  3D8F A;  4ZRK A;  3CIK A;  2EC1 A;  4EKU A;  1W1D A;  1U5G A;  5EFX A;  1QC6 A;  4YL8 A;  5GOW B;  3U7D A;  2L1C A;  3U8Z A;  3TFM A;  2I5C A;  2MFQ A;  4KHB B;  2IYB A;  2E2X A;  5HE0 A;  2LKO A;  4ZRJ A;  5C5B B;  4XWX A;  4IOY X;  1E5W A;  1U5D A;  1TJ6 A;  3A98 B;  4KHA A;  4F7U P;  4HB3 B;  1MKE A;  1FHO A;  4K81 A;  2GCJ A;  2MDX A;  2EMT A;  2YT0 A;  4IAP A;  2YS1 A;  2GS0 A;  2DLW A;  3PEG A;  2EMS A;  2JP2 A;  1DDV A;  3QIJ A;  4A6H A;  1Z87 A;  5LON B;  2J0J A;  4GMV A;  1WJM A;  2CAY A;  4F7G A;  5LOP B;  2ROV A;  4K17 A;  2D9X A;  2DN6 A;  2W2W A;  4KAX B;  2YVC A;  4DXA B;  4L6E A;  4MY6 A;  1WGU A;  3ULC A;  3IVF A;  3VIA A;  1RJ2 A;  2D9Z A;  2IFS A;  1Q67 A;  3N7C A;  3NSU A;  2DFK A;  1NTY A;  2DYQ A;  2MWN B;  5HE3 A;  2KGX B;  2J0K A;  4WJ7 A;  1P5T A;  1M7R A;  1FGY A;  2YRY A;  1QQG A;  3FEH A;  3SYX A;  1RRP B;  3O96 A;  1ZC3 B;  5DHA B;  1W1H A;  3TW1 A;  2VKI A;  1ISN A;  2Y7B A;  4PQ0 A;  3F0W A;  2D9W A;  4HAV B;  2M38 A;  1EF1 A;  1U29 A;  4HAT B;  5CLL B;  1GC7 A;  1MIX A;  4MT7 A;  1X1G A;  5DH9 B;  3AU5 A;  2DX1 A;  4GMX B;  3A8P A;  2MKR A;  1FB8 A;  3ODO A;  2NMB A;  2FJL A;  2RNR B;  1FAO A;  1U5F A;  2KCJ A;  2Z0O A;  1BAK A;  2COC A;  1EAZ A;  5KQ1 A;  4HB4 B;  5C79 A;  2G35 A;  1DDM A;  1AQC A;  3QBV B;  1SHC A;  1V88 A;  3M1I B;  4HAW B;  3BIN A;  1IRS A;  1DRO A;  3HW2 B;  1BWN A;  2QKL A;  1U27 A;  3ZDT A;  3KZ1 A;  3PSC A;  2CY5 A;  4A6F A;  3KRW A;  1EGX A;  1ZC4 B;  1ZSQ A;  5KQ4 A;  2D4Q A;  1EVH A;  1OMW A;  4Y94 A;  2PZ1 A;  2DKQ A;  2QKM A;  3HK0 A;  1KZ7 A;  1Y19 B;  4PNK A;  2Y8G A;  3SUZ A;  4DX9 0;  2YT1 A;  5DIF B;  1U2B A;  4IFS A;  1OQN A;  1UEF A;  1V5U A;  4HAZ B;  4NY0 A;  2ROZ B;  3TCA A;  1OY2 A;  1BTK A;  1DYN A;  2D2Q A;  1Y5O A;  3FSS A;  2K2J A;  4WSF A;  1J19 A;  3PZD A;  5J3Y A;  2D10 A;  3CXB B;  3MPX A;  4P7I A;  3UZT A;  3TVV A;  2N23 A;  4EMO A;  2DKP A;  2X18 A;  3KRX A;  5J3T A;  5C16 A;  3P7Z A;  2VSZ A;  3AJ4 A;  2RLO A;  2YS3 A;  1NTV A;  5DI9 B;  1XOD A;  3PVL A;  3PG7 A;  1P3R A;  1DBH A;  2LYD A;  1XKE A;  1X1F A;  4A5K A;  2R09 A;  1BTN A;  3WA0 A;  2LOX A;  3OAN A;  1PMS A;  3WYF B;  2UZR A;  3X23 A;  1UPR A;  4CYE A;  1MK9 B;  1V89 A;  2J59 M;  1X11 A;  5L81 A;  1XD4 A;  4TKN A;  2ADZ A;  2Z0Q A;  2BCJ A;  4K2O A;  2COF A;  2NZ8 B;  2LG1 A;  2DHJ A;  1XX0 A;  2DA0 A;  5J3Q A;  5D3V A;  2GJY A;  2V76 A;  3GYP A;  1GC6 A;  1J0W A;  1DDW A;  3D8D A;  4YON A;  4GN1 A;  1I2H A;  4NSW A;  4GPT B;  1K5D B;  1H10 A;  2YSZ A; 
#chains in the Genus database with same CATH topology
 3SO6 A;  5C5B A;  4HDQ A;  5KCV A;  5D3W A;  3GYO A;  3DXD A;  1MAI A;  3V5W A;  4DX8 A;  5JP4 A;  2Z0P A;  3MDB C;  1I7A A;  4CHJ A;  1WG7 A;  1K5G B;  2P0H A;  2R2Y A;  4DBB A;  4C0A A;  3SNH A;  2ELA A;  1MPH A;  1UPQ A;  3A58 A;  5HE2 A;  4A6K A;  1U5E A;  2DTC A;  2H7D A;  3A8Q A;  3ZVR A;  2DX5 A;  2DYN A;  4HAX B;  2AEH A;  1MI1 A;  3G9W A;  2I1J A;  5D27 A;  1KI1 B;  3PVU A;  5JHG A;  4EJN A;  3HIE A;  4D6W A;  2OTX A;  5D3X A;  1WJ1 A;  1KZG A;  3P6A A;  4GXB A;  2Z14 A;  2COA A;  2UZS A;  1NU2 A;  1MIZ B;  2KUP A;  1W1G A;  1UNR A;  4K2P A;  3KSY A;  3SV1 A;  2YS5 A;  2H7E A;  4HHV A;  1V5P A;  1B55 A;  1ZYI A;  2AL6 A;  2ZPY A;  1M7E A;  1TQZ A;  3F5R A;  1WGQ A;  2RGN B;  1FGZ A;  3ODX A;  2W2X D;  1GG3 A;  4HAU B;  4GNK B;  2P0D A;  1ZM0 A;  1ZVR A;  2P8V A;  4CHM A;  2D11 A;  4KHO A;  3TO1 A;  2ELB A;  3PP2 A;  1TXD A;  1PLS A;  1UNQ A;  4HSI A;  2L2I A;  4CSQ A;  1X86 A;  2UVM A;  4BBK A;  1WI1 A;  1MK7 B;  1FOE A;  1NI2 A;  2VRW B;  4A6F B;  2COD A;  4HDO A;  3RCP A;  2K00 A;  2KR0 A;  3ULB A;  3B77 A;  3VOQ A;  4D0N B;  2J0M A;  3FM8 C;  3NW8 A;  3DXE A;  1P6S A;  2YT2 A;  3T06 A;  4KVG B;  2GCL A;  1UNP A;  1V61 A;  3ML4 A;  2M14 A;  2LUL A;  4ZRI A;  2W2X C;  1H4R A;  4HB0 B;  4Z2M B;  1FHW A;  1FHX A;  4OT1 A;  2D9Y A;  5JLJ B;  5JHH A;  2Y8F A;  2K2U A;  4Z2N A;  5FI0 A;  4H8S A;  4KHB A;  2R0D A;  2DHK A;  4MK0 A;  2LOZ A;  1SGH A;  1V5M A;  2RSG A;  1PFJ A;  1LW3 A;  2CRF A;  2RVB B;  2OQB A;  1XCG A;  5FI1 A;  3QWM A;  4B6H A;  5LG4 B;  2D9V A;  1N3H A;  2EJ8 A;  2DHI A;  2RUK B;  2CY4 A;  3HQC A;  4HB2 B;  2YF0 A;  1WVH A;  4HAY B;  2P0F A;  4QJ3 B;  3AU4 A;  1X05 A;  3DCX A;  3ODW A;  2I1K A;  5CLQ B;  2HE7 A;  1XR0 B;  5D3Y A;  1LB1 A;  4GZU A;  3BJI A;  5M4Y B;  3HSA A;  4WVF B;  5C6R A;  3PVW A;  2HTH B;  2Q13 A;  1AWE A;  4TYZ A;  3KY9 A;  2I5F A;  5DHF B;  4F7H A;  3DXC A;  5HE1 A;  2XQN M;  3D8E A;  2N0Y A;  2GUM A;  3LJU X;  3D8F A;  4ZRK A;  3CIK A;  5I2M A;  2EC1 A;  4EKU A;  1W1D A;  1U5G A;  5EFX A;  1QC6 A;  4YL8 A;  5GOW B;  3U7D A;  2L1C A;  3U8Z A;  2Z4D A;  3TFM A;  2I5C A;  2MFQ A;  4KHB B;  2IYB A;  2E2X A;  5HE0 A;  2LKO A;  4ZRJ A;  5C5B B;  4XWX A;  4QJ4 B;  2KIE A;  4IOY X;  1E5W A;  1U5D A;  1TJ6 A;  3A98 B;  4KHA A;  4F7U P;  4HB3 B;  1MKE A;  1FHO A;  3OHM B;  4K81 A;  2GCJ A;  2MDX A;  2EMT A;  2YT0 A;  4IAP A;  2YS1 A;  2GS0 A;  2DLW A;  3PEG A;  2EMS A;  2JP2 A;  1DDV A;  3QIJ A;  4A6H A;  1Z87 A;  5LON B;  2J0J A;  4GMV A;  1WJM A;  2CAY A;  4F7G A;  5LOP B;  2ROV A;  4K17 A;  2D9X A;  2DN6 A;  3NWD A;  2W2W A;  4KAX B;  2RRF A;  2K8E A;  2YVC A;  4DXA B;  4L6E A;  4MY6 A;  1WGU A;  3ULC A;  3IVF A;  3VIA A;  1RJ2 A;  2D9Z A;  4GOU A;  2IFS A;  1Q67 A;  3N7C A;  3NSU A;  2DFK A;  1NTY A;  3FVC A;  2DYQ A;  2MWN B;  5HE3 A;  2KGX B;  2J0K A;  4WJ7 A;  1P5T A;  1M7R A;  1FGY A;  2YRY A;  1QQG A;  3FEH A;  2Z13 A;  3SYX A;  1RRP B;  3O96 A;  1ZC3 B;  5DHA B;  1W1H A;  3TW1 A;  2VKI A;  1ISN A;  2Y7B A;  4PQ0 A;  3F0W A;  2D9W A;  4HAV B;  2M38 A;  1EF1 A;  1U29 A;  4HAT B;  5CLL B;  1GC7 A;  1MIX A;  2NBV A;  4MT7 A;  1X1G A;  5DH9 B;  3AU5 A;  2DX1 A;  4GMX B;  3A8P A;  2MKR A;  1FB8 A;  3ODO A;  2NMB A;  2FJL A;  2RNR B;  1FAO A;  1U5F A;  2KCJ A;  2Z0O A;  1BAK A;  4L1R A;  2COC A;  1EAZ A;  5KQ1 A;  2ZKM X;  4HB4 B;  4OSN A;  5C79 A;  2G35 A;  1DDM A;  1AQC A;  2KUQ A;  3QBV B;  1SHC A;  1V88 A;  3M1I B;  4HAW B;  2KIG A;  3BIN A;  1IRS A;  1DRO A;  3HW2 B;  1BWN A;  3NWF A;  2QKL A;  1U27 A;  3ZDT A;  3KZ1 A;  3PSC A;  2CY5 A;  4A6F A;  3KRW A;  1EGX A;  1ZC4 B;  1ZSQ A;  5KQ4 A;  2FJU B;  2D4Q A;  1EVH A;  1OMW A;  4Y94 A;  2PZ1 A;  2DKQ A;  2QKM A;  3HK0 A;  1KZ7 A;  4QXA B;  1Y19 B;  4PNK A;  2Y8G A;  3SUZ A;  4DX9 0;  2YT1 A;  5DIF B;  1U2B A;  4IFS A;  3NWA A;  1OQN A;  1UEF A;  1V5U A;  4HAZ B;  4NY0 A;  2ROZ B;  3TCA A;  1OY2 A;  1BTK A;  1DYN A;  2D2Q A;  1Y5O A;  3FSS A;  4QJ5 B;  2K2J A;  4WSF A;  1J19 A;  3PZD A;  5J3Y A;  2D10 A;  3CXB B;  3MPX A;  4P7I A;  3UZT A;  3TVV A;  2N23 A;  4EMO A;  2DKP A;  2X18 A;  3KRX A;  5J3T A;  2K49 A;  5C16 A;  3P7Z A;  2VSZ A;  3AJ4 A;  2RLO A;  2YS3 A;  1NTV A;  5DI9 B;  1XOD A;  3PG7 A;  3PVL A;  1P3R A;  1DBH A;  1T77 A;  2LYD A;  1XKE A;  1X1F A;  4A5K A;  5I2S A;  2R09 A;  1BTN A;  3WA0 A;  3U12 A;  2LOX A;  3OAN A;  1PMS A;  3WYF B;  2UZR A;  3X23 A;  1UPR A;  4CYE A;  1MK9 B;  1V89 A;  2J59 M;  5IRS A;  1X11 A;  5L81 A;  1XD4 A;  4TKN A;  2ADZ A;  2Z0Q A;  2BCJ A;  4K2O A;  2COF A;  2NZ8 B;  2LG1 A;  2DHJ A;  1XX0 A;  2DA0 A;  5J3Q A;  5D3V A;  2GJY A;  2V76 A;  3GYP A;  1GC6 A;  1J0W A;  1DDW A;  3D8D A;  4YON A;  2Z59 A;  4GN1 A;  1I2H A;  4NSW A;  4GPT B;  4DIX A;  1K5D B;  1H10 A;  2YSZ A; 
#chains in the Genus database with same CATH homology
 3SO6 A;  5C5B A;  4HDQ A;  5KCV A;  5D3W A;  3GYO A;  3DXD A;  1MAI A;  3V5W A;  4DX8 A;  5JP4 A;  2Z0P A;  3MDB C;  1I7A A;  4CHJ A;  1WG7 A;  1K5G B;  2P0H A;  4DBB A;  4C0A A;  3SNH A;  2ELA A;  1MPH A;  1UPQ A;  5HE2 A;  4A6K A;  1U5E A;  2DTC A;  2H7D A;  3A8Q A;  3ZVR A;  2DX5 A;  2DYN A;  4HAX B;  2AEH A;  3G9W A;  2I1J A;  5D27 A;  1KI1 B;  3PVU A;  5JHG A;  4EJN A;  2OTX A;  5D3X A;  1WJ1 A;  1KZG A;  3P6A A;  4GXB A;  2COA A;  2UZS A;  1NU2 A;  1MIZ B;  2KUP A;  1W1G A;  1UNR A;  4K2P A;  3KSY A;  3SV1 A;  2YS5 A;  2H7E A;  4HHV A;  1V5P A;  1B55 A;  2AL6 A;  2ZPY A;  1M7E A;  1TQZ A;  3F5R A;  1WGQ A;  2RGN B;  1FGZ A;  3ODX A;  2W2X D;  1GG3 A;  4HAU B;  2P0D A;  1ZM0 A;  1ZVR A;  2P8V A;  4CHM A;  2D11 A;  4KHO A;  3TO1 A;  2ELB A;  3PP2 A;  1TXD A;  1PLS A;  1UNQ A;  2L2I A;  1X86 A;  2UVM A;  4BBK A;  1WI1 A;  1MK7 B;  1FOE A;  1NI2 A;  2VRW B;  4A6F B;  2COD A;  4HDO A;  3RCP A;  2K00 A;  3ULB A;  3VOQ A;  4D0N B;  2J0M A;  3FM8 C;  3DXE A;  1P6S A;  3T06 A;  4KVG B;  2GCL A;  1UNP A;  1V61 A;  3ML4 A;  2M14 A;  2LUL A;  4ZRI A;  2W2X C;  1H4R A;  4HB0 B;  4Z2M B;  1FHW A;  1FHX A;  2D9Y A;  5JLJ B;  5JHH A;  2Y8F A;  2K2U A;  4Z2N A;  5FI0 A;  4H8S A;  2R0D A;  2DHK A;  4MK0 A;  2LOZ A;  1SGH A;  1V5M A;  2RSG A;  1PFJ A;  1LW3 A;  2CRF A;  2RVB B;  2OQB A;  1XCG A;  5FI1 A;  3QWM A;  4B6H A;  2D9V A;  1N3H A;  2EJ8 A;  2DHI A;  2RUK B;  2CY4 A;  3HQC A;  4HB2 B;  2YF0 A;  1WVH A;  4HAY B;  2P0F A;  3AU4 A;  1X05 A;  3ODW A;  2I1K A;  5CLQ B;  2HE7 A;  1XR0 B;  5D3Y A;  1LB1 A;  4GZU A;  3BJI A;  4WVF B;  5C6R A;  3PVW A;  2HTH B;  2Q13 A;  1AWE A;  4TYZ A;  3KY9 A;  2I5F A;  5DHF B;  4F7H A;  3DXC A;  5HE1 A;  2XQN M;  3D8E A;  2N0Y A;  3LJU X;  3D8F A;  4ZRK A;  3CIK A;  2EC1 A;  4EKU A;  1W1D A;  1U5G A;  5EFX A;  1QC6 A;  4YL8 A;  5GOW B;  3U7D A;  2L1C A;  3U8Z A;  3TFM A;  2I5C A;  2MFQ A;  4KHB B;  2IYB A;  2E2X A;  5HE0 A;  2LKO A;  4ZRJ A;  5C5B B;  4XWX A;  4IOY X;  1E5W A;  1U5D A;  1TJ6 A;  3A98 B;  4KHA A;  4F7U P;  4HB3 B;  1MKE A;  1FHO A;  4K81 A;  2GCJ A;  2MDX A;  2EMT A;  2YT0 A;  4IAP A;  2YS1 A;  2GS0 A;  2DLW A;  3PEG A;  2EMS A;  2JP2 A;  1DDV A;  3QIJ A;  4A6H A;  1Z87 A;  5LON B;  2J0J A;  4GMV A;  1WJM A;  2CAY A;  4F7G A;  5LOP B;  2ROV A;  4K17 A;  2D9X A;  2DN6 A;  2W2W A;  4KAX B;  2YVC A;  4DXA B;  4L6E A;  4MY6 A;  1WGU A;  3ULC A;  3IVF A;  3VIA A;  1RJ2 A;  2D9Z A;  2IFS A;  1Q67 A;  3N7C A;  3NSU A;  2DFK A;  1NTY A;  2DYQ A;  2MWN B;  5HE3 A;  2KGX B;  2J0K A;  4WJ7 A;  1P5T A;  1M7R A;  1FGY A;  2YRY A;  1QQG A;  3FEH A;  3SYX A;  1RRP B;  3O96 A;  1ZC3 B;  5DHA B;  1W1H A;  3TW1 A;  2VKI A;  1ISN A;  2Y7B A;  4PQ0 A;  3F0W A;  2D9W A;  4HAV B;  2M38 A;  1EF1 A;  1U29 A;  4HAT B;  5CLL B;  1GC7 A;  1MIX A;  4MT7 A;  1X1G A;  5DH9 B;  3AU5 A;  2DX1 A;  4GMX B;  3A8P A;  2MKR A;  1FB8 A;  3ODO A;  2NMB A;  2FJL A;  2RNR B;  1FAO A;  1U5F A;  2KCJ A;  2Z0O A;  1BAK A;  2COC A;  1EAZ A;  5KQ1 A;  4HB4 B;  5C79 A;  2G35 A;  1DDM A;  1AQC A;  3QBV B;  1SHC A;  1V88 A;  3M1I B;  4HAW B;  3BIN A;  1IRS A;  1DRO A;  3HW2 B;  1BWN A;  2QKL A;  1U27 A;  3ZDT A;  3KZ1 A;  3PSC A;  2CY5 A;  4A6F A;  3KRW A;  1EGX A;  1ZC4 B;  1ZSQ A;  5KQ4 A;  2D4Q A;  1EVH A;  1OMW A;  4Y94 A;  2PZ1 A;  2DKQ A;  2QKM A;  3HK0 A;  1KZ7 A;  1Y19 B;  4PNK A;  2Y8G A;  3SUZ A;  4DX9 0;  2YT1 A;  5DIF B;  1U2B A;  4IFS A;  1OQN A;  1UEF A;  1V5U A;  4HAZ B;  4NY0 A;  2ROZ B;  3TCA A;  1OY2 A;  1BTK A;  1DYN A;  2D2Q A;  1Y5O A;  3FSS A;  2K2J A;  4WSF A;  1J19 A;  3PZD A;  5J3Y A;  2D10 A;  3CXB B;  3MPX A;  4P7I A;  3UZT A;  3TVV A;  2N23 A;  4EMO A;  2DKP A;  2X18 A;  3KRX A;  5J3T A;  5C16 A;  3P7Z A;  2VSZ A;  3AJ4 A;  2RLO A;  2YS3 A;  1NTV A;  5DI9 B;  1XOD A;  3PVL A;  3PG7 A;  1P3R A;  1DBH A;  2LYD A;  1XKE A;  1X1F A;  4A5K A;  2R09 A;  1BTN A;  3WA0 A;  2LOX A;  3OAN A;  1PMS A;  3WYF B;  2UZR A;  3X23 A;  1UPR A;  4CYE A;  1MK9 B;  1V89 A;  2J59 M;  1X11 A;  5L81 A;  1XD4 A;  4TKN A;  2ADZ A;  2Z0Q A;  2BCJ A;  4K2O A;  2COF A;  2NZ8 B;  2LG1 A;  2DHJ A;  1XX0 A;  2DA0 A;  5J3Q A;  5D3V A;  2GJY A;  2V76 A;  3GYP A;  1GC6 A;  1J0W A;  1DDW A;  3D8D A;  4YON A;  4GN1 A;  1I2H A;  4NSW A;  4GPT B;  1K5D B;  1H10 A;  2YSZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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