2V4BA

Crystal structure of human adamts-1 catalytic domain and cysteine- rich domain (apo-form)
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
296
structure length
280
Chain Sequence
SHRYVETMLVADQSMAEFHGSGLKHYLLTLFSVAARLYKHPSIRNSVSLVVVKILVIHDEQKGPEVTSNAALTLRNFCNWQKQHNPPSDRDAEHYDTAILFTRQDLCGSQTCDTLGMADVGTVCDPSRSCSVIEDDGLQAAFTTAHELGHVFNMPHDDAKQCASLNSHMMASMLDHSQPWSPCSAYMITSFLDNGHGECLMDKPQNPIQLPGDLPGTSYDANRQCQFTFGEDSKHCPTCSTLWCTGVLVCQTKHFPWADGTSCGEGKWCINGKCVNKLVP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of Human Adamts-1 Reveal a Conserved Catalytic Domain and a Disintegrin-Like Domain with a Fold Homologous to Cysteine-Rich Domains.
pubmed doi rcsb
molecule keywords ADAMTS-1
molecule tags Hydrolase
source organism Homo sapiens
total genus 93
structure length 280
sequence length 296
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2007-06-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01421 Reprolysin Reprolysin (M12B) family zinc metalloprotease
A PF17771 ADAM_CR_2 ADAM cysteine-rich domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2v4bA01
2OXWA 3B2ZA 1AF0A 4XM6A 5B5OA 3RTSA 1HTDA 3LJTA 1C3IA 4JIJA 1BZSA 4PKTA 2OY2A 2CLTA 5BOTA 2N8RA 4ON1A 4CTHA 2X7MA 3LJGA 1JAOA 4JA1A 1BIWA 3F16A 2JSDA 5I4OA 3HBUP 2PJTA 1C7KA 2D1OA 3SHIA 1CGFA 1RM8A 1KUIA 1KUFA 3KMEA 1KUHA 5I3MA 1D8FA 1SMPA 3EHXA 1C8TA 3KMCA 3LJZA 1SATA 2OW0A 5H8XA 5B5PA 3OHLA 1ZTQA 3NX7A 4L6TA 3ELMA 1WNIA 4DV8A 1PWWA 4WKIA 966CA 3HDAP 4DD8A 2X3CA 3ZXHA 5D1SA 5CXAA 2W0DA 1G9KA 1OS9A 1JAPA 3KEJA 2ERPA 3HY9A 2DW0A 1BKCE 1K7IA 3G5CA 1ZS0A 3F19A 3HBVP 1XUCA 3F18A 3U1RA 3AYKA 1R1HA 3P24A 3EWJA 2MLRA 1CGEA 1GXDA 1XFXA 2E3XA 1JANA 1GKCA 3LMCA 1OS2A 1EB6A 4PKVA 3HB2P 2OXUA 1ZXCA 1R54A 1DMTA 1XUDA 1BQQM 5D1TA 4A7BA 1FM1A 5L7FA 2RJQA 2J83A 3EDGA 1FLSA 1AYKA 1PWPA 1OM6A 1QICA 1XFVA 2OW1A 2E2DA 2OZRA 3MA2A 4JQGA 2OXZA 2FV9A 3LUNA 4WK7A 3LGPA 1KAPP 1JIZA 1ZVXA 4GWMA 1OM7A 4G0DA 1EUBA 1Y0VA 4GUYA 4DF9A 4EFSA 1GO7P 1BSWA 3I7GA 830CA 2JT6A 1MMQA 1CGLA 4H82A 4ZR5A 4AXQA 1JH1A 2ERQA 4AUOA 3CKIA 3N2UA 1R55A 2YB9A 1UMTA 3RTTA 1UEAA 1BUDA 1MMBA 5CUHA 3LQBA 2J0TA 1IACA 2WO8A 3Q2GA 4JPAA 1H71P 4XM7A 5I0LA 2EROA 2O36A 1S4BP 1FBLA 4IJOA 1HOVA 1R1IA 3DWBA 3EDZA 5BOYA 1XFZA 1USNA 2FV5A 3LILA 1HY7A 2Y6CA 1IABA 4PKQA 1I1IP 2OY4A 3KRYA 4FXQA 2KRJA 5CZMA 4IN9A 2CKIA 3N2VA 1B8YA 3K7NA 3ZVSA 2X3AA 4DPEA 2OVZA 3LKAA 2MZIA 3DSLA 1CK7A 3AYUA 4Q1LA 1AKLA 2DW2A 3HDBA 1MMRA 4ILWD 3E8RA 1G12A 4GR8A 1BKCI 3KHIA 1SLNA 1IAEA 1G05A 1PWVA 1RMZA 2USNA 1CAQA 3L0VA 2TCLA 4PKRA 2OVXA 1G49A 3B92A 3DPFA 5L79A 1J7NA 1BQOA 1I73A 1XFYA 1ASTA 2W12A 3F15A 1KUKA 1YCMA 3TVCA 1CQRA 4GQLA 2W14A 2OW2A 3LIRA 1PWUA 3ZUKA 3TS4A 1GE6A 1D8MA 1QIBA 1XURA 3KEKA 2AYKA 4FVLA 1O0TA 1ND1A 5LABA 4IUWA 1I76A 1QIAA 4I35A 1SRPA 5D2BA 456CA 5JMYA 2AIGP 3HYGA 2QPJA 4WZVA 2JIHA 2JT5A 3OHOA 2XS4A 1HFSA 4WKEA 1SLMA 1HV5A 1JAQA 3O2XA 3VI1A 1Y93A 3WV3A 2RJPA 1K7GA 4XCTA 1A85A 3EDHA 3P1VA 3DPEA 3LK8A 1JKYA 4HMAA 1OMJA 1UTZA 1SU3A 2WO9A 4H49A 5I43A 1YQYA 4PKWA 2SRTA 4QKZA 1QUAA 3KWVC 3TSKA 4L63A 2OI0A 3TT4A 1IAAA 3LE9A 4XBHA 1BM6A 3L0TA 1K7QA 1UMSA 1IAGA 1XFWA 1A86A 3LIKA 2JNPA 1ROSA 1Z3JA 4GR3A 4GWNA 2K9CA 4H30A 2POJA 1OO9A 4AIGA 1ZXVA 4JP4A 4A3WA 4H84A 3UVCA 1O0QA 2MZEA 3I7IA 3K7LA 2I47A 4H2EA 4GF1A 4WF6A 1IADA 1EAKA 2WOAA 1JK3A 3EHYA 2W13A 3F1AA 3LQ0A 2Z2DA 1GE5A 4XM8A 3WV1A 3WV2A 1BUVM 3KECA 1OM8A 5D1UA 3USNA 1PWQA 1QJJA 1KUGA 4FU4A 3O64A 1D7XA 3G42A 4J4MA 1GE7A 1Q3AA 2A8HA 1QJIA 2D1NA 1MMPA 3EDIA 5I2ZA 3V96B 1UTTA 1XFUA 1BKCA 2K2GA 5D7WA 4L19A 1CIZA 3Q2HA 1JJ9A 3BA0A 3HY7A 2XS3A 1L6JA 4H3XA 1JIWP 4AYKA 4PKUA 1DTHA 1GKDA 4R3VA 1ATLA 4GR0A 1KBCA 4I03A 1YP1A 2DW1A 2OW9A 1R1JA 2DDFA 2DDYA 1ZP5A 5I12A 2MLSA 4G9LA 2L0RA 2O3EA 3LEAA 2W15A 3AIGA 4FXYP 5D3CA 2YIGA 3B8ZA 2Y6DA 1Y8JA 1HFCA 1MNCA 3LUMA 2MZHA 1GO8P 2V4BA 4PKSA 3VTGA 4H76A 4H1QA 1D5JA 3DL1A 3GBOA 3F17A 1B3DA 2HU6A 1CXVA 1YOUA 2X3BA 3DNGA 5BPAA 4HX3A 1G4KA
chains in the Genus database with same CATH superfamily
2OXWA 3B2ZA 1AF0A 4XM6A 5B5OA 3RTSA 1HTDA 3LJTA 1C3IA 4JIJA 3DTEA 1BZSA 4PKTA 2OY2A 2CLTA 5BOTA 2N8RA 4ON1A 4CTHA 2X7MA 1XM5A 3LJGA 1JAOA 4JA1A 1BIWA 3F16A 2JSDA 5I4OA 3HBUP 2PJTA 1C7KA 2D1OA 3SHIA 1CGFA 1RM8A 1KUIA 1KUFA 3KMEA 1KUHA 5I3MA 1D8FA 1SMPA 3EHXA 1C8TA 3KMCA 3LJZA 1SATA 2OW0A 5H8XA 5B5PA 3OHLA 1ZTQA 3NX7A 4L6TA 3ELMA 1WNIA 4DV8A 1PWWA 4WKIA 966CA 3HDAP 4DD8A 2X3CA 3ZXHA 5D1SA 5CXAA 2W0DA 1G9KA 1OS9A 1JAPA 3KEJA 2ERPA 3HY9A 2DW0A 1BKCE 1K7IA 3G5CA 1ZS0A 3F19A 3HBVP 1XUCA 3F18A 3U1RA 3AYKA 1R1HA 3P24A 3EWJA 2MLRA 1CGEA 1GXDA 1XFXA 2E3XA 1JANA 1GKCA 3LMCA 1OS2A 1EB6A 1XAXA 4PKVA 3HB2P 2OXUA 1ZXCA 4L7AA 1R54A 1DMTA 1XUDA 1BQQM 5D1TA 4A7BA 1FM1A 5L7FA 2RJQA 2J83A 3EDGA 1FLSA 1AYKA 1PWPA 1OM6A 1QICA 1XFVA 2OW1A 2E2DA 2OZRA 3MA2A 4JQGA 2OXZA 2FV9A 3LUNA 4WK7A 3LGPA 1KAPP 1JIZA 1ZVXA 4GWMA 1OM7A 4G0DA 1EUBA 1Y0VA 4GUYA 4DF9A 4EFSA 1GO7P 1BSWA 3I7GA 830CA 2JT6A 1MMQA 1CGLA 4H82A 4ZR5A 4AXQA 1JH1A 2ERQA 4AUOA 3CKIA 3N2UA 1R55A 2YB9A 1UMTA 3RTTA 1UEAA 1BUDA 1MMBA 5CUHA 3LQBA 2J0TA 1IACA 2WO8A 3Q2GA 4JPAA 1H71P 4XM7A 5I0LA 2EROA 2O36A 1S4BP 1FBLA 4IJOA 1HOVA 1R1IA 3DWBA 3EDZA 5BOYA 1XFZA 1USNA 2FV5A 3LILA 1HY7A 2Y6CA 1IABA 4PKQA 1I1IP 2OY4A 3KRYA 4FXQA 2KRJA 5CZMA 4IN9A 2CKIA 3N2VA 1B8YA 3K7NA 3ZVSA 2X3AA 4DPEA 2OVZA 3LKAA 2MZIA 3DSLA 1CK7A 3AYUA 4Q1LA 1AKLA 2DW2A 3HDBA 1MMRA 4ILWD 3E8RA 1G12A 4GR8A 1BKCI 3KHIA 1SLNA 1IAEA 1G05A 1PWVA 1RMZA 2USNA 1CAQA 3L0VA 2TCLA 4PKRA 2OVXA 1G49A 3B92A 3DPFA 5L79A 1J7NA 1BQOA 1I73A 1XFYA 1ASTA 2W12A 3F15A 1KUKA 1YCMA 3TVCA 1CQRA 4GQLA 2W14A 2OW2A 3LIRA 1PWUA 3ZUKA 3DTKA 3TS4A 3DTIA 1GE6A 1D8MA 1QIBA 1XURA 3KEKA 2AYKA 4FVLA 1O0TA 1ND1A 5LABA 4IUWA 1I76A 1QIAA 4I35A 1SRPA 5D2BA 456CA 5JMYA 2AIGP 3HYGA 2QPJA 4WZVA 2JIHA 2JT5A 3OHOA 2XS4A 1HFSA 4WKEA 1SLMA 1HV5A 1OZ9A 1JAQA 3O2XA 3VI1A 1Y93A 3WV3A 2RJPA 1K7GA 4XCTA 1A85A 2YUFA 3EDHA 3P1VA 3DPEA 3LK8A 1JKYA 4HMAA 1OMJA 1UTZA 1SU3A 2WO9A 4H49A 5I43A 1YQYA 4PKWA 2SRTA 4QKZA 1QUAA 3KWVC 3TSKA 4L63A 2OI0A 3TT4A 1IAAA 3LE9A 4XBHA 1BM6A 3L0TA 1K7QA 1UMSA 1IAGA 1XFWA 1A86A 3LIKA 2JNPA 1ROSA 1Z3JA 4GR3A 4GWNA 2K9CA 1TVIA 2POJA 4H30A 1OO9A 4AIGA 1ZXVA 4JP4A 4A3WA 4H84A 3UVCA 1O0QA 2MZEA 3I7IA 3K7LA 2I47A 4H2EA 4GF1A 4WF6A 1IADA 1EAKA 2WOAA 1JK3A 3EHYA 2W13A 3F1AA 3LQ0A 2Z2DA 1GE5A 4XM8A 3WV1A 3WV2A 1BUVM 3KECA 1OM8A 5D1UA 3USNA 1PWQA 1QJJA 1KUGA 4FU4A 3O64A 1D7XA 3G42A 4J4MA 1GE7A 1Q3AA 2A8HA 1QJIA 2D1NA 1MMPA 3EDIA 5I2ZA 3V96B 1UTTA 1XFUA 1BKCA 2K2GA 5D7WA 4L19A 1CIZA 3Q2HA 1JJ9A 3BA0A 3HY7A 2XS3A 1L6JA 4H3XA 1JIWP 4AYKA 4PKUA 1DTHA 1GKDA 4R3VA 1ATLA 4GR0A 1KBCA 4I03A 1YP1A 2DW1A 2OW9A 1R1JA 2DDFA 2DDYA 1ZP5A 5I12A 2MLSA 4G9LA 2L0RA 2O3EA 3LEAA 2W15A 3AIGA 4FXYP 5D3CA 2YIGA 3B8ZA 2Y6DA 1Y8JA 1HFCA 1MNCA 3LUMA 2MZHA 1GO8P 2V4BA 4PKSA 3VTGA 4H76A 4H1QA 1D5JA 3DL1A 3GBOA 3F17A 1B3DA 2HU6A 1CXVA 1YOUA 2X3BA 3DNGA 5BPAA 4HX3A 1G4KA
chains in the Genus database with same CATH topology
2OXWA 3B2ZA 1AF0A 4XM6A 5B5OA 3RTSA 1HTDA 3LJTA 1C3IA 4JIJA 3DTEA 1BZSA 4PKTA 2OY2A 2CLTA 5BOTA 2N8RA 4ON1A 4CTHA 2X7MA 3LJGA 1JAOA 4JA1A 1BIWA 3F16A 2JSDA 5I4OA 3HBUP 2PJTA 1C7KA 2D1OA 3SHIA 1CGFA 1RM8A 1KUIA 1KUFA 3KMEA 1KUHA 5I3MA 1D8FA 1SMPA 3EHXA 1C8TA 3KMCA 3LJZA 1SATA 2OW0A 5H8XA 5B5PA 3OHLA 1ZTQA 3NX7A 4L6TA 3ELMA 1WNIA 4DV8A 1PWWA 4WKIA 966CA 3HDAP 4DD8A 2X3CA 3ZXHA 5D1SA 5CXAA 2W0DA 1G9KA 1OS9A 1JAPA 3KEJA 2ERPA 3HY9A 2DW0A 1BKCE 1K7IA 3G5CA 1ZS0A 3F19A 3HBVP 1XUCA 3F18A 3U1RA 3AYKA 1R1HA 3P24A 3EWJA 2MLRA 1CGEA 1GXDA 1XFXA 2E3XA 1JANA 1GKCA 3LMCA 1OS2A 1EB6A 4PKVA 3HB2P 2OXUA 1ZXCA 4L7AA 1R54A 1DMTA 1XUDA 1BQQM 5D1TA 4A7BA 1FM1A 5L7FA 2RJQA 2J83A 3EDGA 1FLSA 1AYKA 1PWPA 1OM6A 1QICA 1XFVA 2OW1A 2E2DA 2OZRA 3MA2A 4JQGA 2OXZA 2FV9A 3LUNA 4WK7A 3LGPA 1KAPP 1JIZA 1ZVXA 4GWMA 1OM7A 4G0DA 1EUBA 1Y0VA 4GUYA 4DF9A 4EFSA 1GO7P 1BSWA 3I7GA 830CA 2JT6A 1MMQA 1CGLA 4H82A 4ZR5A 4AXQA 1JH1A 2ERQA 4AUOA 3CKIA 3N2UA 1R55A 2YB9A 1UMTA 3RTTA 1UEAA 1BUDA 1MMBA 5CUHA 3LQBA 2J0TA 1IACA 2WO8A 3Q2GA 4JPAA 1H71P 4XM7A 5I0LA 2EROA 2O36A 1S4BP 1FBLA 4IJOA 1HOVA 1R1IA 3DWBA 3EDZA 5BOYA 1XFZA 1USNA 2FV5A 3LILA 1HY7A 2Y6CA 1IABA 4PKQA 1I1IP 2OY4A 3KRYA 4FXQA 2KRJA 5CZMA 4IN9A 2CKIA 3N2VA 1B8YA 3K7NA 3ZVSA 2X3AA 4DPEA 2OVZA 3LKAA 2MZIA 3DSLA 1CK7A 3AYUA 4Q1LA 1AKLA 2DW2A 3HDBA 1MMRA 4ILWD 3E8RA 1G12A 4GR8A 1BKCI 3KHIA 1SLNA 1IAEA 1G05A 1PWVA 1RMZA 2USNA 1CAQA 3L0VA 2TCLA 4PKRA 2OVXA 1G49A 3B92A 3DPFA 5L79A 1J7NA 1BQOA 1I73A 1XFYA 1ASTA 2W12A 3F15A 1KUKA 1YCMA 3TVCA 1CQRA 4GQLA 2W14A 2OW2A 3LIRA 1PWUA 3ZUKA 3DTKA 3TS4A 3DTIA 1GE6A 1D8MA 1QIBA 1XURA 3KEKA 2AYKA 4FVLA 1O0TA 1ND1A 5LABA 4IUWA 1I76A 1QIAA 4I35A 1SRPA 5D2BA 456CA 5JMYA 2AIGP 3HYGA 2QPJA 4WZVA 2JIHA 2JT5A 3OHOA 2XS4A 1HFSA 4WKEA 1SLMA 1HV5A 1JAQA 3O2XA 3VI1A 1Y93A 3WV3A 2RJPA 1K7GA 4XCTA 1A85A 2YUFA 3EDHA 3P1VA 3DPEA 3LK8A 1JKYA 4HMAA 1OMJA 1UTZA 1SU3A 2WO9A 4H49A 5I43A 1YQYA 4PKWA 2SRTA 4QKZA 1QUAA 3KWVC 3TSKA 4L63A 2OI0A 3TT4A 1IAAA 3LE9A 4XBHA 1BM6A 3L0TA 1K7QA 1UMSA 1IAGA 1XFWA 1A86A 3LIKA 2JNPA 1ROSA 1Z3JA 4GR3A 4GWNA 2K9CA 4H30A 2POJA 1OO9A 4AIGA 1ZXVA 4JP4A 4A3WA 4H84A 3UVCA 1O0QA 2MZEA 3I7IA 3K7LA 2I47A 4H2EA 4GF1A 4WF6A 1IADA 1EAKA 2WOAA 1JK3A 3EHYA 2W13A 3F1AA 3LQ0A 2Z2DA 1GE5A 4XM8A 3WV1A 3WV2A 1BUVM 3KECA 1OM8A 5D1UA 3USNA 1PWQA 1QJJA 1KUGA 4FU4A 3O64A 1D7XA 3G42A 4J4MA 1GE7A 1Q3AA 2A8HA 1QJIA 2D1NA 1MMPA 3EDIA 5I2ZA 3V96B 1UTTA 1XFUA 1BKCA 2K2GA 5D7WA 4L19A 1CIZA 3Q2HA 1JJ9A 3BA0A 3HY7A 2XS3A 1L6JA 4H3XA 1JIWP 4AYKA 4PKUA 1DTHA 1GKDA 4R3VA 1ATLA 4GR0A 1KBCA 4I03A 1YP1A 2DW1A 2OW9A 1R1JA 2DDFA 2DDYA 1ZP5A 5I12A 2MLSA 4G9LA 2L0RA 2O3EA 3LEAA 2W15A 3AIGA 4FXYP 5D3CA 2YIGA 3B8ZA 2Y6DA 1Y8JA 1HFCA 1MNCA 3LUMA 2MZHA 1GO8P 2V4BA 4PKSA 3VTGA 4H76A 4H1QA 1D5JA 3DL1A 3GBOA 3F17A 1B3DA 2HU6A 1CXVA 1YOUA 2X3BA 3DNGA 5BPAA 4HX3A 1G4KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OXW A;  3B2Z A;  1AF0 A;  4XM6 A;  5B5O A;  3RTS A;  1HTD A;  3LJT A;  1C3I A;  4JIJ A;  1BZS A;  4PKT A;  2OY2 A;  2CLT A;  5BOT A;  2N8R A;  4ON1 A;  4CTH A;  2X7M A;  3LJG A;  1JAO A;  4JA1 A;  1BIW A;  3F16 A;  2JSD A;  5I4O A;  3HBU P;  2PJT A;  1C7K A;  2D1O A;  3SHI A;  1CGF A;  1RM8 A;  1KUI A;  1KUF A;  3KME A;  1KUH A;  5I3M A;  1D8F A;  1SMP A;  3EHX A;  1C8T A;  3KMC A;  3LJZ A;  1SAT A;  2OW0 A;  5H8X A;  5B5P A;  3OHL A;  1ZTQ A;  3NX7 A;  4L6T A;  3ELM A;  1WNI A;  4DV8 A;  1PWW A;  4WKI A;  966C A;  3HDA P;  4DD8 A;  2X3C A;  3ZXH A;  5D1S A;  5CXA A;  2W0D A;  1G9K A;  1OS9 A;  1JAP A;  3KEJ A;  2ERP A;  3HY9 A;  2DW0 A;  1BKC E;  1K7I A;  3G5C A;  1ZS0 A;  3F19 A;  3HBV P;  1XUC A;  3F18 A;  3U1R A;  3AYK A;  1R1H A;  3P24 A;  3EWJ A;  2MLR A;  1CGE A;  1GXD A;  1XFX A;  2E3X A;  1JAN A;  1GKC A;  3LMC A;  1OS2 A;  1EB6 A;  4PKV A;  3HB2 P;  2OXU A;  1ZXC A;  1R54 A;  1DMT A;  1XUD A;  1BQQ M;  5D1T A;  4A7B A;  1FM1 A;  5L7F A;  2RJQ A;  2J83 A;  3EDG A;  1FLS A;  1AYK A;  1PWP A;  1OM6 A;  1QIC A;  1XFV A;  2OW1 A;  2E2D A;  2OZR A;  3MA2 A;  4JQG A;  2OXZ A;  2FV9 A;  3LUN A;  4WK7 A;  3LGP A;  1KAP P;  1JIZ A;  1ZVX A;  4GWM A;  1OM7 A;  4G0D A;  1EUB A;  1Y0V A;  4GUY A;  4DF9 A;  4EFS A;  1GO7 P;  1BSW A;  3I7G A;  830C A;  2JT6 A;  1MMQ A;  1CGL A;  4H82 A;  4ZR5 A;  4AXQ A;  1JH1 A;  2ERQ A;  4AUO A;  3CKI A;  3N2U A;  1R55 A;  2YB9 A;  1UMT A;  3RTT A;  1UEA A;  1BUD A;  1MMB A;  5CUH A;  3LQB A;  2J0T A;  1IAC A;  2WO8 A;  3Q2G A;  4JPA A;  1H71 P;  4XM7 A;  5I0L A;  2ERO A;  2O36 A;  1S4B P;  1FBL A;  4IJO A;  1HOV A;  1R1I A;  3DWB A;  3EDZ A;  5BOY A;  1XFZ A;  1USN A;  2FV5 A;  3LIL A;  1HY7 A;  2Y6C A;  1IAB A;  4PKQ A;  1I1I P;  2OY4 A;  3KRY A;  4FXQ A;  2KRJ A;  5CZM A;  4IN9 A;  2CKI A;  3N2V A;  1B8Y A;  3K7N A;  3ZVS A;  2X3A A;  4DPE A;  2OVZ A;  3LKA A;  2MZI A;  3DSL A;  1CK7 A;  3AYU A;  4Q1L A;  1AKL A;  2DW2 A;  3HDB A;  1MMR A;  4ILW D;  3E8R A;  1G12 A;  4GR8 A;  1BKC I;  3KHI A;  1SLN A;  1IAE A;  1G05 A;  1PWV A;  1RMZ A;  2USN A;  1CAQ A;  3L0V A;  2TCL A;  4PKR A;  2OVX A;  1G49 A;  3B92 A;  3DPF A;  5L79 A;  1J7N A;  1BQO A;  1I73 A;  1XFY A;  1AST A;  2W12 A;  3F15 A;  1KUK A;  1YCM A;  3TVC A;  1CQR A;  4GQL A;  2W14 A;  2OW2 A;  3LIR A;  1PWU A;  3ZUK A;  3TS4 A;  1GE6 A;  1D8M A;  1QIB A;  1XUR A;  3KEK A;  2AYK A;  4FVL A;  1O0T A;  1ND1 A;  5LAB A;  4IUW A;  1I76 A;  1QIA A;  4I35 A;  1SRP A;  5D2B A;  456C A;  5JMY A;  2AIG P;  3HYG A;  2QPJ A;  4WZV A;  2JIH A;  2JT5 A;  3OHO A;  2XS4 A;  1HFS A;  4WKE A;  1SLM A;  1HV5 A;  1JAQ A;  3O2X A;  3VI1 A;  1Y93 A;  3WV3 A;  2RJP A;  1K7G A;  4XCT A;  1A85 A;  3EDH A;  3P1V A;  3DPE A;  3LK8 A;  1JKY A;  4HMA A;  1OMJ A;  1UTZ A;  1SU3 A;  2WO9 A;  4H49 A;  5I43 A;  1YQY A;  4PKW A;  2SRT A;  4QKZ A;  1QUA A;  3KWV C;  3TSK A;  4L63 A;  2OI0 A;  3TT4 A;  1IAA A;  3LE9 A;  4XBH A;  1BM6 A;  3L0T A;  1K7Q A;  1UMS A;  1IAG A;  1XFW A;  1A86 A;  3LIK A;  2JNP A;  1ROS A;  1Z3J A;  4GR3 A;  4GWN A;  2K9C A;  4H30 A;  2POJ A;  1OO9 A;  4AIG A;  1ZXV A;  4JP4 A;  4A3W A;  4H84 A;  3UVC A;  1O0Q A;  2MZE A;  3I7I A;  3K7L A;  2I47 A;  4H2E A;  4GF1 A;  4WF6 A;  1IAD A;  1EAK A;  2WOA A;  1JK3 A;  3EHY A;  2W13 A;  3F1A A;  3LQ0 A;  2Z2D A;  1GE5 A;  4XM8 A;  3WV1 A;  3WV2 A;  1BUV M;  3KEC A;  1OM8 A;  5D1U A;  3USN A;  1PWQ A;  1QJJ A;  1KUG A;  4FU4 A;  3O64 A;  1D7X A;  3G42 A;  4J4M A;  1GE7 A;  1Q3A A;  2A8H A;  1QJI A;  2D1N A;  1MMP A;  3EDI A;  5I2Z A;  3V96 B;  1UTT A;  1XFU A;  1BKC A;  2K2G A;  5D7W A;  4L19 A;  1CIZ A;  3Q2H A;  1JJ9 A;  3BA0 A;  3HY7 A;  2XS3 A;  1L6J A;  4H3X A;  1JIW P;  4AYK A;  4PKU A;  1DTH A;  1GKD A;  4R3V A;  1ATL A;  4GR0 A;  1KBC A;  4I03 A;  1YP1 A;  2DW1 A;  2OW9 A;  1R1J A;  2DDF A;  2DDY A;  1ZP5 A;  5I12 A;  2MLS A;  4G9L A;  2L0R A;  2O3E A;  3LEA A;  2W15 A;  3AIG A;  4FXY P;  5D3C A;  2YIG A;  3B8Z A;  2Y6D A;  1Y8J A;  1HFC A;  1MNC A;  3LUM A;  2MZH A;  1GO8 P;  2V4B A;  4PKS A;  3VTG A;  4H76 A;  4H1Q A;  1D5J A;  3DL1 A;  3GBO A;  3F17 A;  1B3D A;  2HU6 A;  1CXV A;  1YOU A;  2X3B A;  3DNG A;  5BPA A;  4HX3 A;  1G4K A; 
#chains in the Genus database with same CATH topology
 2OXW A;  3B2Z A;  1AF0 A;  4XM6 A;  5B5O A;  3RTS A;  1HTD A;  3LJT A;  1C3I A;  4JIJ A;  3DTE A;  1BZS A;  4PKT A;  2OY2 A;  2CLT A;  5BOT A;  2N8R A;  4ON1 A;  4CTH A;  2X7M A;  1XM5 A;  3LJG A;  1JAO A;  4JA1 A;  1BIW A;  3F16 A;  2JSD A;  5I4O A;  3HBU P;  2PJT A;  1C7K A;  2D1O A;  3SHI A;  1CGF A;  1RM8 A;  1KUI A;  1KUF A;  3KME A;  1KUH A;  5I3M A;  1D8F A;  1SMP A;  3EHX A;  1C8T A;  3KMC A;  3LJZ A;  1SAT A;  2OW0 A;  5H8X A;  5B5P A;  3OHL A;  1ZTQ A;  3NX7 A;  4L6T A;  3ELM A;  1WNI A;  4DV8 A;  1PWW A;  4WKI A;  966C A;  3HDA P;  4DD8 A;  2X3C A;  3ZXH A;  5D1S A;  5CXA A;  2W0D A;  1G9K A;  1OS9 A;  1JAP A;  3KEJ A;  2ERP A;  3HY9 A;  2DW0 A;  1BKC E;  1K7I A;  3G5C A;  1ZS0 A;  3F19 A;  3HBV P;  1XUC A;  3F18 A;  3U1R A;  3AYK A;  1R1H A;  3P24 A;  3EWJ A;  2MLR A;  1CGE A;  1GXD A;  1XFX A;  2E3X A;  1JAN A;  1GKC A;  3LMC A;  1OS2 A;  1EB6 A;  1XAX A;  4PKV A;  3HB2 P;  2OXU A;  1ZXC A;  4L7A A;  1R54 A;  1DMT A;  1XUD A;  1BQQ M;  5D1T A;  4A7B A;  1FM1 A;  5L7F A;  2RJQ A;  2J83 A;  3EDG A;  1FLS A;  1AYK A;  1PWP A;  1OM6 A;  1QIC A;  1XFV A;  2OW1 A;  2E2D A;  2OZR A;  3MA2 A;  4JQG A;  2OXZ A;  2FV9 A;  3LUN A;  4WK7 A;  3LGP A;  1KAP P;  1JIZ A;  1ZVX A;  4GWM A;  1OM7 A;  4G0D A;  1EUB A;  1Y0V A;  4GUY A;  4DF9 A;  4EFS A;  1GO7 P;  1BSW A;  3I7G A;  830C A;  2JT6 A;  1MMQ A;  1CGL A;  4H82 A;  4ZR5 A;  4AXQ A;  1JH1 A;  2ERQ A;  4AUO A;  3CKI A;  3N2U A;  1R55 A;  2YB9 A;  1UMT A;  3RTT A;  1UEA A;  1BUD A;  1MMB A;  5CUH A;  3LQB A;  2J0T A;  1IAC A;  2WO8 A;  3Q2G A;  4JPA A;  1H71 P;  4XM7 A;  5I0L A;  2ERO A;  2O36 A;  1S4B P;  1FBL A;  4IJO A;  1HOV A;  1R1I A;  3DWB A;  3EDZ A;  5BOY A;  1XFZ A;  1USN A;  2FV5 A;  3LIL A;  1HY7 A;  2Y6C A;  1IAB A;  4PKQ A;  1I1I P;  2OY4 A;  3KRY A;  4FXQ A;  2KRJ A;  5CZM A;  4IN9 A;  2CKI A;  3N2V A;  1B8Y A;  3K7N A;  3ZVS A;  2X3A A;  4DPE A;  2OVZ A;  3LKA A;  2MZI A;  3DSL A;  1CK7 A;  3AYU A;  4Q1L A;  1AKL A;  2DW2 A;  3HDB A;  1MMR A;  4ILW D;  3E8R A;  1G12 A;  4GR8 A;  1BKC I;  3KHI A;  1SLN A;  1IAE A;  1G05 A;  1PWV A;  1RMZ A;  2USN A;  1CAQ A;  3L0V A;  2TCL A;  4PKR A;  2OVX A;  1G49 A;  3B92 A;  3DPF A;  5L79 A;  1J7N A;  1BQO A;  1I73 A;  1XFY A;  1AST A;  2W12 A;  3F15 A;  1KUK A;  1YCM A;  3TVC A;  1CQR A;  4GQL A;  2W14 A;  2OW2 A;  3LIR A;  1PWU A;  3ZUK A;  3DTK A;  3TS4 A;  3DTI A;  1GE6 A;  1D8M A;  1QIB A;  1XUR A;  3KEK A;  2AYK A;  4FVL A;  1O0T A;  1ND1 A;  5LAB A;  4IUW A;  1I76 A;  1QIA A;  4I35 A;  1SRP A;  5D2B A;  456C A;  5JMY A;  2AIG P;  3HYG A;  2QPJ A;  4WZV A;  2JIH A;  2JT5 A;  3OHO A;  2XS4 A;  1HFS A;  4WKE A;  1SLM A;  1HV5 A;  1OZ9 A;  1JAQ A;  3O2X A;  3VI1 A;  1Y93 A;  3WV3 A;  2RJP A;  1K7G A;  4XCT A;  1A85 A;  2YUF A;  3EDH A;  3P1V A;  3DPE A;  3LK8 A;  1JKY A;  4HMA A;  1OMJ A;  1UTZ A;  1SU3 A;  2WO9 A;  4H49 A;  5I43 A;  1YQY A;  4PKW A;  2SRT A;  4QKZ A;  1QUA A;  3KWV C;  3TSK A;  4L63 A;  2OI0 A;  3TT4 A;  1IAA A;  3LE9 A;  4XBH A;  1BM6 A;  3L0T A;  1K7Q A;  1UMS A;  1IAG A;  1XFW A;  1A86 A;  3LIK A;  2JNP A;  1ROS A;  1Z3J A;  4GR3 A;  4GWN A;  2K9C A;  1TVI A;  2POJ A;  4H30 A;  1OO9 A;  4AIG A;  1ZXV A;  4JP4 A;  4A3W A;  4H84 A;  3UVC A;  1O0Q A;  2MZE A;  3I7I A;  3K7L A;  2I47 A;  4H2E A;  4GF1 A;  4WF6 A;  1IAD A;  1EAK A;  2WOA A;  1JK3 A;  3EHY A;  2W13 A;  3F1A A;  3LQ0 A;  2Z2D A;  1GE5 A;  4XM8 A;  3WV1 A;  3WV2 A;  1BUV M;  3KEC A;  1OM8 A;  5D1U A;  3USN A;  1PWQ A;  1QJJ A;  1KUG A;  4FU4 A;  3O64 A;  1D7X A;  3G42 A;  4J4M A;  1GE7 A;  1Q3A A;  2A8H A;  1QJI A;  2D1N A;  1MMP A;  3EDI A;  5I2Z A;  3V96 B;  1UTT A;  1XFU A;  1BKC A;  2K2G A;  5D7W A;  4L19 A;  1CIZ A;  3Q2H A;  1JJ9 A;  3BA0 A;  3HY7 A;  2XS3 A;  1L6J A;  4H3X A;  1JIW P;  4AYK A;  4PKU A;  1DTH A;  1GKD A;  4R3V A;  1ATL A;  4GR0 A;  1KBC A;  4I03 A;  1YP1 A;  2DW1 A;  2OW9 A;  1R1J A;  2DDF A;  2DDY A;  1ZP5 A;  5I12 A;  2MLS A;  4G9L A;  2L0R A;  2O3E A;  3LEA A;  2W15 A;  3AIG A;  4FXY P;  5D3C A;  2YIG A;  3B8Z A;  2Y6D A;  1Y8J A;  1HFC A;  1MNC A;  3LUM A;  2MZH A;  1GO8 P;  2V4B A;  4PKS A;  3VTG A;  4H76 A;  4H1Q A;  1D5J A;  3DL1 A;  3GBO A;  3F17 A;  1B3D A;  2HU6 A;  1CXV A;  1YOU A;  2X3B A;  3DNG A;  5BPA A;  4HX3 A;  1G4K A; 
#chains in the Genus database with same CATH homology
 2OXW A;  3B2Z A;  1AF0 A;  4XM6 A;  5B5O A;  3RTS A;  1HTD A;  3LJT A;  1C3I A;  4JIJ A;  3DTE A;  1BZS A;  4PKT A;  2OY2 A;  2CLT A;  5BOT A;  2N8R A;  4ON1 A;  4CTH A;  2X7M A;  3LJG A;  1JAO A;  4JA1 A;  1BIW A;  3F16 A;  2JSD A;  5I4O A;  3HBU P;  2PJT A;  1C7K A;  2D1O A;  3SHI A;  1CGF A;  1RM8 A;  1KUI A;  1KUF A;  3KME A;  1KUH A;  5I3M A;  1D8F A;  1SMP A;  3EHX A;  1C8T A;  3KMC A;  3LJZ A;  1SAT A;  2OW0 A;  5H8X A;  5B5P A;  3OHL A;  1ZTQ A;  3NX7 A;  4L6T A;  3ELM A;  1WNI A;  4DV8 A;  1PWW A;  4WKI A;  966C A;  3HDA P;  4DD8 A;  2X3C A;  3ZXH A;  5D1S A;  5CXA A;  2W0D A;  1G9K A;  1OS9 A;  1JAP A;  3KEJ A;  2ERP A;  3HY9 A;  2DW0 A;  1BKC E;  1K7I A;  3G5C A;  1ZS0 A;  3F19 A;  3HBV P;  1XUC A;  3F18 A;  3U1R A;  3AYK A;  1R1H A;  3P24 A;  3EWJ A;  2MLR A;  1CGE A;  1GXD A;  1XFX A;  2E3X A;  1JAN A;  1GKC A;  3LMC A;  1OS2 A;  1EB6 A;  4PKV A;  3HB2 P;  2OXU A;  1ZXC A;  4L7A A;  1R54 A;  1DMT A;  1XUD A;  1BQQ M;  5D1T A;  4A7B A;  1FM1 A;  5L7F A;  2RJQ A;  2J83 A;  3EDG A;  1FLS A;  1AYK A;  1PWP A;  1OM6 A;  1QIC A;  1XFV A;  2OW1 A;  2E2D A;  2OZR A;  3MA2 A;  4JQG A;  2OXZ A;  2FV9 A;  3LUN A;  4WK7 A;  3LGP A;  1KAP P;  1JIZ A;  1ZVX A;  4GWM A;  1OM7 A;  4G0D A;  1EUB A;  1Y0V A;  4GUY A;  4DF9 A;  4EFS A;  1GO7 P;  1BSW A;  3I7G A;  830C A;  2JT6 A;  1MMQ A;  1CGL A;  4H82 A;  4ZR5 A;  4AXQ A;  1JH1 A;  2ERQ A;  4AUO A;  3CKI A;  3N2U A;  1R55 A;  2YB9 A;  1UMT A;  3RTT A;  1UEA A;  1BUD A;  1MMB A;  5CUH A;  3LQB A;  2J0T A;  1IAC A;  2WO8 A;  3Q2G A;  4JPA A;  1H71 P;  4XM7 A;  5I0L A;  2ERO A;  2O36 A;  1S4B P;  1FBL A;  4IJO A;  1HOV A;  1R1I A;  3DWB A;  3EDZ A;  5BOY A;  1XFZ A;  1USN A;  2FV5 A;  3LIL A;  1HY7 A;  2Y6C A;  1IAB A;  4PKQ A;  1I1I P;  2OY4 A;  3KRY A;  4FXQ A;  2KRJ A;  5CZM A;  4IN9 A;  2CKI A;  3N2V A;  1B8Y A;  3K7N A;  3ZVS A;  2X3A A;  4DPE A;  2OVZ A;  3LKA A;  2MZI A;  3DSL A;  1CK7 A;  3AYU A;  4Q1L A;  1AKL A;  2DW2 A;  3HDB A;  1MMR A;  4ILW D;  3E8R A;  1G12 A;  4GR8 A;  1BKC I;  3KHI A;  1SLN A;  1IAE A;  1G05 A;  1PWV A;  1RMZ A;  2USN A;  1CAQ A;  3L0V A;  2TCL A;  4PKR A;  2OVX A;  1G49 A;  3B92 A;  3DPF A;  5L79 A;  1J7N A;  1BQO A;  1I73 A;  1XFY A;  1AST A;  2W12 A;  3F15 A;  1KUK A;  1YCM A;  3TVC A;  1CQR A;  4GQL A;  2W14 A;  2OW2 A;  3LIR A;  1PWU A;  3ZUK A;  3DTK A;  3TS4 A;  3DTI A;  1GE6 A;  1D8M A;  1QIB A;  1XUR A;  3KEK A;  2AYK A;  4FVL A;  1O0T A;  1ND1 A;  5LAB A;  4IUW A;  1I76 A;  1QIA A;  4I35 A;  1SRP A;  5D2B A;  456C A;  5JMY A;  2AIG P;  3HYG A;  2QPJ A;  4WZV A;  2JIH A;  2JT5 A;  3OHO A;  2XS4 A;  1HFS A;  4WKE A;  1SLM A;  1HV5 A;  1JAQ A;  3O2X A;  3VI1 A;  1Y93 A;  3WV3 A;  2RJP A;  1K7G A;  4XCT A;  1A85 A;  2YUF A;  3EDH A;  3P1V A;  3DPE A;  3LK8 A;  1JKY A;  4HMA A;  1OMJ A;  1UTZ A;  1SU3 A;  2WO9 A;  4H49 A;  5I43 A;  1YQY A;  4PKW A;  2SRT A;  4QKZ A;  1QUA A;  3KWV C;  3TSK A;  4L63 A;  2OI0 A;  3TT4 A;  1IAA A;  3LE9 A;  4XBH A;  1BM6 A;  3L0T A;  1K7Q A;  1UMS A;  1IAG A;  1XFW A;  1A86 A;  3LIK A;  2JNP A;  1ROS A;  1Z3J A;  4GR3 A;  4GWN A;  2K9C A;  4H30 A;  2POJ A;  1OO9 A;  4AIG A;  1ZXV A;  4JP4 A;  4A3W A;  4H84 A;  3UVC A;  1O0Q A;  2MZE A;  3I7I A;  3K7L A;  2I47 A;  4H2E A;  4GF1 A;  4WF6 A;  1IAD A;  1EAK A;  2WOA A;  1JK3 A;  3EHY A;  2W13 A;  3F1A A;  3LQ0 A;  2Z2D A;  1GE5 A;  4XM8 A;  3WV1 A;  3WV2 A;  1BUV M;  3KEC A;  1OM8 A;  5D1U A;  3USN A;  1PWQ A;  1QJJ A;  1KUG A;  4FU4 A;  3O64 A;  1D7X A;  3G42 A;  4J4M A;  1GE7 A;  1Q3A A;  2A8H A;  1QJI A;  2D1N A;  1MMP A;  3EDI A;  5I2Z A;  3V96 B;  1UTT A;  1XFU A;  1BKC A;  2K2G A;  5D7W A;  4L19 A;  1CIZ A;  3Q2H A;  1JJ9 A;  3BA0 A;  3HY7 A;  2XS3 A;  1L6J A;  4H3X A;  1JIW P;  4AYK A;  4PKU A;  1DTH A;  1GKD A;  4R3V A;  1ATL A;  4GR0 A;  1KBC A;  4I03 A;  1YP1 A;  2DW1 A;  2OW9 A;  1R1J A;  2DDF A;  2DDY A;  1ZP5 A;  5I12 A;  2MLS A;  4G9L A;  2L0R A;  2O3E A;  3LEA A;  2W15 A;  3AIG A;  4FXY P;  5D3C A;  2YIG A;  3B8Z A;  2Y6D A;  1Y8J A;  1HFC A;  1MNC A;  3LUM A;  2MZH A;  1GO8 P;  2V4B A;  4PKS A;  3VTG A;  4H76 A;  4H1Q A;  1D5J A;  3DL1 A;  3GBO A;  3F17 A;  1B3D A;  2HU6 A;  1CXV A;  1YOU A;  2X3B A;  3DNG A;  5BPA A;  4HX3 A;  1G4K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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