2V6UA

High resolution crystal structure of pterin-4a-carbinolamine dehydratase from toxoplasma gondii
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
103
structure length
103
Chain Sequence
MAPLARLAANSARLLQLHKTVPQWHLTDGHLSIKRKFQFSDFNEAWGFMSRVALYADKVDHHPNWYNVYNTVDVELSTHDAAGLTEKDFALAKFMDDAAKNFE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of Toxoplasma Gondii Pterin-4A-Carbinolamine Dehydratase and Comparisons with Mammalian and Parasite Orthologues.
pubmed doi rcsb
molecule tags Lyase
source organism Toxoplasma gondii
molecule keywords PTERIN-4A-CARBINOLAMINE DEHYDRATASE
total genus 32
structure length 103
sequence length 103
chains with identical sequence B
ec nomenclature ec 4.2.1.96: 4a-hydroxytetrahydrobiopterin dehydratase.
pdb deposition date 2007-07-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01329 Pterin_4a Pterin 4 alpha carbinolamine dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1360.20 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Transcriptional coactivator/pterin dehydratase 2v6uA00
1DCPA 2EBBA 1F93A 3JSTA 4WILA 1RU0A 2V6TA 2V6UA 4LOWA 3HXAA 1USOA 1DCHA 1USMA 2V6SA 1DCOA 4C45A
chains in the Genus database with same CATH superfamily
2EBBA 2NVYA 4A3KK 4BKWA 4A3DC 1J6VA 4AH6A 1VGXA 2ZFZA 3HOYK 5IYCC 2VUMA 2A6EA 4NOIA 4G7HA 3ERED 1G51A 1BGWA 4X6AC 3FOEA 5TJ3A 3GTKK 4C3JC 4G0VA 3GDZA 4Q4ZA 4A3IC 1K83K 1IQ0A 4P5BA 1IS1A 5C4XK 2NVXK 3S17C 4KASA 4A3FK 4PABA 4A3KC 2NVTK 1TWHA 2W7VA 1DCOA 4A3MC 1PJ7A 2E2HA 1TWCK 1TWFK 5JFEA 3JSTA 1TWGK 5C4XC 1SMYA 3M3YK 3S2HK 4LLGA 2JA5A 3HXAA 4A3FC 4A3GC 2NVTC 3BP8C 4G7OA 2RGRA 3BP3A 1SFOA 1YX2A 1R9TK 5EGEA 2PA8L 1WIHA 4BY1K 4ZH4A 2CFAB 2NVYC 2E2IA 1I6HK 1HI9A 3GTOK 5L46A 1TWFC 5M3FK 3PO3K 3HOZC 1I50A 5C4JK 1TWGC 4BXXK 3PO2K 1USMA 3M3YC 4MQ9A 2XCQA 3S2HC 2A69A 4FM9A 2GSOA 2JA6K 1R9TC 3AQPA 1XZPB 1I3QK 4GFQA 4BY1C 1J98A 1I6HC 1EH1A 1TWHC 1ZYRA 5C44K 4XLNA 4MEXA 1ZXOA 3PO3C 3GTLA 4GTEA 5C4JC 2R7ZA 3PO2C 2Y0SL 4BLBA 2WB1D 1IE0A 2JA5C 4KARA 3NUHA 2JA6C 3GTJA 3AH5A 4LJZA 1TWAK 1B4BA 1I3QC 4GTAA 4PAAA 1JQWA 1Y1VK 5C44C 3HKZL 1VLOA 3OEPA 5TMCA 1IBAA 1WOOA 3H3VL 1O2AA 2PA8D 1Y1WK 1I50C 1BJTA 2CFAA 1O2BA 1TWAC 1I6VA 1Y1VC 4OIPA 5M3MK 4GTBA 4J3NA 1XXAA 5IORA 4A3BC 3S16K 1Y1WC 4QIWD 2JA7K 4GT9A 3AD7C 1XZPA 2ZUEA 2V6SA 1WQHA 2NVXA 4LQYA 1EFWA 2JH3A 3N0BA 3GTJC 3ADAC 3AD8C 2O5IA 3GEHA 1WQGA 4LK1A 1XZQB 3I4NC 3T00A 2WAQD 3S16C 1XPPA 5IP7K 2ZUFA 2JA7C 2R92K 1TWFA 4OIQA 4LOWA 1TWGA 2GSNA 3AQOA 4A3CK 4OIOA 3S14C 1J6WA 4AYBL 3TFHA 4YFKA 1WCMK 3N3YA 4KB4A 1R9TA 1EK8A 3BUEA 1IL2A 2V6UA 5IOQA 3H0GK 3M4OK 1O25A 3GTOA 3FKIK 3HOYC 2R92C 4KM9A 3RZOK 4G0UA 3HOUK 4XLPA 2PMZL 3TFJA 1B4AA 1F93A 4P9SA 3GTKC 1WCMC 1K83C 2NVXC 3T02A 2JA6A 1WSRA 2P5MA 5E68A 1I3QA 3LAJA 3T01A 1DCHA 3H0GC 4C2MK 4BBSK 2Y3PA 4KDDA 3RZOC 4RMFA 1TWCC 3S1QK 1JVIA 1BS2A 1EI6A 1IW7A 3S15K 5M5YK 5FJ8K 1L0WA 1TWAA 2O5JA 1VRQC 4KATA 5M5WK 1Y1VA 3A8KA 3CAGA 3N0CA 2B63K 4G7ZA 3S1MC 3GTOC 1DCPA 1O2FB 3S1QC 1Y1WA 3GEEA 4A3JK 2GAHC 2R93K 4BXXC 5EGHA 3S1NK 4ILDA 4KN7A 1BDFA 2XCRB 4A3EK 2YU9K 4WILA 3GTMK 2B63C 3Q3QA 3S1RK 3A8IA 1JOEA 4OINA 1WQFA 2JA7A 4C3HK 4A3JC 1AB4A 4LK0A 4C3IK 3S1NC 4WJ4A 4FZBA 4A3EC 5CJ9A 3A8JA 4Y7NK 3GTQK 2YU9C 3MMLB 3DXJA 3GTMC 4XSZA 3S1RC 1O27A 4KB2A 3OREA 5IP9K 1GE9A 4BBRK 2R92A 4C3HC 4C3IC 3GTKA 4P5AA 1WCMA 1K83A 2R7ZK 2E2JK 1EQRA 5IYDK 3H0GA 2Y0SD 2XCOA 3S1MK 3CQZK 5IP9C 3S0XA 4GTDA 4KM8A 5CHPA 5D4DA 1TWCA 3SZYA 3HKZD 5IYBK 5IOSA 4YFNA 5M5XK 3L4JA 4Y52K 1V5VA 1WOSA 1WOPA 4X6AK 1UV7A 2E2JC 3H3VD 5C3EK 3TTGA 1DD5A 4A3IK 1YCLA 5IYDC 3V4GA 3HOXK 3GTGK 1VH2A 3CQZC 1YNJA 4QJVB 1O24A 5IP7C 3LAPA 5JVOA 1USOA 4A3MK 5IYBC 4Y52C 4A3CC 3GTPK 4KMUA 4BLAA 1WSVA 5C3EC 3VA7A 4G0WA 1HQMA 3HOXC 3GTGC 4M1XA 4XSXA 2CW0A 4KMHA 3I4MK 1XXBA 2B63A 4A3GK 2FQTA 4Q5SA 3M4OC 4JK1A 1RU0A 3LPXA 3FKIC 3G4AA 3AD9C 1WORA 2NVYK 3HOUC 3S2DK 2R93A 4BY7K 2RH6A 2WB1L 3OPFA 3GTPC 2VUMK 5FLMK 3HOZK 4KAWX 5IOTA 1XZQA 2YU9A 3I4MC 3GTMA 2PPBA 1O26A 4C2MC 4BBSC 2FQOA 3SZZA 4AYBD 4GTFA 1YNNA 1TWHK 1PJ5A 3S2DC 4BY7C 4KN4A 2VUMC 5FLMC 2E2HK 4KMDA 3S15C 1PJ6A 3GTQA 4WJ3M 1O28A 4QJVA 3IPJA 1ZQ1C 2PMZD 2JA5K 3G4CA 3HOVK 3QX3A 4QIWL 2D6FC 2BE5A 2KWAA 1SFOK 2NVQK 1ZVUA 2E2IK 5HL8A 2E2HC 1XXCA 2R93C 1J6XA 2GSUA 3GIRA 2A68A 1ZBSA 1I50K 2GAGC 4A93K 1VJEA 2WAQL 1F7VA 4KC6A 3HOVC 3CQZA 4A3LK 1KQ4A 4O2DA 2JA8K 3FOFA 1SFOC 2NVQC 2E2IC 4DDQA 3TFIA 3L4KA 4A3BK 2V6TA 3GTLK 1X31C 3K7AK 4Y7NC 3GTQC 2PHCB 3HOWK 4A93C 1O29A 4GZYA 3GTGA 4LR2A 4C45A 4YFXA 3EQLA 4A3LC 2JA8C 3RZDK 4XCHA 3GTJK 1ISEA 4GTLA 3FKIA 4BBRC 3WODA 4A3DK 3I4NK 2P8TA 3FHZA 4OIRA 3GTPA 3GTLC 5IYCK 1C0AA 2R7ZC 3K7AC 4YG2A 3HOWC 2A6HA 3GSIA 3S14K 4C3JK 4GTCA 1INNA 3S17K 3RZDC 3GEIA 4KMAA 4MEYA 5TMFA 1F7UA 1F9NA
chains in the Genus database with same CATH topology
1DCPA 2EBBA 1F93A 3JSTA 4WILA 1RU0A 2V6TA 2V6UA 4LOWA 3HXAA 1USOA 1DCHA 1USMA 2V6SA 1DCOA 4C45A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DCP A;  2EBB A;  1F93 A;  3JST A;  4WIL A;  1RU0 A;  2V6T A;  2V6U A;  4LOW A;  3HXA A;  1USO A;  1DCH A;  1USM A;  2V6S A;  1DCO A;  4C45 A; 
#chains in the Genus database with same CATH topology
 2EBB A;  2NVY A;  4A3K K;  4BKW A;  4A3D C;  1J6V A;  4AH6 A;  1VGX A;  2ZFZ A;  3HOY K;  5IYC C;  2VUM A;  2A6E A;  4NOI A;  4G7H A;  3ERE D;  1G51 A;  1BGW A;  4X6A C;  3FOE A;  5TJ3 A;  3GTK K;  4C3J C;  4G0V A;  3GDZ A;  4Q4Z A;  4A3I C;  1K83 K;  1IQ0 A;  4P5B A;  1IS1 A;  5C4X K;  2NVX K;  3S17 C;  4KAS A;  4A3F K;  4PAB A;  4A3K C;  2NVT K;  1TWH A;  2W7V A;  1DCO A;  4A3M C;  1PJ7 A;  2E2H A;  1TWC K;  1TWF K;  5JFE A;  3JST A;  1TWG K;  5C4X C;  1SMY A;  3M3Y K;  3S2H K;  4LLG A;  2JA5 A;  3HXA A;  4A3F C;  4A3G C;  2NVT C;  3BP8 C;  4G7O A;  2RGR A;  3BP3 A;  1SFO A;  1YX2 A;  1R9T K;  5EGE A;  2PA8 L;  1WIH A;  4BY1 K;  4ZH4 A;  2CFA B;  2NVY C;  2E2I A;  1I6H K;  1HI9 A;  3GTO K;  5L46 A;  1TWF C;  5M3F K;  3PO3 K;  3HOZ C;  1I50 A;  5C4J K;  1TWG C;  4BXX K;  3PO2 K;  1USM A;  3M3Y C;  4MQ9 A;  2XCQ A;  3S2H C;  2A69 A;  4FM9 A;  2GSO A;  2JA6 K;  1R9T C;  3AQP A;  1XZP B;  1I3Q K;  4GFQ A;  4BY1 C;  1J98 A;  1I6H C;  1EH1 A;  1TWH C;  1ZYR A;  5C44 K;  4XLN A;  4MEX A;  1ZXO A;  3PO3 C;  3GTL A;  4GTE A;  5C4J C;  2R7Z A;  3PO2 C;  2Y0S L;  4BLB A;  2WB1 D;  1IE0 A;  2JA5 C;  4KAR A;  3NUH A;  2JA6 C;  3GTJ A;  3AH5 A;  4LJZ A;  1TWA K;  1B4B A;  1I3Q C;  4GTA A;  4PAA A;  1JQW A;  1Y1V K;  5C44 C;  3HKZ L;  1VLO A;  3OEP A;  5TMC A;  1IBA A;  1WOO A;  3H3V L;  1O2A A;  2PA8 D;  1Y1W K;  1I50 C;  1BJT A;  2CFA A;  1O2B A;  1TWA C;  1I6V A;  1Y1V C;  4OIP A;  5M3M K;  4GTB A;  4J3N A;  1XXA A;  5IOR A;  4A3B C;  3S16 K;  1Y1W C;  4QIW D;  2JA7 K;  4GT9 A;  3AD7 C;  1XZP A;  2ZUE A;  2V6S A;  1WQH A;  2NVX A;  4LQY A;  1EFW A;  2JH3 A;  3N0B A;  3GTJ C;  3ADA C;  3AD8 C;  2O5I A;  3GEH A;  1WQG A;  4LK1 A;  1XZQ B;  3I4N C;  3T00 A;  2WAQ D;  3S16 C;  1XPP A;  5IP7 K;  2ZUF A;  2JA7 C;  2R92 K;  1TWF A;  4OIQ A;  4LOW A;  1TWG A;  2GSN A;  3AQO A;  4A3C K;  4OIO A;  3S14 C;  1J6W A;  4AYB L;  3TFH A;  4YFK A;  1WCM K;  3N3Y A;  4KB4 A;  1R9T A;  1EK8 A;  3BUE A;  1IL2 A;  2V6U A;  5IOQ A;  3H0G K;  3M4O K;  1O25 A;  3GTO A;  3FKI K;  3HOY C;  2R92 C;  4KM9 A;  3RZO K;  4G0U A;  3HOU K;  4XLP A;  2PMZ L;  3TFJ A;  1B4A A;  1F93 A;  4P9S A;  3GTK C;  1WCM C;  1K83 C;  2NVX C;  3T02 A;  2JA6 A;  1WSR A;  2P5M A;  5E68 A;  1I3Q A;  3LAJ A;  3T01 A;  1DCH A;  3H0G C;  4C2M K;  4BBS K;  2Y3P A;  4KDD A;  3RZO C;  4RMF A;  1TWC C;  3S1Q K;  1JVI A;  1BS2 A;  1EI6 A;  1IW7 A;  3S15 K;  5M5Y K;  5FJ8 K;  1L0W A;  1TWA A;  2O5J A;  1VRQ C;  4KAT A;  5M5W K;  1Y1V A;  3A8K A;  3CAG A;  3N0C A;  2B63 K;  4G7Z A;  3S1M C;  3GTO C;  1DCP A;  1O2F B;  3S1Q C;  1Y1W A;  3GEE A;  4A3J K;  2GAH C;  2R93 K;  4BXX C;  5EGH A;  3S1N K;  4ILD A;  4KN7 A;  1BDF A;  2XCR B;  4A3E K;  2YU9 K;  4WIL A;  3GTM K;  2B63 C;  3Q3Q A;  3S1R K;  3A8I A;  1JOE A;  4OIN A;  1WQF A;  2JA7 A;  4C3H K;  4A3J C;  1AB4 A;  4LK0 A;  4C3I K;  3S1N C;  4WJ4 A;  4FZB A;  4A3E C;  5CJ9 A;  3A8J A;  4Y7N K;  3GTQ K;  2YU9 C;  3MML B;  3DXJ A;  3GTM C;  4XSZ A;  3S1R C;  1O27 A;  4KB2 A;  3ORE A;  5IP9 K;  1GE9 A;  4BBR K;  2R92 A;  4C3H C;  4C3I C;  3GTK A;  4P5A A;  1WCM A;  1K83 A;  2R7Z K;  2E2J K;  1EQR A;  5IYD K;  3H0G A;  2Y0S D;  2XCO A;  3S1M K;  3CQZ K;  5IP9 C;  3S0X A;  4GTD A;  4KM8 A;  5CHP A;  5D4D A;  1TWC A;  3SZY A;  3HKZ D;  5IYB K;  5IOS A;  4YFN A;  5M5X K;  3L4J A;  4Y52 K;  1V5V A;  1WOS A;  1WOP A;  4X6A K;  1UV7 A;  2E2J C;  3H3V D;  5C3E K;  3TTG A;  1DD5 A;  4A3I K;  1YCL A;  5IYD C;  3V4G A;  3HOX K;  3GTG K;  1VH2 A;  3CQZ C;  1YNJ A;  4QJV B;  1O24 A;  5IP7 C;  3LAP A;  5JVO A;  1USO A;  4A3M K;  5IYB C;  4Y52 C;  4A3C C;  3GTP K;  4KMU A;  4BLA A;  1WSV A;  5C3E C;  3VA7 A;  4G0W A;  1HQM A;  3HOX C;  3GTG C;  4M1X A;  4XSX A;  2CW0 A;  4KMH A;  3I4M K;  1XXB A;  2B63 A;  4A3G K;  2FQT A;  4Q5S A;  3M4O C;  4JK1 A;  1RU0 A;  3LPX A;  3FKI C;  3G4A A;  3AD9 C;  1WOR A;  2NVY K;  3HOU C;  3S2D K;  2R93 A;  4BY7 K;  2RH6 A;  2WB1 L;  3OPF A;  3GTP C;  2VUM K;  5FLM K;  3HOZ K;  4KAW X;  5IOT A;  1XZQ A;  2YU9 A;  3I4M C;  3GTM A;  2PPB A;  1O26 A;  4C2M C;  4BBS C;  2FQO A;  3SZZ A;  4AYB D;  4GTF A;  1YNN A;  1TWH K;  1PJ5 A;  3S2D C;  4BY7 C;  4KN4 A;  2VUM C;  5FLM C;  2E2H K;  4KMD A;  3S15 C;  1PJ6 A;  3GTQ A;  4WJ3 M;  1O28 A;  4QJV A;  3IPJ A;  1ZQ1 C;  2PMZ D;  2JA5 K;  3G4C A;  3HOV K;  3QX3 A;  4QIW L;  2D6F C;  2BE5 A;  2KWA A;  1SFO K;  2NVQ K;  1ZVU A;  2E2I K;  5HL8 A;  2E2H C;  1XXC A;  2R93 C;  1J6X A;  2GSU A;  3GIR A;  2A68 A;  1ZBS A;  1I50 K;  2GAG C;  4A93 K;  1VJE A;  2WAQ L;  1F7V A;  4KC6 A;  3HOV C;  3CQZ A;  4A3L K;  1KQ4 A;  4O2D A;  2JA8 K;  3FOF A;  1SFO C;  2NVQ C;  2E2I C;  4DDQ A;  3TFI A;  3L4K A;  4A3B K;  2V6T A;  3GTL K;  1X31 C;  3K7A K;  4Y7N C;  3GTQ C;  2PHC B;  3HOW K;  4A93 C;  1O29 A;  4GZY A;  3GTG A;  4LR2 A;  4C45 A;  4YFX A;  3EQL A;  4A3L C;  2JA8 C;  3RZD K;  4XCH A;  3GTJ K;  1ISE A;  4GTL A;  3FKI A;  4BBR C;  3WOD A;  4A3D K;  3I4N K;  2P8T A;  3FHZ A;  4OIR A;  3GTP A;  3GTL C;  5IYC K;  1C0A A;  2R7Z C;  3K7A C;  4YG2 A;  3HOW C;  2A6H A;  3GSI A;  3S14 K;  4C3J K;  4GTC A;  1INN A;  3S17 K;  3RZD C;  3GEI A;  4KMA A;  4MEY A;  5TMF A;  1F7U A;  1F9N A; 
#chains in the Genus database with same CATH homology
 1DCP A;  2EBB A;  1F93 A;  3JST A;  4WIL A;  1RU0 A;  2V6T A;  2V6U A;  4LOW A;  3HXA A;  1USO A;  1DCH A;  1USM A;  2V6S A;  1DCO A;  4C45 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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