2V7DA

14-3-3 protein zeta in complex with thr758 phosphorylated integrin beta2 peptide
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
231
structure length
228
Chain Sequence
GSMDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Beta2 Integrin Phosphorylation on Thr758 Acts as a Molecular Switch to Regulate 14-3-3 and Filamin Binding.
pubmed doi rcsb
molecule tags Signaling protein
source organism Bos taurus
molecule keywords 14-3-3 PROTEIN ZETA/DELTA
total genus 93
structure length 228
sequence length 231
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2007-07-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 2v7dA00
4DATA 4QLIA 2C1JA 4BG6A 1QJAA 3P1OA 3EFZA 4DHPA 1A38A 4HKCA 4Y5IA 5IQPA 3M51A 3SMLA 4N7YA 1IB1A 3SMKA 1YWTA 5LU1A 3E6YA 3SPRA 4DHNA 2O02A 3UZDA 3UX0A 4IHLA 1QJBA 4DHOA 2C74A 2BTPA 3U9XA 5HF3A 5D2DA 3P1PA 4E2EA 3UALA 3IQUA 3AXYC 3LW1A 4J6SA 5EWZA 4Y3BA 3IQVA 4DHQA 2O98A 5BY9A 4DHSA 3SMOA 4JDDA 4ZQ0A 4DHTA 5LU2A 5D3EA 5LX2A 4N84A 5J31A 1O9CA 1A4OA 2BR9A 1YZ5A 4IEAA 3SMNA 2C63A 4JC3A 5F74A 4F7RA 3O8IA 5LVZA 2WH0A 5D3FA 3IQJA 3M50A 3P1QA 4FJ3A 3SMMA 4DHRA 4DX0A 3UBWA 3P1RA 4Y32A 3RDHA 3T0MA 1O9EA 3MHRA 4DHMA 5LHOA 3P1NA 5EXAA 2C23A 4FR3A 1O9DA 4N7GA 4WRQA 5BTVA 4GNTA 4O46A 1A37A 1O9FA 2C1NA 2BQ0A 4ZDRA 4FL5A 3NKXA 4DAUA 4DHUA 4DNKA 2B05A 3SP5A 2O8PA 3CU8A 2V7DA 3P1SA 2NPMA 3T0LA
chains in the Genus database with same CATH superfamily
4DATA 4QLIA 2C1JA 4BG6A 1QJAA 3P1OA 3EFZA 4DHPA 4D8MA 1A38A 4HKCA 1I5PA 4Y5IA 5IQPA 3M51A 3SMLA 4N7YA 4ARYA 3I4RA 4QX1A 1IB1A 3SMKA 1YWTA 5LU1A 3E6YA 3SPRA 4DHNA 2O02A 3UZDA 3UX0A 4IHLA 1QJBA 4DHOA 2C74A 2BTPA 3CQCA 1JI6A 3U9XA 5HF3A 1DLCA 5D2DA 4MOAA 3P1PA 3CQGA 4E2EA 3UALA 3IQUA 3AXYC 3LW1A 4J6SA 5EWZA 4ARXA 4Y3BA 3IQVA 1S2XA 4DHQA 2O98A 5BY9A 2C9KA 4DHSA 3SMOA 4QX2A 4JDDA 4ZQ0A 4DHTA 5LU2A 5D3EA 5LX2A 4N84A 5J31A 1O9CA 1A4OA 2BR9A 1YZ5A 4IEAA 3SMNA 2C63A 4JC3A 5F74A 4F7RA 3ZHEB 3O8IA 5LVZA 2WH0A 5D3FA 1URJA 3IQJA 3M50A 3P1QA 4FJ3A 3SMMA 4DHRA 4DX0A 3EB7A 3UBWA 3P1RA 4Y32A 3RDHA 3T0MA 3X0UA 1O9EA 1CIYA 3MHRA 4DHMA 5LHOA 3P1NA 5EXAA 2C23A 4FR3A 4QX3A 1O9DA 4N7GA 4WRQA 5BTVA 4GNTA 4O46A 1A37A 1O9FA 2C1NA 4QX0A 2BQ0A 4ZDRA 4FL5A 3NKXA 4DAUA 4DHUA 4DNKA 2B05A 3SP5A 2O8PA 3CU8A 2V7DA 3P1SA 2NPMA 3T0LA 4W8JA 1W99A
chains in the Genus database with same CATH topology
4DATA 4QLIA 2C1JA 4BG6A 1QJAA 3P1OA 3EFZA 4DHPA 1A38A 4HKCA 4Y5IA 5IQPA 3M51A 3SMLA 4N7YA 1IB1A 3SMKA 1YWTA 5LU1A 3E6YA 3SPRA 4DHNA 2O02A 3UZDA 3UX0A 4IHLA 1QJBA 4DHOA 2C74A 2BTPA 3U9XA 5HF3A 5D2DA 3P1PA 4E2EA 3UALA 3IQUA 3AXYC 3LW1A 4J6SA 5EWZA 4Y3BA 3IQVA 4DHQA 2O98A 5BY9A 4DHSA 3SMOA 4JDDA 4ZQ0A 4DHTA 5LU2A 5D3EA 5LX2A 4N84A 5J31A 1O9CA 1A4OA 2BR9A 1YZ5A 4IEAA 3SMNA 2C63A 4JC3A 5F74A 4F7RA 3O8IA 5LVZA 2WH0A 5D3FA 3IQJA 3M50A 3P1QA 4FJ3A 3SMMA 4DHRA 4DX0A 3UBWA 3P1RA 4Y32A 3RDHA 3T0MA 1O9EA 3MHRA 4DHMA 5LHOA 3P1NA 5EXAA 2C23A 4FR3A 1O9DA 4N7GA 4WRQA 5BTVA 4GNTA 4O46A 1A37A 1O9FA 2C1NA 2BQ0A 4ZDRA 4FL5A 3NKXA 4DAUA 4DHUA 4DNKA 2B05A 3SP5A 2O8PA 3CU8A 2V7DA 3P1SA 2NPMA 3T0LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DAT A;  4QLI A;  2C1J A;  4BG6 A;  1QJA A;  3P1O A;  3EFZ A;  4DHP A;  1A38 A;  4HKC A;  4Y5I A;  5IQP A;  3M51 A;  3SML A;  4N7Y A;  1IB1 A;  3SMK A;  1YWT A;  5LU1 A;  3E6Y A;  3SPR A;  4DHN A;  2O02 A;  3UZD A;  3UX0 A;  4IHL A;  1QJB A;  4DHO A;  2C74 A;  2BTP A;  3U9X A;  5HF3 A;  5D2D A;  3P1P A;  4E2E A;  3UAL A;  3IQU A;  3AXY C;  3LW1 A;  4J6S A;  5EWZ A;  4Y3B A;  3IQV A;  4DHQ A;  2O98 A;  5BY9 A;  4DHS A;  3SMO A;  4JDD A;  4ZQ0 A;  4DHT A;  5LU2 A;  5D3E A;  5LX2 A;  4N84 A;  5J31 A;  1O9C A;  1A4O A;  2BR9 A;  1YZ5 A;  4IEA A;  3SMN A;  2C63 A;  4JC3 A;  5F74 A;  4F7R A;  3O8I A;  5LVZ A;  2WH0 A;  5D3F A;  3IQJ A;  3M50 A;  3P1Q A;  4FJ3 A;  3SMM A;  4DHR A;  4DX0 A;  3UBW A;  3P1R A;  4Y32 A;  3RDH A;  3T0M A;  1O9E A;  3MHR A;  4DHM A;  5LHO A;  3P1N A;  5EXA A;  2C23 A;  4FR3 A;  1O9D A;  4N7G A;  4WRQ A;  5BTV A;  4GNT A;  4O46 A;  1A37 A;  1O9F A;  2C1N A;  2BQ0 A;  4ZDR A;  4FL5 A;  3NKX A;  4DAU A;  4DHU A;  4DNK A;  2B05 A;  3SP5 A;  2O8P A;  3CU8 A;  2V7D A;  3P1S A;  2NPM A;  3T0L A; 
#chains in the Genus database with same CATH topology
 4DAT A;  4QLI A;  2C1J A;  4BG6 A;  1QJA A;  3P1O A;  3EFZ A;  4DHP A;  4D8M A;  1A38 A;  4HKC A;  1I5P A;  4Y5I A;  5IQP A;  3M51 A;  3SML A;  4N7Y A;  4ARY A;  3I4R A;  4QX1 A;  1IB1 A;  3SMK A;  1YWT A;  5LU1 A;  3E6Y A;  3SPR A;  4DHN A;  2O02 A;  3UZD A;  3UX0 A;  4IHL A;  1QJB A;  4DHO A;  2C74 A;  2BTP A;  3CQC A;  1JI6 A;  3U9X A;  5HF3 A;  1DLC A;  5D2D A;  4MOA A;  3P1P A;  3CQG A;  4E2E A;  3UAL A;  3IQU A;  3AXY C;  3LW1 A;  4J6S A;  5EWZ A;  4ARX A;  4Y3B A;  3IQV A;  1S2X A;  4DHQ A;  2O98 A;  5BY9 A;  2C9K A;  4DHS A;  3SMO A;  4QX2 A;  4JDD A;  4ZQ0 A;  4DHT A;  5LU2 A;  5D3E A;  5LX2 A;  4N84 A;  5J31 A;  1O9C A;  1A4O A;  2BR9 A;  1YZ5 A;  4IEA A;  3SMN A;  2C63 A;  4JC3 A;  5F74 A;  4F7R A;  3ZHE B;  3O8I A;  5LVZ A;  2WH0 A;  5D3F A;  1URJ A;  3IQJ A;  3M50 A;  3P1Q A;  4FJ3 A;  3SMM A;  4DHR A;  4DX0 A;  3EB7 A;  3UBW A;  3P1R A;  4Y32 A;  3RDH A;  3T0M A;  3X0U A;  1O9E A;  1CIY A;  3MHR A;  4DHM A;  5LHO A;  3P1N A;  5EXA A;  2C23 A;  4FR3 A;  4QX3 A;  1O9D A;  4N7G A;  4WRQ A;  5BTV A;  4GNT A;  4O46 A;  1A37 A;  1O9F A;  2C1N A;  4QX0 A;  2BQ0 A;  4ZDR A;  4FL5 A;  3NKX A;  4DAU A;  4DHU A;  4DNK A;  2B05 A;  3SP5 A;  2O8P A;  3CU8 A;  2V7D A;  3P1S A;  2NPM A;  3T0L A;  4W8J A;  1W99 A; 
#chains in the Genus database with same CATH homology
 4DAT A;  4QLI A;  2C1J A;  4BG6 A;  1QJA A;  3P1O A;  3EFZ A;  4DHP A;  1A38 A;  4HKC A;  4Y5I A;  5IQP A;  3M51 A;  3SML A;  4N7Y A;  1IB1 A;  3SMK A;  1YWT A;  5LU1 A;  3E6Y A;  3SPR A;  4DHN A;  2O02 A;  3UZD A;  3UX0 A;  4IHL A;  1QJB A;  4DHO A;  2C74 A;  2BTP A;  3U9X A;  5HF3 A;  5D2D A;  3P1P A;  4E2E A;  3UAL A;  3IQU A;  3AXY C;  3LW1 A;  4J6S A;  5EWZ A;  4Y3B A;  3IQV A;  4DHQ A;  2O98 A;  5BY9 A;  4DHS A;  3SMO A;  4JDD A;  4ZQ0 A;  4DHT A;  5LU2 A;  5D3E A;  5LX2 A;  4N84 A;  5J31 A;  1O9C A;  1A4O A;  2BR9 A;  1YZ5 A;  4IEA A;  3SMN A;  2C63 A;  4JC3 A;  5F74 A;  4F7R A;  3O8I A;  5LVZ A;  2WH0 A;  5D3F A;  3IQJ A;  3M50 A;  3P1Q A;  4FJ3 A;  3SMM A;  4DHR A;  4DX0 A;  3UBW A;  3P1R A;  4Y32 A;  3RDH A;  3T0M A;  1O9E A;  3MHR A;  4DHM A;  5LHO A;  3P1N A;  5EXA A;  2C23 A;  4FR3 A;  1O9D A;  4N7G A;  4WRQ A;  5BTV A;  4GNT A;  4O46 A;  1A37 A;  1O9F A;  2C1N A;  2BQ0 A;  4ZDR A;  4FL5 A;  3NKX A;  4DAU A;  4DHU A;  4DNK A;  2B05 A;  3SP5 A;  2O8P A;  3CU8 A;  2V7D A;  3P1S A;  2NPM A;  3T0L A; 
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