2V92A

Crystal structure of the regulatory fragment of mammalian ampk in complexes with atp-amp
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
156
structure length
102
Chain Sequence
SMAWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDEVAPRPGSHTIEFFEMCANLIKILAQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
pubmed doi rcsb
molecule keywords 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1
molecule tags Transferase
source organism Rattus norvegicus
total genus 21
structure length 102
sequence length 156
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2007-08-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.80 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Kinase associated domain 1, KA1 2v92A01
3T4NA 4EAKA 2V92A 2OOYA 2QLVA 2OOXA 3TDHA 1UL7A 1V5SA 4EAIA 2YA3A 2V8QA 2EHBD 2Y8LA 2QRCA 2QR1A 4EAJA 4EALA 3OSEA 2V9JA 3TE5A 4CFFA 2ZFDB 2Y8QA 2QRDA 4EAGA 2QREA
chains in the Genus database with same CATH superfamily
3T4NA 4EAKA 1QN4A 2JHJA 1C9BB 2OOYA 3F0ZA 3OSTA 5JN5A 3OH6A 4EJYA 3SNSA 5IYCP 1DIZA 3CVTA 2QLVA 2VJ0A 2XHIA 2HZMA 1EBMA 1R4XA 3DPUA 2Z8UA 2NOHA 2NOFA 2HL8A 2NWVA 3EAYA 1MP9A 1QN6A 2FKFA 1E42A 2MJ7A 3EIKA 3PMGA 1KYUA 1YQMA 3OGDA 1LWWA 1CDWA 1VKLA 3ASMA 4RODB 4BJUA 4MRQA 3KTUA 1LWYA 4B0AA 2G30A 1KY6A 5BMNA 1PCJX 1KY7A 1M3HA 1Q9UA 3RPJA 4ROEB 3ULXA 1B9KA 1T6AA 1KFIA 1YQRA 2D0BA 3C04A 4EJZA 2HZSA 2IV9A 1LXTA 1HU0A 1UT4A 1PZDA 1M3QA 1QN7A 2LAEA 1QNAA 1QN9A 2JOIA 3OCIA 3CWUA 1QNBA 3TDHA 3ENCA 4PY5A 2H5AX 2FGTA 1C4GA 5IYDP 3OC3C 1K2YX 2HL9A 1KFQA 2I5WA 2NOBA 3CWTA 2R5XA 2F7LA 2EHBD 2JHNA 1QN8A 1QNEA 2QR1A 4D7QA 2NLVA 4EALA 2PWWA 3OSEA 4TPSA 1N3AA 3TE5A 3VN5A 5KL0A 3HS8A 2NOEA 2Y8QA 1JDYA 3UW2A 1LWVA 1WQAA 2NOZA 1J3MA 1KYDA 4D7RA 1QTSA 1TBPA 2D0AA 1QNCA 1KYFA 2O3OA 4QG5A 4WXAA 1M5Q1 2D0CA 2MZ8A 4WX8A 4I8OA 2OOXA 1PVSA 1VOKA 1QTPA 1UL7A 1C47A 3ENOC 1V5SA 1WJWA 2HKPA 2NOLA 4EAIA 1NH2A 3F10A 1KO9A 4IL8A 3D7QA 3DPTA 2QRCA 5HSHA 2YH5A 3OLPA 2DKDA 1W80A 1EUVA 3RSMA 2V9JA 1D3UA 1VOLB 4ROCB 4CFFA 1QN3A 3CWSA 5IYBP 2Z0FA 2H4LX 3BKQX 2QREA 3I0XA 1YQKA 1YQLA 1TGHA 1TUOA 2V92A 1YTFA 1VTOA 5EPCA 1RM1A 1UT7A 1VTLE 3CWAA 2FKMX 3PDKA 1NGMA 5F9CA 1NVPA 1PCMX 2DKAA 3NA5A 2NVMA 4HJHA 4WZSD 2IV8A 4Q11A 1AISA 1K35A 2NOIA 1QN5A 3HS9A 1N3CA 1JFIC 3H1ZA 3CVSA 2FUVA 2YA3A 2V8QA 2Y8LA 2DKCA 5AN4A 5JMVD 1FN7A 2JPIA 1PCZA 3D4VA 4EAJA 1P5DX 3OSMA 5BMPA 4DULA 3CW7A 3KRMA 3I3WA 3I0WA 3N89A 2ZFDB 3IH7A 1P5GX 1TBAB 2QRDA 1MPGA 3OH9A 1N39A 4EAGA 1XSZA 1YTBA 4C7PA
chains in the Genus database with same CATH topology
3T4NA 4EAKA 2V92A 2OOYA 2QLVA 2OOXA 3TDHA 1UL7A 1V5SA 4EAIA 2YA3A 2V8QA 2EHBD 2Y8LA 2QRCA 2QR1A 4EAJA 4EALA 3OSEA 2V9JA 3TE5A 4CFFA 2ZFDB 2Y8QA 2QRDA 4EAGA 2QREA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T4N A;  4EAK A;  2V92 A;  2OOY A;  2QLV A;  2OOX A;  3TDH A;  1UL7 A;  1V5S A;  4EAI A;  2YA3 A;  2V8Q A;  2EHB D;  2Y8L A;  2QRC A;  2QR1 A;  4EAJ A;  4EAL A;  3OSE A;  2V9J A;  3TE5 A;  4CFF A;  2ZFD B;  2Y8Q A;  2QRD A;  4EAG A;  2QRE A; 
#chains in the Genus database with same CATH topology
 3T4N A;  4EAK A;  1QN4 A;  2JHJ A;  1C9B B;  2OOY A;  3F0Z A;  3OST A;  5JN5 A;  3OH6 A;  4EJY A;  3SNS A;  5IYC P;  1DIZ A;  3CVT A;  2QLV A;  2VJ0 A;  2XHI A;  2HZM A;  1EBM A;  1R4X A;  3DPU A;  2Z8U A;  2NOH A;  2NOF A;  2HL8 A;  2NWV A;  3EAY A;  1MP9 A;  1QN6 A;  2FKF A;  1E42 A;  2MJ7 A;  3EIK A;  3PMG A;  1KYU A;  1YQM A;  3OGD A;  1LWW A;  1CDW A;  1VKL A;  3ASM A;  4ROD B;  4BJU A;  4MRQ A;  3KTU A;  1LWY A;  4B0A A;  2G30 A;  1KY6 A;  5BMN A;  1PCJ X;  1KY7 A;  1M3H A;  1Q9U A;  3RPJ A;  4ROE B;  3ULX A;  1B9K A;  1T6A A;  1KFI A;  1YQR A;  2D0B A;  3C04 A;  4EJZ A;  2HZS A;  2IV9 A;  1LXT A;  1HU0 A;  1UT4 A;  1PZD A;  1M3Q A;  1QN7 A;  2LAE A;  1QNA A;  1QN9 A;  2JOI A;  3OCI A;  3CWU A;  1QNB A;  3TDH A;  3ENC A;  4PY5 A;  2H5A X;  2FGT A;  1C4G A;  5IYD P;  3OC3 C;  1K2Y X;  2HL9 A;  1KFQ A;  2I5W A;  2NOB A;  3CWT A;  2R5X A;  2F7L A;  2EHB D;  2JHN A;  1QN8 A;  1QNE A;  2QR1 A;  4D7Q A;  2NLV A;  4EAL A;  2PWW A;  3OSE A;  4TPS A;  1N3A A;  3TE5 A;  3VN5 A;  5KL0 A;  3HS8 A;  2NOE A;  2Y8Q A;  1JDY A;  3UW2 A;  1LWV A;  1WQA A;  2NOZ A;  1J3M A;  1KYD A;  4D7R A;  1QTS A;  1TBP A;  2D0A A;  1QNC A;  1KYF A;  2O3O A;  4QG5 A;  4WXA A;  1M5Q 1;  2D0C A;  2MZ8 A;  4WX8 A;  4I8O A;  2OOX A;  1PVS A;  1VOK A;  1QTP A;  1UL7 A;  1C47 A;  3ENO C;  1V5S A;  1WJW A;  2HKP A;  2NOL A;  4EAI A;  1NH2 A;  3F10 A;  1KO9 A;  4IL8 A;  3D7Q A;  3DPT A;  2QRC A;  5HSH A;  2YH5 A;  3OLP A;  2DKD A;  1W80 A;  1EUV A;  3RSM A;  2V9J A;  1D3U A;  1VOL B;  4ROC B;  4CFF A;  1QN3 A;  3CWS A;  5IYB P;  2Z0F A;  2H4L X;  3BKQ X;  2QRE A;  3I0X A;  1YQK A;  1YQL A;  1TGH A;  1TUO A;  2V92 A;  1YTF A;  1VTO A;  5EPC A;  1RM1 A;  1UT7 A;  1VTL E;  3CWA A;  2FKM X;  3PDK A;  1NGM A;  5F9C A;  1NVP A;  1PCM X;  2DKA A;  3NA5 A;  2NVM A;  4HJH A;  4WZS D;  2IV8 A;  4Q11 A;  1AIS A;  1K35 A;  2NOI A;  1QN5 A;  3HS9 A;  1N3C A;  1JFI C;  3H1Z A;  3CVS A;  2FUV A;  2YA3 A;  2V8Q A;  2Y8L A;  2DKC A;  5AN4 A;  5JMV D;  1FN7 A;  2JPI A;  1PCZ A;  3D4V A;  4EAJ A;  1P5D X;  3OSM A;  5BMP A;  4DUL A;  3CW7 A;  3KRM A;  3I3W A;  3I0W A;  3N89 A;  2ZFD B;  3IH7 A;  1P5G X;  1TBA B;  2QRD A;  1MPG A;  3OH9 A;  1N39 A;  4EAG A;  1XSZ A;  1YTB A;  4C7P A; 
#chains in the Genus database with same CATH homology
 3T4N A;  4EAK A;  2V92 A;  2OOY A;  2QLV A;  2OOX A;  3TDH A;  1UL7 A;  1V5S A;  4EAI A;  2YA3 A;  2V8Q A;  2EHB D;  2Y8L A;  2QRC A;  2QR1 A;  4EAJ A;  4EAL A;  3OSE A;  2V9J A;  3TE5 A;  4CFF A;  2ZFD B;  2Y8Q A;  2QRD A;  4EAG A;  2QRE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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