2VOAA

Structure of an ap endonuclease from archaeoglobus fulgidus
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
257
structure length
256
Chain Sequence
MLKIATFNVNSIRSRLHIVIPWLKENKPDILCMQETKVENRKFPEADFHRIGYHVVFSGSKGRNGVAIASLEEPEDVSFGLDSEPKDEDRLIRAKIAGIDVINTYVPQGFKIDSEKYQYKLQWLERLYHYLQKTVDFRSFAVWCGDMNVAPEPIDVHSPDKLKNHVFHEDARRAYKKILELGFVDVLRKIHPNERIYTFYDYRVKGAIERGLGWRGDAILATPPLAERCVDCYADIKPRLAEKPSDHLPLVAVFDV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and Function of the Abasic Site Specificity Pocket of an Ap Endonuclease from Archaeoglobus Fulgidus.
pubmed doi rcsb
molecule tags Lyase
source organism Archaeoglobus fulgidus
molecule keywords EXODEOXYRIBONUCLEASE III
total genus 85
structure length 256
sequence length 257
chains with identical sequence B
ec nomenclature ec 4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
pdb deposition date 2008-02-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 2voaA00
5DFJA 3G0RA 1DEWA 3G8VA 1DNKA 4L1YA 5J8NA 5DFHA 4F1HB 3G38A 3DNIA 3U8UA 3MTCA 3L1WA 5DV2A 3GA6A 2JC4A 4GEWA 5INKA 3G4TA 2D1KB 4CMLA 2A42B 3W2XA 5DG0A 2XSWA 4FPVA 4F1RA 4F1HA 1I9ZA 5INOA 1WDUA 4B5HA 4QHDA 4L1ZA 2DDTA 3I41A 5J3SA 2O3CA 4GYZA 2ISIA 3G91A 3NR8A 4K6LF 2F1NA 4QHEA 4B5IA 5DFIA 4L21A 1E9NA 3TEBA 5DFFA 3K55A 1BIXA 2UYRX 2DDSA 1ATND 3I5VA 3G3YA 4L20A 2A40B 5A7JA 2EI9A 4B5JA 1HD7A 4JG3A 5J3PA 3N9VA 1AKOA 5INNA 3NGOA 4GZ1A 5J42A 3G0AA 3W3DB 5A7IA 4AWNA 3G2DA 5DV4A 3CJCD 2IMQX 1ZWXA 2JC5A 1NTFA 1SI6X 2DDRA 4GZ0A 4FVAA 5J3ZA 5INMA 2VOAA 1DE9A 3G3CA 3I48A 2A41B 4RUWA 1I9YA 2V0SA 5INLA 5INPA 2A3ZB 3G00A 4C1RA 4F1IA 5EWTA 3W2YA 1VYBA 1Y21A 3WCXA 2J63A 4B5FA 1DE8A 3G1KA 3NGQA 4B5MA 5INQA 4IEMA 4LNDA 5HT2A 4QH9A 1YJHA 4PUQA 4CMNA 4B5GA 2F2FB 3G2CA 3G6SA 4GZ2A 3MPRA 3NGNA 2DNJA 2O3HA 1SR4B 4A9CA 3I46A 3FZIA 5CFGA 5CFEA 2V0RA
chains in the Genus database with same CATH superfamily
5DFJA 3G0RA 1DEWA 3G8VA 1DNKA 4L1YA 5J8NA 5DFHA 4F1HB 3G38A 3DNIA 3U8UA 3MTCA 3L1WA 5DV2A 3GA6A 2JC4A 4GEWA 5INKA 3G4TA 2D1KB 4CMLA 2A42B 3W2XA 5DG0A 2XSWA 4FPVA 4F1RA 4F1HA 1I9ZA 5INOA 1WDUA 4B5HA 4QHDA 4L1ZA 2DDTA 3I41A 5J3SA 2O3CA 4GYZA 2ISIA 3G91A 3NR8A 4K6LF 2F1NA 4QHEA 4B5IA 5DFIA 4L21A 1E9NA 3TEBA 5DFFA 3K55A 1BIXA 2UYRX 2DDSA 1ATND 3I5VA 3G3YA 4L20A 2A40B 5A7JA 2EI9A 4B5JA 1HD7A 4JG3A 5J3PA 3N9VA 1AKOA 5INNA 3NGOA 4GZ1A 5J42A 3G0AA 3W3DB 5A7IA 4AWNA 3G2DA 5DV4A 3CJCD 2IMQX 1ZWXA 2JC5A 1NTFA 1SI6X 2DDRA 4GZ0A 4FVAA 5J3ZA 5INMA 2VOAA 1DE9A 3G3CA 3I48A 2A41B 4RUWA 1I9YA 2V0SA 5INLA 5INPA 2A3ZB 3G00A 4C1RA 4F1IA 5EWTA 3W2YA 1VYBA 1Y21A 3WCXA 2J63A 4B5FA 1DE8A 3G1KA 3NGQA 4B5MA 5INQA 4IEMA 4LNDA 5HT2A 4QH9A 1YJHA 4PUQA 4CMNA 4B5GA 2F2FB 3G2CA 3G6SA 4GZ2A 3MPRA 3NGNA 2DNJA 2O3HA 1SR4B 4A9CA 3I46A 3FZIA 5CFGA 5CFEA 2V0RA
chains in the Genus database with same CATH topology
5DFJA 3G0RA 1DEWA 3G8VA 1DNKA 4L1YA 5J8NA 5DFHA 4F1HB 3G38A 3DNIA 3U8UA 3MTCA 3L1WA 5DV2A 3GA6A 2JC4A 4GEWA 5INKA 3G4TA 2D1KB 4CMLA 2A42B 3W2XA 5DG0A 2XSWA 4FPVA 4F1RA 4F1HA 1I9ZA 5INOA 1WDUA 4B5HA 4QHDA 4L1ZA 2DDTA 3I41A 5J3SA 2O3CA 4GYZA 2ISIA 3G91A 3NR8A 4K6LF 2F1NA 4QHEA 4B5IA 5DFIA 4L21A 1E9NA 3TEBA 5DFFA 3K55A 1BIXA 2UYRX 2DDSA 1ATND 3I5VA 3G3YA 4L20A 2A40B 5A7JA 2EI9A 4B5JA 1HD7A 4JG3A 5J3PA 3N9VA 1AKOA 5INNA 3NGOA 4GZ1A 5J42A 3G0AA 3W3DB 5A7IA 4AWNA 3G2DA 5DV4A 3CJCD 2IMQX 1ZWXA 2JC5A 1NTFA 1SI6X 2DDRA 4GZ0A 4FVAA 5J3ZA 5INMA 2VOAA 1DE9A 3G3CA 3I48A 2A41B 4RUWA 1I9YA 2V0SA 5INLA 5INPA 2A3ZB 3G00A 4C1RA 4F1IA 5EWTA 3W2YA 1VYBA 1Y21A 3WCXA 2J63A 4B5FA 1DE8A 3G1KA 3NGQA 4B5MA 5INQA 4IEMA 4LNDA 5HT2A 4QH9A 1YJHA 4PUQA 4CMNA 4B5GA 2F2FB 3G2CA 3G6SA 4GZ2A 3MPRA 3NGNA 2DNJA 2O3HA 1SR4B 4A9CA 3I46A 3FZIA 5CFGA 5CFEA 2V0RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DFJ A;  3G0R A;  1DEW A;  3G8V A;  1DNK A;  4L1Y A;  5J8N A;  5DFH A;  4F1H B;  3G38 A;  3DNI A;  3U8U A;  3MTC A;  3L1W A;  5DV2 A;  3GA6 A;  2JC4 A;  4GEW A;  5INK A;  3G4T A;  2D1K B;  4CML A;  2A42 B;  3W2X A;  5DG0 A;  2XSW A;  4FPV A;  4F1R A;  4F1H A;  1I9Z A;  5INO A;  1WDU A;  4B5H A;  4QHD A;  4L1Z A;  2DDT A;  3I41 A;  5J3S A;  2O3C A;  4GYZ A;  2ISI A;  3G91 A;  3NR8 A;  4K6L F;  2F1N A;  4QHE A;  4B5I A;  5DFI A;  4L21 A;  1E9N A;  3TEB A;  5DFF A;  3K55 A;  1BIX A;  2UYR X;  2DDS A;  1ATN D;  3I5V A;  3G3Y A;  4L20 A;  2A40 B;  5A7J A;  2EI9 A;  4B5J A;  1HD7 A;  4JG3 A;  5J3P A;  3N9V A;  1AKO A;  5INN A;  3NGO A;  4GZ1 A;  5J42 A;  3G0A A;  3W3D B;  5A7I A;  4AWN A;  3G2D A;  5DV4 A;  3CJC D;  2IMQ X;  1ZWX A;  2JC5 A;  1NTF A;  1SI6 X;  2DDR A;  4GZ0 A;  4FVA A;  5J3Z A;  5INM A;  2VOA A;  1DE9 A;  3G3C A;  3I48 A;  2A41 B;  4RUW A;  1I9Y A;  2V0S A;  5INL A;  5INP A;  2A3Z B;  3G00 A;  4C1R A;  4F1I A;  5EWT A;  3W2Y A;  1VYB A;  1Y21 A;  3WCX A;  2J63 A;  4B5F A;  1DE8 A;  3G1K A;  3NGQ A;  4B5M A;  5INQ A;  4IEM A;  4LND A;  5HT2 A;  4QH9 A;  1YJH A;  4PUQ A;  4CMN A;  4B5G A;  2F2F B;  3G2C A;  3G6S A;  4GZ2 A;  3MPR A;  3NGN A;  2DNJ A;  2O3H A;  1SR4 B;  4A9C A;  3I46 A;  3FZI A;  5CFG A;  5CFE A;  2V0R A; 
#chains in the Genus database with same CATH topology
 5DFJ A;  3G0R A;  1DEW A;  3G8V A;  1DNK A;  4L1Y A;  5J8N A;  5DFH A;  4F1H B;  3G38 A;  3DNI A;  3U8U A;  3MTC A;  3L1W A;  5DV2 A;  3GA6 A;  2JC4 A;  4GEW A;  5INK A;  3G4T A;  2D1K B;  4CML A;  2A42 B;  3W2X A;  5DG0 A;  2XSW A;  4FPV A;  4F1R A;  4F1H A;  1I9Z A;  5INO A;  1WDU A;  4B5H A;  4QHD A;  4L1Z A;  2DDT A;  3I41 A;  5J3S A;  2O3C A;  4GYZ A;  2ISI A;  3G91 A;  3NR8 A;  4K6L F;  2F1N A;  4QHE A;  4B5I A;  5DFI A;  4L21 A;  1E9N A;  3TEB A;  5DFF A;  3K55 A;  1BIX A;  2UYR X;  2DDS A;  1ATN D;  3I5V A;  3G3Y A;  4L20 A;  2A40 B;  5A7J A;  2EI9 A;  4B5J A;  1HD7 A;  4JG3 A;  5J3P A;  3N9V A;  1AKO A;  5INN A;  3NGO A;  4GZ1 A;  5J42 A;  3G0A A;  3W3D B;  5A7I A;  4AWN A;  3G2D A;  5DV4 A;  3CJC D;  2IMQ X;  1ZWX A;  2JC5 A;  1NTF A;  1SI6 X;  2DDR A;  4GZ0 A;  4FVA A;  5J3Z A;  5INM A;  2VOA A;  1DE9 A;  3G3C A;  3I48 A;  2A41 B;  4RUW A;  1I9Y A;  2V0S A;  5INL A;  5INP A;  2A3Z B;  3G00 A;  4C1R A;  4F1I A;  5EWT A;  3W2Y A;  1VYB A;  1Y21 A;  3WCX A;  2J63 A;  4B5F A;  1DE8 A;  3G1K A;  3NGQ A;  4B5M A;  5INQ A;  4IEM A;  4LND A;  5HT2 A;  4QH9 A;  1YJH A;  4PUQ A;  4CMN A;  4B5G A;  2F2F B;  3G2C A;  3G6S A;  4GZ2 A;  3MPR A;  3NGN A;  2DNJ A;  2O3H A;  1SR4 B;  4A9C A;  3I46 A;  3FZI A;  5CFG A;  5CFE A;  2V0R A; 
#chains in the Genus database with same CATH homology
 5DFJ A;  3G0R A;  1DEW A;  3G8V A;  1DNK A;  4L1Y A;  5J8N A;  5DFH A;  4F1H B;  3G38 A;  3DNI A;  3U8U A;  3MTC A;  3L1W A;  5DV2 A;  3GA6 A;  2JC4 A;  4GEW A;  5INK A;  3G4T A;  2D1K B;  4CML A;  2A42 B;  3W2X A;  5DG0 A;  2XSW A;  4FPV A;  4F1R A;  4F1H A;  1I9Z A;  5INO A;  1WDU A;  4B5H A;  4QHD A;  4L1Z A;  2DDT A;  3I41 A;  5J3S A;  2O3C A;  4GYZ A;  2ISI A;  3G91 A;  3NR8 A;  4K6L F;  2F1N A;  4QHE A;  4B5I A;  5DFI A;  4L21 A;  1E9N A;  3TEB A;  5DFF A;  3K55 A;  1BIX A;  2UYR X;  2DDS A;  1ATN D;  3I5V A;  3G3Y A;  4L20 A;  2A40 B;  5A7J A;  2EI9 A;  4B5J A;  1HD7 A;  4JG3 A;  5J3P A;  3N9V A;  1AKO A;  5INN A;  3NGO A;  4GZ1 A;  5J42 A;  3G0A A;  3W3D B;  5A7I A;  4AWN A;  3G2D A;  5DV4 A;  3CJC D;  2IMQ X;  1ZWX A;  2JC5 A;  1NTF A;  1SI6 X;  2DDR A;  4GZ0 A;  4FVA A;  5J3Z A;  5INM A;  2VOA A;  1DE9 A;  3G3C A;  3I48 A;  2A41 B;  4RUW A;  1I9Y A;  2V0S A;  5INL A;  5INP A;  2A3Z B;  3G00 A;  4C1R A;  4F1I A;  5EWT A;  3W2Y A;  1VYB A;  1Y21 A;  3WCX A;  2J63 A;  4B5F A;  1DE8 A;  3G1K A;  3NGQ A;  4B5M A;  5INQ A;  4IEM A;  4LND A;  5HT2 A;  4QH9 A;  1YJH A;  4PUQ A;  4CMN A;  4B5G A;  2F2F B;  3G2C A;  3G6S A;  4GZ2 A;  3MPR A;  3NGN A;  2DNJ A;  2O3H A;  1SR4 B;  4A9C A;  3I46 A;  3FZI A;  5CFG A;  5CFE A;  2V0R A; 
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similar chains in the Genus database (?% sequence similarity)
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