2VUMC

Alpha-amanitin inhibited complete rna polymerase ii elongation complex
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
266
structure length
266
Chain Sequence
EEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of Transcription Inhibition by Alpha-Amanitin and Implications for RNA Polymerase II Translocation.
pubmed doi rcsb
molecule tags Transferase
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 46
structure length 266
sequence length 266
ec nomenclature
pdb deposition date 2008-05-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
C PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 2vumC02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 2vumC01
4A3JK 4Y52K 4C3JK 5C4XC 3S1RC 4A3FC 4OINA 3S16C 4Y7NK 5IP9K 3HOWC 2JA6K 1BDFA 4C3JC 4LJZA 1WCMC 3PO2K 3HOUK 4ZH4A 1I6VA 4A3FK 3GTKK 1YNNA 1I50K 3I4NK 4MQ9A 3CQZC 2JA6C 2A69A 5TMFA 4G7ZA 2CW0A 3H3VD 1WCMK 3DXJA 5IP7K 3HOUC 3I4NC 1Y1WK 3GTJK 2R92C 3GTGK 3FKIK 3HOYK 4A93C 4Y52C 4QJVA 2WAQL 5C4XK 4LK0A 3S1RK 4A3IC 2R92K 4Q4ZA 5IYDK 3HKZD 3FKIC 3HOYC 4AYBL 5IYBC 1XPPA 3PO2C 3H3VL 2JA8C 2JA7C 4QIWD 4XLPA 3GTKC 3HKZL 4A3IK 1I50C 1TWHC 2Y0SD 5IYDC 5M5XK 3CQZK 1Y1WC 1R9TC 3S1MK 3HOZC 2JA7K 3I4MC 2JA8K 3PO3K 3K7AC 1TWAC 3GTJC 3GTGC 4A93K 3S1MC 1R9TK 2NVQC 4GZYA 3HOZK 1SFOK 3K7AK 3S2HK 1TWAK 2Y0SL 3M3YK 5IYBK 2NVQK 2WB1D 1SFOC 2JA5C 4C2MC 2B63K 3S17K 1I6HK 4YFNA 1TWHK 5IYCC 5FJ8K 3GTOC 3M3YC 4JK1A 2R93C 4X6AC 4A3KK 3PO3C 3GTLK 3I4MK 4C2MK 2PPBA 4A3EC 5IYCK 5M5WK 3GTOK 2R93K 5FLMK 4X6AK 4A3KC 3GTLC 3RZOK 4XSXA 4G7HA 3S2HC 3GTMC 5M3MK 3GTQK 2PMZD 4BY1K 4KN4A 4G7OA 3RZOC 2B63C 2NVXC 1SMYA 3M4OC 5C3EC 1I6HC 2PMZL 2JA5K 3GTQC 2O5JA 4OIQA 5C44K 4BXXC 4A3BK 3S1QC 4A3MK 2YU9C 4KN7A 3S2DK 2NVXK 5C3EK 1TWGK 4A3BC 4YG2A 4A3EK 4QIWL 3HOXK 4A3MC 1TWFC 4YFKA 5FLMC 3H0GK 3S1QK 1HQMA 3S1NK 3GTMK 2NVYC 1TWGC 5C4JC 4XSZA 1Y1VC 3HOXC 4XLNA 4BY1C 3H0GC 1IW7A 2WAQD 3S14K 4QJVB 4LLGA 3S1NC 2NVTC 3S15K 3M4OK 5C44C 4BXXK 1Y1VK 4OIPA 3S2DC 2YU9K 3S14C 4AYBD 1I3QC 2NVTK 4A3CK 3EQLA 2BE5A 1TWFK 3RZDC 1I3QK 2E2JK 4OIOA 2NVYK 4A3CC 5C4JK 1TWCK 4C3IK 2VUMK 2E2IK 3S15C 2A6HA 4MEXA 2E2JC 4Q5SA 4OIRA 2E2HC 3HOVC 2R7ZK 1K83K 3WODA 2E2IC 2A68A 2PA8L 3GTPK 2O5IA 4A3LK 5D4DA 3HOWK 4BBSK 4MEYA 4C3HC 1K83C 4A3GC 3RZDK 5TMCA 5M5YK 1ZYRA 4A3LC 4A3DK 4LK1A 1TWCC 4C3IC 3S16K 2VUMC 4Y7NC 4BBRK 5IP9C 4A3DC 2R7ZC 1YNJA 4KMUA 2E2HK 2A6EA 5M3FK 3S17C 3HOVK 4NOIA 4BY7K 4BBRC 2WB1L 3GTPC 2PA8D 4A3JC 4BBSC 5IP7C 4YFXA 4C3HK 4BY7C 4A3GK
chains in the Genus database with same CATH superfamily
4FM9A 2E2HA 4A3JK 4C3JK 1XXAA 1O2AA 3S16C 1VRQC 2JA6K 1BDFA 3HOUK 1I6VA 1YNNA 3NUHA 2A69A 1IS1A 1WCMK 3DXJA 1ZBSA 4GFQA 4J3NA 5IP7K 1SFOA 1IQ0A 5TJ3A 4A93C 1Y1VA 3T00A 3S1RK 2P8TA 5JVHS 4Q4ZA 3H3VL 5DM6S 3HKZL 5IOSA 4XLPA 3GTKC 1L0WA 3SZYA 1I50A 1EFWA 4GTDA 1WIHA 2JA7K 3OPFA 1R9TA 3PO3K 2GAHC 1PJ5A 3V4GA 3CQZA 2Y0SL 3CF5S 1TWFA 3N0CA 2WB1D 1SFOC 2B63K 4C2MC 1I6HK 1ZQ1C 4JK1A 4KASA 3GTLK 3S0XA 2PPBA 4G7HA 2ZUEA 1FEUA 3SZZA 4G7OA 2PMZL 1DD5A 2ZFZA 3GTQC 5C44K 4KN7A 2NVXK 5C3EK 4A3EK 5L46A 1TWFC 4KAWX 1HQMA 4WILA 4AH6A 3S1NK 2NVYC 5C4JC 1G51A 2KQ1A 4C45A 2WAQD 4QJVB 4LLGA 2NVTC 4WCES 3AQOA 4OIPA 4M1XA 1F7UA 1GE9A 3S14C 2VUMA 1I3QC 4A3CK 2V6UA 2E2JK 2NVYK 4A3CC 4G0VA 1B4BA 2VUMK 2P5MA 4GTBA 1VH2A 1ISEA 1INNA 1K83C 1O29A 1UV7A 1TWCC 4C3IC 4KMHA 2PHCB 1WOPA 1YNJA 4KMUA 3VA7A 2A6EA 4KATA 3HOVK 4NOIA 3GTPC 1BGWA 4KB2A 2RH6A 1BS2A 4Y52K 1C0AA 4KMDA 1B4AA 5DM7S 1J6WA 1XZQB 4KB4A 4KC6A 2JA6C 5TMFA 3T02A 4FZBA 3GTJK 2R92C 3ADAC 3FOEA 3GTGK 2R7ZA 1AB4A 4QJVA 3GEEA 5C4XK 4LK0A 1EQRA 3L4KA 2XCOA 1WQHA 5IYDK 2ZJRS 4LQYA 1XPPA 5IYBC 1EH1A 2JA8C 4QIWD 3LPXA 3AQPA 1I50C 1TWHC 1R9TC 2JA8K 1XXBA 2ZUFA 3QX3A 4A93K 1WSVA 3S1MC 3HOZK 4GTAA 4WJ4A 3OEPA 2JH3A 2NVQK 1VLOA 4YFNA 1PJ6A 5FJ8K 2R92A 4WJ3M 2R93C 4A3KK 3I4MK 2FQTA 3FKIA 4WF9S 4C2MK 1DCHA 3PIPS 5IYCK 5IOTA 5M5WK 4X6AK 2L3UA 3DLLS 3G4CA 5M3MK 2PMZD 4GTFA 2B63C 1I6HC 5C3EC 4A3BK 2NVXA 1KQ4A 4BXXC 3S1QC 4A3MK 2YU9C 3TTGA 3S2DK 4BLBA 3Q3QA 4YG2A 2RGRA 4YFKA 5FLMC 4DDQA 4KM8A 1TWGC 5JVGS 1Y1VC 3H0GC 1IW7A 4BKWA 3GTLA 4BXXK 1Y1VK 5E68A 2CFAA 2NVTK 1TWFK 5JFEA 1XZPB 1O2BA 4OIOA 2YU9A 2A6HA 2E2HC 3GTJA 3GTGA 3WODA 2PA8L 4A3LK 5D4DA 4MEYA 1YCLA 4A3GC 3H0GA 5M5YK 4P5AA 1ZYRA 4A3LC 4A3DK 2KPUA 2XCRB 4A3DC 1PJ7A 2GSOA 5IORA 3S17C 5M3FK 4BBRC 5IP7C 4YFXA 3GTQA 4C3HK 3S17K 5C4XC 3S1RC 4A3FC 4OINA 3TFJA 1WOOA 2KWAA 1J6VA 5HL7S 5IP9K 3HOWC 4LJZA 3PO2K 4ZH4A 3GTKK 1XZQA 4MQ9A 3CQZC 1Y1WK 2CW0A 3HOUC 1F93A 4RMFA 3FKIK 1J6XA 2R92K 3HOYC 1O25A 3PO2C 2JA7C 2EBBA 3G4AA 4A3IK 5IYDC 5M5XK 1Y1WC 3HOZC 3IPJA 3I4MC 1TWAC 1DCPA 4GZYA 4PAAA 3TFIA 1IL2A 1SFOK 3K7AK 1TWAK 4IOCS 3M3YK 1ZXOA 5HL8A 2JA5C 4ILDA 1TWHK 5IYCC 2R93A 1O27A 3GTOA 1V5VA 4A3KC 4XSXA 1F9NA 3S2HC 1J98A 3BUEA 3OREA 2Y3PA 4XCHA 3GEHA 4BY1K 1HI9A 2NVXC 4OIQA 4LR2A 3LAJA 3A8IA 1XXCA 4QIWL 3HOXK 3GTMK 1USMA 3JSTA 4BY1C 3S1NC 1K83A 3M4OK 1TWCA 3EQLA 3RZDC 4WFNS 1I3QK 1DCOA 1O26A 3L4JA 3FOFA 2E2IK 2XCQA 1IE0A 4GT9A 4MEXA 2E2JC 2R7ZK 4Q5SA 1K83K 4GTCA 2E2IC 2NVYA 2O5IA 1WCMA 4BBSK 3T01A 4C3HC 3GSIA 3RZDK 5TMCA 2JA6A 2R93K 2VUMC 5IP9C 2R7ZC 4BLAA 2E2HK 1USOA 2B63A 2PA8D 2D6FC 1RU0A 2O5JA 3ERED 3HXAA 1EI6A 1VJEA 1O2FB 5EGHA 4Y7NK 1BJTA 2E2IA 4P9SA 1WOSA 4C3JC 1WCMC 3I4NK 4A3FK 1WSRA 3GDZA 1I50K 2FQOA 3HOWK 4G7ZA 3H3VD 3A8JA 3I4NC 2GSUA 1IBAA 2L5NA 5CHPA 3HOYK 4Y52C 2WAQL 4A3IC 3MMLB 3BP8C 3HKZD 3FKIC 3LAPA 4AYBL 2CFAB 4KDDA 4IOAS 3GTMA 4O2DA 4G0WA 2Y0SD 3CQZK 1XZPA 2V6SA 3S1MK 4GTEA 3K7AC 2V6TA 3GTJC 3GTGC 3AD9C 1R9TK 2NVQC 1JVIA 1EK8A 3S2HK 2GSNA 1JQWA 3PIOS 5IYBK 3FHZA 3GTOC 3M3YC 1TWGA 4X6AC 3PO3C 1ZVUA 5HQHA 4A3EC 3GTOK 2ZJPS 2ZJQS 4WFAS 3GTLC 1O28A 1TWHA 1WORA 4WFBS 5FLMK 3RZOK 3GTMC 3N3YA 3GTQK 3GIRA 1F7VA 1X31C 4KN4A 3RZOC 2JA5K 3GTPA 1SMYA 3M4OC 3LYWA 3N0BA 5JVOA 4IO9S 1WQFA 1TWGK 4A3BC 5IOQA 3BP3A 2KXYA 4A3MC 4LOWA 3H0GK 3S1QK 4KMAA 1VGXA 1YX2A 3AH5A 4XSZA 4XLNA 3HOXC 3S14K 4GTLA 3S15K 5C44C 3GEIA 4P5BA 3S2DC 2YU9K 2JA7A 4AYBD 1JOEA 3A8KA 3AD7C 1I3QA 1Y1WA 2BE5A 1TWAA 5C4JK 1TWCK 4C3IK 3S15C 3TFHA 4OIRA 4U67S 3HOVC 1O24A 2A68A 3AD8C 3CAGA 3GTPK 2JA5A 4PABA 4KARA 4KM9A 1WQGA 2W7VA 4LK1A 3S16K 4Y7NC 4BBRK 4G0UA 5EGEA 4BY7K 2WB1L 5CJ9A 4A3JC 2GAGC 4BBSC 3GTKA 4BY7C 4A3GK
chains in the Genus database with same CATH topology
4A3JK 4Y52K 4C3JK 5C4XC 3S1RC 4A3FC 4OINA 3S16C 4Y7NK 5IP9K 3HOWC 2JA6K 1BDFA 4C3JC 4LJZA 1WCMC 3PO2K 3HOUK 4ZH4A 1I6VA 4A3FK 3GTKK 1YNNA 1I50K 3I4NK 4MQ9A 3CQZC 2JA6C 2A69A 5TMFA 4G7ZA 2CW0A 3H3VD 1WCMK 3DXJA 5IP7K 3HOUC 3I4NC 1Y1WK 3GTJK 2R92C 3GTGK 3FKIK 3HOYK 4A93C 4Y52C 4QJVA 2WAQL 5C4XK 4LK0A 3S1RK 4A3IC 2R92K 4Q4ZA 5IYDK 3HKZD 3FKIC 3HOYC 4AYBL 5IYBC 1XPPA 3PO2C 3H3VL 2JA8C 2JA7C 4QIWD 4XLPA 3GTKC 3HKZL 4A3IK 1I50C 1TWHC 2Y0SD 5IYDC 5M5XK 3CQZK 1Y1WC 1R9TC 3S1MK 3HOZC 2JA7K 3I4MC 2JA8K 3PO3K 3K7AC 1TWAC 3GTJC 3GTGC 4A93K 3S1MC 1R9TK 2NVQC 4GZYA 3HOZK 1SFOK 3K7AK 3S2HK 1TWAK 2Y0SL 3M3YK 5IYBK 2NVQK 2WB1D 1SFOC 2JA5C 4C2MC 2B63K 3S17K 1I6HK 4YFNA 1TWHK 5IYCC 5FJ8K 3GTOC 3M3YC 4JK1A 2R93C 4X6AC 4A3KK 3PO3C 3GTLK 3I4MK 4C2MK 2PPBA 4A3EC 5IYCK 5M5WK 3GTOK 2R93K 5FLMK 4X6AK 4A3KC 3GTLC 3RZOK 4XSXA 4G7HA 3S2HC 3GTMC 5M3MK 3GTQK 2PMZD 4BY1K 4KN4A 4G7OA 3RZOC 2B63C 2NVXC 1SMYA 3M4OC 5C3EC 1I6HC 2PMZL 2JA5K 3GTQC 2O5JA 4OIQA 5C44K 4BXXC 4A3BK 3S1QC 4A3MK 2YU9C 4KN7A 3S2DK 2NVXK 5C3EK 1TWGK 4A3BC 4YG2A 4A3EK 4QIWL 3HOXK 4A3MC 1TWFC 4YFKA 5FLMC 3H0GK 3S1QK 1HQMA 3S1NK 3GTMK 2NVYC 1TWGC 5C4JC 4XSZA 1Y1VC 3HOXC 4XLNA 4BY1C 3H0GC 1IW7A 2WAQD 3S14K 4QJVB 4LLGA 3S1NC 2NVTC 3S15K 3M4OK 5C44C 4BXXK 1Y1VK 4OIPA 3S2DC 2YU9K 3S14C 4AYBD 1I3QC 2NVTK 4A3CK 3EQLA 2BE5A 1TWFK 3RZDC 1I3QK 2E2JK 4OIOA 2NVYK 4A3CC 5C4JK 1TWCK 4C3IK 2VUMK 2E2IK 3S15C 2A6HA 4MEXA 2E2JC 4Q5SA 4OIRA 2E2HC 3HOVC 2R7ZK 1K83K 3WODA 2E2IC 2A68A 2PA8L 3GTPK 2O5IA 4A3LK 5D4DA 3HOWK 4BBSK 4MEYA 4C3HC 1K83C 4A3GC 3RZDK 5TMCA 5M5YK 1ZYRA 4A3LC 4A3DK 4LK1A 1TWCC 4C3IC 3S16K 2VUMC 4Y7NC 4BBRK 5IP9C 4A3DC 2R7ZC 1YNJA 4KMUA 2E2HK 2A6EA 5M3FK 3S17C 3HOVK 4NOIA 4BY7K 4BBRC 2WB1L 3GTPC 2PA8D 4A3JC 4BBSC 5IP7C 4YFXA 4C3HK 4BY7C 4A3GK
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3J K;  4Y52 K;  4C3J K;  5C4X C;  3S1R C;  4A3F C;  4OIN A;  3S16 C;  4Y7N K;  5IP9 K;  3HOW C;  2JA6 K;  1BDF A;  4C3J C;  4LJZ A;  1WCM C;  3PO2 K;  3HOU K;  4ZH4 A;  1I6V A;  4A3F K;  3GTK K;  1YNN A;  1I50 K;  3I4N K;  4MQ9 A;  3CQZ C;  2JA6 C;  2A69 A;  5TMF A;  4G7Z A;  2CW0 A;  3H3V D;  1WCM K;  3DXJ A;  5IP7 K;  3HOU C;  3I4N C;  1Y1W K;  3GTJ K;  2R92 C;  3GTG K;  3FKI K;  3HOY K;  4A93 C;  4Y52 C;  4QJV A;  2WAQ L;  5C4X K;  4LK0 A;  3S1R K;  4A3I C;  2R92 K;  4Q4Z A;  5IYD K;  3HKZ D;  3FKI C;  3HOY C;  4AYB L;  5IYB C;  1XPP A;  3PO2 C;  3H3V L;  2JA8 C;  2JA7 C;  4QIW D;  4XLP A;  3GTK C;  3HKZ L;  4A3I K;  1I50 C;  1TWH C;  2Y0S D;  5IYD C;  5M5X K;  3CQZ K;  1Y1W C;  1R9T C;  3S1M K;  3HOZ C;  2JA7 K;  3I4M C;  2JA8 K;  3PO3 K;  3K7A C;  1TWA C;  3GTJ C;  3GTG C;  4A93 K;  3S1M C;  1R9T K;  2NVQ C;  4GZY A;  3HOZ K;  1SFO K;  3K7A K;  3S2H K;  1TWA K;  2Y0S L;  3M3Y K;  5IYB K;  2NVQ K;  2WB1 D;  1SFO C;  2JA5 C;  4C2M C;  2B63 K;  3S17 K;  1I6H K;  4YFN A;  1TWH K;  5IYC C;  5FJ8 K;  3GTO C;  3M3Y C;  4JK1 A;  2R93 C;  4X6A C;  4A3K K;  3PO3 C;  3GTL K;  3I4M K;  4C2M K;  2PPB A;  4A3E C;  5IYC K;  5M5W K;  3GTO K;  2R93 K;  5FLM K;  4X6A K;  4A3K C;  3GTL C;  3RZO K;  4XSX A;  4G7H A;  3S2H C;  3GTM C;  5M3M K;  3GTQ K;  2PMZ D;  4BY1 K;  4KN4 A;  4G7O A;  3RZO C;  2B63 C;  2NVX C;  1SMY A;  3M4O C;  5C3E C;  1I6H C;  2PMZ L;  2JA5 K;  3GTQ C;  2O5J A;  4OIQ A;  5C44 K;  4BXX C;  4A3B K;  3S1Q C;  4A3M K;  2YU9 C;  4KN7 A;  3S2D K;  2NVX K;  5C3E K;  1TWG K;  4A3B C;  4YG2 A;  4A3E K;  4QIW L;  3HOX K;  4A3M C;  1TWF C;  4YFK A;  5FLM C;  3H0G K;  3S1Q K;  1HQM A;  3S1N K;  3GTM K;  2NVY C;  1TWG C;  5C4J C;  4XSZ A;  1Y1V C;  3HOX C;  4XLN A;  4BY1 C;  3H0G C;  1IW7 A;  2WAQ D;  3S14 K;  4QJV B;  4LLG A;  3S1N C;  2NVT C;  3S15 K;  3M4O K;  5C44 C;  4BXX K;  1Y1V K;  4OIP A;  3S2D C;  2YU9 K;  3S14 C;  4AYB D;  1I3Q C;  2NVT K;  4A3C K;  3EQL A;  2BE5 A;  1TWF K;  3RZD C;  1I3Q K;  2E2J K;  4OIO A;  2NVY K;  4A3C C;  5C4J K;  1TWC K;  4C3I K;  2VUM K;  2E2I K;  3S15 C;  2A6H A;  4MEX A;  2E2J C;  4Q5S A;  4OIR A;  2E2H C;  3HOV C;  2R7Z K;  1K83 K;  3WOD A;  2E2I C;  2A68 A;  2PA8 L;  3GTP K;  2O5I A;  4A3L K;  5D4D A;  3HOW K;  4BBS K;  4MEY A;  4C3H C;  1K83 C;  4A3G C;  3RZD K;  5TMC A;  5M5Y K;  1ZYR A;  4A3L C;  4A3D K;  4LK1 A;  1TWC C;  4C3I C;  3S16 K;  2VUM C;  4Y7N C;  4BBR K;  5IP9 C;  4A3D C;  2R7Z C;  1YNJ A;  4KMU A;  2E2H K;  2A6E A;  5M3F K;  3S17 C;  3HOV K;  4NOI A;  4BY7 K;  4BBR C;  2WB1 L;  3GTP C;  2PA8 D;  4A3J C;  4BBS C;  5IP7 C;  4YFX A;  4C3H K;  4BY7 C;  4A3G K; 
#chains in the Genus database with same CATH topology
 4FM9 A;  2E2H A;  4A3J K;  4C3J K;  1XXA A;  1O2A A;  3S16 C;  1VRQ C;  2JA6 K;  1BDF A;  3HOU K;  1I6V A;  1YNN A;  3NUH A;  2A69 A;  1IS1 A;  1WCM K;  3DXJ A;  1ZBS A;  4GFQ A;  4J3N A;  5IP7 K;  1SFO A;  1IQ0 A;  5TJ3 A;  4A93 C;  1Y1V A;  3T00 A;  3S1R K;  2P8T A;  5JVH S;  4Q4Z A;  3H3V L;  5DM6 S;  3HKZ L;  5IOS A;  4XLP A;  3GTK C;  1L0W A;  3SZY A;  1I50 A;  1EFW A;  4GTD A;  1WIH A;  2JA7 K;  3OPF A;  1R9T A;  3PO3 K;  2GAH C;  1PJ5 A;  3V4G A;  3CQZ A;  2Y0S L;  3CF5 S;  1TWF A;  3N0C A;  2WB1 D;  1SFO C;  2B63 K;  4C2M C;  1I6H K;  1ZQ1 C;  4JK1 A;  4KAS A;  3GTL K;  3S0X A;  2PPB A;  4G7H A;  2ZUE A;  1FEU A;  3SZZ A;  4G7O A;  2PMZ L;  1DD5 A;  2ZFZ A;  3GTQ C;  5C44 K;  4KN7 A;  2NVX K;  5C3E K;  4A3E K;  5L46 A;  1TWF C;  4KAW X;  1HQM A;  4WIL A;  4AH6 A;  3S1N K;  2NVY C;  5C4J C;  1G51 A;  2KQ1 A;  4C45 A;  2WAQ D;  4QJV B;  4LLG A;  2NVT C;  4WCE S;  3AQO A;  4OIP A;  4M1X A;  1F7U A;  1GE9 A;  3S14 C;  2VUM A;  1I3Q C;  4A3C K;  2V6U A;  2E2J K;  2NVY K;  4A3C C;  4G0V A;  1B4B A;  2VUM K;  2P5M A;  4GTB A;  1VH2 A;  1ISE A;  1INN A;  1K83 C;  1O29 A;  1UV7 A;  1TWC C;  4C3I C;  4KMH A;  2PHC B;  1WOP A;  1YNJ A;  4KMU A;  3VA7 A;  2A6E A;  4KAT A;  3HOV K;  4NOI A;  3GTP C;  1BGW A;  4KB2 A;  2RH6 A;  1BS2 A;  4Y52 K;  1C0A A;  4KMD A;  1B4A A;  5DM7 S;  1J6W A;  1XZQ B;  4KB4 A;  4KC6 A;  2JA6 C;  5TMF A;  3T02 A;  4FZB A;  3GTJ K;  2R92 C;  3ADA C;  3FOE A;  3GTG K;  2R7Z A;  1AB4 A;  4QJV A;  3GEE A;  5C4X K;  4LK0 A;  1EQR A;  3L4K A;  2XCO A;  1WQH A;  5IYD K;  2ZJR S;  4LQY A;  1XPP A;  5IYB C;  1EH1 A;  2JA8 C;  4QIW D;  3LPX A;  3AQP A;  1I50 C;  1TWH C;  1R9T C;  2JA8 K;  1XXB A;  2ZUF A;  3QX3 A;  4A93 K;  1WSV A;  3S1M C;  3HOZ K;  4GTA A;  4WJ4 A;  3OEP A;  2JH3 A;  2NVQ K;  1VLO A;  4YFN A;  1PJ6 A;  5FJ8 K;  2R92 A;  4WJ3 M;  2R93 C;  4A3K K;  3I4M K;  2FQT A;  3FKI A;  4WF9 S;  4C2M K;  1DCH A;  3PIP S;  5IYC K;  5IOT A;  5M5W K;  4X6A K;  2L3U A;  3DLL S;  3G4C A;  5M3M K;  2PMZ D;  4GTF A;  2B63 C;  1I6H C;  5C3E C;  4A3B K;  2NVX A;  1KQ4 A;  4BXX C;  3S1Q C;  4A3M K;  2YU9 C;  3TTG A;  3S2D K;  4BLB A;  3Q3Q A;  4YG2 A;  2RGR A;  4YFK A;  5FLM C;  4DDQ A;  4KM8 A;  1TWG C;  5JVG S;  1Y1V C;  3H0G C;  1IW7 A;  4BKW A;  3GTL A;  4BXX K;  1Y1V K;  5E68 A;  2CFA A;  2NVT K;  1TWF K;  5JFE A;  1XZP B;  1O2B A;  4OIO A;  2YU9 A;  2A6H A;  2E2H C;  3GTJ A;  3GTG A;  3WOD A;  2PA8 L;  4A3L K;  5D4D A;  4MEY A;  1YCL A;  4A3G C;  3H0G A;  5M5Y K;  4P5A A;  1ZYR A;  4A3L C;  4A3D K;  2KPU A;  2XCR B;  4A3D C;  1PJ7 A;  2GSO A;  5IOR A;  3S17 C;  5M3F K;  4BBR C;  5IP7 C;  4YFX A;  3GTQ A;  4C3H K;  3S17 K;  5C4X C;  3S1R C;  4A3F C;  4OIN A;  3TFJ A;  1WOO A;  2KWA A;  1J6V A;  5HL7 S;  5IP9 K;  3HOW C;  4LJZ A;  3PO2 K;  4ZH4 A;  3GTK K;  1XZQ A;  4MQ9 A;  3CQZ C;  1Y1W K;  2CW0 A;  3HOU C;  1F93 A;  4RMF A;  3FKI K;  1J6X A;  2R92 K;  3HOY C;  1O25 A;  3PO2 C;  2JA7 C;  2EBB A;  3G4A A;  4A3I K;  5IYD C;  5M5X K;  1Y1W C;  3HOZ C;  3IPJ A;  3I4M C;  1TWA C;  1DCP A;  4GZY A;  4PAA A;  3TFI A;  1IL2 A;  1SFO K;  3K7A K;  1TWA K;  4IOC S;  3M3Y K;  1ZXO A;  5HL8 A;  2JA5 C;  4ILD A;  1TWH K;  5IYC C;  2R93 A;  1O27 A;  3GTO A;  1V5V A;  4A3K C;  4XSX A;  1F9N A;  3S2H C;  1J98 A;  3BUE A;  3ORE A;  2Y3P A;  4XCH A;  3GEH A;  4BY1 K;  1HI9 A;  2NVX C;  4OIQ A;  4LR2 A;  3LAJ A;  3A8I A;  1XXC A;  4QIW L;  3HOX K;  3GTM K;  1USM A;  3JST A;  4BY1 C;  3S1N C;  1K83 A;  3M4O K;  1TWC A;  3EQL A;  3RZD C;  4WFN S;  1I3Q K;  1DCO A;  1O26 A;  3L4J A;  3FOF A;  2E2I K;  2XCQ A;  1IE0 A;  4GT9 A;  4MEX A;  2E2J C;  2R7Z K;  4Q5S A;  1K83 K;  4GTC A;  2E2I C;  2NVY A;  2O5I A;  1WCM A;  4BBS K;  3T01 A;  4C3H C;  3GSI A;  3RZD K;  5TMC A;  2JA6 A;  2R93 K;  2VUM C;  5IP9 C;  2R7Z C;  4BLA A;  2E2H K;  1USO A;  2B63 A;  2PA8 D;  2D6F C;  1RU0 A;  2O5J A;  3ERE D;  3HXA A;  1EI6 A;  1VJE A;  1O2F B;  5EGH A;  4Y7N K;  1BJT A;  2E2I A;  4P9S A;  1WOS A;  4C3J C;  1WCM C;  3I4N K;  4A3F K;  1WSR A;  3GDZ A;  1I50 K;  2FQO A;  3HOW K;  4G7Z A;  3H3V D;  3A8J A;  3I4N C;  2GSU A;  1IBA A;  2L5N A;  5CHP A;  3HOY K;  4Y52 C;  2WAQ L;  4A3I C;  3MML B;  3BP8 C;  3HKZ D;  3FKI C;  3LAP A;  4AYB L;  2CFA B;  4KDD A;  4IOA S;  3GTM A;  4O2D A;  4G0W A;  2Y0S D;  3CQZ K;  1XZP A;  2V6S A;  3S1M K;  4GTE A;  3K7A C;  2V6T A;  3GTJ C;  3GTG C;  3AD9 C;  1R9T K;  2NVQ C;  1JVI A;  1EK8 A;  3S2H K;  2GSN A;  1JQW A;  3PIO S;  5IYB K;  3FHZ A;  3GTO C;  3M3Y C;  1TWG A;  4X6A C;  3PO3 C;  1ZVU A;  5HQH A;  4A3E C;  3GTO K;  2ZJP S;  2ZJQ S;  4WFA S;  3GTL C;  1O28 A;  1TWH A;  1WOR A;  4WFB S;  5FLM K;  3RZO K;  3GTM C;  3N3Y A;  3GTQ K;  3GIR A;  1F7V A;  1X31 C;  4KN4 A;  3RZO C;  2JA5 K;  3GTP A;  1SMY A;  3M4O C;  3LYW A;  3N0B A;  5JVO A;  4IO9 S;  1WQF A;  1TWG K;  4A3B C;  5IOQ A;  3BP3 A;  2KXY A;  4A3M C;  4LOW A;  3H0G K;  3S1Q K;  4KMA A;  1VGX A;  1YX2 A;  3AH5 A;  4XSZ A;  4XLN A;  3HOX C;  3S14 K;  4GTL A;  3S15 K;  5C44 C;  3GEI A;  4P5B A;  3S2D C;  2YU9 K;  2JA7 A;  4AYB D;  1JOE A;  3A8K A;  3AD7 C;  1I3Q A;  1Y1W A;  2BE5 A;  1TWA A;  5C4J K;  1TWC K;  4C3I K;  3S15 C;  3TFH A;  4OIR A;  4U67 S;  3HOV C;  1O24 A;  2A68 A;  3AD8 C;  3CAG A;  3GTP K;  2JA5 A;  4PAB A;  4KAR A;  4KM9 A;  1WQG A;  2W7V A;  4LK1 A;  3S16 K;  4Y7N C;  4BBR K;  4G0U A;  5EGE A;  4BY7 K;  2WB1 L;  5CJ9 A;  4A3J C;  2GAG C;  4BBS C;  3GTK A;  4BY7 C;  4A3G K; 
#chains in the Genus database with same CATH homology
 4A3J K;  4Y52 K;  4C3J K;  5C4X C;  3S1R C;  4A3F C;  4OIN A;  3S16 C;  4Y7N K;  5IP9 K;  3HOW C;  2JA6 K;  1BDF A;  4C3J C;  4LJZ A;  1WCM C;  3PO2 K;  3HOU K;  4ZH4 A;  1I6V A;  4A3F K;  3GTK K;  1YNN A;  1I50 K;  3I4N K;  4MQ9 A;  3CQZ C;  2JA6 C;  2A69 A;  5TMF A;  4G7Z A;  2CW0 A;  3H3V D;  1WCM K;  3DXJ A;  5IP7 K;  3HOU C;  3I4N C;  1Y1W K;  3GTJ K;  2R92 C;  3GTG K;  3FKI K;  3HOY K;  4A93 C;  4Y52 C;  4QJV A;  2WAQ L;  5C4X K;  4LK0 A;  3S1R K;  4A3I C;  2R92 K;  4Q4Z A;  5IYD K;  3HKZ D;  3FKI C;  3HOY C;  4AYB L;  5IYB C;  1XPP A;  3PO2 C;  3H3V L;  2JA8 C;  2JA7 C;  4QIW D;  4XLP A;  3GTK C;  3HKZ L;  4A3I K;  1I50 C;  1TWH C;  2Y0S D;  5IYD C;  5M5X K;  3CQZ K;  1Y1W C;  1R9T C;  3S1M K;  3HOZ C;  2JA7 K;  3I4M C;  2JA8 K;  3PO3 K;  3K7A C;  1TWA C;  3GTJ C;  3GTG C;  4A93 K;  3S1M C;  1R9T K;  2NVQ C;  4GZY A;  3HOZ K;  1SFO K;  3K7A K;  3S2H K;  1TWA K;  2Y0S L;  3M3Y K;  5IYB K;  2NVQ K;  2WB1 D;  1SFO C;  2JA5 C;  4C2M C;  2B63 K;  3S17 K;  1I6H K;  4YFN A;  1TWH K;  5IYC C;  5FJ8 K;  3GTO C;  3M3Y C;  4JK1 A;  2R93 C;  4X6A C;  4A3K K;  3PO3 C;  3GTL K;  3I4M K;  4C2M K;  2PPB A;  4A3E C;  5IYC K;  5M5W K;  3GTO K;  2R93 K;  5FLM K;  4X6A K;  4A3K C;  3GTL C;  3RZO K;  4XSX A;  4G7H A;  3S2H C;  3GTM C;  5M3M K;  3GTQ K;  2PMZ D;  4BY1 K;  4KN4 A;  4G7O A;  3RZO C;  2B63 C;  2NVX C;  1SMY A;  3M4O C;  5C3E C;  1I6H C;  2PMZ L;  2JA5 K;  3GTQ C;  2O5J A;  4OIQ A;  5C44 K;  4BXX C;  4A3B K;  3S1Q C;  4A3M K;  2YU9 C;  4KN7 A;  3S2D K;  2NVX K;  5C3E K;  1TWG K;  4A3B C;  4YG2 A;  4A3E K;  4QIW L;  3HOX K;  4A3M C;  1TWF C;  4YFK A;  5FLM C;  3H0G K;  3S1Q K;  1HQM A;  3S1N K;  3GTM K;  2NVY C;  1TWG C;  5C4J C;  4XSZ A;  1Y1V C;  3HOX C;  4XLN A;  4BY1 C;  3H0G C;  1IW7 A;  2WAQ D;  3S14 K;  4QJV B;  4LLG A;  3S1N C;  2NVT C;  3S15 K;  3M4O K;  5C44 C;  4BXX K;  1Y1V K;  4OIP A;  3S2D C;  2YU9 K;  3S14 C;  4AYB D;  1I3Q C;  2NVT K;  4A3C K;  3EQL A;  2BE5 A;  1TWF K;  3RZD C;  1I3Q K;  2E2J K;  4OIO A;  2NVY K;  4A3C C;  5C4J K;  1TWC K;  4C3I K;  2VUM K;  2E2I K;  3S15 C;  2A6H A;  4MEX A;  2E2J C;  4Q5S A;  4OIR A;  2E2H C;  3HOV C;  2R7Z K;  1K83 K;  3WOD A;  2E2I C;  2A68 A;  2PA8 L;  3GTP K;  2O5I A;  4A3L K;  5D4D A;  3HOW K;  4BBS K;  4MEY A;  4C3H C;  1K83 C;  4A3G C;  3RZD K;  5TMC A;  5M5Y K;  1ZYR A;  4A3L C;  4A3D K;  4LK1 A;  1TWC C;  4C3I C;  3S16 K;  2VUM C;  4Y7N C;  4BBR K;  5IP9 C;  4A3D C;  2R7Z C;  1YNJ A;  4KMU A;  2E2H K;  2A6E A;  5M3F K;  3S17 C;  3HOV K;  4NOI A;  4BY7 K;  4BBR C;  2WB1 L;  3GTP C;  2PA8 D;  4A3J C;  4BBS C;  5IP7 C;  4YFX A;  4C3H K;  4BY7 C;  4A3G K; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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