2VVCK

Aminopyrrolidine factor xa inhibitor
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
53
structure length
53
Chain Sequence
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design of Novel Aminopyrrolidine Factor Xa Inhibitors from a Screening Hit.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords ACTIVATED FACTOR XA HEAVY CHAIN
total genus 12
structure length 53
sequence length 53
chains with identical sequence L
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2008-06-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
K PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2vvcK00
5F19A 1MQ5L 1HX2A 1DX5I 1F0RB 1UZPA 2P3UA 2P95L 4ZAEB 4D0EA 1DVAL 2J34B 1DIYA 5IKTA 1ATAA 2WPJE 3H5CB 1G1SA 4X8VL 4BTTA 1XDTR 1NFXB 3N8ZA 1SZBA 2Y38A 1KLIL 4NGAL 2UWLB 1IQEL 3POYA 1RFNB 2EI6B 5L2ZL 2H9EL 1CX2A 1GK5A 5COXA 2PHBB 4D0FA 3FBYA 3OLUA 5JW1A 5KIRA 2K2TA 4Y71B 1DDXA 2W2ME 3LN0A 5CKNA 1X7AL 3SOQA 1U8CB 1AUTL 3ELAL 1L3YA 3QH0A 2TGFA 1IQFL 3DEMA 4YT6L 1V3XB 1P0SL 1HJ7A 1TOZA 1Z6EL 1G2MB 2WG4B 4YZUB 1XKBA 1YO8A 3N8WB 2JKHL 1B9WA 2VJ3A 3HPTA 2BZ6L 4BXSA 2EI8B 4ISIL 2GD4A 2WYJB 1FFMA 1NFUB 2J4IB 2VWOL 2BO2A 2WPIE 1CQEA 3F6UL 4OTJA 3OLTA 4Y6DB 2PUQL 1EMOA 3N8WA 1IQLL 3GCXE 1YGCL 1F0SB 1NFWB 1WHEA 1CCVA 3TBDA 1HRFA 2W3IB 2P93L 4MMZB 2P3FN 1U67A 1EZQB 1UZKA 1LPGA 1F7EA 4LMFA 3SOBB 3SOVA 3BPSE 6COXA 1ZAQA 1XFEA 4JZFL 3ZYGA 4Y79B 2XBXL 5JB8E 1LMJA 4JYVL 4BXWA 3M36L 5EGMB 4XBMA 1PRHA 2Y7XB 5CISA 3MDLA 4Y76B 2UWOB 4AQTA 4C16A 1FE2A 1IQGL 1W7XL 3GISX 4RRXA 3F1SB 1EAIC 2BOXA 3SW2A 3KQEL 4BDWA 1G1TA 1IQIL 3PGHA 3ZYIB 1EPJA 1URKA 1WHFA 4Y7BB 2PR3B 3HO4A 1MQ6L 1UZJA 1CVWL 3TK6B 2P26A 2W86A 4X8TL 3HO5A 2KL7A 4A7IA 2D1JB 2WFXB 1CVUA 4RRZA 2K2SB 3LC5B 2KV4A 5CKMA 1HAEA 4RRYA 3MQEA 1HREA 4OTYA 1APOA 1N1IA 2VH0B 3TZIA 2MGPA 1EPHA 3U7UG 3Q7DA 2J94B 3U73A 3LN1A 1IVOC 3GCWE 2FLGA 3QCWA 3N8XA 4XL1A 4CUDA 2YGOA 2NPRA 2W3KB 3HS6A 4RUTA 1K37A 1KSNB 2F9BL 1KIGL 2EI7B 5F1AA 1TLEA 2W2PE 3NTGA 2M74A 2XC4L 3M37L 4RRWA 1I0UA 3RR3A 3TH3L 2J95B 2I9BA 2P16L 2WFTA 2WYGB 4JYUL 3ENSA 3KQCL 4Z0KB 5E8DA 5L2YL 2WPHE 1OB1C 3CFWA 1K36A 5JB9E 1IQJL 3V65B 1EQHA 1EBVA 4JZEL 2MGRA 1LPKA 2VVCK 4FM5A 2XBVL 3KCGL 3CENL 1G1QA 5JVYA 3FFGL 2BMGA 2BOKL 4E1GA 2J38B 4NG9L 2FLRL 1FSBA 4PH9A 3N8YB 1N7DA 1NZIA 2VWNL 1BF9A 3HS7A 1UZQA 2VVUL 4D90A 4M11A 4COXA 2VWLL 1O5DL 2WPME 3LTGD 3N8YA 4Z6AL 5JBAE 4TGFA 5JVZA 5KN5C 2FLBL 1IQML 2J2UB 2UWPB 4M10A 4CUFA 4O1ZA 1Z6CA 5JBCE 2Q1JB 1IQNL 1NFYB 3N8VA 1IGXA 2OYUP 1YUKB 1C5MF 2WG3C 1MOXC 2FZZL 1ATEA 3HS5A 3KRKA 1EPIA 1JBUL 4LORA 2G00L 3KQDL 5IKVA 4RS0A 2Y82B 2KB9A 2W2OE 2VH6B 2Y5GL 1ATDA 1PFXL 1HZ8A 1QFKL 4G1MB 3ZYJB 1PTHA 4MMXB 3HO3A 3KL6B 1F7MA 1HT5A 2W2QE 2XC5L 4ZH8B 5K0HB 2P28B 2Y81B 1IQHL 4O02B 1FAKL 3BT2A 1IOXA 1NQLB 4BTIA 2AYLA 1L5GB 1IJQA 1JV2B 2XC0L 3V64C 2Y5FL 5L30L 4CSYA 1HCGB 4X8SL 4NA9L 2Y80B 3C9AC 3NT1A 4JZDL 1A3PA 1Q4GA 4MMYB 2P3FL 1M1XB 5IKQA 3KK6A 2BQ6A 1LPZA 1CEJA 3LC3B 2CJIB 1YUFA 4ISHL 1APQA 2ADXA 1ATBA 4BTUA 1P9JA 4ZHAB 4XLWA 4CUEA 1NPEB 2BQWA 3NTBA 1IOEL 2Y5HL 1TPGA 1LQDA 2B7DL 4Y7AB 1WU1B 3NJPC 2P94L 2RA0L 1NT0A 2P3TA 3LAQA 2W26B 2WPKE 4Z0LA 3QMOA 1G2LB 4X8UL 3TGFA 1COUA 1FAXL 4YT7L 1G1RA 2BOUA 2RNLA 1J9CL 1PGEA 2XBYL 1IGZA 1KLOA 2BOHA 3EGFA 5CKQA 3CS7L 3Q3KB 4BDXA 2Y7ZB 2VWMK 3P5BL 1XKAL 4ZXYL 2XBWL 3LTFB 2BQ7A 2OYEP 1IP0A 1HT8A 3TK5B 2VVVL 3CA7A 3KQBL 3FCSB 1EPGA 1PXXA 2W2NE 1HAFA 2RHPA 1DQBA 1EGFA 2FD6A 3R05A 2I9AA 1JL9A 5IKRA 1FJSL 1ADXA 5I46L 1FF7A 2WPLE 1KLJL 2YGPA 5JBBE 1W8BL 3IJEB 3LIWB 1YUGA 5FDQA 3IITB 1IQKL 2MHPA 3K9XA 3ASIA 2DDUA 1EMNA 1EQGA 3BT1A 1CCFA 4ZXXL
chains in the Genus database with same CATH superfamily
5F19A 1MQ5L 1HX2A 1DX5I 1F0RB 1UZPA 2P3UA 2P95L 4ZAEB 4D0EA 1DVAL 2J34B 1DIYA 5IKTA 1ATAA 2WPJE 3H5CB 1G1SA 4X8VL 4BTTA 1XDTR 1NFXB 3N8ZA 2HOXA 1SZBA 2Y38A 1KLIL 4NGAL 2UWLB 1IQEL 3POYA 1RFNB 2EI6B 5L2ZL 2H9EL 1CX2A 1GK5A 2BT8A 5COXA 2PHBB 4D0FA 3FBYA 3OLUA 5JW1A 5KIRA 2K2TA 4Y71B 1DDXA 2W2ME 3LN0A 5CKNA 1X7AL 3SOQA 1U8CB 1AUTL 3ELAL 1L3YA 3QH0A 2TGFA 1IQFL 3DEMA 4YT6L 1V3XB 1P0SL 1HJ7A 1TOZA 1Z6EL 1G2MB 2WG4B 4YZUB 1XKBA 1YO8A 3N8WB 2JKHL 1B9WA 2VJ3A 4A94C 3HPTA 2BZ6L 4BXSA 2EI8B 4ISIL 2GD4A 2WYJB 1FFMA 1NFUB 2J4IB 2VWOL 2BO2A 2WPIE 1CQEA 3F6UL 4OTJA 3OLTA 4Y6DB 2PUQL 1EMOA 3N8WA 1IQLL 3GCXE 1YGCL 1F0SB 1NFWB 1WHEA 1CCVA 3TBDA 1HRFA 2W3IB 2P93L 4MMZB 2P3FN 1U67A 1EZQB 1UZKA 1LPGA 1F7EA 4LMFA 3SOBB 3SOVA 4GU3A 3BPSE 6COXA 1ZAQA 1XFEA 4JZFL 3ZYGA 4Y79B 2XBXL 5JB8E 1LMJA 4JYVL 4BXWA 3M36L 5EGMB 4XBMA 1PRHA 2Y7XB 5CISA 3MDLA 4Y76B 2UWOB 4AQTA 4C16A 1FE2A 1IQGL 1W7XL 3GISX 4RRXA 3F1SB 1EAIC 2BOXA 3SW2A 3KQEL 4BDWA 1G1TA 1IQIL 3PGHA 3ZYIB 1EPJA 1URKA 1WHFA 4Y7BB 2PR3B 3HO4A 1MQ6L 1UZJA 1CVWL 3TK6B 2KNIA 2P26A 2W86A 4X8TL 3HO5A 2KL7A 1QIUA 1LK9A 4A7IA 2D1JB 2WFXB 1CVUA 4RRZA 2K2SB 3LC5B 2KV4A 5CKMA 1HAEA 4RRYA 3MQEA 1HREA 4OTYA 1APOA 1N1IA 2VH0B 3TZIA 2MGPA 1EPHA 3U7UG 3Q7DA 2J94B 3U73A 3LN1A 1IVOC 3GCWE 2FLGA 3QCWA 3N8XA 4XL1A 4CUDA 2YGOA 2NPRA 2W3KB 3HS6A 4RUTA 2WZPP 1K37A 1KSNB 2F9BL 1KIGL 2EI7B 5F1AA 1TLEA 2W2PE 3NTGA 2M74A 2XC4L 3M37L 4RRWA 1I0UA 3RR3A 3TH3L 2J95B 2I9BA 2P16L 2WFTA 2WYGB 4JYUL 2JJLA 3ENSA 3KQCL 4Z0KB 5E8DA 5L2YL 2WPHE 1OB1C 3CFWA 1K36A 5JB9E 1IQJL 3V65B 1EQHA 1EBVA 4JZEL 2MGRA 1LPKA 2VVCK 4FM5A 2XBVL 3KCGL 3CENL 1G1QA 5JVYA 3FFGL 2BMGA 2BOKL 4E1GA 2J38B 4NG9L 2FLRL 1FSBA 4PH9A 3N8YB 1N7DA 1NZIA 2VWNL 1BF9A 3HS7A 1V1HA 1UZQA 2VVUL 1KKEA 4D90A 4M11A 4COXA 2VWLL 1O5DL 2WPME 3LTGD 3N8YA 4Z6AL 5JBAE 3S6XA 4TGFA 5JVZA 5KN5C 2FLBL 1IQML 2J2UB 2UWPB 4M10A 4CUFA 4O1ZA 1Z6CA 5JBCE 2Q1JB 1IQNL 1NFYB 3N8VA 1IGXA 2OYUP 1YUKB 1C5MF 2WG3C 1MOXC 2FZZL 1ATEA 3HS5A 3KRKA 1EPIA 1JBUL 4LORA 2G00L 3KQDL 5IKVA 4RS0A 2Y82B 2KB9A 2W2OE 2VH6B 2Y5GL 1ATDA 1PFXL 1HZ8A 4GU4A 1QFKL 4G1MB 3ZYJB 1PTHA 4MMXB 3HO3A 3KL6B 1F7MA 1HT5A 2W2QE 2XC5L 4ZH8B 5K0HB 2P28B 2Y81B 1IQHL 4O02B 1FAKL 3BT2A 1IOXA 1NQLB 4BTIA 2AYLA 1L5GB 1IJQA 1JV2B 2XC0L 3V64C 2Y5FL 5L30L 4CSYA 1HCGB 4X8SL 4NA9L 2Y80B 3C9AC 3NT1A 4JZDL 1A3PA 1Q4GA 4MMYB 2P3FL 1M1XB 2BT7A 5IKQA 3KK6A 2BQ6A 1LPZA 1CEJA 3LC3B 2CJIB 1YUFA 2HORA 4ISHL 1APQA 2ADXA 1ATBA 4BTUA 1P9JA 4ZHAB 4XLWA 4CUEA 1NPEB 2BQWA 3NTBA 1IOEL 2Y5HL 1TPGA 1LQDA 2B7DL 4Y7AB 1WU1B 3NJPC 2P94L 1LMMA 1NT0A 2P3TA 2RA0L 3LAQA 2W26B 2WPKE 4Z0LA 3QMOA 1G2LB 4X8UL 3TGFA 1COUA 1FAXL 4YT7L 1G1RA 2BOUA 2RNLA 1J9CL 1PGEA 2XBYL 1IGZA 1KLOA 2BOHA 3EGFA 5CKQA 3CS7L 3Q3KB 2H9EC 4BDXA 2Y7ZB 2VWMK 3P5BL 1XKAL 4ZXYL 2YGQA 2XBWL 3LTFB 2BQ7A 2OYEP 1IP0A 1HT8A 3TK5B 2VVVL 2VRSA 1V1IA 2BSFA 3CA7A 3KQBL 3FCSB 1EPGA 1PXXA 2W2NE 1HAFA 2RHPA 1DQBA 1EGFA 2FD6A 3R05A 2I9AA 1JL9A 5IKRA 1FJSL 1ADXA 5I46L 1FF7A 2WPLE 1KLJL 2YGPA 5JBBE 1W8BL 3IJEB 3LIWB 1YUGA 5FDQA 3IITB 1IQKL 2MHPA 3K9XA 3ASIA 2DDUA 1EMNA 1EQGA 3BT1A 1CCFA 4ZXXL
chains in the Genus database with same CATH topology
5F19A 1MQ5L 1HX2A 1DX5I 1F0RB 1UZPA 2P3UA 2P95L 4ZAEB 4D0EA 1DVAL 2J34B 1DIYA 5IKTA 1ATAA 2WPJE 3H5CB 1G1SA 4X8VL 4BTTA 1XDTR 1NFXB 3N8ZA 1SZBA 2Y38A 1KLIL 4NGAL 2UWLB 1IQEL 3POYA 1RFNB 2EI6B 5L2ZL 2H9EL 1CX2A 1GK5A 5COXA 2PHBB 4D0FA 3FBYA 3OLUA 5JW1A 5KIRA 2K2TA 4Y71B 1DDXA 2W2ME 3LN0A 5CKNA 1X7AL 3SOQA 1U8CB 1AUTL 3ELAL 1L3YA 3QH0A 2TGFA 1IQFL 3DEMA 4YT6L 1V3XB 1P0SL 1HJ7A 1TOZA 1Z6EL 1G2MB 2WG4B 4YZUB 1XKBA 1YO8A 3N8WB 2JKHL 1B9WA 2VJ3A 4A94C 3HPTA 2BZ6L 4BXSA 2EI8B 4ISIL 2GD4A 2WYJB 1FFMA 1NFUB 2J4IB 2VWOL 2BO2A 2WPIE 1CQEA 3F6UL 4OTJA 3OLTA 4Y6DB 2PUQL 1EMOA 3N8WA 1IQLL 3GCXE 1YGCL 1F0SB 1NFWB 1WHEA 1CCVA 3TBDA 1HRFA 2W3IB 2P93L 4MMZB 2P3FN 1U67A 1EZQB 1UZKA 1LPGA 1F7EA 4LMFA 3SOBB 3SOVA 3BPSE 6COXA 1ZAQA 1XFEA 4JZFL 3ZYGA 4Y79B 2XBXL 5JB8E 1LMJA 4JYVL 4BXWA 3M36L 5EGMB 4XBMA 1PRHA 2Y7XB 5CISA 3MDLA 4Y76B 2UWOB 4AQTA 4C16A 1FE2A 1IQGL 1W7XL 3GISX 4RRXA 3F1SB 1EAIC 2BOXA 3SW2A 3KQEL 4BDWA 1G1TA 1IQIL 3PGHA 3ZYIB 1EPJA 1URKA 1WHFA 4Y7BB 2PR3B 3HO4A 1MQ6L 1UZJA 1CVWL 3TK6B 2KNIA 2P26A 2W86A 4X8TL 3HO5A 2KL7A 4A7IA 2D1JB 2WFXB 1CVUA 4RRZA 2K2SB 3LC5B 2KV4A 5CKMA 1HAEA 4RRYA 3MQEA 1HREA 4OTYA 1APOA 1N1IA 2VH0B 3TZIA 2MGPA 1EPHA 3U7UG 3Q7DA 2J94B 3U73A 3LN1A 1IVOC 3GCWE 2FLGA 3QCWA 3N8XA 4XL1A 4CUDA 2YGOA 2NPRA 2W3KB 3HS6A 4RUTA 2WZPP 1K37A 1KSNB 2F9BL 1KIGL 2EI7B 5F1AA 1TLEA 2W2PE 3NTGA 2M74A 2XC4L 3M37L 4RRWA 1I0UA 3RR3A 3TH3L 2J95B 2I9BA 2P16L 2WFTA 2WYGB 4JYUL 3ENSA 3KQCL 4Z0KB 5E8DA 5L2YL 2WPHE 1OB1C 3CFWA 1K36A 5JB9E 1IQJL 3V65B 1EQHA 1EBVA 4JZEL 2MGRA 1LPKA 2VVCK 4FM5A 2XBVL 3KCGL 3CENL 1G1QA 5JVYA 3FFGL 2BMGA 2BOKL 4E1GA 2J38B 4NG9L 2FLRL 1FSBA 4PH9A 3N8YB 1N7DA 1NZIA 2VWNL 1BF9A 3HS7A 1UZQA 2VVUL 4D90A 4M11A 4COXA 2VWLL 1O5DL 2WPME 3LTGD 3N8YA 4Z6AL 5JBAE 3S6XA 4TGFA 5JVZA 5KN5C 2FLBL 1IQML 2J2UB 2UWPB 4M10A 4CUFA 4O1ZA 1Z6CA 5JBCE 2Q1JB 1IQNL 1NFYB 3N8VA 1IGXA 2OYUP 1YUKB 1C5MF 2WG3C 1MOXC 2FZZL 1ATEA 3HS5A 3KRKA 1EPIA 1JBUL 4LORA 2G00L 3KQDL 5IKVA 4RS0A 2Y82B 2KB9A 2W2OE 2VH6B 2Y5GL 1ATDA 1PFXL 1HZ8A 1QFKL 4G1MB 3ZYJB 1PTHA 4MMXB 3HO3A 3KL6B 1F7MA 1HT5A 2W2QE 2XC5L 4ZH8B 5K0HB 2P28B 2Y81B 1IQHL 4O02B 1FAKL 3BT2A 1IOXA 1NQLB 4BTIA 2AYLA 1L5GB 1IJQA 1JV2B 2XC0L 3V64C 2Y5FL 5L30L 4CSYA 1HCGB 4X8SL 4NA9L 2Y80B 3C9AC 3NT1A 4JZDL 1A3PA 1Q4GA 4MMYB 2P3FL 1M1XB 5IKQA 3KK6A 2BQ6A 1LPZA 1CEJA 3LC3B 2CJIB 1YUFA 4ISHL 1APQA 2ADXA 1ATBA 4BTUA 1P9JA 4ZHAB 4XLWA 4CUEA 1NPEB 2BQWA 3NTBA 1IOEL 2Y5HL 1TPGA 1LQDA 2B7DL 4Y7AB 1WU1B 3NJPC 2P94L 1LMMA 1NT0A 2P3TA 2RA0L 3LAQA 2W26B 2WPKE 4Z0LA 3QMOA 1G2LB 4X8UL 3TGFA 1COUA 1FAXL 4YT7L 1G1RA 2BOUA 2RNLA 1J9CL 1PGEA 2XBYL 1IGZA 1KLOA 2BOHA 3EGFA 5CKQA 3CS7L 3Q3KB 2H9EC 4BDXA 2Y7ZB 2VWMK 3P5BL 1XKAL 4ZXYL 2YGQA 2XBWL 3LTFB 2BQ7A 2OYEP 1IP0A 1HT8A 3TK5B 2VVVL 3CA7A 3KQBL 3FCSB 1EPGA 1PXXA 2W2NE 1HAFA 2RHPA 1DQBA 1EGFA 2FD6A 3R05A 2I9AA 1JL9A 5IKRA 1FJSL 1ADXA 5I46L 1FF7A 2WPLE 1KLJL 2YGPA 5JBBE 1W8BL 3IJEB 3LIWB 1YUGA 5FDQA 3IITB 1IQKL 2MHPA 3K9XA 3ASIA 2DDUA 1EMNA 1EQGA 3BT1A 1CCFA 4ZXXL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5F19 A;  1MQ5 L;  1HX2 A;  1DX5 I;  1F0R B;  1UZP A;  2P3U A;  2P95 L;  4ZAE B;  4D0E A;  1DVA L;  2J34 B;  1DIY A;  5IKT A;  1ATA A;  2WPJ E;  3H5C B;  1G1S A;  4X8V L;  4BTT A;  1XDT R;  1NFX B;  3N8Z A;  1SZB A;  2Y38 A;  1KLI L;  4NGA L;  2UWL B;  1IQE L;  3POY A;  1RFN B;  2EI6 B;  5L2Z L;  2H9E L;  1CX2 A;  1GK5 A;  5COX A;  2PHB B;  4D0F A;  3FBY A;  3OLU A;  5JW1 A;  5KIR A;  2K2T A;  4Y71 B;  1DDX A;  2W2M E;  3LN0 A;  5CKN A;  1X7A L;  3SOQ A;  1U8C B;  1AUT L;  3ELA L;  1L3Y A;  3QH0 A;  2TGF A;  1IQF L;  3DEM A;  4YT6 L;  1V3X B;  1P0S L;  1HJ7 A;  1TOZ A;  1Z6E L;  1G2M B;  2WG4 B;  4YZU B;  1XKB A;  1YO8 A;  3N8W B;  2JKH L;  1B9W A;  2VJ3 A;  3HPT A;  2BZ6 L;  4BXS A;  2EI8 B;  4ISI L;  2GD4 A;  2WYJ B;  1FFM A;  1NFU B;  2J4I B;  2VWO L;  2BO2 A;  2WPI E;  1CQE A;  3F6U L;  4OTJ A;  3OLT A;  4Y6D B;  2PUQ L;  1EMO A;  3N8W A;  1IQL L;  3GCX E;  1YGC L;  1F0S B;  1NFW B;  1WHE A;  1CCV A;  3TBD A;  1HRF A;  2W3I B;  2P93 L;  4MMZ B;  2P3F N;  1U67 A;  1EZQ B;  1UZK A;  1LPG A;  1F7E A;  4LMF A;  3SOB B;  3SOV A;  3BPS E;  6COX A;  1ZAQ A;  1XFE A;  4JZF L;  3ZYG A;  4Y79 B;  2XBX L;  5JB8 E;  1LMJ A;  4JYV L;  4BXW A;  3M36 L;  5EGM B;  4XBM A;  1PRH A;  2Y7X B;  5CIS A;  3MDL A;  4Y76 B;  2UWO B;  4AQT A;  4C16 A;  1FE2 A;  1IQG L;  1W7X L;  3GIS X;  4RRX A;  3F1S B;  1EAI C;  2BOX A;  3SW2 A;  3KQE L;  4BDW A;  1G1T A;  1IQI L;  3PGH A;  3ZYI B;  1EPJ A;  1URK A;  1WHF A;  4Y7B B;  2PR3 B;  3HO4 A;  1MQ6 L;  1UZJ A;  1CVW L;  3TK6 B;  2P26 A;  2W86 A;  4X8T L;  3HO5 A;  2KL7 A;  4A7I A;  2D1J B;  2WFX B;  1CVU A;  4RRZ A;  2K2S B;  3LC5 B;  2KV4 A;  5CKM A;  1HAE A;  4RRY A;  3MQE A;  1HRE A;  4OTY A;  1APO A;  1N1I A;  2VH0 B;  3TZI A;  2MGP A;  1EPH A;  3U7U G;  3Q7D A;  2J94 B;  3U73 A;  3LN1 A;  1IVO C;  3GCW E;  2FLG A;  3QCW A;  3N8X A;  4XL1 A;  4CUD A;  2YGO A;  2NPR A;  2W3K B;  3HS6 A;  4RUT A;  1K37 A;  1KSN B;  2F9B L;  1KIG L;  2EI7 B;  5F1A A;  1TLE A;  2W2P E;  3NTG A;  2M74 A;  2XC4 L;  3M37 L;  4RRW A;  1I0U A;  3RR3 A;  3TH3 L;  2J95 B;  2I9B A;  2P16 L;  2WFT A;  2WYG B;  4JYU L;  3ENS A;  3KQC L;  4Z0K B;  5E8D A;  5L2Y L;  2WPH E;  1OB1 C;  3CFW A;  1K36 A;  5JB9 E;  1IQJ L;  3V65 B;  1EQH A;  1EBV A;  4JZE L;  2MGR A;  1LPK A;  2VVC K;  4FM5 A;  2XBV L;  3KCG L;  3CEN L;  1G1Q A;  5JVY A;  3FFG L;  2BMG A;  2BOK L;  4E1G A;  2J38 B;  4NG9 L;  2FLR L;  1FSB A;  4PH9 A;  3N8Y B;  1N7D A;  1NZI A;  2VWN L;  1BF9 A;  3HS7 A;  1UZQ A;  2VVU L;  4D90 A;  4M11 A;  4COX A;  2VWL L;  1O5D L;  2WPM E;  3LTG D;  3N8Y A;  4Z6A L;  5JBA E;  4TGF A;  5JVZ A;  5KN5 C;  2FLB L;  1IQM L;  2J2U B;  2UWP B;  4M10 A;  4CUF A;  4O1Z A;  1Z6C A;  5JBC E;  2Q1J B;  1IQN L;  1NFY B;  3N8V A;  1IGX A;  2OYU P;  1YUK B;  1C5M F;  2WG3 C;  1MOX C;  2FZZ L;  1ATE A;  3HS5 A;  3KRK A;  1EPI A;  1JBU L;  4LOR A;  2G00 L;  3KQD L;  5IKV A;  4RS0 A;  2Y82 B;  2KB9 A;  2W2O E;  2VH6 B;  2Y5G L;  1ATD A;  1PFX L;  1HZ8 A;  1QFK L;  4G1M B;  3ZYJ B;  1PTH A;  4MMX B;  3HO3 A;  3KL6 B;  1F7M A;  1HT5 A;  2W2Q E;  2XC5 L;  4ZH8 B;  5K0H B;  2P28 B;  2Y81 B;  1IQH L;  4O02 B;  1FAK L;  3BT2 A;  1IOX A;  1NQL B;  4BTI A;  2AYL A;  1L5G B;  1IJQ A;  1JV2 B;  2XC0 L;  3V64 C;  2Y5F L;  5L30 L;  4CSY A;  1HCG B;  4X8S L;  4NA9 L;  2Y80 B;  3C9A C;  3NT1 A;  4JZD L;  1A3P A;  1Q4G A;  4MMY B;  2P3F L;  1M1X B;  5IKQ A;  3KK6 A;  2BQ6 A;  1LPZ A;  1CEJ A;  3LC3 B;  2CJI B;  1YUF A;  4ISH L;  1APQ A;  2ADX A;  1ATB A;  4BTU A;  1P9J A;  4ZHA B;  4XLW A;  4CUE A;  1NPE B;  2BQW A;  3NTB A;  1IOE L;  2Y5H L;  1TPG A;  1LQD A;  2B7D L;  4Y7A B;  1WU1 B;  3NJP C;  2P94 L;  2RA0 L;  1NT0 A;  2P3T A;  3LAQ A;  2W26 B;  2WPK E;  4Z0L A;  3QMO A;  1G2L B;  4X8U L;  3TGF A;  1COU A;  1FAX L;  4YT7 L;  1G1R A;  2BOU A;  2RNL A;  1J9C L;  1PGE A;  2XBY L;  1IGZ A;  1KLO A;  2BOH A;  3EGF A;  5CKQ A;  3CS7 L;  3Q3K B;  4BDX A;  2Y7Z B;  2VWM K;  3P5B L;  1XKA L;  4ZXY L;  2XBW L;  3LTF B;  2BQ7 A;  2OYE P;  1IP0 A;  1HT8 A;  3TK5 B;  2VVV L;  3CA7 A;  3KQB L;  3FCS B;  1EPG A;  1PXX A;  2W2N E;  1HAF A;  2RHP A;  1DQB A;  1EGF A;  2FD6 A;  3R05 A;  2I9A A;  1JL9 A;  5IKR A;  1FJS L;  1ADX A;  5I46 L;  1FF7 A;  2WPL E;  1KLJ L;  2YGP A;  5JBB E;  1W8B L;  3IJE B;  3LIW B;  1YUG A;  5FDQ A;  3IIT B;  1IQK L;  2MHP A;  3K9X A;  3ASI A;  2DDU A;  1EMN A;  1EQG A;  3BT1 A;  1CCF A;  4ZXX L; 
#chains in the Genus database with same CATH topology
 5F19 A;  1MQ5 L;  1HX2 A;  1DX5 I;  1F0R B;  1UZP A;  2P3U A;  2P95 L;  4ZAE B;  4D0E A;  1DVA L;  2J34 B;  1DIY A;  5IKT A;  1ATA A;  2WPJ E;  3H5C B;  1G1S A;  4X8V L;  4BTT A;  1XDT R;  1NFX B;  3N8Z A;  2HOX A;  1SZB A;  2Y38 A;  1KLI L;  4NGA L;  2UWL B;  1IQE L;  3POY A;  1RFN B;  2EI6 B;  5L2Z L;  2H9E L;  1CX2 A;  1GK5 A;  2BT8 A;  5COX A;  2PHB B;  4D0F A;  3FBY A;  3OLU A;  5JW1 A;  5KIR A;  2K2T A;  4Y71 B;  1DDX A;  2W2M E;  3LN0 A;  5CKN A;  1X7A L;  3SOQ A;  1U8C B;  1AUT L;  3ELA L;  1L3Y A;  3QH0 A;  2TGF A;  1IQF L;  3DEM A;  4YT6 L;  1V3X B;  1P0S L;  1HJ7 A;  1TOZ A;  1Z6E L;  1G2M B;  2WG4 B;  4YZU B;  1XKB A;  1YO8 A;  3N8W B;  2JKH L;  1B9W A;  2VJ3 A;  4A94 C;  3HPT A;  2BZ6 L;  4BXS A;  2EI8 B;  4ISI L;  2GD4 A;  2WYJ B;  1FFM A;  1NFU B;  2J4I B;  2VWO L;  2BO2 A;  2WPI E;  1CQE A;  3F6U L;  4OTJ A;  3OLT A;  4Y6D B;  2PUQ L;  1EMO A;  3N8W A;  1IQL L;  3GCX E;  1YGC L;  1F0S B;  1NFW B;  1WHE A;  1CCV A;  3TBD A;  1HRF A;  2W3I B;  2P93 L;  4MMZ B;  2P3F N;  1U67 A;  1EZQ B;  1UZK A;  1LPG A;  1F7E A;  4LMF A;  3SOB B;  3SOV A;  4GU3 A;  3BPS E;  6COX A;  1ZAQ A;  1XFE A;  4JZF L;  3ZYG A;  4Y79 B;  2XBX L;  5JB8 E;  1LMJ A;  4JYV L;  4BXW A;  3M36 L;  5EGM B;  4XBM A;  1PRH A;  2Y7X B;  5CIS A;  3MDL A;  4Y76 B;  2UWO B;  4AQT A;  4C16 A;  1FE2 A;  1IQG L;  1W7X L;  3GIS X;  4RRX A;  3F1S B;  1EAI C;  2BOX A;  3SW2 A;  3KQE L;  4BDW A;  1G1T A;  1IQI L;  3PGH A;  3ZYI B;  1EPJ A;  1URK A;  1WHF A;  4Y7B B;  2PR3 B;  3HO4 A;  1MQ6 L;  1UZJ A;  1CVW L;  3TK6 B;  2KNI A;  2P26 A;  2W86 A;  4X8T L;  3HO5 A;  2KL7 A;  1QIU A;  1LK9 A;  4A7I A;  2D1J B;  2WFX B;  1CVU A;  4RRZ A;  2K2S B;  3LC5 B;  2KV4 A;  5CKM A;  1HAE A;  4RRY A;  3MQE A;  1HRE A;  4OTY A;  1APO A;  1N1I A;  2VH0 B;  3TZI A;  2MGP A;  1EPH A;  3U7U G;  3Q7D A;  2J94 B;  3U73 A;  3LN1 A;  1IVO C;  3GCW E;  2FLG A;  3QCW A;  3N8X A;  4XL1 A;  4CUD A;  2YGO A;  2NPR A;  2W3K B;  3HS6 A;  4RUT A;  2WZP P;  1K37 A;  1KSN B;  2F9B L;  1KIG L;  2EI7 B;  5F1A A;  1TLE A;  2W2P E;  3NTG A;  2M74 A;  2XC4 L;  3M37 L;  4RRW A;  1I0U A;  3RR3 A;  3TH3 L;  2J95 B;  2I9B A;  2P16 L;  2WFT A;  2WYG B;  4JYU L;  2JJL A;  3ENS A;  3KQC L;  4Z0K B;  5E8D A;  5L2Y L;  2WPH E;  1OB1 C;  3CFW A;  1K36 A;  5JB9 E;  1IQJ L;  3V65 B;  1EQH A;  1EBV A;  4JZE L;  2MGR A;  1LPK A;  2VVC K;  4FM5 A;  2XBV L;  3KCG L;  3CEN L;  1G1Q A;  5JVY A;  3FFG L;  2BMG A;  2BOK L;  4E1G A;  2J38 B;  4NG9 L;  2FLR L;  1FSB A;  4PH9 A;  3N8Y B;  1N7D A;  1NZI A;  2VWN L;  1BF9 A;  3HS7 A;  1V1H A;  1UZQ A;  2VVU L;  1KKE A;  4D90 A;  4M11 A;  4COX A;  2VWL L;  1O5D L;  2WPM E;  3LTG D;  3N8Y A;  4Z6A L;  5JBA E;  3S6X A;  4TGF A;  5JVZ A;  5KN5 C;  2FLB L;  1IQM L;  2J2U B;  2UWP B;  4M10 A;  4CUF A;  4O1Z A;  1Z6C A;  5JBC E;  2Q1J B;  1IQN L;  1NFY B;  3N8V A;  1IGX A;  2OYU P;  1YUK B;  1C5M F;  2WG3 C;  1MOX C;  2FZZ L;  1ATE A;  3HS5 A;  3KRK A;  1EPI A;  1JBU L;  4LOR A;  2G00 L;  3KQD L;  5IKV A;  4RS0 A;  2Y82 B;  2KB9 A;  2W2O E;  2VH6 B;  2Y5G L;  1ATD A;  1PFX L;  1HZ8 A;  4GU4 A;  1QFK L;  4G1M B;  3ZYJ B;  1PTH A;  4MMX B;  3HO3 A;  3KL6 B;  1F7M A;  1HT5 A;  2W2Q E;  2XC5 L;  4ZH8 B;  5K0H B;  2P28 B;  2Y81 B;  1IQH L;  4O02 B;  1FAK L;  3BT2 A;  1IOX A;  1NQL B;  4BTI A;  2AYL A;  1L5G B;  1IJQ A;  1JV2 B;  2XC0 L;  3V64 C;  2Y5F L;  5L30 L;  4CSY A;  1HCG B;  4X8S L;  4NA9 L;  2Y80 B;  3C9A C;  3NT1 A;  4JZD L;  1A3P A;  1Q4G A;  4MMY B;  2P3F L;  1M1X B;  2BT7 A;  5IKQ A;  3KK6 A;  2BQ6 A;  1LPZ A;  1CEJ A;  3LC3 B;  2CJI B;  1YUF A;  2HOR A;  4ISH L;  1APQ A;  2ADX A;  1ATB A;  4BTU A;  1P9J A;  4ZHA B;  4XLW A;  4CUE A;  1NPE B;  2BQW A;  3NTB A;  1IOE L;  2Y5H L;  1TPG A;  1LQD A;  2B7D L;  4Y7A B;  1WU1 B;  3NJP C;  2P94 L;  1LMM A;  1NT0 A;  2P3T A;  2RA0 L;  3LAQ A;  2W26 B;  2WPK E;  4Z0L A;  3QMO A;  1G2L B;  4X8U L;  3TGF A;  1COU A;  1FAX L;  4YT7 L;  1G1R A;  2BOU A;  2RNL A;  1J9C L;  1PGE A;  2XBY L;  1IGZ A;  1KLO A;  2BOH A;  3EGF A;  5CKQ A;  3CS7 L;  3Q3K B;  2H9E C;  4BDX A;  2Y7Z B;  2VWM K;  3P5B L;  1XKA L;  4ZXY L;  2YGQ A;  2XBW L;  3LTF B;  2BQ7 A;  2OYE P;  1IP0 A;  1HT8 A;  3TK5 B;  2VVV L;  2VRS A;  1V1I A;  2BSF A;  3CA7 A;  3KQB L;  3FCS B;  1EPG A;  1PXX A;  2W2N E;  1HAF A;  2RHP A;  1DQB A;  1EGF A;  2FD6 A;  3R05 A;  2I9A A;  1JL9 A;  5IKR A;  1FJS L;  1ADX A;  5I46 L;  1FF7 A;  2WPL E;  1KLJ L;  2YGP A;  5JBB E;  1W8B L;  3IJE B;  3LIW B;  1YUG A;  5FDQ A;  3IIT B;  1IQK L;  2MHP A;  3K9X A;  3ASI A;  2DDU A;  1EMN A;  1EQG A;  3BT1 A;  1CCF A;  4ZXX L; 
#chains in the Genus database with same CATH homology
 5F19 A;  1MQ5 L;  1HX2 A;  1DX5 I;  1F0R B;  1UZP A;  2P3U A;  2P95 L;  4ZAE B;  4D0E A;  1DVA L;  2J34 B;  1DIY A;  5IKT A;  1ATA A;  2WPJ E;  3H5C B;  1G1S A;  4X8V L;  4BTT A;  1XDT R;  1NFX B;  3N8Z A;  1SZB A;  2Y38 A;  1KLI L;  4NGA L;  2UWL B;  1IQE L;  3POY A;  1RFN B;  2EI6 B;  5L2Z L;  2H9E L;  1CX2 A;  1GK5 A;  5COX A;  2PHB B;  4D0F A;  3FBY A;  3OLU A;  5JW1 A;  5KIR A;  2K2T A;  4Y71 B;  1DDX A;  2W2M E;  3LN0 A;  5CKN A;  1X7A L;  3SOQ A;  1U8C B;  1AUT L;  3ELA L;  1L3Y A;  3QH0 A;  2TGF A;  1IQF L;  3DEM A;  4YT6 L;  1V3X B;  1P0S L;  1HJ7 A;  1TOZ A;  1Z6E L;  1G2M B;  2WG4 B;  4YZU B;  1XKB A;  1YO8 A;  3N8W B;  2JKH L;  1B9W A;  2VJ3 A;  4A94 C;  3HPT A;  2BZ6 L;  4BXS A;  2EI8 B;  4ISI L;  2GD4 A;  2WYJ B;  1FFM A;  1NFU B;  2J4I B;  2VWO L;  2BO2 A;  2WPI E;  1CQE A;  3F6U L;  4OTJ A;  3OLT A;  4Y6D B;  2PUQ L;  1EMO A;  3N8W A;  1IQL L;  3GCX E;  1YGC L;  1F0S B;  1NFW B;  1WHE A;  1CCV A;  3TBD A;  1HRF A;  2W3I B;  2P93 L;  4MMZ B;  2P3F N;  1U67 A;  1EZQ B;  1UZK A;  1LPG A;  1F7E A;  4LMF A;  3SOB B;  3SOV A;  3BPS E;  6COX A;  1ZAQ A;  1XFE A;  4JZF L;  3ZYG A;  4Y79 B;  2XBX L;  5JB8 E;  1LMJ A;  4JYV L;  4BXW A;  3M36 L;  5EGM B;  4XBM A;  1PRH A;  2Y7X B;  5CIS A;  3MDL A;  4Y76 B;  2UWO B;  4AQT A;  4C16 A;  1FE2 A;  1IQG L;  1W7X L;  3GIS X;  4RRX A;  3F1S B;  1EAI C;  2BOX A;  3SW2 A;  3KQE L;  4BDW A;  1G1T A;  1IQI L;  3PGH A;  3ZYI B;  1EPJ A;  1URK A;  1WHF A;  4Y7B B;  2PR3 B;  3HO4 A;  1MQ6 L;  1UZJ A;  1CVW L;  3TK6 B;  2KNI A;  2P26 A;  2W86 A;  4X8T L;  3HO5 A;  2KL7 A;  4A7I A;  2D1J B;  2WFX B;  1CVU A;  4RRZ A;  2K2S B;  3LC5 B;  2KV4 A;  5CKM A;  1HAE A;  4RRY A;  3MQE A;  1HRE A;  4OTY A;  1APO A;  1N1I A;  2VH0 B;  3TZI A;  2MGP A;  1EPH A;  3U7U G;  3Q7D A;  2J94 B;  3U73 A;  3LN1 A;  1IVO C;  3GCW E;  2FLG A;  3QCW A;  3N8X A;  4XL1 A;  4CUD A;  2YGO A;  2NPR A;  2W3K B;  3HS6 A;  4RUT A;  2WZP P;  1K37 A;  1KSN B;  2F9B L;  1KIG L;  2EI7 B;  5F1A A;  1TLE A;  2W2P E;  3NTG A;  2M74 A;  2XC4 L;  3M37 L;  4RRW A;  1I0U A;  3RR3 A;  3TH3 L;  2J95 B;  2I9B A;  2P16 L;  2WFT A;  2WYG B;  4JYU L;  3ENS A;  3KQC L;  4Z0K B;  5E8D A;  5L2Y L;  2WPH E;  1OB1 C;  3CFW A;  1K36 A;  5JB9 E;  1IQJ L;  3V65 B;  1EQH A;  1EBV A;  4JZE L;  2MGR A;  1LPK A;  2VVC K;  4FM5 A;  2XBV L;  3KCG L;  3CEN L;  1G1Q A;  5JVY A;  3FFG L;  2BMG A;  2BOK L;  4E1G A;  2J38 B;  4NG9 L;  2FLR L;  1FSB A;  4PH9 A;  3N8Y B;  1N7D A;  1NZI A;  2VWN L;  1BF9 A;  3HS7 A;  1UZQ A;  2VVU L;  4D90 A;  4M11 A;  4COX A;  2VWL L;  1O5D L;  2WPM E;  3LTG D;  3N8Y A;  4Z6A L;  5JBA E;  3S6X A;  4TGF A;  5JVZ A;  5KN5 C;  2FLB L;  1IQM L;  2J2U B;  2UWP B;  4M10 A;  4CUF A;  4O1Z A;  1Z6C A;  5JBC E;  2Q1J B;  1IQN L;  1NFY B;  3N8V A;  1IGX A;  2OYU P;  1YUK B;  1C5M F;  2WG3 C;  1MOX C;  2FZZ L;  1ATE A;  3HS5 A;  3KRK A;  1EPI A;  1JBU L;  4LOR A;  2G00 L;  3KQD L;  5IKV A;  4RS0 A;  2Y82 B;  2KB9 A;  2W2O E;  2VH6 B;  2Y5G L;  1ATD A;  1PFX L;  1HZ8 A;  1QFK L;  4G1M B;  3ZYJ B;  1PTH A;  4MMX B;  3HO3 A;  3KL6 B;  1F7M A;  1HT5 A;  2W2Q E;  2XC5 L;  4ZH8 B;  5K0H B;  2P28 B;  2Y81 B;  1IQH L;  4O02 B;  1FAK L;  3BT2 A;  1IOX A;  1NQL B;  4BTI A;  2AYL A;  1L5G B;  1IJQ A;  1JV2 B;  2XC0 L;  3V64 C;  2Y5F L;  5L30 L;  4CSY A;  1HCG B;  4X8S L;  4NA9 L;  2Y80 B;  3C9A C;  3NT1 A;  4JZD L;  1A3P A;  1Q4G A;  4MMY B;  2P3F L;  1M1X B;  5IKQ A;  3KK6 A;  2BQ6 A;  1LPZ A;  1CEJ A;  3LC3 B;  2CJI B;  1YUF A;  4ISH L;  1APQ A;  2ADX A;  1ATB A;  4BTU A;  1P9J A;  4ZHA B;  4XLW A;  4CUE A;  1NPE B;  2BQW A;  3NTB A;  1IOE L;  2Y5H L;  1TPG A;  1LQD A;  2B7D L;  4Y7A B;  1WU1 B;  3NJP C;  2P94 L;  1LMM A;  1NT0 A;  2P3T A;  2RA0 L;  3LAQ A;  2W26 B;  2WPK E;  4Z0L A;  3QMO A;  1G2L B;  4X8U L;  3TGF A;  1COU A;  1FAX L;  4YT7 L;  1G1R A;  2BOU A;  2RNL A;  1J9C L;  1PGE A;  2XBY L;  1IGZ A;  1KLO A;  2BOH A;  3EGF A;  5CKQ A;  3CS7 L;  3Q3K B;  2H9E C;  4BDX A;  2Y7Z B;  2VWM K;  3P5B L;  1XKA L;  4ZXY L;  2YGQ A;  2XBW L;  3LTF B;  2BQ7 A;  2OYE P;  1IP0 A;  1HT8 A;  3TK5 B;  2VVV L;  3CA7 A;  3KQB L;  3FCS B;  1EPG A;  1PXX A;  2W2N E;  1HAF A;  2RHP A;  1DQB A;  1EGF A;  2FD6 A;  3R05 A;  2I9A A;  1JL9 A;  5IKR A;  1FJS L;  1ADX A;  5I46 L;  1FF7 A;  2WPL E;  1KLJ L;  2YGP A;  5JBB E;  1W8B L;  3IJE B;  3LIW B;  1YUG A;  5FDQ A;  3IIT B;  1IQK L;  2MHP A;  3K9X A;  3ASI A;  2DDU A;  1EMN A;  1EQG A;  3BT1 A;  1CCF A;  4ZXX L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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