2WFNA

Filamin a actin binding domain
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
238
structure length
227
Chain Sequence
WKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Human Filamin a Actin-Binding Domain
pubmed doi rcsb
molecule tags Contractile protein
source organism Homo sapiens
molecule keywords FILAMIN-A
total genus 67
structure length 227
sequence length 238
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-04-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 2wfnA01
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 2wfnA02
2L3GA 2R8UA 2R0OA 2K2RA 1AOAA 3JALM 3HOPA 1PA7A 3I6XA 1WYMA 1DXXA 1RT8A 5L0OA 4EDLA 3JARM 5BVRA 2VZDA 1SH5A 4EDNA 1VKAA 1PXYA 1P5SA 5A37A 4TXIA 3HORA 1WYOA 2JV9A 5A38A 2D87A 2VZIB 4B7LA 5J8EA 3KMUB 2D85A 3CO1A 1SH6A 1UEGA 4EDMA 1P2XA 3KMWB 1H67A 1WYPA 1TJTA 2EE7A 1MB8A 2VZCA 3HOCA 2WA7A 1QAGA 2EYIA 3KY9A 1V5KA 1WKUA 1WYQA 3REPB 2D89A 4Q58A 1WIXA 2YRNA 4Q59A 2RR8A 1BKRA 1UJOA 1WYNA 1WYLA 2WA6A 2QJXA 2EYNA 2E9KA 5A36A 2WA5A 2VZGB 5A4BA 4Q57B 2WFNA 2DK9A 2D86A 3JAKM 1AA2A 1WYRA 3F7PA 3FERA 2D88A 2K3SA 2QJZA 1BHDA 4TXKA 1WJOA
chains in the Genus database with same CATH superfamily
3VP7A 2L3GA 4LVRA 2R8UA 2R0OA 2K2RA 2VE7A 1AOAA 3JALM 3HOPA 1PA7A 3I6XA 1WYMA 1DXXA 1RT8A 5L0OA 4EDLA 3JARM 2HL8A 5BVRA 2VE7C 2VZDA 1SH5A 4LVPA 4EDNA 1VKAA 1PXYA 1P5SA 5A37A 2HKPA 4TXIA 2EQOA 3HORA 1WYOA 2JV9A 4DDPA 5A38A 2D87A 2HL9A 5FMUA 2VZIB 4B7LA 5J8EA 3KMUB 2D85A 2WE6A 3CO1A 1SH6A 1UEGA 5FMTA 4EDMA 2IGPA 1P2XA 3KMWB 1H67A 4TXKA 1WYPA 2WDTA 1TJTA 3EAYA 2EE7A 1MB8A 2VZCA 3HOCA 2WA7A 1QAGA 2EYIA 3KY9A 1V5KA 1WKUA 1EUVA 1WYQA 3REPB 2D89A 4Q58A 1WIXA 2YRNA 4Q59A 2RR8A 1BKRA 1UJOA 1WYNA 1WYLA 2WA6A 2QJXA 2EYNA 2E9KA 5A36A 2VZGB 5A4BA 4Q57B 2WFNA 2DK9A 2D86A 3JAKM 1AA2A 1WYRA 3F7PA 3FERA 2D88A 2K3SA 2QJZA 1BHDA 2WA5A 1WJOA
chains in the Genus database with same CATH topology
2L3GA 2R8UA 2R0OA 2K2RA 1AOAA 3JALM 3HOPA 1PA7A 3I6XA 1WYMA 1DXXA 1RT8A 5L0OA 4EDLA 3JARM 5BVRA 2VZDA 1SH5A 4EDNA 1VKAA 1PXYA 1P5SA 5A37A 4TXIA 3HORA 1WYOA 2JV9A 5A38A 2D87A 2VZIB 4B7LA 5J8EA 3KMUB 2D85A 3CO1A 1SH6A 1UEGA 4EDMA 1P2XA 3KMWB 1H67A 1WYPA 1TJTA 2EE7A 1MB8A 2VZCA 3HOCA 2WA7A 1QAGA 2EYIA 3KY9A 1V5KA 1WKUA 1WYQA 3REPB 2D89A 4Q58A 1WIXA 2YRNA 4Q59A 2RR8A 1BKRA 1UJOA 1WYNA 1WYLA 2WA6A 2QJXA 2EYNA 2E9KA 5A36A 2WA5A 2VZGB 5A4BA 4Q57B 2WFNA 2DK9A 2D86A 3JAKM 1AA2A 1WYRA 3F7PA 3FERA 2D88A 2K3SA 2QJZA 1BHDA 4TXKA 1WJOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L3G A;  2R8U A;  2R0O A;  2K2R A;  1AOA A;  3JAL M;  3HOP A;  1PA7 A;  3I6X A;  1WYM A;  1DXX A;  1RT8 A;  5L0O A;  4EDL A;  3JAR M;  5BVR A;  2VZD A;  1SH5 A;  4EDN A;  1VKA A;  1PXY A;  1P5S A;  5A37 A;  4TXI A;  3HOR A;  1WYO A;  2JV9 A;  5A38 A;  2D87 A;  2VZI B;  4B7L A;  5J8E A;  3KMU B;  2D85 A;  3CO1 A;  1SH6 A;  1UEG A;  4EDM A;  1P2X A;  3KMW B;  1H67 A;  1WYP A;  1TJT A;  2EE7 A;  1MB8 A;  2VZC A;  3HOC A;  2WA7 A;  1QAG A;  2EYI A;  3KY9 A;  1V5K A;  1WKU A;  1WYQ A;  3REP B;  2D89 A;  4Q58 A;  1WIX A;  2YRN A;  4Q59 A;  2RR8 A;  1BKR A;  1UJO A;  1WYN A;  1WYL A;  2WA6 A;  2QJX A;  2EYN A;  2E9K A;  5A36 A;  2WA5 A;  2VZG B;  5A4B A;  4Q57 B;  2WFN A;  2DK9 A;  2D86 A;  3JAK M;  1AA2 A;  1WYR A;  3F7P A;  3FER A;  2D88 A;  2K3S A;  2QJZ A;  1BHD A;  4TXK A;  1WJO A; 
#chains in the Genus database with same CATH topology
 3VP7 A;  2L3G A;  4LVR A;  2R8U A;  2R0O A;  2K2R A;  2VE7 A;  1AOA A;  3JAL M;  3HOP A;  1PA7 A;  3I6X A;  1WYM A;  1DXX A;  1RT8 A;  5L0O A;  4EDL A;  3JAR M;  2HL8 A;  5BVR A;  2VE7 C;  2VZD A;  1SH5 A;  4LVP A;  4EDN A;  1VKA A;  1PXY A;  1P5S A;  5A37 A;  2HKP A;  4TXI A;  2EQO A;  3HOR A;  1WYO A;  2JV9 A;  4DDP A;  5A38 A;  2D87 A;  2HL9 A;  5FMU A;  2VZI B;  4B7L A;  5J8E A;  3KMU B;  2D85 A;  2WE6 A;  3CO1 A;  1SH6 A;  1UEG A;  5FMT A;  4EDM A;  2IGP A;  1P2X A;  3KMW B;  1H67 A;  4TXK A;  1WYP A;  2WDT A;  1TJT A;  3EAY A;  2EE7 A;  1MB8 A;  2VZC A;  3HOC A;  2WA7 A;  1QAG A;  2EYI A;  3KY9 A;  1V5K A;  1WKU A;  1EUV A;  1WYQ A;  3REP B;  2D89 A;  4Q58 A;  1WIX A;  2YRN A;  4Q59 A;  2RR8 A;  1BKR A;  1UJO A;  1WYN A;  1WYL A;  2WA6 A;  2QJX A;  2EYN A;  2E9K A;  5A36 A;  2VZG B;  5A4B A;  4Q57 B;  2WFN A;  2DK9 A;  2D86 A;  3JAK M;  1AA2 A;  1WYR A;  3F7P A;  3FER A;  2D88 A;  2K3S A;  2QJZ A;  1BHD A;  2WA5 A;  1WJO A; 
#chains in the Genus database with same CATH homology
 2L3G A;  2R8U A;  2R0O A;  2K2R A;  1AOA A;  3JAL M;  3HOP A;  1PA7 A;  3I6X A;  1WYM A;  1DXX A;  1RT8 A;  5L0O A;  4EDL A;  3JAR M;  5BVR A;  2VZD A;  1SH5 A;  4EDN A;  1VKA A;  1PXY A;  1P5S A;  5A37 A;  4TXI A;  3HOR A;  1WYO A;  2JV9 A;  5A38 A;  2D87 A;  2VZI B;  4B7L A;  5J8E A;  3KMU B;  2D85 A;  3CO1 A;  1SH6 A;  1UEG A;  4EDM A;  1P2X A;  3KMW B;  1H67 A;  1WYP A;  1TJT A;  2EE7 A;  1MB8 A;  2VZC A;  3HOC A;  2WA7 A;  1QAG A;  2EYI A;  3KY9 A;  1V5K A;  1WKU A;  1WYQ A;  3REP B;  2D89 A;  4Q58 A;  1WIX A;  2YRN A;  4Q59 A;  2RR8 A;  1BKR A;  1UJO A;  1WYN A;  1WYL A;  2WA6 A;  2QJX A;  2EYN A;  2E9K A;  5A36 A;  2WA5 A;  2VZG B;  5A4B A;  4Q57 B;  2WFN A;  2DK9 A;  2D86 A;  3JAK M;  1AA2 A;  1WYR A;  3F7P A;  3FER A;  2D88 A;  2K3S A;  2QJZ A;  1BHD A;  4TXK A;  1WJO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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