2WN4A

Structural basis for substrate recognition in the enzymatic component of adp-ribosyltransferase toxin cdta from clostridium difficile
Total Genus 134
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
134
sequence length
393
structure length
391
Chain Sequence
RKEAERIEQKLERSEKEALESYKKDSVEISKYSQTRNYFYDYQIEANSREKEYKELRNAISKNKIDKPMYVYYFESPEKFAFNKVIRTENQNEISLEKFNEFKETIQNKLFKQDGFKDISLYEPGKGDEKPTPLLMHLKLPRNTGMLPYTNTVSTLIEQGYSIKIDKIVRIVIDGKHYIKAEASVVSSLDFKDDVSKGDSWGKANYNDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPVNNPNPELDSKITNIENALKREPIPTNLTVYRRSGPQEFGLTLTSPEYDFNKLENIDAFKSKWEGQALSYPNFISTSIGSVNMSAFAKRKIVLRITIPKGSPGAYLSAIPGYAGEYEVLLNHGSKFKINKIDSYKDGTITKLIVDATLIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Substrate Recognition in the Enzymatic Component of Adp-Ribosyltransferase Toxin Cdta from Clostridium Difficile.
pubmed doi rcsb
molecule keywords ADP-RIBOSYLTRANSFERASE ENZYMATIC COMPONENT
molecule tags Transferase
source organism Clostridium difficile
total genus 134
structure length 391
sequence length 393
ec nomenclature
pdb deposition date 2009-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn4A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn4A01
4FMLA 2C8AA 4ELNA 2A78B 2GWLA 3BW8A 2C8BX 4PKWA 2C8DA 3BUZA 1ZXVA 3NTSA 1R4BA 2A9KB 5GTTA 4H03A 1GZEA 4TR5A 2C8FE 4XSGB 1PWPA 1OJZA 4DV8A 1G24A 2C8CA 2WN7A 1PWWA 2WN4A 2J3VA 4PKVA 4H0XA 1OG3A 5D1UA 2J3XA 4XM8A 1GIRA 4H0TA 1OJQA 2J3ZA 4GF1A 5BWMB 2C8HA 1QS2A 1J7NA 2C8EE 2GWMA 4H0VA 4XM7A 5H04A 2C8GA 1GY0A 1UZIA 4XSHB 4PKTA 4FXQA 4PKRA 2C89A 1PWVA 1OG4A 4XM6A 5DZQA 2WN8A 2WN5A 1PWQA 1YQYA 4PKQA 4GY2A 4WF6A 1GXYA 4PKSA 4FK7A 4H0YA 1GXZA 1JKYA 1GZFA 1OG1A 1R45A 5D1TA 1GIQA 2WN6A 5H03A 3U0JA 4PKUA 2BOVB 1QS1A 5D1SA 1PWUA
chains in the Genus database with same CATH superfamily
4FMLA 2C8AA 4ELNA 2A78B 2GWLA 3BW8A 2C8BX 4PKWA 2C8DA 3BUZA 1ZXVA 3NTSA 1R4BA 2A9KB 5GTTA 4H03A 1GZEA 4TR5A 2C8FE 4XSGB 1PWPA 1OJZA 4DV8A 1G24A 2C8CA 2WN7A 1PWWA 2WN4A 2J3VA 4PKVA 4H0XA 1OG3A 5D1UA 2J3XA 4XM8A 1GIRA 4H0TA 1OJQA 2J3ZA 4GF1A 5BWMB 2C8HA 1QS2A 1J7NA 2C8EE 2GWMA 4H0VA 4XM7A 5H04A 2C8GA 1GY0A 1UZIA 4XSHB 4PKTA 4FXQA 4PKRA 2C89A 1PWVA 1OG4A 4XM6A 5DZQA 2WN8A 2WN5A 1PWQA 1YQYA 4PKQA 4GY2A 4WF6A 1GXYA 4PKSA 4FK7A 4H0YA 1GXZA 1JKYA 1GZFA 1OG1A 1R45A 5D1TA 1GIQA 2WN6A 5H03A 3U0JA 4PKUA 2BOVB 1QS1A 5D1SA 1PWUA
chains in the Genus database with same CATH topology
4FMLA 2C8AA 4ELNA 2A78B 2GWLA 3BW8A 2C8BX 4PKWA 2C8DA 3BUZA 1ZXVA 3NTSA 1R4BA 2A9KB 5GTTA 4H03A 1GZEA 4TR5A 2C8FE 4XSGB 1PWPA 1OJZA 4DV8A 1G24A 2C8CA 2WN7A 1PWWA 2WN4A 2J3VA 4PKVA 4H0XA 1OG3A 5D1UA 2J3XA 4XM8A 1GIRA 4H0TA 1OJQA 2J3ZA 4GF1A 5BWMB 2C8HA 1QS2A 1J7NA 2C8EE 2GWMA 4H0VA 4XM7A 5H04A 2C8GA 1GY0A 1UZIA 4XSHB 4PKTA 4FXQA 4PKRA 2C89A 1PWVA 1OG4A 4XM6A 5DZQA 2WN8A 2WN5A 1PWQA 1YQYA 4PKQA 4GY2A 4WF6A 1GXYA 4PKSA 4FK7A 4H0YA 1GXZA 1JKYA 1GZFA 1OG1A 1R45A 5D1TA 1GIQA 2WN6A 5H03A 3U0JA 4PKUA 2BOVB 1QS1A 5D1SA 1PWUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FML A;  2C8A A;  4ELN A;  2A78 B;  2GWL A;  3BW8 A;  2C8B X;  4PKW A;  2C8D A;  3BUZ A;  1ZXV A;  3NTS A;  1R4B A;  2A9K B;  5GTT A;  4H03 A;  1GZE A;  4TR5 A;  2C8F E;  4XSG B;  1PWP A;  1OJZ A;  4DV8 A;  1G24 A;  2C8C A;  2WN7 A;  1PWW A;  2WN4 A;  2J3V A;  4PKV A;  4H0X A;  1OG3 A;  5D1U A;  2J3X A;  4XM8 A;  1GIR A;  4H0T A;  1OJQ A;  2J3Z A;  4GF1 A;  5BWM B;  2C8H A;  1QS2 A;  1J7N A;  2C8E E;  2GWM A;  4H0V A;  4XM7 A;  5H04 A;  2C8G A;  1GY0 A;  1UZI A;  4XSH B;  4PKT A;  4FXQ A;  4PKR A;  2C89 A;  1PWV A;  1OG4 A;  4XM6 A;  5DZQ A;  2WN8 A;  2WN5 A;  1PWQ A;  1YQY A;  4PKQ A;  4GY2 A;  4WF6 A;  1GXY A;  4PKS A;  4FK7 A;  4H0Y A;  1GXZ A;  1JKY A;  1GZF A;  1OG1 A;  1R45 A;  5D1T A;  1GIQ A;  2WN6 A;  5H03 A;  3U0J A;  4PKU A;  2BOV B;  1QS1 A;  5D1S A;  1PWU A; 
#chains in the Genus database with same CATH topology
 4FML A;  2C8A A;  4ELN A;  2A78 B;  2GWL A;  3BW8 A;  2C8B X;  4PKW A;  2C8D A;  3BUZ A;  1ZXV A;  3NTS A;  1R4B A;  2A9K B;  5GTT A;  4H03 A;  1GZE A;  4TR5 A;  2C8F E;  4XSG B;  1PWP A;  1OJZ A;  4DV8 A;  1G24 A;  2C8C A;  2WN7 A;  1PWW A;  2WN4 A;  2J3V A;  4PKV A;  4H0X A;  1OG3 A;  5D1U A;  2J3X A;  4XM8 A;  1GIR A;  4H0T A;  1OJQ A;  2J3Z A;  4GF1 A;  5BWM B;  2C8H A;  1QS2 A;  1J7N A;  2C8E E;  2GWM A;  4H0V A;  4XM7 A;  5H04 A;  2C8G A;  1GY0 A;  1UZI A;  4XSH B;  4PKT A;  4FXQ A;  4PKR A;  2C89 A;  1PWV A;  1OG4 A;  4XM6 A;  5DZQ A;  2WN8 A;  2WN5 A;  1PWQ A;  1YQY A;  4PKQ A;  4GY2 A;  4WF6 A;  1GXY A;  4PKS A;  4FK7 A;  4H0Y A;  1GXZ A;  1JKY A;  1GZF A;  1OG1 A;  1R45 A;  5D1T A;  1GIQ A;  2WN6 A;  5H03 A;  3U0J A;  4PKU A;  2BOV B;  1QS1 A;  5D1S A;  1PWU A; 
#chains in the Genus database with same CATH homology
 4FML A;  2C8A A;  4ELN A;  2A78 B;  2GWL A;  3BW8 A;  2C8B X;  4PKW A;  2C8D A;  3BUZ A;  1ZXV A;  3NTS A;  1R4B A;  2A9K B;  5GTT A;  4H03 A;  1GZE A;  4TR5 A;  2C8F E;  4XSG B;  1PWP A;  1OJZ A;  4DV8 A;  1G24 A;  2C8C A;  2WN7 A;  1PWW A;  2WN4 A;  2J3V A;  4PKV A;  4H0X A;  1OG3 A;  5D1U A;  2J3X A;  4XM8 A;  1GIR A;  4H0T A;  1OJQ A;  2J3Z A;  4GF1 A;  5BWM B;  2C8H A;  1QS2 A;  1J7N A;  2C8E E;  2GWM A;  4H0V A;  4XM7 A;  5H04 A;  2C8G A;  1GY0 A;  1UZI A;  4XSH B;  4PKT A;  4FXQ A;  4PKR A;  2C89 A;  1PWV A;  1OG4 A;  4XM6 A;  5DZQ A;  2WN8 A;  2WN5 A;  1PWQ A;  1YQY A;  4PKQ A;  4GY2 A;  4WF6 A;  1GXY A;  4PKS A;  4FK7 A;  4H0Y A;  1GXZ A;  1JKY A;  1GZF A;  1OG1 A;  1R45 A;  5D1T A;  1GIQ A;  2WN6 A;  5H03 A;  3U0J A;  4PKU A;  2BOV B;  1QS1 A;  5D1S A;  1PWU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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