2WO8A

Mmp12 complex with a beta hydroxy carboxylic acid
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
163
structure length
163
Chain Sequence
MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYGDPKE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Identification of Beta-Hydroxy Carboxylic Acids as Selective Mmp-12 Inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords MACROPHAGE METALLOELASTASE
total genus 47
structure length 163
sequence length 163
chains with identical sequence B, C, D
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2009-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2wo8A00
3ZVSA 5D1UA 2DDFA 1DMTA 3LJGA 2D1NA 1OS9A 4JPAA 3B2ZA 1FBLA 2W0DA 2MZIA 4H2EA 1YOUA 3LILA 4GUYA 4G9LA 3EDZA 1ZTQA 1JANA 2W13A 2W14A 1XFWA 5I2ZA 1ATLA 4G0DA 3WV2A 1R1IA 1YP1A 1OS2A 3KECA 3F16A 2O36A 4GF1A 1O0TA 1JH1A 4JA1A 3HBUP 3LMCA 1UEAA 1MMRA 1OM7A 1HTDA 3DPEA 3F1AA 5I4OA 3Q2GA 1IAEA 4PKQA 3KMEA 1H71P 2V4BA 2OXUA 1G12A 1G4KA 2OVZA 4QKZA 1S4BP 1PWUA 2OW2A 2XS3A 1BZSA 4H30A 4AIGA 1KUHA 2W12A 1KUFA 3P24A 3AYKA 3DWBA 1GO8P 1MMPA 2CKIA 4XM6A 3EWJA 2X3AA 2A8HA 3F19A 1JJ9A 2I47A 5CZMA 1PWQA 1ND1A 1QICA 1O0QA 4WKIA 1EUBA 1Y93A 3AYUA 1FLSA 3GBOA 3EDHA 2O3EA 2FV9A 1DTHA 3B8ZA 4DF9A 2N8RA 4I03A 5B5PA 3EHYA 1ZXVA 1BQQM 5JMYA 2HU6A 1D8MA 1GKCA 1CQRA 3K7NA 2Y6DA 1AYKA 3V96B 3O64A 3TSKA 2RJQA 1MNCA 1BKCI 4H49A 2OZRA 1YCMA 4EFSA 1XURA 3N2UA 3ELMA 1R55A 1UMTA 1K7GA 2MLRA 4J4MA 1GE6A 4R3VA 3TT4A 4GR0A 1SMPA 3HY9A 3LIRA 1D5JA 3KWVC 3SHIA 5D3CA 2L0RA 2WO9A 1SLMA 1XFYA 5D2BA 1Y0VA 4DD8A 5CXAA 3LQ0A 1KBCA 2POJA 1HY7A 2OXZA 1SLNA 5H8XA 4WKEA 1I1IP 1HOVA 4FXYP 5B5OA 1G49A 3CKIA 2OW1A 3BA0A 4GWMA 3KRYA 4H82A 3K7LA 2Z2DA 3LKAA 1EAKA 2JSDA 1B8YA 3LJZA 4GWNA 3F15A 1BM6A 1JIZA 4AYKA 1BSWA 1ZP5A 3LUNA 4H1QA 4PKWA 4JQGA 1GE5A 2AYKA 3KMCA 1CAQA 1JIWP 4XBHA 4AUOA 1KUGA 4GQLA 4XM8A 1Z3JA 4Q1LA 3E8RA 3TVCA 2MZEA 4FXQA 1OM6A 4JIJA 1XFUA 2XS4A 5L79A 1D8FA 1SATA 5I43A 1QIAA 1CIZA 4ZR5A 2ERQA 3N2VA 2OVXA 1CGFA 1RMZA 2D1OA 2ERPA 2DDYA 2USNA 5D1TA 2X3BA 3P1VA 1QUAA 1JK3A 1R1HA 5BOTA 1XUCA 1YQYA 3L0TA 1GKDA 4AXQA 2OI0A 3DL1A 1G9KA 1HFCA 1ZVXA 4GR3A 3L0VA 1GE7A 830CA 1BUVM 3LK8A 2WO8A 1QJIA 3HB2P 2MLSA 1IADA 2YIGA 3RTSA 1B3DA 5D1SA 4PKTA 4ILWD 3LIKA 1GO7P 1G05A 4DV8A 1UMSA 2FV5A 2X3CA 1BIWA 5CUHA 1ZS0A 2OY4A 3LEAA 3O2XA 1XFZA 4L19A 2PJTA 4IN9A 1BKCA 3F17A 3U1RA 1C3IA 1Q3AA 4I35A 4GR8A 4IJOA 5I3MA 4XCTA 1QIBA 1K7QA 2JT5A 3LJTA 1ASTA 1D7XA 2QPJA 1A85A 4FVLA 1A86A 3RTTA 1JAPA 1IACA 4H76A 1OO9A 3UVCA 3AIGA 4H3XA 2YB9A 1SU3A 1JKYA 1L6JA 4CTHA 2X7MA 2JT6A 3VTGA 3TS4A 2J83A 4PKUA 4FU4A 966CA 5I12A 2OW0A 1C8TA 3LQBA 2W15A 2JIHA 3EDIA 1RM8A 1KUKA 3WV1A 3DPFA 1MMQA 2JNPA 2K9CA 1J7NA 4HMAA 3HBVP 1XUDA 4H84A 1Y8JA 3HY7A 1K7IA 1KAPP 3G5CA 4ON1A 3HDAP 3LGPA 2E3XA 2J0TA 1PWVA 3HYGA 1AF0A 1EB6A 1CGLA 2WOAA 3VI1A 1C7KA 1AKLA 1MMBA 2DW2A 3EDGA 4A7BA 1HV5A 3DNGA 1ZXCA 1GXDA 3NX7A 1JAOA 3G42A 1PWPA 5LABA 1BQOA 4IUWA 1CXVA 1FM1A 3Q2HA 1WNIA 5BOYA 1CGEA 3WV3A 2DW0A 1CK7A 4XM7A 1OMJA 1UTZA 5L7FA 4L63A 4HX3A 3KEJA 1HFSA 5I0LA 3USNA 4JP4A 1XFVA 2Y6CA 2EROA 3EHXA 1I76A 1R54A 3I7IA 1KUIA 1IABA 3HDBA 4WF6A 3MA2A 1JAQA 3KEKA 2TCLA 4PKVA 4WK7A 2AIGP 4DPEA 2E2DA 2OW9A 2CLTA 3F18A 1USNA 1ROSA 3B92A 4PKSA 3I7GA 1OM8A 2MZHA 456CA 2OY2A 2SRTA 3ZXHA 1R1JA 4L6TA 5BPAA 5D7WA 1SRPA 1UTTA 3ZUKA 1IAGA 2K2GA 1BKCE 3OHLA 3DSLA 4WZVA 2KRJA 1IAAA 2DW1A 1BUDA 1XFXA 3LE9A 1QJJA 3LUMA 4A3WA 3KHIA 2RJPA 1PWWA 4PKRA 2OXWA 3OHOA 1I73A
chains in the Genus database with same CATH superfamily
3ZVSA 5D1UA 2DDFA 1DMTA 3LJGA 2D1NA 1OS9A 4JPAA 3B2ZA 1FBLA 2W0DA 2MZIA 4H2EA 1YOUA 3LILA 4GUYA 4G9LA 3EDZA 1ZTQA 1JANA 2W13A 2W14A 1XFWA 5I2ZA 1ATLA 4G0DA 3WV2A 1R1IA 1YP1A 1OS2A 3KECA 3F16A 2O36A 4GF1A 1O0TA 1JH1A 4JA1A 3HBUP 3LMCA 1UEAA 1MMRA 1OM7A 1HTDA 3DPEA 3F1AA 5I4OA 3Q2GA 1IAEA 4PKQA 3KMEA 1H71P 2V4BA 2OXUA 1G12A 1G4KA 2OVZA 4QKZA 1S4BP 1PWUA 2OW2A 2XS3A 1BZSA 4H30A 4AIGA 1KUHA 2W12A 1KUFA 3DTIA 3P24A 3AYKA 3DWBA 1GO8P 1MMPA 2CKIA 4XM6A 1OZ9A 3EWJA 2X3AA 2A8HA 3F19A 1JJ9A 2I47A 5CZMA 1PWQA 1ND1A 1QICA 1O0QA 4WKIA 1EUBA 1Y93A 3AYUA 1FLSA 3GBOA 3EDHA 2O3EA 2FV9A 1DTHA 3B8ZA 4DF9A 2N8RA 4I03A 5B5PA 3EHYA 1ZXVA 1BQQM 5JMYA 2HU6A 1D8MA 1GKCA 1CQRA 3K7NA 2Y6DA 1AYKA 3V96B 3O64A 3TSKA 2RJQA 1MNCA 1BKCI 4H49A 2OZRA 1YCMA 4EFSA 1XURA 3N2UA 3ELMA 1R55A 1UMTA 1K7GA 2MLRA 4J4MA 1XM5A 1GE6A 4R3VA 3TT4A 4GR0A 1SMPA 1TVIA 3HY9A 3LIRA 1D5JA 3KWVC 3SHIA 5D3CA 2L0RA 2WO9A 1SLMA 1XFYA 5D2BA 1Y0VA 4DD8A 5CXAA 3LQ0A 3DTEA 1KBCA 2POJA 1HY7A 2OXZA 1SLNA 5H8XA 4WKEA 1I1IP 1HOVA 4FXYP 5B5OA 1G49A 3CKIA 2OW1A 3BA0A 4GWMA 3KRYA 4H82A 3K7LA 2Z2DA 3LKAA 1EAKA 2JSDA 1B8YA 3LJZA 4GWNA 3F15A 1BM6A 1JIZA 4AYKA 1BSWA 1ZP5A 3LUNA 4H1QA 4PKWA 4JQGA 1GE5A 2AYKA 3KMCA 1CAQA 1JIWP 4XBHA 4AUOA 1KUGA 4GQLA 4XM8A 1Z3JA 4Q1LA 3E8RA 3TVCA 2MZEA 4FXQA 1OM6A 4JIJA 1XFUA 2XS4A 5L79A 1D8FA 1SATA 5I43A 1QIAA 1CIZA 4ZR5A 2ERQA 3N2VA 2OVXA 1CGFA 1RMZA 2D1OA 2ERPA 2DDYA 2USNA 5D1TA 2X3BA 3P1VA 1QUAA 1JK3A 1R1HA 5BOTA 1XUCA 1YQYA 3L0TA 1GKDA 4AXQA 2OI0A 3DL1A 1G9KA 1HFCA 1ZVXA 4GR3A 2YUFA 3L0VA 1GE7A 830CA 1BUVM 3LK8A 2WO8A 1QJIA 3HB2P 2MLSA 1IADA 2YIGA 3RTSA 1B3DA 5D1SA 4PKTA 4ILWD 3LIKA 1GO7P 1G05A 4DV8A 1UMSA 2FV5A 2X3CA 1BIWA 5CUHA 1ZS0A 2OY4A 3LEAA 3O2XA 1XFZA 4L19A 2PJTA 4IN9A 1BKCA 3F17A 3U1RA 1C3IA 1Q3AA 4I35A 4GR8A 4IJOA 5I3MA 4XCTA 1QIBA 1K7QA 2JT5A 3LJTA 1ASTA 1D7XA 2QPJA 1A85A 4FVLA 1A86A 3RTTA 1JAPA 1IACA 4H76A 1OO9A 3UVCA 3AIGA 4H3XA 2YB9A 1SU3A 1JKYA 1L6JA 4CTHA 2X7MA 2JT6A 3VTGA 3TS4A 2J83A 4PKUA 4FU4A 966CA 5I12A 2OW0A 1C8TA 3LQBA 2W15A 2JIHA 3EDIA 1RM8A 1KUKA 3WV1A 3DPFA 1MMQA 2JNPA 2K9CA 1J7NA 4HMAA 3HBVP 1XUDA 4H84A 1Y8JA 3HY7A 1K7IA 1KAPP 3G5CA 4ON1A 3HDAP 3LGPA 2E3XA 2J0TA 1PWVA 3HYGA 1AF0A 1EB6A 1CGLA 2WOAA 3VI1A 1C7KA 1AKLA 1MMBA 2DW2A 3EDGA 4A7BA 1HV5A 3DNGA 1ZXCA 1GXDA 3NX7A 1JAOA 3G42A 1PWPA 5LABA 1BQOA 4IUWA 1CXVA 1FM1A 3Q2HA 1WNIA 5BOYA 1CGEA 3WV3A 2DW0A 1CK7A 4XM7A 1OMJA 1UTZA 5L7FA 4L63A 4HX3A 3KEJA 1HFSA 5I0LA 3USNA 4JP4A 1XFVA 2Y6CA 2EROA 3EHXA 1I76A 1R54A 3I7IA 1KUIA 1IABA 3HDBA 4WF6A 3DTKA 3MA2A 1JAQA 3KEKA 2TCLA 4PKVA 4WK7A 2AIGP 4DPEA 2E2DA 2OW9A 2CLTA 3F18A 1USNA 1ROSA 3B92A 4PKSA 3I7GA 1OM8A 1XAXA 2MZHA 4L7AA 456CA 2OY2A 2SRTA 3ZXHA 1R1JA 4L6TA 5BPAA 5D7WA 1SRPA 1UTTA 3ZUKA 1IAGA 2K2GA 1BKCE 3OHLA 3DSLA 4WZVA 2KRJA 1IAAA 2DW1A 1BUDA 1XFXA 3LE9A 1QJJA 3LUMA 4A3WA 3KHIA 2RJPA 1PWWA 4PKRA 2OXWA 3OHOA 1I73A
chains in the Genus database with same CATH topology
3ZVSA 5D1UA 2DDFA 1DMTA 3LJGA 2D1NA 1OS9A 4JPAA 3B2ZA 1FBLA 2W0DA 2MZIA 4H2EA 1YOUA 3LILA 4GUYA 4G9LA 3EDZA 1ZTQA 1JANA 2W13A 2W14A 1XFWA 5I2ZA 1ATLA 4G0DA 3WV2A 1R1IA 1YP1A 1OS2A 3KECA 3F16A 2O36A 4GF1A 1O0TA 1JH1A 4JA1A 3HBUP 3LMCA 1UEAA 1MMRA 1OM7A 1HTDA 3DPEA 3F1AA 5I4OA 3Q2GA 1IAEA 4PKQA 3KMEA 1H71P 2V4BA 2OXUA 1G12A 1G4KA 2OVZA 4QKZA 1S4BP 1PWUA 2OW2A 2XS3A 1BZSA 4H30A 4AIGA 1KUHA 2W12A 1KUFA 3DTIA 3P24A 3AYKA 3DWBA 1GO8P 1MMPA 2CKIA 4XM6A 3EWJA 2X3AA 2A8HA 3F19A 1JJ9A 2I47A 5CZMA 1PWQA 1ND1A 1QICA 1O0QA 4WKIA 1EUBA 1Y93A 3AYUA 1FLSA 3GBOA 3EDHA 2O3EA 2FV9A 1DTHA 3B8ZA 4DF9A 2N8RA 4I03A 5B5PA 3EHYA 1ZXVA 1BQQM 5JMYA 2HU6A 1D8MA 1GKCA 1CQRA 3K7NA 2Y6DA 1AYKA 3V96B 3O64A 3TSKA 2RJQA 1MNCA 1BKCI 4H49A 2OZRA 1YCMA 4EFSA 1XURA 3N2UA 3ELMA 1R55A 1UMTA 1K7GA 2MLRA 4J4MA 1GE6A 4R3VA 3TT4A 4GR0A 1SMPA 3HY9A 3LIRA 1D5JA 3KWVC 3SHIA 5D3CA 2L0RA 2WO9A 1SLMA 1XFYA 5D2BA 1Y0VA 4DD8A 5CXAA 3LQ0A 3DTEA 1KBCA 2POJA 1HY7A 2OXZA 1SLNA 5H8XA 4WKEA 1I1IP 1HOVA 4FXYP 5B5OA 1G49A 3CKIA 2OW1A 3BA0A 4GWMA 3KRYA 4H82A 3K7LA 2Z2DA 3LKAA 1EAKA 2JSDA 1B8YA 3LJZA 4GWNA 3F15A 1BM6A 1JIZA 4AYKA 1BSWA 1ZP5A 3LUNA 4H1QA 4PKWA 4JQGA 1GE5A 2AYKA 3KMCA 1CAQA 1JIWP 4XBHA 4AUOA 1KUGA 4GQLA 4XM8A 1Z3JA 4Q1LA 3E8RA 3TVCA 2MZEA 4FXQA 1OM6A 4JIJA 1XFUA 2XS4A 5L79A 1D8FA 1SATA 5I43A 1QIAA 1CIZA 4ZR5A 2ERQA 3N2VA 2OVXA 1CGFA 1RMZA 2D1OA 2ERPA 2DDYA 2USNA 5D1TA 2X3BA 3P1VA 1QUAA 1JK3A 1R1HA 5BOTA 1XUCA 1YQYA 3L0TA 1GKDA 4AXQA 2OI0A 3DL1A 1G9KA 1HFCA 1ZVXA 4GR3A 2YUFA 3L0VA 1GE7A 830CA 1BUVM 3LK8A 2WO8A 1QJIA 3HB2P 2MLSA 1IADA 2YIGA 3RTSA 1B3DA 5D1SA 4PKTA 4ILWD 3LIKA 1GO7P 1G05A 4DV8A 1UMSA 2FV5A 2X3CA 1BIWA 5CUHA 1ZS0A 2OY4A 3LEAA 3O2XA 1XFZA 4L19A 2PJTA 4IN9A 1BKCA 3F17A 3U1RA 1C3IA 1Q3AA 4I35A 4GR8A 4IJOA 5I3MA 4XCTA 1QIBA 1K7QA 2JT5A 3LJTA 1ASTA 1D7XA 2QPJA 1A85A 4FVLA 1A86A 3RTTA 1JAPA 1IACA 4H76A 1OO9A 3UVCA 3AIGA 4H3XA 2YB9A 1SU3A 1JKYA 1L6JA 4CTHA 2X7MA 2JT6A 3VTGA 3TS4A 2J83A 4PKUA 4FU4A 966CA 5I12A 2OW0A 1C8TA 3LQBA 2W15A 2JIHA 3EDIA 1RM8A 1KUKA 3WV1A 3DPFA 1MMQA 2JNPA 2K9CA 1J7NA 4HMAA 3HBVP 1XUDA 4H84A 1Y8JA 3HY7A 1K7IA 1KAPP 3G5CA 4ON1A 3HDAP 3LGPA 2E3XA 2J0TA 1PWVA 3HYGA 1AF0A 1EB6A 1CGLA 2WOAA 3VI1A 1C7KA 1AKLA 1MMBA 2DW2A 3EDGA 4A7BA 1HV5A 3DNGA 1ZXCA 1GXDA 3NX7A 1JAOA 3G42A 1PWPA 5LABA 1BQOA 4IUWA 1CXVA 1FM1A 3Q2HA 1WNIA 5BOYA 1CGEA 3WV3A 2DW0A 1CK7A 4XM7A 1OMJA 1UTZA 5L7FA 4L63A 4HX3A 3KEJA 1HFSA 5I0LA 3USNA 4JP4A 1XFVA 2Y6CA 2EROA 3EHXA 1I76A 1R54A 3I7IA 1KUIA 1IABA 3HDBA 4WF6A 3DTKA 3MA2A 1JAQA 3KEKA 2TCLA 4PKVA 4WK7A 2AIGP 4DPEA 2E2DA 2OW9A 2CLTA 3F18A 1USNA 1ROSA 3B92A 4PKSA 3I7GA 1OM8A 2MZHA 4L7AA 456CA 2OY2A 2SRTA 3ZXHA 1R1JA 4L6TA 5BPAA 5D7WA 1SRPA 1UTTA 3ZUKA 1IAGA 2K2GA 1BKCE 3OHLA 3DSLA 4WZVA 2KRJA 1IAAA 2DW1A 1BUDA 1XFXA 3LE9A 1QJJA 3LUMA 4A3WA 3KHIA 2RJPA 1PWWA 4PKRA 2OXWA 3OHOA 1I73A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZVS A;  5D1U A;  2DDF A;  1DMT A;  3LJG A;  2D1N A;  1OS9 A;  4JPA A;  3B2Z A;  1FBL A;  2W0D A;  2MZI A;  4H2E A;  1YOU A;  3LIL A;  4GUY A;  4G9L A;  3EDZ A;  1ZTQ A;  1JAN A;  2W13 A;  2W14 A;  1XFW A;  5I2Z A;  1ATL A;  4G0D A;  3WV2 A;  1R1I A;  1YP1 A;  1OS2 A;  3KEC A;  3F16 A;  2O36 A;  4GF1 A;  1O0T A;  1JH1 A;  4JA1 A;  3HBU P;  3LMC A;  1UEA A;  1MMR A;  1OM7 A;  1HTD A;  3DPE A;  3F1A A;  5I4O A;  3Q2G A;  1IAE A;  4PKQ A;  3KME A;  1H71 P;  2V4B A;  2OXU A;  1G12 A;  1G4K A;  2OVZ A;  4QKZ A;  1S4B P;  1PWU A;  2OW2 A;  2XS3 A;  1BZS A;  4H30 A;  4AIG A;  1KUH A;  2W12 A;  1KUF A;  3P24 A;  3AYK A;  3DWB A;  1GO8 P;  1MMP A;  2CKI A;  4XM6 A;  3EWJ A;  2X3A A;  2A8H A;  3F19 A;  1JJ9 A;  2I47 A;  5CZM A;  1PWQ A;  1ND1 A;  1QIC A;  1O0Q A;  4WKI A;  1EUB A;  1Y93 A;  3AYU A;  1FLS A;  3GBO A;  3EDH A;  2O3E A;  2FV9 A;  1DTH A;  3B8Z A;  4DF9 A;  2N8R A;  4I03 A;  5B5P A;  3EHY A;  1ZXV A;  1BQQ M;  5JMY A;  2HU6 A;  1D8M A;  1GKC A;  1CQR A;  3K7N A;  2Y6D A;  1AYK A;  3V96 B;  3O64 A;  3TSK A;  2RJQ A;  1MNC A;  1BKC I;  4H49 A;  2OZR A;  1YCM A;  4EFS A;  1XUR A;  3N2U A;  3ELM A;  1R55 A;  1UMT A;  1K7G A;  2MLR A;  4J4M A;  1GE6 A;  4R3V A;  3TT4 A;  4GR0 A;  1SMP A;  3HY9 A;  3LIR A;  1D5J A;  3KWV C;  3SHI A;  5D3C A;  2L0R A;  2WO9 A;  1SLM A;  1XFY A;  5D2B A;  1Y0V A;  4DD8 A;  5CXA A;  3LQ0 A;  1KBC A;  2POJ A;  1HY7 A;  2OXZ A;  1SLN A;  5H8X A;  4WKE A;  1I1I P;  1HOV A;  4FXY P;  5B5O A;  1G49 A;  3CKI A;  2OW1 A;  3BA0 A;  4GWM A;  3KRY A;  4H82 A;  3K7L A;  2Z2D A;  3LKA A;  1EAK A;  2JSD A;  1B8Y A;  3LJZ A;  4GWN A;  3F15 A;  1BM6 A;  1JIZ A;  4AYK A;  1BSW A;  1ZP5 A;  3LUN A;  4H1Q A;  4PKW A;  4JQG A;  1GE5 A;  2AYK A;  3KMC A;  1CAQ A;  1JIW P;  4XBH A;  4AUO A;  1KUG A;  4GQL A;  4XM8 A;  1Z3J A;  4Q1L A;  3E8R A;  3TVC A;  2MZE A;  4FXQ A;  1OM6 A;  4JIJ A;  1XFU A;  2XS4 A;  5L79 A;  1D8F A;  1SAT A;  5I43 A;  1QIA A;  1CIZ A;  4ZR5 A;  2ERQ A;  3N2V A;  2OVX A;  1CGF A;  1RMZ A;  2D1O A;  2ERP A;  2DDY A;  2USN A;  5D1T A;  2X3B A;  3P1V A;  1QUA A;  1JK3 A;  1R1H A;  5BOT A;  1XUC A;  1YQY A;  3L0T A;  1GKD A;  4AXQ A;  2OI0 A;  3DL1 A;  1G9K A;  1HFC A;  1ZVX A;  4GR3 A;  3L0V A;  1GE7 A;  830C A;  1BUV M;  3LK8 A;  2WO8 A;  1QJI A;  3HB2 P;  2MLS A;  1IAD A;  2YIG A;  3RTS A;  1B3D A;  5D1S A;  4PKT A;  4ILW D;  3LIK A;  1GO7 P;  1G05 A;  4DV8 A;  1UMS A;  2FV5 A;  2X3C A;  1BIW A;  5CUH A;  1ZS0 A;  2OY4 A;  3LEA A;  3O2X A;  1XFZ A;  4L19 A;  2PJT A;  4IN9 A;  1BKC A;  3F17 A;  3U1R A;  1C3I A;  1Q3A A;  4I35 A;  4GR8 A;  4IJO A;  5I3M A;  4XCT A;  1QIB A;  1K7Q A;  2JT5 A;  3LJT A;  1AST A;  1D7X A;  2QPJ A;  1A85 A;  4FVL A;  1A86 A;  3RTT A;  1JAP A;  1IAC A;  4H76 A;  1OO9 A;  3UVC A;  3AIG A;  4H3X A;  2YB9 A;  1SU3 A;  1JKY A;  1L6J A;  4CTH A;  2X7M A;  2JT6 A;  3VTG A;  3TS4 A;  2J83 A;  4PKU A;  4FU4 A;  966C A;  5I12 A;  2OW0 A;  1C8T A;  3LQB A;  2W15 A;  2JIH A;  3EDI A;  1RM8 A;  1KUK A;  3WV1 A;  3DPF A;  1MMQ A;  2JNP A;  2K9C A;  1J7N A;  4HMA A;  3HBV P;  1XUD A;  4H84 A;  1Y8J A;  3HY7 A;  1K7I A;  1KAP P;  3G5C A;  4ON1 A;  3HDA P;  3LGP A;  2E3X A;  2J0T A;  1PWV A;  3HYG A;  1AF0 A;  1EB6 A;  1CGL A;  2WOA A;  3VI1 A;  1C7K A;  1AKL A;  1MMB A;  2DW2 A;  3EDG A;  4A7B A;  1HV5 A;  3DNG A;  1ZXC A;  1GXD A;  3NX7 A;  1JAO A;  3G42 A;  1PWP A;  5LAB A;  1BQO A;  4IUW A;  1CXV A;  1FM1 A;  3Q2H A;  1WNI A;  5BOY A;  1CGE A;  3WV3 A;  2DW0 A;  1CK7 A;  4XM7 A;  1OMJ A;  1UTZ A;  5L7F A;  4L63 A;  4HX3 A;  3KEJ A;  1HFS A;  5I0L A;  3USN A;  4JP4 A;  1XFV A;  2Y6C A;  2ERO A;  3EHX A;  1I76 A;  1R54 A;  3I7I A;  1KUI A;  1IAB A;  3HDB A;  4WF6 A;  3MA2 A;  1JAQ A;  3KEK A;  2TCL A;  4PKV A;  4WK7 A;  2AIG P;  4DPE A;  2E2D A;  2OW9 A;  2CLT A;  3F18 A;  1USN A;  1ROS A;  3B92 A;  4PKS A;  3I7G A;  1OM8 A;  2MZH A;  456C A;  2OY2 A;  2SRT A;  3ZXH A;  1R1J A;  4L6T A;  5BPA A;  5D7W A;  1SRP A;  1UTT A;  3ZUK A;  1IAG A;  2K2G A;  1BKC E;  3OHL A;  3DSL A;  4WZV A;  2KRJ A;  1IAA A;  2DW1 A;  1BUD A;  1XFX A;  3LE9 A;  1QJJ A;  3LUM A;  4A3W A;  3KHI A;  2RJP A;  1PWW A;  4PKR A;  2OXW A;  3OHO A;  1I73 A; 
#chains in the Genus database with same CATH topology
 3ZVS A;  5D1U A;  2DDF A;  1DMT A;  3LJG A;  2D1N A;  1OS9 A;  4JPA A;  3B2Z A;  1FBL A;  2W0D A;  2MZI A;  4H2E A;  1YOU A;  3LIL A;  4GUY A;  4G9L A;  3EDZ A;  1ZTQ A;  1JAN A;  2W13 A;  2W14 A;  1XFW A;  5I2Z A;  1ATL A;  4G0D A;  3WV2 A;  1R1I A;  1YP1 A;  1OS2 A;  3KEC A;  3F16 A;  2O36 A;  4GF1 A;  1O0T A;  1JH1 A;  4JA1 A;  3HBU P;  3LMC A;  1UEA A;  1MMR A;  1OM7 A;  1HTD A;  3DPE A;  3F1A A;  5I4O A;  3Q2G A;  1IAE A;  4PKQ A;  3KME A;  1H71 P;  2V4B A;  2OXU A;  1G12 A;  1G4K A;  2OVZ A;  4QKZ A;  1S4B P;  1PWU A;  2OW2 A;  2XS3 A;  1BZS A;  4H30 A;  4AIG A;  1KUH A;  2W12 A;  1KUF A;  3DTI A;  3P24 A;  3AYK A;  3DWB A;  1GO8 P;  1MMP A;  2CKI A;  4XM6 A;  1OZ9 A;  3EWJ A;  2X3A A;  2A8H A;  3F19 A;  1JJ9 A;  2I47 A;  5CZM A;  1PWQ A;  1ND1 A;  1QIC A;  1O0Q A;  4WKI A;  1EUB A;  1Y93 A;  3AYU A;  1FLS A;  3GBO A;  3EDH A;  2O3E A;  2FV9 A;  1DTH A;  3B8Z A;  4DF9 A;  2N8R A;  4I03 A;  5B5P A;  3EHY A;  1ZXV A;  1BQQ M;  5JMY A;  2HU6 A;  1D8M A;  1GKC A;  1CQR A;  3K7N A;  2Y6D A;  1AYK A;  3V96 B;  3O64 A;  3TSK A;  2RJQ A;  1MNC A;  1BKC I;  4H49 A;  2OZR A;  1YCM A;  4EFS A;  1XUR A;  3N2U A;  3ELM A;  1R55 A;  1UMT A;  1K7G A;  2MLR A;  4J4M A;  1XM5 A;  1GE6 A;  4R3V A;  3TT4 A;  4GR0 A;  1SMP A;  1TVI A;  3HY9 A;  3LIR A;  1D5J A;  3KWV C;  3SHI A;  5D3C A;  2L0R A;  2WO9 A;  1SLM A;  1XFY A;  5D2B A;  1Y0V A;  4DD8 A;  5CXA A;  3LQ0 A;  3DTE A;  1KBC A;  2POJ A;  1HY7 A;  2OXZ A;  1SLN A;  5H8X A;  4WKE A;  1I1I P;  1HOV A;  4FXY P;  5B5O A;  1G49 A;  3CKI A;  2OW1 A;  3BA0 A;  4GWM A;  3KRY A;  4H82 A;  3K7L A;  2Z2D A;  3LKA A;  1EAK A;  2JSD A;  1B8Y A;  3LJZ A;  4GWN A;  3F15 A;  1BM6 A;  1JIZ A;  4AYK A;  1BSW A;  1ZP5 A;  3LUN A;  4H1Q A;  4PKW A;  4JQG A;  1GE5 A;  2AYK A;  3KMC A;  1CAQ A;  1JIW P;  4XBH A;  4AUO A;  1KUG A;  4GQL A;  4XM8 A;  1Z3J A;  4Q1L A;  3E8R A;  3TVC A;  2MZE A;  4FXQ A;  1OM6 A;  4JIJ A;  1XFU A;  2XS4 A;  5L79 A;  1D8F A;  1SAT A;  5I43 A;  1QIA A;  1CIZ A;  4ZR5 A;  2ERQ A;  3N2V A;  2OVX A;  1CGF A;  1RMZ A;  2D1O A;  2ERP A;  2DDY A;  2USN A;  5D1T A;  2X3B A;  3P1V A;  1QUA A;  1JK3 A;  1R1H A;  5BOT A;  1XUC A;  1YQY A;  3L0T A;  1GKD A;  4AXQ A;  2OI0 A;  3DL1 A;  1G9K A;  1HFC A;  1ZVX A;  4GR3 A;  2YUF A;  3L0V A;  1GE7 A;  830C A;  1BUV M;  3LK8 A;  2WO8 A;  1QJI A;  3HB2 P;  2MLS A;  1IAD A;  2YIG A;  3RTS A;  1B3D A;  5D1S A;  4PKT A;  4ILW D;  3LIK A;  1GO7 P;  1G05 A;  4DV8 A;  1UMS A;  2FV5 A;  2X3C A;  1BIW A;  5CUH A;  1ZS0 A;  2OY4 A;  3LEA A;  3O2X A;  1XFZ A;  4L19 A;  2PJT A;  4IN9 A;  1BKC A;  3F17 A;  3U1R A;  1C3I A;  1Q3A A;  4I35 A;  4GR8 A;  4IJO A;  5I3M A;  4XCT A;  1QIB A;  1K7Q A;  2JT5 A;  3LJT A;  1AST A;  1D7X A;  2QPJ A;  1A85 A;  4FVL A;  1A86 A;  3RTT A;  1JAP A;  1IAC A;  4H76 A;  1OO9 A;  3UVC A;  3AIG A;  4H3X A;  2YB9 A;  1SU3 A;  1JKY A;  1L6J A;  4CTH A;  2X7M A;  2JT6 A;  3VTG A;  3TS4 A;  2J83 A;  4PKU A;  4FU4 A;  966C A;  5I12 A;  2OW0 A;  1C8T A;  3LQB A;  2W15 A;  2JIH A;  3EDI A;  1RM8 A;  1KUK A;  3WV1 A;  3DPF A;  1MMQ A;  2JNP A;  2K9C A;  1J7N A;  4HMA A;  3HBV P;  1XUD A;  4H84 A;  1Y8J A;  3HY7 A;  1K7I A;  1KAP P;  3G5C A;  4ON1 A;  3HDA P;  3LGP A;  2E3X A;  2J0T A;  1PWV A;  3HYG A;  1AF0 A;  1EB6 A;  1CGL A;  2WOA A;  3VI1 A;  1C7K A;  1AKL A;  1MMB A;  2DW2 A;  3EDG A;  4A7B A;  1HV5 A;  3DNG A;  1ZXC A;  1GXD A;  3NX7 A;  1JAO A;  3G42 A;  1PWP A;  5LAB A;  1BQO A;  4IUW A;  1CXV A;  1FM1 A;  3Q2H A;  1WNI A;  5BOY A;  1CGE A;  3WV3 A;  2DW0 A;  1CK7 A;  4XM7 A;  1OMJ A;  1UTZ A;  5L7F A;  4L63 A;  4HX3 A;  3KEJ A;  1HFS A;  5I0L A;  3USN A;  4JP4 A;  1XFV A;  2Y6C A;  2ERO A;  3EHX A;  1I76 A;  1R54 A;  3I7I A;  1KUI A;  1IAB A;  3HDB A;  4WF6 A;  3DTK A;  3MA2 A;  1JAQ A;  3KEK A;  2TCL A;  4PKV A;  4WK7 A;  2AIG P;  4DPE A;  2E2D A;  2OW9 A;  2CLT A;  3F18 A;  1USN A;  1ROS A;  3B92 A;  4PKS A;  3I7G A;  1OM8 A;  1XAX A;  2MZH A;  4L7A A;  456C A;  2OY2 A;  2SRT A;  3ZXH A;  1R1J A;  4L6T A;  5BPA A;  5D7W A;  1SRP A;  1UTT A;  3ZUK A;  1IAG A;  2K2G A;  1BKC E;  3OHL A;  3DSL A;  4WZV A;  2KRJ A;  1IAA A;  2DW1 A;  1BUD A;  1XFX A;  3LE9 A;  1QJJ A;  3LUM A;  4A3W A;  3KHI A;  2RJP A;  1PWW A;  4PKR A;  2OXW A;  3OHO A;  1I73 A; 
#chains in the Genus database with same CATH homology
 3ZVS A;  5D1U A;  2DDF A;  1DMT A;  3LJG A;  2D1N A;  1OS9 A;  4JPA A;  3B2Z A;  1FBL A;  2W0D A;  2MZI A;  4H2E A;  1YOU A;  3LIL A;  4GUY A;  4G9L A;  3EDZ A;  1ZTQ A;  1JAN A;  2W13 A;  2W14 A;  1XFW A;  5I2Z A;  1ATL A;  4G0D A;  3WV2 A;  1R1I A;  1YP1 A;  1OS2 A;  3KEC A;  3F16 A;  2O36 A;  4GF1 A;  1O0T A;  1JH1 A;  4JA1 A;  3HBU P;  3LMC A;  1UEA A;  1MMR A;  1OM7 A;  1HTD A;  3DPE A;  3F1A A;  5I4O A;  3Q2G A;  1IAE A;  4PKQ A;  3KME A;  1H71 P;  2V4B A;  2OXU A;  1G12 A;  1G4K A;  2OVZ A;  4QKZ A;  1S4B P;  1PWU A;  2OW2 A;  2XS3 A;  1BZS A;  4H30 A;  4AIG A;  1KUH A;  2W12 A;  1KUF A;  3DTI A;  3P24 A;  3AYK A;  3DWB A;  1GO8 P;  1MMP A;  2CKI A;  4XM6 A;  3EWJ A;  2X3A A;  2A8H A;  3F19 A;  1JJ9 A;  2I47 A;  5CZM A;  1PWQ A;  1ND1 A;  1QIC A;  1O0Q A;  4WKI A;  1EUB A;  1Y93 A;  3AYU A;  1FLS A;  3GBO A;  3EDH A;  2O3E A;  2FV9 A;  1DTH A;  3B8Z A;  4DF9 A;  2N8R A;  4I03 A;  5B5P A;  3EHY A;  1ZXV A;  1BQQ M;  5JMY A;  2HU6 A;  1D8M A;  1GKC A;  1CQR A;  3K7N A;  2Y6D A;  1AYK A;  3V96 B;  3O64 A;  3TSK A;  2RJQ A;  1MNC A;  1BKC I;  4H49 A;  2OZR A;  1YCM A;  4EFS A;  1XUR A;  3N2U A;  3ELM A;  1R55 A;  1UMT A;  1K7G A;  2MLR A;  4J4M A;  1GE6 A;  4R3V A;  3TT4 A;  4GR0 A;  1SMP A;  3HY9 A;  3LIR A;  1D5J A;  3KWV C;  3SHI A;  5D3C A;  2L0R A;  2WO9 A;  1SLM A;  1XFY A;  5D2B A;  1Y0V A;  4DD8 A;  5CXA A;  3LQ0 A;  3DTE A;  1KBC A;  2POJ A;  1HY7 A;  2OXZ A;  1SLN A;  5H8X A;  4WKE A;  1I1I P;  1HOV A;  4FXY P;  5B5O A;  1G49 A;  3CKI A;  2OW1 A;  3BA0 A;  4GWM A;  3KRY A;  4H82 A;  3K7L A;  2Z2D A;  3LKA A;  1EAK A;  2JSD A;  1B8Y A;  3LJZ A;  4GWN A;  3F15 A;  1BM6 A;  1JIZ A;  4AYK A;  1BSW A;  1ZP5 A;  3LUN A;  4H1Q A;  4PKW A;  4JQG A;  1GE5 A;  2AYK A;  3KMC A;  1CAQ A;  1JIW P;  4XBH A;  4AUO A;  1KUG A;  4GQL A;  4XM8 A;  1Z3J A;  4Q1L A;  3E8R A;  3TVC A;  2MZE A;  4FXQ A;  1OM6 A;  4JIJ A;  1XFU A;  2XS4 A;  5L79 A;  1D8F A;  1SAT A;  5I43 A;  1QIA A;  1CIZ A;  4ZR5 A;  2ERQ A;  3N2V A;  2OVX A;  1CGF A;  1RMZ A;  2D1O A;  2ERP A;  2DDY A;  2USN A;  5D1T A;  2X3B A;  3P1V A;  1QUA A;  1JK3 A;  1R1H A;  5BOT A;  1XUC A;  1YQY A;  3L0T A;  1GKD A;  4AXQ A;  2OI0 A;  3DL1 A;  1G9K A;  1HFC A;  1ZVX A;  4GR3 A;  2YUF A;  3L0V A;  1GE7 A;  830C A;  1BUV M;  3LK8 A;  2WO8 A;  1QJI A;  3HB2 P;  2MLS A;  1IAD A;  2YIG A;  3RTS A;  1B3D A;  5D1S A;  4PKT A;  4ILW D;  3LIK A;  1GO7 P;  1G05 A;  4DV8 A;  1UMS A;  2FV5 A;  2X3C A;  1BIW A;  5CUH A;  1ZS0 A;  2OY4 A;  3LEA A;  3O2X A;  1XFZ A;  4L19 A;  2PJT A;  4IN9 A;  1BKC A;  3F17 A;  3U1R A;  1C3I A;  1Q3A A;  4I35 A;  4GR8 A;  4IJO A;  5I3M A;  4XCT A;  1QIB A;  1K7Q A;  2JT5 A;  3LJT A;  1AST A;  1D7X A;  2QPJ A;  1A85 A;  4FVL A;  1A86 A;  3RTT A;  1JAP A;  1IAC A;  4H76 A;  1OO9 A;  3UVC A;  3AIG A;  4H3X A;  2YB9 A;  1SU3 A;  1JKY A;  1L6J A;  4CTH A;  2X7M A;  2JT6 A;  3VTG A;  3TS4 A;  2J83 A;  4PKU A;  4FU4 A;  966C A;  5I12 A;  2OW0 A;  1C8T A;  3LQB A;  2W15 A;  2JIH A;  3EDI A;  1RM8 A;  1KUK A;  3WV1 A;  3DPF A;  1MMQ A;  2JNP A;  2K9C A;  1J7N A;  4HMA A;  3HBV P;  1XUD A;  4H84 A;  1Y8J A;  3HY7 A;  1K7I A;  1KAP P;  3G5C A;  4ON1 A;  3HDA P;  3LGP A;  2E3X A;  2J0T A;  1PWV A;  3HYG A;  1AF0 A;  1EB6 A;  1CGL A;  2WOA A;  3VI1 A;  1C7K A;  1AKL A;  1MMB A;  2DW2 A;  3EDG A;  4A7B A;  1HV5 A;  3DNG A;  1ZXC A;  1GXD A;  3NX7 A;  1JAO A;  3G42 A;  1PWP A;  5LAB A;  1BQO A;  4IUW A;  1CXV A;  1FM1 A;  3Q2H A;  1WNI A;  5BOY A;  1CGE A;  3WV3 A;  2DW0 A;  1CK7 A;  4XM7 A;  1OMJ A;  1UTZ A;  5L7F A;  4L63 A;  4HX3 A;  3KEJ A;  1HFS A;  5I0L A;  3USN A;  4JP4 A;  1XFV A;  2Y6C A;  2ERO A;  3EHX A;  1I76 A;  1R54 A;  3I7I A;  1KUI A;  1IAB A;  3HDB A;  4WF6 A;  3DTK A;  3MA2 A;  1JAQ A;  3KEK A;  2TCL A;  4PKV A;  4WK7 A;  2AIG P;  4DPE A;  2E2D A;  2OW9 A;  2CLT A;  3F18 A;  1USN A;  1ROS A;  3B92 A;  4PKS A;  3I7G A;  1OM8 A;  2MZH A;  4L7A A;  456C A;  2OY2 A;  2SRT A;  3ZXH A;  1R1J A;  4L6T A;  5BPA A;  5D7W A;  1SRP A;  1UTT A;  3ZUK A;  1IAG A;  2K2G A;  1BKC E;  3OHL A;  3DSL A;  4WZV A;  2KRJ A;  1IAA A;  2DW1 A;  1BUD A;  1XFX A;  3LE9 A;  1QJJ A;  3LUM A;  4A3W A;  3KHI A;  2RJP A;  1PWW A;  4PKR A;  2OXW A;  3OHO A;  1I73 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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