2WTTA

Structure of the human p73 tetramerization domain (crystal form ii)
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
42
structure length
42
Chain Sequence
EDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Evolution of P53, P63, and P73: Implication for Heterotetramer Formation.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords TUMOR PROTEIN P73
total genus 10
structure length 42
sequence length 42
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
ec nomenclature
pdb deposition date 2009-09-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.170.10 Few Secondary Structures Irregular p53, subunit A p53-like tetramerisation domain 2wttA00
1SAKA 1OLHA 1SAEA 2WTTA 5HOBA 2KBYA 2WQIA 1SALA 3ZY1A 4A9ZA 1SAFA 2MW4A 1OLGA 3SAKA 5HOCA
chains in the Genus database with same CATH superfamily
1SAKA 1OLHA 1SAEA 2WTTA 5HOBA 2KBYA 2WQIA 1SALA 3ZY1A 4A9ZA 1SAFA 2MW4A 1OLGA 3SAKA 5HOCA
chains in the Genus database with same CATH topology
1SAKA 1OLHA 1SAEA 2WTTA 5HOBA 2KBYA 2WQIA 1SALA 3ZY1A 4A9ZA 1SAFA 2MW4A 1OLGA 3SAKA 5HOCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SAK A;  1OLH A;  1SAE A;  2WTT A;  5HOB A;  2KBY A;  2WQI A;  1SAL A;  3ZY1 A;  4A9Z A;  1SAF A;  2MW4 A;  1OLG A;  3SAK A;  5HOC A; 
#chains in the Genus database with same CATH topology
 1SAK A;  1OLH A;  1SAE A;  2WTT A;  5HOB A;  2KBY A;  2WQI A;  1SAL A;  3ZY1 A;  4A9Z A;  1SAF A;  2MW4 A;  1OLG A;  3SAK A;  5HOC A; 
#chains in the Genus database with same CATH homology
 1SAK A;  1OLH A;  1SAE A;  2WTT A;  5HOB A;  2KBY A;  2WQI A;  1SAL A;  3ZY1 A;  4A9Z A;  1SAF A;  2MW4 A;  1OLG A;  3SAK A;  5HOC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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