The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
46
|
sequence length |
174
|
structure length |
160
|
Chain Sequence |
RGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTRALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVIVAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYSKRLGTEKEVEVIGGADKYHSVCRLCYFK
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Comparative Active-Site Mutation Study of Human and Caenorhabditis Elegans Thymidine Kinase 1.
pubmed doi rcsb |
| molecule keywords |
THYMIDINE KINASE, CYTOSOLIC
|
| source organism |
Homo sapiens
|
| molecule tags |
Transferase
|
| total genus |
46
|
| structure length |
160
|
| sequence length |
174
|
| chains with identical sequence |
B, C, D, E, F, G, H
|
| ec nomenclature |
ec
2.7.1.21: Thymidine kinase. |
| pdb deposition date | 2009-10-17 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00265 | TK | Thymidine kinase |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | Wheat Germ Agglutinin (Isolectin 2); domain 1 | Wheat Germ Agglutinin (Isolectin 2); domain 1 | ||
| Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | P-loop containing nucleotide triphosphate hydrolases |
