2WXUA

Clostridium perfringens alpha-toxin strain nctc8237 mutant t74i
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
370
structure length
361
Chain Sequence
WDGKIDGTGTHAMIVTQGVSILENDLSKNEPESVRKNLEILKENMHELQLGSTYPDYDKNAYDLYQDHFWDPDIWYLAYSIPDTGESQIRKFSALARYEWQRGNYKQATFYLGEAMHYFGDIDTPYHPANVTAVDSAGHVKFETFAEERKEQYKINTAGCKTNEAFYTDILKNKDFNAWSKEYARGFAKTGKSIYYSHASMSHSWDDWDYAAKVTLANSQKGTAGYIYRFLHDVSEGNDPSVGKNVKELVAYISTSGEKDAGTDDYMYFGIKTKDGKTQEWEMDNPGNDFMTGSKDTYTFKLKDENLKIDDIQNMWIRKRKYTAFPDAYKPENIKIIANGKVVVDKDINEWISGNSTYNIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Comparison of a Nontoxic Variant of Clostridium Perfringens [Alpha]-Toxin with the Toxic Wild-Type Strain
pubmed doi rcsb
molecule tags Hydrolase
source organism Clostridium perfringens
molecule keywords PHOSPHOLIPASE C
total genus 139
structure length 361
sequence length 370
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 2009-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
A PF01477 PLAT PLAT/LH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 2wxuA01
2.60.60.20 Mainly Beta Sandwich Lipoxygenase-1 PLAT/LH2 domain 2wxuA02
1LOXA 3BNEA 1BU8A 5FBBA 3BNDA 1GYGA 4DJ4A 5FBCA 3PZWA 3V92A 2HUCA 2IUJA 4CXVA 5FBFA 4WHAA 1N8QA 1ETHA 1QMDA 1P5XA 4CXOA 1FGQA 1HU9A 2FFZA 3W52A 1NO3A 1HPLA 2FNQA 1ROVA 1KHOA 1P6DA 4CXPA 4WFOA 1IK3A 5FB9A 3V99A 1FGOA 4JDGA 1QM6A 1RP1A 5FBDA 1FGTA 1FGMA 1FGRA 2FGNA 3FG1A 1Y4KA 3FG3A 2PVSA 1LNHA 5FBAA 1P6EA 5FBGA 3FG4A 2OXEA 2WY6A 5EEOA 1W52X 1YGEA 2SBLA 3CWZB 1RRLA 1F8NA 3BNCA 1CA1A 1OLPA 1AK0A 2IUKA 2P0MA 1N8SA 4QWTA 2PPLA 3BNBA 2WXTA 2WXUA 4CWMA 1JNQA 4NREA 3V98A 1RRHA 1AH7A 3O8YA 1LPBB 1GPLA 1LPAB 3SNGA 3VF1A
chains in the Genus database with same CATH superfamily
3U6GA 1LOXA 3BNEA 1BU8A 2LGEA 5FBBA 3BNDA 1GYGA 4DJ4A 5FBCA 3PZWA 3V92A 2HUCA 4QEYA 2IUJA 4CXVA 2XHHA 5FBFA 4WHAA 1N8QA 1ETHA 2KXVA 2LRGA 1QMDA 1P5XA 2QNGA 4CXOA 1FGQA 1HU9A 2FFZA 3W52A 2KXTA 1NO3A 1HPLA 2FNQA 1ROVA 1KHOA 1P6DA 4CXPA 4WFOA 2QZ7A 1IK3A 5FB9A 3V99A 1FGOA 4JDGA 1QM6A 1RP1A 5FBDA 1FGTA 1FGMA 1FGRA 2FGNA 3IBZA 2XFEA 3FG1A 1Y4KA 2XFDA 3FG3A 2PVSA 1LNHA 5FBAA 1P6EA 5FBGA 3FG4A 2LG7A 2OXEA 2WY6A 5EEOA 2XHJA 1W52X 1YGEA 2SBLA 3CWZB 1RRLA 1F8NA 3BNCA 1CA1A 1OLPA 1AK0A 2IUKA 2P0MA 1N8SA 4QWTA 2PPLA 3BNBA 2WXTA 2WXUA 4CWMA 1JNQA 4NREA 3V98A 1RRHA 1AH7A 3O8YA 1LPBB 1GPLA 1LPAB 3SNGA 3VF1A
chains in the Genus database with same CATH topology
1LOXA 3BNEA 1BU8A 5FBBA 3BNDA 1GYGA 4DJ4A 5FBCA 3PZWA 3V92A 2HUCA 2IUJA 4CXVA 5FBFA 4WHAA 1N8QA 1ETHA 1QMDA 1P5XA 4CXOA 1FGQA 1HU9A 2FFZA 3W52A 1NO3A 1HPLA 2FNQA 1ROVA 1KHOA 1P6DA 4CXPA 4WFOA 1IK3A 5FB9A 3V99A 1FGOA 4JDGA 1QM6A 1RP1A 5FBDA 1FGTA 1FGMA 1FGRA 2FGNA 3FG1A 1Y4KA 3FG3A 2PVSA 1LNHA 5FBAA 1P6EA 5FBGA 3FG4A 2OXEA 2WY6A 5EEOA 1W52X 1YGEA 2SBLA 3CWZB 1RRLA 1F8NA 3BNCA 1CA1A 1OLPA 1AK0A 2IUKA 2P0MA 1N8SA 4QWTA 2PPLA 3BNBA 2WXTA 2WXUA 4CWMA 1JNQA 4NREA 3V98A 1RRHA 1AH7A 3O8YA 1LPBB 1GPLA 1LPAB 3SNGA 3VF1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LOX A;  3BNE A;  1BU8 A;  5FBB A;  3BND A;  1GYG A;  4DJ4 A;  5FBC A;  3PZW A;  3V92 A;  2HUC A;  2IUJ A;  4CXV A;  5FBF A;  4WHA A;  1N8Q A;  1ETH A;  1QMD A;  1P5X A;  4CXO A;  1FGQ A;  1HU9 A;  2FFZ A;  3W52 A;  1NO3 A;  1HPL A;  2FNQ A;  1ROV A;  1KHO A;  1P6D A;  4CXP A;  4WFO A;  1IK3 A;  5FB9 A;  3V99 A;  1FGO A;  4JDG A;  1QM6 A;  1RP1 A;  5FBD A;  1FGT A;  1FGM A;  1FGR A;  2FGN A;  3FG1 A;  1Y4K A;  3FG3 A;  2PVS A;  1LNH A;  5FBA A;  1P6E A;  5FBG A;  3FG4 A;  2OXE A;  2WY6 A;  5EEO A;  1W52 X;  1YGE A;  2SBL A;  3CWZ B;  1RRL A;  1F8N A;  3BNC A;  1CA1 A;  1OLP A;  1AK0 A;  2IUK A;  2P0M A;  1N8S A;  4QWT A;  2PPL A;  3BNB A;  2WXT A;  2WXU A;  4CWM A;  1JNQ A;  4NRE A;  3V98 A;  1RRH A;  1AH7 A;  3O8Y A;  1LPB B;  1GPL A;  1LPA B;  3SNG A;  3VF1 A; 
#chains in the Genus database with same CATH topology
 3U6G A;  1LOX A;  3BNE A;  1BU8 A;  2LGE A;  5FBB A;  3BND A;  1GYG A;  4DJ4 A;  5FBC A;  3PZW A;  3V92 A;  2HUC A;  4QEY A;  2IUJ A;  4CXV A;  2XHH A;  5FBF A;  4WHA A;  1N8Q A;  1ETH A;  2KXV A;  2LRG A;  1QMD A;  1P5X A;  2QNG A;  4CXO A;  1FGQ A;  1HU9 A;  2FFZ A;  3W52 A;  2KXT A;  1NO3 A;  1HPL A;  2FNQ A;  1ROV A;  1KHO A;  1P6D A;  4CXP A;  4WFO A;  2QZ7 A;  1IK3 A;  5FB9 A;  3V99 A;  1FGO A;  4JDG A;  1QM6 A;  1RP1 A;  5FBD A;  1FGT A;  1FGM A;  1FGR A;  2FGN A;  3IBZ A;  2XFE A;  3FG1 A;  1Y4K A;  2XFD A;  3FG3 A;  2PVS A;  1LNH A;  5FBA A;  1P6E A;  5FBG A;  3FG4 A;  2LG7 A;  2OXE A;  2WY6 A;  5EEO A;  2XHJ A;  1W52 X;  1YGE A;  2SBL A;  3CWZ B;  1RRL A;  1F8N A;  3BNC A;  1CA1 A;  1OLP A;  1AK0 A;  2IUK A;  2P0M A;  1N8S A;  4QWT A;  2PPL A;  3BNB A;  2WXT A;  2WXU A;  4CWM A;  1JNQ A;  4NRE A;  3V98 A;  1RRH A;  1AH7 A;  3O8Y A;  1LPB B;  1GPL A;  1LPA B;  3SNG A;  3VF1 A; 
#chains in the Genus database with same CATH homology
 1LOX A;  3BNE A;  1BU8 A;  5FBB A;  3BND A;  1GYG A;  4DJ4 A;  5FBC A;  3PZW A;  3V92 A;  2HUC A;  2IUJ A;  4CXV A;  5FBF A;  4WHA A;  1N8Q A;  1ETH A;  1QMD A;  1P5X A;  4CXO A;  1FGQ A;  1HU9 A;  2FFZ A;  3W52 A;  1NO3 A;  1HPL A;  2FNQ A;  1ROV A;  1KHO A;  1P6D A;  4CXP A;  4WFO A;  1IK3 A;  5FB9 A;  3V99 A;  1FGO A;  4JDG A;  1QM6 A;  1RP1 A;  5FBD A;  1FGT A;  1FGM A;  1FGR A;  2FGN A;  3FG1 A;  1Y4K A;  3FG3 A;  2PVS A;  1LNH A;  5FBA A;  1P6E A;  5FBG A;  3FG4 A;  2OXE A;  2WY6 A;  5EEO A;  1W52 X;  1YGE A;  2SBL A;  3CWZ B;  1RRL A;  1F8N A;  3BNC A;  1CA1 A;  1OLP A;  1AK0 A;  2IUK A;  2P0M A;  1N8S A;  4QWT A;  2PPL A;  3BNB A;  2WXT A;  2WXU A;  4CWM A;  1JNQ A;  4NRE A;  3V98 A;  1RRH A;  1AH7 A;  3O8Y A;  1LPB B;  1GPL A;  1LPA B;  3SNG A;  3VF1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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