2WYBA

The quorum quenching n-acyl homoserine lactone acylase pvdq with a covalently bound dodecanoic acid
Total Genus 53
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
164
structure length
164
Chain Sequence
TGLAADIRWTAYGVPHIRAKDERGLGYGIGYAYARDNACLLAEEIVTARGERARYFGSEGKSSAELDNLPSDIFYAWLNQPEALQAFWQAQTPAVRQLLEGYAAGFNRFLREADGKTTSCLGQPWLRAIATDDLLRLTRRLLVEGGVGQFADALVAAAPPGAEK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title The Quorum-Quenching N-Acyl Homoserine Lactone Acylase Pvdq is an Ntn-Hydrolase with an Unusual Substrate-Binding Pocket
pubmed doi rcsb
molecule tags Hydrolase
source organism Pseudomonas aeruginosa
molecule keywords ACYL-HOMOSERINE LACTONE ACYLASE PVDQ SUBUNIT ALPHA
total genus 53
structure length 164
sequence length 164
ec nomenclature ec 3.5.1.97: Acyl-homoserine-lactone acylase.
pdb deposition date 2009-11-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.439.10 Mainly Alpha Orthogonal Bundle Penicillin Amidohydrolase; domain 1 Penicillin Amidohydrolase, domain 1 2wybA00
1PNMA 2WYBA 3SRBA 1AI7A 2WYDA 4E55A 2AE3A 1K5QA 4PELA 3SRCA 4WKVA 4WKUA 3SRAA 1AI4A 1GHDA 4PEMA 4BTHA 1KECA 1PNLA 1AJQA 1E3AA 3K3WA 3L91A 1AI5A 1GM8A 1CP9A 4YFBA 4YFAA 4K2FA 4WKSA 1JW0A 4WKTA 3JTRA 1K5SA 3L94A 4HSTA 1FXHA 1GK1A 1JX9A 3S8RA 3JTQA 1GM9A 1GK0A 4HSRA 1PNKA 1FXVA 4M1JA 1GK9A 1H2GA 1K7DA 2ADVA 2WYEA 4E57A 1OR0A 1FM2A 1JVZA 1GKFA 4K2GA 1AJNA 1GM7A 2AE5A 4E56A 1AI6A 1AJPA 2WYCA 4YF9A 2AE4A 1KEHA 3ML0A
chains in the Genus database with same CATH superfamily
1PNMA 2WYBA 3SRBA 1AI7A 2WYDA 4E55A 2AE3A 1K5QA 4PELA 3SRCA 4WKVA 4WKUA 3SRAA 1AI4A 1GHDA 4PEMA 4BTHA 1KECA 1PNLA 1AJQA 1E3AA 3K3WA 3L91A 1AI5A 1GM8A 1CP9A 4YFBA 4YFAA 4K2FA 4WKSA 1JW0A 4WKTA 3JTRA 1K5SA 3L94A 4HSTA 1FXHA 1GK1A 1JX9A 3S8RA 3FGTA 3JTQA 1GM9A 1GK0A 4HSRA 1PNKA 1FXVA 4M1JA 1GK9A 1H2GA 1K7DA 2ADVA 2WYEA 4BWCA 4E57A 1OR0A 3FGRA 1FM2A 1JVZA 1GKFA 4K2GA 1AJNA 1GM7A 2AE5A 4E56A 1AI6A 1AJPA 2WYCA 4YF9A 2AE4A 1KEHA 3ML0A
chains in the Genus database with same CATH topology
1PNMA 2WYBA 3SRBA 1AI7A 2WYDA 4E55A 2AE3A 1K5QA 4PELA 3SRCA 4WKVA 4WKUA 3SRAA 1AI4A 1GHDA 4PEMA 4BTHA 1KECA 1PNLA 1AJQA 1E3AA 3K3WA 3L91A 1AI5A 1GM8A 1CP9A 4YFBA 4YFAA 4K2FA 4WKSA 1JW0A 4WKTA 3JTRA 1K5SA 3L94A 4HSTA 1FXHA 1GK1A 1JX9A 3S8RA 3JTQA 1GM9A 1GK0A 4HSRA 1PNKA 1FXVA 4M1JA 1GK9A 1H2GA 1K7DA 2ADVA 2WYEA 4E57A 1OR0A 1FM2A 1JVZA 1GKFA 4K2GA 1AJNA 1GM7A 2AE5A 4E56A 1AI6A 1AJPA 2WYCA 4YF9A 2AE4A 1KEHA 3ML0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PNM A;  2WYB A;  3SRB A;  1AI7 A;  2WYD A;  4E55 A;  2AE3 A;  1K5Q A;  4PEL A;  3SRC A;  4WKV A;  4WKU A;  3SRA A;  1AI4 A;  1GHD A;  4PEM A;  4BTH A;  1KEC A;  1PNL A;  1AJQ A;  1E3A A;  3K3W A;  3L91 A;  1AI5 A;  1GM8 A;  1CP9 A;  4YFB A;  4YFA A;  4K2F A;  4WKS A;  1JW0 A;  4WKT A;  3JTR A;  1K5S A;  3L94 A;  4HST A;  1FXH A;  1GK1 A;  1JX9 A;  3S8R A;  3JTQ A;  1GM9 A;  1GK0 A;  4HSR A;  1PNK A;  1FXV A;  4M1J A;  1GK9 A;  1H2G A;  1K7D A;  2ADV A;  2WYE A;  4E57 A;  1OR0 A;  1FM2 A;  1JVZ A;  1GKF A;  4K2G A;  1AJN A;  1GM7 A;  2AE5 A;  4E56 A;  1AI6 A;  1AJP A;  2WYC A;  4YF9 A;  2AE4 A;  1KEH A;  3ML0 A; 
#chains in the Genus database with same CATH topology
 1PNM A;  2WYB A;  3SRB A;  1AI7 A;  2WYD A;  4E55 A;  2AE3 A;  1K5Q A;  4PEL A;  3SRC A;  4WKV A;  4WKU A;  3SRA A;  1AI4 A;  1GHD A;  4PEM A;  4BTH A;  1KEC A;  1PNL A;  1AJQ A;  1E3A A;  3K3W A;  3L91 A;  1AI5 A;  1GM8 A;  1CP9 A;  4YFB A;  4YFA A;  4K2F A;  4WKS A;  1JW0 A;  4WKT A;  3JTR A;  1K5S A;  3L94 A;  4HST A;  1FXH A;  1GK1 A;  1JX9 A;  3S8R A;  3FGT A;  3JTQ A;  1GM9 A;  1GK0 A;  4HSR A;  1PNK A;  1FXV A;  4M1J A;  1GK9 A;  1H2G A;  1K7D A;  2ADV A;  2WYE A;  4BWC A;  4E57 A;  1OR0 A;  3FGR A;  1FM2 A;  1JVZ A;  1GKF A;  4K2G A;  1AJN A;  1GM7 A;  2AE5 A;  4E56 A;  1AI6 A;  1AJP A;  2WYC A;  4YF9 A;  2AE4 A;  1KEH A;  3ML0 A; 
#chains in the Genus database with same CATH homology
 1PNM A;  2WYB A;  3SRB A;  1AI7 A;  2WYD A;  4E55 A;  2AE3 A;  1K5Q A;  4PEL A;  3SRC A;  4WKV A;  4WKU A;  3SRA A;  1AI4 A;  1GHD A;  4PEM A;  4BTH A;  1KEC A;  1PNL A;  1AJQ A;  1E3A A;  3K3W A;  3L91 A;  1AI5 A;  1GM8 A;  1CP9 A;  4YFB A;  4YFA A;  4K2F A;  4WKS A;  1JW0 A;  4WKT A;  3JTR A;  1K5S A;  3L94 A;  4HST A;  1FXH A;  1GK1 A;  1JX9 A;  3S8R A;  3JTQ A;  1GM9 A;  1GK0 A;  4HSR A;  1PNK A;  1FXV A;  4M1J A;  1GK9 A;  1H2G A;  1K7D A;  2ADV A;  2WYE A;  4E57 A;  1OR0 A;  1FM2 A;  1JVZ A;  1GKF A;  4K2G A;  1AJN A;  1GM7 A;  2AE5 A;  4E56 A;  1AI6 A;  1AJP A;  2WYC A;  4YF9 A;  2AE4 A;  1KEH A;  3ML0 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...