2WZKA

Structure of the cul5 n-terminal domain at 2.05a resolution.
Total Genus 152
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
152
sequence length
377
structure length
369
Chain Sequence
SLQFEDKWDFMHPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGSSKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEVTLLGKMEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYREQLDTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKAENL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords CULLIN-5
publication title Molecular Architecture of the Ankyrin Socs Box Family of Cul5-Dependent E3 Ubiquitin Ligases
pubmed doi rcsb
source organism Mus musculus
molecule tags Protein binding
total genus 152
structure length 369
sequence length 377
ec nomenclature
pdb deposition date 2009-11-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 2wzkA01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 2wzkA02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 2wzkA03
4JGHD 4WQOD 1LDKA 1U6GA 1LDJA 1LDKB 4HXIB 4N9F3 3RTRA 4EOZB 2WZKA 3DPLC 4P5OA 4APFB 4F52A 4A64A 4AP2B 3DQVC
chains in the Genus database with same CATH superfamily
2PFVA 4HXIB 4F52A 4A64A 4NUVA 4JGHD 1U6GA 1LDJA 3BQKA 3DPLC 4P5OA 3RRCA 2XU0A 3BQLA 3CPZA 1LDKA 4YFSA 2Y8DA 3CMLA 4NUUA 4AP2B 3DQVC 3RTRA 4WQOD 1LDKB 4N9F3 5F3JA 4EOZB 2WZKA 3BQIA 2B1EA 2WAUA 4APFB
chains in the Genus database with same CATH topology
4JGHD 4WQOD 1LDKA 1U6GA 1LDJA 1LDKB 4HXIB 4N9F3 3RTRA 4EOZB 2WZKA 3DPLC 4P5OA 4APFB 4F52A 4A64A 4AP2B 3DQVC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JGH D;  4WQO D;  1LDK A;  1U6G A;  1LDJ A;  1LDK B;  4HXI B;  4N9F 3;  3RTR A;  4EOZ B;  2WZK A;  3DPL C;  4P5O A;  4APF B;  4F52 A;  4A64 A;  4AP2 B;  3DQV C; 
#chains in the Genus database with same CATH topology
 2PFV A;  4HXI B;  4F52 A;  4A64 A;  4NUV A;  4JGH D;  1U6G A;  1LDJ A;  3BQK A;  3DPL C;  4P5O A;  3RRC A;  2XU0 A;  3BQL A;  3CPZ A;  1LDK A;  4YFS A;  2Y8D A;  3CML A;  4NUU A;  4AP2 B;  3DQV C;  3RTR A;  4WQO D;  1LDK B;  4N9F 3;  5F3J A;  4EOZ B;  2WZK A;  3BQI A;  2B1E A;  2WAU A;  4APF B; 
#chains in the Genus database with same CATH homology
 4JGH D;  4WQO D;  1LDK A;  1U6G A;  1LDJ A;  1LDK B;  4HXI B;  4N9F 3;  3RTR A;  4EOZ B;  2WZK A;  3DPL C;  4P5O A;  4APF B;  4F52 A;  4A64 A;  4AP2 B;  3DQV C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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