2X00D

Crystal structure of a-achbp in complex with gymnodimine a
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
212
structure length
212
Chain Sequence
DDDLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Determinants in Phycotoxins and Achbp Conferring High Affinity Binding and Nicotinic Achr Antagonism.
pubmed doi rcsb
molecule tags Receptor
source organism Aplysia californica
molecule keywords SOLUBLE ACETYLCHOLINE RECEPTOR
total genus 54
structure length 212
sequence length 212
ec nomenclature
pdb deposition date 2009-12-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 2x00D00
4X5TA 3UQ4A 5KE4A 2QC1B 4HQPA 2XZ6A 4TWFA 2X00D 3WTIA 5J5HA 2BYSA 2XQAA 3U8MA 3U8LA 4ILBA 2WNJA 2PGZA 5AFMB 4COFA 2XYSA 2WZYA 3UU3A 3ZDGA 4BQTA 2BG9B 4AFGA 2YOEA 4QH5A 3WTLA 2Y7YA 5AFLA 3P4WA 3LSVA 2BR7A 4TWDA 4EZ1A 4ZRUA 3U8JA 2C9TA 3WIPA 2XQ6A 4TWHA 3T4MA 3RQUA 4LMLA 4PIRA 2YMDA 5TVCA 4D01A 5FJVA 4FRRA 4UY2A 4A98A 4UXUA 2UZ6A 4BFQA 3EHZA 4ZK1A 3GUAA 5BP0A 2YN6A 4LMKA 2Y57A 3TLVA 2W8GA 5AINA 4ZJSA 2YKSA 4NPPA 5HEGA 5HEJA 4QABA 3RI5A 3TLUA 3UU4A 3C84A 5AFJA 3SIOA 4HFDA 2ZJVA 3SQ9A 2X00A 3UUBA 2XQ8A 3TLTA 4QACA 3UQ7A 4HFIA 4QH1A 5AFMA 5AFNA 1UW6A 3WTMA 4TNVA 4UM3P 3UU8A 2BYQA 5J5GA 2XNTA 4UM1A 2Y58A 2BG9A 4QAAA 1UV6A 5HEOA 3WTNA 2WNLA 3PEOA 5BW2A 2BR8A 2PH9A 5SYOA 4Z91A 2XYTA 4ZZCA 2BJ0A 4IREA 5L4HA 4IL4A 5J5IA 2BG9C 4HFCA 4Z90A 3C79A 3RQWA 3WTHA 4UM3S 1UX2A 3RIFA 2BYPA 5J0ZA 3WTOA 4ZK4A 4ZZBA 5JMEA 5HCMA 2WN9A 5HEUA 5KZUA 2XZ5A 5LXBA 3JAEA 2XQ4A 5CO5A 3RIAA 2BYNA 4NZBA 2XQ7A 5J5FA 5LG3A 4A97A 2XQ5A 5CFBA 4HFBA 4HFHA 4TNWA 5AFKA 4HFEA 3IGQA 4ILCA 3SQ6A 2VL0A 4ILAA 3ZDHA 4LMJA 5HEHA 4QH4A 3U8NA 3U8KA 2W8FA 3PMZA 5HCJA 2BG9E 2XQ3A 3UU6A 5L4EA 3TLWA 5AFHA 2YMEA 2BYRA 2XNUA 4AFTA 3JADA 3TLSA 3ZKRA 2XQ9A 3EI0A 4XK9A 4UM3A 2Y54A 4ZR6A 3RHWA 3EAMA 3SH1A 3WTJA 4ZJTA 4B5DA 5IUXA 2Y56A 2ZJUA 3UU5A 2XNVA 2WNCA 4IL9A 4F8HA 4DBMA 1I9BA 4XHEA 3P50A 4ALXA 5BRXA 3JAFA 4AFHA 5L47A 4WV9A 3WTKA
chains in the Genus database with same CATH superfamily
4X5TA 3UQ4A 5KE4A 2QC1B 4HQPA 2XZ6A 4TWFA 2X00D 3WTIA 5J5HA 2BYSA 2XQAA 3U8MA 3U8LA 4ILBA 2WNJA 2PGZA 5AFMB 4COFA 2XYSA 2WZYA 3UU3A 3ZDGA 4BQTA 2BG9B 4AFGA 2YOEA 4QH5A 3WTLA 2Y7YA 5AFLA 3P4WA 3LSVA 2BR7A 4TWDA 4EZ1A 4ZRUA 3U8JA 2C9TA 3WIPA 2XQ6A 4TWHA 3T4MA 3RQUA 4LMLA 4PIRA 2YMDA 5TVCA 4D01A 5FJVA 4FRRA 4UY2A 4A98A 4UXUA 2UZ6A 4BFQA 3EHZA 4ZK1A 3GUAA 5BP0A 2YN6A 4LMKA 2Y57A 3TLVA 2W8GA 5AINA 4ZJSA 2YKSA 4NPPA 5HEGA 5HEJA 4QABA 3RI5A 3TLUA 3UU4A 3C84A 5AFJA 3SIOA 4HFDA 2ZJVA 3SQ9A 2X00A 3UUBA 2XQ8A 3TLTA 4QACA 3UQ7A 4HFIA 4QH1A 5AFMA 5AFNA 1UW6A 3WTMA 4TNVA 4UM3P 3UU8A 2BYQA 5J5GA 2XNTA 4UM1A 2Y58A 2BG9A 4QAAA 1UV6A 5HEOA 3WTNA 2WNLA 3PEOA 5BW2A 2BR8A 2PH9A 5SYOA 4Z91A 2XYTA 4ZZCA 2BJ0A 4IREA 5L4HA 4IL4A 5J5IA 2BG9C 4HFCA 4Z90A 3C79A 3RQWA 3WTHA 4UM3S 1UX2A 3RIFA 2BYPA 5J0ZA 3WTOA 4ZK4A 4ZZBA 5JMEA 5HCMA 2WN9A 5HEUA 5KZUA 2XZ5A 5LXBA 3JAEA 2XQ4A 5CO5A 3RIAA 2BYNA 4NZBA 2XQ7A 5J5FA 5LG3A 4A97A 2XQ5A 5CFBA 4HFBA 4HFHA 4TNWA 5AFKA 4HFEA 3IGQA 4ILCA 3SQ6A 2VL0A 4ILAA 3ZDHA 4LMJA 5HEHA 4QH4A 3U8NA 3U8KA 2W8FA 3PMZA 5HCJA 2BG9E 2XQ3A 3UU6A 5L4EA 3TLWA 5AFHA 2YMEA 2BYRA 2XNUA 4AFTA 3JADA 3TLSA 3ZKRA 2XQ9A 3EI0A 4XK9A 4UM3A 2Y54A 4ZR6A 3RHWA 3EAMA 3SH1A 3WTJA 4ZJTA 4B5DA 5IUXA 2Y56A 2ZJUA 3UU5A 2XNVA 2WNCA 4IL9A 4F8HA 4DBMA 1I9BA 4XHEA 3P50A 4ALXA 5BRXA 3JAFA 4AFHA 5L47A 4WV9A 3WTKA
chains in the Genus database with same CATH topology
4X5TA 3UQ4A 5KE4A 2QC1B 4HQPA 2XZ6A 4TWFA 2X00D 3WTIA 5J5HA 2BYSA 2XQAA 3U8MA 3U8LA 4ILBA 2WNJA 2PGZA 5AFMB 4COFA 2XYSA 2WZYA 3UU3A 3ZDGA 4BQTA 2BG9B 4AFGA 2YOEA 4QH5A 3WTLA 2Y7YA 5AFLA 3P4WA 3LSVA 2BR7A 4TWDA 4EZ1A 4ZRUA 3U8JA 2C9TA 3WIPA 2XQ6A 4TWHA 3T4MA 3RQUA 4LMLA 4PIRA 2YMDA 5TVCA 4D01A 5FJVA 4FRRA 4UY2A 4A98A 4UXUA 2UZ6A 4BFQA 3EHZA 4ZK1A 3GUAA 5BP0A 2YN6A 4LMKA 2Y57A 3TLVA 2W8GA 5AINA 4ZJSA 2YKSA 4NPPA 5HEGA 5HEJA 4QABA 3RI5A 3TLUA 3UU4A 3C84A 5AFJA 3SIOA 4HFDA 2ZJVA 3SQ9A 2X00A 3UUBA 2XQ8A 3TLTA 4QACA 3UQ7A 4HFIA 4QH1A 5AFMA 5AFNA 1UW6A 3WTMA 4TNVA 4UM3P 3UU8A 2BYQA 5J5GA 2XNTA 4UM1A 2Y58A 2BG9A 4QAAA 1UV6A 5HEOA 3WTNA 2WNLA 3PEOA 5BW2A 2BR8A 2PH9A 5SYOA 4Z91A 2XYTA 4ZZCA 2BJ0A 4IREA 5L4HA 4IL4A 5J5IA 2BG9C 4HFCA 4Z90A 3C79A 3RQWA 3WTHA 4UM3S 1UX2A 3RIFA 2BYPA 5J0ZA 3WTOA 4ZK4A 4ZZBA 5JMEA 5HCMA 2WN9A 5HEUA 5KZUA 2XZ5A 5LXBA 3JAEA 2XQ4A 5CO5A 3RIAA 2BYNA 4NZBA 2XQ7A 5J5FA 5LG3A 4A97A 2XQ5A 5CFBA 4HFBA 4HFHA 4TNWA 5AFKA 4HFEA 3IGQA 4ILCA 3SQ6A 2VL0A 4ILAA 3ZDHA 4LMJA 5HEHA 4QH4A 3U8NA 3U8KA 2W8FA 3PMZA 5HCJA 2BG9E 2XQ3A 3UU6A 5L4EA 3TLWA 5AFHA 2YMEA 2BYRA 2XNUA 4AFTA 3JADA 3TLSA 3ZKRA 2XQ9A 3EI0A 4XK9A 4UM3A 2Y54A 4ZR6A 3RHWA 3EAMA 3SH1A 3WTJA 4ZJTA 4B5DA 5IUXA 2Y56A 2ZJUA 3UU5A 2XNVA 2WNCA 4IL9A 4F8HA 4DBMA 1I9BA 4XHEA 3P50A 4ALXA 5BRXA 3JAFA 4AFHA 5L47A 4WV9A 3WTKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4X5T A;  3UQ4 A;  5KE4 A;  2QC1 B;  4HQP A;  2XZ6 A;  4TWF A;  2X00 D;  3WTI A;  5J5H A;  2BYS A;  2XQA A;  3U8M A;  3U8L A;  4ILB A;  2WNJ A;  2PGZ A;  5AFM B;  4COF A;  2XYS A;  2WZY A;  3UU3 A;  3ZDG A;  4BQT A;  2BG9 B;  4AFG A;  2YOE A;  4QH5 A;  3WTL A;  2Y7Y A;  5AFL A;  3P4W A;  3LSV A;  2BR7 A;  4TWD A;  4EZ1 A;  4ZRU A;  3U8J A;  2C9T A;  3WIP A;  2XQ6 A;  4TWH A;  3T4M A;  3RQU A;  4LML A;  4PIR A;  2YMD A;  5TVC A;  4D01 A;  5FJV A;  4FRR A;  4UY2 A;  4A98 A;  4UXU A;  2UZ6 A;  4BFQ A;  3EHZ A;  4ZK1 A;  3GUA A;  5BP0 A;  2YN6 A;  4LMK A;  2Y57 A;  3TLV A;  2W8G A;  5AIN A;  4ZJS A;  2YKS A;  4NPP A;  5HEG A;  5HEJ A;  4QAB A;  3RI5 A;  3TLU A;  3UU4 A;  3C84 A;  5AFJ A;  3SIO A;  4HFD A;  2ZJV A;  3SQ9 A;  2X00 A;  3UUB A;  2XQ8 A;  3TLT A;  4QAC A;  3UQ7 A;  4HFI A;  4QH1 A;  5AFM A;  5AFN A;  1UW6 A;  3WTM A;  4TNV A;  4UM3 P;  3UU8 A;  2BYQ A;  5J5G A;  2XNT A;  4UM1 A;  2Y58 A;  2BG9 A;  4QAA A;  1UV6 A;  5HEO A;  3WTN A;  2WNL A;  3PEO A;  5BW2 A;  2BR8 A;  2PH9 A;  5SYO A;  4Z91 A;  2XYT A;  4ZZC A;  2BJ0 A;  4IRE A;  5L4H A;  4IL4 A;  5J5I A;  2BG9 C;  4HFC A;  4Z90 A;  3C79 A;  3RQW A;  3WTH A;  4UM3 S;  1UX2 A;  3RIF A;  2BYP A;  5J0Z A;  3WTO A;  4ZK4 A;  4ZZB A;  5JME A;  5HCM A;  2WN9 A;  5HEU A;  5KZU A;  2XZ5 A;  5LXB A;  3JAE A;  2XQ4 A;  5CO5 A;  3RIA A;  2BYN A;  4NZB A;  2XQ7 A;  5J5F A;  5LG3 A;  4A97 A;  2XQ5 A;  5CFB A;  4HFB A;  4HFH A;  4TNW A;  5AFK A;  4HFE A;  3IGQ A;  4ILC A;  3SQ6 A;  2VL0 A;  4ILA A;  3ZDH A;  4LMJ A;  5HEH A;  4QH4 A;  3U8N A;  3U8K A;  2W8F A;  3PMZ A;  5HCJ A;  2BG9 E;  2XQ3 A;  3UU6 A;  5L4E A;  3TLW A;  5AFH A;  2YME A;  2BYR A;  2XNU A;  4AFT A;  3JAD A;  3TLS A;  3ZKR A;  2XQ9 A;  3EI0 A;  4XK9 A;  4UM3 A;  2Y54 A;  4ZR6 A;  3RHW A;  3EAM A;  3SH1 A;  3WTJ A;  4ZJT A;  4B5D A;  5IUX A;  2Y56 A;  2ZJU A;  3UU5 A;  2XNV A;  2WNC A;  4IL9 A;  4F8H A;  4DBM A;  1I9B A;  4XHE A;  3P50 A;  4ALX A;  5BRX A;  3JAF A;  4AFH A;  5L47 A;  4WV9 A;  3WTK A; 
#chains in the Genus database with same CATH topology
 4X5T A;  3UQ4 A;  5KE4 A;  2QC1 B;  4HQP A;  2XZ6 A;  4TWF A;  2X00 D;  3WTI A;  5J5H A;  2BYS A;  2XQA A;  3U8M A;  3U8L A;  4ILB A;  2WNJ A;  2PGZ A;  5AFM B;  4COF A;  2XYS A;  2WZY A;  3UU3 A;  3ZDG A;  4BQT A;  2BG9 B;  4AFG A;  2YOE A;  4QH5 A;  3WTL A;  2Y7Y A;  5AFL A;  3P4W A;  3LSV A;  2BR7 A;  4TWD A;  4EZ1 A;  4ZRU A;  3U8J A;  2C9T A;  3WIP A;  2XQ6 A;  4TWH A;  3T4M A;  3RQU A;  4LML A;  4PIR A;  2YMD A;  5TVC A;  4D01 A;  5FJV A;  4FRR A;  4UY2 A;  4A98 A;  4UXU A;  2UZ6 A;  4BFQ A;  3EHZ A;  4ZK1 A;  3GUA A;  5BP0 A;  2YN6 A;  4LMK A;  2Y57 A;  3TLV A;  2W8G A;  5AIN A;  4ZJS A;  2YKS A;  4NPP A;  5HEG A;  5HEJ A;  4QAB A;  3RI5 A;  3TLU A;  3UU4 A;  3C84 A;  5AFJ A;  3SIO A;  4HFD A;  2ZJV A;  3SQ9 A;  2X00 A;  3UUB A;  2XQ8 A;  3TLT A;  4QAC A;  3UQ7 A;  4HFI A;  4QH1 A;  5AFM A;  5AFN A;  1UW6 A;  3WTM A;  4TNV A;  4UM3 P;  3UU8 A;  2BYQ A;  5J5G A;  2XNT A;  4UM1 A;  2Y58 A;  2BG9 A;  4QAA A;  1UV6 A;  5HEO A;  3WTN A;  2WNL A;  3PEO A;  5BW2 A;  2BR8 A;  2PH9 A;  5SYO A;  4Z91 A;  2XYT A;  4ZZC A;  2BJ0 A;  4IRE A;  5L4H A;  4IL4 A;  5J5I A;  2BG9 C;  4HFC A;  4Z90 A;  3C79 A;  3RQW A;  3WTH A;  4UM3 S;  1UX2 A;  3RIF A;  2BYP A;  5J0Z A;  3WTO A;  4ZK4 A;  4ZZB A;  5JME A;  5HCM A;  2WN9 A;  5HEU A;  5KZU A;  2XZ5 A;  5LXB A;  3JAE A;  2XQ4 A;  5CO5 A;  3RIA A;  2BYN A;  4NZB A;  2XQ7 A;  5J5F A;  5LG3 A;  4A97 A;  2XQ5 A;  5CFB A;  4HFB A;  4HFH A;  4TNW A;  5AFK A;  4HFE A;  3IGQ A;  4ILC A;  3SQ6 A;  2VL0 A;  4ILA A;  3ZDH A;  4LMJ A;  5HEH A;  4QH4 A;  3U8N A;  3U8K A;  2W8F A;  3PMZ A;  5HCJ A;  2BG9 E;  2XQ3 A;  3UU6 A;  5L4E A;  3TLW A;  5AFH A;  2YME A;  2BYR A;  2XNU A;  4AFT A;  3JAD A;  3TLS A;  3ZKR A;  2XQ9 A;  3EI0 A;  4XK9 A;  4UM3 A;  2Y54 A;  4ZR6 A;  3RHW A;  3EAM A;  3SH1 A;  3WTJ A;  4ZJT A;  4B5D A;  5IUX A;  2Y56 A;  2ZJU A;  3UU5 A;  2XNV A;  2WNC A;  4IL9 A;  4F8H A;  4DBM A;  1I9B A;  4XHE A;  3P50 A;  4ALX A;  5BRX A;  3JAF A;  4AFH A;  5L47 A;  4WV9 A;  3WTK A; 
#chains in the Genus database with same CATH homology
 4X5T A;  3UQ4 A;  5KE4 A;  2QC1 B;  4HQP A;  2XZ6 A;  4TWF A;  2X00 D;  3WTI A;  5J5H A;  2BYS A;  2XQA A;  3U8M A;  3U8L A;  4ILB A;  2WNJ A;  2PGZ A;  5AFM B;  4COF A;  2XYS A;  2WZY A;  3UU3 A;  3ZDG A;  4BQT A;  2BG9 B;  4AFG A;  2YOE A;  4QH5 A;  3WTL A;  2Y7Y A;  5AFL A;  3P4W A;  3LSV A;  2BR7 A;  4TWD A;  4EZ1 A;  4ZRU A;  3U8J A;  2C9T A;  3WIP A;  2XQ6 A;  4TWH A;  3T4M A;  3RQU A;  4LML A;  4PIR A;  2YMD A;  5TVC A;  4D01 A;  5FJV A;  4FRR A;  4UY2 A;  4A98 A;  4UXU A;  2UZ6 A;  4BFQ A;  3EHZ A;  4ZK1 A;  3GUA A;  5BP0 A;  2YN6 A;  4LMK A;  2Y57 A;  3TLV A;  2W8G A;  5AIN A;  4ZJS A;  2YKS A;  4NPP A;  5HEG A;  5HEJ A;  4QAB A;  3RI5 A;  3TLU A;  3UU4 A;  3C84 A;  5AFJ A;  3SIO A;  4HFD A;  2ZJV A;  3SQ9 A;  2X00 A;  3UUB A;  2XQ8 A;  3TLT A;  4QAC A;  3UQ7 A;  4HFI A;  4QH1 A;  5AFM A;  5AFN A;  1UW6 A;  3WTM A;  4TNV A;  4UM3 P;  3UU8 A;  2BYQ A;  5J5G A;  2XNT A;  4UM1 A;  2Y58 A;  2BG9 A;  4QAA A;  1UV6 A;  5HEO A;  3WTN A;  2WNL A;  3PEO A;  5BW2 A;  2BR8 A;  2PH9 A;  5SYO A;  4Z91 A;  2XYT A;  4ZZC A;  2BJ0 A;  4IRE A;  5L4H A;  4IL4 A;  5J5I A;  2BG9 C;  4HFC A;  4Z90 A;  3C79 A;  3RQW A;  3WTH A;  4UM3 S;  1UX2 A;  3RIF A;  2BYP A;  5J0Z A;  3WTO A;  4ZK4 A;  4ZZB A;  5JME A;  5HCM A;  2WN9 A;  5HEU A;  5KZU A;  2XZ5 A;  5LXB A;  3JAE A;  2XQ4 A;  5CO5 A;  3RIA A;  2BYN A;  4NZB A;  2XQ7 A;  5J5F A;  5LG3 A;  4A97 A;  2XQ5 A;  5CFB A;  4HFB A;  4HFH A;  4TNW A;  5AFK A;  4HFE A;  3IGQ A;  4ILC A;  3SQ6 A;  2VL0 A;  4ILA A;  3ZDH A;  4LMJ A;  5HEH A;  4QH4 A;  3U8N A;  3U8K A;  2W8F A;  3PMZ A;  5HCJ A;  2BG9 E;  2XQ3 A;  3UU6 A;  5L4E A;  3TLW A;  5AFH A;  2YME A;  2BYR A;  2XNU A;  4AFT A;  3JAD A;  3TLS A;  3ZKR A;  2XQ9 A;  3EI0 A;  4XK9 A;  4UM3 A;  2Y54 A;  4ZR6 A;  3RHW A;  3EAM A;  3SH1 A;  3WTJ A;  4ZJT A;  4B5D A;  5IUX A;  2Y56 A;  2ZJU A;  3UU5 A;  2XNV A;  2WNC A;  4IL9 A;  4F8H A;  4DBM A;  1I9B A;  4XHE A;  3P50 A;  4ALX A;  5BRX A;  3JAF A;  4AFH A;  5L47 A;  4WV9 A;  3WTK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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