2X83A

Evolutionary basis of hiv restriction by the antiretroviral trimcyp
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
146
structure length
146
Chain Sequence
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Conformational adaptation of Asian macaque TRIMCyp directs lineage specific antiviral activity.
pubmed doi rcsb
molecule keywords HIV-1 CAPSID
source organism Human immunodeficiency virus 1
molecule tags Viral protein
total genus 49
structure length 146
sequence length 146
chains with identical sequence C
ec nomenclature
pdb deposition date 2010-03-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 2x83A00
1M9EC 1U7KA 3BP9A 2PXRC 4HTWA 5JPAA 1D1DA 1GWPA 1M9XC 1AFVA 1M9FC 1P7NA 2M8PA 2JPRA 4DGEC 2M8LA 1M9YC 4XROA 4DGAC 3P05A 2KGFA 1EM9A 2WLVA 4LQWC 5HGNA 2XGYA 2GOLB 4U0AA 1QRJA 2X82A 2LF4A 2EIAA 4E92A 4NX4C 2PWOA 4E91A 3MGEA 4QNBA 1M9CC 4U0CA 5HGMA 5HGKA 2V4XA 4WYMA 2M8NA 2X83A 5HGOA 4U0EA 2Y4ZA 2X2DD 1G03A 4PH0A 1E6JP 3H47A 4J93A 4B4NA 4XRQA 4U0FA 4XFXA 2GONA 4PH2A 2WLVB 4INBA 1L6NA 1EIAA 4U0BA 4XFZA 1AK4C 2XGUA 4XFYA 5HGLA 1M9DC 2PWMA 4PH3A 2XGVA 4U0DA 2XDEA 3NTEA 3H4EA
chains in the Genus database with same CATH superfamily
1M9EC 1U7KA 3BP9A 2PXRC 4HTWA 5JPAA 1D1DA 1GWPA 1M9XC 1AFVA 1M9FC 1P7NA 2M8PA 2JPRA 4DGEC 2M8LA 1M9YC 4XROA 4DGAC 3P05A 2KGFA 1EM9A 2WLVA 4LQWC 5HGNA 2XGYA 2GOLB 4U0AA 1QRJA 2X82A 2LF4A 2EIAA 4E92A 4NX4C 2PWOA 4E91A 3MGEA 4QNBA 1M9CC 4U0CA 5HGMA 5HGKA 2V4XA 4WYMA 2M8NA 2X83A 5HGOA 4U0EA 2Y4ZA 2X2DD 1G03A 4PH0A 1E6JP 3H47A 4J93A 4B4NA 4XRQA 4U0FA 4XFXA 2GONA 4PH2A 2WLVB 4INBA 1L6NA 1EIAA 4U0BA 4XFZA 1AK4C 2XGUA 4XFYA 5HGLA 1M9DC 2PWMA 4PH3A 2XGVA 4U0DA 2XDEA 3NTEA 3H4EA
chains in the Genus database with same CATH topology
1M9EC 1U7KA 3BP9A 2PXRC 4HTWA 5JPAA 1D1DA 1GWPA 1M9XC 1AFVA 1M9FC 1P7NA 2M8PA 2JPRA 4DGEC 2M8LA 1M9YC 4XROA 4DGAC 3P05A 2KGFA 1EM9A 2WLVA 4LQWC 5HGNA 2XGYA 2GOLB 4U0AA 1QRJA 2X82A 2LF4A 2EIAA 4E92A 4NX4C 2PWOA 4E91A 3MGEA 4QNBA 1M9CC 4U0CA 5HGMA 5HGKA 2V4XA 4WYMA 2M8NA 2X83A 5HGOA 4U0EA 2Y4ZA 2X2DD 1G03A 4PH0A 1E6JP 3H47A 4J93A 4B4NA 4XRQA 4U0FA 4XFXA 2GONA 4PH2A 2WLVB 4INBA 1L6NA 1EIAA 4U0BA 4XFZA 1AK4C 2XGUA 4XFYA 5HGLA 1M9DC 2PWMA 4PH3A 2XGVA 4U0DA 2XDEA 3NTEA 3H4EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M9E C;  1U7K A;  3BP9 A;  2PXR C;  4HTW A;  5JPA A;  1D1D A;  1GWP A;  1M9X C;  1AFV A;  1M9F C;  1P7N A;  2M8P A;  2JPR A;  4DGE C;  2M8L A;  1M9Y C;  4XRO A;  4DGA C;  3P05 A;  2KGF A;  1EM9 A;  2WLV A;  4LQW C;  5HGN A;  2XGY A;  2GOL B;  4U0A A;  1QRJ A;  2X82 A;  2LF4 A;  2EIA A;  4E92 A;  4NX4 C;  2PWO A;  4E91 A;  3MGE A;  4QNB A;  1M9C C;  4U0C A;  5HGM A;  5HGK A;  2V4X A;  4WYM A;  2M8N A;  2X83 A;  5HGO A;  4U0E A;  2Y4Z A;  2X2D D;  1G03 A;  4PH0 A;  1E6J P;  3H47 A;  4J93 A;  4B4N A;  4XRQ A;  4U0F A;  4XFX A;  2GON A;  4PH2 A;  2WLV B;  4INB A;  1L6N A;  1EIA A;  4U0B A;  4XFZ A;  1AK4 C;  2XGU A;  4XFY A;  5HGL A;  1M9D C;  2PWM A;  4PH3 A;  2XGV A;  4U0D A;  2XDE A;  3NTE A;  3H4E A; 
#chains in the Genus database with same CATH topology
 1M9E C;  1U7K A;  3BP9 A;  2PXR C;  4HTW A;  5JPA A;  1D1D A;  1GWP A;  1M9X C;  1AFV A;  1M9F C;  1P7N A;  2M8P A;  2JPR A;  4DGE C;  2M8L A;  1M9Y C;  4XRO A;  4DGA C;  3P05 A;  2KGF A;  1EM9 A;  2WLV A;  4LQW C;  5HGN A;  2XGY A;  2GOL B;  4U0A A;  1QRJ A;  2X82 A;  2LF4 A;  2EIA A;  4E92 A;  4NX4 C;  2PWO A;  4E91 A;  3MGE A;  4QNB A;  1M9C C;  4U0C A;  5HGM A;  5HGK A;  2V4X A;  4WYM A;  2M8N A;  2X83 A;  5HGO A;  4U0E A;  2Y4Z A;  2X2D D;  1G03 A;  4PH0 A;  1E6J P;  3H47 A;  4J93 A;  4B4N A;  4XRQ A;  4U0F A;  4XFX A;  2GON A;  4PH2 A;  2WLV B;  4INB A;  1L6N A;  1EIA A;  4U0B A;  4XFZ A;  1AK4 C;  2XGU A;  4XFY A;  5HGL A;  1M9D C;  2PWM A;  4PH3 A;  2XGV A;  4U0D A;  2XDE A;  3NTE A;  3H4E A; 
#chains in the Genus database with same CATH homology
 1M9E C;  1U7K A;  3BP9 A;  2PXR C;  4HTW A;  5JPA A;  1D1D A;  1GWP A;  1M9X C;  1AFV A;  1M9F C;  1P7N A;  2M8P A;  2JPR A;  4DGE C;  2M8L A;  1M9Y C;  4XRO A;  4DGA C;  3P05 A;  2KGF A;  1EM9 A;  2WLV A;  4LQW C;  5HGN A;  2XGY A;  2GOL B;  4U0A A;  1QRJ A;  2X82 A;  2LF4 A;  2EIA A;  4E92 A;  4NX4 C;  2PWO A;  4E91 A;  3MGE A;  4QNB A;  1M9C C;  4U0C A;  5HGM A;  5HGK A;  2V4X A;  4WYM A;  2M8N A;  2X83 A;  5HGO A;  4U0E A;  2Y4Z A;  2X2D D;  1G03 A;  4PH0 A;  1E6J P;  3H47 A;  4J93 A;  4B4N A;  4XRQ A;  4U0F A;  4XFX A;  2GON A;  4PH2 A;  2WLV B;  4INB A;  1L6N A;  1EIA A;  4U0B A;  4XFZ A;  1AK4 C;  2XGU A;  4XFY A;  5HGL A;  1M9D C;  2PWM A;  4PH3 A;  2XGV A;  4U0D A;  2XDE A;  3NTE A;  3H4E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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