2XD7A

Crystal structure of the macro domain of human core histone h2a
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
192
structure length
192
Chain Sequence
GPGDGFTILSSKSLVLGQKLSLTQSDISHIGSMRVEGIVHPTTAEIDLKEDIGKALEKAGGKEFLETVKELRKSQGPLEVAEAAVSQSSGLAAKFVIHCHIPQWGSDKCEEQLEETIKNCLSAAEDKKLKSVAFPPFPSGRNCFPKQTAAQVTLKAISAHFDDSSASSLKNVYFLLFDSESIGIYVQEMAKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Macro Domain of Human Core Histone H2A
rcsb
molecule tags Dna binding protein
source organism Homo sapiens
molecule keywords CORE HISTONE MACRO-H2A.2
total genus 63
structure length 192
sequence length 192
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2010-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 2xd7A00
3VFQA 3EWPA 3GPGA 5CB3A 3KQXA 4J5RA 3IIFA 3KR5A 5FSXA 4R7MA 3IIDA 1LAMA 2EWBA 1ZR3A 4JGKA 4ZI6A 3V45A 2DX6A 2J9AA 3SIHA 3SIGA 5E3BA 2EEEA 4TU0A 4J5QA 3GQOA 3EWRA 4JCAA 5HOLA 4ETKA 3H8FA 3GPQA 2LGRA 5FSZA 3KZWA 2BFQA 2ACFA 3ETIA 5CB5A 4K3NA 2FXKA 3H8EA 4GUAA 3KQZA 3V2BA 2XD7A 4ZY0A 3SIJA 4J5SA 1LANA 3EKEA 3T8WA 1HJZA 4D86A 2VRIA 3PEIA 3EJGA 4ETJA 1LCPA 1YD9A 1ZR5A 2X47A 5AILA 4ZX8A 4ABLA 3EW5A 3JZTA 4X2TA 3JRUA 3GQEA 3KR4A 4ABKA 4R76A 4IQYA 4KYBA 4JLLA 5CBMA 4JVVA 4J4ZA 4KSIA 2L8RA 5DUSA 1BLLE 4ESSA 1VHUA 4ZY1A 3EWQA 4K0CA 2FG1A 3EJFA 5FSUA 3IJ3A 1BPNA 1BPMA 2FAVA 3H8GA 1GYTA 5CMSA 4ZY2A 3SIIA 5FSVA 4ZX9A 3GPOA 1SPVA 2AFCA 1TXZA 4ZYQA 1TY8A 4UMLA 3Q71A 1LAPA 5D8NA 3Q6ZA 5HIHA 5FSYA 4GVWA 4R6TA 4GVVA 3EWOA 1NJRA 2BFRA
chains in the Genus database with same CATH superfamily
3VFQA 3EWPA 3GPGA 5CB3A 3KQXA 4J5RA 2WCTA 3IIFA 3KR5A 5FSXA 4R7MA 3IIDA 1LAMA 2EWBA 1ZR3A 4JGKA 4ZI6A 3V45A 2DX6A 2J9AA 3SIHA 3SIGA 5E3BA 2EEEA 4TU0A 4J5QA 3GQOA 3EWRA 4JCAA 2JZDA 5HOLA 4ETKA 3H8FA 3GPQA 2LGRA 5FSZA 3KZWA 2BFQA 2ACFA 3ETIA 5CB5A 4K3NA 2FXKA 3H8EA 4GUAA 3KQZA 3V2BA 2XD7A 4ZY0A 3SIJA 4J5SA 1LANA 3EKEA 3T8WA 1HJZA 4D86A 2VRIA 3PEIA 3EJGA 4ETJA 1LCPA 1YD9A 2KQVA 1ZR5A 2X47A 5AILA 4ZX8A 4ABLA 3EW5A 3JZTA 4X2TA 3JRUA 3GQEA 3KR4A 4ABKA 4R76A 4IQYA 4KYBA 4JLLA 5CBMA 4JVVA 4J4ZA 4KSIA 2L8RA 5DUSA 1BLLE 4ESSA 1VHUA 4ZY1A 3EWQA 4K0CA 2FG1A 2W2GA 3EJFA 5FSUA 3IJ3A 1BPNA 1BPMA 2FAVA 3H8GA 1GYTA 2JZFA 5CMSA 4ZY2A 3SIIA 5FSVA 4ZX9A 3GPOA 1SPVA 2AFCA 1TXZA 4ZYQA 1TY8A 4UMLA 3Q71A 2RNKA 1LAPA 5D8NA 3Q6ZA 5HIHA 5FSYA 4GVWA 4R6TA 4GVVA 3EWOA 1NJRA 2JZEA 2BFRA
chains in the Genus database with same CATH topology
3VFQA 3EWPA 3GPGA 5CB3A 3KQXA 4J5RA 3IIFA 3KR5A 5FSXA 4R7MA 3IIDA 1LAMA 2EWBA 1ZR3A 4JGKA 4ZI6A 3V45A 2DX6A 2J9AA 3SIHA 3SIGA 5E3BA 2EEEA 4TU0A 4J5QA 3GQOA 3EWRA 4JCAA 5HOLA 4ETKA 3H8FA 3GPQA 2LGRA 5FSZA 3KZWA 2BFQA 2ACFA 3ETIA 5CB5A 4K3NA 2FXKA 3H8EA 4GUAA 3KQZA 3V2BA 2XD7A 4ZY0A 3SIJA 4J5SA 1LANA 3EKEA 3T8WA 1HJZA 4D86A 2VRIA 3PEIA 3EJGA 4ETJA 1LCPA 1YD9A 1ZR5A 2X47A 5AILA 4ZX8A 4ABLA 3EW5A 3JZTA 4X2TA 3JRUA 3GQEA 3KR4A 4ABKA 4R76A 4IQYA 4KYBA 4JLLA 5CBMA 4JVVA 4J4ZA 4KSIA 2L8RA 5DUSA 1BLLE 4ESSA 1VHUA 4ZY1A 3EWQA 4K0CA 2FG1A 3EJFA 5FSUA 3IJ3A 1BPNA 1BPMA 2FAVA 3H8GA 1GYTA 5CMSA 4ZY2A 3SIIA 5FSVA 4ZX9A 3GPOA 1SPVA 2AFCA 1TXZA 4ZYQA 1TY8A 4UMLA 3Q71A 1LAPA 5D8NA 3Q6ZA 5HIHA 5FSYA 4GVWA 4R6TA 4GVVA 3EWOA 1NJRA 2BFRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VFQ A;  3EWP A;  3GPG A;  5CB3 A;  3KQX A;  4J5R A;  3IIF A;  3KR5 A;  5FSX A;  4R7M A;  3IID A;  1LAM A;  2EWB A;  1ZR3 A;  4JGK A;  4ZI6 A;  3V45 A;  2DX6 A;  2J9A A;  3SIH A;  3SIG A;  5E3B A;  2EEE A;  4TU0 A;  4J5Q A;  3GQO A;  3EWR A;  4JCA A;  5HOL A;  4ETK A;  3H8F A;  3GPQ A;  2LGR A;  5FSZ A;  3KZW A;  2BFQ A;  2ACF A;  3ETI A;  5CB5 A;  4K3N A;  2FXK A;  3H8E A;  4GUA A;  3KQZ A;  3V2B A;  2XD7 A;  4ZY0 A;  3SIJ A;  4J5S A;  1LAN A;  3EKE A;  3T8W A;  1HJZ A;  4D86 A;  2VRI A;  3PEI A;  3EJG A;  4ETJ A;  1LCP A;  1YD9 A;  1ZR5 A;  2X47 A;  5AIL A;  4ZX8 A;  4ABL A;  3EW5 A;  3JZT A;  4X2T A;  3JRU A;  3GQE A;  3KR4 A;  4ABK A;  4R76 A;  4IQY A;  4KYB A;  4JLL A;  5CBM A;  4JVV A;  4J4Z A;  4KSI A;  2L8R A;  5DUS A;  1BLL E;  4ESS A;  1VHU A;  4ZY1 A;  3EWQ A;  4K0C A;  2FG1 A;  3EJF A;  5FSU A;  3IJ3 A;  1BPN A;  1BPM A;  2FAV A;  3H8G A;  1GYT A;  5CMS A;  4ZY2 A;  3SII A;  5FSV A;  4ZX9 A;  3GPO A;  1SPV A;  2AFC A;  1TXZ A;  4ZYQ A;  1TY8 A;  4UML A;  3Q71 A;  1LAP A;  5D8N A;  3Q6Z A;  5HIH A;  5FSY A;  4GVW A;  4R6T A;  4GVV A;  3EWO A;  1NJR A;  2BFR A; 
#chains in the Genus database with same CATH topology
 3VFQ A;  3EWP A;  3GPG A;  5CB3 A;  3KQX A;  4J5R A;  2WCT A;  3IIF A;  3KR5 A;  5FSX A;  4R7M A;  3IID A;  1LAM A;  2EWB A;  1ZR3 A;  4JGK A;  4ZI6 A;  3V45 A;  2DX6 A;  2J9A A;  3SIH A;  3SIG A;  5E3B A;  2EEE A;  4TU0 A;  4J5Q A;  3GQO A;  3EWR A;  4JCA A;  2JZD A;  5HOL A;  4ETK A;  3H8F A;  3GPQ A;  2LGR A;  5FSZ A;  3KZW A;  2BFQ A;  2ACF A;  3ETI A;  5CB5 A;  4K3N A;  2FXK A;  3H8E A;  4GUA A;  3KQZ A;  3V2B A;  2XD7 A;  4ZY0 A;  3SIJ A;  4J5S A;  1LAN A;  3EKE A;  3T8W A;  1HJZ A;  4D86 A;  2VRI A;  3PEI A;  3EJG A;  4ETJ A;  1LCP A;  1YD9 A;  2KQV A;  1ZR5 A;  2X47 A;  5AIL A;  4ZX8 A;  4ABL A;  3EW5 A;  3JZT A;  4X2T A;  3JRU A;  3GQE A;  3KR4 A;  4ABK A;  4R76 A;  4IQY A;  4KYB A;  4JLL A;  5CBM A;  4JVV A;  4J4Z A;  4KSI A;  2L8R A;  5DUS A;  1BLL E;  4ESS A;  1VHU A;  4ZY1 A;  3EWQ A;  4K0C A;  2FG1 A;  2W2G A;  3EJF A;  5FSU A;  3IJ3 A;  1BPN A;  1BPM A;  2FAV A;  3H8G A;  1GYT A;  2JZF A;  5CMS A;  4ZY2 A;  3SII A;  5FSV A;  4ZX9 A;  3GPO A;  1SPV A;  2AFC A;  1TXZ A;  4ZYQ A;  1TY8 A;  4UML A;  3Q71 A;  2RNK A;  1LAP A;  5D8N A;  3Q6Z A;  5HIH A;  5FSY A;  4GVW A;  4R6T A;  4GVV A;  3EWO A;  1NJR A;  2JZE A;  2BFR A; 
#chains in the Genus database with same CATH homology
 3VFQ A;  3EWP A;  3GPG A;  5CB3 A;  3KQX A;  4J5R A;  3IIF A;  3KR5 A;  5FSX A;  4R7M A;  3IID A;  1LAM A;  2EWB A;  1ZR3 A;  4JGK A;  4ZI6 A;  3V45 A;  2DX6 A;  2J9A A;  3SIH A;  3SIG A;  5E3B A;  2EEE A;  4TU0 A;  4J5Q A;  3GQO A;  3EWR A;  4JCA A;  5HOL A;  4ETK A;  3H8F A;  3GPQ A;  2LGR A;  5FSZ A;  3KZW A;  2BFQ A;  2ACF A;  3ETI A;  5CB5 A;  4K3N A;  2FXK A;  3H8E A;  4GUA A;  3KQZ A;  3V2B A;  2XD7 A;  4ZY0 A;  3SIJ A;  4J5S A;  1LAN A;  3EKE A;  3T8W A;  1HJZ A;  4D86 A;  2VRI A;  3PEI A;  3EJG A;  4ETJ A;  1LCP A;  1YD9 A;  1ZR5 A;  2X47 A;  5AIL A;  4ZX8 A;  4ABL A;  3EW5 A;  3JZT A;  4X2T A;  3JRU A;  3GQE A;  3KR4 A;  4ABK A;  4R76 A;  4IQY A;  4KYB A;  4JLL A;  5CBM A;  4JVV A;  4J4Z A;  4KSI A;  2L8R A;  5DUS A;  1BLL E;  4ESS A;  1VHU A;  4ZY1 A;  3EWQ A;  4K0C A;  2FG1 A;  3EJF A;  5FSU A;  3IJ3 A;  1BPN A;  1BPM A;  2FAV A;  3H8G A;  1GYT A;  5CMS A;  4ZY2 A;  3SII A;  5FSV A;  4ZX9 A;  3GPO A;  1SPV A;  2AFC A;  1TXZ A;  4ZYQ A;  1TY8 A;  4UML A;  3Q71 A;  1LAP A;  5D8N A;  3Q6Z A;  5HIH A;  5FSY A;  4GVW A;  4R6T A;  4GVV A;  3EWO A;  1NJR A;  2BFR A; 
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similar chains in the Genus database (?% sequence similarity)
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