2XDGA

Crystal structure of the extracellular domain of human growth hormone releasing hormone receptor.
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
89
structure length
89
Chain Sequence
MLREDESACLQAAEEMPQTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords GROWTH HORMONE-RELEASING HORMONE RECEPTOR
publication title Crystal Structure of the Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor.
rcsb
source organism Homo sapiens
total genus 16
structure length 89
sequence length 89
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-04-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02793 HRM Hormone receptor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.1240.10 Few Secondary Structures Irregular Hormone receptor fold GPCR, family 2, extracellular hormone receptor domain 2xdgA01
3N7PA 3AQFB 3C59A 3C5TA 3H3GA 4DLOA 1U34A 3L2JA 4ZGMA 2JNDA 2XDGA 5II0A 2L27A 3EHSA 4LF3C 3IOLA 4HJ0A 3C4MA 3EHUA 2JODA 3EHTA 4DLQA 4ERSA 3N7SA 2QKHA 3N7RA 2JNCA
chains in the Genus database with same CATH superfamily
3N7PA 3AQFB 3C59A 3C5TA 3H3GA 4DLOA 1U34A 3L2JA 4ZGMA 2JNDA 2XDGA 5II0A 2L27A 3EHSA 4LF3C 3IOLA 4HJ0A 3C4MA 3EHUA 2JODA 3EHTA 4DLQA 4ERSA 3N7SA 2QKHA 3N7RA 2JNCA
chains in the Genus database with same CATH topology
3N7PA 3AQFB 3C59A 3C5TA 3H3GA 4DLOA 1U34A 3L2JA 4ZGMA 2JNDA 2XDGA 5II0A 2L27A 3EHSA 4LF3C 3IOLA 4HJ0A 3C4MA 3EHUA 2JODA 3EHTA 4DLQA 4ERSA 3N7SA 2QKHA 3N7RA 2JNCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3N7P A;  3AQF B;  3C59 A;  3C5T A;  3H3G A;  4DLO A;  1U34 A;  3L2J A;  4ZGM A;  2JND A;  2XDG A;  5II0 A;  2L27 A;  3EHS A;  4LF3 C;  3IOL A;  4HJ0 A;  3C4M A;  3EHU A;  2JOD A;  3EHT A;  4DLQ A;  4ERS A;  3N7S A;  2QKH A;  3N7R A;  2JNC A; 
#chains in the Genus database with same CATH topology
 3N7P A;  3AQF B;  3C59 A;  3C5T A;  3H3G A;  4DLO A;  1U34 A;  3L2J A;  4ZGM A;  2JND A;  2XDG A;  5II0 A;  2L27 A;  3EHS A;  4LF3 C;  3IOL A;  4HJ0 A;  3C4M A;  3EHU A;  2JOD A;  3EHT A;  4DLQ A;  4ERS A;  3N7S A;  2QKH A;  3N7R A;  2JNC A; 
#chains in the Genus database with same CATH homology
 3N7P A;  3AQF B;  3C59 A;  3C5T A;  3H3G A;  4DLO A;  1U34 A;  3L2J A;  4ZGM A;  2JND A;  2XDG A;  5II0 A;  2L27 A;  3EHS A;  4LF3 C;  3IOL A;  4HJ0 A;  3C4M A;  3EHU A;  2JOD A;  3EHT A;  4DLQ A;  4ERS A;  3N7S A;  2QKH A;  3N7R A;  2JNC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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