2XNFA

The mediator med25 activator interaction domain: structure and cooperative binding of vp16 subdomains
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
159
structure length
159
Chain Sequence
MSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNLEHHHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transcription
molecule keywords MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25
publication title Structure and Vp16 Binding of the Mediator Med25 Activator Interaction Domain.
pubmed doi rcsb
source organism Homo sapiens
total genus 36
structure length 159
sequence length 159
ec nomenclature
pdb deposition date 2010-08-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.290.30 Mainly Beta Beta Barrel Ku70; Chain: A; Domain 2 Ku70; Chain: A; Domain 2 2xnfA00
2L6UA 2XNFA 2L23A 2KY6A
chains in the Genus database with same CATH superfamily
2RT5A 2XNFA 3TIXB 1JEQB 1JEQA 2L6UA 1JEYB 2KY6A 1JEYA 1OW1A 2L23A
chains in the Genus database with same CATH topology
2RT5A 2XNFA 3TIXB 1JEQB 1JEQA 2L6UA 1JEYB 2KY6A 1JEYA 1OW1A 2L23A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L6U A;  2XNF A;  2L23 A;  2KY6 A; 
#chains in the Genus database with same CATH topology
 2RT5 A;  2XNF A;  3TIX B;  1JEQ B;  1JEQ A;  2L6U A;  1JEY B;  2KY6 A;  1JEY A;  1OW1 A;  2L23 A; 
#chains in the Genus database with same CATH homology
 2RT5 A;  2XNF A;  3TIX B;  1JEQ B;  1JEQ A;  2L6U A;  1JEY B;  2KY6 A;  1JEY A;  1OW1 A;  2L23 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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