2XPOA

Crystal structure of a spt6-iws1(spn1) complex from encephalitozoon cuniculi, form ii
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
139
structure length
139
Chain Sequence
MDPGTVLEISRSLKKRMQDILKKDNANNLEGRPATGKIENVEEISDILMSKALQESLLDEGILDEIKGWLEPLPDKSMPNIKIRKRLLDVLKTMKIHKEHLVTSGVGKIVYFYSINPKESKEVRASAKALVQKWTNEVF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of an Iws1/Spt6 Complex Reveals an Interaction Domain Conserved in Tfiis, Elongin a and Med26
pubmed doi rcsb
molecule tags Transcription
source organism Encephalitozoon cuniculi
molecule keywords IWS1
total genus 57
structure length 139
sequence length 139
chains with identical sequence C
ec nomenclature
pdb deposition date 2010-08-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08711 Med26 TFIIS helical bundle-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.10 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 2xpoA00
2XPPA 2XPOA 3F9KC 3O8ZA 3U88C 2N3AB 2XPNA 1WJTA 3HPGG 3OAKA 1EO0A 1Z9EA 3NFQA 2B4JC 3HPHE 2XPLA
chains in the Genus database with same CATH superfamily
4MCSA 5HKZA 2JBKA 3OAKA 4BPUB 4OC1A 1DE4C 1Z8LA 4A4BA 3OB1B 3D7GA 2XPNA 4GPLB 1WJTA 3BI0A 3BUWB 5F09A 3SJGA 3VGOA 4NGTA 5HKYA 4OC0A 2UV8G 3FECA 4OC5A 4P44A 2Y1MA 3F9KC 4NGQA 4NGNA 3S9MA 5D29A 3HPGG 3RBUA 2DLAA 2OOTA 3IWWA 3VRQA 4OC3A 2XEIA 3PLFB 4OMEA 4MCQA 3SJXA 4JYWA 4BTFA 3BUOB 4P45A 3VROA 3D7HA 2N3AB 3FEDA 3D7DA 2C6GA 3BUXB 2XPOA 4NGSA 2CIJA 4NGMA 5ELYA 2B4JC 3HPHE 3KASA 4P4JA 2Y1NA 4P4BA 4P4EA 3VRNA 5F13A 4BPWB 4MCRA 1CX8A 1YVHA 2VKZG 3ZNIA 4X3RA 1Z9EA 3NFQA 2XEGA 4NGPA 3FEEA 3SJFA 5BY0A 3U88C 3BI1A 3FF3A 4OC2A 4P4FA 3D7FA 5AXIA 3PFVA 4P4DA 1FBVA 3O8ZA 3BUNB 2XEFA 4NGRA 3VRPA 3OP0A 3PT1A 2XPPA 4P4IA 2JBJA 4OC4A 4LQGA 3VRRA 3BXMA 3BHXA 1B47A 4RR2B 2PVVA 4A4CA 1EO0A 4MCPA 2XPLA 2XEJA 5J3XA 2C6PA 3S9NA 4BPXB 3OB2B 3S9LA 3BUMB 4W9YA 3SJEA 2C6CA 5HKWA 2PVWA 4JZ0A 2CBLA 3HMJG 2OR4A
chains in the Genus database with same CATH topology
2XPPA 2XPOA 3F9KC 3O8ZA 3U88C 2N3AB 2XPNA 1WJTA 3HPGG 3OAKA 1EO0A 1Z9EA 3NFQA 2B4JC 3HPHE 2XPLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XPP A;  2XPO A;  3F9K C;  3O8Z A;  3U88 C;  2N3A B;  2XPN A;  1WJT A;  3HPG G;  3OAK A;  1EO0 A;  1Z9E A;  3NFQ A;  2B4J C;  3HPH E;  2XPL A; 
#chains in the Genus database with same CATH topology
 4MCS A;  5HKZ A;  2JBK A;  3OAK A;  4BPU B;  4OC1 A;  1DE4 C;  1Z8L A;  4A4B A;  3OB1 B;  3D7G A;  2XPN A;  4GPL B;  1WJT A;  3BI0 A;  3BUW B;  5F09 A;  3SJG A;  3VGO A;  4NGT A;  5HKY A;  4OC0 A;  2UV8 G;  3FEC A;  4OC5 A;  4P44 A;  2Y1M A;  3F9K C;  4NGQ A;  4NGN A;  3S9M A;  5D29 A;  3HPG G;  3RBU A;  2DLA A;  2OOT A;  3IWW A;  3VRQ A;  4OC3 A;  2XEI A;  3PLF B;  4OME A;  4MCQ A;  3SJX A;  4JYW A;  4BTF A;  3BUO B;  4P45 A;  3VRO A;  3D7H A;  2N3A B;  3FED A;  3D7D A;  2C6G A;  3BUX B;  2XPO A;  4NGS A;  2CIJ A;  4NGM A;  5ELY A;  2B4J C;  3HPH E;  3KAS A;  4P4J A;  2Y1N A;  4P4B A;  4P4E A;  3VRN A;  5F13 A;  4BPW B;  4MCR A;  1CX8 A;  1YVH A;  2VKZ G;  3ZNI A;  4X3R A;  1Z9E A;  3NFQ A;  2XEG A;  4NGP A;  3FEE A;  3SJF A;  5BY0 A;  3U88 C;  3BI1 A;  3FF3 A;  4OC2 A;  4P4F A;  3D7F A;  5AXI A;  3PFV A;  4P4D A;  1FBV A;  3O8Z A;  3BUN B;  2XEF A;  4NGR A;  3VRP A;  3OP0 A;  3PT1 A;  2XPP A;  4P4I A;  2JBJ A;  4OC4 A;  4LQG A;  3VRR A;  3BXM A;  3BHX A;  1B47 A;  4RR2 B;  2PVV A;  4A4C A;  1EO0 A;  4MCP A;  2XPL A;  2XEJ A;  5J3X A;  2C6P A;  3S9N A;  4BPX B;  3OB2 B;  3S9L A;  3BUM B;  4W9Y A;  3SJE A;  2C6C A;  5HKW A;  2PVW A;  4JZ0 A;  2CBL A;  3HMJ G;  2OR4 A; 
#chains in the Genus database with same CATH homology
 2XPP A;  2XPO A;  3F9K C;  3O8Z A;  3U88 C;  2N3A B;  2XPN A;  1WJT A;  3HPG G;  3OAK A;  1EO0 A;  1Z9E A;  3NFQ A;  2B4J C;  3HPH E;  2XPL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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