2XQWC

Structure of factor h domains 19-20 in complex with complement c3d
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
123
structure length
123
Chain Sequence
CGPPPPIDNGGITSFPLSVYAPASSVEYQCANLYQLEGNKRITCRNGQWSEPPKCLHPCVISREIMENYNIALRWTAKQKLYSRTGESVEFVCKRGYRLSSRSHTLRTTCWDGKLEYPTCAKR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords COMPLEMENT C3
publication title Dual Interaction of Factor H with C3D and Glycosaminoglycans in Host-Nonhost Discrimination by Complement.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Immune system
total genus 22
structure length 123
sequence length 123
ec nomenclature
pdb deposition date 2010-09-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 2xqwC01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 2xqwC02
2W80A 1OK9A 2JGXA 4AYMA 4YNXA 1HFIA 2ERJA 3INBC 4B2SA 4A5WB 3EJHA 1TPGA 2G7IA 2MCZA 1H03P 3KZJA 2IZ4A 2MCYA 3O8EB 4PZ5A 1OJWA 3CALA 3KXVA 3L89M 1Q3XA 2EC3A 2EHFA 3ERBA 4LOSA 1MD7A 2CG6A 5JPMG 3GOVA 1GKGA 1TPMA 3TVJA 1LY2A 4ZH1D 2IZ3A 3RJ3D 2CG7A 2KMSA 1QUBA 3ZD1A 2RKYA 4JHSA 3GXEA 4AYDA 1ZJKA 2YBYA 1OJYA 1NWVA 2QY0A 2XWBF 5FO8C 1G4GA 1MD8A 3OP8A 2RLPA 1H2PP 1QO6A 4LOTA 1U5MA 3ZD2A 1C1ZA 1FBRA 1PPQA 1UOTP 2RLQA 3IU3I 3MQLA 4IGDA 4B2RA 2JGWA 1GPZA 4FXGG 4K12A 3M7PA 1CKLA 1OK2A 1VVDA 2YRAA 2V8EA 1G4FA 1HFHA 4ONTD 2WIIC 2RKZA 2XRDA 1H2QP 4F4OC 1GHQB 2B5ID 2RL0A 4WJG2 1OK3A 1H04P 1VVCA 4KKDA 4MUCA 4J38B 4CSYA 2UWNA 2W81A 1TPNA 2XRBA 4AYEA 1GKNA 2O39C 2A55A 3SW0X 2JRAA 4DJZA 4C16A 1SRZA 2BZMA 5HYPA 1E88A 1E8BA 3NFPI 2LOJA 2KRIA 3IX0A 1SS2A 5HYUB 5HZPB 5HYTB 1Z92B 5I0QB 2CKUA 1QGBA 1HCCA 1OK1A 1OJVA 3OXUD 3R62A 3ZRZA 1O9AA 3OEDC 2XWJI 2XQWC 1E5GA 3T5OA 1ELVA 4AYIA
chains in the Genus database with same CATH superfamily
2W80A 1OK9A 2JGXA 4AYMA 4YNXA 1HFIA 2ERJA 5DN5A 3INBC 4B2SA 4A5WB 3EJHA 1TPGA 2G7IA 2MCZA 3WSYA 1H03P 3KZJA 1RLHA 2IZ4A 2MCYA 3O8EB 4PZ5A 1OJWA 3CALA 3KXVA 3L89M 1Q3XA 2EC3A 2EHFA 3ERBA 4LOSA 1MD7A 2CG6A 5JPMG 3GOVA 1GKGA 1TPMA 3TVJA 1LY2A 4ZH1D 2IZ3A 3RJ3D 2CG7A 2KMSA 1QUBA 3ZD1A 2RKYA 4JHSA 3GXEA 4AYDA 1ZJKA 2YBYA 1OJYA 1NWVA 2QY0A 2XWBF 5FO8C 1G4GA 1MD8A 3OP8A 2ZYCA 2RLPA 1H2PP 1QO6A 4LOTA 1U5MA 3ZD2A 1C1ZA 1FBRA 1PPQA 1UOTP 2RLQA 3IU3I 3MQLA 4IGDA 4B2RA 2Y8RA 2JGWA 1GPZA 3CI0J 4FXGG 4K12A 4APLA 3M7PA 1CKLA 1OK2A 4N7EA 1VVDA 2YRAA 2V8EA 1G4FA 3WSXA 1HFHA 4ONTD 4MSLA 2WIIC 2RKZA 2XRDA 1H2QP 3K3TA 4F4OC 1GHQB 2B5ID 2RL0A 4WJG2 1OK3A 1H04P 1VVCA 4KKDA 4MUCA 4J38B 4YIZA 4CSYA 2UWNA 2W81A 1TPNA 2XRBA 4AYEA 1GKNA 2Y8SA 2O39C 2A55A 3SW0X 2JRAA 2X2ZA 4BWCA 4DJZA 4C16A 1SRZA 2BZMA 5HYPA 1E88A 5DN4A 1E8BA 3NFPI 3FGRA 2LOJA 2KRIA 3IX0A 1SS2A 4PO7A 5HYUB 5HZPB 5HYTB 1Z92B 3F6KA 5I0QB 3ZLEA 2CKUA 2Y8TA 1QGBA 1HCCA 1OK1A 1OJVA 3OXUD 3R62A 3ZRZA 1O9AA 3ZLDA 3FGTA 2XWJI 3OEDC 2XQWC 1E5GA 3NJAA 2I2LA 3T5OA 1ELVA 3VWOA 4AYIA
chains in the Genus database with same CATH topology
2W80A 1OK9A 2JGXA 4AYMA 4YNXA 1HFIA 2ERJA 3INBC 4B2SA 4A5WB 3EJHA 1TPGA 2G7IA 2MCZA 1H03P 3KZJA 2IZ4A 2MCYA 3O8EB 4PZ5A 1OJWA 3CALA 3KXVA 3L89M 1Q3XA 2EC3A 2EHFA 3ERBA 4LOSA 1MD7A 2CG6A 5JPMG 3GOVA 1GKGA 1TPMA 3TVJA 1LY2A 4ZH1D 2IZ3A 3RJ3D 2CG7A 2KMSA 1QUBA 3ZD1A 2RKYA 4JHSA 3GXEA 4AYDA 1ZJKA 2YBYA 1OJYA 1NWVA 2QY0A 2XWBF 5FO8C 1G4GA 1MD8A 3OP8A 2RLPA 1H2PP 1QO6A 4LOTA 1U5MA 3ZD2A 1C1ZA 1FBRA 1PPQA 1UOTP 2RLQA 3IU3I 3MQLA 4IGDA 4B2RA 2JGWA 1GPZA 4FXGG 4K12A 3M7PA 1CKLA 1OK2A 1VVDA 2YRAA 2V8EA 1G4FA 1HFHA 4ONTD 2WIIC 2RKZA 2XRDA 1H2QP 4F4OC 1GHQB 2B5ID 2RL0A 4WJG2 1OK3A 1H04P 1VVCA 4KKDA 4MUCA 4J38B 4CSYA 2UWNA 2W81A 1TPNA 2XRBA 4AYEA 1GKNA 2O39C 2A55A 3SW0X 2JRAA 4DJZA 4C16A 1SRZA 2BZMA 5HYPA 1E88A 1E8BA 3NFPI 2LOJA 2KRIA 3IX0A 1SS2A 5HYUB 5HZPB 5HYTB 1Z92B 5I0QB 2CKUA 1QGBA 1HCCA 1OK1A 1OJVA 3OXUD 3R62A 3ZRZA 1O9AA 3OEDC 2XWJI 2XQWC 1E5GA 3T5OA 1ELVA 4AYIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W80 A;  1OK9 A;  2JGX A;  4AYM A;  4YNX A;  1HFI A;  2ERJ A;  3INB C;  4B2S A;  4A5W B;  3EJH A;  1TPG A;  2G7I A;  2MCZ A;  1H03 P;  3KZJ A;  2IZ4 A;  2MCY A;  3O8E B;  4PZ5 A;  1OJW A;  3CAL A;  3KXV A;  3L89 M;  1Q3X A;  2EC3 A;  2EHF A;  3ERB A;  4LOS A;  1MD7 A;  2CG6 A;  5JPM G;  3GOV A;  1GKG A;  1TPM A;  3TVJ A;  1LY2 A;  4ZH1 D;  2IZ3 A;  3RJ3 D;  2CG7 A;  2KMS A;  1QUB A;  3ZD1 A;  2RKY A;  4JHS A;  3GXE A;  4AYD A;  1ZJK A;  2YBY A;  1OJY A;  1NWV A;  2QY0 A;  2XWB F;  5FO8 C;  1G4G A;  1MD8 A;  3OP8 A;  2RLP A;  1H2P P;  1QO6 A;  4LOT A;  1U5M A;  3ZD2 A;  1C1Z A;  1FBR A;  1PPQ A;  1UOT P;  2RLQ A;  3IU3 I;  3MQL A;  4IGD A;  4B2R A;  2JGW A;  1GPZ A;  4FXG G;  4K12 A;  3M7P A;  1CKL A;  1OK2 A;  1VVD A;  2YRA A;  2V8E A;  1G4F A;  1HFH A;  4ONT D;  2WII C;  2RKZ A;  2XRD A;  1H2Q P;  4F4O C;  1GHQ B;  2B5I D;  2RL0 A;  4WJG 2;  1OK3 A;  1H04 P;  1VVC A;  4KKD A;  4MUC A;  4J38 B;  4CSY A;  2UWN A;  2W81 A;  1TPN A;  2XRB A;  4AYE A;  1GKN A;  2O39 C;  2A55 A;  3SW0 X;  2JRA A;  4DJZ A;  4C16 A;  1SRZ A;  2BZM A;  5HYP A;  1E88 A;  1E8B A;  3NFP I;  2LOJ A;  2KRI A;  3IX0 A;  1SS2 A;  5HYU B;  5HZP B;  5HYT B;  1Z92 B;  5I0Q B;  2CKU A;  1QGB A;  1HCC A;  1OK1 A;  1OJV A;  3OXU D;  3R62 A;  3ZRZ A;  1O9A A;  3OED C;  2XWJ I;  2XQW C;  1E5G A;  3T5O A;  1ELV A;  4AYI A; 
#chains in the Genus database with same CATH topology
 2W80 A;  1OK9 A;  2JGX A;  4AYM A;  4YNX A;  1HFI A;  2ERJ A;  5DN5 A;  3INB C;  4B2S A;  4A5W B;  3EJH A;  1TPG A;  2G7I A;  2MCZ A;  3WSY A;  1H03 P;  3KZJ A;  1RLH A;  2IZ4 A;  2MCY A;  3O8E B;  4PZ5 A;  1OJW A;  3CAL A;  3KXV A;  3L89 M;  1Q3X A;  2EC3 A;  2EHF A;  3ERB A;  4LOS A;  1MD7 A;  2CG6 A;  5JPM G;  3GOV A;  1GKG A;  1TPM A;  3TVJ A;  1LY2 A;  4ZH1 D;  2IZ3 A;  3RJ3 D;  2CG7 A;  2KMS A;  1QUB A;  3ZD1 A;  2RKY A;  4JHS A;  3GXE A;  4AYD A;  1ZJK A;  2YBY A;  1OJY A;  1NWV A;  2QY0 A;  2XWB F;  5FO8 C;  1G4G A;  1MD8 A;  3OP8 A;  2ZYC A;  2RLP A;  1H2P P;  1QO6 A;  4LOT A;  1U5M A;  3ZD2 A;  1C1Z A;  1FBR A;  1PPQ A;  1UOT P;  2RLQ A;  3IU3 I;  3MQL A;  4IGD A;  4B2R A;  2Y8R A;  2JGW A;  1GPZ A;  3CI0 J;  4FXG G;  4K12 A;  4APL A;  3M7P A;  1CKL A;  1OK2 A;  4N7E A;  1VVD A;  2YRA A;  2V8E A;  1G4F A;  3WSX A;  1HFH A;  4ONT D;  4MSL A;  2WII C;  2RKZ A;  2XRD A;  1H2Q P;  3K3T A;  4F4O C;  1GHQ B;  2B5I D;  2RL0 A;  4WJG 2;  1OK3 A;  1H04 P;  1VVC A;  4KKD A;  4MUC A;  4J38 B;  4YIZ A;  4CSY A;  2UWN A;  2W81 A;  1TPN A;  2XRB A;  4AYE A;  1GKN A;  2Y8S A;  2O39 C;  2A55 A;  3SW0 X;  2JRA A;  2X2Z A;  4BWC A;  4DJZ A;  4C16 A;  1SRZ A;  2BZM A;  5HYP A;  1E88 A;  5DN4 A;  1E8B A;  3NFP I;  3FGR A;  2LOJ A;  2KRI A;  3IX0 A;  1SS2 A;  4PO7 A;  5HYU B;  5HZP B;  5HYT B;  1Z92 B;  3F6K A;  5I0Q B;  3ZLE A;  2CKU A;  2Y8T A;  1QGB A;  1HCC A;  1OK1 A;  1OJV A;  3OXU D;  3R62 A;  3ZRZ A;  1O9A A;  3ZLD A;  3FGT A;  2XWJ I;  3OED C;  2XQW C;  1E5G A;  3NJA A;  2I2L A;  3T5O A;  1ELV A;  3VWO A;  4AYI A; 
#chains in the Genus database with same CATH homology
 2W80 A;  1OK9 A;  2JGX A;  4AYM A;  4YNX A;  1HFI A;  2ERJ A;  3INB C;  4B2S A;  4A5W B;  3EJH A;  1TPG A;  2G7I A;  2MCZ A;  1H03 P;  3KZJ A;  2IZ4 A;  2MCY A;  3O8E B;  4PZ5 A;  1OJW A;  3CAL A;  3KXV A;  3L89 M;  1Q3X A;  2EC3 A;  2EHF A;  3ERB A;  4LOS A;  1MD7 A;  2CG6 A;  5JPM G;  3GOV A;  1GKG A;  1TPM A;  3TVJ A;  1LY2 A;  4ZH1 D;  2IZ3 A;  3RJ3 D;  2CG7 A;  2KMS A;  1QUB A;  3ZD1 A;  2RKY A;  4JHS A;  3GXE A;  4AYD A;  1ZJK A;  2YBY A;  1OJY A;  1NWV A;  2QY0 A;  2XWB F;  5FO8 C;  1G4G A;  1MD8 A;  3OP8 A;  2RLP A;  1H2P P;  1QO6 A;  4LOT A;  1U5M A;  3ZD2 A;  1C1Z A;  1FBR A;  1PPQ A;  1UOT P;  2RLQ A;  3IU3 I;  3MQL A;  4IGD A;  4B2R A;  2JGW A;  1GPZ A;  4FXG G;  4K12 A;  3M7P A;  1CKL A;  1OK2 A;  1VVD A;  2YRA A;  2V8E A;  1G4F A;  1HFH A;  4ONT D;  2WII C;  2RKZ A;  2XRD A;  1H2Q P;  4F4O C;  1GHQ B;  2B5I D;  2RL0 A;  4WJG 2;  1OK3 A;  1H04 P;  1VVC A;  4KKD A;  4MUC A;  4J38 B;  4CSY A;  2UWN A;  2W81 A;  1TPN A;  2XRB A;  4AYE A;  1GKN A;  2O39 C;  2A55 A;  3SW0 X;  2JRA A;  4DJZ A;  4C16 A;  1SRZ A;  2BZM A;  5HYP A;  1E88 A;  1E8B A;  3NFP I;  2LOJ A;  2KRI A;  3IX0 A;  1SS2 A;  5HYU B;  5HZP B;  5HYT B;  1Z92 B;  5I0Q B;  2CKU A;  1QGB A;  1HCC A;  1OK1 A;  1OJV A;  3OXU D;  3R62 A;  3ZRZ A;  1O9A A;  3OED C;  2XWJ I;  2XQW C;  1E5G A;  3T5O A;  1ELV A;  4AYI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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