2XSWA

Crystal structure of human inpp5e
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
343
structure length
340
Chain Sequence
GALLGADELARYFPDRNVALFVATWNMQGQKELPPSLDEFLLPAEADYAQDLYVIGVQEGCSDRREWETRLQETLGPHYVLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTNPYRSSAADVTTRFDEVFWFGDFNFRLSGGRTVVDALLCVVDVPALLQHDQLIREMRKGSIFKGFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHKGDICPVSYSSCPGIKTSDHRPVYGLFRVKVRPGRDNIPLAAGKFDRELYLLGIKRRISA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Human Inpp5E
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords 72 KDA INOSITOL POLYPHOSPHATE 5-PHOSPHATASE
total genus 112
structure length 340
sequence length 343
chains with identical sequence B
ec nomenclature ec 3.1.3.36: Phosphoinositide 5-phosphatase.
pdb deposition date 2010-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 2xswA00
3G6SA 5EWTA 1Y21A 4C1RA 3NGQA 5HT2A 2DDSA 2F2FB 1DNKA 2V0RA 5CFGA 2A3ZB 4F1HA 4L1YA 3G0AA 3G3CA 1BIXA 1ZWXA 2DDRA 5CFEA 3TEBA 3I41A 3I48A 4AWNA 4RUWA 5DFFA 3G91A 1I9YA 2A41B 5INLA 2JC4A 3I5VA 4L21A 3U8UA 4B5HA 3N9VA 4B5JA 3NR8A 3K55A 4QHEA 5DV2A 3L1WA 1AKOA 2EI9A 5DFJA 4PUQA 2ISIA 3FZIA 2DNJA 1I9ZA 4B5GA 3G8VA 5J3PA 1SI6X 2A42B 5J3SA 5INPA 4CMLA 3G2CA 3MPRA 3G0RA 1WDUA 2F1NA 3G38A 4F1IA 3G3YA 4F1HB 1DE8A 4GYZA 4JG3A 5J42A 3MTCA 2VOAA 4GZ1A 1ATND 2D1KB 2UYRX 5INOA 4B5IA 4CMNA 3WCXA 4FVAA 2V0SA 5J3ZA 2A40B 2XSWA 3DNIA 4GZ0A 4QH9A 3NGOA 3I46A 3G2DA 5A7IA 3NGNA 4GEWA 4K6LF 5DFIA 5INQA 1VYBA 1E9NA 4B5MA 3GA6A 1NTFA 2IMQX 2J63A 2O3HA 1DE9A 2DDTA 4L20A 4A9CA 5INMA 5A7JA 2JC5A 2O3CA 3W2XA 5DG0A 5DFHA 1YJHA 4F1RA 3W3DB 4L1ZA 4FPVA 5J8NA 3G4TA 4LNDA 4IEMA 1DEWA 4QHDA 4B5FA 3G1KA 4GZ2A 3W2YA 1SR4B 1HD7A 3CJCD 5INKA 5INNA 3G00A 5DV4A
chains in the Genus database with same CATH superfamily
3G6SA 5EWTA 1Y21A 4C1RA 3NGQA 5HT2A 2DDSA 2F2FB 1DNKA 2V0RA 5CFGA 2A3ZB 4F1HA 4L1YA 3G0AA 3G3CA 1BIXA 1ZWXA 2DDRA 5CFEA 3TEBA 3I41A 3I48A 4AWNA 4RUWA 5DFFA 3G91A 1I9YA 2A41B 5INLA 2JC4A 3I5VA 4L21A 3U8UA 4B5HA 3N9VA 4B5JA 3NR8A 3K55A 4QHEA 5DV2A 3L1WA 1AKOA 2EI9A 5DFJA 4PUQA 2ISIA 3FZIA 2DNJA 1I9ZA 4B5GA 3G8VA 5J3PA 1SI6X 2A42B 5J3SA 5INPA 4CMLA 3G2CA 3MPRA 3G0RA 1WDUA 2F1NA 3G38A 4F1IA 3G3YA 4F1HB 1DE8A 4GYZA 4JG3A 5J42A 3MTCA 2VOAA 4GZ1A 1ATND 2D1KB 2UYRX 5INOA 4B5IA 4CMNA 3WCXA 4FVAA 2V0SA 5J3ZA 2A40B 2XSWA 3DNIA 4GZ0A 4QH9A 3NGOA 3I46A 3G2DA 5A7IA 3NGNA 4GEWA 4K6LF 5DFIA 5INQA 1VYBA 1E9NA 4B5MA 3GA6A 1NTFA 2IMQX 2J63A 2O3HA 1DE9A 2DDTA 4L20A 4A9CA 5INMA 5A7JA 2JC5A 2O3CA 3W2XA 5DG0A 5DFHA 1YJHA 4F1RA 3W3DB 4L1ZA 4FPVA 5J8NA 3G4TA 4LNDA 4IEMA 1DEWA 4QHDA 4B5FA 3G1KA 4GZ2A 3W2YA 1SR4B 1HD7A 3CJCD 5INKA 5INNA 3G00A 5DV4A
chains in the Genus database with same CATH topology
3G6SA 5EWTA 1Y21A 4C1RA 3NGQA 5HT2A 2DDSA 2F2FB 1DNKA 2V0RA 5CFGA 2A3ZB 4F1HA 4L1YA 3G0AA 3G3CA 1BIXA 1ZWXA 2DDRA 5CFEA 3TEBA 3I41A 3I48A 4AWNA 4RUWA 5DFFA 3G91A 1I9YA 2A41B 5INLA 2JC4A 3I5VA 4L21A 3U8UA 4B5HA 3N9VA 4B5JA 3NR8A 3K55A 4QHEA 5DV2A 3L1WA 1AKOA 2EI9A 5DFJA 4PUQA 2ISIA 3FZIA 2DNJA 1I9ZA 4B5GA 3G8VA 5J3PA 1SI6X 2A42B 5J3SA 5INPA 4CMLA 3G2CA 3MPRA 3G0RA 1WDUA 2F1NA 3G38A 4F1IA 3G3YA 4F1HB 1DE8A 4GYZA 4JG3A 5J42A 3MTCA 2VOAA 4GZ1A 1ATND 2D1KB 2UYRX 5INOA 4B5IA 4CMNA 3WCXA 4FVAA 2V0SA 5J3ZA 2A40B 2XSWA 3DNIA 4GZ0A 4QH9A 3NGOA 3I46A 3G2DA 5A7IA 3NGNA 4GEWA 4K6LF 5DFIA 5INQA 1VYBA 1E9NA 4B5MA 3GA6A 1NTFA 2IMQX 2J63A 2O3HA 1DE9A 2DDTA 4L20A 4A9CA 5INMA 5A7JA 2JC5A 2O3CA 3W2XA 5DG0A 5DFHA 1YJHA 4F1RA 3W3DB 4L1ZA 4FPVA 5J8NA 3G4TA 4LNDA 4IEMA 1DEWA 4QHDA 4B5FA 3G1KA 4GZ2A 3W2YA 1SR4B 1HD7A 3CJCD 5INKA 5INNA 3G00A 5DV4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G6S A;  5EWT A;  1Y21 A;  4C1R A;  3NGQ A;  5HT2 A;  2DDS A;  2F2F B;  1DNK A;  2V0R A;  5CFG A;  2A3Z B;  4F1H A;  4L1Y A;  3G0A A;  3G3C A;  1BIX A;  1ZWX A;  2DDR A;  5CFE A;  3TEB A;  3I41 A;  3I48 A;  4AWN A;  4RUW A;  5DFF A;  3G91 A;  1I9Y A;  2A41 B;  5INL A;  2JC4 A;  3I5V A;  4L21 A;  3U8U A;  4B5H A;  3N9V A;  4B5J A;  3NR8 A;  3K55 A;  4QHE A;  5DV2 A;  3L1W A;  1AKO A;  2EI9 A;  5DFJ A;  4PUQ A;  2ISI A;  3FZI A;  2DNJ A;  1I9Z A;  4B5G A;  3G8V A;  5J3P A;  1SI6 X;  2A42 B;  5J3S A;  5INP A;  4CML A;  3G2C A;  3MPR A;  3G0R A;  1WDU A;  2F1N A;  3G38 A;  4F1I A;  3G3Y A;  4F1H B;  1DE8 A;  4GYZ A;  4JG3 A;  5J42 A;  3MTC A;  2VOA A;  4GZ1 A;  1ATN D;  2D1K B;  2UYR X;  5INO A;  4B5I A;  4CMN A;  3WCX A;  4FVA A;  2V0S A;  5J3Z A;  2A40 B;  2XSW A;  3DNI A;  4GZ0 A;  4QH9 A;  3NGO A;  3I46 A;  3G2D A;  5A7I A;  3NGN A;  4GEW A;  4K6L F;  5DFI A;  5INQ A;  1VYB A;  1E9N A;  4B5M A;  3GA6 A;  1NTF A;  2IMQ X;  2J63 A;  2O3H A;  1DE9 A;  2DDT A;  4L20 A;  4A9C A;  5INM A;  5A7J A;  2JC5 A;  2O3C A;  3W2X A;  5DG0 A;  5DFH A;  1YJH A;  4F1R A;  3W3D B;  4L1Z A;  4FPV A;  5J8N A;  3G4T A;  4LND A;  4IEM A;  1DEW A;  4QHD A;  4B5F A;  3G1K A;  4GZ2 A;  3W2Y A;  1SR4 B;  1HD7 A;  3CJC D;  5INK A;  5INN A;  3G00 A;  5DV4 A; 
#chains in the Genus database with same CATH topology
 3G6S A;  5EWT A;  1Y21 A;  4C1R A;  3NGQ A;  5HT2 A;  2DDS A;  2F2F B;  1DNK A;  2V0R A;  5CFG A;  2A3Z B;  4F1H A;  4L1Y A;  3G0A A;  3G3C A;  1BIX A;  1ZWX A;  2DDR A;  5CFE A;  3TEB A;  3I41 A;  3I48 A;  4AWN A;  4RUW A;  5DFF A;  3G91 A;  1I9Y A;  2A41 B;  5INL A;  2JC4 A;  3I5V A;  4L21 A;  3U8U A;  4B5H A;  3N9V A;  4B5J A;  3NR8 A;  3K55 A;  4QHE A;  5DV2 A;  3L1W A;  1AKO A;  2EI9 A;  5DFJ A;  4PUQ A;  2ISI A;  3FZI A;  2DNJ A;  1I9Z A;  4B5G A;  3G8V A;  5J3P A;  1SI6 X;  2A42 B;  5J3S A;  5INP A;  4CML A;  3G2C A;  3MPR A;  3G0R A;  1WDU A;  2F1N A;  3G38 A;  4F1I A;  3G3Y A;  4F1H B;  1DE8 A;  4GYZ A;  4JG3 A;  5J42 A;  3MTC A;  2VOA A;  4GZ1 A;  1ATN D;  2D1K B;  2UYR X;  5INO A;  4B5I A;  4CMN A;  3WCX A;  4FVA A;  2V0S A;  5J3Z A;  2A40 B;  2XSW A;  3DNI A;  4GZ0 A;  4QH9 A;  3NGO A;  3I46 A;  3G2D A;  5A7I A;  3NGN A;  4GEW A;  4K6L F;  5DFI A;  5INQ A;  1VYB A;  1E9N A;  4B5M A;  3GA6 A;  1NTF A;  2IMQ X;  2J63 A;  2O3H A;  1DE9 A;  2DDT A;  4L20 A;  4A9C A;  5INM A;  5A7J A;  2JC5 A;  2O3C A;  3W2X A;  5DG0 A;  5DFH A;  1YJH A;  4F1R A;  3W3D B;  4L1Z A;  4FPV A;  5J8N A;  3G4T A;  4LND A;  4IEM A;  1DEW A;  4QHD A;  4B5F A;  3G1K A;  4GZ2 A;  3W2Y A;  1SR4 B;  1HD7 A;  3CJC D;  5INK A;  5INN A;  3G00 A;  5DV4 A; 
#chains in the Genus database with same CATH homology
 3G6S A;  5EWT A;  1Y21 A;  4C1R A;  3NGQ A;  5HT2 A;  2DDS A;  2F2F B;  1DNK A;  2V0R A;  5CFG A;  2A3Z B;  4F1H A;  4L1Y A;  3G0A A;  3G3C A;  1BIX A;  1ZWX A;  2DDR A;  5CFE A;  3TEB A;  3I41 A;  3I48 A;  4AWN A;  4RUW A;  5DFF A;  3G91 A;  1I9Y A;  2A41 B;  5INL A;  2JC4 A;  3I5V A;  4L21 A;  3U8U A;  4B5H A;  3N9V A;  4B5J A;  3NR8 A;  3K55 A;  4QHE A;  5DV2 A;  3L1W A;  1AKO A;  2EI9 A;  5DFJ A;  4PUQ A;  2ISI A;  3FZI A;  2DNJ A;  1I9Z A;  4B5G A;  3G8V A;  5J3P A;  1SI6 X;  2A42 B;  5J3S A;  5INP A;  4CML A;  3G2C A;  3MPR A;  3G0R A;  1WDU A;  2F1N A;  3G38 A;  4F1I A;  3G3Y A;  4F1H B;  1DE8 A;  4GYZ A;  4JG3 A;  5J42 A;  3MTC A;  2VOA A;  4GZ1 A;  1ATN D;  2D1K B;  2UYR X;  5INO A;  4B5I A;  4CMN A;  3WCX A;  4FVA A;  2V0S A;  5J3Z A;  2A40 B;  2XSW A;  3DNI A;  4GZ0 A;  4QH9 A;  3NGO A;  3I46 A;  3G2D A;  5A7I A;  3NGN A;  4GEW A;  4K6L F;  5DFI A;  5INQ A;  1VYB A;  1E9N A;  4B5M A;  3GA6 A;  1NTF A;  2IMQ X;  2J63 A;  2O3H A;  1DE9 A;  2DDT A;  4L20 A;  4A9C A;  5INM A;  5A7J A;  2JC5 A;  2O3C A;  3W2X A;  5DG0 A;  5DFH A;  1YJH A;  4F1R A;  3W3D B;  4L1Z A;  4FPV A;  5J8N A;  3G4T A;  4LND A;  4IEM A;  1DEW A;  4QHD A;  4B5F A;  3G1K A;  4GZ2 A;  3W2Y A;  1SR4 B;  1HD7 A;  3CJC D;  5INK A;  5INN A;  3G00 A;  5DV4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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