2XU0A

Crystal structure of the nts-dbl1(alpha-1) domain of the plasmodium falciparum membrane protein 1 (pfemp1) from the varo strain.
Total Genus 169
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
169
sequence length
476
structure length
447
Chain Sequence
SPTLSESHKSARNVLENIGIKIYNQEIKKKNPYEQQLKGTLDGNSCNLDHLFGRKPCYGREQNRFDENAEAYCNSDKIRGNENNANGAACAPPRRRHICDQNLEFLDNKNTNTAHDLLGNVLVTAKYEGNYIVNDHPDKNSNGNKAGICTSLARSFADIGDIVRGRDMFLPNKDDKVQKGLQVVFKKIYKSLTPEARKHYAHGDGSGNYAKLREDWWTINREQIWKALTCSAPYYADYFRKGSDGTLHFSSHGKCGHNEGAPPTYLDYVPQFLRWFEEWSEEFCRIKKIKIDKVKKECRDEQNKKYCSGDGHDCTQTNLAHNQIFVDLDCPRCQDQCIKYNEWIVKKLEEFYKQNLKYSMEIQKWKKTKNNYYDKEFYENLDKKSYSTIDKFLNLLNNGKHCHDNKDEKNKIDFNKPIKTFSISEYCKTCPLYGVTCTNRGICIHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Membrane protein
molecule keywords ERYTHROCYTE MEMBRANE PROTEIN 1
publication title Structure of a Plasmodium Falciparum Pfemp1 Rosetting Domain Reveals a Role for the N-Terminal Segment in Heparin-Mediated Rosette Inhibition.
pubmed doi rcsb
source organism Plasmodium falciparum palo alto/uganda
total genus 169
structure length 447
sequence length 476
ec nomenclature
pdb deposition date 2010-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF05424 Duffy_binding Duffy binding domain
A PF15447 NTS N-terminal segments of PfEMP1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.20 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like 5 helical Cullin repeat like 2xu0A00
3CMLA 4NUVA 4YFSA 2Y8DA 3CPZA 3BQLA 3BQKA 4NUUA 2WAUA 3RRCA 3BQIA 5F3JA 2XU0A
chains in the Genus database with same CATH superfamily
4APFB 2Y8DA 4AP2B 3CPZA 1LDKA 2WZKA 4EOZB 1U6GA 2XU0A 3RTRA 3DPLC 4F52A 3BQKA 4WQOD 3DQVC 4HXIB 5F3JA 4N9F3 3CMLA 4NUVA 2PFVA 4YFSA 1LDKB 2B1EA 4P5OA 3BQLA 4JGHD 4NUUA 4A64A 2WAUA 3RRCA 3BQIA 1LDJA
chains in the Genus database with same CATH topology
3CMLA 4NUVA 2PFVA 4YFSA 2Y8DA 3CPZA 3BQLA 3BQKA 4NUUA 2B1EA 2WAUA 3RRCA 3BQIA 5F3JA 2XU0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CML A;  4NUV A;  4YFS A;  2Y8D A;  3CPZ A;  3BQL A;  3BQK A;  4NUU A;  2WAU A;  3RRC A;  3BQI A;  5F3J A;  2XU0 A; 
#chains in the Genus database with same CATH topology
 4APF B;  2Y8D A;  4AP2 B;  3CPZ A;  1LDK A;  2WZK A;  4EOZ B;  1U6G A;  2XU0 A;  3RTR A;  3DPL C;  4F52 A;  3BQK A;  4WQO D;  3DQV C;  4HXI B;  5F3J A;  4N9F 3;  3CML A;  4NUV A;  2PFV A;  4YFS A;  1LDK B;  2B1E A;  4P5O A;  3BQL A;  4JGH D;  4NUU A;  4A64 A;  2WAU A;  3RRC A;  3BQI A;  1LDJ A; 
#chains in the Genus database with same CATH homology
 3CML A;  4NUV A;  2PFV A;  4YFS A;  2Y8D A;  3CPZ A;  3BQL A;  3BQK A;  4NUU A;  2B1E A;  2WAU A;  3RRC A;  3BQI A;  5F3J A;  2XU0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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